Mir181a-2 (microRNA 181a-2) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Mir181a-2 (microRNA 181a-2) Mus musculus
Analyze
Symbol: Mir181a-2
Name: microRNA 181a-2
RGD ID: 1608315
MGI Page MGI
Description: Acts upstream of or within several processes, including cellular response to leukemia inhibitory factor; cellular response to lipopolysaccharide; and long-term synaptic potentiation. Is expressed in embryo; intermediate grey horn; lower lip; lung; and upper lip. Orthologous to human MIR181A2 (microRNA 181a-2).
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: miR-1; miR-181; mir-181a; mir-181a-2; Mirn; Mirn18; Mirn181; Mirn181a; Mirn181a-2
RGD Orthologs
Human
Rat
Dog
Pig
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39238,742,747 - 38,742,822 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl238,742,747 - 38,742,822 (+)EnsemblGRCm39 Ensembl
GRCm38238,852,735 - 38,852,810 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl238,852,735 - 38,852,810 (+)EnsemblGRCm38mm10GRCm38
MGSCv37238,708,255 - 38,708,330 (+)NCBIGRCm37MGSCv37mm9NCBIm37
Celera240,576,847 - 40,576,922 (+)NCBICelera
Cytogenetic Map2BNCBI
cM Map224.42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12554859   PMID:12624257   PMID:14657504   PMID:15538371   PMID:15634332   PMID:16369549   PMID:16381832   PMID:17251443   PMID:17369397   PMID:17382377   PMID:17604727   PMID:18282110  
PMID:18452032   PMID:18762567   PMID:18974849   PMID:19559694   PMID:19801983   PMID:20215419   PMID:20413612   PMID:20439489   PMID:20558617   PMID:20884876   PMID:21037258   PMID:21267068  
PMID:21822254   PMID:21958558   PMID:22219331   PMID:22476949   PMID:22580216   PMID:22854828   PMID:22956783   PMID:23220232   PMID:23262291   PMID:23589855   PMID:23622242   PMID:23623381  
PMID:23646144   PMID:23650073   PMID:23780685   PMID:24037508   PMID:24416377   PMID:24966929   PMID:24967703   PMID:25024332   PMID:25477247   PMID:25858512   PMID:26062603   PMID:26163591  
PMID:26283154   PMID:27009493   PMID:27089939   PMID:27411504   PMID:27533020   PMID:27802900   PMID:28323882   PMID:28522364   PMID:28597963   PMID:28814760   PMID:28941704   PMID:28947753  
PMID:28968688   PMID:28981116   PMID:29426375   PMID:29567782   PMID:29795190   PMID:29908129   PMID:30900118   PMID:30979712   PMID:31189717   PMID:31682635   PMID:31801413   PMID:31942002  
PMID:32087004   PMID:32291905   PMID:32338107   PMID:32346884   PMID:32427944   PMID:32773582   PMID:33015817   PMID:33360253   PMID:33617143   PMID:33780118   PMID:33966404   PMID:34787641  
PMID:35073549   PMID:35305974   PMID:35810742   PMID:35991122   PMID:36074090   PMID:36463188   PMID:36604945   PMID:36734882   PMID:36797653   PMID:38354943   PMID:38503934   PMID:38783381  


Genomics

Comparative Map Data
Mir181a-2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39238,742,747 - 38,742,822 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl238,742,747 - 38,742,822 (+)EnsemblGRCm39 Ensembl
GRCm38238,852,735 - 38,852,810 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl238,852,735 - 38,852,810 (+)EnsemblGRCm38mm10GRCm38
MGSCv37238,708,255 - 38,708,330 (+)NCBIGRCm37MGSCv37mm9NCBIm37
Celera240,576,847 - 40,576,922 (+)NCBICelera
Cytogenetic Map2BNCBI
cM Map224.42NCBI
MIR181A2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389124,692,442 - 124,692,551 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9124,692,442 - 124,692,551 (+)EnsemblGRCh38hg38GRCh38
GRCh379127,454,721 - 127,454,830 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369126,494,541 - 126,494,650 (+)NCBINCBI36Build 36hg18NCBI36
Celera998,102,607 - 98,102,716 (+)NCBICelera
Cytogenetic Map9q33.3NCBI
HuRef997,067,445 - 97,067,554 (+)NCBIHuRef
CHM1_19127,603,590 - 127,603,699 (+)NCBICHM1_1
T2T-CHM13v2.09136,890,690 - 136,890,799 (+)NCBIT2T-CHM13v2.0
Mir181a2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8343,025,563 - 43,025,679 (+)NCBIGRCr8
mRatBN7.2322,615,845 - 22,615,961 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl322,615,845 - 22,615,961 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx326,084,562 - 26,084,678 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0334,669,555 - 34,669,671 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0332,482,101 - 32,482,217 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0323,150,352 - 23,150,468 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl323,150,352 - 23,150,468 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0328,374,769 - 28,374,885 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera321,049,302 - 21,049,418 (+)NCBICelera
Cytogenetic Map3q12NCBI
MIR181A-2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1958,302,547 - 58,302,606 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl958,302,547 - 58,302,606 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha957,501,180 - 57,501,239 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0959,222,881 - 59,222,940 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl959,222,881 - 59,222,940 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1957,981,720 - 57,981,779 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0958,298,088 - 58,298,147 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0958,388,572 - 58,388,631 (-)NCBIUU_Cfam_GSD_1.0
MIR181A-2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1265,497,249 - 265,497,328 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11265,497,249 - 265,497,328 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21299,322,152 - 299,322,231 (+)NCBISscrofa10.2Sscrofa10.2susScr3

miRNA Target Status

Predicted Targets
Summary Value
Count of predictions:1166
Count of gene targets:854
Count of transcripts:1102
Interacting mature miRNAs:mmu-miR-181a-2-3p
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
8552707Cia23_mcollagen induced arthritis QTL 23 (mouse)Not determined21212953766556453Mouse
12904005Cfq2_mconditioned fear QTL 2 (mouse)22702264256396228Mouse
14746979Manh51_mmandible shape 51 (mouse)22896112962961129Mouse
1300624Insq7_minsulin QTL 7 (mouse)Not determined2938444643384575Mouse
39128209Lwq14_mliver weight QTL 14 (mouse)220897778118894840Mouse
1558738W6q1_mweight 6 weeks QTL 1 (mouse)Not determined220897778118894840Mouse
4142133Pbwg1.6_mpostnatal body weight growth 1.6 (mouse)Not determined3579732469797406Mouse
4141236Hbnr5_mHeligmosomoides bakeri nematode resistance 5 (mouse)Not determined31214567105143570Mouse
26884438Sklq12_mskull length QTL 12, 16 week (mouse)22459001254890012Mouse
12904008Cfq6_mconditioned fear QTL 6 (mouse)23120303544508204Mouse
1301790Pcfm1_mperiosteal circumference and femur length 1 (mouse)Not determined2823629642236396Mouse
1302174Dssc2_mdextran sodium sulfate induced colitis QTL2 (mouse)Not determined224224632148700377Mouse
4142130Pgis2_mproteoglycan induced spondylitis 2 (mouse)Not determined22530805156971811Mouse
1559001Eae33_mexperimental allergic encephalomyelitis susceptibility 33 (mouse)Not determined23599167971609412Mouse
1301980Fcsa5_mfemoral cross-sectional area 5 (mouse)Not determined2767911541679261Mouse
4142447Pbwg1.7_mpostnatal body weight growth 1.7 (mouse)Not determined3579732469797406Mouse
1301376Etohc1_methanol consumption 1 (mouse)Not determined22112972555129871Mouse
1558915W3q1_mweight 3 weeks QTL 1 (mouse)Not determined220897778118894840Mouse
14746997Mancz2_mmandible centroid size 2 (mouse)22896112962961129Mouse
12792980Fbmd1_mfemoral bone mineral density 1, females only (mouse)22503449245034492Mouse
1301769Orgwq2_morgan weight QTL 2 (mouse)Not determined2388712693421651Mouse
1301641Sbmd2_mspinal bone mineral density 2 (mouse)Not determined21421456748214713Mouse
1357454Kidq1_mkidney weight QTL 1 (mouse)Not determined220897778118894840Mouse
10755513Amzn4_manatomical modifier of Zfp423 4 (mouse)2938444643384575Mouse
10449151Hdl8_mhigh density lipoprotein (HDL) level 8 (mouse)23812972567072607Mouse
1558966W10q9_mweight 10 weeks QTL 9 (mouse)Not determined220897778118894840Mouse
4141854T2dm2sa_mtype 2 diabetes mellitus 2 in SMXA RI mice (mouse)Not determined229307947148374934Mouse
10449150Pvldlc1_mplasma VLDL-cholesterol 1 (mouse)23812972567072607Mouse
13463470Tubisq1_mtubulointerstitial injury severity, QTL 1 (mouse)22368914557689269Mouse
1558899Egq1_mearly growth QTL 1 (mouse)Not determined220897778118894840Mouse
1357681Hrtq1_mheart weight QTL 1 (mouse)Not determined220897778118894840Mouse
10449145Lanq1_mlanosterol level QTL 1 (mouse)23812972567072607Mouse
1357436Splq1_mspleen weight QTL 1 (mouse)Not determined220897778118894840Mouse
1357881Estoq1_membryo survival total QTL 1 (mouse)Not determined220897778118894840Mouse
13464253Ifvrq1_minfluenza virus resistance QTL 1 (mouse)23303449252034492Mouse
1300577Capsq1_mcapsaicin sensitivity related QTL 1 (mouse)Not determined22760206084013384Mouse
4141708Pbwg1.2_mpostnatal body weight growth 1.2 (mouse)Not determined2112972555129871Mouse
10043876Adip22_madiposity 22 (mouse)Not determined2830805142308240Mouse
4141186Pbwg1.8_mpostnatal body weight growth 1.8 (mouse)Not determined3579732469797406Mouse


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000083489
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl238,742,747 - 38,742,822 (+)Ensembl
GRCm38.p6 Ensembl238,852,735 - 38,852,810 (+)Ensembl
RefSeq Acc Id: NR_029568
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39238,742,747 - 38,742,822 (+)NCBI
GRCm38238,852,735 - 38,852,810 (+)ENTREZGENE
MGSCv37238,708,255 - 38,708,330 (+)RGD
Celera240,576,847 - 40,576,922 (+)RGD
cM Map2 ENTREZGENE
Sequence:

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2676845 AgrOrtholog
Ensembl Genes ENSMUSG00000065423 Ensembl, ENTREZGENE
Ensembl Transcript ENSMUST00000083489 ENTREZGENE
MGD MGI:2676845 ENTREZGENE
miRBase MI0000223 ENTREZGENE
NCBI Gene 387176 ENTREZGENE
PhenoGen Mir181a-2 PhenoGen
RNAcentral URS000025A61F RNACentral
  URS00003DA300 RNACentral
  URS000075A833 RNACentral