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Gene: Oxsr1 (oxidative stress responsive kinase 1) Rattus norvegicus

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Symbol:

Oxsr1

Name:

oxidative stress responsive kinase 1

RGD ID:

1310466

Description:

Enables protein serine/threonine kinase activity. Predicted to be involved in several processes, including cellular response to osmotic stress; chemokine-mediated signaling pathway; and protein phosphorylation. Predicted to be active in cytosol. Orthologous to human OXSR1 (oxidative stress responsive kinase 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC316064; Osr1; oxidative-stress responsive 1; serine/threonine-protein kinase OSR1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	OXSR1 (oxidative stress responsive kinase 1)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Oxsr1 (oxidative-stress responsive 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Oxsr1 (oxidative stress responsive kinase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	OXSR1 (oxidative stress responsive kinase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	OXSR1 (oxidative stress responsive kinase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Oxsr1 (oxidative stress responsive kinase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	OXSR1 (oxidative stress responsive kinase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	OXSR1 (oxidative stress responsive kinase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Oxsr1 (oxidative stress responsive kinase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	OXSR1 (oxidative stress responsive kinase 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Oxsr1 (oxidative-stress responsive 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	oxsr1b (oxidative stress responsive kinase 1b)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	oxsr1a (oxidative stress responsive kinase 1a)	Alliance	DIOPT (InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	gck-3	Alliance	DIOPT (InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	fray	Alliance	DIOPT (InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	oxsr1	Alliance	DIOPT (OMA\|OrthoFinder\|PANTHER)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	127,850,481 - 127,941,518 (-)	NCBI		GRCr8
mRatBN7.2	8	118,972,754 - 119,062,102 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	118,972,754 - 119,062,027 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	8	124,554,616 - 124,644,062 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	122,753,635 - 122,843,081 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	120,586,701 - 120,676,604 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	127,920,349 - 128,009,951 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	127,920,349 - 128,009,951 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	8	127,127,110 - 127,216,712 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	8	124,196,599 - 124,286,647 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	8	124,217,575 - 124,306,410 (-)	NCBI
Celera	8	118,123,990 - 118,213,225 (-)	NCBI		Celera
Cytogenetic Map	8	q32	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Imported Disease Annotations - ClinVar

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Oxsr1	Rat	Brugada syndrome		ISO	RGD:1351310	8554872	ClinVar Annotator: match by term: Brugada syndrome	ClinVar	PMID:20129283\|PMID:22789973\|PMID:28492532
Oxsr1	Rat	Immunodeficiency 68		ISO	RGD:1351310	8554872	ClinVar Annotator: match by term: PYOGENIC BACTERIAL INFECTIONS, RECURRENT, DUE TO MYD88 DEFICIENCY	ClinVar	PMID:28492532
Oxsr1	Rat	visceral heterotaxy 4		ISO	RGD:1351310	8554872	ClinVar Annotator: match by term: Heterotaxy, visceral, 4, autosomal	ClinVar	PMID:28492532

Imported Disease Annotations - CTD

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Oxsr1	Rat	hypertension		ISO	RGD:1351310	11554173	CTD Direct Evidence: therapeutic	CTD	PMID:22949526

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Oxsr1	Rat	1,2-dichloroethane	decreases expression	ISO	RGD:1553494	6480464	ethylene dichloride results in decreased expression of OXSR1 mRNA	CTD	PMID:28960355
Oxsr1	Rat	1,2-dimethylhydrazine	multiple interactions	ISO	RGD:1553494	6480464	Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of OXSR1 mRNA]	CTD	PMID:22206623
Oxsr1	Rat	1,2-dimethylhydrazine	increases expression	ISO	RGD:1553494	6480464	1,2-Dimethylhydrazine results in increased expression of OXSR1 mRNA	CTD	PMID:22206623
Oxsr1	Rat	1-chloro-2,4-dinitrobenzene	affects binding	ISO	RGD:1351310	6480464	Dinitrochlorobenzene binds to OXSR1 protein	CTD	PMID:32991956
Oxsr1	Rat	2,3',4,4',5-Pentachlorobiphenyl	decreases expression	ISO	RGD:1553494	6480464	2,3',4,4',5-pentachlorobiphenyl results in decreased expression of OXSR1 mRNA	CTD	PMID:31388691
Oxsr1	Rat	2,3,7,8-tetrachlorodibenzodioxine	affects expression	ISO	RGD:1553494	6480464	Tetrachlorodibenzodioxin affects the expression of OXSR1 mRNA	CTD	PMID:21570461
Oxsr1	Rat	2,3,7,8-tetrachlorodibenzodioxine	decreases expression	EXP		6480464	Tetrachlorodibenzodioxin results in decreased expression of OXSR1 mRNA	CTD	PMID:33387578
Oxsr1	Rat	2,4,6-tribromophenol	increases expression	ISO	RGD:1351310	6480464	2,4,6-tribromophenol results in increased expression of OXSR1 mRNA	CTD	PMID:31675489
Oxsr1	Rat	2,4-dinitrotoluene	affects expression	EXP		6480464	2,4-dinitrotoluene affects the expression of OXSR1 mRNA	CTD	PMID:21346803
Oxsr1	Rat	2,6-dimethoxyphenol	multiple interactions	ISO	RGD:1351310	6480464	[pyrogallol 1,3-dimethyl ether co-treated with Furaldehyde] results in decreased expression of and affects the localization more ...	CTD	PMID:38598786
Oxsr1	Rat	3,3',5,5'-tetrabromobisphenol A	increases expression	ISO	RGD:1351310	6480464	tetrabromobisphenol A results in increased expression of OXSR1 protein	CTD	PMID:31675489
Oxsr1	Rat	4,4'-sulfonyldiphenol	decreases expression	ISO	RGD:1553494	6480464	bisphenol S results in decreased expression of OXSR1 mRNA	CTD	PMID:39298647
Oxsr1	Rat	6-propyl-2-thiouracil	increases expression	EXP		6480464	Propylthiouracil results in increased expression of OXSR1 mRNA	CTD	PMID:30047161
Oxsr1	Rat	actinomycin D	multiple interactions	ISO	RGD:1351310	6480464	[Dactinomycin co-treated with nutlin 3] results in increased secretion of OXSR1 protein	CTD	PMID:38460933
Oxsr1	Rat	aflatoxin B1	increases expression	ISO	RGD:1351310	6480464	Aflatoxin B1 results in increased expression of OXSR1 mRNA	CTD	PMID:27153756
Oxsr1	Rat	amitrole	increases expression	EXP		6480464	Amitrole results in increased expression of OXSR1 mRNA	CTD	PMID:30047161
Oxsr1	Rat	aristolochic acid A	decreases expression	ISO	RGD:1351310	6480464	aristolochic acid I results in decreased expression of OXSR1 mRNA	CTD	PMID:33212167
Oxsr1	Rat	arsane	multiple interactions	ISO	RGD:1351310	6480464	[Palmitic Acid co-treated with Arsenic] results in increased expression of OXSR1 mRNA	CTD	PMID:33736254
Oxsr1	Rat	arsane	increases expression	ISO	RGD:1351310	6480464	Arsenic results in increased expression of OXSR1 mRNA	CTD	PMID:33736254
Oxsr1	Rat	arsenic atom	multiple interactions	ISO	RGD:1351310	6480464	[Palmitic Acid co-treated with Arsenic] results in increased expression of OXSR1 mRNA	CTD	PMID:33736254
Oxsr1	Rat	arsenic atom	increases expression	ISO	RGD:1351310	6480464	Arsenic results in increased expression of OXSR1 mRNA	CTD	PMID:33736254
Oxsr1	Rat	arsenite(3-)	multiple interactions	ISO	RGD:1351310	6480464	arsenite inhibits the reaction [G3BP1 protein binds to OXSR1 mRNA]	CTD	PMID:32406909
Oxsr1	Rat	benzo[a]pyrene diol epoxide I	decreases expression	ISO	RGD:1351310	6480464	7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of OXSR1 mRNA	CTD	PMID:19150397
Oxsr1	Rat	benzo[e]pyrene	decreases methylation	ISO	RGD:1351310	6480464	benzo(e)pyrene results in decreased methylation of OXSR1 intron	CTD	PMID:30157460
Oxsr1	Rat	bis(2-chloroethyl) sulfide	decreases expression	ISO	RGD:1351310	6480464	Mustard Gas results in decreased expression of OXSR1 mRNA	CTD	PMID:12884408
Oxsr1	Rat	bis(2-chloroethyl) sulfide	increases expression	ISO	RGD:1351310	6480464	Mustard Gas results in increased expression of OXSR1 mRNA	CTD	PMID:25102026
Oxsr1	Rat	bisphenol A	increases expression	EXP		6480464	bisphenol A results in increased expression of OXSR1 mRNA	CTD	PMID:25181051
Oxsr1	Rat	bisphenol A	increases expression	ISO	RGD:1351310	6480464	bisphenol A results in increased expression of OXSR1 protein	CTD	PMID:37567409
Oxsr1	Rat	bisphenol A	increases methylation	EXP		6480464	bisphenol A results in increased methylation of OXSR1 gene	CTD	PMID:28505145
Oxsr1	Rat	bisphenol F	increases expression	ISO	RGD:1553494	6480464	bisphenol F results in increased expression of OXSR1 mRNA	CTD	PMID:38685157
Oxsr1	Rat	cadmium dichloride	decreases expression	EXP		6480464	Cadmium Chloride results in decreased expression of OXSR1 mRNA	CTD	PMID:33453195
Oxsr1	Rat	cadmium sulfide	increases expression	ISO	RGD:1351310	6480464	cadmium sulfide results in increased expression of OXSR1 mRNA	CTD	PMID:27866839
Oxsr1	Rat	caffeine	increases expression	EXP		6480464	Caffeine results in increased expression of OXSR1 mRNA	CTD	PMID:20864626
Oxsr1	Rat	carbon nanotube	increases expression	ISO	RGD:1553494	6480464	Nanotubes, Carbon analog results in increased expression of OXSR1 mRNA; Nanotubes, Carbon results in increased more ...	CTD	PMID:25554681
Oxsr1	Rat	chloropicrin	increases expression	ISO	RGD:1351310	6480464	chloropicrin results in increased expression of OXSR1 mRNA	CTD	PMID:26352163
Oxsr1	Rat	chlorpyrifos	increases expression	ISO	RGD:1553494	6480464	Chlorpyrifos results in increased expression of OXSR1 mRNA	CTD	PMID:37019170
Oxsr1	Rat	cisplatin	increases expression	ISO	RGD:1351310	6480464	Cisplatin results in increased expression of OXSR1 mRNA	CTD	PMID:27392435
Oxsr1	Rat	copper atom	increases expression	EXP		6480464	Copper deficiency results in increased expression of OXSR1 mRNA	CTD	PMID:26033743
Oxsr1	Rat	copper(0)	increases expression	EXP		6480464	Copper deficiency results in increased expression of OXSR1 mRNA	CTD	PMID:26033743
Oxsr1	Rat	crocidolite asbestos	decreases expression	ISO	RGD:1553494	6480464	Asbestos, Crocidolite results in decreased expression of OXSR1 mRNA	CTD	PMID:29279043
Oxsr1	Rat	dactolisib	multiple interactions	ISO	RGD:1553494	6480464	dactolisib inhibits the reaction [INS1 protein results in increased phosphorylation of OXSR1 protein]	CTD	PMID:22949526
Oxsr1	Rat	dactolisib	decreases phosphorylation	ISO	RGD:1553494	6480464	dactolisib results in decreased phosphorylation of OXSR1 protein	CTD	PMID:22949526
Oxsr1	Rat	decabromodiphenyl ether	increases expression	ISO	RGD:1351310	6480464	decabromobiphenyl ether results in increased expression of OXSR1 protein	CTD	PMID:31675489
Oxsr1	Rat	Dibutyl phosphate	affects expression	ISO	RGD:1351310	6480464	di-n-butylphosphoric acid affects the expression of OXSR1 mRNA	CTD	PMID:37042841
Oxsr1	Rat	divanadium pentaoxide	decreases expression	ISO	RGD:1351310	6480464	vanadium pentoxide results in decreased expression of OXSR1 mRNA	CTD	PMID:17459161
Oxsr1	Rat	eplerenone	multiple interactions	ISO	RGD:1553494	6480464	[eplerenone co-treated with Sodium Chloride, Dietary] results in decreased phosphorylation of OXSR1 protein	CTD	PMID:22949526
Oxsr1	Rat	epoxiconazole	decreases expression	ISO	RGD:1553494	6480464	epoxiconazole results in decreased expression of OXSR1 mRNA	CTD	PMID:35436446
Oxsr1	Rat	ethanol	increases expression	ISO	RGD:1553494	6480464	Ethanol results in increased expression of OXSR1 mRNA	CTD	PMID:30319688
Oxsr1	Rat	folic acid	decreases expression	ISO	RGD:1553494	6480464	Folic Acid results in decreased expression of OXSR1 mRNA	CTD	PMID:25629700
Oxsr1	Rat	folic acid	multiple interactions	ISO	RGD:1553494	6480464	Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of OXSR1 mRNA]	CTD	PMID:22206623
Oxsr1	Rat	FR900359	decreases phosphorylation	ISO	RGD:1351310	6480464	FR900359 results in decreased phosphorylation of OXSR1 protein	CTD	PMID:37730182
Oxsr1	Rat	furfural	multiple interactions	ISO	RGD:1351310	6480464	[pyrogallol 1,3-dimethyl ether co-treated with Furaldehyde] results in decreased expression of and affects the localization more ...	CTD	PMID:38598786
Oxsr1	Rat	gentamycin	increases expression	EXP		6480464	Gentamicins results in increased expression of OXSR1 mRNA	CTD	PMID:33387578
Oxsr1	Rat	hexadecanoic acid	multiple interactions	ISO	RGD:1351310	6480464	[Palmitic Acid co-treated with Arsenic] results in increased expression of OXSR1 mRNA	CTD	PMID:33736254
Oxsr1	Rat	ivermectin	decreases expression	ISO	RGD:1351310	6480464	Ivermectin results in decreased expression of OXSR1 protein	CTD	PMID:32959892
Oxsr1	Rat	ketamine	decreases expression	EXP		6480464	Ketamine results in decreased expression of OXSR1 mRNA	CTD	PMID:20080153
Oxsr1	Rat	methapyrilene	decreases methylation	ISO	RGD:1351310	6480464	Methapyrilene results in decreased methylation of OXSR1 intron	CTD	PMID:30157460
Oxsr1	Rat	methimazole	increases expression	EXP		6480464	Methimazole results in increased expression of OXSR1 mRNA	CTD	PMID:30047161
Oxsr1	Rat	methoxyacetic acid	increases expression	EXP		6480464	methoxyacetic acid results in increased expression of OXSR1 mRNA	CTD	PMID:20864626
Oxsr1	Rat	methylmercury chloride	increases expression	EXP		6480464	methylmercuric chloride results in increased expression of OXSR1 mRNA	CTD	PMID:20864626
Oxsr1	Rat	Monobutylphthalate	increases expression	EXP		6480464	monobutyl phthalate results in increased expression of OXSR1 mRNA	CTD	PMID:20864626
Oxsr1	Rat	N-methyl-4-phenylpyridinium	increases expression	ISO	RGD:1553494	6480464	1-Methyl-4-phenylpyridinium results in increased expression of OXSR1 protein	CTD	PMID:26558463
Oxsr1	Rat	Nutlin-3	multiple interactions	ISO	RGD:1351310	6480464	[Dactinomycin co-treated with nutlin 3] results in increased secretion of OXSR1 protein	CTD	PMID:38460933
Oxsr1	Rat	okadaic acid	increases expression	ISO	RGD:1351310	6480464	Okadaic Acid results in increased expression of OXSR1 mRNA	CTD	PMID:38832940
Oxsr1	Rat	paracetamol	decreases expression	EXP		6480464	Acetaminophen results in decreased expression of OXSR1 mRNA	CTD	PMID:33387578
Oxsr1	Rat	phenobarbital	increases expression	EXP		6480464	Phenobarbital results in increased expression of OXSR1 mRNA	CTD	PMID:30047161
Oxsr1	Rat	pirinixic acid	increases expression	ISO	RGD:1553494	6480464	pirinixic acid results in increased expression of OXSR1 mRNA	CTD	PMID:17426115\|PMID:18301758
Oxsr1	Rat	SB 431542	multiple interactions	ISO	RGD:1351310	6480464	[LDN 193189 co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with FGF2 protein] results in increased expression of OXSR1 more ...	CTD	PMID:37664457
Oxsr1	Rat	sodium arsenite	decreases expression	EXP		6480464	sodium arsenite results in decreased expression of OXSR1 protein	CTD	PMID:29459688
Oxsr1	Rat	sodium chloride	multiple interactions	ISO	RGD:1351310	6480464	[Sodium Chloride co-treated with Furaldehyde] results in decreased expression of and affects the localization of more ...	CTD	PMID:38598786
Oxsr1	Rat	sulfadimethoxine	increases expression	EXP		6480464	Sulfadimethoxine results in increased expression of OXSR1 mRNA	CTD	PMID:30047161
Oxsr1	Rat	thiram	increases expression	ISO	RGD:1351310	6480464	Thiram results in increased expression of OXSR1 mRNA	CTD	PMID:38568856
Oxsr1	Rat	trimellitic anhydride	increases expression	ISO	RGD:1553494	6480464	trimellitic anhydride results in increased expression of OXSR1 mRNA	CTD	PMID:19042947
Oxsr1	Rat	tungsten	decreases expression	ISO	RGD:1553494	6480464	Tungsten results in decreased expression of OXSR1 mRNA	CTD	PMID:30912803
Oxsr1	Rat	zearalenone	decreases expression	ISO	RGD:1553494	6480464	Zearalenone results in decreased expression of OXSR1 protein	CTD	PMID:36252740
Oxsr1	Rat	zinc atom	multiple interactions	ISO	RGD:1351310	6480464	[PCI 5002 co-treated with Zinc] results in increased expression of OXSR1 mRNA	CTD	PMID:18593933
Oxsr1	Rat	zinc(0)	multiple interactions	ISO	RGD:1351310	6480464	[PCI 5002 co-treated with Zinc] results in increased expression of OXSR1 mRNA	CTD	PMID:18593933

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Oxsr1	Rat	cell volume homeostasis	involved_in	ISO	RGD:1351310	1624291	PMID:36318922	RGD	PMID:36318922
Oxsr1	Rat	cell volume homeostasis	involved_in	IEA	UniProtKB:O95747\|ensembl:ENSP00000311713	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Oxsr1	Rat	cellular hyperosmotic response	involved_in	IBA	PANTHER:PTN000757709\|UniProtKB:O95747\|UniProtKB:Q9UEW8	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Oxsr1	Rat	cellular hyperosmotic response	involved_in	IEA	UniProtKB:O95747\|ensembl:ENSP00000311713	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Oxsr1	Rat	cellular hyperosmotic response	involved_in	ISO	RGD:1351310	1624291	PMID:36318922	RGD	PMID:36318922
Oxsr1	Rat	cellular hypotonic response	involved_in	ISO	RGD:1553494	1624291	UniProtKB:Q9Z1W9 PMID:24393035	RGD	PMID:24393035
Oxsr1	Rat	cellular hypotonic response	involved_in	IEA	UniProtKB:Q6P9R2\|ensembl:ENSMUSP00000042155	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Oxsr1	Rat	cellular response to chemokine	involved_in	ISO	RGD:1351310	1624291	PMID:27400149	RGD	PMID:27400149
Oxsr1	Rat	cellular response to chemokine	involved_in	IEA	UniProtKB:Q6P9R2\|ensembl:ENSMUSP00000042155	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Oxsr1	Rat	cellular response to chemokine	involved_in	IEA	UniProtKB:O95747\|ensembl:ENSP00000311713	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Oxsr1	Rat	cellular response to chemokine	involved_in	ISO	RGD:1553494	1624291	PMID:27400149	RGD	PMID:27400149
Oxsr1	Rat	chemokine (C-C motif) ligand 21 signaling pathway	involved_in	ISO	RGD:1553494	1624291	PMID:27400149	RGD	PMID:27400149
Oxsr1	Rat	chemokine (C-C motif) ligand 21 signaling pathway	involved_in	IEA	UniProtKB:Q6P9R2\|ensembl:ENSMUSP00000042155	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Oxsr1	Rat	chemokine (C-X-C motif) ligand 12 signaling pathway	involved_in	ISO	RGD:1351310	1624291	PMID:27400149	RGD	PMID:27400149
Oxsr1	Rat	chemokine (C-X-C motif) ligand 12 signaling pathway	involved_in	IEA	UniProtKB:O95747\|ensembl:ENSP00000311713	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Oxsr1	Rat	intracellular signal transduction	involved_in	ISO	RGD:1351310	1624291	PMID:14707132	RGD	PMID:14707132
Oxsr1	Rat	intracellular signal transduction	involved_in	IEA	UniProtKB:O95747\|ensembl:ENSP00000311713	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Oxsr1	Rat	intracellular signal transduction	involved_in	IEA	UniProtKB:Q6P9R2\|ensembl:ENSMUSP00000042155	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Oxsr1	Rat	intracellular signal transduction	involved_in	IBA	FB:FBgn0263395\|MGI:1346882\|MGI:1858416\|MGI:1917378\|PANTHER:PTN004698611\|PomBase:SPAC9G1.09\|UniProtKB:O00506\|UniProtKB:O95747\|UniProtKB:Q12851\|UniProtKB:Q8IVH8\|UniProtKB:Q92918\|UniProtKB:Q9P289\|UniProtKB:Q9UEW8\|UniProtKB:Q9Y4K4\|UniProtKB:Q9Y6E0\|dictyBase:DDB_G0286359	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Oxsr1	Rat	intracellular signal transduction	involved_in	ISO	RGD:1553494	1624291	UniProtKB:Q9Z1W9 PMID:24393035	RGD	PMID:24393035
Oxsr1	Rat	negative regulation of potassium ion transmembrane transport	involved_in	ISO	RGD:1553494	1624291	UniProtKB:Q9Z1W9 PMID:24393035	RGD	PMID:24393035
Oxsr1	Rat	negative regulation of potassium ion transmembrane transport	involved_in	IEA	UniProtKB:Q6P9R2\|ensembl:ENSMUSP00000042155	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Oxsr1	Rat	negative regulation of potassium ion transmembrane transporter activity	involved_in	ISO	RGD:1553494	1624291	UniProtKB:Q9Z1W9 PMID:24393035	RGD	PMID:24393035
Oxsr1	Rat	osmosensory signaling pathway	involved_in	ISO	RGD:1351310	1624291	PMID:16669787	RGD	PMID:16669787
Oxsr1	Rat	osmosensory signaling pathway	involved_in	IEA	UniProtKB:O95747\|ensembl:ENSP00000311713	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Oxsr1	Rat	peptidyl-threonine phosphorylation	involved_in	ISO	RGD:1553494	1624291	UniProtKB:Q9Z1W9 PMID:24393035	RGD	PMID:24393035
Oxsr1	Rat	positive regulation of T cell chemotaxis	involved_in	ISO	RGD:1351310	1624291	PMID:27400149	RGD	PMID:27400149
Oxsr1	Rat	positive regulation of T cell chemotaxis	involved_in	IEA	UniProtKB:Q6P9R2\|ensembl:ENSMUSP00000042155	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Oxsr1	Rat	positive regulation of T cell chemotaxis	involved_in	IEA	UniProtKB:O95747\|ensembl:ENSP00000311713	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Oxsr1	Rat	positive regulation of T cell chemotaxis	involved_in	ISO	RGD:1553494	1624291	PMID:27400149	RGD	PMID:27400149
Oxsr1	Rat	positive regulation of T cell chemotaxis	involved_in	IBA	MGI:1917378\|PANTHER:PTN001221360\|UniProtKB:O95747\|UniProtKB:Q9UEW8	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Oxsr1	Rat	protein autophosphorylation	involved_in	ISO	RGD:1351310	1624291	PMID:22052202	RGD	PMID:22052202
Oxsr1	Rat	protein phosphorylation	involved_in	ISO	RGD:1351310	1624291	PMID:14707132	RGD	PMID:14707132
Oxsr1	Rat	renal sodium ion absorption	involved_in	ISO	RGD:1351310	1624291	PMID:18270262	RGD	PMID:18270262
Oxsr1	Rat	renal sodium ion absorption	involved_in	IEA	UniProtKB:O95747\|ensembl:ENSP00000311713	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Oxsr1	Rat	response to oxidative stress	involved_in	ISO	RGD:1553494	1624291	PMID:12386165	RGD	PMID:12386165
Oxsr1	Rat	response to oxidative stress	involved_in	IEA	UniProtKB:Q6P9R2\|ensembl:ENSMUSP00000042155	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Oxsr1	Rat	response to xenobiotic stimulus	involved_in	ISO	RGD:1553494	1624291	MGI:1917097 PMID:24039833	RGD	PMID:24039833
Oxsr1	Rat	response to xenobiotic stimulus	involved_in	IEA	UniProtKB:Q6P9R2\|ensembl:ENSMUSP00000042155	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Oxsr1	Rat	signal transduction	involved_in	ISO	RGD:1351310	1624291	PMID:16669787	RGD	PMID:16669787
Oxsr1	Rat	signal transduction	involved_in	IEA	UniProtKB:O95747\|ensembl:ENSP00000311713	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Oxsr1	Rat	cytoplasm	is_active_in	ISO	RGD:1351310	1624291	PMID:22989884	RGD	PMID:22989884
Oxsr1	Rat	cytoplasm	located_in	IEA	UniProtKB-KW:KW-0963	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Oxsr1	Rat	cytoplasm	is_active_in	IEA	UniProtKB:O95747\|ensembl:ENSP00000311713	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Oxsr1	Rat	cytoplasm	is_active_in	IBA	FB:FBgn0023083\|FB:FBgn0035001\|FB:FBgn0263395\|PANTHER:PTN004698611\|PomBase:SPBC17F3.02\|RGD:1561742\|RGD:1563568\|RGD:621643\|RGD:727809\|UniProtKB:O00506\|UniProtKB:O95747\|UniProtKB:Q57ZC6\|UniProtKB:Q9H2G2\|UniProtKB:Q9P289\|UniProtKB:Q9UEW8\|UniProtKB:Q9Y4K4\|UniProtKB:Q9Y6E0\|WB:WBGene00001526\|WB:WBGene00013355\|dictyBase:DDB_G0283265\|dictyBase:DDB_G0286359	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Oxsr1	Rat	cytoplasm	located_in	IEA	UniProtKB-SubCell:SL-0086	1600115	GO_REF:0000044	UniProt	GO_REF:0000044
Oxsr1	Rat	cytosol	is_active_in	IBA	PANTHER:PTN001221360\|RGD:621643\|UniProtKB:O95747\|UniProtKB:Q9UEW8	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Oxsr1	Rat	cytosol	located_in	IEA	UniProtKB:O95747\|ensembl:ENSP00000311713	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Oxsr1	Rat	cytosol	located_in	ISO	RGD:1351310	1624291		RGD	GO_REF:0000052

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Oxsr1	Rat	ATP binding	enables	ISO	RGD:1351310	1624291	PMID:14707132	RGD	PMID:14707132
Oxsr1	Rat	ATP binding	enables	IEA	UniProtKB:O95747\|ensembl:ENSP00000311713	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Oxsr1	Rat	ATP binding	enables	IEA	InterPro:IPR000719\|InterPro:IPR024678	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Oxsr1	Rat	ATP binding	enables	IEA	UniRule:UR001503341	1600115	GO_REF:0000104	UniProt	GO_REF:0000104
Oxsr1	Rat	ATP binding	enables	IEA	UniProtKB-KW:KW-0067	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Oxsr1	Rat	ATP binding	enables	IEA	InterPro:IPR000719\|InterPro:IPR017441\|InterPro:IPR024678	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Oxsr1	Rat	identical protein binding	enables	ISO	RGD:1351310	1624291	UniProtKB:O95747 PMID:16832045	RGD	PMID:16832045
Oxsr1	Rat	identical protein binding	enables	IEA	UniProtKB:O95747\|ensembl:ENSP00000311713	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Oxsr1	Rat	ion channel regulator activity	enables	IEA	UniProtKB:O95747\|ensembl:ENSP00000311713	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Oxsr1	Rat	ion channel regulator activity	enables	ISO	RGD:1351310	1624291	PMID:16669787	RGD	PMID:16669787
Oxsr1	Rat	kinase activity	enables	IEA	UniProtKB-KW:KW-0418	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Oxsr1	Rat	magnesium ion binding	enables	ISO	RGD:1351310	1624291	PMID:14707132	RGD	PMID:14707132
Oxsr1	Rat	magnesium ion binding	enables	IEA	UniProtKB:O95747\|ensembl:ENSP00000311713	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Oxsr1	Rat	metal ion binding	enables	IEA	UniProtKB-KW:KW-0479	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Oxsr1	Rat	nucleotide binding	enables	IEA	UniProtKB-KW:KW-0547	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Oxsr1	Rat	nucleotide binding	enables	IEA	UniRule:UR001503341	1600115	GO_REF:0000104	UniProt	GO_REF:0000104
Oxsr1	Rat	potassium channel inhibitor activity	enables	IEA	UniProtKB:O95747\|ensembl:ENSP00000311713	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Oxsr1	Rat	potassium channel inhibitor activity	enables	ISO	RGD:1351310	1624291	PMID:24393035	RGD	PMID:24393035
Oxsr1	Rat	potassium channel inhibitor activity	enables	IEA	UniProtKB:Q6P9R2\|ensembl:ENSMUSP00000042155	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Oxsr1	Rat	protein binding	enables	ISO	RGD:1351310	1624291	UniProtKB:P55011\|UniProtKB:Q8NC24\|UniProtKB:Q96J92\|UniProtKB:Q9H4A3\|UniProtKB:Q9Y376\|UniProtKB:Q9Y3S1 PMID:16669787, PMID:16832045, PMID:17721439, PMID:21423148, PMID:24393035, PMID:25416956, PMID:28514442, PMID:32296183, PMID:33961781, PMID:35044719, PMID:35271311	RGD	PMID:16669787\|PMID:16832045\|PMID:17721439\|PMID:21423148\|PMID:24393035\|PMID:25416956\|PMID:28514442\|PMID:32296183\|PMID:33961781\|PMID:35044719\|PMID:35271311
Oxsr1	Rat	protein binding	enables	ISO	RGD:1553494	1624291	PR:P55012\|PR:P55014\|PR:Q924N4\|UniProtKB:Q924N4 PMID:12386165, PMID:27782176	RGD	PMID:12386165\|PMID:27782176
Oxsr1	Rat	protein kinase activity	enables	IEA	InterPro:IPR000719	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Oxsr1	Rat	protein kinase binding	enables	ISO	RGD:1351310	1624291	UniProtKB:Q9H4A3 PMID:16669787	RGD	PMID:16669787
Oxsr1	Rat	protein kinase binding	enables	IEA	UniProtKB:O95747\|ensembl:ENSP00000311713	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Oxsr1	Rat	protein serine/threonine kinase activity	enables	IDA		329845507	PMID:22544747	UniProt
Oxsr1	Rat	protein serine/threonine kinase activity	enables	IEA	UniProtKB-KW:KW-0723	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Oxsr1	Rat	protein serine/threonine kinase activity	enables	IEA	UniProtKB:O95747\|ensembl:ENSP00000311713	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Oxsr1	Rat	protein serine/threonine kinase activity	enables	IEA	UniProtKB:Q6P9R2\|ensembl:ENSMUSP00000042155	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Oxsr1	Rat	protein serine/threonine kinase activity	enables	IBA	FB:FBgn0023083\|FB:FBgn0035001\|FB:FBgn0263395\|MGI:1346882\|MGI:1858416\|MGI:1917378\|PANTHER:PTN004698611\|PomBase:SPAC9G1.09\|RGD:1310466\|RGD:621643\|UniProtKB:O94804\|UniProtKB:O95747\|UniProtKB:Q12851\|UniProtKB:Q8IVH8\|UniProtKB:Q92918\|UniProtKB:Q9H2G2\|UniProtKB:Q9UEW8\|UniProtKB:Q9Y4K4\|UniProtKB:Q9Y6E0\|WB:WBGene00001526\|WB:WBGene00013355\|dictyBase:DDB_G0286359	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Oxsr1	Rat	protein serine/threonine kinase activity	enables	IEA	EC:2.7.11.1	1600115	GO_REF:0000003	UniProt	GO_REF:0000003
Oxsr1	Rat	protein serine/threonine kinase activity	enables	ISO	RGD:1553494	1624291	UniProtKB:Q9Z1W9 PMID:24393035	RGD	PMID:24393035
Oxsr1	Rat	protein serine/threonine kinase activity	enables	IEA	InterPro:IPR024678	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Oxsr1	Rat	protein serine/threonine kinase activity	enables	IEA	ARBA:ARBA00027016	1600115	GO_REF:0000117	UniProt	GO_REF:0000117
Oxsr1	Rat	protein serine/threonine kinase activity	enables	ISO	RGD:1351310	1624291	PMID:14707132, PMID:16669787, PMID:18270262, PMID:19665974, PMID:21321328, PMID:24393035	RGD	PMID:14707132\|PMID:16669787\|PMID:18270262\|PMID:19665974\|PMID:21321328\|PMID:24393035
Oxsr1	Rat	transferase activity	enables	IEA	UniProtKB-KW:KW-0808	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Oxsr1	Rat	transmembrane transporter binding	enables	IEA	UniProtKB:Q6P9R2\|ensembl:ENSMUSP00000042155	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Oxsr1	Rat	transmembrane transporter binding	enables	ISO	RGD:1351310	1624291	UniProtKB:Q9UP95 PMID:24393035	RGD	PMID:24393035
Oxsr1	Rat	transmembrane transporter binding	enables	IEA	UniProtKB:O95747\|ensembl:ENSP00000311713	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107

Disease Annotations Click to see Annotation Detail View

Brugada syndrome (ISO)

hypertension (ISO)

Immunodeficiency 68 (ISO)

visceral heterotaxy 4 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

1-chloro-2,4-dinitrobenzene (ISO)

2,3',4,4',5-Pentachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4,6-tribromophenol (ISO)

2,4-dinitrotoluene (EXP)

2,6-dimethoxyphenol (ISO)

3,3',5,5'-tetrabromobisphenol A (ISO)

4,4'-sulfonyldiphenol (ISO)

6-propyl-2-thiouracil (EXP)

actinomycin D (ISO)

aflatoxin B1 (ISO)

amitrole (EXP)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenite(3-) (ISO)

benzo[a]pyrene diol epoxide I (ISO)

benzo[e]pyrene (ISO)

bis(2-chloroethyl) sulfide (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

cadmium dichloride (EXP)

cadmium sulfide (ISO)

caffeine (EXP)

carbon nanotube (ISO)

chloropicrin (ISO)

chlorpyrifos (ISO)

cisplatin (ISO)

copper atom (EXP)

copper(0) (EXP)

crocidolite asbestos (ISO)

dactolisib (ISO)

decabromodiphenyl ether (ISO)

Dibutyl phosphate (ISO)

divanadium pentaoxide (ISO)

eplerenone (ISO)

epoxiconazole (ISO)

ethanol (ISO)

folic acid (ISO)

FR900359 (ISO)

furfural (ISO)

gentamycin (EXP)

hexadecanoic acid (ISO)

ivermectin (ISO)

ketamine (EXP)

methapyrilene (ISO)

methimazole (EXP)

methoxyacetic acid (EXP)

methylmercury chloride (EXP)

Monobutylphthalate (EXP)

N-methyl-4-phenylpyridinium (ISO)

Nutlin-3 (ISO)

okadaic acid (ISO)

paracetamol (EXP)

phenobarbital (EXP)

pirinixic acid (ISO)

SB 431542 (ISO)

sodium arsenite (EXP)

sodium chloride (ISO)

sulfadimethoxine (EXP)

thiram (ISO)

trimellitic anhydride (ISO)

tungsten (ISO)

zearalenone (ISO)

zinc atom (ISO)

zinc(0) (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cell volume homeostasis (IEA,ISO)

cellular hyperosmotic response (IBA,IEA,ISO)

cellular hypotonic response (IEA,ISO)

cellular response to chemokine (IEA,ISO)

chemokine (C-C motif) ligand 21 signaling pathway (IEA,ISO)

chemokine (C-X-C motif) ligand 12 signaling pathway (IEA,ISO)

intracellular signal transduction (IBA,IEA,ISO)

negative regulation of potassium ion transmembrane transport (IEA,ISO)

negative regulation of potassium ion transmembrane transporter activity (ISO)

osmosensory signaling pathway (IEA,ISO)

peptidyl-threonine phosphorylation (ISO)

positive regulation of T cell chemotaxis (IBA,IEA,ISO)

protein autophosphorylation (ISO)

protein phosphorylation (ISO)

renal sodium ion absorption (IEA,ISO)

response to oxidative stress (IEA,ISO)

response to xenobiotic stimulus (IEA,ISO)

signal transduction (IEA,ISO)

Cellular Component

cytoplasm (IBA,IEA,ISO)

cytosol (IBA,IEA,ISO)

Molecular Function

ATP binding (IEA,ISO)

identical protein binding (IEA,ISO)

ion channel regulator activity (IEA,ISO)

kinase activity (IEA)

magnesium ion binding (IEA,ISO)

metal ion binding (IEA)

nucleotide binding (IEA)

potassium channel inhibitor activity (IEA,ISO)

protein binding (ISO)

protein kinase activity (IEA)

protein kinase binding (IEA,ISO)

protein serine/threonine kinase activity (IBA,IDA,IEA,ISO)

transferase activity (IEA)

transmembrane transporter binding (IEA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	Taurine inhibits K+-Cl- cotransporter KCC2 to regulate embryonic Cl- homeostasis via with-no-lysine (WNK) protein kinase signaling pathway.	Inoue K, etal., J Biol Chem. 2012 Jun 15;287(25):20839-50. doi: 10.1074/jbc.M111.319418. Epub 2012 Apr 27.
4.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
6.	The WNK1 and WNK4 protein kinases that are mutated in Gordon's hypertension syndrome phosphorylate and activate SPAK and OSR1 protein kinases.	Vitari AC, etal., Biochem J. 2005 Oct 1;391(Pt 1):17-24.

Additional References at PubMed

PMID:12386165	PMID:14707132	PMID:16669787	PMID:16832045	PMID:19056867	PMID:22052202	PMID:24393035	PMID:25515571	PMID:27400149	PMID:31362998	PMID:31954517

Genomics

Comparative Map Data

Oxsr1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	127,850,481 - 127,941,518 (-)	NCBI		GRCr8
mRatBN7.2	8	118,972,754 - 119,062,102 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	118,972,754 - 119,062,027 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	8	124,554,616 - 124,644,062 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	122,753,635 - 122,843,081 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	120,586,701 - 120,676,604 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	127,920,349 - 128,009,951 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	127,920,349 - 128,009,951 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	8	127,127,110 - 127,216,712 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	8	124,196,599 - 124,286,647 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	8	124,217,575 - 124,306,410 (-)	NCBI
Celera	8	118,123,990 - 118,213,225 (-)	NCBI		Celera
Cytogenetic Map	8	q32	NCBI

OXSR1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	38,164,063 - 38,255,484 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	38,165,089 - 38,255,484 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	3	38,207,028 - 38,296,975 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	38,182,030 - 38,271,983 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	3	38,182,029 - 38,271,979	NCBI
Celera	3	38,142,644 - 38,232,606 (+)	NCBI		Celera
Cytogenetic Map	3	p22.2	NCBI
HuRef	3	38,248,039 - 38,338,925 (+)	NCBI		HuRef
CHM1_1	3	38,158,703 - 38,248,663 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	3	38,170,735 - 38,261,199 (+)	NCBI		T2T-CHM13v2.0

Oxsr1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	119,067,498 - 119,154,475 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	9	119,067,498 - 119,151,493 (-)	Ensembl		GRCm39 Ensembl
GRCm38	9	119,238,432 - 119,322,684 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	119,238,432 - 119,322,427 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	9	119,149,784 - 119,213,966 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	9	119,087,131 - 119,171,125 (-)	NCBI		MGSCv36	mm8
Celera	9	119,708,063 - 119,774,018 (-)	NCBI		Celera
Cytogenetic Map	9	F3	NCBI
cM Map	9	71.33	NCBI

Oxsr1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955427	25,575,655 - 25,696,356 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955427	25,575,655 - 25,696,356 (+)	NCBI	ChiLan1.0	ChiLan1.0

OXSR1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	2	38,115,759 - 38,209,133 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	3	38,120,761 - 38,213,897 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	38,063,299 - 38,153,609 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	38,345,491 - 38,436,279 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	38,345,504 - 38,436,275 (+)	Ensembl	panpan1.1		panPan2

OXSR1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	23	7,931,636 - 8,026,591 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	23	7,932,254 - 8,024,323 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	23	7,973,576 - 8,067,716 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	23	8,221,226 - 8,313,574 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	23	8,221,839 - 8,315,902 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	23	8,035,117 - 8,130,106 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	23	8,175,999 - 8,270,428 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	23	8,168,533 - 8,263,795 (+)	NCBI		UU_Cfam_GSD_1.0

Oxsr1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	194,421,183 - 194,519,453 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936473	27,559,752 - 27,658,329 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936473	27,559,756 - 27,658,299 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

OXSR1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	23,020,530 - 23,116,958 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	13	23,020,839 - 23,116,957 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	25,225,156 - 25,288,185 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

OXSR1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	15	1,164,529 - 1,255,935 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	15	1,164,528 - 1,255,925 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666063	9,895,779 - 9,985,796 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Oxsr1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624731	2,703,301 - 2,826,419 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624731	2,703,295 - 2,825,017 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Oxsr1
339 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	363
Count of miRNA genes:	217
Interacting mature miRNAs:	265
Transcripts:	ENSRNOT00000018056
Prediction methods:	Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2303171	Bp331	Blood pressure QTL 331	5.57	0.005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	61290298	119084929	Rat
738011	Anxrr9	Anxiety related response QTL 9	6.1		exploratory behavior trait (VT:0010471)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	8	93535351	123900184	Rat
724539	Cm19	Cardiac mass QTL 19	2.6		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	8	100149864	120994388	Rat
1358903	Bp252	Blood pressure QTL 252	7	0.0001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	93965141	123900184	Rat
70197	BpQTLcluster8	Blood pressure QTL cluster 8	3.482		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	46531639	119088626	Rat
738014	Anxrr15	Anxiety related response QTL 15	3.6	0.005	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	8	95718998	123900184	Rat
2300182	Bmd56	Bone mineral density QTL 56	5.4		femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	8	95718998	123900184	Rat
1554321	Bmd3	Bone mineral density QTL 3	7.9	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	8	40952565	123900184	Rat
2300181	Bmd55	Bone mineral density QTL 55	5.7	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	8	76468691	121468691	Rat
1358893	Bp263	Blood pressure QTL 263	5.01		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	93965141	123900184	Rat
61437	Cia6	Collagen induced arthritis QTL 6			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	8	82460758	122812818	Rat

Markers in Region

D8Got351

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	119,056,955 - 119,057,094 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	128,004,880 - 128,005,018	NCBI	Rnor6.0
Rnor_5.0	8	127,211,641 - 127,211,779	UniSTS	Rnor5.0
RGSC_v3.4	8	124,281,577 - 124,281,715	UniSTS	RGSC3.4
Celera	8	118,208,155 - 118,208,293	UniSTS
Cytogenetic Map	8	q32	UniSTS

RH130404

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	118,972,931 - 118,973,114 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	127,920,527 - 127,920,709	NCBI	Rnor6.0
Rnor_5.0	8	127,127,288 - 127,127,470	UniSTS	Rnor5.0
RGSC_v3.4	8	124,196,777 - 124,196,959	UniSTS	RGSC3.4
Celera	8	118,124,168 - 118,124,350	UniSTS
RH 3.4 Map	8	1302.4	UniSTS
Cytogenetic Map	8	q32	UniSTS

RH132547

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	119,062,968 - 119,063,160 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	128,010,892 - 128,011,083	NCBI	Rnor6.0
Rnor_5.0	8	127,217,653 - 127,217,844	UniSTS	Rnor5.0
RGSC_v3.4	8	124,287,588 - 124,287,779	UniSTS	RGSC3.4
Celera	8	118,214,166 - 118,214,357	UniSTS
RH 3.4 Map	8	1288.5	UniSTS
Cytogenetic Map	8	q32	UniSTS

RH143190

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	119,037,457 - 119,037,569 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	127,985,006 - 127,985,117	NCBI	Rnor6.0
Rnor_5.0	8	127,191,767 - 127,191,878	UniSTS	Rnor5.0
RGSC_v3.4	8	124,262,083 - 124,262,194	UniSTS	RGSC3.4
Celera	8	118,188,661 - 118,188,772	UniSTS
RH 3.4 Map	8	1312.6	UniSTS
Cytogenetic Map	8	q32	UniSTS

RH139291

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	119,037,318 - 119,037,445 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	127,984,867 - 127,984,993	NCBI	Rnor6.0
Rnor_5.0	8	127,191,628 - 127,191,754	UniSTS	Rnor5.0
RGSC_v3.4	8	124,261,944 - 124,262,070	UniSTS	RGSC3.4
Celera	8	118,188,522 - 118,188,648	UniSTS
Cytogenetic Map	8	q32	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001108194	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063265654	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063265655	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473954	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000008	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000018056 ⟹ ENSRNOP00000018056

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	8	118,972,754 - 119,062,027 (-)	Ensembl
Rnor_6.0 Ensembl	8	127,920,349 - 128,009,951 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000099478 ⟹ ENSRNOP00000079676

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	8	118,972,754 - 119,062,027 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000108136 ⟹ ENSRNOP00000085510

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	8	118,972,764 - 119,044,576 (-)	Ensembl

RefSeq Acc Id:

NM_001108194 ⟹ NP_001101664

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	127,850,484 - 127,939,750 (-)	NCBI
mRatBN7.2	8	118,972,754 - 119,062,027 (-)	NCBI
Rnor_6.0	8	127,920,349 - 128,009,951 (-)	NCBI
Rnor_5.0	8	127,127,110 - 127,216,712 (-)	NCBI
RGSC_v3.4	8	124,196,599 - 124,286,647 (-)	RGD
Celera	8	118,123,990 - 118,213,225 (-)	RGD

Sequence:

show sequence

AGGGCGGGACGGAGGGGCAGGGCCGGGAAGAAGCTCTCTTCGCGGTGCCGCGGAGGCTGAGGCC
GGCTCGTGGGCTGGGCCGGGGACTGCGGGACACGGAGCCGCAGGAGGCGAGTTCGGCCGCAGCC
GCGCGTCCCCGCCTCGGGCCCGCGCTTGACCCGCGCGCCCCGGCGTTGTGCGCCCCAAGGCTGG
GCCAAGCGGCGGGTTGGGGGCGGCTGGGCGTGGGGAGGCGCGCGGCGAGGTGACCCGAGAGCCC
CAAGCGTGAGAAGCACGGAGCCAGGCGCTGCAGCCGTCATGTCCGAGGACTCGAGCGCCCTGCC
CTGGTCCATCAACAGGGACGACTACGAGCTGCAGGAGGTGATCGGGAGTGGAGCAACTGCTGTG
GTCCAAGCAGCTTACTGTGCCCCCAAAAAGGAGAGAGTGGCAATCAAACGGATAAACCTGGAGA
AGTGTCAGACGAGCATGGATGAGCTCCTGAAAGAAATCCAAGCTATGAGTCAATGCCATCATCC
TAACATTGTGTCTTACTACACATCCTTTGTGGTAAAAGATGAGCTGTGGCTGGTCATGAAGCTG
CTAAGTGGAGGTTCCGTTCTGGATATTATTAAACACATTGTGGCAAAGGGGGAACATAAGGGCG
GAGTTTTGGATGAGTCGACCATCGCTACAATCCTCCGAGAAGTCTTAGAAGGACTGGAGTACCT
GCACAAGAACGGGCAGATCCACAGAGATGTGAAAGCTGGGAACATTCTTCTAGGAGAAGACGGC
TCTGTGCAGATTGCAGATTTCGGTGTTAGTGCTTTTTTAGCCACTGGTGGTGACATTACCAGAA
ATAAAGTAAGAAAGACGTTTGTTGGCACCCCGTGCTGGATGGCACCTGAAGTTATGGAGCAGGT
TCGAGGTTATGATTTTAAAGCTGATATCTGGAGTTTTGGAATCACAGCGATTGAACTAGCCACA
GGGGCAGCTCCTTATCATAAATATCCTCCAATGAAGGTTTTAATGCTGACACTCCAGAACGATC
CTCCTTCTTTGGATACTGGTGTTCAAGATAAAGAAATGCTGAAAAAATATGGAAAATCATTTAG
AAAAATGATTTCATTGTGCCTTCAAAAGGATCCAGAAAAAAGACCAACAGCAGCAGAACTGTTG
AGGCACAAGTTTTTCCAGAAGGCAAAGAATAAAGAATTTCTTCAAGAAAAAATACTACAGAGAG
CACCTACCATCTCTGAAAGATCTAAAAAGGTCCGGAGAGTGCCCGGCTCCAGCGGCCGTCTCCA
TAAGACAGAGGATGGAGGCTGGGAGTGGAGCGACGATGAGTTTGATGAGGAGAGCGAGGAAGGG
AAAGCTGCGATTTCTCAGCTCAGGTCTCCCCGAGTAAAAGACTCATTGTCAAATTCTGAGCTCT
TCTCGGCCGCTGATCCCATGGGGACTTTGCTTCAAGTTCCAGAACAAATTTCTGCACATCTACC
TCAGCCAGCTAGCCAGATGCCCACACAGCCAGCTCAAGTCTCTCTCCTGCCCCCTGCAGAGCCA
GCAAAGCCAGCACAGGCTCGATCTTCAGGAGAGCGGTCCCAGGAGACCAAGGTCCCTATCAGTC
TAGTGCTAAGATTAAGGAATTCCAAAAAAGAACTAAATGATATTCGATTTGAATTTACTCCTGG
GAGAGATACAGCAGAGGGTGTTTCTCAGGAGCTCATTTCTGCTGGCCTGGTCGACGGAAGGGAT
TTAGTGATAGTGGCAGCTAATTTGCAGAAAATTGTGGAAGAACCTCAGTCAAATCGATCTGTCA
CTTTCAAACTGGCATCTGGTGTTGAAGGCTCGGATATTCCTGATGATGGCAAACTGATAGGATT
TGCCCAGCTCAGCATCAGCTAAACCACAGCCCCGGAAGAGTCAGCCTAGGAGACGCCACACATG
CACATGTCTGTTGCTTCTGTTGGCCTGAACCTACAACTGCCAAAGAACCCAGCAAGGAACCTCC
CAGCTCGGAGCTTTAGTTTTTCTCTTTGTTTTTCTTGCCTCCGCCCTTCTGCCCCCCTTTTCCT
ACAAGGAAAGAAAAGTTGGATCACCTGTGGCCAGCATCCCCTCAGAGAGTTCCGTTGGTAGACA
CGTTGCTCATGTGCCCTCTCCCTCCACGTGAGAGGCAGAAGTGGCCAGTGTGCCTCGAGGCCCA
GGATGGAAGTCTCTCAGCTCATTCTTGCCTTACTAAGTTGTTGGCCCCAGTGGATCGAGCAGCC
GCACTGGGCAGCCTCATCTTGCCTGCTCTCCCACACCTGCTGGGACATGAGCATCTTGGGATAA
CTCTCTAACACTCAAGTAGCAATTAAAAGTTGATTGTTCAGCTGGAGCCCAGAGAATTTAATTA
CTTTTTTTTTTCTTTGTACCTGGTGTGAATTCTAGCAACCTTTGTTAGAAAAAAAGCACAGCCT
CGAATGGAGGCAGCCTAAACTCTTGTCTGTCTCCTTCATGGTGTCTCTTACATGTTTTGCTGAG
CTGTTCTCAGGCTGTTCTCAGGCACCCCCTTCACTGCTCCCTCCAGAAAGGGTTGCTAGCCTTA
ACTTCAGCTGGTGCGAAACATCTGACTGTCGTCAGACTTCAGCCATCTCCTTCAGAGTGCACCT
TTGGATCGTTTACGCAGAAAACATCAAGCAATGGCTTATAAATCTTATCTTGCCAGAGGTAGTT
TTTGAACAAGAAGAGAACTTTGTAAATCTTATCATTGGGAAAGTATTTTCGATATTTAAAAAAA
TTAAACTGAAGAAAAACTGATCTTTGACCCTCCTATGAAGATGGATTTGCCTGGCCTCTAAGTC
ATGAGGAAATGGTGTACACCGCTGAGAGTTTTACAGCAATAAAGGAGACTCACACGAGGCTAGA
GGCCTGCCTCTGCTCCTCTCTCGCACTGACTCTGCAGGGCTTCTTCATTCGCTCAACTGCCCAA
GACGGAACCTGAAGCCACCCGTGCTGTAACCTTAGGCTCATGAGTAGACGGTGTTCATTTGATG
TTCTAGAAATTATGTGACTTATTCTTTAGGGTAAAAAGTGAGCTCAATGCAATATGGTTATAAT
CAGTGAAGTTGGCTTTTCTTTTTTCCTATCGTTAAATAGCATTTGTCTAATTGCTAATAAGCCT
ACCAAGTTACCAGATTGTATATGAGAGTGGAATAGTCAAGTCTGGCCTTAAAGAGACAAAGATG
GGCTGTGAGCCCCTAGAGTGGGACTAGTTCGTTGCCTTTTATAGAATTCCTTGCACCCGCCATT
GTTGGTTTGATGAACAAGATTAGTACCCAGTTTGTTTCCACCCTCACCCCACCTCACCCAGTTG
AGGATCACAGTGCTGCTCCTATGAGCAGCTCCGTTGACTTTTTTCTTGGAACACACCTGAGAGC
TTTCCCCATCTCTGACTTGTGCCACCTCATGTTTCATTCATACTGAGCCTATAGTTTCAGTCAT
GGACTTTCATACTGCAGAGTGCAAAGGCATGTTGGGAAAGGTGTTGGAGAGGAAGAGAAGATGG
ATTTGAGAAGGGAATTGAGAGAATAGAGAGTCCAAGGTCCCAGCAGGTTGGTAAAAGGAGGAAC
CTGTTGAGCTAGGAGGGAGAAAAAAGATTGAGCAGCTAGTTGGAAACCATTTTTTTTCTTTCTT
CTTTCCCCACTTGTTAGAGGTAGGGTTGTGAGGAAGCAAAGAAGGGGAGGTGGGATGGAGTCTA
GGAAGCAGGCAGTGTTGCCTTTGGCAGAAGGCTCATGGCCTGCTGTAGAATTCAATCTGGTTTC
AGCAGCTTGACTTAATTCACTTAAGGGCTCAGGAAGGAATGGATATCACTGTTCTGGCTTTCGA
CTTAGGGGGTGCTCCAGTGCCAGGTTGGAAGTAAGCAGCAGCCTATCTCTTGTTCTCTAGACCA
TCATCACCTTTGCCTTGCTGTGAGGGGACAGACATGACAGTAAAAGTGGCCTGGGGCTCTTTTT
CTGTTCATGGTTTGCTTTTTTGGCAAGGAGGAGGTCGGCACTAAGACCCAGGACAATGTTACTT
CTCCGTGATGTGTGGTGACTTCCTTCTGCTGGCTTATGCAGTGATGGCGAGAGAACCAGTCAGC
GGCGGAAACTGCAGAGATGGGACAGCTCAGAAGCCAGGGAGCTAGAGCAGAGCTTCCAGGGGAC
TCTGCCATTAAGTCCTCAAGATGCCCGTGTCCCTGGAGTAGGGACTGACTATAGCACAAGATAG
TGTGTGCCAATATAGCCAAGAGAATGTGTGAAATAGTCTTTCTAAATGATAAAGGCATCATTTG
GGTTGGTTCTTGTTTTTTGTGTTTTCCCTTCTGTTTTCAACCAAATCCTAGAGCCAGCTGAGAC
TGATACGTAACCTGAAGGCTAACACAAGAATGAACCAGGAATGTCAGTTCCTCCTTGGGAGGTT
TGCTGGGTGGTGAAAGATGTAAAATATTACCTTCTCCCTCTTCTCTTGACTTGTATTTTACTGC
ATGTTTTTTTTTTTCATTTTTAATCAATAAAGAGTAAATTGTCCT

hide sequence

RefSeq Acc Id:

XM_063265654 ⟹ XP_063121724

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	127,850,481 - 127,941,518 (-)	NCBI

RefSeq Acc Id:

XM_063265655 ⟹ XP_063121725

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	127,879,805 - 127,941,518 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001101664	(Get FASTA)	NCBI Sequence Viewer
	XP_063121724	(Get FASTA)	NCBI Sequence Viewer
	XP_063121725	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	A0A8I5ZNK2	(Get FASTA)	NCBI Sequence Viewer
	EDL76918	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000018056
	ENSRNOP00000079676.1

RefSeq Acc Id:

NP_001101664 ⟸ NM_001108194

- UniProtKB:

A0A8I5ZZD5 (UniProtKB/Swiss-Prot), D3ZUC9 (UniProtKB/TrEMBL), A6I3V9 (UniProtKB/TrEMBL), A0A8I5ZNK2 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSEDSSALPWSINRDDYELQEVIGSGATAVVQAAYCAPKKERVAIKRINLEKCQTSMDELLKEI
QAMSQCHHPNIVSYYTSFVVKDELWLVMKLLSGGSVLDIIKHIVAKGEHKGGVLDESTIATILR
EVLEGLEYLHKNGQIHRDVKAGNILLGEDGSVQIADFGVSAFLATGGDITRNKVRKTFVGTPCW
MAPEVMEQVRGYDFKADIWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPSLDTGVQDKEM
LKKYGKSFRKMISLCLQKDPEKRPTAAELLRHKFFQKAKNKEFLQEKILQRAPTISERSKKVRR
VPGSSGRLHKTEDGGWEWSDDEFDEESEEGKAAISQLRSPRVKDSLSNSELFSAADPMGTLLQV
PEQISAHLPQPASQMPTQPAQVSLLPPAEPAKPAQARSSGERSQETKVPISLVLRLRNSKKELN
DIRFEFTPGRDTAEGVSQELISAGLVDGRDLVIVAANLQKIVEEPQSNRSVTFKLASGVEGSDI
PDDGKLIGFAQLSIS

hide sequence

Ensembl Acc Id:

ENSRNOP00000018056 ⟸ ENSRNOT00000018056

Ensembl Acc Id:

ENSRNOP00000079676 ⟸ ENSRNOT00000099478

Ensembl Acc Id:

ENSRNOP00000085510 ⟸ ENSRNOT00000108136

RefSeq Acc Id:	XP_063121724 ⟸ XM_063265654
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I5ZZD5 (UniProtKB/Swiss-Prot), A0A8I5ZNK2 (UniProtKB/Swiss-Prot)

RefSeq Acc Id:	XP_063121725 ⟸ XM_063265655
- Peptide Label:	isoform X2

Protein Domains

Protein kinase

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZUC9-F1-model_v2	AlphaFold	D3ZUC9	1-527	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13696368

Promoter ID:

EPDNEW_R6893

Type:

initiation region

Name:

Oxsr1_1

Description:

oxidative-stress responsive 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	8	128,009,916 - 128,009,976	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1310466	AgrOrtholog
BioCyc Gene	G2FUF-28795	BioCyc
Ensembl Genes	ENSRNOG00000013136	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000018056	ENTREZGENE
	ENSRNOT00000099478.1	UniProtKB/Swiss-Prot
Gene3D-CATH	Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1	UniProtKB/Swiss-Prot
	Phosphorylase Kinase, domain 1	UniProtKB/Swiss-Prot
	Transferase(Phosphotransferase) domain 1	UniProtKB/Swiss-Prot
InterPro	Kinase-like_dom_sf	UniProtKB/Swiss-Prot
	Kinase_OSR1/WNK_CCT	UniProtKB/Swiss-Prot
	Prot_kinase_dom	UniProtKB/Swiss-Prot
	Protein_kinase_ATP_BS	UniProtKB/Swiss-Prot
	STE20/SPS1-PAK	UniProtKB/Swiss-Prot
NCBI Gene	316064	ENTREZGENE
PANTHER	SERINE/THREONINE-PROTEIN KINASE OSR1	UniProtKB/Swiss-Prot
	STERILE20-LIKE KINASE, ISOFORM B-RELATED	UniProtKB/Swiss-Prot
Pfam	OSR1_C	UniProtKB/Swiss-Prot
	Pkinase	UniProtKB/Swiss-Prot
PhenoGen	Oxsr1	PhenoGen
PROSITE	PROTEIN_KINASE_ATP	UniProtKB/Swiss-Prot
	PROTEIN_KINASE_DOM	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000013136	RatGTEx
SMART	S_TKc	UniProtKB/Swiss-Prot
Superfamily-SCOP	Protein kinase-like (PK-like)	UniProtKB/Swiss-Prot
UniProt	A0A8I5ZNK2	ENTREZGENE
	A0A8I5ZZD5	ENTREZGENE
	A0A9T0CD43_RAT	UniProtKB/TrEMBL
	A6I3V9	ENTREZGENE, UniProtKB/TrEMBL
	D3ZUC9	ENTREZGENE, UniProtKB/TrEMBL
	OXSR1_RAT	UniProtKB/Swiss-Prot
UniProt Secondary	A0A8I5ZZD5	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2018-11-01	Oxsr1	oxidative stress responsive kinase 1	Oxsr1	oxidative-stress responsive 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	Oxsr1	oxidative-stress responsive 1	Oxsr1_predicted	oxidative-stress responsive 1 (predicted)	'predicted' is removed	2292626	APPROVED
2006-03-30	Oxsr1_predicted	oxidative-stress responsive 1 (predicted)			Symbol and Name updated	1299863	APPROVED
2006-03-28	Oxsr1_predicted		Osr1_predicted	oxidative-stress responsive 1 (predicted)	Symbol updated to reflect Human and Mouse nomenclature	1299863	APPROVED
2005-01-12	Osr1_predicted	oxidative-stress responsive 1 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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