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Gene: Traf3ip2 (TRAF3 interacting protein 2) Mus musculus
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Symbol: Traf3ip2
Name: TRAF3 interacting protein 2
Description: Exhibits signaling receptor binding activity. Involved in B cell apoptotic process; humoral immune response; and immunoglobulin secretion. Used to study Sjogren's syndrome; atopic dermatitis; and systemic lupus erythematosus. Human ortholog(s) of this gene implicated in chronic mucocutaneous candidiasis and psoriasis 13. Orthologous to human TRAF3IP2 (TRAF3 interacting protein 2); INTERACTS WITH 2-butoxyethanol; 4-hydroxynon-2-enal; 4-hydroxyphenyl retinamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Act1; adapter protein CIKS; AI429613; CIKS
Orthologs:
Homo sapiens (human) : TRAF3IP2 (TRAF3 interacting protein 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Traf3ip2 (Traf3 interacting protein 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Traf3ip2 (TRAF3 interacting protein 2)
Pan paniscus (bonobo/pygmy chimpanzee) : TRAF3IP2 (TRAF3 interacting protein 2)
Canis lupus familiaris (dog) : TRAF3IP2 (TRAF3 interacting protein 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Traf3ip2 (TRAF3 interacting protein 2)
Sus scrofa (pig) : TRAF3IP2 (TRAF3 interacting protein 2)
more info ...
Related Pseudogenes: Gm15741   Gm18400  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
NCBI Annotation Information: Note: Act1 (Gene ID:109776) and Traf3ip2 (Gene ID:103213) share the Act1 symbol/alias in common. Act1 is a widely used alternative name for adapter protein CIKS (Traf3ip2), which can be confused with the official symbol for Act1, actin related gene 1 (Act1). [15 Oct 2019]
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm381039,612,934 - 39,655,307 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371039,332,740 - 39,375,113 (+)NCBIGRCm37mm9NCBIm37
MGSCv361039,302,350 - 39,344,723 (+)NCBImm8
Celera1040,498,927 - 40,541,335 (+)NCBICelera
Cytogenetic Map10 B1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Traf3ip2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1312404
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-10-22
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.