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ONTOLOGY REPORT - ANNOTATIONS


Term:response to osmotic stress
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Accession:GO:0006970 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.
Synonyms:exact_synonym: osmotic response;   osmotic stress response


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response to osmotic stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt2 AKT serine/threonine kinase 2 IEP RGD PMID:19251051 RGD:2313404 NCBI chr 1:84,400,939...84,451,223
Ensembl chr 1:84,411,726...84,450,162
JBrowse link
G Apobec1 apolipoprotein B mRNA editing enzyme catalytic subunit 1 IDA RGD PMID:10939631 RGD:1626285 NCBI chr 4:155,386,367...155,414,034
Ensembl chr 4:155,386,711...155,401,480
JBrowse link
G Atf2 activating transcription factor 2 ISO
ISS
(PMID:21098032)
GO_REF:0000024
RGD
UniProt
PMID:21098032 GO_REF:0000024 NCBI chr 3:60,721,137...60,795,951
Ensembl chr 3:60,721,135...60,795,951
JBrowse link
G Cul5 cullin 5 IEP RGD PMID:12631466 RGD:1299332 NCBI chr 8:58,199,992...58,255,149
Ensembl chr 8:58,202,821...58,253,688
JBrowse link
G Egfr epidermal growth factor receptor IEP RGD PMID:11208719 RGD:2289968 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G Fmo1 flavin containing dimethylaniline monoxygenase 1 IEP RGD PMID:19429252 RGD:2316303 NCBI chr13:80,712,885...80,745,095
Ensembl chr13:80,712,882...80,745,347
JBrowse link
G Kcnma1 potassium calcium-activated channel subfamily M alpha 1 IEA
ISO
GO_REF:0000107
(PMID:10840032), (PMID:12388065)
Ensembl
RGD
PMID:10840032, PMID:12388065 GO_REF:0000107 NCBI chr15:344,204...1,048,849
Ensembl chr15:344,360...1,047,956
JBrowse link
G LOC102550456 TSC22 domain family protein 4-like IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:21,748,608...21,761,500
Ensembl chr12:21,722,075...21,761,487
Ensembl chr12:21,722,075...21,761,487
JBrowse link
G Lrrc8a leucine rich repeat containing 8 VRAC subunit A ISS
IMP
ISO
GO_REF:0000024
PMID:28833202
(PMID:24725410), (PMID:24790029)
UniProt
RGD
PMID:24725410, PMID:24790029, PMID:28833202 GO_REF:0000024, RGD:13673739 NCBI chr 3:8,801,544...8,829,506
Ensembl chr 3:8,802,852...8,828,533
JBrowse link
G Map2k7 mitogen activated protein kinase kinase 7 IEA
IDA
ISO
GO_REF:0000107
PMID:10051439
(PMID:9535930)
Ensembl
RGD
PMID:9535930, PMID:10051439 GO_REF:0000107, RGD:2298561 NCBI chr12:2,546,278...2,555,310
Ensembl chr12:2,548,218...2,555,164
JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 IMP RGD PMID:17101801 RGD:2293490 NCBI chr 2:43,329,516...43,393,203
Ensembl chr 2:43,329,516...43,393,207
JBrowse link
G Map7 microtubule-associated protein 7 ISO PR:Q9EPK8 (MGI:MGI:2683997|PMID:14517216) RGD PMID:14517216 MGI:MGI:2683997 NCBI chr 1:15,620,665...15,748,203
Ensembl chr 1:15,620,653...15,748,203
JBrowse link
G Mapk13 mitogen activated protein kinase 13 IEA
ISO
GO_REF:0000107
(PMID:9731215)
Ensembl
RGD
PMID:9731215 GO_REF:0000107 NCBI chr20:6,018,374...6,027,467
Ensembl chr20:6,018,374...6,027,473
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 IDA RGD PMID:10781376 RGD:1582332 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Marveld3 MARVEL domain containing 3 ISO (PMID:24567356) RGD PMID:24567356 NCBI chr19:41,710,076...41,724,923
Ensembl chr19:41,710,102...41,724,923
JBrowse link
G Nfat5 nuclear factor of activated T-cells 5 IEP RGD PMID:20585028 RGD:8693586 NCBI chr19:38,446,059...38,533,735
Ensembl chr19:38,446,059...38,533,735
JBrowse link
G Nolc1 nucleolar and coiled-body phosphoprotein 1 IEP RGD PMID:10386602 RGD:2303816 NCBI chr 1:265,829,055...265,839,819
Ensembl chr 1:265,829,108...265,839,818
JBrowse link
G Pcp4 Purkinje cell protein 4 IEP RGD PMID:11003989 RGD:9850274 NCBI chr11:36,851,035...36,912,272
Ensembl chr11:36,851,038...36,912,229
JBrowse link
G Plk3 polo-like kinase 3 ISO
ISS
(PMID:21098032)
GO_REF:0000024
RGD
UniProt
PMID:21098032 GO_REF:0000024 NCBI chr 5:135,997,725...136,002,900
Ensembl chr 5:135,997,725...136,002,900
JBrowse link
G Ptk2b protein tyrosine kinase 2 beta IEP RGD PMID:11530010 RGD:1642640 NCBI chr15:42,827,306...42,947,796
Ensembl chr15:42,827,310...42,947,656
JBrowse link
G Slc2a1 solute carrier family 2 member 1 IEP RGD PMID:12006627 RGD:730230 NCBI chr 5:138,154,677...138,182,897
Ensembl chr 5:138,154,673...138,182,897
JBrowse link
G Slc6a18 solute carrier family 6 member 18 IEP RGD PMID:7943364 RGD:68841 NCBI chr 1:32,221,679...32,235,599
Ensembl chr 1:32,221,636...32,236,051
JBrowse link
G Sord sorbitol dehydrogenase IEP RGD PMID:14551351 RGD:1601363 NCBI chr 3:114,176,127...114,207,368
Ensembl chr 3:114,176,309...114,207,366
JBrowse link
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 ISO UniProtKB:Q7TQL9 (MGI:MGI:1926591|PMID:11025659), (MGI:MGI:2683997|PMID:14517216) RGD PMID:11025659, PMID:14517216 MGI:MGI:1926591, MGI:MGI:2683997 NCBI chr12:47,698,915...47,737,902
Ensembl chr12:47,698,947...47,737,902
JBrowse link
G Tsc22d2 TSC22 domain family, member 2 ISO (MGI:MGI:3699749|PMID:17147695) RGD PMID:17147695 MGI:MGI:3699749 NCBI chr 2:148,607,148...148,659,632
Ensembl chr 2:148,607,748...148,655,261
JBrowse link
G Tsc22d3 TSC22 domain family, member 3 ISO (MGI:MGI:3699749|PMID:17147695) RGD PMID:17147695 MGI:MGI:3699749 NCBI chr  X:111,884,285...111,944,693
Ensembl chr  X:111,884,295...111,887,906
JBrowse link
G Tsc22d4 TSC22 domain family, member 4 ISO
IBA
(MGI:MGI:3699749|PMID:17147695)
PMID:21873635
RGD PMID:17147695, PMID:21873635 MGI:MGI:3699749, RGD:13792537 NCBI chr12:22,008,956...22,021,814
Ensembl chr12:22,009,011...22,021,851
JBrowse link
cellular hyperosmotic response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp1 aquaporin 1 ISO
ISS
(PMID:11922632)
GO_REF:0000024
RGD
UniProt
PMID:11922632 GO_REF:0000024 NCBI chr 4:85,551,503...85,563,683
Ensembl chr 4:85,551,502...85,569,360
JBrowse link
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 ISO (PMID:22711822) RGD PMID:22711822 NCBI chr 2:187,964,100...188,022,847
Ensembl chr 2:187,977,008...188,021,377
JBrowse link
G Epo erythropoietin ISO (PMID:14569084) RGD PMID:14569084 NCBI chr12:22,274,828...22,278,268
Ensembl chr12:22,274,828...22,278,266
JBrowse link
G Errfi1 ERBB receptor feedback inhibitor 1 IEP RGD PMID:10749885 RGD:9685546 NCBI chr 5:167,951,564...167,966,011
Ensembl chr 5:167,952,728...167,966,009
JBrowse link
G Mapk10 mitogen activated protein kinase 10 IEP RGD PMID:10950813 RGD:10412695 NCBI chr14:8,079,955...8,371,508
Ensembl chr14:8,080,275...8,368,254
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 IEP RGD PMID:10950813 RGD:10412695 NCBI chr10:35,333,859...35,374,364
Ensembl chr10:35,333,859...35,374,355
JBrowse link
G Rcsd1 RCSD domain containing 1 ISO (PMID:15850461) RGD PMID:15850461 NCBI chr13:83,854,650...83,917,040
Ensembl chr13:83,854,664...83,917,021
JBrowse link
G Slc2a1 solute carrier family 2 member 1 IEP RGD PMID:11546675 RGD:12879856 NCBI chr 5:138,154,677...138,182,897
Ensembl chr 5:138,154,673...138,182,897
JBrowse link
G Slc6a12 solute carrier family 6 member 12 IEP RGD PMID:17022965 RGD:2316970 NCBI chr 4:153,921,199...153,941,333
Ensembl chr 4:153,921,115...153,941,391
JBrowse link
G Ybx3 Y box binding protein 3 ISO
IEA
(PMID:22711822)
GO_REF:0000107
RGD
Ensembl
PMID:22711822 GO_REF:0000107 NCBI chr 4:165,606,819...165,630,041
Ensembl chr 4:165,606,819...165,630,118
JBrowse link
cellular hyperosmotic salinity response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A IEP RGD PMID:17762165 RGD:2301086 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B ISO (PMID:8435445) RGD PMID:8435445 NCBI chr 4:61,706,866...61,720,959
Ensembl chr 4:61,706,864...61,720,956
JBrowse link
G Fxyd2 FXYD domain-containing ion transport regulator 2 IEP RGD PMID:15280368 RGD:1598989 NCBI chr 8:49,710,334...49,717,492
Ensembl chr 8:49,710,477...49,716,955
JBrowse link
G Mir100 microRNA 100 ISO (MGI:MGI:3691268|PMID:17028171) RGD PMID:17028171 MGI:MGI:3691268 NCBI chr 8:45,746,948...45,747,027
Ensembl chr 8:45,746,948...45,747,027
JBrowse link
G Mir137 microRNA 137 ISO (MGI:MGI:3691268|PMID:17028171) RGD PMID:17028171 MGI:MGI:3691268 NCBI chr 2:221,658,106...221,658,207
Ensembl chr 2:221,658,106...221,658,207
JBrowse link
G Mir204 microRNA 204 ISO (MGI:MGI:3691268|PMID:17028171) RGD PMID:17028171 MGI:MGI:3691268 NCBI chr 1:240,403,000...240,403,109
Ensembl chr 1:240,403,000...240,403,109
JBrowse link
G Mir29b1 microRNA 29b-1 ISO (MGI:MGI:3691268|PMID:17028171) RGD PMID:17028171 MGI:MGI:3691268 NCBI chr 4:58,344,310...58,344,390
Ensembl chr 4:58,344,310...58,344,390
JBrowse link
G Mir29b2 microRNA 29b-2 ISO (MGI:MGI:3691268|PMID:17028171) RGD PMID:17028171 MGI:MGI:3691268 NCBI chr13:113,782,057...113,782,137
Ensembl chr13:113,782,057...113,782,140
JBrowse link
G Mir30b microRNA 30b ISO (MGI:MGI:3691268|PMID:17028171) RGD PMID:17028171 MGI:MGI:3691268 NCBI chr 7:109,282,662...109,282,747
Ensembl chr 7:109,282,658...109,282,752
JBrowse link
G Mir451a microRNA 451a ISO (MGI:MGI:3691268|PMID:17028171) RGD PMID:17028171 MGI:MGI:3691268 NCBI chr10:65,291,204...65,291,275
Ensembl chr10:65,291,204...65,291,275
JBrowse link
G Mir7b microRNA 7b ISO (MGI:MGI:3691268|PMID:17028171) RGD PMID:17028171 MGI:MGI:3691268 NCBI chr 9:10,812,432...10,812,541
Ensembl chr 9:10,812,432...10,812,541
JBrowse link
G Mir9-3 microRNA 9-3 ISO (MGI:MGI:3691268|PMID:17028171) RGD PMID:17028171 MGI:MGI:3691268 NCBI chr 1:141,229,353...141,229,442 JBrowse link
G Mir99a microRNA 99a ISO (MGI:MGI:3691268|PMID:17028171) RGD PMID:17028171 MGI:MGI:3691268 NCBI chr11:16,052,153...16,052,233
Ensembl chr11:16,052,153...16,052,233
JBrowse link
G Slc12a1 solute carrier family 12 member 1 ISO (MGI:MGI:4947009|PMID:21228109) RGD PMID:21228109 MGI:MGI:4947009 NCBI chr 3:117,421,531...117,498,372
Ensembl chr 3:117,421,604...117,498,367
JBrowse link
G Xrcc5 X-ray repair cross complementing 5 IDA RGD PMID:11175667 RGD:2317102 NCBI chr 9:79,659,275...79,748,050
Ensembl chr 9:79,659,251...79,748,078
JBrowse link
G Xrcc6 X-ray repair cross complementing 6 IDA RGD PMID:11175667 RGD:2317102 NCBI chr 7:123,259,881...123,280,613
Ensembl chr 7:123,259,761...123,280,612
JBrowse link
cellular hypotonic response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp5 aquaporin 5 ISS
ISO
GO_REF:0000024
(PMID:26569106)
UniProt
RGD
PMID:26569106 GO_REF:0000024 NCBI chr 7:141,249,044...141,252,576
Ensembl chr 7:141,249,044...141,252,578
JBrowse link
G Mylk myosin light chain kinase ISO (PMID:11976941) RGD PMID:11976941 NCBI chr11:69,013,060...69,260,039
Ensembl chr11:69,013,050...69,223,158
JBrowse link
G Oxsr1 oxidative stress responsive kinase 1 ISO UniProtKB:Q9Z1W9 (MGI:MGI:5574433|PMID:24393035) RGD PMID:24393035 MGI:MGI:5574433 NCBI chr 8:127,920,349...128,009,951
Ensembl chr 8:127,920,349...128,009,951
JBrowse link
G Prkg2 protein kinase cGMP-dependent 2 ISO (MGI:MGI:5882897|PMID:15905169) RGD PMID:15905169 MGI:MGI:5882897 NCBI chr14:12,217,121...12,313,616
Ensembl chr14:12,218,553...12,315,229
JBrowse link
G Slc12a6 solute carrier family 12, member 6 ISO (PMID:24393035) RGD PMID:24393035 NCBI chr 3:103,752,213...103,852,686
Ensembl chr 3:103,753,238...103,852,686
JBrowse link
G Stk39 serine threonine kinase 39 ISO UniProtKB:Q6P9R2 (MGI:MGI:5574433|PMID:24393035) RGD PMID:24393035 MGI:MGI:5574433 NCBI chr 3:54,359,449...54,625,702
Ensembl chr 3:54,359,451...54,625,414
JBrowse link
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 ISO (MGI:MGI:2653708|PMID:12538589)
(PMID:19790068), (PMID:24474754)
(PMID:23136043)
RGD PMID:12538589, PMID:19790068, PMID:23136043, PMID:24474754 MGI:MGI:2653708 NCBI chr12:47,698,915...47,737,902
Ensembl chr12:47,698,947...47,737,902
JBrowse link
G Tspo translocator protein IEP RGD PMID:18709649 RGD:2317141 NCBI chr 7:124,460,358...124,470,610
Ensembl chr 7:124,460,358...124,470,609
JBrowse link
cellular hypotonic salinity response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc12a6 solute carrier family 12, member 6 ISO (PMID:16048901) RGD PMID:16048901 NCBI chr 3:103,752,213...103,852,686
Ensembl chr 3:103,753,238...103,852,686
JBrowse link
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 ISO (MGI:MGI:5440106|PMID:23021218) RGD PMID:23021218 MGI:MGI:5440106 NCBI chr12:47,698,915...47,737,902
Ensembl chr12:47,698,947...47,737,902
JBrowse link
cellular response to non-ionic osmotic stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO (MGI:MGI:5474549|PMID:21716255)
(PMID:21716255)
RGD PMID:21716255 MGI:MGI:5474549 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
cellular response to osmotic stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddx3x DEAD-box helicase 3, X-linked ISO (PMID:21883093) RGD PMID:21883093 NCBI chr  X:10,400,363...10,414,010
Ensembl chr  X:10,400,366...10,413,995
JBrowse link
G Dysf dysferlin ISO MGI:MGI:3055150 (MGI:MGI:5545678|PMID:24302765) RGD PMID:24302765 MGI:MGI:5545678 NCBI chr 4:115,700,942...115,901,873
Ensembl chr 4:115,712,850...115,901,873
JBrowse link
G Lrrc8c leucine rich repeat containing 8 VRAC subunit C IMP PMID:28833202 UniProt PMID:28833202 RGD:13673739 NCBI chr14:5,283,655...5,378,738
Ensembl chr14:5,283,647...5,378,726
JBrowse link
G Lrrc8d leucine rich repeat containing 8 VRAC subunit D ISS
ISO
IMP
IEA
GO_REF:0000024
(PMID:28193731)
PMID:28833202
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:28193731, PMID:28833202 GO_REF:0000024, GO_REF:0000107, RGD:13673739 NCBI chr14:5,085,606...5,194,808
Ensembl chr14:5,086,054...5,101,177
JBrowse link
G Lrrc8e leucine rich repeat containing 8 VRAC subunit E ISS
ISO
GO_REF:0000024
(PMID:28193731)
UniProt
RGD
PMID:28193731 GO_REF:0000024 NCBI chr12:2,557,267...2,568,416
Ensembl chr12:2,557,275...2,568,382
JBrowse link
G Pkd2 polycystin 2, transient receptor potential cation channel ISO (PMID:16025301) RGD PMID:16025301 NCBI chr14:6,602,004...6,645,257
Ensembl chr14:6,602,004...6,645,257
JBrowse link
G Relb RELB proto-oncogene, NF-kB subunit IDA RGD PMID:16716309 RGD:7777165 NCBI chr 1:80,517,081...80,545,019
Ensembl chr 1:80,517,411...80,544,825
JBrowse link
G Serpinb6a serpin family B member 6A ISO (PMID:20451170) RGD PMID:20451170 NCBI chr17:32,154,747...32,209,598
Ensembl chr17:32,190,801...32,209,590
JBrowse link
G Slc2a4 solute carrier family 2 member 4 ISO (MGI:MGI:3774712|PMID:18227281) RGD PMID:18227281 MGI:MGI:3774712 NCBI chr10:56,552,921...56,558,562
Ensembl chr10:56,552,983...56,558,487
JBrowse link
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 ISO
ISS
(MGI:MGI:5486547|PMID:18174177)
GO_REF:0000024
RGD
UniProt
PMID:18174177 GO_REF:0000024, MGI:MGI:5486547 NCBI chr12:47,698,915...47,737,902
Ensembl chr12:47,698,947...47,737,902
JBrowse link
G Zfand1 zinc finger AN1-type containing 1 NOT ISO (PMID:29804830) RGD PMID:29804830 NCBI chr 2:93,656,895...93,666,745
Ensembl chr 2:93,656,946...93,665,939
JBrowse link
cellular response to salt stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp1 aquaporin 1 ISO
ISS
(PMID:18509662)
GO_REF:0000024
RGD
UniProt
PMID:18509662 GO_REF:0000024 NCBI chr 4:85,551,503...85,563,683
Ensembl chr 4:85,551,502...85,569,360
JBrowse link
G Capn3 calpain 3 IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(MGI:MGI:4839427|PMID:20460380)
Ensembl
UniProt
RGD
PMID:20460380 GO_REF:0000024, GO_REF:0000107, MGI:MGI:4839427 NCBI chr 3:112,227,486...112,278,408
Ensembl chr 3:112,228,720...112,278,408
JBrowse link
G Zfp36l1 zinc finger protein 36, C3H type-like 1 ISO
ISS
(MGI:MGI:5784968|PMID:24700863)
GO_REF:0000024
RGD
UniProt
PMID:24700863 GO_REF:0000024, MGI:MGI:5784968 NCBI chr 6:103,308,032...103,313,074
Ensembl chr 6:103,308,045...103,313,074
JBrowse link
hyperosmotic response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp1 aquaporin 1 IEP
IBA
PMID:21873635 RGD
GO_Central
PMID:19776169, PMID:21873635 RGD:2316074, RGD:13792537 NCBI chr 4:85,551,503...85,563,683
Ensembl chr 4:85,551,502...85,569,360
JBrowse link
G Aqp2 aquaporin 2 IEP RGD PMID:19138132 RGD:2313121 NCBI chr 7:141,237,802...141,242,837
Ensembl chr 7:141,237,768...141,245,165
JBrowse link
G Hnmt histamine N-methyltransferase IEP RGD PMID:2429527 RGD:2316838 NCBI chr 3:905,111...937,038
Ensembl chr 3:904,765...937,102
JBrowse link
G Nts neurotensin IEP RGD PMID:8748964 RGD:9698448 NCBI chr 7:44,111,594...44,120,998
Ensembl chr 7:44,111,151...44,121,130
JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase-1 ISO (MGI:MGI:2673048|PMID:12783890) RGD PMID:12783890 MGI:MGI:2673048 NCBI chr10:13,446,373...13,525,248
Ensembl chr10:13,451,624...13,515,448
JBrowse link
G Pkn1 protein kinase N1 ISO (MGI:MGI:2673048|PMID:12783890) RGD PMID:12783890 MGI:MGI:2673048 NCBI chr19:24,803,524...24,832,305
Ensembl chr19:24,803,524...24,831,500
JBrowse link
G Rac1 Rac family small GTPase 1 ISO (MGI:MGI:2673048|PMID:12783890) RGD PMID:12783890 MGI:MGI:2673048 NCBI chr12:13,090,316...13,111,841
Ensembl chr12:13,090,172...13,111,873
JBrowse link
G Slc12a2 solute carrier family 12 member 2 IMP RGD PMID:15284343 RGD:1580437 NCBI chr18:52,917,124...52,985,281
Ensembl chr18:52,917,124...52,985,261
JBrowse link
G Slc6a18 solute carrier family 6 member 18 NAS
IEP
RGD PMID:7943364, PMID:15056985 RGD:68841, RGD:1580633 NCBI chr 1:32,221,679...32,235,599
Ensembl chr 1:32,221,636...32,236,051
JBrowse link
G Sst somatostatin IEP RGD PMID:18992283 RGD:2303157 NCBI chr11:80,358,172...80,359,449
Ensembl chr11:80,358,211...80,359,444
JBrowse link
hyperosmotic salinity response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp1 aquaporin 1 IEP RGD PMID:19596320 RGD:2316078 NCBI chr 4:85,551,503...85,563,683
Ensembl chr 4:85,551,502...85,569,360
JBrowse link
G Aqp4 aquaporin 4 IEP RGD PMID:18248364 RGD:2307072 NCBI chr18:6,766,009...6,782,757
Ensembl chr18:6,765,945...6,782,996
JBrowse link
G Avp arginine vasopressin IEP RGD PMID:18088359 RGD:2304116 NCBI chr 3:123,117,482...123,119,460
Ensembl chr 3:123,117,492...123,119,460
JBrowse link
G Avpr1b arginine vasopressin receptor 1B IEP RGD PMID:11884209 RGD:728880 NCBI chr13:48,367,307...48,378,831
Ensembl chr13:48,367,307...48,378,831
JBrowse link
G Cldn1 claudin 1 IEP RGD PMID:22733753 RGD:11341802 NCBI chr11:77,815,216...77,830,373
Ensembl chr11:77,815,181...77,830,416
JBrowse link
G Mt-cyb mitochondrially encoded cytochrome b IMP RGD PMID:8954095 RGD:634225 NCBI chr MT:14,136...15,278
Ensembl chr MT:14,136...15,278
JBrowse link
G Nkx2-1 NK2 homeobox 1 IDA RGD PMID:18395010 RGD:2303984 NCBI chr 6:77,418,096...77,423,383
Ensembl chr 6:77,418,096...77,421,286
JBrowse link
G Oxt oxytocin/neurophysin I prepropeptide IEP RGD PMID:18088359 RGD:2304116 NCBI chr 3:123,106,694...123,107,534
Ensembl chr 3:123,106,694...123,107,534
JBrowse link
G Tacr3 tachykinin receptor 3 IDA RGD PMID:18583062 RGD:2305930 NCBI chr 2:240,021,152...240,118,971
Ensembl chr 2:240,021,152...240,118,971
JBrowse link
G Trip10 thyroid hormone receptor interactor 10 IDA RGD PMID:8954095 RGD:634225 NCBI chr 9:9,689,214...9,702,353
Ensembl chr 9:9,689,475...9,702,306
JBrowse link
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 ISO MGI:MGI:2667379 (MGI:MGI:2667243|PMID:12777254) RGD PMID:12777254 MGI:MGI:2667243 NCBI chr12:47,698,915...47,737,902
Ensembl chr12:47,698,947...47,737,902
JBrowse link
hypotonic response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Itga2 integrin subunit alpha 2 IMP RGD PMID:18234883 RGD:2303705 NCBI chr 2:46,996,904...47,097,011
Ensembl chr 2:47,000,323...47,096,961
JBrowse link
G Slc12a5 solute carrier family 12 member 5 IEA
ISO
GO_REF:0000107
(PMID:12106695)
Ensembl
RGD
PMID:12106695 GO_REF:0000107 NCBI chr 3:161,433,303...161,465,078
Ensembl chr 3:161,425,988...161,462,879
JBrowse link
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 IDA RGD PMID:11081638 RGD:68824 NCBI chr12:47,698,915...47,737,902
Ensembl chr12:47,698,947...47,737,902
JBrowse link
intrinsic apoptotic signaling pathway in response to osmotic stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 ISO (MGI:MGI:5474549|PMID:21716255)
(PMID:21716255)
RGD PMID:21716255 MGI:MGI:5474549 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Scn2a sodium voltage-gated channel alpha subunit 2 ISO
ISS
IEA
MGI:MGI:2180186 (MGI:MGI:2179539|PMID:10827969)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:10827969 GO_REF:0000024, GO_REF:0000107, MGI:MGI:2179539 NCBI chr 3:51,687,910...51,822,008
Ensembl chr 3:51,687,809...51,822,250
JBrowse link
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 ISO (PMID:22711822) RGD PMID:22711822 NCBI chr 2:187,964,100...188,022,847
Ensembl chr 2:187,977,008...188,021,377
JBrowse link
G Bdkrb2 bradykinin receptor B2 ISO MGI:MGI:1857135 (MGI:MGI:3654719|PMID:16571598) RGD PMID:16571598 MGI:MGI:3654719 NCBI chr 6:129,399,468...129,429,676
Ensembl chr 6:129,399,468...129,429,676
JBrowse link
G Epo erythropoietin ISO (PMID:14569084) RGD PMID:14569084 NCBI chr12:22,274,828...22,278,268
Ensembl chr12:22,274,828...22,278,266
JBrowse link
G Ptger2 prostaglandin E receptor 2 ISO (PMID:21716255) RGD PMID:21716255 NCBI chr15:19,336,029...19,349,759
Ensembl chr15:19,338,175...19,350,210
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO (MGI:MGI:5474549|PMID:21716255)
(PMID:21716255)
RGD PMID:21716255 MGI:MGI:5474549 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Ybx3 Y box binding protein 3 ISO
IEA
(PMID:22711822)
GO_REF:0000107
RGD
Ensembl
PMID:22711822 GO_REF:0000107 NCBI chr 4:165,606,819...165,630,041
Ensembl chr 4:165,606,819...165,630,118
JBrowse link
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bdkrb2 bradykinin receptor B2 ISO
IEA
MGI:MGI:98834|MGI:MGI:99702 (MGI:MGI:3654719|PMID:16571598)
GO_REF:0000107
RGD
Ensembl
PMID:16571598 GO_REF:0000107, MGI:MGI:3654719 NCBI chr 6:129,399,468...129,429,676
Ensembl chr 6:129,399,468...129,429,676
JBrowse link
osmosensory signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Oxsr1 oxidative stress responsive kinase 1 ISO (PMID:16669787) RGD PMID:16669787 NCBI chr 8:127,920,349...128,009,951
Ensembl chr 8:127,920,349...128,009,951
JBrowse link
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 ISO
IBA
MGI:MGI:2667379 (MGI:MGI:1926591|PMID:11025659), (MGI:MGI:2653708|PMID:12538589), (MGI:MGI:2667243|PMID:12777254)
PMID:21873635
RGD PMID:11025659, PMID:12538589, PMID:12777254, PMID:21873635 MGI:MGI:1926591, MGI:MGI:2653708, MGI:MGI:2667243, RGD:13792537 NCBI chr12:47,698,915...47,737,902
Ensembl chr12:47,698,947...47,737,902
JBrowse link
G Wnk3 WNK lysine deficient protein kinase 3 ISO (PMID:27782176) RGD PMID:27782176 NCBI chr  X:20,316,081...20,459,245
Ensembl chr  X:20,316,893...20,454,357
JBrowse link
positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bad BCL2-associated agonist of cell death ISO (MGI:MGI:5474549|PMID:21716255)
(PMID:21716255)
RGD PMID:21716255 MGI:MGI:5474549 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
JBrowse link
regulation of cellular hyperosmotic salinity response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Efhd1 EF-hand domain family, member D1 ISO (PMID:26975899) RGD PMID:26975899 NCBI chr 9:94,362,249...94,408,884
Ensembl chr 9:94,362,299...94,408,885
JBrowse link
G Letm1 leucine zipper and EF-hand containing transmembrane protein 1 ISS
ISO
GO_REF:0000024
(PMID:26975899)
UniProt
RGD
PMID:26975899 GO_REF:0000024 NCBI chr14:82,227,790...82,267,298
Ensembl chr14:82,227,708...82,267,350
JBrowse link
G Micu1 mitochondrial calcium uptake 1 ISS
ISO
GO_REF:0000024
(PMID:26975899)
UniProt
RGD
PMID:26975899 GO_REF:0000024 NCBI chr20:29,284,833...29,433,617
Ensembl chr20:29,284,853...29,432,258
JBrowse link
G Slc25a23 solute carrier family 25 member 23 ISO (PMID:26975899) RGD PMID:26975899 NCBI chr 9:9,987,988...10,003,599
Ensembl chr 9:9,988,055...10,001,962
JBrowse link
regulation of cellular response to osmotic stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin ISO (PMID:23840424) RGD PMID:23840424 NCBI chr 1:197,986,384...197,999,726
Ensembl chr 1:197,986,385...197,997,664
JBrowse link
regulation of response to osmotic stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A ISO (PMID:7828597) RGD PMID:7828597 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Mlc1 modulator of VRAC current 1 ISO
IBA
(PMID:22328087)
PMID:21873635
RGD PMID:22328087, PMID:21873635 RGD:13792537 NCBI chr 7:129,949,984...129,970,314
Ensembl chr 7:129,949,967...129,970,550
JBrowse link
G Prkca protein kinase C, alpha ISO (MGI:MGI:5882922|PMID:7828597) RGD PMID:7828597 MGI:MGI:5882922 NCBI chr10:96,186,509...96,585,168
Ensembl chr10:96,191,133...96,584,947
JBrowse link
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 NOT ISO
IMP
MGI:MGI:2667379 (MGI:MGI:2667243|PMID:12777254)
PMID:23136043
RGD PMID:12777254, PMID:23136043 MGI:MGI:2667243, RGD:10400856 NCBI chr12:47,698,915...47,737,902
Ensembl chr12:47,698,947...47,737,902
JBrowse link
response to salt stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen ISO MGI:MGI:2136636 (MGI:MGI:3618038|PMID:9557921) RGD PMID:9557921 MGI:MGI:3618038 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
G Agtr1a angiotensin II receptor, type 1a IEP RGD PMID:9095078 RGD:10047102 NCBI chr17:35,907,102...35,958,136
Ensembl chr17:35,907,108...35,958,077
JBrowse link
G Agtr1b angiotensin II receptor, type 1b IEP RGD PMID:12023680 RGD:10047098 NCBI chr 2:105,149,020...105,224,335
Ensembl chr 2:105,149,020...105,224,295
JBrowse link
G Anxa7 annexin A7 ISO MGI:MGI:2159006 (MGI:MGI:3046086|PMID:12925238) RGD PMID:12925238 MGI:MGI:3046086 NCBI chr15:4,254,470...4,281,296
Ensembl chr15:4,254,499...4,281,287
JBrowse link
G Aqp2 aquaporin 2 IEP RGD PMID:12176047 RGD:625535 NCBI chr 7:141,237,802...141,242,837
Ensembl chr 7:141,237,768...141,245,165
JBrowse link
G Bax BCL2 associated X, apoptosis regulator ISO
IEA
MGI:MGI:102845|MGI:MGI:98834 (MGI:MGI:3654719|PMID:16571598)
GO_REF:0000107
RGD
Ensembl
PMID:16571598 GO_REF:0000107, MGI:MGI:3654719 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bdkrb2 bradykinin receptor B2 ISO
IEA
MGI:MGI:98834|MGI:MGI:99702 (MGI:MGI:3654719|PMID:16571598)
GO_REF:0000107
RGD
Ensembl
PMID:16571598 GO_REF:0000107, MGI:MGI:3654719 NCBI chr 6:129,399,468...129,429,676
Ensembl chr 6:129,399,468...129,429,676
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 IEP RGD PMID:20232302 RGD:4889915 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A IEP RGD PMID:19826180 RGD:11252108 NCBI chr 5:107,823,323...107,832,405
Ensembl chr 5:107,823,330...107,841,175
JBrowse link
G Cdkn2a_v1 cyclin-dependent kinase inhibitor 2A, variant 1 IEP RGD PMID:19826180 RGD:11252108
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 IEP potassium supplementation, sodium depletion RGD PMID:7678819 RGD:4391949 NCBI chr 8:62,798,317...62,809,848
Ensembl chr 8:62,779,875...62,809,893
JBrowse link
G Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 IEP RGD PMID:19118098 RGD:2307302 NCBI chr 7:116,248,759...116,255,205
Ensembl chr 7:116,156,219...116,255,167
JBrowse link
G Epo erythropoietin IEP RGD PMID:16815869 RGD:2313666 NCBI chr12:22,274,828...22,278,268
Ensembl chr12:22,274,828...22,278,266
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha IEP RGD PMID:20232302 RGD:4889915 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 IEP RGD PMID:15497505 RGD:2316936 NCBI chr 6:135,107,262...135,112,793
Ensembl chr 6:135,107,271...135,112,775
JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 IEP RGD PMID:15497505 RGD:2316936 NCBI chr 9:17,817,791...17,823,163
Ensembl chr 9:17,817,721...17,823,243
JBrowse link
G Kmo kynurenine 3-monooxygenase ISO (PMID:10672018) RGD PMID:10672018 NCBI chr13:93,684,324...93,715,378
Ensembl chr13:93,684,437...93,716,227
JBrowse link
G Mknk1 MAPK interacting serine/threonine kinase 1 ISO (MGI:MGI:87363|PMID:9155017) RGD PMID:9155017 MGI:MGI:87363 NCBI chr 5:134,691,852...134,730,887
Ensembl chr 5:134,691,881...134,730,893
JBrowse link
G Nedd4l NEDD4 like E3 ubiquitin protein ligase ISO MGI:MGI:3846431 (MGI:MGI:3846015|PMID:18524855) RGD PMID:18524855 MGI:MGI:3846015 NCBI chr18:60,392,376...60,719,720
Ensembl chr18:60,392,376...60,719,720
JBrowse link
G Pappa2 pappalysin 2 IEP RGD PMID:26534937 RGD:11553579 NCBI chr13:76,389,150...76,660,248
Ensembl chr13:76,389,150...76,660,245
JBrowse link
G Th tyrosine hydroxylase IEP RGD PMID:21113619 RGD:5128807 NCBI chr 1:216,073,034...216,080,287
Ensembl chr 1:216,073,031...216,080,287
JBrowse link
G Tp53 tumor protein p53 ISO MGI:MGI:102845|MGI:MGI:99702 (MGI:MGI:3654719|PMID:16571598) RGD PMID:16571598 MGI:MGI:3654719 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20027
    response to stimulus 10583
      response to abiotic stimulus 1511
        response to osmotic stress 123
          cellular response to osmotic stress + 58
          detection of osmotic stimulus 0
          hyperosmotic response + 49
          hypotonic response + 10
          regulation of response to osmotic stress + 16
          regulation of translation in response to osmotic stress + 0
          response to non-ionic osmotic stress + 1
          response to salt stress + 56
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.