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ONTOLOGY REPORT - ANNOTATIONS

Term:cellular hyperosmotic response
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Accession:GO:0071474 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hyperosmotic environment, i.e. an environment with a higher concentration of solutes than the organism or cell.
Synonyms:exact_synonym: cellular HOG response;   cellular hypertonic response;   cellular response to hypertonicity


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cellular hyperosmotic response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp1 aquaporin 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:11922632)		 UniProt
RGD		 PMID:11922632 GO_REF:0000024 NCBI chr 4:84,482,512...84,494,690
Ensembl chr 4:84,482,512...84,494,690 		JBrowse link
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 involved_in ISO (PMID:22711822) RGD PMID:22711822 NCBI chr 2:174,061,126...174,118,355
Ensembl chr 2:174,062,976...174,118,355 		JBrowse link
G Epo erythropoietin involved_in ISO (PMID:14569084) RGD PMID:14569084 NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946 		JBrowse link
G Errfi1 ERBB receptor feedback inhibitor 1 IEP RGD PMID:10749885 RGD:9685546 NCBI chr 5:161,323,981...161,337,289
Ensembl chr 5:161,323,998...161,337,282 		JBrowse link
G Mapk10 mitogen activated protein kinase 10 IEP RGD PMID:10950813 RGD:10412695 NCBI chr14:6,497,662...6,790,109
Ensembl chr14:6,497,707...6,786,201 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 IEP RGD PMID:10950813 RGD:10412695 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178 		JBrowse link
G Oxsr1 oxidative stress responsive kinase 1 involved_in ISO (PMID:36318922) RGD PMID:36318922 NCBI chr 8:118,972,754...119,062,102
Ensembl chr 8:118,972,754...119,062,027 		JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 IEP RGD PMID:9530152 RGD:151665787 NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191 		JBrowse link
G Rcsd1 RCSD domain containing 1 involved_in ISO (PMID:15850461) RGD PMID:15850461 NCBI chr13:77,901,898...77,964,309
Ensembl chr13:77,901,898...77,966,228 		JBrowse link
G Slc2a1 solute carrier family 2 member 1 IEP RGD PMID:11546675 RGD:12879856 NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416 		JBrowse link
G Slc6a12 solute carrier family 6 member 12 IEP RGD PMID:17022965 RGD:2316970 NCBI chr 4:154,585,386...154,603,750
Ensembl chr 4:154,585,500...154,603,750 		JBrowse link
G Stk39 serine threonine kinase 39 involved_in ISO (PMID:36318922) RGD PMID:36318922 NCBI chr 3:52,913,583...53,179,060
Ensembl chr 3:52,913,585...53,179,060 		JBrowse link
G Wnk1 WNK lysine deficient protein kinase 1 involved_in IEA
ISO
ISS
IDA		 GO_REF:0000107
(PMID:15883153), (PMID:17190791), (PMID:34289367), (PMID:36318922)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:15883153 PMID:17190791 PMID:34289367 PMID:36318922 PMID:36318922 GO_REF:0000024 GO_REF:0000107, RGD:329845496 NCBI chr 4:153,128,334...153,253,905
Ensembl chr 4:153,128,334...153,253,905 		JBrowse link
G Wnk3 WNK lysine deficient protein kinase 3 involved_in ISO (PMID:36318922) RGD PMID:36318922 NCBI chr  X:20,156,260...20,299,252
Ensembl chr  X:20,157,041...20,296,821 		JBrowse link
G Ybx3 Y box binding protein 3 involved_in ISO
IEA		 (PMID:22711822)
GO_REF:0000107		 RGD
Ensembl		 PMID:22711822 GO_REF:0000107 NCBI chr 4:165,129,747...165,153,101
Ensembl chr 4:165,129,758...165,153,161 		JBrowse link
cellular hyperosmotic salinity response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A IEP RGD PMID:17762165 RGD:2301086 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B1 involved_in ISO (PMID:8435445) RGD PMID:8435445 NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157 		JBrowse link
G Fbp1 fructose-bisphosphatase 1 IEP RGD PMID:9530152 RGD:151665787 NCBI chr17:2,207,271...2,230,076
Ensembl chr17:2,208,031...2,230,071 		JBrowse link
G Fxyd2 FXYD domain-containing ion transport regulator 2 IEP RGD PMID:15280368 RGD:1598989 NCBI chr 8:45,712,901...45,720,032
Ensembl chr 8:45,712,903...45,720,203 		JBrowse link
G Mir100 microRNA 100 acts_upstream_of_or_within ISO (PMID:17028171) RGD PMID:17028171 NCBI chr 8:41,901,225...41,901,304
Ensembl chr 8:41,901,225...41,901,304 		JBrowse link
G Mir137 microRNA 137 acts_upstream_of_or_within ISO (PMID:17028171) RGD PMID:17028171 NCBI chr 2:206,480,881...206,480,982
Ensembl chr 2:206,480,884...206,480,985 		JBrowse link
G Mir204 microRNA 204 acts_upstream_of_or_within ISO (PMID:17028171) RGD PMID:17028171 NCBI chr 1:220,316,931...220,317,040
Ensembl chr 1:220,316,931...220,317,040 		JBrowse link
G Mir29b1 microRNA 29b-1 acts_upstream_of_or_within ISO (PMID:17028171) RGD PMID:17028171 NCBI chr 4:59,650,987...59,651,067
Ensembl chr 4:59,650,986...59,651,067 		JBrowse link
G Mir29b2 microRNA 29b-2 acts_upstream_of_or_within ISO (PMID:17028171) RGD PMID:17028171 NCBI chr13:106,570,371...106,570,451
Ensembl chr13:106,570,367...106,570,456 		JBrowse link
G Mir30b microRNA 30b acts_upstream_of_or_within ISO (PMID:17028171) RGD PMID:17028171 NCBI chr 7:100,132,589...100,132,675
Ensembl chr 7:100,132,589...100,132,675 		JBrowse link
G Mir451a microRNA 451a acts_upstream_of_or_within ISO (PMID:17028171) RGD PMID:17028171 NCBI chr10:62,961,520...62,961,591
Ensembl chr10:62,961,520...62,961,591 		JBrowse link
G Mir9 microRNA 9 acts_upstream_of_or_within ISO (PMID:17028171) RGD PMID:17028171 NCBI chr 9:1,080,274...1,080,383
Ensembl chr 9:1,080,274...1,080,383 		JBrowse link
G Mir9-3 microRNA 9-3 acts_upstream_of_or_within ISO (PMID:17028171) RGD PMID:17028171 NCBI chr 1:133,440,049...133,440,138 JBrowse link
G Mir99a microRNA 99a acts_upstream_of_or_within ISO (PMID:17028171) RGD PMID:17028171 NCBI chr11:16,200,443...16,200,523
Ensembl chr11:16,200,443...16,200,523 		JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 IEP RGD PMID:9530152 RGD:151665787 NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191 		JBrowse link
G Xrcc5 X-ray repair cross complementing 5 IDA RGD PMID:11175667 RGD:2317102 NCBI chr 9:73,955,216...74,044,020
Ensembl chr 9:73,955,216...74,044,018 		JBrowse link
G Xrcc6 X-ray repair cross complementing 6 IDA RGD PMID:11175667 RGD:2317102 NCBI chr 7:113,542,992...113,563,762
Ensembl chr 7:113,543,057...113,563,762 		JBrowse link
regulation of cellular hyperosmotic salinity response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Efhd1 EF-hand domain family, member D1 involved_in ISO (PMID:26975899) RGD PMID:26975899 NCBI chr 9:87,938,259...87,984,917
Ensembl chr 9:87,938,284...87,984,917 		JBrowse link
G Letm1 leucine zipper and EF-hand containing transmembrane protein 1 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:26975899)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:26975899 GO_REF:0000024 GO_REF:0000107 NCBI chr14:76,942,647...76,982,220
Ensembl chr14:76,942,729...76,984,904 		JBrowse link
G Micu1 mitochondrial calcium uptake 1 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:26975899)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:26975899 GO_REF:0000024 GO_REF:0000107 NCBI chr20:27,668,681...27,816,322
Ensembl chr20:27,668,747...27,814,964 		JBrowse link
G Slc25a23 solute carrier family 25 member 23 involved_in ISO (PMID:26975899) RGD PMID:26975899 NCBI chr 9:1,882,636...1,898,369
Ensembl chr 9:1,882,621...1,898,561 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19694
    response to stimulus 10517
      response to stress 4181
        response to osmotic stress 116
          cellular response to osmotic stress 69
            cellular hyperosmotic response 35
              cellular hyperosmotic salinity response + 21
              intracellular accumulation of glycerol 0
Path 2
Term Annotations click to browse term
  biological_process 19694
    response to stimulus 10517
      cellular response to stimulus 8809
        cellular response to stress 1993
          cellular response to chemical stress 405
            cellular response to osmotic stress 69
              cellular hyperosmotic response 35
                cellular hyperosmotic salinity response + 21
                intracellular accumulation of glycerol 0
paths to the root