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ONTOLOGY REPORT - ANNOTATIONS

Term:prostate gland epithelium morphogenesis
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Accession:GO:0060740 term browser browse the term
Definition:The process in which the anatomical structures of epithelia of the prostate gland are generated and organized. An epithelium consists of closely packed cells arranged in one or more layers, that covers the outer surfaces of the body or lines any internal cavity or tube.


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prostate gland epithelium morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor acts_upstream_of_or_within ISO
IEA 		MGI:2385927|MGI:2451025 (PMID:17652515)
GO_REF:0000107 		RGD
Ensembl		 PMID:17652515 GO_REF:0000107 NCBI chr  X:67,135,317...67,304,476
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Cyp7b1 cytochrome P450 family 7 subfamily B member 1 acts_upstream_of_or_within ISO
IEA 		MGI:2182328 (PMID:12370428)
GO_REF:0000107 		RGD
Ensembl		 PMID:12370428 GO_REF:0000107 NCBI chr 2:100,502,791...100,669,713
Ensembl chr 2:100,502,791...100,669,698 		JBrowse link
G Esr2 estrogen receptor 2 acts_upstream_of_or_within ISO MGI:2152217 (PMID:12370428), (PMID:15187231) RGD PMID:12370428 PMID:15187231 NCBI chr 6:100,589,553...100,645,240
Ensembl chr 6:94,809,547...94,908,919 		JBrowse link
G Foxa1 forkhead box A1 acts_upstream_of_or_within ISO
IEA 		MGI:2384404 (PMID:15987773)
GO_REF:0000107 		RGD
Ensembl		 PMID:15987773 GO_REF:0000107 NCBI chr 6:75,099,907...75,136,534
Ensembl chr 6:75,103,503...75,136,188 		JBrowse link
G Id4 inhibitor of DNA binding 4 acts_upstream_of_or_within ISO MGI:3505549 (PMID:23786676) RGD PMID:23786676 NCBI chr17:16,595,724...16,598,293
Ensembl chr17:16,389,387...16,392,470 		JBrowse link
G Igf1 insulin-like growth factor 1 acts_upstream_of_or_within ISO MGI:1857466 (PMID:17138659) RGD PMID:17138659 NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Igf1r insulin-like growth factor 1 receptor acts_upstream_of_or_within ISO MGI:2386328 (PMID:18451178) RGD PMID:18451178 NCBI chr 1:130,959,787...131,248,664
Ensembl chr 1:121,550,743...121,831,777 		JBrowse link
G Mmp2 matrix metallopeptidase 2 IMP RGD PMID:20108352 RGD:2325693 NCBI chr19:30,327,643...30,355,856
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Notch1 notch receptor 1 acts_upstream_of_or_within ISO
IEA 		MGI:1933835 (PMID:16360140)
GO_REF:0000107 		RGD
Ensembl		 PMID:16360140 GO_REF:0000107 NCBI chr 3:29,676,040...29,721,613
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
G Rarg retinoic acid receptor, gamma acts_upstream_of_or_within ISO
IEA 		MGI:1931079 (PMID:8388780)
GO_REF:0000107 		RGD
Ensembl		 PMID:8388780 GO_REF:0000107 NCBI chr 7:133,367,833...133,390,301
Ensembl chr 7:133,367,833...133,390,177 		JBrowse link
G Stat5a signal transducer and activator of transcription 5A acts_upstream_of_or_within ISO
IEA 		MGI:1857249 (PMID:10908145)
GO_REF:0000107 		RGD
Ensembl		 PMID:10908145 GO_REF:0000107 NCBI chr10:86,285,859...86,310,187
Ensembl chr10:85,785,537...85,809,866 		JBrowse link
G Tnc tenascin C acts_upstream_of_or_within ISO
IEA 		MGI:2148540 (PMID:18950615)
GO_REF:0000107 		RGD
Ensembl		 PMID:18950615 GO_REF:0000107 NCBI chr 5:77,375,851...77,460,712
Ensembl chr 5:77,375,851...77,460,624 		JBrowse link
branching involved in prostate gland morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 acts_upstream_of_or_within ISO
IEA 		MGI:1857137 (PMID:11401393)
GO_REF:0000107 		RGD
Ensembl		 PMID:11401393 GO_REF:0000107 NCBI chr15:22,098,191...22,113,145
Ensembl chr15:19,618,542...19,623,306 		JBrowse link
G Cd44 CD44 molecule acts_upstream_of_or_within ISO (PMID:9374396) RGD PMID:9374396 NCBI chr 3:109,610,824...109,699,776
Ensembl chr 3:89,157,058...89,244,620 		JBrowse link
G Fem1b fem-1 homolog B acts_upstream_of_or_within ISO
IEA 		MGI:3811024 (PMID:18816836)
GO_REF:0000107 		RGD
Ensembl		 PMID:18816836 GO_REF:0000107 NCBI chr 8:63,265,301...63,278,577
Ensembl chr 8:63,265,301...63,278,577 		JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 acts_upstream_of_or_within ISO MGI:1856633|MGI:3044679 (PMID:12666202), (PMID:17202188), (PMID:17215304) RGD PMID:12666202 PMID:17202188 PMID:17215304 NCBI chr 1:194,175,703...194,280,914
Ensembl chr 1:184,745,420...184,850,626 		JBrowse link
G Hoxa13 homeo box A13 acts_upstream_of_or_within ISO
IEA 		MGI:1857336 (PMID:10210434)
GO_REF:0000107 		RGD
Ensembl		 PMID:10210434 GO_REF:0000107 NCBI chr 4:82,689,566...82,691,701
Ensembl chr 4:81,358,956...81,361,091 		JBrowse link
G Nkx3-1 NK3 homeobox 1 acts_upstream_of_or_within
involved_in 		ISO
ISS 		MGI:1926960|MGI:1928654|MGI:1928655 (PMID:10215624), (PMID:10906459), (PMID:11002344)
GO_REF:0000024 		RGD
UniProt		 PMID:10215624 PMID:10906459 PMID:11002344 GO_REF:0000024 NCBI chr15:50,883,661...50,886,253
Ensembl chr15:44,473,851...44,476,441 		JBrowse link
G Shh sonic hedgehog signaling molecule acts_upstream_of_or_within ISO
IEA 		(PMID:10208740)
GO_REF:0000107 		RGD
Ensembl		 PMID:10208740 GO_REF:0000107 NCBI chr 4:7,687,872...7,697,025
Ensembl chr 4:6,954,017...6,963,170 		JBrowse link
epithelial cell proliferation involved in prostatic bud elongation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sox9 SRY-box transcription factor 9 involved_in
acts_upstream_of_or_within 		ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
MGI:2429649|MGI:3689997 (PMID:18325490) 		UniProt
Ensembl
RGD		 PMID:18325490 GO_REF:0000024 GO_REF:0000107 NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994 		JBrowse link
negative regulation of prostatic bud formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 acts_upstream_of_or_within ISO
IEA 		MGI:1857137 (PMID:11401393), (PMID:18393306)
GO_REF:0000107 		RGD
Ensembl		 PMID:11401393 PMID:18393306 GO_REF:0000107 NCBI chr15:22,098,191...22,113,145
Ensembl chr15:19,618,542...19,623,306 		JBrowse link
G Bmp7 bone morphogenetic protein 7 acts_upstream_of_or_within ISO
IEA 		(PMID:16324690)
GO_REF:0000107 		RGD
Ensembl		 PMID:16324690 GO_REF:0000107 NCBI chr 3:182,059,318...182,135,273
Ensembl chr 3:161,516,462...161,716,788 		JBrowse link
G Sulf1 sulfatase 1 involved_in ISS
ISO 		GO_REF:0000024
(PMID:20410206) 		UniProt
RGD		 PMID:20410206 GO_REF:0000024 NCBI chr 5:6,362,894...6,526,174
Ensembl chr 5:6,362,911...6,525,584 		JBrowse link
G Wnt5a Wnt family member 5A acts_upstream_of_or_within ISO
IEA 		MGI:1857617 (PMID:18804104)
GO_REF:0000107 		RGD
Ensembl		 PMID:18804104 GO_REF:0000107 NCBI chr16:3,702,300...3,724,860
Ensembl chr16:3,697,032...3,718,234 		JBrowse link
primary prostatic bud elongation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Shh sonic hedgehog signaling molecule acts_upstream_of_or_within ISO
IEA 		(PMID:10208740)
GO_REF:0000107 		RGD
Ensembl		 PMID:10208740 GO_REF:0000107 NCBI chr 4:7,687,872...7,697,025
Ensembl chr 4:6,954,017...6,963,170 		JBrowse link
prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Esr1 estrogen receptor 1 acts_upstream_of_or_within ISO
IEA 		MGI:2150897 (PMID:18535112)
GO_REF:0000107 		RGD
Ensembl		 PMID:18535112 GO_REF:0000107 NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 acts_upstream_of_or_within ISO MGI:3044679 (PMID:17215304) RGD PMID:17215304 NCBI chr 1:194,175,703...194,280,914
Ensembl chr 1:184,745,420...184,850,626 		JBrowse link
G Frs2 fibroblast growth factor receptor substrate 2 acts_upstream_of_or_within ISO
IEA 		MGI:3689997|MGI:3768912 (PMID:18184727)
GO_REF:0000107 		RGD
Ensembl		 PMID:18184727 GO_REF:0000107 NCBI chr 7:52,711,255...52,792,738
Ensembl chr 7:52,711,257...52,792,743 		JBrowse link
G Hoxb13 homeo box B13 acts_upstream_of_or_within ISO
IEA 		MGI:96205 (PMID:12620974)
GO_REF:0000107 		RGD
Ensembl		 PMID:12620974 GO_REF:0000107 NCBI chr10:81,160,498...81,162,777
Ensembl chr10:81,160,498...81,162,777 		JBrowse link
G Hoxd13 homeo box D13 acts_upstream_of_or_within ISO
IEA 		MGI:107730 (PMID:12668621)
GO_REF:0000107 		RGD
Ensembl		 PMID:12668621 GO_REF:0000107 NCBI chr 3:59,570,647...59,573,963
Ensembl chr 3:59,570,646...59,573,963 		JBrowse link
G Igf1 insulin-like growth factor 1 acts_upstream_of_or_within ISO MGI:1857466 (PMID:10218945) RGD PMID:10218945 NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Sfrp1 secreted frizzled-related protein 1 acts_upstream_of_or_within ISO
IEA 		MGI:3796251 (PMID:18371946)
GO_REF:0000107 		RGD
Ensembl		 PMID:18371946 GO_REF:0000107 NCBI chr16:75,278,325...75,316,736
Ensembl chr16:68,575,763...68,614,286 		JBrowse link
prostate epithelial cord elongation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Esr1 estrogen receptor 1 acts_upstream_of_or_within ISO
IEA 		MGI:2150897 (PMID:18535112)
GO_REF:0000107 		RGD
Ensembl		 PMID:18535112 GO_REF:0000107 NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 acts_upstream_of_or_within ISO MGI:3044679 (PMID:17215304) RGD PMID:17215304 NCBI chr 1:194,175,703...194,280,914
Ensembl chr 1:184,745,420...184,850,626 		JBrowse link
G Shh sonic hedgehog signaling molecule acts_upstream_of_or_within ISO
IEA 		(PMID:15013801)
GO_REF:0000107 		RGD
Ensembl		 PMID:15013801 GO_REF:0000107 NCBI chr 4:7,687,872...7,697,025
Ensembl chr 4:6,954,017...6,963,170 		JBrowse link
prostate induction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor acts_upstream_of_or_within ISO
IEA 		MGI:3716756 (PMID:17317769)
GO_REF:0000107 		RGD
Ensembl		 PMID:17317769 GO_REF:0000107 NCBI chr  X:67,135,317...67,304,476
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
prostatic bud formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 acts_upstream_of ISO
IEA 		MGI:1857137 (PMID:11401393)
GO_REF:0000107 		RGD
Ensembl		 PMID:11401393 GO_REF:0000107 NCBI chr15:22,098,191...22,113,145
Ensembl chr15:19,618,542...19,623,306 		JBrowse link
G Fgf10 fibroblast growth factor 10 acts_upstream_of_or_within ISO
IEA 		MGI:88064 (PMID:12941620)
GO_REF:0000107 		RGD
Ensembl		 PMID:12941620 GO_REF:0000107 NCBI chr 2:52,533,939...52,610,980
Ensembl chr 2:50,800,992...50,876,866 		JBrowse link
G Gli2 GLI family zinc finger 2 acts_upstream_of_or_within ISO MGI:1857509 (PMID:16707121) RGD PMID:16707121 NCBI chr13:32,499,678...32,716,418
Ensembl chr13:29,946,809...30,163,574 		JBrowse link
G Nog noggin acts_upstream_of_or_within ISO
IEA 		MGI:1862000 (PMID:18028901)
GO_REF:0000107 		RGD
Ensembl		 PMID:18028901 GO_REF:0000107 NCBI chr10:74,625,874...74,627,501
Ensembl chr10:74,128,712...74,130,339 		JBrowse link
G Shh sonic hedgehog signaling molecule NOT|acts_upstream_of_or_within ISO MGI:88064 (PMID:15013801) RGD PMID:15013801 NCBI chr 4:7,687,872...7,697,025
Ensembl chr 4:6,954,017...6,963,170 		JBrowse link
G Tp63 tumor protein p63 acts_upstream_of_or_within ISO
IEA 		MGI:1934269 (PMID:11106548)
GO_REF:0000107 		RGD
Ensembl		 PMID:11106548 GO_REF:0000107 NCBI chr11:88,343,647...88,554,543
Ensembl chr11:74,838,859...75,049,398 		JBrowse link
regulation of branching involved in prostate gland morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 acts_upstream_of_or_within ISO
IEA 		MGI:2158495 (PMID:15772937)
GO_REF:0000107 		RGD
Ensembl		 PMID:15772937 GO_REF:0000107 NCBI chr15:22,098,191...22,113,145
Ensembl chr15:19,618,542...19,623,306 		JBrowse link
G Bmp7 bone morphogenetic protein 7 acts_upstream_of_or_within ISO
IEA 		MGI:2136986 (PMID:16324690)
GO_REF:0000107 		RGD
Ensembl		 PMID:16324690 GO_REF:0000107 NCBI chr 3:182,059,318...182,135,273
Ensembl chr 3:161,516,462...161,716,788 		JBrowse link
G Esr1 estrogen receptor 1 acts_upstream_of_or_within ISO
IEA 		MGI:2150897 (PMID:15665095), (PMID:18755802)
GO_REF:0000107 		RGD
Ensembl		 PMID:15665095 PMID:18755802 GO_REF:0000107 NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Hoxd13 homeo box D13 acts_upstream_of_or_within ISO
IEA 		MGI:1857871 (PMID:9097018)
GO_REF:0000107 		RGD
Ensembl		 PMID:9097018 GO_REF:0000107 NCBI chr 3:59,570,647...59,573,963
Ensembl chr 3:59,570,646...59,573,963 		JBrowse link
G Rxra retinoid X receptor alpha acts_upstream_of_or_within ISO MGI:2385918 (PMID:12183441) RGD PMID:12183441 NCBI chr 3:31,387,892...31,474,415
Ensembl chr 3:10,989,832...11,073,712 		JBrowse link
G Sfrp1 secreted frizzled-related protein 1 acts_upstream_of_or_within ISO
IEA 		MGI:3796251 (PMID:18371946)
GO_REF:0000107 		RGD
Ensembl		 PMID:18371946 GO_REF:0000107 NCBI chr16:75,278,325...75,316,736
Ensembl chr16:68,575,763...68,614,286 		JBrowse link
regulation of prostatic bud formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor acts_upstream_of_or_within ISO
IEA 		MGI:1099809 (PMID:12941620)
GO_REF:0000107 		RGD
Ensembl		 PMID:12941620 GO_REF:0000107 NCBI chr  X:67,135,317...67,304,476
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Shh sonic hedgehog signaling molecule acts_upstream_of_or_within ISO
IEA 		(PMID:12221011), (PMID:18393306)
GO_REF:0000107 		RGD
Ensembl		 PMID:12221011 PMID:18393306 GO_REF:0000107 NCBI chr 4:7,687,872...7,697,025
Ensembl chr 4:6,954,017...6,963,170 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20543
    developmental process 7160
      developmental process involved in reproduction 1279
        prostate gland epithelium morphogenesis 33
          branching involved in prostate gland morphogenesis + 15
          primary prostatic bud elongation + 2
          prostate epithelial cord elongation 3
          prostate glandular acinus morphogenesis + 7
          prostatic bud formation + 10
Path 2
Term Annotations click to browse term
  biological_process 20543
    developmental process 7160
      anatomical structure development 6656
        multicellular organism development 5362
          system development 4644
            reproductive system development 453
              reproductive structure development 448
                prostate gland development 62
                  prostate gland morphogenesis 35
                    prostate gland epithelium morphogenesis 33
                      branching involved in prostate gland morphogenesis + 15
                      primary prostatic bud elongation + 2
                      prostate epithelial cord elongation 3
                      prostate glandular acinus morphogenesis + 7
                      prostatic bud formation + 10
paths to the root