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ONTOLOGY REPORT - ANNOTATIONS


Term:midazolam
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Accession:CHEBI:6931 term browser browse the term
Definition:An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.
Synonyms:exact_synonym: 8-chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine
 related_synonym: Dormicum;   Formula=C18H13ClFN3;   InChI=1S/C18H13ClFN3/c1-11-21-9-13-10-22-18(14-4-2-3-5-16(14)20)15-8-12(19)6-7-17(15)23(11)13/h2-9H,10H2,1H3;   InChIKey=DDLIGBOFAVUZHB-UHFFFAOYSA-N;   SMILES=C1(=NCC=2N(C=3C1=CC(=CC3)Cl)C(=NC2)C)C=4C=CC=CC4F;   buccolam;   mezolam;   midazolamum
 xref: CAS:59467-70-8 "ChemIDplus";   CAS:59467-70-8 "KEGG COMPOUND";   CAS:59467-70-8 "NIST Chemistry WebBook";   DrugBank:DB00683;   Drug_Central:1802 "DrugCentral";   HMDB:HMDB0014821;   KEGG:C07524;   KEGG:D00550;   LINCS:LSM-5200
 xref_mesh: MESH:D008874
 xref: MetaCyc:CPD-20500;   PDBeChem:08J;   PMID:1832310 "Europe PMC";   PMID:26032507 "Europe PMC";   PMID:28706559 "Europe PMC";   PMID:29516686 "Europe PMC";   PMID:30076807 "Europe PMC";   PMID:30113394 "Europe PMC";   PMID:30157038 "Europe PMC";   Reaxys:625572 "Reaxys";   Wikipedia:Midazolam


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midazolam term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb11 ATP binding cassette subfamily B member 11 JBrowse link 3 55,480,024 55,587,946 RGD:6480464
G Abcb1a ATP binding cassette subfamily B member 1A JBrowse link 4 22,339,829 22,517,642 RGD:6480464
G Abcb6 ATP binding cassette subfamily B member 6 JBrowse link 9 82,373,950 82,382,228 RGD:6480464
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:6480464
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 JBrowse link 8 62,472,087 62,478,122 RGD:6480464
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 JBrowse link 6 2,308,179 2,316,739 RGD:6480464
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 JBrowse link 7 99,142,431 99,183,540 RGD:6480464
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 JBrowse link 1 147,236,480 147,307,988 RGD:6480464
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 JBrowse link 7 123,599,264 123,608,436 RGD:6480464
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 JBrowse link 1 213,511,892 213,522,195 RGD:6480464
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 JBrowse link 12 11,641,500 11,677,818 RGD:6480464
G Cyp3a23/3a1 cytochrome P450, family 3, subfamily a, polypeptide 23/polypeptide 1 JBrowse link 12 11,053,888 11,082,742 RGD:6480464
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 JBrowse link 12 19,074,288 19,114,491 RGD:6480464
G Gabra4 gamma-aminobutyric acid type A receptor alpha4 subunit JBrowse link 14 39,154,072 39,230,994 RGD:6480464
G Gabra6 gamma-aminobutyric acid type A receptor alpha 6 subunit JBrowse link 10 27,847,447 27,862,896 RGD:6480464
G Gabrb3 gamma-aminobutyric acid type A receptor beta 3 subunit JBrowse link 1 113,034,251 113,265,364 RGD:6480464
G Gabre gamma-aminobutyric acid type A receptor epsilon subunit JBrowse link X 152,220,180 152,237,347 RGD:6480464
G Gabrg2 gamma-aminobutyric acid type A receptor gamma 2 subunit JBrowse link 10 27,090,913 27,179,786 RGD:6480464
G Gast gastrin JBrowse link 10 88,245,532 88,248,485 RGD:6480464
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A JBrowse link 10 5,707,806 6,123,568 RGD:6480464
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 JBrowse link 11 65,022,100 65,058,546 RGD:6480464
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 JBrowse link 13 89,585,072 89,591,278 RGD:6480464
G Star steroidogenic acute regulatory protein JBrowse link 16 71,036,204 71,040,847 RGD:6480464
G Syn1 synapsin I JBrowse link X 1,321,315 1,379,202 RGD:6480464
G Trh thyrotropin releasing hormone JBrowse link 4 124,110,716 124,113,242 RGD:6480464
G Trhr thyrotropin releasing hormone receptor JBrowse link 7 83,113,641 83,153,520 RGD:6480464
G Tspo translocator protein JBrowse link 7 124,460,358 124,470,610 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19669
    role 19613
      biological role 19611
        biochemical role 19138
          apoptosis inducer 10783
            midazolam 27
              midazolam hydrochloride 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19669
    subatomic particle 19665
      composite particle 19665
        hadron 19665
          baryon 19665
            nucleon 19665
              atomic nucleus 19665
                atom 19665
                  main group element atom 19545
                    p-block element atom 19545
                      carbon group element atom 19428
                        carbon atom 19420
                          organic molecular entity 19420
                            organic molecule 19343
                              organic cyclic compound 19093
                                carbocyclic compound 17510
                                  benzenoid aromatic compound 17032
                                    benzenes 16747
                                      fluorobenzenes 1620
                                        monofluorobenzenes 1288
                                          midazolam 27
                                            midazolam hydrochloride 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.