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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of interleukin-1 beta production
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Accession:GO:0032691 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-1 beta production.
Synonyms:exact_synonym: down regulation of interleukin-1 beta production;   downregulation of interleukin-1 beta production;   negative regulation of IL-1 beta production
 narrow_synonym: inhibition of interleukin-1 beta production;   negative regulation of interleukin-1 beta biosynthetic process;   negative regulation of interleukin-1 beta secretion
 alt_id: GO:0050713;   GO:0050724


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negative regulation of interleukin-1 beta production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acp5 acid phosphatase 5, tartrate resistant acts_upstream_of_or_within IMP (PMID:11168643) MGI PMID:11168643 NCBI chr 9:22,038,023...22,047,042
Ensembl chr 9:22,038,023...22,047,007 		JBrowse link
G Apoa1 apolipoprotein A-I involved_in IEA
ISO		 Ensembl
GO_Central		 GO_REF:0000107 GO_REF:0000119 NCBI chr 9:46,139,928...46,141,767
Ensembl chr 9:46,139,878...46,141,764 		JBrowse link
G Aqp4 aquaporin 4 involved_in ISO RGD
GO_Central		 PMID:22449442 GO_REF:0000096 RGD:8695996 NCBI chr18:15,522,451...15,544,039
Ensembl chr18:15,522,553...15,544,039 		JBrowse link
G Arrb2 arrestin, beta 2 involved_in IMP (PMID:16378096) UniProt PMID:16378096 NCBI chr11:70,323,051...70,331,654
Ensembl chr11:70,323,461...70,331,654 		JBrowse link
G Cd33 CD33 molecule involved_in ISO (PMID:15597323) ARUK-UCL PMID:15597323 NCBI chr 7:43,176,823...43,186,679
Ensembl chr 7:43,173,640...43,193,852 		JBrowse link
G Chrna7 cholinergic receptor, nicotinic, alpha polypeptide 7 acts_upstream_of_or_within IMP (PMID:12508119) MGI PMID:12508119 NCBI chr 7:62,748,440...62,862,274
Ensembl chr 7:62,748,440...62,862,317 		JBrowse link
G Cptp ceramide-1-phosphate transfer protein involved_in ISO
IMP		 (PMID:29164996) GO_Central
UniProt		 PMID:29164996 GO_REF:0000119 NCBI chr 4:155,949,180...155,953,897
Ensembl chr 4:155,949,180...155,953,897 		JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 involved_in ISO
IEA		 GO_Central
Ensembl		 GO_REF:0000096 GO_REF:0000107 NCBI chr 9:119,877,749...119,897,362
Ensembl chr 9:119,877,749...119,898,945 		JBrowse link
G Elf4 E74 like ETS transcription factor 4 involved_in IMP
ISO		 (PMID:34326534) UniProt
GO_Central		 PMID:34326534 GO_REF:0000119 NCBI chr  X:47,499,926...47,552,009
Ensembl chr  X:47,499,923...47,552,009 		JBrowse link
G Errfi1 ERBB receptor feedback inhibitor 1 involved_in ISO RGD
GO_Central		 PMID:19204184 GO_REF:0000096 RGD:9685562 NCBI chr 4:150,938,253...150,953,346
Ensembl chr 4:150,938,376...150,953,349 		JBrowse link
G Ffar1 free fatty acid receptor 1 involved_in IEA
ISO		 Ensembl
GO_Central		 GO_REF:0000107 GO_REF:0000119 NCBI chr 7:30,559,993...30,560,895
Ensembl chr 7:30,556,815...30,560,989 		JBrowse link
G Ffar4 free fatty acid receptor 4 involved_in ISO
IEA		 GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 NCBI chr19:38,085,527...38,102,711
Ensembl chr19:38,085,519...38,102,711 		JBrowse link
G Gdnf glial cell line derived neurotrophic factor ISO RGD PMID:32428552 RGD:405878062 NCBI chr15:7,839,529...7,867,061
Ensembl chr15:7,840,327...7,867,056 		JBrowse link
G Ghrl ghrelin involved_in ISO
ISS		 RGD
GO_Central
UniProt		 PMID:19620309 GO_REF:0000024 GO_REF:0000096 GO_REF:0000119 RGD:12905041 NCBI chr 6:113,693,080...113,696,872
Ensembl chr 6:113,693,080...113,696,841 		JBrowse link
G Ghsr growth hormone secretagogue receptor involved_in ISS
ISO		 UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000119 NCBI chr 3:27,425,500...27,433,384
Ensembl chr 3:27,425,500...27,432,159 		JBrowse link
G Git1 GIT ArfGAP 1 involved_in IMP (PMID:32460388) UniProt PMID:32460388 NCBI chr11:77,384,114...77,398,600
Ensembl chr11:77,384,388...77,398,612 		JBrowse link
G Gstp-ps glutathione S-transferase, pi, pseudogene involved_in ISO GO_Central GO_REF:0000119 NCBI chr 1:191,758,036...191,762,461
Ensembl chr 1:191,758,120...191,758,750 		JBrowse link
G Gstp1 glutathione S-transferase, pi 1 involved_in ISO
IDA		 (PMID:18962899) GO_Central
BHF-UCL		 PMID:18962899 GO_REF:0000119 NCBI chr19:4,085,411...4,087,912
Ensembl chr19:4,085,407...4,087,985 		JBrowse link
G Gstp2 glutathione S-transferase, pi 2 involved_in ISO GO_Central GO_REF:0000119 NCBI chr19:4,090,288...4,092,221
Ensembl chr19:4,090,285...4,096,023 		JBrowse link
G Gstp3 glutathione S-transferase pi 3 involved_in ISO GO_Central GO_REF:0000119 NCBI chr19:4,107,470...4,109,587
Ensembl chr19:4,107,477...4,109,569 		JBrowse link
G H19 H19, imprinted maternally expressed transcript ISO RGD PMID:27796346 RGD:156430325 NCBI chr 7:142,129,267...142,131,883
Ensembl chr 7:142,129,262...142,133,957 		JBrowse link
G Igf1 insulin-like growth factor 1 involved_in ISO GO_Central GO_REF:0000119 NCBI chr10:87,694,127...87,772,909
Ensembl chr10:87,694,127...87,772,904 		JBrowse link
G Lilrb4a leukocyte immunoglobulin-like receptor, subfamily B, member 4A involved_in ISO GO_Central GO_REF:0000119 NCBI chr10:51,366,999...51,372,709
Ensembl chr10:51,367,052...51,372,707 		JBrowse link
G Lilrb4b leukocyte immunoglobulin-like receptor, subfamily B, member 4B involved_in ISO GO_Central GO_REF:0000119 NCBI chr10:51,356,757...51,362,417
Ensembl chr10:51,356,728...51,362,799 		JBrowse link
G Mefv Mediterranean fever involved_in ISO GO_Central GO_REF:0000119 NCBI chr16:3,524,838...3,536,073
Ensembl chr16:3,525,082...3,535,961 		JBrowse link
G Mir101a microRNA 101a acts_upstream_of ISO (PMID:26022377) ARUK-UCL PMID:26022377 NCBI chr 4:101,204,142...101,204,224
Ensembl chr 4:101,204,142...101,204,224 		JBrowse link
G Mir101b microRNA 101b acts_upstream_of ISO (PMID:26022377) ARUK-UCL PMID:26022377 NCBI chr19:29,112,679...29,112,775
Ensembl chr19:29,112,679...29,112,775 		JBrowse link
G Mir140 microRNA 140 ISO RGD PMID:31376096 PMID:32519270 RGD:329337378 RGD:329347827 NCBI chr 8:108,277,876...108,277,945
Ensembl chr 8:108,277,876...108,277,945 		JBrowse link
G Mir181a-1 microRNA 181a-1 involved_in ISO (PMID:23516523) ARUK-UCL PMID:23516523 NCBI chr 1:137,894,193...137,894,279
Ensembl chr 1:137,894,193...137,894,279 		JBrowse link
G Mir181a-2 microRNA 181a-2 involved_in ISO (PMID:23516523) ARUK-UCL PMID:23516523 NCBI chr 2:38,742,747...38,742,822
Ensembl chr 2:38,742,747...38,742,822 		JBrowse link
G Mir181d microRNA 181d involved_in ISO (PMID:28389653) ARUK-UCL PMID:28389653 NCBI chr 8:84,905,345...84,905,416
Ensembl chr 8:84,905,345...84,905,416 		JBrowse link
G Mir204 microRNA 204 involved_in ISO (PMID:29441883) ARUK-UCL PMID:29441883 NCBI chr19:22,727,969...22,728,036
Ensembl chr19:22,727,969...22,728,036 		JBrowse link
G Mir223 microRNA 223 ISO RGD PMID:31237865 RGD:25824937 NCBI chr  X:95,286,423...95,286,532
Ensembl chr  X:95,286,423...95,286,532 		JBrowse link
G Mir27b microRNA 27b involved_in ISO (PMID:31124343) ARUK-UCL PMID:31124343 NCBI chr13:63,448,526...63,448,598
Ensembl chr13:63,448,526...63,448,598 		JBrowse link
G Mir488 microRNA 488 involved_in ISO (PMID:28915828) ARUK-UCL PMID:28915828 NCBI chr 1:158,333,195...158,333,303
Ensembl chr 1:158,333,195...158,333,303 		JBrowse link
G Mir708 microRNA 708 acts_upstream_of ISO (PMID:31599428) ARUK-UCL PMID:31599428 NCBI chr 7:95,898,631...95,898,739
Ensembl chr 7:95,898,631...95,898,739 		JBrowse link
G Mir877 microRNA 877 acts_upstream_of ISO (PMID:27542871) ARUK-UCL PMID:27542871 NCBI chr17:36,271,622...36,271,706
Ensembl chr17:36,271,622...36,271,706 		JBrowse link
G Mir98 microRNA 98 acts_upstream_of ISO (PMID:31886314) ARUK-UCL PMID:31886314 NCBI chr  X:150,696,210...150,696,317
Ensembl chr  X:150,696,210...150,696,317 		JBrowse link
G Nlrc3 NLR family, CARD domain containing 3 involved_in IMP (PMID:22863753) CACAO PMID:22863753 NCBI chr16:3,762,871...3,796,881
Ensembl chr16:3,762,871...3,794,496 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 involved_in ISO GO_Central GO_REF:0000119 NCBI chr11:59,432,395...59,457,781
Ensembl chr11:59,432,394...59,457,782 		JBrowse link
G Pml promyelocytic leukemia involved_in IMP (PMID:24407287) AgBase PMID:24407287 NCBI chr 9:58,125,359...58,157,077
Ensembl chr 9:58,125,359...58,157,069 		JBrowse link
G Rad21 RAD21 cohesin complex component involved_in ISO
IEA		 RGD
GO_Central
Ensembl		 PMID:36538854 GO_REF:0000096 GO_REF:0000107 RGD:243065265 NCBI chr15:51,826,000...51,856,934
Ensembl chr15:51,825,636...51,855,143 		JBrowse link
G Serpinb1a serine (or cysteine) peptidase inhibitor, clade B, member 1a involved_in ISO
IMP
IBA		 (PMID:30692621) GO_Central
UniProt		 PMID:30692621 GO_REF:0000033 GO_REF:0000119 NCBI chr13:33,026,075...33,037,189
Ensembl chr13:33,026,075...33,035,168 		JBrowse link
G Serpinb1b serine (or cysteine) peptidase inhibitor, clade B, member 1b involved_in ISO
IMP
IBA		 (PMID:30692621) GO_Central
UniProt		 PMID:30692621 GO_REF:0000033 GO_REF:0000119 NCBI chr13:33,262,478...33,278,363
Ensembl chr13:33,262,558...33,278,363 		JBrowse link
G Serpinb1c serine (or cysteine) peptidase inhibitor, clade B, member 1c involved_in IMP
ISO
IBA		 (PMID:30692621) UniProt
GO_Central		 PMID:30692621 GO_REF:0000033 GO_REF:0000119 NCBI chr13:33,065,201...33,126,773
Ensembl chr13:33,065,417...33,082,194 		JBrowse link
G Spag11a sperm associated antigen 11A acts_upstream_of_or_within IDA (PMID:22535201) MGI PMID:22535201 NCBI chr 8:19,207,229...19,209,936
Ensembl chr 8:19,207,902...19,209,594
Ensembl chr 8:19,207,902...19,209,594 		JBrowse link
G Tnfaip3 tumor necrosis factor, alpha-induced protein 3 acts_upstream_of_or_within
involved_in		 ISO
IMP		 (PMID:28094437)
(PMID:18006655), (PMID:18342009)		 MGI
BHF-UCL		 PMID:18006655 PMID:18342009 PMID:28094437 NCBI chr10:18,876,658...18,891,158
Ensembl chr10:18,876,658...18,891,405 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in IMP (PMID:28592261) UniProt PMID:28592261 NCBI chr17:48,653,429...48,659,304
Ensembl chr17:48,653,429...48,661,175 		JBrowse link
G Zc3h12a zinc finger CCCH type containing 12A involved_in IDA (PMID:21616078) UniProt PMID:21616078 NCBI chr 4:125,012,207...125,021,674
Ensembl chr 4:125,012,216...125,021,633 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28635
    negative regulation of biological process 6093
      negative regulation of multicellular organismal process 1428
        negative regulation of cytokine production 426
          negative regulation of interleukin-1 production 59
            negative regulation of interleukin-1 beta production 49
Path 2
Term Annotations click to browse term
  biological_process 28635
    biological regulation 13450
      regulation of biological process 13009
        regulation of cellular process 12632
          regulation of metabolic process 6975
            regulation of biosynthetic process 5711
              regulation of macromolecule biosynthetic process 5492
                regulation of gene expression 5373
                  regulation of cytokine production 1004
                    regulation of interleukin-1 production 157
                      regulation of interleukin-1 beta production 132
                        negative regulation of interleukin-1 beta production 49
paths to the root