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lung large cell carcinoma - Ontology Report - Rat Genome Database

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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:lung large cell carcinoma
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Accession:DOID:4556 term browser browse the term
Synonyms:exact_synonym: large cell carcinoma of lung
 narrow_synonym: Lymphoepithelioma-Like Lung Carcinoma
 xref: EFO:0003050;   EFO:1000016;   EFO:1000340;   NCI:C4450
For additional species annotation, visit the Alliance of Genome Resources.

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lung large cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G N Arhgap44 Rho GTPase activating protein 44 ISO mRNA:decreased expression:lung (human) RGD PMID:28527113 RGD:401901290 NCBI chrNW_004624877:662,595...851,762
Ensembl chrNW_004624877:661,998...850,431 		JBrowse link
G G ARHGAP44 Rho GTPase activating protein 44 ISO mRNA:decreased expression:lung (human) RGD PMID:28527113 RGD:401901290 NCBI chr16:12,125,543...12,328,203
Ensembl chr16:12,125,574...12,330,501 		JBrowse link
G P ARHGAP44 Rho GTPase activating protein 44 ISO mRNA:decreased expression:lung (human) RGD PMID:28527113 RGD:401901290 NCBI chr12:57,049,900...57,206,706
Ensembl chr12:57,049,895...57,206,889 		JBrowse link
G S Arhgap44 Rho GTPase activating protein 44 ISO mRNA:decreased expression:lung (human) RGD PMID:28527113 RGD:401901290 NCBI chrNW_004936595:5,373,645...5,542,915
Ensembl chrNW_004936595:5,373,476...5,543,073 		JBrowse link
G D ARHGAP44 Rho GTPase activating protein 44 ISO mRNA:decreased expression:lung (human) RGD PMID:28527113 RGD:401901290 NCBI chr 5:36,790,059...36,957,932
Ensembl chr 5:36,789,814...36,957,411 		JBrowse link
G B ARHGAP44 Rho GTPase activating protein 44 ISO mRNA:decreased expression:lung (human) RGD PMID:28527113 RGD:401901290 NCBI chr17:38,657,824...38,859,591
Ensembl chr17:43,357,438...43,453,457 		JBrowse link
G C Arhgap44 Rho GTPase activating protein 44 ISO mRNA:decreased expression:lung (human) RGD PMID:28527113 RGD:401901290 NCBI chrNW_004955467:4,428,738...4,590,877
Ensembl chrNW_004955467:4,430,087...4,522,611 		JBrowse link
G R Arhgap44 Rho GTPase activating protein 44 ISO mRNA:decreased expression:lung (human) RGD PMID:28527113 RGD:401901290 NCBI chr10:50,154,724...50,322,027
Ensembl chr10:49,655,584...49,824,297 		JBrowse link
G M Arhgap44 Rho GTPase activating protein 44 ISO mRNA:decreased expression:lung (human) RGD PMID:28527113 RGD:401901290 NCBI chr11:64,892,865...65,053,779
Ensembl chr11:64,892,865...65,053,787 		JBrowse link
G H ARHGAP44 Rho GTPase activating protein 44 HEP mRNA:decreased expression:lung (human) RGD PMID:28527113 RGD:401901290 NCBI chr17:12,789,498...12,991,643
Ensembl chr17:12,789,498...12,991,643 		JBrowse link
G N Chrna5 cholinergic receptor nicotinic alpha 5 subunit ISO mRNA:increased expression:lung RGD PMID:20124469 RGD:150527851 NCBI chrNW_004624894:2,357,193...2,400,699 JBrowse link
G G CHRNA5 cholinergic receptor nicotinic alpha 5 subunit ISO mRNA:increased expression:lung RGD PMID:20124469 RGD:150527851 NCBI chr26:4,747,734...4,779,231
Ensembl chr26:4,749,766...4,776,822 		JBrowse link
G P CHRNA5 cholinergic receptor nicotinic alpha 5 subunit ISO mRNA:increased expression:lung RGD PMID:20124469 RGD:150527851 NCBI chr 7:47,382,860...47,425,871
Ensembl chr 7:47,383,792...47,425,841 		JBrowse link
G S Chrna5 cholinergic receptor nicotinic alpha 5 subunit ISO mRNA:increased expression:lung RGD PMID:20124469 RGD:150527851 NCBI chrNW_004936471:36,451,070...36,492,774
Ensembl chrNW_004936471:36,452,965...36,492,618 		JBrowse link
G D CHRNA5 cholinergic receptor nicotinic alpha 5 subunit ISO mRNA:increased expression:lung RGD PMID:20124469 RGD:150527851 NCBI chr13:38,343,966...38,355,534
Ensembl chr13:38,346,104...38,355,468 		JBrowse link
G B CHRNA5 cholinergic receptor nicotinic alpha 5 subunit ISO mRNA:increased expression:lung RGD PMID:20124469 RGD:150527851 NCBI chr15:57,493,730...57,530,463
Ensembl chr15:76,455,165...76,486,376 		JBrowse link
G C Chrna5 cholinergic receptor nicotinic alpha 5 subunit ISO mRNA:increased expression:lung RGD PMID:20124469 RGD:150527851 NCBI chrNW_004955450:945,400...974,129
Ensembl chrNW_004955450:946,898...974,457 		JBrowse link
G R Chrna5 cholinergic receptor nicotinic alpha 5 subunit ISO mRNA:increased expression:lung RGD PMID:20124469 RGD:150527851 NCBI chr 8:64,265,879...64,294,233
Ensembl chr 8:55,369,794...55,398,146 		JBrowse link
G M Chrna5 cholinergic receptor, nicotinic, alpha polypeptide 5 ISO mRNA:increased expression:lung RGD PMID:20124469 RGD:150527851 NCBI chr 9:54,888,112...54,918,704
Ensembl chr 9:54,888,164...54,915,063 		JBrowse link
G H CHRNA5 cholinergic receptor nicotinic alpha 5 subunit IEP mRNA:increased expression:lung RGD PMID:20124469 RGD:150527851 NCBI chr15:78,565,520...78,595,269
Ensembl chr15:78,565,520...78,595,269 		JBrowse link
G N Dll4 delta like canonical Notch ligand 4 treatment ISO RGD PMID:33628824 RGD:155663482 NCBI chrNW_004624804:8,179,729...8,189,001
Ensembl chrNW_004624804:8,179,731...8,191,284 		JBrowse link
G G DLL4 delta like canonical Notch ligand 4 treatment ISO RGD PMID:33628824 RGD:155663482 NCBI chr26:42,056,473...42,066,283
Ensembl chr26:42,056,331...42,065,828 		JBrowse link
G P DLL4 delta like canonical Notch ligand 4 treatment ISO RGD PMID:33628824 RGD:155663482 NCBI chr 1:130,376,720...130,386,411
Ensembl chr 1:130,376,721...130,386,411 		JBrowse link
G S Dll4 delta like canonical Notch ligand 4 treatment ISO RGD PMID:33628824 RGD:155663482 NCBI chrNW_004936471:4,320,235...4,330,251
Ensembl chrNW_004936471:4,320,933...4,330,253 		JBrowse link
G D DLL4 delta like canonical Notch ligand 4 treatment ISO RGD PMID:33628824 RGD:155663482 NCBI chr30:8,059,463...8,068,742
Ensembl chr30:8,059,512...8,067,940 		JBrowse link
G B DLL4 delta like canonical Notch ligand 4 treatment ISO RGD PMID:33628824 RGD:155663482 NCBI chr15:19,871,584...19,881,817
Ensembl chr15:38,121,574...38,129,471 		JBrowse link
G C Dll4 delta like canonical Notch ligand 4 treatment ISO RGD PMID:33628824 RGD:155663482 NCBI chrNW_004955416:7,807,049...7,816,346
Ensembl chrNW_004955416:7,807,049...7,817,420 		JBrowse link
G R Dll4 delta like canonical Notch ligand 4 treatment IEP RGD PMID:33628824 RGD:155663482 NCBI chr 3:126,770,945...126,780,769
Ensembl chr 3:106,316,986...106,326,931 		JBrowse link
G M Dll4 delta like canonical Notch ligand 4 treatment ISO RGD PMID:33628824 RGD:155663482 NCBI chr 2:119,156,286...119,166,145
Ensembl chr 2:119,156,265...119,166,443 		JBrowse link
G H DLL4 delta like canonical Notch ligand 4 treatment ISO RGD PMID:33628824 RGD:155663482 NCBI chr15:40,929,340...40,939,073
Ensembl chr15:40,929,340...40,939,073 		JBrowse link
G N Notch1 notch receptor 1 treatment ISO RGD PMID:33628824 RGD:155663482 NCBI chrNW_004624760:1,636,331...1,676,398
Ensembl chrNW_004624760:1,634,702...1,676,531 		JBrowse link
G G NOTCH1 notch receptor 1 treatment ISO RGD PMID:33628824 RGD:155663482 NCBI chr12:1,656,815...1,707,566
Ensembl chr12:1,656,918...1,709,585 		JBrowse link
G P NOTCH1 notch receptor 1 treatment ISO RGD PMID:33628824 RGD:155663482
G S Notch1 notch receptor 1 treatment ISO RGD PMID:33628824 RGD:155663482 NCBI chrNW_004936669:1,292,016...1,334,061
Ensembl chrNW_004936669:1,292,088...1,332,428 		JBrowse link
G D NOTCH1 notch receptor 1 treatment ISO RGD PMID:33628824 RGD:155663482 NCBI chr 9:48,975,972...49,018,985
Ensembl chr 9:48,974,757...49,017,277 		JBrowse link
G B NOTCH1 notch receptor 1 treatment ISO RGD PMID:33628824 RGD:155663482 NCBI chr 9:107,568,670...107,621,032
Ensembl chr 9:136,544,639...136,598,740 		JBrowse link
G C Notch1 notch receptor 1 treatment ISO RGD PMID:33628824 RGD:155663482 NCBI chrNW_004955513:4,225,939...4,264,875
Ensembl chrNW_004955513:4,225,956...4,263,259 		JBrowse link
G R Notch1 notch receptor 1 treatment IEP RGD PMID:33628824 RGD:155663482 NCBI chr 3:29,676,040...29,721,613
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
G M Notch1 notch 1 treatment ISO RGD PMID:33628824 RGD:155663482 NCBI chr 2:26,347,914...26,393,834
Ensembl chr 2:26,347,915...26,406,675 		JBrowse link
G H NOTCH1 notch receptor 1 treatment ISO RGD PMID:33628824 RGD:155663482 NCBI chr 9:136,494,433...136,546,048
Ensembl chr 9:136,494,433...136,546,048 		JBrowse link
G N Ptpn13 protein tyrosine phosphatase non-receptor type 13 ISO mRNA,protein:decreased expression:lung RGD PMID:22245727 RGD:152176663 NCBI chrNW_004624872:3,183,381...3,406,339
Ensembl chrNW_004624872:3,226,000...3,405,805 		JBrowse link
G G PTPN13 protein tyrosine phosphatase non-receptor type 13 ISO mRNA,protein:decreased expression:lung RGD PMID:22245727 RGD:152176663 NCBI chr 7:34,974,028...35,200,214
Ensembl chr 7:34,974,082...35,200,293 		JBrowse link
G P PTPN13 protein tyrosine phosphatase non-receptor type 13 ISO mRNA,protein:decreased expression:lung RGD PMID:22245727 RGD:152176663 NCBI chr 8:132,035,170...132,200,425
Ensembl chr 8:132,035,151...132,249,411 		JBrowse link
G S Ptpn13 protein tyrosine phosphatase non-receptor type 13 ISO mRNA,protein:decreased expression:lung RGD PMID:22245727 RGD:152176663 NCBI chrNW_004936920:313,762...510,334
Ensembl chrNW_004936920:313,814...510,001 		JBrowse link
G D PTPN13 protein tyrosine phosphatase non-receptor type 13 ISO mRNA,protein:decreased expression:lung RGD PMID:22245727 RGD:152176663 NCBI chr32:10,125,447...10,328,764
Ensembl chr32:10,125,441...10,328,757 		JBrowse link
G B PTPN13 protein tyrosine phosphatase non-receptor type 13 ISO mRNA,protein:decreased expression:lung RGD PMID:22245727 RGD:152176663 NCBI chr 4:78,893,598...79,118,745
Ensembl chr 4:89,623,271...89,847,616 		JBrowse link
G C Ptpn13 protein tyrosine phosphatase non-receptor type 13 ISO mRNA,protein:decreased expression:lung RGD PMID:22245727 RGD:152176663 NCBI chrNW_004955474:2,988,109...3,140,520
Ensembl chrNW_004955474:2,988,639...3,140,513 		JBrowse link
G R Ptpn13 protein tyrosine phosphatase, non-receptor type 13 ISO mRNA,protein:decreased expression:lung RGD PMID:22245727 RGD:152176663 NCBI chr14:6,412,841...6,587,238
Ensembl chr14:6,108,211...6,282,563 		JBrowse link
G M Ptpn13 protein tyrosine phosphatase, non-receptor type 13 ISO mRNA,protein:decreased expression:lung RGD PMID:22245727 RGD:152176663 NCBI chr 5:103,573,058...103,746,227
Ensembl chr 5:103,573,058...103,746,169 		JBrowse link
G H PTPN13 protein tyrosine phosphatase non-receptor type 13 IEP mRNA,protein:decreased expression:lung RGD PMID:22245727 RGD:152176663 NCBI chr 4:86,594,315...86,815,161
Ensembl chr 4:86,594,315...86,815,171 		JBrowse link
G N Ttr transthyretin ISO protein:increased expression:lung (human) RGD PMID:26943652 RGD:151665207 NCBI chrNW_004624770:1,255,401...1,262,019
Ensembl chrNW_004624770:1,251,716...1,262,213 		JBrowse link
G G TTR transthyretin ISO protein:increased expression:lung (human) RGD PMID:26943652 RGD:151665207 NCBI chr18:49,124,302...49,131,495
Ensembl chr18:49,124,121...49,131,399 		JBrowse link
G P TTR transthyretin ISO protein:increased expression:lung (human) RGD PMID:26943652 RGD:151665207 NCBI chr 6:115,496,338...115,503,974
Ensembl chr 6:115,496,326...115,503,977 		JBrowse link
G S Ttr transthyretin ISO protein:increased expression:lung (human) RGD PMID:26943652 RGD:151665207 NCBI chrNW_004936682:1,628,489...1,635,495
Ensembl chrNW_004936682:1,628,341...1,635,566 		JBrowse link
G D TTR transthyretin ISO protein:increased expression:lung (human) RGD PMID:26943652 RGD:151665207 NCBI chr 7:57,940,354...57,947,084
Ensembl chr 7:57,914,381...57,947,058 		JBrowse link
G B TTR transthyretin ISO protein:increased expression:lung (human) RGD PMID:26943652 RGD:151665207 NCBI chr18:24,809,707...24,816,713
Ensembl chr18:28,407,893...28,414,960 		JBrowse link
G C Ttr transthyretin ISO protein:increased expression:lung (human) RGD PMID:26943652 RGD:151665207 NCBI chrNW_004955402:18,921,235...18,927,976
Ensembl chrNW_004955402:18,921,274...18,928,108 		JBrowse link
G R Ttr transthyretin ISO protein:increased expression:lung (human) RGD PMID:26943652 RGD:151665207 NCBI chr18:12,216,684...12,225,972
Ensembl chr18:11,943,789...11,951,008 		JBrowse link
G M Ttr transthyretin ISO protein:increased expression:lung (human) RGD PMID:26943652 RGD:151665207 NCBI chr18:20,797,266...20,807,383
Ensembl chr18:20,798,337...20,807,378 		JBrowse link
G H TTR transthyretin HEP protein:increased expression:lung (human) RGD PMID:26943652 RGD:151665207 NCBI chr18:31,591,877...31,598,821
Ensembl chr18:31,557,009...31,598,833 		JBrowse link
large cell neuroendocrine carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G N Slc7a5 solute carrier family 7 member 5 disease_progression ISO RGD PMID:18440724 RGD:151361285 NCBI chrNW_004624746:1,325,368...1,349,616 JBrowse link
G G SLC7A5 solute carrier family 7 member 5 disease_progression ISO RGD PMID:18440724 RGD:151361285 NCBI chr 5:73,229,953...73,269,801
Ensembl chr 5:73,229,951...73,269,754 		JBrowse link
G P SLC7A5 solute carrier family 7 member 5 disease_progression ISO RGD PMID:18440724 RGD:151361285 NCBI chr 6:1,545,940...1,574,298
Ensembl chr 6:1,545,944...1,574,285 		JBrowse link
G S Slc7a5 solute carrier family 7 member 5 disease_progression ISO RGD PMID:18440724 RGD:151361285 NCBI chrNW_004936641:1,513,110...1,538,955 JBrowse link
G D SLC7A5 solute carrier family 7 member 5 disease_progression ISO RGD PMID:18440724 RGD:151361285 NCBI chr 5:65,313,105...65,343,858
Ensembl chr 5:65,313,105...65,343,858 		JBrowse link
G B SLC7A5 solute carrier family 7 member 5 disease_progression ISO RGD PMID:18440724 RGD:151361285 NCBI chr16:68,512,407...68,552,763 JBrowse link
G C Slc7a5 solute carrier family 7 member 5 disease_progression ISO RGD PMID:18440724 RGD:151361285 NCBI chrNW_004955541:2,103,437...2,129,668
Ensembl chrNW_004955541:2,103,384...2,130,310 		JBrowse link
G R Slc7a5 solute carrier family 7 member 5 disease_progression ISO RGD PMID:18440724 RGD:151361285 NCBI chr19:66,843,808...66,872,412
Ensembl chr19:49,935,220...49,963,823 		JBrowse link
G M Slc7a5 solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 disease_progression ISO RGD PMID:18440724 RGD:151361285 NCBI chr 8:122,607,885...122,634,425
Ensembl chr 8:122,607,889...122,634,433 		JBrowse link
G H SLC7A5 solute carrier family 7 member 5 disease_progression IEP RGD PMID:18440724 RGD:151361285 NCBI chr16:87,830,023...87,869,507
Ensembl chr16:87,830,016...87,869,507 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 288179
    disease of cellular proliferation 92555
      Neoplasms by Histologic Type 64893
        cell type cancer 46359
          carcinoma 39822
            large cell carcinoma 112
              lung large cell carcinoma 70
                large cell carcinoma with rhabdoid phenotype 0
                large cell neuroendocrine carcinoma + 10
                lung giant cell carcinoma 0
                lung occult large cell carcinoma 0
                pulmonary large cell neuroendocrine carcinoma + 0
Path 2
Term Annotations click to browse term
  disease 288179
    disease of anatomical entity 271815
      respiratory system disease 65925
        thoracic disease 47582
          Thoracic Neoplasms 10916
            Respiratory Tract Neoplasms 10890
              respiratory system cancer 8841
                lung cancer 8555
                  bronchus cancer 7063
                    bronchus carcinoma 7063
                      lung non-small cell carcinoma 6633
                        lung large cell carcinoma 70
                          large cell carcinoma with rhabdoid phenotype 0
                          large cell neuroendocrine carcinoma + 10
                          lung giant cell carcinoma 0
                          lung occult large cell carcinoma 0
                          pulmonary large cell neuroendocrine carcinoma + 0
paths to the root