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Gene: Traf3ip2 (TRAF3 interacting protein 2) Mus musculus
Symbol: Traf3ip2
Name: TRAF3 interacting protein 2
Description: Exhibits signaling receptor binding activity. Involved in B cell apoptotic process; humoral immune response; and immunoglobulin secretion. Used to study Sjogren's syndrome; atopic dermatitis; and systemic lupus erythematosus. Human ortholog(s) of this gene implicated in chronic mucocutaneous candidiasis and psoriasis 13. Orthologous to human TRAF3IP2 (TRAF3 interacting protein 2); INTERACTS WITH 2-butoxyethanol; 4-hydroxynon-2-enal; 4-hydroxyphenyl retinamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Act1; adapter protein CIKS; AI429613; CIKS
Homo sapiens (human) : TRAF3IP2 (TRAF3 interacting protein 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Traf3ip2 (Traf3 interacting protein 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Traf3ip2 (TRAF3 interacting protein 2)
Pan paniscus (bonobo/pygmy chimpanzee) : TRAF3IP2 (TRAF3 interacting protein 2)
Canis lupus familiaris (dog) : TRAF3IP2 (TRAF3 interacting protein 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Traf3ip2 (TRAF3 interacting protein 2)
Sus scrofa (pig) : TRAF3IP2 (TRAF3 interacting protein 2)
more info ...
Related Pseudogenes: Gm15741   Gm18400  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
NCBI Annotation Information: Note: Act1 (Gene ID:109776) and Traf3ip2 (Gene ID:103213) share the Act1 symbol/alias in common. Act1 is a widely used alternative name for adapter protein CIKS (Traf3ip2), which can be confused with the official symbol for Act1, actin related gene 1 (Act1). [15 Oct 2019]
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm381039,612,934 - 39,655,307 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371039,332,740 - 39,375,113 (+)NCBIGRCm37mm9NCBIm37
MGSCv361039,302,350 - 39,344,723 (+)NCBImm8
Celera1040,498,927 - 40,541,335 (+)NCBICelera
Cytogenetic Map10 B1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Traf3ip2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1312404
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-10-22
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.