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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:decreased transitional stage B cell number
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Accession:MP:0008190 term browser browse the term
Definition:reduced number of immature B cells of an intermediate stage between the pre-B cell stage and the mature naive stage; transitional B cells express surface immunoglobulin, and are subject to the process of B cell selection
Synonyms:exact_synonym: decreased transitional B cell number;   decreased transitional stage B lymphocyte number



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decreased transitional stage B cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arhgdia Rho GDP dissociation inhibitor alpha IAGP MGI PMID:17142749 NCBI chr11:120,468,925...120,472,450
Ensembl chr11:120,468,930...120,472,450
JBrowse link
G Arhgdib Rho, GDP dissociation inhibitor beta IAGP MGI PMID:17142749 NCBI chr 6:136,900,653...136,918,895
Ensembl chr 6:136,900,653...136,918,897
JBrowse link
G Arid3a AT-rich interaction domain 3A IAGP MGI PMID:21199920 NCBI chr10:79,762,877...79,790,852
Ensembl chr10:79,762,877...79,790,852
JBrowse link
G Arid3b AT-rich interaction domain 3B IAGP MGI PMID:27537840 NCBI chr 9:57,697,636...57,744,130
Ensembl chr 9:57,697,636...57,744,076
JBrowse link
G Atp11c ATPase, class VI, type 11C IAGP MGI PMID:21423172 NCBI chr  X:59,268,643...59,450,041
Ensembl chr  X:59,268,650...59,636,304
JBrowse link
G Bach2 BTB and CNC homology, basic leucine zipper transcription factor 2 IEA MGI NCBI chr 4:32,238,413...32,586,109
Ensembl chr 4:32,238,804...32,586,108
JBrowse link
G Blnk B cell linker IAGP MGI PMID:16481047 NCBI chr19:40,917,371...40,982,664
Ensembl chr19:40,917,371...40,982,978
JBrowse link
G Bmal1 basic helix-loop-helix ARNT like 1 IAGP MGI PMID:16925591 NCBI chr 7:112,777,820...112,913,333
Ensembl chr 7:112,806,672...112,913,333
JBrowse link
G Btk Bruton agammaglobulinemia tyrosine kinase IAGP MGI PMID:17105816 NCBI chr  X:133,443,083...133,484,366
Ensembl chr  X:133,443,085...133,484,319
JBrowse link
G Cd19 CD19 antigen IAGP MGI PMID:12753744 PMID:14564011 PMID:18538592 NCBI chr 7:126,007,620...126,016,401
Ensembl chr 7:126,007,622...126,014,061
JBrowse link
G Cd22 CD22 antigen IAGP MGI PMID:23836650 NCBI chr 7:30,564,829...30,579,767
Ensembl chr 7:30,564,827...30,579,767
JBrowse link
G Cd79a CD79A antigen (immunoglobulin-associated alpha) IAGP MGI PMID:11136817 PMID:22213803 NCBI chr 7:24,596,922...24,601,283
Ensembl chr 7:24,596,806...24,601,622
JBrowse link
G Cd79b CD79B antigen IAGP MGI PMID:11136817 NCBI chr11:106,202,167...106,205,388
Ensembl chr11:106,202,167...106,205,588
JBrowse link
G Dsg3 desmoglein 3 IAGP MGI PMID:25542773 NCBI chr18:20,643,331...20,674,367
Ensembl chr18:20,643,331...20,680,516
JBrowse link
G Ebf1 early B cell factor 1 IAGP MGI PMID:22431510 NCBI chr11:44,502,738...44,898,923
Ensembl chr11:44,508,144...44,898,918
JBrowse link
G Erg ETS transcription factor IAGP MGI PMID:18500345 NCBI chr16:95,160,028...95,387,452
Ensembl chr16:95,160,028...95,387,452
JBrowse link
G Fas Fas cell surface death receptor IAGP MGI PMID:17073941 NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172
JBrowse link
G Fnip1 folliculin interacting protein 1 IAGP MGI PMID:22709692 NCBI chr11:54,328,071...54,409,067
Ensembl chr11:54,329,025...54,409,061
JBrowse link
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano IAGP MGI PMID:17536012 NCBI chr 6:113,044,389...113,054,205
Ensembl chr 6:113,043,843...113,055,336
JBrowse link
G Huwe1 HECT, UBA and WWE domain containing 1 IAGP MGI PMID:22213803 NCBI chr  X:150,583,779...150,718,413
Ensembl chr  X:150,583,803...150,718,413
JBrowse link
G Igh immunoglobulin heavy chain complex IAGP MGI PMID:16754718 PMID:17420268 PMID:19050258 NCBI chr12:113,222,388...115,973,574 JBrowse link
G Ighm immunoglobulin heavy constant mu IAGP MGI PMID:20133609 NCBI chr12:113,382,446...113,386,350
Ensembl chr12:113,382,178...113,386,350
JBrowse link
G Lrrc8a leucine rich repeat containing 8A VRAC subunit A IAGP MGI PMID:24752297 NCBI chr 2:30,127,781...30,153,802
Ensembl chr 2:30,127,727...30,153,802
JBrowse link
G Lta lymphotoxin A IAGP MGI PMID:18384745 NCBI chr17:35,422,141...35,424,568
Ensembl chr17:35,422,141...35,424,327
JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase IAGP MGI PMID:19150426 PMID:19201855 NCBI chr 4:3,676,865...3,791,613
Ensembl chr 4:3,678,115...3,813,122
JBrowse link
G Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100 IAGP MGI PMID:18025196 NCBI chr19:46,285,478...46,300,839
Ensembl chr19:46,292,759...46,300,824
JBrowse link
G Notch2 notch 2 IAGP MGI PMID:12753744 NCBI chr 3:97,920,854...98,057,683
Ensembl chr 3:97,920,843...98,057,677
JBrowse link
G Npy1r neuropeptide Y receptor Y1 IAGP MGI PMID:16330815 NCBI chr 8:67,149,595...67,159,452
Ensembl chr 8:67,149,844...67,159,444
JBrowse link
G Paxx non-homologous end joining factor IAGP MGI PMID:27798842 NCBI chr 2:25,345,132...25,352,666
Ensembl chr 2:25,345,153...25,351,106
JBrowse link
G Pdia6 protein disulfide isomerase associated 6 IAGP MGI PMID:31985756 NCBI chr12:17,316,590...17,334,786
Ensembl chr12:17,316,546...17,334,771
JBrowse link
G Plcg2 phospholipase C, gamma 2 IAGP MGI PMID:15845450 NCBI chr 8:118,225,014...118,361,881
Ensembl chr 8:118,225,030...118,361,881
JBrowse link
G Polr2a polymerase (RNA) II (DNA directed) polypeptide A IAGP MGI PMID:22431510 NCBI chr11:69,624,823...69,649,459
Ensembl chr11:69,624,823...69,649,463
JBrowse link
G Ppp2r3c protein phosphatase 2, regulatory subunit B'', gamma IAGP MGI PMID:16129705 NCBI chr12:55,327,594...55,350,024
Ensembl chr12:55,325,776...55,349,783
JBrowse link
G Ptch1 patched 1 IAGP MGI PMID:17536012 NCBI chr13:63,656,142...63,721,274
Ensembl chr13:63,656,142...63,721,412
JBrowse link
G Rac1 Rac family small GTPase 1 IAGP MGI PMID:14564011 NCBI chr 5:143,491,236...143,513,786
Ensembl chr 5:143,489,389...143,513,791
JBrowse link
G Rac2 Rac family small GTPase 2 IAGP MGI PMID:14564011 NCBI chr15:78,443,369...78,456,983
Ensembl chr15:78,443,367...78,456,983
JBrowse link
G Racgap1 Rac GTPase-activating protein 1 IAGP MGI PMID:18541143 NCBI chr15:99,518,377...99,549,504
Ensembl chr15:99,518,377...99,549,537
JBrowse link
G Sh2d1a SH2 domain containing 1A IAGP MGI PMID:15749842 NCBI chr  X:41,591,442...41,610,974
Ensembl chr  X:41,591,330...41,618,207
JBrowse link
G Sh3bp2 SH3-domain binding protein 2 IAGP MGI PMID:17283041 NCBI chr 5:34,683,128...34,720,983
Ensembl chr 5:34,683,182...34,720,985
JBrowse link
G St6gal1 beta galactoside alpha 2,6 sialyltransferase 1 IAGP MGI PMID:18354178 NCBI chr16:23,043,478...23,179,100
Ensembl chr16:23,043,490...23,179,100
JBrowse link
G Syk spleen tyrosine kinase IAGP MGI PMID:22728826 NCBI chr13:52,736,670...52,802,828
Ensembl chr13:52,737,209...52,802,828
JBrowse link
G Tcf3 transcription factor 3 IAGP MGI PMID:18538592 NCBI chr10:80,245,375...80,269,814
Ensembl chr10:80,245,348...80,269,481
JBrowse link
G Tnfsf13b tumor necrosis factor (ligand) superfamily, member 13b IAGP MGI PMID:18624351 NCBI chr 8:10,056,637...10,086,000
Ensembl chr 8:10,056,467...10,089,072
JBrowse link
G Traf3ip2 TRAF3 interacting protein 2 IAGP MGI PMID:18624351 NCBI chr10:39,488,930...39,531,303
Ensembl chr10:39,488,930...39,531,303
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 IAGP MGI PMID:11257141 NCBI chr 3:115,903,669...115,923,337
Ensembl chr 3:115,903,598...115,923,337
JBrowse link
G Zbtb1 zinc finger and BTB domain containing 1 IAGP MGI PMID:22201126 NCBI chr12:76,416,825...76,443,729
Ensembl chr12:76,417,040...76,443,724
JBrowse link
absent transitional stage B cells term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnfrsf13c tumor necrosis factor receptor superfamily, member 13c IAGP MGI PMID:15294946 NCBI chr15:82,105,943...82,108,581
Ensembl chr15:82,105,944...82,108,570
JBrowse link
decreased transitional stage T1 B cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adgrg3 adhesion G protein-coupled receptor G3 IAGP MGI PMID:24113187 NCBI chr 8:95,743,742...95,771,878
Ensembl chr 8:95,744,320...95,771,878
JBrowse link
G Arid3a AT-rich interaction domain 3A IAGP MGI PMID:21199920 NCBI chr10:79,762,877...79,790,852
Ensembl chr10:79,762,877...79,790,852
JBrowse link
G Atp11c ATPase, class VI, type 11C IAGP MGI PMID:21423172 NCBI chr  X:59,268,643...59,450,041
Ensembl chr  X:59,268,650...59,636,304
JBrowse link
G Bcl3 B cell leukemia/lymphoma 3 IAGP MGI PMID:24244019 NCBI chr 7:19,542,387...19,556,691
Ensembl chr 7:19,542,387...19,556,695
JBrowse link
G Card11 caspase recruitment domain family, member 11 IAGP MGI PMID:31784498 NCBI chr 5:140,858,109...140,986,398
Ensembl chr 5:140,858,745...140,986,337
JBrowse link
G Cd19 CD19 antigen IAGP MGI PMID:24242374 PMID:25238757 NCBI chr 7:126,007,620...126,016,401
Ensembl chr 7:126,007,622...126,014,061
JBrowse link
G Cd22 CD22 antigen IAGP MGI PMID:22965838 NCBI chr 7:30,564,829...30,579,767
Ensembl chr 7:30,564,827...30,579,767
JBrowse link
G Cd79a CD79A antigen (immunoglobulin-associated alpha) IAGP MGI PMID:21427701 NCBI chr 7:24,596,922...24,601,283
Ensembl chr 7:24,596,806...24,601,622
JBrowse link
G Cttnbp2 cortactin binding protein 2 IEA MGI NCBI chr 6:18,366,470...18,515,216
Ensembl chr 6:18,366,477...18,514,842
JBrowse link
G Duoxa2 dual oxidase maturation factor 2 IEA MGI NCBI chr 2:122,129,381...122,133,088
Ensembl chr 2:122,129,381...122,133,366
JBrowse link
G Ell2 elongation factor for RNA polymerase II 2 IAGP MGI PMID:25238757 NCBI chr13:75,855,603...75,920,480
Ensembl chr13:75,854,876...75,920,483
JBrowse link
G Grb2 growth factor receptor bound protein 2 IAGP MGI PMID:21427701 NCBI chr11:115,534,871...115,599,423
Ensembl chr11:115,534,871...115,599,423
JBrowse link
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano IAGP MGI PMID:24242374 NCBI chr 6:113,044,389...113,054,205
Ensembl chr 6:113,043,843...113,055,336
JBrowse link
G Hax1 HCLS1 associated X-1 IAGP MGI PMID:20865787 NCBI chr 3:89,902,753...89,906,023
Ensembl chr 3:89,902,753...89,906,087
JBrowse link
G Igk immunoglobulin kappa chain complex IAGP MGI PMID:11869685 NCBI chr 6:67,532,620...70,703,738 JBrowse link
G Iglc1 immunoglobulin lambda constant 1 IAGP MGI PMID:11869685 NCBI chr16:18,880,502...18,880,821
Ensembl chr16:18,880,368...18,880,821
JBrowse link
G Kdelr1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 IAGP MGI PMID:26438836 NCBI chr 7:45,522,264...45,533,150
Ensembl chr 7:45,522,196...45,533,156
JBrowse link
G Map3k14 mitogen-activated protein kinase kinase kinase 14 IAGP MGI PMID:26116508 NCBI chr11:103,110,590...103,158,227
Ensembl chr11:103,110,588...103,158,298
JBrowse link
G Mtor mechanistic target of rapamycin kinase IAGP MGI PMID:21079150 NCBI chr 4:148,533,039...148,642,142
Ensembl chr 4:148,533,068...148,642,140
JBrowse link
G Pepd peptidase D IEA MGI NCBI chr 7:34,611,832...34,744,131
Ensembl chr 7:34,611,804...34,744,133
JBrowse link
G Spns2 SPNS lysolipid transporter 2, sphingosine-1-phosphate IAGP MGI PMID:22406534 NCBI chr11:72,342,464...72,380,797
Ensembl chr11:72,342,464...72,380,730
JBrowse link
G Syk spleen tyrosine kinase IAGP MGI PMID:22728826 NCBI chr13:52,736,670...52,802,828
Ensembl chr13:52,737,209...52,802,828
JBrowse link
decreased transitional stage T2 B cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam10 a disintegrin and metallopeptidase domain 10 IAGP MGI PMID:20156974 NCBI chr 9:70,586,133...70,687,511
Ensembl chr 9:70,586,279...70,687,511
JBrowse link
G Akap13 A kinase anchor protein 13 IAGP MGI PMID:19211510 NCBI chr 7:75,105,271...75,404,357
Ensembl chr 7:75,105,282...75,404,357
JBrowse link
G Arid3a AT-rich interaction domain 3A IAGP MGI PMID:21199920 NCBI chr10:79,762,877...79,790,852
Ensembl chr10:79,762,877...79,790,852
JBrowse link
G Arpc1b actin related protein 2/3 complex, subunit 1B IEA MGI NCBI chr 5:145,051,066...145,064,996
Ensembl chr 5:145,051,025...145,067,515
JBrowse link
G Atp11c ATPase, class VI, type 11C IAGP MGI PMID:21423172 NCBI chr  X:59,268,643...59,450,041
Ensembl chr  X:59,268,650...59,636,304
JBrowse link
G Bcl3 B cell leukemia/lymphoma 3 IAGP MGI PMID:24244019 NCBI chr 7:19,542,387...19,556,691
Ensembl chr 7:19,542,387...19,556,695
JBrowse link
G Cd19 CD19 antigen IAGP MGI PMID:20156974 PMID:21795747 PMID:25238757 NCBI chr 7:126,007,620...126,016,401
Ensembl chr 7:126,007,622...126,014,061
JBrowse link
G Cd22 CD22 antigen IAGP MGI PMID:22965838 NCBI chr 7:30,564,829...30,579,767
Ensembl chr 7:30,564,827...30,579,767
JBrowse link
G Cd79a CD79A antigen (immunoglobulin-associated alpha) IAGP MGI PMID:21427701 PMID:21708930 NCBI chr 7:24,596,922...24,601,283
Ensembl chr 7:24,596,806...24,601,622
JBrowse link
G Cog6 component of oligomeric golgi complex 6 IEA MGI NCBI chr 3:52,889,544...52,924,644
Ensembl chr 3:52,889,296...52,924,658
JBrowse link
G Commd10 COMM domain containing 10 IAGP MGI PMID:25057009 NCBI chr18:47,091,917...47,242,435
Ensembl chr18:47,091,883...47,367,351
JBrowse link
G Ell2 elongation factor for RNA polymerase II 2 IAGP MGI PMID:25238757 NCBI chr13:75,855,603...75,920,480
Ensembl chr13:75,854,876...75,920,483
JBrowse link
G Gimap1 GTPase, IMAP family member 1 IAGP MGI PMID:20194894 NCBI chr 6:48,715,981...48,720,729
Ensembl chr 6:48,715,988...48,720,729
JBrowse link
G Gmds GDP-mannose 4, 6-dehydratase IEA MGI NCBI chr13:32,003,566...32,522,744
Ensembl chr13:32,003,562...32,522,723
JBrowse link
G Grb2 growth factor receptor bound protein 2 IAGP MGI PMID:21427701 NCBI chr11:115,534,871...115,599,423
Ensembl chr11:115,534,871...115,599,423
JBrowse link
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano IAGP MGI PMID:21795747 NCBI chr 6:113,044,389...113,054,205
Ensembl chr 6:113,043,843...113,055,336
JBrowse link
G Hax1 HCLS1 associated X-1 IAGP MGI PMID:20865787 NCBI chr 3:89,902,753...89,906,023
Ensembl chr 3:89,902,753...89,906,087
JBrowse link
G Igh immunoglobulin heavy chain complex IAGP MGI PMID:21623346 NCBI chr12:113,222,388...115,973,574 JBrowse link
G Igk immunoglobulin kappa chain complex IAGP MGI PMID:11869685 NCBI chr 6:67,532,620...70,703,738 JBrowse link
G Iglc1 immunoglobulin lambda constant 1 IAGP MGI PMID:11869685 NCBI chr16:18,880,502...18,880,821
Ensembl chr16:18,880,368...18,880,821
JBrowse link
G Kdelr1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 IAGP MGI PMID:26438836 NCBI chr 7:45,522,264...45,533,150
Ensembl chr 7:45,522,196...45,533,156
JBrowse link
G Lama5 laminin, alpha 5 IAGP MGI PMID:23847204 NCBI chr 2:179,818,166...179,867,652
Ensembl chr 2:179,818,166...179,867,652
JBrowse link
G Map3k14 mitogen-activated protein kinase kinase kinase 14 IAGP MGI PMID:26116508 NCBI chr11:103,110,590...103,158,227
Ensembl chr11:103,110,588...103,158,298
JBrowse link
G Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100 IAGP MGI PMID:12391023 NCBI chr19:46,285,478...46,300,839
Ensembl chr19:46,292,759...46,300,824
JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha IAGP MGI PMID:21333553 NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432
JBrowse link
G Sh3kbp1 SH3-domain kinase binding protein 1 IAGP MGI PMID:21708930 NCBI chr  X:158,409,888...158,758,916
Ensembl chr  X:158,410,268...158,761,065
JBrowse link
G Son Son DNA binding protein IAGP MGI PMID:38290089 NCBI chr16:91,444,712...91,476,080
Ensembl chr16:91,444,394...91,476,109
JBrowse link
G Sppl2a signal peptide peptidase like 2A IAGP MGI PMID:23267013 PMID:23267015 PMID:23267016 NCBI chr 2:126,732,311...126,775,706
Ensembl chr 2:126,732,311...126,775,155
JBrowse link
G Syk spleen tyrosine kinase IAGP MGI PMID:22728826 NCBI chr13:52,736,670...52,802,828
Ensembl chr13:52,737,209...52,802,828
JBrowse link
G Vav1 vav 1 oncogene IAGP MGI PMID:14623913 NCBI chr17:57,586,080...57,636,236
Ensembl chr17:57,586,100...57,635,031
JBrowse link
G Vav2 vav 2 oncogene IAGP MGI PMID:14623913 NCBI chr 2:27,152,116...27,317,620
Ensembl chr 2:27,152,116...27,317,045
JBrowse link
G Vav3 vav 3 oncogene IAGP MGI PMID:14623913 NCBI chr 3:109,247,757...109,593,010
Ensembl chr 3:109,247,969...109,593,014
JBrowse link
G Zfp318 zinc finger protein 318 IAGP MGI PMID:25057009 NCBI chr17:46,694,444...46,731,846
Ensembl chr17:46,694,657...46,731,846
JBrowse link
decreased transitional stage T3 B cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp11c ATPase, class VI, type 11C IAGP MGI PMID:21423172 NCBI chr  X:59,268,643...59,450,041
Ensembl chr  X:59,268,650...59,636,304
JBrowse link
G Card11 caspase recruitment domain family, member 11 IAGP MGI PMID:31784498 NCBI chr 5:140,858,109...140,986,398
Ensembl chr 5:140,858,745...140,986,337
JBrowse link
G Cd19 CD19 antigen IAGP MGI PMID:25238757 NCBI chr 7:126,007,620...126,016,401
Ensembl chr 7:126,007,622...126,014,061
JBrowse link
G Cd79a CD79A antigen (immunoglobulin-associated alpha) IAGP MGI PMID:21708930 NCBI chr 7:24,596,922...24,601,283
Ensembl chr 7:24,596,806...24,601,622
JBrowse link
G Ell2 elongation factor for RNA polymerase II 2 IAGP MGI PMID:25238757 NCBI chr13:75,855,603...75,920,480
Ensembl chr13:75,854,876...75,920,483
JBrowse link
G Sh3kbp1 SH3-domain kinase binding protein 1 IAGP MGI PMID:21708930 NCBI chr  X:158,409,888...158,758,916
Ensembl chr  X:158,410,268...158,761,065
JBrowse link
G Sppl2a signal peptide peptidase like 2A IAGP MGI PMID:23267016 NCBI chr 2:126,732,311...126,775,706
Ensembl chr 2:126,732,311...126,775,155
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 17088
    immune system phenotype 5777
      abnormal immune system morphology 4142
        abnormal immune system development 917
          abnormal leukopoiesis 875
            abnormal lymphopoiesis 752
              abnormal B cell differentiation 401
                abnormal immature B cell morphology 196
                  abnormal transitional stage B cell morphology 104
                    decreased transitional stage B cell number 78
                      absent transitional stage B cells 1
                      decreased transitional stage T1 B cell number + 22
                      decreased transitional stage T2 B cell number + 33
                      decreased transitional stage T3 B cell number + 7
Path 2
Term Annotations click to browse term
  mammalian phenotype 17088
    hematopoietic system phenotype 5611
      abnormal hematopoietic system morphology/development 5137
        abnormal hematopoietic cell morphology 4314
          abnormal blood cell morphology 3215
            abnormal hemopoiesis 1163
              abnormal definitive hematopoiesis 1136
                abnormal leukopoiesis 875
                  abnormal lymphopoiesis 752
                    abnormal B cell differentiation 401
                      abnormal immature B cell morphology 196
                        abnormal immature B cell number 188
                          decreased immature B cell number 149
                            decreased transitional stage B cell number 78
                              absent transitional stage B cells 1
                              decreased transitional stage T1 B cell number + 22
                              decreased transitional stage T2 B cell number + 33
                              decreased transitional stage T3 B cell number + 7
paths to the root