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ONTOLOGY REPORT - ANNOTATIONS

Term:prostate gland epithelium morphogenesis
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Accession:GO:0060740 term browser browse the term
Definition:The process in which the anatomical structures of epithelia of the prostate gland are generated and organized. An epithelium consists of closely packed cells arranged in one or more layers, that covers the outer surfaces of the body or lines any internal cavity or tube.

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prostate gland epithelium morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor IEA
ISO		 GO_REF:0000107
MGI:2385927|MGI:2451025 (MGI:3718266|PMID:17652515)		 Ensembl
RGD		 PMID:17652515 GO_REF:0000107 MGI:3718266 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026 		JBrowse link
G Cyp7b1 cytochrome P450 family 7 subfamily B member 1 IEA
ISO		 GO_REF:0000107
MGI:2182328 (MGI:3761900|PMID:12370428)		 Ensembl
RGD		 PMID:12370428 GO_REF:0000107 MGI:3761900 NCBI chr 2:102,701,903...102,871,257
Ensembl chr 2:102,701,903...102,871,257 		JBrowse link
G Esr2 estrogen receptor 2 ISO MGI:2152217 (MGI:3047056|PMID:15187231), (MGI:3761900|PMID:12370428) RGD PMID:12370428 PMID:15187231 MGI:3047056 MGI:3761900 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251 		JBrowse link
G Foxa1 forkhead box A1 IEA
ISO		 GO_REF:0000107
MGI:2384404 (MGI:3603077|PMID:15987773)		 Ensembl
RGD		 PMID:15987773 GO_REF:0000107 MGI:3603077 NCBI chr 6:78,516,579...78,549,669
Ensembl chr 6:78,545,804...78,549,669 		JBrowse link
G Id4 inhibitor of DNA binding 4, HLH protein ISO MGI:3505549 (MGI:5559786|PMID:23786676) RGD PMID:23786676 MGI:5559786 NCBI chr17:16,692,557...16,695,126
Ensembl chr17:16,692,557...16,695,126 		JBrowse link
G Igf1 insulin-like growth factor 1 ISO MGI:1857466 (MGI:3769830|PMID:17138659) RGD PMID:17138659 MGI:3769830 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609 		JBrowse link
G Igf1r insulin-like growth factor 1 receptor ISO MGI:2386328 (MGI:3789406|PMID:18451178) RGD PMID:18451178 MGI:3789406 NCBI chr 1:128,924,921...129,213,816
Ensembl chr 1:128,924,966...129,206,516 		JBrowse link
G Mmp2 matrix metallopeptidase 2 IMP RGD PMID:20108352 RGD:2325693 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611 		JBrowse link
G Notch1 notch receptor 1 ISO MGI:1933835 (MGI:3612808|PMID:16360140) RGD PMID:16360140 MGI:3612808 NCBI chr 3:3,905,562...3,951,015
Ensembl chr 3:3,905,453...3,951,025 		JBrowse link
G Rarg retinoic acid receptor, gamma ISO MGI:1931079 (MGI:60925|PMID:8388780) RGD PMID:8388780 MGI:60925 NCBI chr 7:143,840,739...143,863,206
Ensembl chr 7:143,839,980...143,863,186 		JBrowse link
G Stat5a signal transducer and activator of transcription 5A ISO MGI:1857249 (MGI:1861068|PMID:10908145) RGD PMID:10908145 MGI:1861068 NCBI chr10:88,764,732...88,789,060
Ensembl chr10:88,764,732...88,789,057 		JBrowse link
G Tnc tenascin C ISO MGI:2148540 (MGI:3832136|PMID:18950615) RGD PMID:18950615 MGI:3832136 NCBI chr 5:79,789,686...79,874,555
Ensembl chr 5:79,789,671...79,874,671 		JBrowse link
activation of prostate induction by androgen receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor IEA
ISO		 GO_REF:0000107
MGI:3716756 (MGI:3714080|PMID:17317769)		 Ensembl
RGD		 PMID:17317769 GO_REF:0000107 MGI:3714080 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026 		JBrowse link
branching involved in prostate gland morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 IEA
ISO		 GO_REF:0000107
MGI:1857137 (MGI:1934513|PMID:11401393)		 Ensembl
RGD		 PMID:11401393 GO_REF:0000107 MGI:1934513 NCBI chr15:20,776,060...20,791,013
Ensembl chr15:20,776,054...20,822,740 		JBrowse link
G Cd44 CD44 molecule (Indian blood group) ISO (MGI:1098910|PMID:9374396) RGD PMID:9374396 MGI:1098910 NCBI chr 3:92,695,083...92,783,820
Ensembl chr 3:92,696,313...92,783,658 		JBrowse link
G Fem1b fem-1 homolog B ISO MGI:3811024 (MGI:3809320|PMID:18816836) RGD PMID:18816836 MGI:3809320 NCBI chr 8:67,695,041...67,708,313
Ensembl chr 8:67,694,904...67,708,304 		JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 ISO MGI:1856633|MGI:3044679 (MGI:2655013|PMID:12666202), (MGI:3703455|PMID:17215304), (MGI:3703479|PMID:17202188) RGD PMID:12666202 PMID:17202188 PMID:17215304 MGI:2655013 MGI:3703455 MGI:3703479 NCBI chr 1:200,590,951...200,696,946
Ensembl chr 1:200,590,953...200,696,928 		JBrowse link
G Hoxa13 homeo box A13 ISO MGI:1857336 (MGI:1336094|PMID:10210434) RGD PMID:10210434 MGI:1336094 Ensembl chr 4:82,228,017...82,229,397 JBrowse link
G Nkx3-1 NK3 homeobox 1 ISS
ISO		 GO_REF:0000024
MGI:1926960|MGI:1928654|MGI:1928655 (MGI:1335939|PMID:10215624), (MGI:1861552|PMID:10906459), (MGI:1891543|PMID:11002344)		 UniProt
RGD		 PMID:10215624 PMID:10906459 PMID:11002344 GO_REF:0000024 MGI:1335939 MGI:1861552 MGI:1891543 NCBI chr15:51,065,316...51,067,908
Ensembl chr15:51,065,316...51,068,421 		JBrowse link
G Shh sonic hedgehog signaling molecule ISO (MGI:1335656|PMID:10208740) RGD PMID:10208740 MGI:1335656 NCBI chr 4:718,538...727,691
Ensembl chr 4:718,538...727,691 		JBrowse link
epithelial cell proliferation involved in prostatic bud elongation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sox9 SRY-box transcription factor 9 ISS
ISO		 GO_REF:0000024
MGI:2429649|MGI:3689997 (MGI:3794471|PMID:18325490)		 UniProt
RGD		 PMID:18325490 GO_REF:0000024 MGI:3794471 NCBI chr10:101,288,528...101,294,030
Ensembl chr10:101,288,489...101,293,379 		JBrowse link
negative regulation of prostatic bud formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 IEA
ISO		 GO_REF:0000107
MGI:1857137 (MGI:1934513|PMID:11401393), (MGI:3785350|PMID:18393306)		 Ensembl
RGD		 PMID:11401393 PMID:18393306 GO_REF:0000107 MGI:1934513 MGI:3785350 NCBI chr15:20,776,060...20,791,013
Ensembl chr15:20,776,054...20,822,740 		JBrowse link
G Bmp7 bone morphogenetic protein 7 ISO (MGI:3612905|PMID:16324690) RGD PMID:16324690 MGI:3612905 NCBI chr 3:170,879,972...170,955,820
Ensembl chr 3:170,879,973...170,955,399 		JBrowse link
G Sulf1 sulfatase 1 IEA
ISO
ISS		 GO_REF:0000107
(MGI:4941125|PMID:20410206)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:20410206 GO_REF:0000024 GO_REF:0000107 MGI:4941125 NCBI chr 5:5,999,520...6,186,901
Ensembl chr 5:5,999,475...6,186,329 		JBrowse link
G Wnt5a Wnt family member 5A IEA
ISO		 GO_REF:0000107
MGI:1857617 (MGI:3822053|PMID:18804104)		 Ensembl
RGD		 PMID:18804104 GO_REF:0000107 MGI:3822053 NCBI chr16:4,469,451...4,490,271
Ensembl chr16:4,469,468...4,489,860 		JBrowse link
primary prostatic bud elongation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Shh sonic hedgehog signaling molecule IEA
ISO		 GO_REF:0000107
(MGI:1335656|PMID:10208740)		 Ensembl
RGD		 PMID:10208740 GO_REF:0000107 MGI:1335656 NCBI chr 4:718,538...727,691
Ensembl chr 4:718,538...727,691 		JBrowse link
prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Esr1 estrogen receptor 1 IEA
ISO		 GO_REF:0000107
MGI:2150897 (MGI:3834820|PMID:18535112)		 Ensembl
RGD		 PMID:18535112 GO_REF:0000107 MGI:3834820 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796 		JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 ISO MGI:3044679 (MGI:3703455|PMID:17215304) RGD PMID:17215304 MGI:3703455 NCBI chr 1:200,590,951...200,696,946
Ensembl chr 1:200,590,953...200,696,928 		JBrowse link
G Frs2 fibroblast growth factor receptor substrate 2 ISO MGI:3689997|MGI:3768912 (MGI:3772963|PMID:18184727) RGD PMID:18184727 MGI:3772963 NCBI chr 7:60,128,506...60,210,482
Ensembl chr 7:60,128,508...60,210,518 		JBrowse link
G Hoxb13 homeo box B13 ISO MGI:96205 (MGI:2653060|PMID:12620974) RGD PMID:12620974 MGI:2653060 NCBI chr10:84,031,955...84,034,228
Ensembl chr10:84,031,955...84,034,228 		JBrowse link
G Hoxd13 homeo box D13 ISO MGI:107730 (MGI:2653645|PMID:12668621) RGD PMID:12668621 MGI:2653645 NCBI chr 3:61,590,376...61,593,692
Ensembl chr 3:61,590,376...61,593,692 		JBrowse link
G Igf1 insulin-like growth factor 1 ISO MGI:1857466 (MGI:1336377|PMID:10218945) RGD PMID:10218945 MGI:1336377 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609 		JBrowse link
G Sfrp1 secreted frizzled-related protein 1 IEA
ISO		 GO_REF:0000107
MGI:3796251 (MGI:3795332|PMID:18371946)		 Ensembl
RGD		 PMID:18371946 GO_REF:0000107 MGI:3795332 NCBI chr16:73,372,007...73,410,777
Ensembl chr16:73,372,007...73,410,777 		JBrowse link
prostate epithelial cord elongation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Esr1 estrogen receptor 1 IEA
ISO		 GO_REF:0000107
MGI:2150897 (MGI:3834820|PMID:18535112)		 Ensembl
RGD		 PMID:18535112 GO_REF:0000107 MGI:3834820 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796 		JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 ISO MGI:3044679 (MGI:3703455|PMID:17215304) RGD PMID:17215304 MGI:3703455 NCBI chr 1:200,590,951...200,696,946
Ensembl chr 1:200,590,953...200,696,928 		JBrowse link
G Shh sonic hedgehog signaling molecule IEA
ISO		 GO_REF:0000107
(MGI:3037217|PMID:15013801)		 Ensembl
RGD		 PMID:15013801 GO_REF:0000107 MGI:3037217 NCBI chr 4:718,538...727,691
Ensembl chr 4:718,538...727,691 		JBrowse link
prostatic bud formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgf10 fibroblast growth factor 10 ISO MGI:88064 (MGI:2673763|PMID:12941620) RGD PMID:12941620 MGI:2673763 NCBI chr 2:51,673,480...51,747,533
Ensembl chr 2:51,672,722...51,750,369 		JBrowse link
G Gli2 GLI family zinc finger 2 ISO MGI:1857509 (MGI:3832153|PMID:16707121) RGD PMID:16707121 MGI:3832153 NCBI chr13:34,829,021...35,049,172
Ensembl chr13:34,829,139...35,048,444 		JBrowse link
G Nog noggin IEA
ISO		 GO_REF:0000107
MGI:1862000 (MGI:3771245|PMID:18028901)		 Ensembl
RGD		 PMID:18028901 GO_REF:0000107 MGI:3771245 NCBI chr10:76,811,759...76,813,386
Ensembl chr10:76,811,759...76,813,386 		JBrowse link
G Shh sonic hedgehog signaling molecule NOT ISO MGI:88064 (MGI:3037217|PMID:15013801) RGD PMID:15013801 MGI:3037217 NCBI chr 4:718,538...727,691
Ensembl chr 4:718,538...727,691 		JBrowse link
G Tp63 tumor protein p63 ISO MGI:1934269 (MGI:1928010|PMID:11106548) RGD PMID:11106548 MGI:1928010 NCBI chr11:78,234,853...78,456,559
Ensembl chr11:78,234,800...78,456,501 		JBrowse link
regulation of branching involved in prostate gland morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 IEA
ISO		 GO_REF:0000107
MGI:2158495 (MGI:3575593|PMID:15772937)		 Ensembl
RGD		 PMID:15772937 GO_REF:0000107 MGI:3575593 NCBI chr15:20,776,060...20,791,013
Ensembl chr15:20,776,054...20,822,740 		JBrowse link
G Bmp7 bone morphogenetic protein 7 ISO MGI:2136986 (MGI:3612905|PMID:16324690) RGD PMID:16324690 MGI:3612905 NCBI chr 3:170,879,972...170,955,820
Ensembl chr 3:170,879,973...170,955,399 		JBrowse link
G Esr1 estrogen receptor 1 IEA
ISO		 GO_REF:0000107
MGI:2150897 (MGI:3529408|PMID:15665095), (MGI:3839071|PMID:18755802)		 Ensembl
RGD		 PMID:15665095 PMID:18755802 GO_REF:0000107 MGI:3529408 MGI:3839071 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796 		JBrowse link
G Hoxd13 homeo box D13 ISO MGI:1857871 (MGI:86772|PMID:9097018) RGD PMID:9097018 MGI:86772 NCBI chr 3:61,590,376...61,593,692
Ensembl chr 3:61,590,376...61,593,692 		JBrowse link
G Rxra retinoid X receptor alpha ISO MGI:2385918 (MGI:2385387|PMID:12183441) RGD PMID:12183441 MGI:2385387 NCBI chr 3:6,272,560...6,295,354
Ensembl chr 3:6,211,789...6,295,908 		JBrowse link
G Sfrp1 secreted frizzled-related protein 1 IEA
ISO		 GO_REF:0000107
MGI:3796251 (MGI:3795332|PMID:18371946)		 Ensembl
RGD		 PMID:18371946 GO_REF:0000107 MGI:3795332 NCBI chr16:73,372,007...73,410,777
Ensembl chr16:73,372,007...73,410,777 		JBrowse link
regulation of prostatic bud formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor ISO MGI:1099809 (MGI:2673763|PMID:12941620) RGD PMID:12941620 MGI:2673763 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026 		JBrowse link
G Shh sonic hedgehog signaling molecule IEA
ISO		 GO_REF:0000107
(MGI:2386799|PMID:12221011), (MGI:3785350|PMID:18393306)		 Ensembl
RGD		 PMID:12221011 PMID:18393306 GO_REF:0000107 MGI:2386799 MGI:3785350 NCBI chr 4:718,538...727,691
Ensembl chr 4:718,538...727,691 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20045
    reproductive process 1799
      developmental process involved in reproduction 1189
        prostate gland epithelium morphogenesis 33
          branching involved in prostate gland morphogenesis + 15
          primary prostatic bud elongation + 2
          prostate epithelial cord elongation 3
          prostate glandular acinus morphogenesis + 7
          prostatic bud formation + 10
Path 2
Term Annotations click to browse term
  biological_process 20045
    developmental process 6824
      anatomical structure development 6290
        multicellular organism development 5766
          system development 5298
            animal organ development 4055
              gland development 665
                prostate gland development 63
                  prostate gland morphogenesis 35
                    prostate gland epithelium morphogenesis 33
                      branching involved in prostate gland morphogenesis + 15
                      primary prostatic bud elongation + 2
                      prostate epithelial cord elongation 3
                      prostate glandular acinus morphogenesis + 7
                      prostatic bud formation + 10
paths to the root