Nlrc3 (NLR family, CARD domain containing 3) - Rat Genome Database

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Gene: Nlrc3 (NLR family, CARD domain containing 3) Mus musculus
Analyze
Symbol: Nlrc3
Name: NLR family, CARD domain containing 3
RGD ID: 1312609
MGI Page MGI
Description: Enables phosphatidylinositol 3-kinase regulatory subunit binding activity. Involved in several processes, including negative regulation of cell population proliferation; negative regulation of cytokine production; and negative regulation of defense response. Acts upstream of or within negative regulation of I-kappaB kinase/NF-kappaB signaling; regulation of protein ubiquitination; and response to lipopolysaccharide. Predicted to be located in centriolar satellite; intracellular membrane-bounded organelle; and perinuclear region of cytoplasm. Predicted to be active in cytosol. Orthologous to human NLRC3 (NLR family CARD domain containing 3).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: caterpillar 16.2; Caterpiller 16.2; CLR16; CLR16.2; D230007K08Rik; FLJ00348; mFLJ00348; MGC161259
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39163,762,871 - 3,796,881 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl163,762,871 - 3,794,496 (-)EnsemblGRCm39 Ensembl
GRCm38163,943,807 - 3,979,017 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl163,945,007 - 3,976,632 (-)EnsemblGRCm38mm10GRCm38
MGSCv37163,946,933 - 3,976,632 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36163,860,235 - 3,891,860 (-)NCBIMGSCv36mm8
Celera164,577,681 - 4,607,937 (-)NCBICelera
Cytogenetic Map16A1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
2. Mouse MP Annotation Import Pipeline RGD automated import pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12477932   PMID:15705585   PMID:16141072   PMID:16141073   PMID:18799693   PMID:21873635   PMID:22863753   PMID:23055939  
PMID:24560620   PMID:26320999   PMID:26410627   PMID:27951586   PMID:28598238   PMID:28731142   PMID:30133544   PMID:30566882   PMID:30893587   PMID:31290162   PMID:32386989   PMID:33425209  
PMID:34335602   PMID:35963285   PMID:36068919  


Genomics

Comparative Map Data
Nlrc3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39163,762,871 - 3,796,881 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl163,762,871 - 3,794,496 (-)EnsemblGRCm39 Ensembl
GRCm38163,943,807 - 3,979,017 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl163,945,007 - 3,976,632 (-)EnsemblGRCm38mm10GRCm38
MGSCv37163,946,933 - 3,976,632 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36163,860,235 - 3,891,860 (-)NCBIMGSCv36mm8
Celera164,577,681 - 4,607,937 (-)NCBICelera
Cytogenetic Map16A1NCBI
NLRC3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38163,539,033 - 3,577,403 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl163,539,033 - 3,577,403 (-)EnsemblGRCh38hg38GRCh38
GRCh37163,589,033 - 3,627,404 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36163,529,034 - 3,567,393 (-)NCBINCBI36Build 36hg18NCBI36
Celera163,795,793 - 3,834,163 (-)NCBICelera
Cytogenetic Map16p13.3NCBI
HuRef163,558,668 - 3,596,656 (-)NCBIHuRef
CHM1_1163,589,077 - 3,627,393 (-)NCBICHM1_1
T2T-CHM13v2.0163,566,292 - 3,604,671 (-)NCBIT2T-CHM13v2.0
Nlrc3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21011,551,378 - 11,585,027 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1011,551,356 - 11,584,398 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01011,809,531 - 11,844,184 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1011,810,926 - 11,842,482 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01010,565,817 - 10,600,272 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41011,828,972 - 11,850,949 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11011,830,270 - 11,850,949 (+)NCBI
Celera1010,507,188 - 10,541,841 (+)NCBICelera
Cytogenetic Map10q12NCBI
Nlrc3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544213,814,434 - 13,833,222 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544213,795,322 - 13,834,362 (+)NCBIChiLan1.0ChiLan1.0
NLRC3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1163,637,607 - 3,674,210 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl163,637,612 - 3,674,088 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0162,463,940 - 2,487,961 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
NLRC3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1637,668,654 - 37,707,387 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl637,647,976 - 37,703,190 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha638,996,730 - 39,036,797 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0637,882,981 - 37,923,068 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl637,883,470 - 37,920,833 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1637,666,136 - 37,706,192 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0637,559,251 - 37,599,498 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0637,969,988 - 38,010,066 (+)NCBIUU_Cfam_GSD_1.0
Nlrc3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344105,935,890 - 105,962,779 (-)NCBIHiC_Itri_2
SpeTri2.0NW_004936694757,121 - 773,924 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NLRC3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl338,687,967 - 38,710,938 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1338,673,590 - 38,719,188 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2340,028,718 - 40,050,697 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NLRC3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.153,241,552 - 3,262,763 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl53,242,242 - 3,262,261 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606827,540,652 - 27,579,410 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nlrc3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248241,357,326 - 1,375,688 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248241,356,587 - 1,375,403 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2063
Count of miRNA genes:480
Interacting mature miRNAs:592
Transcripts:ENSMUST00000096308, ENSMUST00000163478, ENSMUST00000177551, ENSMUST00000180200
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4141060Pbwg19_mpostnatal body weight growth 19 (mouse)Not determined16120780888Mouse
1300632Loca2_mlocomotor activity 2 (mouse)Not determined16122500574Mouse
10043879Adip25_madiposity 25 (mouse)Not determined16122520318Mouse
1301575Tanidd3_mtally ho associated non-insulin dependednt diabetes mellitus 3 (mouse)Not determined16122897739Mouse
4141468Nhdlq10_mnon-HDL QTL 10 (mouse)Not determined16124263853Mouse
1301970Heal11_mwound healing/regeneration 11 (mouse)Not determined16124263853Mouse
1301384Dice1_mdetermination of interleukin 4 commitment 1 (mouse)Not determined16128434358Mouse
10402497Lmr23_mleishmaniasis resistance 23 (mouse)Not determined16129674200Mouse
1301559Bbaa19_mB.burgdorferi-associated arthritis 19 (mouse)Not determined16130066977Mouse
10412289Ppsl_mplasma P-selectin levels (mouse)Not determined16130814572Mouse
27095908Scvln7_msacral vertebrae length 2, 5 week (mouse)16331786439820362Mouse
27226768Tibl9_mtibia length 9, 5 week (mouse)16331786451420363Mouse
27226785Feml12_mfemur length 12, 5 week (mouse)16331786464620363Mouse
1302106Rapop1_mradiation-induced apoptosis 1 (mouse)Not determined16378077915731053Mouse

Markers in Region
D9Mit34.1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map7F1UniSTS
Cytogenetic Map13D1UniSTS
Cytogenetic Map1C3UniSTS
Cytogenetic Map2C1.3UniSTS
Cytogenetic Map19D1UniSTS
Cytogenetic Map9F1UniSTS
Cytogenetic Map1FUniSTS
Cytogenetic Map7D3UniSTS
Cytogenetic Map11E2UniSTS
Cytogenetic Map3F2UniSTS
Cytogenetic Map14C3UniSTS
Cytogenetic Map9A3UniSTS
Cytogenetic Map2H2UniSTS
Cytogenetic Map11E1UniSTS
Cytogenetic Map2H4UniSTS
Cytogenetic Map8B3.3UniSTS
Cytogenetic Map4D1UniSTS
Cytogenetic Map4E2UniSTS
Cytogenetic Map2E5UniSTS
Cytogenetic Map11B4UniSTS
Cytogenetic Map5G3UniSTS
Cytogenetic MapXA5UniSTS
Cytogenetic Map10C1UniSTS
Cytogenetic Map12A1.1UniSTS
Cytogenetic Map6F2UniSTS
Cytogenetic Map1C1.3UniSTS
Cytogenetic Map16B1UniSTS
Cytogenetic Map12C1UniSTS
Cytogenetic Map7E2UniSTS
Cytogenetic Map9F2UniSTS
Cytogenetic Map5FUniSTS
Cytogenetic Map2H1UniSTS
Cytogenetic Map2E2UniSTS
Cytogenetic Map15F1UniSTS
Cytogenetic Map15E1UniSTS
Cytogenetic Map3G2UniSTS
Cytogenetic Map6F3UniSTS
Cytogenetic Map13B3UniSTS
Cytogenetic Map12F1UniSTS
Cytogenetic Map1E4UniSTS
Cytogenetic Map1E3UniSTS
Cytogenetic Map5E1UniSTS
Cytogenetic Map7F3UniSTS
Cytogenetic Map16B3UniSTS
Cytogenetic Map14D2UniSTS
Cytogenetic Map19C2UniSTS
Cytogenetic Map19D3UniSTS
Cytogenetic Map1H5UniSTS
Cytogenetic Map1DUniSTS
Cytogenetic Map14BUniSTS
Cytogenetic Map11CUniSTS
Cytogenetic Map10B4UniSTS
Cytogenetic Map6G3UniSTS
Cytogenetic Map7A1UniSTS
Cytogenetic Map7A3UniSTS
Cytogenetic Map8E1UniSTS
Cytogenetic Map8A2UniSTS
Cytogenetic Map4D3UniSTS
Cytogenetic Map2BUniSTS
Cytogenetic Map5A3UniSTS
Cytogenetic Map9DUniSTS
Cytogenetic Map5C1UniSTS
Cytogenetic Map19C3UniSTS
Cytogenetic Map13A2-A3UniSTS
Cytogenetic Map4C6UniSTS
Cytogenetic Map17DUniSTS
Cytogenetic Map17B1UniSTS
Cytogenetic Map17A3.3UniSTS
Cytogenetic Map13A1UniSTS
Cytogenetic Map3F2.1UniSTS
Cytogenetic Map15D3UniSTS
Cytogenetic Map8D2UniSTS
Cytogenetic Map12A3UniSTS
Cytogenetic Map1H2.1UniSTS
Cytogenetic Map7F5UniSTS
Cytogenetic Map7CUniSTS
Cytogenetic Map2E1UniSTS
Cytogenetic Map11B2UniSTS
Cytogenetic Map16A3UniSTS
Cytogenetic Map5C3.3UniSTS
Cytogenetic Map16A1UniSTS
Cytogenetic Map5G1UniSTS
Cytogenetic Map6A2UniSTS
Cytogenetic Map7B1UniSTS
Cytogenetic Map3F2.2UniSTS
Cytogenetic Map5C3.1UniSTS
Cytogenetic Map2C3UniSTS
Cytogenetic Map17A3.2-A3.3UniSTS
Cytogenetic Map6E3UniSTS
Cytogenetic Map11B1.1UniSTS
Cytogenetic Map1H6UniSTS
Cytogenetic Map2C2UniSTS
Cytogenetic Map19CUniSTS
Cytogenetic Map17E1.3UniSTS
Cytogenetic Map5A1UniSTS
Cytogenetic Map11B5UniSTS
Cytogenetic Map9A5.2UniSTS
Cytogenetic Map1A1UniSTS
Cytogenetic Map13A5UniSTS
Cytogenetic MapXA1.1UniSTS
Cytogenetic Map4D2.3UniSTS
Cytogenetic Map4B3UniSTS
Cytogenetic Map3A3UniSTS
Cytogenetic Map2A3UniSTS
Cytogenetic Map8CUniSTS
Cytogenetic Map12EUniSTS
Cytogenetic Map10C2UniSTS
Cytogenetic Map5G2UniSTS
Cytogenetic Map5B1UniSTS
Cytogenetic Map3F1UniSTS
Cytogenetic Map2H3UniSTS
Cytogenetic Map2A1UniSTS
Cytogenetic Map1H1UniSTS
Cytogenetic Map15F3UniSTS
Cytogenetic Map9E1UniSTS
Cytogenetic Map9CUniSTS
Cytogenetic Map1A2UniSTS
Cytogenetic Map12C3UniSTS
Cytogenetic Map19AUniSTS
Cytogenetic Map5B2UniSTS
Cytogenetic Map3DUniSTS
Cytogenetic Map11B1.3UniSTS
Cytogenetic Map6B1UniSTS
Cytogenetic MapXC-DUniSTS
Cytogenetic Map5G1.3UniSTS
Cytogenetic Map7D1-E2UniSTS
Cytogenetic Map11A1UniSTS
Cytogenetic Map13B1UniSTS
Cytogenetic Map1H2.2UniSTS
Cytogenetic Map8C3UniSTS
Cytogenetic Map11DUniSTS
Cytogenetic MapXA7.3UniSTS
Cytogenetic Map16C1.1UniSTS
Cytogenetic Map15F2UniSTS
Cytogenetic Map9A2UniSTS
Cytogenetic Map1H4-H6UniSTS
Cytogenetic Map12D2UniSTS
Cytogenetic Map1G3UniSTS
Cytogenetic Map5E5UniSTS
Cytogenetic Map1H3UniSTS
Cytogenetic Map19BUniSTS
cM Map950.0UniSTS
Whitehead Genetic943.7UniSTS
PMC133845P3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381739,847,174 - 39,847,525UniSTSGRCm38
MGSCv371739,984,119 - 39,984,470UniSTSGRCm37
Cytogenetic Map5G2UniSTS
Cytogenetic Map16A1UniSTS
Cytogenetic Map17B1UniSTS
PMC152246P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381739,847,352 - 39,847,428UniSTSGRCm38
GRCm3863,201,441 - 3,201,517UniSTSGRCm38
MGSCv3763,151,441 - 3,151,517UniSTSGRCm37
MGSCv371739,984,297 - 39,984,373UniSTSGRCm37
Celera63,343,461 - 3,343,537UniSTS
Cytogenetic Map16A1UniSTS
Cytogenetic Map5G2UniSTS
Cytogenetic Map17B1UniSTS
D16Mit32  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38163,962,915 - 3,963,024UniSTSGRCm38
MGSCv37163,962,915 - 3,963,024UniSTSGRCm37
Celera164,594,220 - 4,594,329UniSTS
Cytogenetic Map16A1UniSTS
cM Map161.7UniSTS
Whitehead Genetic160.0UniSTS
Whitehead/MRC_RH1610.87UniSTS
Whitehead_YAC16 UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001081280 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_175547 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006522150 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011245902 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011245903 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011245906 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030249119 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030249120 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030249121 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036159931 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_875809 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC087900 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC129021 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK079766 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK084199 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK171971 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC130223 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC152543 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BK005605 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000096308
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl163,766,734 - 3,794,496 (-)Ensembl
GRCm38.p6 Ensembl163,948,870 - 3,976,632 (-)Ensembl
RefSeq Acc Id: ENSMUST00000163478
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl163,766,743 - 3,782,071 (-)Ensembl
GRCm38.p6 Ensembl163,948,879 - 3,964,207 (-)Ensembl
RefSeq Acc Id: ENSMUST00000177551   ⟹   ENSMUSP00000137628
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl163,763,474 - 3,794,496 (-)Ensembl
GRCm38.p6 Ensembl163,945,610 - 3,976,632 (-)Ensembl
RefSeq Acc Id: ENSMUST00000180200   ⟹   ENSMUSP00000137325
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl163,762,871 - 3,794,409 (-)Ensembl
GRCm38.p6 Ensembl163,945,007 - 3,976,545 (-)Ensembl
RefSeq Acc Id: ENSMUST00000229884   ⟹   ENSMUSP00000155241
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl163,764,230 - 3,783,504 (-)Ensembl
GRCm38.p6 Ensembl163,946,366 - 3,965,640 (-)Ensembl
RefSeq Acc Id: NM_001081280   ⟹   NP_001074749
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39163,762,871 - 3,794,496 (-)NCBI
GRCm38163,945,007 - 3,976,632 (-)NCBI
MGSCv37163,946,933 - 3,976,632 (-)RGD
Celera164,577,681 - 4,607,937 (-)RGD
cM Map16 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_175547   ⟹   NP_780756
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39163,762,871 - 3,794,496 (-)NCBI
GRCm38163,945,007 - 3,976,632 (-)NCBI
Celera164,577,681 - 4,607,937 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006522150   ⟹   XP_006522213
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39163,777,255 - 3,796,881 (-)NCBI
GRCm38163,959,391 - 3,979,017 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011245902   ⟹   XP_011244204
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39163,764,186 - 3,796,881 (-)NCBI
GRCm38163,943,807 - 3,979,017 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011245903   ⟹   XP_011244205
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39163,764,186 - 3,796,881 (-)NCBI
GRCm38163,943,807 - 3,979,017 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011245906   ⟹   XP_011244208
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39163,764,186 - 3,796,881 (-)NCBI
GRCm38163,943,807 - 3,976,420 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030249119   ⟹   XP_030104979
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39163,764,186 - 3,796,881 (-)NCBI
GRCm38163,943,807 - 3,979,017 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030249120   ⟹   XP_030104980
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39163,764,186 - 3,796,881 (-)NCBI
GRCm38163,943,807 - 3,979,017 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030249121   ⟹   XP_030104981
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39163,764,186 - 3,796,881 (-)NCBI
GRCm38163,943,807 - 3,979,017 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036159931   ⟹   XP_036015824
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39163,772,420 - 3,796,881 (-)NCBI
Sequence:
RefSeq Acc Id: XR_875809
RefSeq Status:
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39163,766,768 - 3,796,881 (-)NCBI
GRCm38163,943,807 - 3,979,017 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_001074749   ⟸   NM_001081280
- Peptide Label: isoform 1
- UniProtKB: J3QQ49 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006522213   ⟸   XM_006522150
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_011244208   ⟸   XM_011245906
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_011244205   ⟸   XM_011245903
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_011244204   ⟸   XM_011245902
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: NP_780756   ⟸   NM_175547
- Peptide Label: isoform 2
- UniProtKB: Q5DU56 (UniProtKB/Swiss-Prot),   A0A8C6N334 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_030104981   ⟸   XM_030249121
- Peptide Label: isoform X8
RefSeq Acc Id: XP_030104980   ⟸   XM_030249120
- Peptide Label: isoform X7
RefSeq Acc Id: XP_030104979   ⟸   XM_030249119
- Peptide Label: isoform X6
RefSeq Acc Id: ENSMUSP00000137628   ⟸   ENSMUST00000177551
RefSeq Acc Id: ENSMUSP00000155241   ⟸   ENSMUST00000229884
RefSeq Acc Id: ENSMUSP00000137325   ⟸   ENSMUST00000180200
RefSeq Acc Id: XP_036015824   ⟸   XM_036159931
- Peptide Label: isoform X3
Protein Domains
NACHT

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5DU56-F1-model_v2 AlphaFold Q5DU56 1-1064 view protein structure

Promoters
RGD ID:6827322
Promoter ID:MM_KWN:19947
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   Brain,   Kidney,   Spleen
Transcripts:ENSMUST00000096308,   NM_001081280,   UC007XZD.1,   UC007XZE.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36163,976,221 - 3,977,572 (-)MPROMDB
RGD ID:8685316
Promoter ID:EPDNEW_M20688
Type:initiation region
Name:Nlrc3_1
Description:Mus musculus NLR family, CARD domain containing 3 , transcriptvariant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38163,976,554 - 3,976,614EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2444070 AgrOrtholog
Ensembl Genes ENSMUSG00000049871 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000137325 ENTREZGENE
  ENSMUSP00000137325.2 UniProtKB/Swiss-Prot
  ENSMUSP00000137628 ENTREZGENE
  ENSMUSP00000137628.2 UniProtKB/TrEMBL
  ENSMUSP00000155241.2 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000177551 ENTREZGENE
  ENSMUST00000177551.2 UniProtKB/TrEMBL
  ENSMUST00000180200 ENTREZGENE
  ENSMUST00000180200.8 UniProtKB/Swiss-Prot
  ENSMUST00000229884.2 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.80.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Leu-rich_rpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LRR_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NACHT_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NLRC_HD2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NOD2_WH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:268857 UniProtKB/Swiss-Prot
MGD MGI:2444070 ENTREZGENE
NCBI Gene 268857 ENTREZGENE
PANTHER NACHT, LRR AND CARD DOMAINS-CONTAINING UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam LRR_6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NACHT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NLRC4_HD2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NOD2_WH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Nlrc3 PhenoGen
PROSITE NACHT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART LRR_RI UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP RNI-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF52540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A2R8VHN0_MOUSE UniProtKB/TrEMBL
  A0A8C6N334 ENTREZGENE
  I7LRG7_MOUSE UniProtKB/TrEMBL
  J3QQ49 ENTREZGENE, UniProtKB/TrEMBL
  NLRC3_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary A1L3P6 UniProtKB/Swiss-Prot
  Q3TAB7 UniProtKB/Swiss-Prot
  Q8BJF4 UniProtKB/Swiss-Prot
  Q8BV65 UniProtKB/Swiss-Prot