cadmium sulfate - Ontology Report - Rat Genome Database

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CHEBI ONTOLOGY - ANNOTATIONS

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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:	cadmium sulfate	go back to main search page
Accession:	CHEBI:50292	browse the term
Definition:	A cadmium salt that has formula CdO4S.
Synonyms:	exact_synonym:	cadmium(2+) sulfate
	related_synonym:	Cadmiumsulfat; CdSO4; Formula=CdO4S; InChI=1S/Cd.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2; InChIKey=QCUOBSQYDGUHHT-UHFFFAOYSA-L; Kadmiumsulfat; SMILES=[Cd++].[O-]S([O-])(=O)=O; cadmium monosulfate; cadmium sulphate; sulfate de cadmium; sulfato de cadmio
	xref:	CAS:10124-36-4; Gmelin:8295
	xref_mesh:	MESH:C037123
	xref:	Wikipedia:Cadmium_sulfate

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Genes (275)

cadmium sulfate

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ATP binding cassette subfamily C member 4

increases expression

cadmium sulfate results in increased expression of ABCC4 mRNA

NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283

G

ABL proto-oncogene 2, non-receptor tyrosine kinase

increases expression

cadmium sulfate results in increased expression of ABL2 mRNA

PMID:12064557 PMID:14676411

NCBI chr13:68,673,702...68,770,846
Ensembl chr13:68,673,722...68,839,742

G

acetylcholinesterase

increases expression
multiple interactions

cadmium sulfate results in increased expression of ACHE mRNA; cadmium sulfate results in increased expression of ACHE protein
Curcumin inhibits the reaction [cadmium sulfate results in increased expression of ACHE mRNA]; Curcumin inhibits the reaction [cadmium sulfate results in increased expression of ACHE protein]

NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651

G

acyl-CoA synthetase family member 2

multiple interactions

cadmium sulfate affects the reaction [MTF1 affects the expression of ACSF2 mRNA]

NCBI chr10:79,504,510...79,546,714
Ensembl chr10:79,504,511...79,546,673

G

acyl-CoA synthetase long-chain family member 4

multiple interactions

[cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of ACSL4 mRNA

NCBI chr X:105,942,794...106,006,573
Ensembl chr X:105,942,799...106,006,427

G

activin A receptor type 2B

increases expression

cadmium sulfate results in increased expression of ACVR2B mRNA

NCBI chr 8:119,138,901...119,178,477
Ensembl chr 8:119,138,812...119,170,458

G

adenosine kinase

multiple interactions

[cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of ADK mRNA

NCBI chr15:2,863,241...3,246,453
Ensembl chr15:2,863,244...3,246,510

G

axin interactor, dorsalization associated

multiple interactions

cadmium sulfate affects the reaction [MTF1 affects the expression of AIDA mRNA]

NCBI chr13:94,940,311...94,967,920
Ensembl chr13:94,939,741...94,967,920

G

A-kinase anchoring protein 12

increases expression

cadmium sulfate results in increased expression of AKAP12 mRNA

NCBI chr 1:40,730,123...40,819,863
Ensembl chr 1:40,730,123...40,819,886

G

aldo-keto reductase family 1 member B10

multiple interactions

[cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of AKR1B10 mRNA

NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852

G

aldo-keto reductase family 1, member C1

multiple interactions

[cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of AKR1C1 mRNA

NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326

G

aldo-keto reductase family 1, member C2

multiple interactions

[cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of AKR1C2 mRNA

NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764

G

AMMECR1 like

decreases expression

cadmium sulfate results in decreased expression of AMMECR1L mRNA

NCBI chr18:23,386,114...23,411,177
Ensembl chr18:23,386,903...23,410,920

G

ankyrin repeat domain 1

increases expression

cadmium sulfate results in increased expression of ANKRD1 mRNA

PMID:12064557 PMID:14676411 PMID:21783983

NCBI chr 1:233,815,851...233,834,891
Ensembl chr 1:233,815,851...233,834,919

G

ankyrin repeat domain 40

decreases expression

cadmium sulfate results in decreased expression of ANKRD40 mRNA

NCBI chr10:79,282,075...79,295,322
Ensembl chr10:79,282,075...79,295,320

G

ankyrin repeat domain 46

decreases expression

cadmium sulfate results in decreased expression of ANKRD46 mRNA

NCBI chr 7:67,647,202...67,668,180
Ensembl chr 7:67,647,204...67,668,132

G

annexin A1

increases expression

cadmium sulfate results in increased expression of ANXA1 mRNA

PMID:12064557 PMID:14676411

NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343

G

aquaporin 8

increases expression

cadmium sulfate results in increased expression of AQP8 mRNA

NCBI chr 1:177,993,313...177,999,158
Ensembl chr 1:177,993,305...177,999,158

G

androgen receptor

multiple interactions

Androgens inhibits the reaction [cadmium sulfate inhibits the reaction [Androgens binds to AR protein]]; cadmium sulfate inhibits the reaction [Androgens binds to AR protein]; Dithiothreitol inhibits the reaction [cadmium sulfate inhibits the reaction [Androgens binds to AR protein]]

NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925

G

armadillo repeat containing, X-linked 2

multiple interactions

cadmium sulfate affects the reaction [MTF1 affects the expression of ARMCX2 mRNA]

NCBI chr X:97,980,662...97,985,523
Ensembl chr X:97,980,660...97,985,552

G

arrestin domain containing 3

multiple interactions

cadmium sulfate affects the reaction [MTF1 affects the expression of ARRDC3 mRNA]

NCBI chr 2:11,137,464...11,149,978
Ensembl chr 2:11,137,460...11,149,978

G

activating transcription factor 2

multiple interactions
increases phosphorylation

4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [cadmium sulfate results in increased phosphorylation of ATF2 protein]; diphenyleneiodonium inhibits the reaction [cadmium sulfate results in increased phosphorylation of ATF2 protein]

NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236

G

activating transcription factor 3

increases expression

cadmium sulfate results in increased expression of ATF3 mRNA

NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631

G

activating transcription factor 4

multiple interactions

[cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] affects the expression of ATF4 mRNA

NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446

G

ataxin 2

increases expression

cadmium sulfate results in increased expression of ATXN2 mRNA

PMID:14676411 PMID:21783983

NCBI chr12:34,754,132...34,851,175
Ensembl chr12:34,754,137...34,851,479

G

antizyme inhibitor 1

decreases expression

cadmium sulfate results in decreased expression of AZIN1 mRNA

NCBI chr 7:69,654,773...69,681,578
Ensembl chr 7:69,654,663...69,681,578

G

BAG cochaperone 3

increases expression

cadmium sulfate results in increased expression of BAG3 mRNA

NCBI chr 1:183,103,038...183,126,862
Ensembl chr 1:183,102,871...183,126,858

G

basic helix-loop-helix family, member e40

decreases expression
multiple interactions

cadmium sulfate results in decreased expression of BHLHE40 mRNA
[cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of BHLHE40 mRNA

PMID:18654764 PMID:21783983

NCBI chr 4:141,618,453...141,624,154
Ensembl chr 4:141,618,476...141,624,774

G

bactericidal/permeability-increasing protein

increases expression

cadmium sulfate results in increased expression of BPI mRNA

PMID:12064557 PMID:14676411

NCBI chr 3:146,909,626...146,936,487
Ensembl chr 3:146,909,629...146,936,221

G

calcyclin binding protein

increases expression

cadmium sulfate results in increased expression of CACYBP mRNA

PMID:12064557 PMID:14676411 PMID:21783983

NCBI chr13:72,437,485...72,447,810
Ensembl chr13:72,437,490...72,450,177

G

calbindin 1

increases expression

cadmium sulfate results in increased expression of CALB1 mRNA

NCBI chr 5:29,375,624...29,402,532
Ensembl chr 5:29,375,642...29,402,431

G

caspase 3

multiple interactions
increases activity

2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [cadmium sulfate results in increased activity of CASP3 protein]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [cadmium sulfate results in increased activity of CASP3 protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [cadmium sulfate results in increased activity of CASP3 protein]

NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648

G

caspase 7

multiple interactions
increases activity

2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [cadmium sulfate results in increased activity of CASP7 protein]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [cadmium sulfate results in increased activity of CASP7 protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [cadmium sulfate results in increased activity of CASP7 protein]

NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729

G

carbonyl reductase 3

increases expression

cadmium sulfate results in increased expression of CBR3 mRNA

NCBI chr11:33,008,615...33,016,877
Ensembl chr11:33,008,615...33,016,875

G

cellular communication network factor 1

decreases expression

cadmium sulfate results in decreased expression of CCN1 mRNA

NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484

G

cyclin A1

multiple interactions

[cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in decreased expression of CCNA1 mRNA

NCBI chr 2:139,231,738...139,278,066
Ensembl chr 2:139,201,074...139,243,157

G

cyclin G1

increases expression

cadmium sulfate results in increased expression of CCNG1 mRNA

NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641

G

cyclin-dependent kinase inhibitor 1A

increases expression

cadmium sulfate results in increased expression of CDKN1A mRNA

PMID:19274763 PMID:21783983

NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585

G

centrosomal protein 68

multiple interactions

cadmium sulfate affects the reaction [MTF1 affects the expression of CEP68 mRNA]

NCBI chr14:94,447,973...94,470,533
Ensembl chr14:94,449,055...94,470,517

G

coiled-coil-helix-coiled-coil-helix domain containing 7

decreases expression

cadmium sulfate results in decreased expression of CHCHD7 mRNA

NCBI chr 5:16,957,127...16,961,682
Ensembl chr 5:16,957,188...16,961,184

G

cold inducible RNA binding protein

increases expression

cadmium sulfate results in increased expression of CIRBP mRNA

NCBI chr 7:9,533,857...9,538,899
Ensembl chr 7:9,424,178...9,538,818

G

Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1

multiple interactions

cadmium sulfate inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of CITED1 mRNA]

NCBI chr X:67,350,376...67,355,072
Ensembl chr X:67,350,373...67,355,162

G

component of oligomeric golgi complex 8

decreases expression

cadmium sulfate results in decreased expression of COG8 mRNA

NCBI chr19:34,951,625...34,962,377
Ensembl chr19:34,951,627...34,962,397

G

coenzyme Q3 methyltransferase

decreases expression

cadmium sulfate results in decreased expression of COQ3 mRNA

NCBI chr 5:35,429,567...35,460,613
Ensembl chr 5:35,429,574...35,460,607

G

coactosin-like F-actin binding protein 1

multiple interactions

cadmium sulfate affects the reaction [MTF1 affects the expression of COTL1 mRNA]

NCBI chr19:47,871,689...47,906,010
Ensembl chr19:47,871,694...47,911,689

G

cAMP responsive element binding protein 1

multiple interactions
increases phosphorylation

[cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] affects the expression of CREB1 mRNA
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [cadmium sulfate results in increased phosphorylation of CREB1 protein]

PMID:14687664 PMID:18654764

NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816

G

cysteine and glycine-rich protein 1

multiple interactions
increases expression

cadmium sulfate affects the reaction [MTF1 affects the expression of CSRP1 mRNA]; MTF1 affects the reaction [cadmium sulfate results in increased expression of CSRP1 mRNA]

NCBI chr13:47,158,171...47,179,388
Ensembl chr13:47,167,789...47,179,384

G

cleavage stimulation factor subunit 3

increases expression

cadmium sulfate results in increased expression of CSTF3 mRNA

NCBI chr 3:90,966,415...91,037,669
Ensembl chr 3:90,966,354...91,042,196

G

cathepsin E

multiple interactions

cadmium sulfate affects the reaction [MTF1 affects the expression of CTSE mRNA]

NCBI chr13:43,091,954...43,114,509
Ensembl chr13:43,092,128...43,114,502

G

C-X-C motif chemokine ligand 2

increases expression

cadmium sulfate results in increased expression of CXCL2 mRNA; cadmium sulfate results in increased expression of CXCL2 protein

NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075

G

C-X-C motif chemokine ligand 3

increases expression

cadmium sulfate results in increased expression of CXCL1 mRNA; cadmium sulfate results in increased expression of CXCL1 protein

NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511

G

cytochrome b-561

multiple interactions

cadmium sulfate affects the reaction [MTF1 affects the expression of CYB561 mRNA]

NCBI chr10:90,878,052...90,888,734
Ensembl chr10:90,878,054...90,884,787

G

cytochrome P450, family 39, subfamily a, polypeptide 1

multiple interactions

cadmium sulfate affects the reaction [MTF1 affects the expression of CYP39A1 mRNA]

NCBI chr 9:17,230,455...17,306,775
Ensembl chr 9:17,230,455...17,306,775

G

deoxycytidine kinase

multiple interactions

cadmium sulfate affects the reaction [MTF1 affects the expression of DCK mRNA]

NCBI chr14:19,305,218...19,326,247
Ensembl chr14:19,305,218...19,326,247

G

dopa decarboxylase

increases expression

cadmium sulfate results in increased expression of DDC mRNA

NCBI chr14:86,378,685...86,469,189
Ensembl chr14:86,378,685...86,469,208

G

DNA-damage-inducible transcript 4-like

increases expression

cadmium sulfate results in increased expression of DDIT4L mRNA

NCBI chr 2:226,128,273...226,131,044
Ensembl chr 2:226,128,276...226,131,375

G

DEAD-box helicase 1

decreases expression

cadmium sulfate results in decreased expression of DDX1 mRNA

NCBI chr 6:35,996,469...36,027,340
Ensembl chr 6:35,996,469...36,027,365

G

DnaJ heat shock protein family (Hsp40) member B1

increases expression

cadmium sulfate results in increased expression of DNAJB1 mRNA

NCBI chr19:24,522,731...24,526,419
Ensembl chr19:24,522,717...24,526,458

G

deoxyhypusine hydroxylase

increases expression

cadmium sulfate results in increased expression of DOHH mRNA

NCBI chr 7:8,321,466...8,326,305
Ensembl chr 7:8,321,466...8,326,289

G

early endosome antigen 1

multiple interactions

[cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of EEA1 mRNA

NCBI chr 7:30,554,686...30,722,186
Ensembl chr 7:30,554,552...30,718,487

G

eukaryotic translation initiation factor 2, subunit 3, structural gene Y-linked

decreases expression

cadmium sulfate results in decreased expression of EIF2S3Y mRNA

NCBI chr Y:869,654...889,341
Ensembl chr Y:869,689...889,340

G

eukaryotic translation initiation factor 4A2

decreases expression

cadmium sulfate results in decreased expression of EIF4A2 mRNA

NCBI chr11:77,764,126...77,770,810
Ensembl chr11:77,764,124...77,770,781

G

ETS transcription factor ELK1

multiple interactions

[cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] affects the expression of ELK1 mRNA

NCBI chr X:1,138,826...1,155,713
Ensembl chr X:1,139,756...1,155,713

G

ectonucleoside triphosphate diphosphohydrolase 5

increases expression

cadmium sulfate results in increased expression of ENTPD5 mRNA

NCBI chr 6:104,019,095...104,055,311
Ensembl chr 6:104,019,185...104,055,530

G

epiphycan

decreases expression

cadmium sulfate results in decreased expression of EPYC mRNA

NCBI chr 7:32,436,620...32,474,326
Ensembl chr 7:32,436,620...32,474,135

G

ergosterol biosynthesis 28 homolog

multiple interactions

[cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of ERG28 mRNA

NCBI chr 6:105,474,112...105,483,078
Ensembl chr 6:105,474,113...105,483,078

G

ETS variant transcription factor 1

increases expression

cadmium sulfate results in increased expression of ETV1 mRNA

NCBI chr 6:55,590,149...55,681,784
Ensembl chr 6:55,590,234...55,681,775

G

exocyst complex component 5

multiple interactions

[cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of EXOC5 mRNA

NCBI chr15:22,310,682...22,355,695
Ensembl chr15:22,308,946...22,355,335

G

coagulation factor II (thrombin) receptor

multiple interactions

[cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of F2R mRNA

NCBI chr 2:26,869,343...26,885,856
Ensembl chr 2:26,868,404...26,885,870

G

family with sequence similarity 181, member B

multiple interactions

cadmium sulfate affects the reaction [MTF1 affects the expression of FAM181B mRNA]

NCBI chr 1:147,166,428...147,167,925
Ensembl chr 1:147,124,740...147,168,298
Ensembl chr 1:147,124,740...147,168,298

G

Fc gamma receptor 1A

multiple interactions

cadmium sulfate affects the reaction [MTF1 affects the expression of FCGR1 mRNA]

NCBI chr 2:183,851,075...183,860,077
Ensembl chr 2:183,851,077...183,859,994

G

fem-1 homolog B

decreases expression

cadmium sulfate results in decreased expression of FEM1B mRNA

NCBI chr 8:63,265,301...63,278,577
Ensembl chr 8:63,265,301...63,278,577

G

fibrinogen-like 2

multiple interactions

cadmium sulfate affects the reaction [MTF1 affects the expression of FGL2 mRNA]

NCBI chr 4:13,710,566...13,716,207
Ensembl chr 4:13,710,575...13,716,207

G

FKBP prolyl isomerase 4

increases expression

cadmium sulfate results in increased expression of FKBP4 mRNA

NCBI chr 4:161,703,379...161,711,833
Ensembl chr 4:161,703,379...161,711,833

G

formin 2

multiple interactions

cadmium sulfate affects the reaction [MTF1 affects the expression of FMN2 mRNA]

NCBI chr13:86,454,256...86,771,437
Ensembl chr13:86,453,926...86,771,411

G

Fos proto-oncogene, AP-1 transcription factor subunit

increases expression

cadmium sulfate results in increased expression of FOS mRNA

PMID:10362023 PMID:21783983

NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036

G

ferritin heavy chain 1

increases expression

cadmium sulfate results in increased expression of FTH1 mRNA

PMID:12064557 PMID:14676411

NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424

G

ferritin light chain 1

increases expression

cadmium sulfate results in increased expression of FTL mRNA

PMID:12064557 PMID:14676411 PMID:21783983

NCBI chr 1:95,936,387...95,938,234
Ensembl chr 1:95,936,387...95,939,725
Ensembl chr10:95,936,387...95,939,725

G

glucose-6-phosphatase catalytic subunit 1

decreases expression

cadmium sulfate results in decreased expression of G6PC1 mRNA

NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804

G

growth arrest and DNA-damage-inducible, alpha

multiple interactions

cadmium sulfate affects the reaction [MTF1 affects the expression of GADD45A mRNA]

NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115

G

growth arrest-specific 1

multiple interactions

[cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in decreased expression of GAS1 mRNA

NCBI chr17:4,482,168...4,485,153

G

1,4-alpha-glucan branching enzyme 1

increases expression

cadmium sulfate results in increased expression of GBE1 mRNA

PMID:12064557 PMID:14676411

NCBI chr11:8,734,806...9,000,226
Ensembl chr11:8,734,820...9,000,210

G

glutamate-cysteine ligase, catalytic subunit

multiple interactions
increases expression

[cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of GCLC mRNA
cadmium sulfate results in increased expression of GCLC mRNA

PMID:12064557 PMID:16221973 PMID:18654764

NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544

G

gap junction protein, beta 2

decreases expression

cadmium sulfate results in decreased expression of GJB2 mRNA

NCBI chr15:31,260,390...31,278,222
Ensembl chr15:31,260,357...31,278,177

G

G kinase anchoring protein 1

decreases expression

cadmium sulfate results in decreased expression of GKAP1 mRNA

NCBI chr17:6,383,963...6,423,684
Ensembl chr17:6,383,963...6,423,679

G

ganglioside GM2 activator

multiple interactions

[cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of GM2A mRNA

NCBI chr10:39,219,221...39,231,756
Ensembl chr10:39,219,243...39,231,757

G

G protein subunit alpha 13

multiple interactions

[cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of GNA13 mRNA

NCBI chr10:94,337,939...94,370,774
Ensembl chr10:94,337,725...94,370,774

G

glypican 3

multiple interactions

cadmium sulfate inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of GPC3 mRNA]

NCBI chr X:131,868,986...132,236,824
Ensembl chr X:131,868,990...132,236,798

G

glycoprotein nmb

multiple interactions

[cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of GPNMB mRNA

NCBI chr 4:78,010,247...78,031,491
Ensembl chr 4:78,010,197...78,049,367

G

G protein-coupled receptor, class C, group 5, member A

increases expression

cadmium sulfate results in increased expression of GPRC5A mRNA

PMID:12064557 PMID:14676411

NCBI chr 4:167,903,542...167,922,276
Ensembl chr 4:167,903,542...167,922,260

G

glutathione peroxidase 2

multiple interactions

[cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of GPX2 mRNA

NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877

G

G protein-coupled receptor kinase 5

increases expression

cadmium sulfate results in increased expression of GRK5 mRNA

NCBI chr 1:260,028,269...260,223,699
Ensembl chr 1:260,028,242...260,218,701

G

glutathione-disulfide reductase

increases expression

cadmium sulfate results in increased expression of GSR mRNA

NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661

G

glutathione S-transferase mu 4

increases expression

cadmium sulfate results in increased expression of GSTM4 mRNA

NCBI chr 2:195,667,940...195,685,315
Ensembl chr 2:195,680,004...195,685,323

G

glutathione S-transferase omega 1

multiple interactions

cadmium sulfate affects the reaction [MTF1 affects the expression of GSTO1 mRNA]

NCBI chr 1:246,721,089...246,731,228
Ensembl chr 1:246,721,221...246,731,468

G

granzyme A

multiple interactions

cadmium sulfate affects the reaction [MTF1 affects the expression of GZMA mRNA]

NCBI chr 2:44,740,569...44,752,502
Ensembl chr 2:44,740,569...44,752,493

G

granzyme B

multiple interactions

cadmium sulfate affects the reaction [MTF1 affects the expression of GZMB mRNA]

NCBI chr15:30,343,352...30,346,814
Ensembl chr15:30,173,603...30,346,814

G

H2A.Z variant histone 2

multiple interactions

cadmium sulfate affects the reaction [MTF1 affects the expression of H2AZ2 mRNA]

NCBI chr14:81,293,304...81,312,209
Ensembl chr14:81,293,299...81,312,144

G

heart and neural crest derivatives expressed 2

multiple interactions

cadmium sulfate inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of HAND2 mRNA]

NCBI chr16:32,917,448...32,920,791
Ensembl chr16:32,917,823...32,919,891

G

heart development protein with EGF-like domains 1

multiple interactions

[cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of HEG1 mRNA

NCBI chr11:67,006,954...67,095,020
Ensembl chr11:66,957,190...67,095,051

G

homocysteine inducible ER protein with ubiquitin like domain 1

decreases expression
increases expression

cadmium sulfate results in decreased expression of HERPUD1 mRNA
cadmium sulfate results in increased expression of HERPUD1 mRNA

PMID:12064557 PMID:14676411 PMID:21783983

NCBI chr19:10,598,411...10,609,002
Ensembl chr19:10,598,417...10,618,424

G

HIC ZBTB transcriptional repressor 1

multiple interactions

[cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] affects the expression of HIC1 mRNA

NCBI chr10:60,014,520...60,019,475
Ensembl chr10:60,011,528...60,019,475

G

huntingtin interacting protein 1 related

multiple interactions

cadmium sulfate affects the reaction [MTF1 affects the expression of HIP1R mRNA]

NCBI chr12:32,590,164...32,618,841
Ensembl chr12:32,590,165...32,618,734

G

high mobility group AT-hook 2

decreases expression

cadmium sulfate results in decreased expression of HMGA2 mRNA

NCBI chr 7:55,877,145...55,998,813
Ensembl chr 7:55,880,112...55,994,784

G

3-hydroxy-3-methylglutaryl-CoA reductase

multiple interactions

[cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of HMGCR mRNA

NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703

G

3-hydroxy-3-methylglutaryl-CoA synthase 1

multiple interactions

[cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of HMGCS1 mRNA

NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100

G

heme oxygenase 1

multiple interactions
increases expression

cadmium sulfate promotes the reaction [HSF1 protein binds to HMOX1 promoter]
cadmium sulfate results in increased expression of HMOX1 mRNA
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [cadmium sulfate results in increased expression of HMOX1 protein]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [cadmium sulfate results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [cadmium sulfate results in increased expression of HMOX1 protein]

PMID:14687664 PMID:17244614 PMID:21783983

NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079

G

heterogeneous nuclear ribonucleoprotein A1

decreases expression

cadmium sulfate results in decreased expression of HNRNPA1 protein

NCBI chr 7:134,375,318...134,381,610
Ensembl chr 7:134,375,150...134,381,609

G

heterogeneous nuclear ribonucleoprotein D

multiple interactions

[cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in decreased expression of HNRNPD mRNA

NCBI chr14:9,615,375...9,638,975
Ensembl chr14:9,615,479...9,633,786

G

heat shock transcription factor 1

multiple interactions
increases activity

cadmium sulfate promotes the reaction [HSF1 protein binds to HMOX1 promoter]; cadmium sulfate promotes the reaction [HSF1 protein binds to HSPA1A enhancer]; cadmium sulfate promotes the reaction [HSF1 protein binds to HSPA1A promoter]
cadmium sulfate results in increased activity of HSF1 protein

PMID:16460681 PMID:17244614

NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011

G

heat shock protein 90 alpha family class A member 1

increases expression

cadmium sulfate results in increased expression of HSP90AA1 protein

NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268

G

heat shock protein 90 alpha family class B member 1

increases expression

cadmium sulfate results in increased expression of HSP90AB1 mRNA

PMID:12064557 PMID:21783983

NCBI chr 9:15,432,986...15,438,358
Ensembl chr 9:15,433,691...15,438,488

G

heat shock protein family A (Hsp70) member 14

increases expression

cadmium sulfate results in increased expression of HSPA14 mRNA

NCBI chr17:74,728,945...74,749,727
Ensembl chr17:74,728,899...74,749,727

G

heat shock protein family A (Hsp70) member 1A

multiple interactions
increases expression

cadmium sulfate promotes the reaction [HSF1 protein binds to HSPA1A enhancer]; cadmium sulfate promotes the reaction [HSF1 protein binds to HSPA1A promoter]
cadmium sulfate results in increased expression of HSPA1A mRNA

PMID:16460681 PMID:17244614 PMID:21783983

NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227

G

heat shock protein family A (Hsp70) member 5

increases expression

cadmium sulfate results in increased expression of HSPA5 mRNA

NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891

G

heat shock protein family A (Hsp70) member 6 like, pseudogene 1

increases expression

cadmium sulfate results in increased expression of HSPA6 mRNA

NCBI chr13:83,273,176...83,274,317

G

heat shock protein family A (Hsp70) member 8

increases expression

cadmium sulfate results in increased expression of HSPA8 mRNA

NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259

G

heat shock protein family H (Hsp110) member 1

increases expression

cadmium sulfate results in increased expression of HSPH1 mRNA

NCBI chr12:5,390,916...5,410,224
Ensembl chr12:5,390,922...5,410,224

G

HIV-1 Tat interactive protein 2

increases expression

cadmium sulfate results in increased expression of HTATIP2 mRNA

NCBI chr 1:99,473,411...99,488,632
Ensembl chr 1:99,469,245...99,488,629

G

HUS1 checkpoint clamp component

decreases expression

cadmium sulfate results in decreased expression of HUS1 mRNA

NCBI chr14:83,688,702...83,703,466
Ensembl chr14:83,688,708...83,703,442

G

inhibitor of DNA binding 1

decreases expression

cadmium sulfate results in decreased expression of ID1 mRNA

NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419

G

inhibitor of DNA binding 3

multiple interactions

cadmium sulfate affects the reaction [MTF1 affects the expression of ID3 mRNA]

NCBI chr 5:148,372,784...148,374,353
Ensembl chr 5:148,372,762...148,374,349

G

immediate early response 3

multiple interactions

cadmium sulfate affects the reaction [MTF1 affects the expression of IER3 mRNA]

NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583

G

intraflagellar transport 140

multiple interactions

cadmium sulfate affects the reaction [MTF1 affects the expression of IFT140 mRNA]

NCBI chr10:14,032,665...14,121,682
Ensembl chr10:14,032,648...14,120,433

G

inhibitor of nuclear factor kappa B kinase regulatory subunit gamma

increases expression

cadmium sulfate results in increased expression of IKBKG mRNA

NCBI chr X:152,216,485...152,241,476
Ensembl chr X:152,216,596...152,239,499

G

interleukin 13 receptor subunit alpha 2

multiple interactions

[cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in decreased expression of IL13RA2 mRNA

NCBI chr X:111,002,590...111,074,053
Ensembl chr X:111,002,592...111,072,381

G

interleukin 1 alpha

increases expression

cadmium sulfate results in increased expression of IL1A mRNA

PMID:12064557 PMID:14676411

NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822

G

interleukin 33

multiple interactions

cadmium sulfate affects the reaction [MTF1 affects the expression of IL33 mRNA]

NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373

G

interleukin 6

multiple interactions
increases expression
increases secretion

3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [cadmium sulfate results in increased secretion of IL6 protein]; Curcumin inhibits the reaction [cadmium sulfate results in increased expression of IL6 mRNA]; Curcumin inhibits the reaction [cadmium sulfate results in increased secretion of IL6 protein]

PMID:22094458 PMID:22142850

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

G

interleukin 7

multiple interactions

cadmium sulfate affects the reaction [MTF1 affects the expression of IL7 mRNA]

NCBI chr 2:94,235,219...94,280,075
Ensembl chr 2:94,234,766...94,280,075

G

interleukin 7 receptor

increases expression

cadmium sulfate results in increased expression of IL7R mRNA

NCBI chr 2:58,452,393...58,477,757
Ensembl chr 2:58,454,217...58,477,757

G

inner membrane mitochondrial protein

decreases expression

cadmium sulfate results in decreased expression of IMMT mRNA

NCBI chr 4:103,880,482...103,919,116
Ensembl chr 4:103,880,459...103,919,109

G

insulin induced gene 1

multiple interactions

[cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of INSIG1 mRNA

NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952

G

integrator complex subunit 8

decreases expression

cadmium sulfate results in decreased expression of INTS8 mRNA

NCBI chr 5:24,295,542...24,344,642
Ensembl chr 5:24,297,191...24,344,740

G

Jun proto-oncogene, AP-1 transcription factor subunit

increases phosphorylation
increases expression
multiple interactions

cadmium sulfate results in increased phosphorylation of JUN protein
cadmium sulfate results in increased expression of JUN mRNA
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [cadmium sulfate results in increased phosphorylation of JUN protein]; diphenyleneiodonium inhibits the reaction [cadmium sulfate results in increased phosphorylation of JUN protein]; losoxantrone inhibits the reaction [cadmium sulfate results in increased phosphorylation of JUN protein]

PMID:14687664 PMID:21783983 PMID:22094458

NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656

G

potassium voltage-gated channel, modifier subfamily S, member 3

multiple interactions

[cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of KCNS3 mRNA

NCBI chr 6:33,808,314...33,865,018
Ensembl chr 6:33,808,216...33,865,125

G

KDEL endoplasmic reticulum protein retention receptor 2

increases expression

cadmium sulfate results in increased expression of KDELR2 mRNA

NCBI chr12:11,138,820...11,157,117
Ensembl chr12:11,138,820...11,157,153

G

kelch-like family member 24

multiple interactions

[cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of KLHL24 mRNA

NCBI chr11:80,843,621...80,877,649
Ensembl chr11:80,846,755...80,877,636

G

kelch-like family member 7

multiple interactions

[cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of KLHL7 mRNA

NCBI chr 4:11,006,366...11,055,399
Ensembl chr 4:11,006,375...11,055,541

G

killer cell lectin like receptor K1

decreases expression

cadmium sulfate results in decreased expression of KLRK1 mRNA

PMID:12064557 PMID:14676411

NCBI chr 4:163,079,887...163,092,434
Ensembl chr 4:163,081,927...163,092,459

G

karyopherin subunit alpha 1

decreases expression

cadmium sulfate results in decreased expression of KPNA1 mRNA

NCBI chr11:64,715,844...64,774,647
Ensembl chr11:64,717,563...64,774,623

G

keratin 14

increases expression

cadmium sulfate results in increased expression of KRT14 mRNA

NCBI chr10:85,137,786...85,142,054
Ensembl chr10:85,066,802...85,171,799

G

keratin 17

increases expression

cadmium sulfate results in increased expression of KRT17 mRNA

PMID:12064557 PMID:14676411 PMID:21783983

NCBI chr10:85,178,673...85,183,392
Ensembl chr10:85,178,675...85,183,392

G

lysosomal-associated membrane protein 3

multiple interactions

[cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in decreased expression of LAMP3 mRNA

NCBI chr11:81,153,491...81,224,643
Ensembl chr11:81,193,649...81,221,784

G

lipoprotein lipase

multiple interactions

cadmium sulfate affects the reaction [MTF1 affects the expression of LPL mRNA]

NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249

G

ligand dependent nuclear receptor interacting factor 1

increases expression

cadmium sulfate results in increased expression of LRIF1 mRNA

NCBI chr 2:194,231,397...194,322,489
Ensembl chr 2:194,230,951...194,322,483

G

MAF bZIP transcription factor G

increases expression

cadmium sulfate results in increased expression of MAFG mRNA

PMID:12064557 PMID:21783983

NCBI chr10:105,903,307...105,911,808
Ensembl chr10:105,903,237...105,912,026

G

mitogen activated protein kinase 1

multiple interactions
increases phosphorylation

cadmium sulfate results in increased phosphorylation of and results in increased activity of MAPK1 protein
cadmium sulfate results in increased phosphorylation of and results in increased activity of MAPK1 protein; Curcumin inhibits the reaction [cadmium sulfate results in increased phosphorylation of and results in increased activity of MAPK1 protein]; diphenyleneiodonium inhibits the reaction [cadmium sulfate results in increased phosphorylation of and results in increased activity of MAPK1 protein]; MAPK1 mutant form inhibits the reaction [cadmium sulfate results in increased secretion of CXCL8 protein]; U 0126 inhibits the reaction [cadmium sulfate results in increased phosphorylation of and results in increased activity of MAPK1 protein]
cadmium sulfate results in increased phosphorylation of MAPK1 protein
Acetylcysteine inhibits the reaction [cadmium sulfate results in increased phosphorylation of MAPK1 protein]; cadmium sulfate inhibits the reaction [[Norepinephrine co-treated with Propranolol] results in increased phosphorylation of MAPK1 protein]; Glutathione inhibits the reaction [cadmium sulfate results in increased phosphorylation of MAPK1 protein]

PMID:11880281 PMID:20600713 PMID:22094458 PMID:22142850 PMID:22767315

NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616

G

mitogen activated protein kinase 3

multiple interactions
increases phosphorylation

cadmium sulfate results in increased phosphorylation of and results in increased activity of MAPK3 protein
cadmium sulfate results in increased phosphorylation of and results in increased activity of MAPK3 protein; Curcumin inhibits the reaction [cadmium sulfate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; diphenyleneiodonium inhibits the reaction [cadmium sulfate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; MAPK3 mutant form inhibits the reaction [cadmium sulfate results in increased secretion of CXCL8 protein]; U 0126 inhibits the reaction [cadmium sulfate results in increased phosphorylation of and results in increased activity of MAPK3 protein]
cadmium sulfate results in increased phosphorylation of MAPK3 protein
Acetylcysteine inhibits the reaction [cadmium sulfate results in increased phosphorylation of MAPK3 protein]; cadmium sulfate inhibits the reaction [[Norepinephrine co-treated with Propranolol] results in increased phosphorylation of MAPK3 protein]; Glutathione inhibits the reaction [cadmium sulfate results in increased phosphorylation of MAPK3 protein]

PMID:11880281 PMID:20600713 PMID:22094458 PMID:22142850 PMID:22767315

NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863

G

mitogen-activated protein kinase 8

multiple interactions
increases phosphorylation

Acetylcysteine inhibits the reaction [cadmium sulfate results in increased phosphorylation of and results in increased activity of MAPK8 protein]; cadmium sulfate results in increased phosphorylation of and results in increased activity of MAPK8 protein
cadmium sulfate results in increased phosphorylation of MAPK8 protein
Acetylcysteine inhibits the reaction [cadmium sulfate results in increased phosphorylation of MAPK8 protein]; Glutathione inhibits the reaction [cadmium sulfate results in increased phosphorylation of MAPK8 protein]

PMID:14687664 PMID:22767315

NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981

G

mitogen-activated protein kinase 9

multiple interactions
increases phosphorylation

Acetylcysteine inhibits the reaction [cadmium sulfate results in increased phosphorylation of and results in increased activity of MAPK9 protein]; cadmium sulfate results in increased phosphorylation of and results in increased activity of MAPK9 protein
Acetylcysteine inhibits the reaction [cadmium sulfate results in increased phosphorylation of MAPK9 protein]; Glutathione inhibits the reaction [cadmium sulfate results in increased phosphorylation of MAPK9 protein]

PMID:14687664 PMID:22767315

NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178

G

methionine adenosyltransferase 2A

decreases expression

cadmium sulfate results in decreased expression of MAT2A mRNA

PMID:12064557 PMID:14676411 PMID:21783983

NCBI chr 4:104,489,877...104,495,447
Ensembl chr 4:104,488,466...104,495,493

G

melanoma cell adhesion molecule

increases expression

cadmium sulfate results in increased expression of MCAM mRNA

NCBI chr 8:44,479,391...44,487,575
Ensembl chr 8:44,479,376...44,487,571

G

minichromosome maintenance complex component 2

multiple interactions

cadmium sulfate affects the reaction [MTF1 affects the expression of MCM2 mRNA]

NCBI chr 4:121,346,434...121,360,962
Ensembl chr 4:121,346,434...121,360,847

G

minichromosome maintenance complex component 5

multiple interactions

cadmium sulfate affects the reaction [MTF1 affects the expression of MCM5 mRNA]

NCBI chr19:13,483,030...13,504,389
Ensembl chr19:13,483,066...13,504,389

G

malic enzyme 1

increases expression

cadmium sulfate results in increased expression of ME1 mRNA

NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304

G

MLLT3, super elongation complex subunit

decreases expression

cadmium sulfate results in decreased expression of MLLT3 mRNA

NCBI chr 5:102,259,075...102,515,447
Ensembl chr 5:102,260,011...102,515,361

G

molybdenum cofactor sulfurase

increases expression

cadmium sulfate results in increased expression of MOCOS mRNA

NCBI chr18:15,931,659...15,977,415
Ensembl chr18:15,931,654...15,977,187

G

MAGUK p55 scaffold protein 7

multiple interactions

cadmium sulfate affects the reaction [MTF1 affects the expression of MPP7 mRNA]

NCBI chr17:55,439,939...55,706,810
Ensembl chr17:55,442,696...55,706,748

G

mitochondrial ribosomal protein S2

decreases expression

cadmium sulfate results in decreased expression of MRPS2 mRNA

NCBI chr 3:11,803,044...11,806,341
Ensembl chr 3:11,801,310...11,806,313

G

msh homeobox 2

multiple interactions

cadmium sulfate inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of MSX2 mRNA]

NCBI chr17:11,097,214...11,102,879
Ensembl chr17:11,097,103...11,102,879

G

metallothionein 1

affects expression
decreases expression
increases expression
multiple interactions

cadmium sulfate affects the expression of MT1A mRNA
cadmium sulfate results in decreased expression of MT1A protein
cadmium sulfate results in increased expression of MT1 gene
cadmium sulfate affects the reaction [MTF1 affects the expression of MT1 mRNA]

PMID:2412205 PMID:16221973 PMID:30051583

NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049
Ensembl chr17:10,826,032...10,827,049

G

metallothionein 1, pseudogene 3

increases expression

cadmium sulfate results in increased expression of MT1E mRNA

PMID:12064557 PMID:14676411 PMID:21783983

NCBI chr17:74,786,652...74,787,040
Ensembl chr17:74,786,654...74,787,135

G

metallothionein 2A

multiple interactions
decreases expression
increases expression

cadmium sulfate affects the reaction [MTF1 affects the expression of MT2 mRNA]
cadmium sulfate results in decreased expression of MT2 mRNA
cadmium sulfate results in increased expression of MT2A mRNA

PMID:9325024 PMID:10362023 PMID:16221973 PMID:19274763 PMID:21783983

NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784

G

metallothionein 3

increases expression

cadmium sulfate results in increased expression of MT3 mRNA

PMID:12064557 PMID:14676411

NCBI chr19:10,848,754...10,850,158
Ensembl chr19:10,848,755...10,850,158

G

metal-regulatory transcription factor 1

multiple interactions
decreases response to substance

cadmium sulfate affects the reaction [MTF1 affects the expression of ACSF2 mRNA]; cadmium sulfate affects the reaction [MTF1 affects the expression of AIDA mRNA]; cadmium sulfate affects the reaction [MTF1 affects the expression of ARMCX2 mRNA]; cadmium sulfate affects the reaction [MTF1 affects the expression of ARRDC3 mRNA]; cadmium sulfate affects the reaction [MTF1 affects the expression of CEP68 mRNA]; cadmium sulfate affects the reaction [MTF1 affects the expression of COTL1 mRNA]; cadmium sulfate affects the reaction [MTF1 affects the expression of CSRP1 mRNA]; cadmium sulfate affects the reaction [MTF1 affects the expression of CTSE mRNA]; cadmium sulfate affects the reaction [MTF1 affects the expression of CYB561 mRNA]; cadmium sulfate affects the reaction [MTF1 affects the expression of CYP2B9 mRNA]; cadmium sulfate affects the reaction [MTF1 affects the expression of CYP39A1 mRNA]; cadmium sulfate affects the reaction [MTF1 affects the expression of DCK mRNA]; cadmium sulfate affects the reaction [MTF1 affects the expression of FAM181B mRNA]; cadmium sulfate affects the reaction [MTF1 affects the expression of FCGR1 mRNA]; cadmium sulfate affects the reaction [MTF1 affects the expression of FGL2 mRNA]; cadmium sulfate affects the reaction [MTF1 affects the expression of FMN2 mRNA]; cadmium sulfate affects the reaction [MTF1 affects the expression of GADD45A mRNA]; cadmium sulfate affects the reaction [MTF1 affects the expression of GSTO1 mRNA]; cadmium sulfate affects the reaction [MTF1 affects the expression of GZMA mRNA]; cadmium sulfate affects the reaction [MTF1 affects the expression of GZMB mRNA]; cadmium sulfate affects the reaction [MTF1 affects the expression of H2AZ2 mRNA]; cadmium sulfate affects the reaction [MTF1 affects the expression of HIP1R mRNA]; cadmium sulfate affects the reaction [MTF1 affects the expression of ID3 mRNA]; cadmium sulfate affects the reaction [MTF1 affects the expression of IER3 mRNA]; cadmium sulfate affects the reaction [MTF1 affects the expression of IFT140 mRNA]; cadmium sulfate affects the reaction [MTF1 affects the expression of IL33 mRNA]; cadmium sulfate affects the reaction [MTF1 affects the expression of IL7 mRNA]; cadmium sulfate affects the reaction [MTF1 affects the expression of LPL mRNA]; cadmium sulfate affects the reaction [MTF1 affects the expression of MCM2 mRNA]; cadmium sulfate affects the reaction [MTF1 affects the expression of MCM5 mRNA]; cadmium sulfate affects the reaction [MTF1 affects the expression of MPP7 mRNA]; cadmium sulfate affects the reaction [MTF1 affects the expression of MT1 mRNA]; cadmium sulfate affects the reaction [MTF1 affects the expression of MT2 mRNA]; cadmium sulfate affects the reaction [MTF1 affects the expression of MTF1 mRNA]; cadmium sulfate affects the reaction [MTF1 affects the expression of MYOM2 mRNA]; cadmium sulfate affects the reaction [MTF1 affects the expression of NCALD mRNA]; cadmium sulfate affects the reaction [MTF1 affects the expression of NCF4 mRNA]; cadmium sulfate affects the reaction [MTF1 affects the expression of NDRG1 mRNA]; cadmium sulfate affects the reaction [MTF1 affects the expression of PAQR7 mRNA]; cadmium sulfate affects the reaction [MTF1 affects the expression of PAXIP1 mRNA]; cadmium sulfate affects the reaction [MTF1 affects the expression of PDGFA mRNA]; cadmium sulfate affects the reaction [MTF1 affects the expression of PDXK mRNA]; cadmium sulfate affects the reaction [MTF1 affects the expression of PKM mRNA]; cadmium sulfate affects the reaction [MTF1 affects the expression of PLA2G4A mRNA]; cadmium sulfate affects the reaction [MTF1 affects the expression of PLK3 mRNA]; cadmium sulfate affects the reaction [MTF1 affects the expression of PLPP3 mRNA]; cadmium sulfate affects the reaction [MTF1 affects the expression of PPARG mRNA]; cadmium sulfate affects the reaction [MTF1 affects the expression of PRKAA2 mRNA]; cadmium sulfate affects the reaction [MTF1 affects the expression of PRSS23 mRNA]; cadmium sulfate affects the reaction [MTF1 affects the expression of RAB29 mRNA]; cadmium sulfate affects the reaction [MTF1 affects the expression of RAP2B mRNA]; cadmium sulfate affects the reaction [MTF1 affects the expression of RXRG mRNA]; cadmium sulfate affects the reaction [MTF1 affects the expression of SELENOW mRNA]; cadmium sulfate affects the reaction [MTF1 affects the expression of SERPINH1 mRNA]; cadmium sulfate affects the reaction [MTF1 affects the expression of SGPP2 mRNA]; cadmium sulfate affects the reaction [MTF1 affects the expression of SLC25A25 mRNA]; cadmium sulfate affects the reaction [MTF1 affects the expression of SLC39A10 mRNA]; cadmium sulfate affects the reaction [MTF1 affects the expression of SMAD7 mRNA]; cadmium sulfate affects the reaction [MTF1 affects the expression of SULT5A1 mRNA]; cadmium sulfate affects the reaction [MTF1 affects the expression of TIMP1 mRNA]; cadmium sulfate affects the reaction [MTF1 affects the expression of TMEM42 mRNA]; cadmium sulfate affects the reaction [MTF1 affects the expression of TTC4 mRNA]; cadmium sulfate affects the reaction [MTF1 affects the expression of UBC mRNA]; cadmium sulfate affects the reaction [MTF1 affects the expression of UBE3A mRNA]; cadmium sulfate affects the reaction [MTF1 affects the expression of UPP2 mRNA]; cadmium sulfate affects the reaction [MTF1 affects the expression of USP24 mRNA]; cadmium sulfate affects the reaction [MTF1 affects the expression of ZFP617 mRNA]; cadmium sulfate affects the reaction [MTF1 affects the expression of ZKSCAN6 mRNA]; MTF1 affects the reaction [cadmium sulfate results in increased expression of CSRP1 mRNA]; MTF1 affects the reaction [cadmium sulfate results in increased expression of NDRG1 mRNA]; MTF1 results in decreased susceptibility to [Buthionine Sulfoximine co-treated with cadmium sulfate]
MTF1 results in decreased susceptibility to cadmium sulfate

NCBI chr 5:137,062,319...137,107,136
Ensembl chr 5:137,062,376...137,107,136

G

max dimerization protein 1

increases expression

cadmium sulfate results in increased expression of MXD1 mRNA

NCBI chr 4:119,097,353...119,118,080
Ensembl chr 4:119,097,353...119,117,751

G

MYC proto-oncogene, bHLH transcription factor

decreases expression

cadmium sulfate results in decreased expression of MYC mRNA

NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630

G

myomesin 2

multiple interactions

cadmium sulfate affects the reaction [MTF1 affects the expression of MYOM2 mRNA]

NCBI chr16:74,520,148...74,592,658
Ensembl chr16:74,520,157...74,592,772

G

neurocalcin delta

multiple interactions

cadmium sulfate affects the reaction [MTF1 affects the expression of NCALD mRNA]

NCBI chr 7:68,532,671...68,964,740
Ensembl chr 7:68,534,421...68,964,496

G

neutrophil cytosolic factor 4

multiple interactions

cadmium sulfate affects the reaction [MTF1 affects the expression of NCF4 mRNA]

NCBI chr 7:109,825,420...109,843,389
Ensembl chr 7:109,826,020...109,843,389

G

N-myc downstream regulated 1

multiple interactions
increases expression

cadmium sulfate affects the reaction [MTF1 affects the expression of NDRG1 mRNA]; MTF1 affects the reaction [cadmium sulfate results in increased expression of NDRG1 mRNA]

PMID:12064557 PMID:14676411 PMID:16221973

NCBI chr 7:98,684,487...98,725,869
Ensembl chr 7:98,684,487...98,725,880

G

NADH:ubiquinone oxidoreductase complex assembly factor 1

decreases expression

cadmium sulfate results in decreased expression of NDUFAF1 mRNA

NCBI chr 3:106,639,025...106,650,549
Ensembl chr 3:106,639,851...106,650,212

G

NEDD4 E3 ubiquitin protein ligase

increases expression

cadmium sulfate results in increased expression of NEDD4 mRNA

PMID:12064557 PMID:14676411

NCBI chr 8:73,384,095...73,468,951
Ensembl chr 8:73,383,695...73,468,951

G

NEDD4 like E3 ubiquitin protein ligase

increases expression

cadmium sulfate results in increased expression of NEDD4L mRNA

NCBI chr18:58,393,759...58,726,709
Ensembl chr18:58,393,509...58,723,137

G

NIMA-related kinase 3

decreases expression

cadmium sulfate results in decreased expression of NEK3 mRNA

NCBI chr16:69,867,020...69,892,477
Ensembl chr16:69,867,047...69,892,508

G

nuclear receptor subfamily 2, group C, member 1

decreases expression

cadmium sulfate results in decreased expression of NR2C1 mRNA

NCBI chr 7:28,715,347...28,768,624
Ensembl chr 7:28,715,562...28,767,160

G

nuclear receptor subfamily 4, group A, member 1

increases expression

cadmium sulfate results in increased expression of NR4A1 mRNA

NCBI chr 7:132,368,399...132,389,300
Ensembl chr 7:132,374,840...132,389,297

G

nuclear casein kinase and cyclin-dependent kinase substrate 1

decreases expression

cadmium sulfate results in decreased expression of NUCKS1 mRNA

NCBI chr13:43,345,091...43,374,316
Ensembl chr13:43,345,115...43,370,229

G

nuclear transport factor 2-like export factor 2

increases expression

cadmium sulfate results in increased expression of NXT2 mRNA

NCBI chr X:105,855,616...105,862,902
Ensembl chr X:105,855,608...105,862,899

G

O-linked N-acetylglucosamine (GlcNAc) transferase

decreases expression

cadmium sulfate results in decreased expression of OGT mRNA

NCBI chr X:66,771,278...66,816,148
Ensembl chr X:66,771,349...66,816,146

G

progestin and adipoQ receptor family member 7

multiple interactions

cadmium sulfate affects the reaction [MTF1 affects the expression of PAQR7 mRNA]

NCBI chr 5:146,709,159...146,720,577
Ensembl chr 5:146,708,900...146,720,673

G

poly (ADP-ribose) polymerase 1

multiple interactions
increases cleavage

2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [cadmium sulfate results in increased cleavage of PARP1 protein]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [cadmium sulfate results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [cadmium sulfate results in increased cleavage of PARP1 protein]; diphenyleneiodonium inhibits the reaction [cadmium sulfate results in increased cleavage of PARP1 protein]

NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404

G

paired box 3

increases response to substance

PAX3 gene polymorphism results in increased susceptibility to cadmium sulfate

NCBI chr 9:79,567,455...79,664,042
Ensembl chr 9:79,568,634...79,664,042

G

PAX interacting protein 1

multiple interactions

cadmium sulfate affects the reaction [MTF1 affects the expression of PAXIP1 mRNA]

NCBI chr 4:7,525,132...7,576,659
Ensembl chr 4:7,525,004...7,576,548

G

phosphodiesterase 7A

multiple interactions

[cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of PDE7A mRNA

NCBI chr 2:101,714,767...101,806,853
Ensembl chr 2:101,718,444...101,806,681

G

platelet derived growth factor subunit A

multiple interactions

cadmium sulfate affects the reaction [MTF1 affects the expression of PDGFA mRNA]

NCBI chr12:15,645,549...15,667,056
Ensembl chr12:15,645,541...15,666,497

G

phosphofructokinase, platelet

increases expression

cadmium sulfate results in increased expression of PFKP mRNA

NCBI chr17:63,729,743...63,794,026
Ensembl chr17:63,729,780...63,794,018

G

profilin 2

decreases expression

cadmium sulfate results in decreased expression of PFN2 mRNA

NCBI chr 2:142,067,102...142,072,938
Ensembl chr 2:142,067,104...142,072,938

G

phosphogluconate dehydrogenase

increases expression

cadmium sulfate results in increased expression of PGD mRNA

NCBI chr 5:159,582,746...159,598,945
Ensembl chr 5:159,561,271...159,742,778

G

pleckstrin homology-like domain, family A, member 3

increases expression

cadmium sulfate results in increased expression of PHLDA3 mRNA

NCBI chr13:47,193,250...47,196,335
Ensembl chr13:47,193,086...47,196,335

G

pirin

increases expression

cadmium sulfate results in increased expression of PIR mRNA

NCBI chr X:30,108,536...30,219,269
Ensembl chr X:30,108,538...30,219,218

G

pyruvate kinase M1/2

multiple interactions

cadmium sulfate affects the reaction [MTF1 affects the expression of PKM mRNA]

NCBI chr 8:60,057,629...60,079,600
Ensembl chr 8:60,057,402...60,079,599

G

phospholipase A2 group 4A

multiple interactions

[cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of PLA2G4A mRNA
cadmium sulfate affects the reaction [MTF1 affects the expression of PLA2G4A mRNA]

PMID:16221973 PMID:18654764

NCBI chr13:61,877,818...62,022,261
Ensembl chr13:61,877,813...62,022,266

G

polo-like kinase 3

multiple interactions

cadmium sulfate affects the reaction [MTF1 affects the expression of PLK3 mRNA]

NCBI chr 5:130,607,142...130,612,317
Ensembl chr 5:130,607,142...130,612,317

G

procollagen lysine, 2-oxoglutarate 5-dioxygenase 2

increases expression

cadmium sulfate results in increased expression of PLOD2 mRNA

PMID:12064557 PMID:14676411

NCBI chr 8:93,084,548...93,167,255
Ensembl chr 8:93,084,513...93,167,255

G

phospholipid phosphatase 3

multiple interactions

cadmium sulfate affects the reaction [MTF1 affects the expression of PLPP3 mRNA]

NCBI chr 5:119,927,085...120,002,206
Ensembl chr 5:119,927,085...120,002,205

G

RNA polymerase I subunit H

decreases expression

cadmium sulfate results in decreased expression of POLR1H mRNA

NCBI chr20:1,594,936...1,598,854
Ensembl chr20:1,594,936...1,598,854

G

POU class 2 homeobox 1

multiple interactions

[cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] affects the expression of POU2F1 mRNA

NCBI chr13:78,120,617...78,263,306
Ensembl chr13:78,130,685...78,263,363

G

peroxisome proliferator-activated receptor gamma

multiple interactions

cadmium sulfate affects the reaction [MTF1 affects the expression of PPARG mRNA]

NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468

G

PPFIA binding protein 2

increases expression

cadmium sulfate results in increased expression of PPFIBP2 mRNA

NCBI chr 1:161,504,774...161,687,339
Ensembl chr 1:161,504,890...161,655,212

G

protein phosphatase, Mg2+/Mn2+ dependent, 1D

decreases expression

cadmium sulfate results in decreased expression of PPM1D mRNA

NCBI chr10:70,172,603...70,208,607
Ensembl chr10:70,172,603...70,208,607

G

protein kinase AMP-activated catalytic subunit alpha 2

multiple interactions

cadmium sulfate affects the reaction [MTF1 affects the expression of PRKAA2 mRNA]

NCBI chr 5:119,807,992...119,879,987
Ensembl chr 5:119,813,226...119,879,543

G

proline rich and Gla domain 2

increases expression

cadmium sulfate results in increased expression of PRRG2 mRNA

NCBI chr 1:95,534,276...95,543,364
Ensembl chr 1:95,534,290...95,543,425

G

serine protease 23

multiple interactions

cadmium sulfate affects the reaction [MTF1 affects the expression of PRSS23 mRNA]

NCBI chr 1:143,402,725...143,422,182
Ensembl chr 1:143,401,396...143,422,091

G

prostaglandin reductase 1

multiple interactions

[cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of PTGR1 mRNA

NCBI chr 5:73,784,000...73,802,624
Ensembl chr 5:73,784,009...73,802,666

G

prostaglandin-endoperoxide synthase 2

multiple interactions
increases expression

2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [cadmium sulfate results in increased expression of PTGS2]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [cadmium sulfate results in increased expression of PTGS2 protein]; [4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [cadmium sulfate results in increased expression of PTGS2 protein]] which results in decreased abundance of Dinoprostone; Acetylcysteine inhibits the reaction [cadmium sulfate results in increased expression of PTGS2]; diphenyleneiodonium inhibits the reaction [cadmium sulfate results in increased expression of PTGS2 protein]
cadmium sulfate results in increased expression of PTGS2; cadmium sulfate results in increased expression of PTGS2 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [cadmium sulfate results in increased expression of PTGS2 mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [cadmium sulfate results in increased expression of PTGS2 protein]; Acetylcysteine inhibits the reaction [cadmium sulfate results in increased expression of PTGS2 mRNA]; Acetylcysteine inhibits the reaction [cadmium sulfate results in increased expression of PTGS2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide inhibits the reaction [cadmium sulfate results in increased expression of PTGS2 protein]]; Cycloheximide inhibits the reaction [cadmium sulfate results in increased expression of PTGS2 protein]; Glutathione inhibits the reaction [cadmium sulfate results in increased expression of PTGS2 mRNA]; Glutathione inhibits the reaction [cadmium sulfate results in increased expression of PTGS2 protein]; pyrazolanthrone inhibits the reaction [cadmium sulfate results in increased expression of PTGS2 mRNA]; pyrazolanthrone inhibits the reaction [cadmium sulfate results in increased expression of PTGS2 protein]; SB 203580 inhibits the reaction [cadmium sulfate results in increased expression of PTGS2 mRNA]; SB 203580 inhibits the reaction [cadmium sulfate results in increased expression of PTGS2 protein]
cadmium sulfate results in increased expression of PTGS2 mRNA; cadmium sulfate results in increased expression of PTGS2 protein

PMID:14687664 PMID:22767315

NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188

G

parathyroid hormone 1 receptor

multiple interactions

cadmium sulfate inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of PTH1R mRNA]

NCBI chr 8:110,693,910...110,725,458
Ensembl chr 8:110,697,485...110,719,729

G

RAB29, member RAS oncogene family

multiple interactions

cadmium sulfate affects the reaction [MTF1 affects the expression of RAB29 mRNA]

NCBI chr13:43,307,757...43,313,420
Ensembl chr13:43,307,775...43,313,417

G

RAP2B, member of RAS oncogene family

multiple interactions

cadmium sulfate affects the reaction [MTF1 affects the expression of RAP2B mRNA]

NCBI chr 2:145,599,714...145,600,265
Ensembl chr 2:145,599,116...145,603,069

G

RAS p21 protein activator 1

decreases expression

cadmium sulfate results in decreased expression of RASA1 mRNA

NCBI chr 2:15,857,704...15,940,757
Ensembl chr 2:15,857,980...15,940,854

G

Ras association domain family member 6

increases expression

cadmium sulfate results in increased expression of RASSF6 mRNA

NCBI chr14:17,433,328...17,473,565
Ensembl chr14:17,442,789...17,473,330

G

RNA binding motif protein 15

decreases expression

cadmium sulfate results in decreased expression of RBM15 mRNA

NCBI chr 2:194,945,974...194,954,498
Ensembl chr 2:194,945,974...194,954,703

G

RNA binding motif protein 25

decreases expression

cadmium sulfate results in decreased expression of RBM25 mRNA

NCBI chr 6:103,271,775...103,319,090
Ensembl chr 6:103,271,801...103,317,854

G

regulatory factor X5

decreases expression

cadmium sulfate results in decreased expression of RFX5 mRNA

NCBI chr 2:182,521,191...182,528,720
Ensembl chr 2:182,521,202...182,528,717

G

regulator of cell cycle

multiple interactions

[cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of RGCC mRNA

NCBI chr15:54,662,483...54,675,320
Ensembl chr15:54,662,483...54,681,141

G

regulator of G-protein signaling 2

increases expression

cadmium sulfate results in increased expression of RGS2 mRNA

NCBI chr13:55,799,749...55,802,354
Ensembl chr13:55,798,829...55,802,385

G

ribonuclease A family member 4

multiple interactions

[cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of RNASE4 mRNA

NCBI chr15:24,312,765...24,330,112
Ensembl chr15:24,312,464...24,330,117

G

RNA polymerase II associated protein 3

decreases expression

cadmium sulfate results in decreased expression of RPAP3 mRNA

NCBI chr 7:128,810,820...128,840,006
Ensembl chr 7:128,810,827...128,839,950

G

retinoid X receptor gamma

multiple interactions
increases expression

cadmium sulfate affects the reaction [MTF1 affects the expression of RXRG mRNA]
cadmium sulfate results in increased expression of RXRG mRNA

PMID:12064557 PMID:14676411 PMID:16221973

NCBI chr13:79,743,430...79,785,173
Ensembl chr13:79,743,563...79,785,167

G

spermidine/spermine N1-acetyl transferase 1

increases expression

cadmium sulfate results in increased expression of SAT1 mRNA

NCBI chr X:40,158,354...40,161,641
Ensembl chr X:40,157,046...40,196,813

G

secretory carrier membrane protein 1

multiple interactions

[cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of SCAMP1 mRNA

NCBI chr 2:25,433,958...25,516,734
Ensembl chr 2:25,433,959...25,516,673

G

selenium binding protein 1

increases expression

cadmium sulfate results in increased expression of SELENBP1 mRNA

NCBI chr 2:182,494,004...182,504,594
Ensembl chr 2:182,493,978...182,504,594

G

selenoprotein W

multiple interactions

cadmium sulfate affects the reaction [MTF1 affects the expression of SELENOW mRNA]

NCBI chr 1:76,599,441...76,604,514
Ensembl chr 1:76,598,779...76,604,724
Ensembl chr 1:76,598,779...76,604,724

G

serpin family A member 9

increases expression

cadmium sulfate results in increased expression of SERPINA9 mRNA

NCBI chr 6:122,918,819...122,936,000
Ensembl chr 6:122,918,880...122,936,000

G

serpin family H member 1

multiple interactions

cadmium sulfate affects the reaction [MTF1 affects the expression of SERPINH1 mRNA]

NCBI chr 1:153,643,500...153,650,853
Ensembl chr 1:153,643,510...153,650,801

G

serum/glucocorticoid regulated kinase 1

decreases expression

cadmium sulfate results in decreased expression of SGK1 mRNA

NCBI chr 1:22,980,257...23,098,122
Ensembl chr 1:22,980,261...23,098,283

G

sphingosine-1-phosphate phosphatase 2

multiple interactions

cadmium sulfate affects the reaction [MTF1 affects the expression of SGPP2 mRNA]

NCBI chr 9:79,762,658...79,884,665
Ensembl chr 9:79,763,284...79,880,457

G

solute carrier family 25 member 25

multiple interactions

cadmium sulfate affects the reaction [MTF1 affects the expression of SLC25A25 mRNA]

NCBI chr 3:15,708,702...15,742,195
Ensembl chr 3:15,708,703...15,742,216

G

solute carrier family 38, member 1

increases expression

cadmium sulfate results in increased expression of SLC38A1 mRNA

PMID:12064557 PMID:14676411

NCBI chr 7:127,733,230...127,802,541
Ensembl chr 7:127,738,226...127,802,218

G

solute carrier family 39 member 10

multiple interactions

cadmium sulfate affects the reaction [MTF1 affects the expression of SLC39A10 mRNA]

NCBI chr 9:54,836,841...54,960,325
Ensembl chr 9:54,876,141...54,960,325

G

solute carrier family 39 member 8

affects expression

cadmium sulfate affects the expression of SLC39A8 mRNA

NCBI chr 2:224,171,787...224,319,326
Ensembl chr 2:224,256,654...224,319,129

G

solute carrier family 6 member 6

multiple interactions

[cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of SLC6A6 mRNA

NCBI chr 4:124,195,186...124,268,880
Ensembl chr 4:124,195,218...124,268,875

G

SMAD family member 7

multiple interactions

cadmium sulfate affects the reaction [MTF1 affects the expression of SMAD7 mRNA]

NCBI chr18:68,988,429...69,016,774
Ensembl chr18:68,988,429...69,016,765

G

structural maintenance of chromosomes 3

increases expression

cadmium sulfate results in increased expression of SMC3 mRNA

NCBI chr 1:252,601,422...252,644,522
Ensembl chr 1:252,601,753...252,644,522

G

syntrophin, gamma 2

decreases expression

cadmium sulfate results in decreased expression of SNTG2 mRNA

NCBI chr 6:46,801,893...47,003,390
Ensembl chr 6:46,801,377...47,003,372

G

superoxide dismutase 2

increases expression

cadmium sulfate results in increased expression of SOD2 mRNA

PMID:12064557 PMID:14676411

NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189

G

SRY-box transcription factor 2

increases expression

cadmium sulfate results in increased expression of SOX2 mRNA

NCBI chr 2:117,536,929...117,539,340
Ensembl chr 2:117,536,929...117,539,338

G

squalene epoxidase

multiple interactions

[cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of SQLE mRNA

NCBI chr 7:90,867,973...90,883,623
Ensembl chr 7:90,868,011...90,883,618

G

serum response factor

multiple interactions

[cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] affects the expression of SRF mRNA

NCBI chr 9:14,426,453...14,435,734
Ensembl chr 9:14,426,472...14,435,733

G

serine and arginine rich splicing factor 3

increases expression

cadmium sulfate results in increased expression of SRSF3 mRNA

NCBI chr20:7,091,928...7,101,860
Ensembl chr20:7,091,910...7,101,078

G

sulfiredoxin 1

increases expression

cadmium sulfate results in increased expression of SRXN1 mRNA

NCBI chr 3:140,604,490...140,610,050
Ensembl chr 3:140,599,608...140,628,448

G

sex determining region Y

multiple interactions

[cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] affects the expression of SRY mRNA

NCBI chr Y:441,525...442,037

G

ST18 C2H2C-type zinc finger transcription factor

decreases expression

cadmium sulfate results in decreased expression of ST18 mRNA

NCBI chr 5:12,582,493...12,914,221
Ensembl chr 5:12,584,110...12,671,790

G

stress-induced phosphoprotein 1

increases expression

cadmium sulfate results in increased expression of STIP1 mRNA

PMID:12064557 PMID:14676411

NCBI chr 1:204,209,433...204,228,452
Ensembl chr 1:204,178,932...204,228,476

G

serine/threonine kinase 26

multiple interactions

[cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of STK26 mRNA

NCBI chr X:130,325,064...130,375,674
Ensembl chr X:130,310,885...130,374,291

G

TATA-box binding protein like 1

decreases expression

cadmium sulfate results in decreased expression of TBPL1 mRNA

NCBI chr 1:22,777,892...22,803,305
Ensembl chr 1:22,778,459...22,803,122
Ensembl chr 1:22,778,459...22,803,122

G

TIMP metallopeptidase inhibitor 1

multiple interactions

cadmium sulfate affects the reaction [MTF1 affects the expression of TIMP1 mRNA]

NCBI chr X:1,212,969...1,217,714
Ensembl chr X:1,212,972...1,217,664

G

transmembrane protein 42

multiple interactions

cadmium sulfate affects the reaction [MTF1 affects the expression of TMEM42 mRNA]

NCBI chr 8:122,674,793...122,677,290
Ensembl chr 8:122,674,070...122,677,276

G

transmembrane protein 97

multiple interactions

[cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of TMEM97 mRNA

NCBI chr10:63,438,228...63,447,311
Ensembl chr10:63,438,222...63,589,730

G

tumor necrosis factor

increases secretion
multiple interactions

cadmium sulfate results in increased secretion of TNF protein
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [cadmium sulfate results in increased secretion of TNF protein]; U 0126 inhibits the reaction [cadmium sulfate results in increased secretion of TNF protein]

NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629

G

transportin 1

increases expression

cadmium sulfate results in increased expression of TNPO1 mRNA

PMID:12064557 PMID:14676411

NCBI chr 2:30,207,529...30,300,162
Ensembl chr 2:30,211,510...30,300,375

G

tetraspanin 7

multiple interactions

[cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of TSPAN7 mRNA

NCBI chr X:12,208,783...12,306,092
Ensembl chr X:12,208,783...12,306,131

G

tetratricopeptide repeat domain 4

multiple interactions

cadmium sulfate affects the reaction [MTF1 affects the expression of TTC4 mRNA]

NCBI chr 5:121,444,712...121,462,381
Ensembl chr 5:121,445,740...121,462,287

G

thioredoxin reductase 1

increases expression

cadmium sulfate results in increased expression of TXNRD1 mRNA

PMID:16221973 PMID:21783983

NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863

G

thymidylate synthetase

multiple interactions

[cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of TYMS mRNA

NCBI chr 9:113,313,454...113,329,551
Ensembl chr 9:113,313,452...113,329,536

G

ubiquitin B

increases expression

cadmium sulfate results in increased expression of UBB mRNA

PMID:12064557 PMID:14676411 PMID:21783983

NCBI chr10:47,247,630...47,249,335
Ensembl chr10:47,245,637...47,249,333

G

ubiquitin C

increases expression
multiple interactions

cadmium sulfate results in increased expression of UBC mRNA
cadmium sulfate affects the reaction [MTF1 affects the expression of UBC mRNA]

PMID:16221973 PMID:21783983

NCBI chr12:31,239,149...31,243,924
Ensembl chr12:31,239,152...31,243,925

G

ubiquitin protein ligase E3A

multiple interactions

cadmium sulfate affects the reaction [MTF1 affects the expression of UBE3A mRNA]

NCBI chr 1:110,070,260...110,161,675
Ensembl chr 1:110,070,480...110,157,250

G

ubiquilin 1

decreases expression

cadmium sulfate results in decreased expression of UBQLN1 mRNA

NCBI chr17:6,439,002...6,477,096
Ensembl chr17:6,439,002...6,477,090

G

upstream binding transcription factor

decreases expression

cadmium sulfate results in decreased expression of UBTF mRNA

NCBI chr10:87,258,217...87,274,291
Ensembl chr10:87,258,217...87,272,969

G

UDP-glucose 6-dehydrogenase

multiple interactions

[cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of UGDH mRNA

NCBI chr14:42,848,704...42,872,351
Ensembl chr14:42,848,854...42,872,354

G

uridine phosphorylase 2

multiple interactions

cadmium sulfate affects the reaction [MTF1 affects the expression of UPP2 mRNA]

NCBI chr 3:43,273,048...43,317,417
Ensembl chr 3:43,273,048...43,317,417

G

ubiquinol cytochrome c reductase core protein 2

decreases expression

cadmium sulfate results in decreased expression of UQCRC2 mRNA

NCBI chr 1:175,167,933...175,198,499
Ensembl chr 1:175,167,894...175,199,453

G

ubiquitin specific peptidase 24

multiple interactions

cadmium sulfate affects the reaction [MTF1 affects the expression of USP24 mRNA]

NCBI chr 5:121,080,687...121,210,321
Ensembl chr 5:121,080,470...121,210,311

G

vascular cell adhesion molecule 1

decreases expression

cadmium sulfate results in decreased expression of VCAM1 mRNA

NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958

G

vacuolar protein sorting 4 homolog A

decreases expression

cadmium sulfate results in decreased expression of VPS4A mRNA

NCBI chr19:34,934,999...34,948,888
Ensembl chr19:34,934,961...34,948,887

G

Wnt family member 11

multiple interactions

cadmium sulfate inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of WNT11 mRNA]

NCBI chr 1:153,134,503...153,154,294
Ensembl chr 1:153,138,197...153,154,294

G

Wnt family member 4

multiple interactions

[cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in decreased expression of WNT4 mRNA

NCBI chr 5:149,513,573...149,535,415
Ensembl chr 5:149,514,018...149,532,859

G

YY1 transcription factor

multiple interactions

[cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] affects the expression of YY1 mRNA

NCBI chr 6:127,706,739...127,736,499
Ensembl chr 6:127,707,596...127,732,747

G

zinc finger DHHC-type palmitoyltransferase 6

decreases expression

cadmium sulfate results in decreased expression of ZDHHC6 mRNA

NCBI chr 1:254,335,472...254,356,141
Ensembl chr 1:254,335,113...254,356,108

G

zinc finger protein 105

decreases expression

cadmium sulfate results in decreased expression of ZFP105 mRNA

NCBI chr 8:122,567,229...122,578,696
Ensembl chr 8:122,567,214...122,578,692

G

zinc finger protein 18

multiple interactions

cadmium sulfate affects the reaction [MTF1 affects the expression of ZKSCAN6 mRNA]

NCBI chr10:50,473,428...50,495,707
Ensembl chr10:50,473,483...50,495,706

G

zinc finger and SCAN domain containing 12

decreases expression

cadmium sulfate results in decreased expression of ZSCAN12 mRNA

NCBI chr17:43,247,250...43,253,206
Ensembl chr17:43,247,095...43,253,264

G

zinc finger and SCAN domain containing 26

decreases expression

cadmium sulfate results in decreased expression of ZSCAN26 mRNA

NCBI chr17:43,148,063...43,168,070
Ensembl chr17:43,148,079...43,168,070

Term paths to the root

Path 1
Term	Annotations
CHEBI ontology	19844
chemical entity	19842
molecular entity	19842
transition element molecular entity	16829
d-block molecular entity	16839
zinc group molecular entity	11774
cadmium molecular entity	7713
cadmium salt	280
cadmium sulfate	275
cadmium sulfate hydrate	0
Path 2
Term	Annotations
CHEBI ontology	19844
subatomic particle	19842
composite particle	19842
hadron	19842
baryon	19842
nucleon	19809
atomic nucleus	19842
atom	19842
metal atom	17724
transition element atom	17091
d-block element atom	17084
d-block molecular entity	16839
zinc group molecular entity	11774
cadmium molecular entity	7713
cadmium salt	280
cadmium sulfate	275
cadmium sulfate hydrate	0

paths to the root