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Gene: Trem2 (triggering receptor expressed on myeloid cells 2) Mus musculus
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Symbol: Trem2
Name: triggering receptor expressed on myeloid cells 2
Description: Exhibits several functions, including lipopolysaccharide binding activity; lipoteichoic acid binding activity; and peptidoglycan binding activity. Involved in several processes, including glial cell activation; positive regulation of intracellular signal transduction; and response to bacterium. Localizes to the integral component of plasma membrane. Used to study frontotemporal dementia. Is expressed in central nervous system; embryo mesenchyme; genitourinary system; and limb interdigital region. Orthologous to human TREM2 (triggering receptor expressed on myeloid cells 2).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: TREM-2; Trem2a; Trem2b; Trem2c; triggering receptor expressed on monocytes 2; triggering receptor expressed on myeloid cells 2a; triggering receptor expressed on myeloid cells 2b; triggering receptor expressed on myeloid cells 2c
Orthologs:
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm381748,346,401 - 48,352,276 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371748,485,726 - 48,491,598 (+)NCBIGRCm37mm9NCBIm37
MGSCv361747,811,968 - 47,817,840 (+)NCBImm8
Celera1751,775,275 - 51,781,150 (+)NCBICelera
Cytogenetic Map17 CNCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Trem2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1320402
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.