CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: 2-bromocarboxylic acid
Accession: CHEBI:134367
browse the term
Definition: Any carboxylic acid in which the carbon bearing the carboxy group is substituted by a bromine.
Synonyms: related_synonym: 2-bromocarboxylic acids; Formula=C2H2BrO2R; SMILES=OC(C(Br)*)=O; alpha-bromocarboxylic acid; alpha-bromocarboxylic acids
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Apoa1
apolipoprotein A1
decreases expression
EXP
2-bromopalmitate results in decreased expression of APOA1 mRNA
CTD
PMID:7556148
NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
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Cebpb
CCAAT/enhancer binding protein beta
multiple interactions
ISO
2-bromopalmitate promotes the reaction [Tretinoin results in increased expression of CEBPB mRNA]
CTD
PMID:30076181
NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
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Fas
Fas cell surface death receptor
decreases expression
ISO
2-bromopalmitate results in decreased expression of FAS mRNA
CTD
PMID:16712844
NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
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Gapdh
glyceraldehyde-3-phosphate dehydrogenase
increases activity
EXP
2-bromopalmitate results in increased activity of GAPDH protein
CTD
PMID:10650946
NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235
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Ifit3
interferon-induced protein with tetratricopeptide repeats 3
multiple interactions
ISO
2-bromopalmitate promotes the reaction [Tretinoin results in increased expression of IFIT3 mRNA]
CTD
PMID:30076181
NCBI chr 1:232,114,166...232,119,311
Ensembl chr 1:232,114,166...232,119,307
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Irf1
interferon regulatory factor 1
multiple interactions
ISO
2-bromopalmitate promotes the reaction [Tretinoin results in increased expression of IRF1 mRNA]
CTD
PMID:30076181
NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166
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Lat2
linker for activation of T cells family, member 2
decreases expression
ISO
2-bromopalmitate results in decreased expression of LAT2 protein
CTD
PMID:23001822
NCBI chr12:22,104,173...22,118,294
Ensembl chr12:22,104,219...22,118,288
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Ldlr
low density lipoprotein receptor
increases expression
ISO
2-bromopalmitate results in increased expression of LDLR mRNA
CTD
PMID:23150725
NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
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Lrat
lecithin retinol acyltransferase
increases expression
EXP
2-bromopalmitate results in increased expression of LRAT mRNA
CTD
PMID:12576510
NCBI chr 2:168,264,093...168,273,155
Ensembl chr 2:168,266,877...168,273,619
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Ly6e
lymphocyte antigen 6 family member E
multiple interactions
ISO
2-bromopalmitate promotes the reaction [Tretinoin results in increased expression of LY6E mRNA]
CTD
PMID:30076181
NCBI chr 7:106,935,530...106,939,689
Ensembl chr 7:106,935,761...106,939,689
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Mpo
myeloperoxidase
multiple interactions
ISO
2-bromopalmitate promotes the reaction [Tretinoin results in decreased expression of MPO mRNA]
CTD
PMID:30076181
NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
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Ppard
peroxisome proliferator-activated receptor delta
increases activity multiple interactions
ISO
2-bromopalmitate results in increased activity of PPARD protein 2-bromopalmitate results in increased activity of [RXRA protein binds to PPARD protein]
CTD
PMID:15997096 PMID:21543282 PMID:23150725
NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968
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Pparg
peroxisome proliferator-activated receptor gamma
increases expression
EXP
2-bromopalmitate results in increased expression of PPARG protein
CTD
PMID:10650946
NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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Rara
retinoic acid receptor, alpha
multiple interactions
ISO
2-bromopalmitate binds to and results in increased expression of RARA protein; 2-bromopalmitate inhibits the reaction [Am 580 results in decreased expression of RARA protein]; 2-bromopalmitate inhibits the reaction [Tretinoin results in decreased expression of RARA protein]; [2-bromopalmitate results in increased susceptibility to Tretinoin] which results in increased expression of RARA protein
CTD
PMID:30076181
NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142
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Rarb
retinoic acid receptor, beta
multiple interactions
ISO
2-bromopalmitate promotes the reaction [Tretinoin results in increased expression of RARB mRNA]
CTD
PMID:30076181
NCBI chr15:8,700,533...9,051,288
Ensembl chr15:8,406,492...9,051,288
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Rbp1
retinol binding protein 1
increases expression
EXP
2-bromopalmitate results in increased expression of RBP1 mRNA
CTD
PMID:12576510
NCBI chr 8:99,025,218...99,046,740
Ensembl chr 8:99,025,206...99,046,743
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Rxra
retinoid X receptor alpha
multiple interactions
ISO
2-bromopalmitate results in increased activity of [RXRA protein binds to PPARD protein]
CTD
PMID:15997096
NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712
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Spi1
Spi-1 proto-oncogene
multiple interactions
ISO
2-bromopalmitate promotes the reaction [Tretinoin results in increased expression of SPI1 mRNA]
CTD
PMID:30076181
NCBI chr 3:77,059,744...77,093,730
Ensembl chr 3:77,073,012...77,092,393
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Tgm2
transglutaminase 2
multiple interactions
ISO
2-bromopalmitate promotes the reaction [Tretinoin results in increased expression of TGM2 mRNA]
CTD
PMID:30076181
NCBI chr 3:146,772,684...146,801,924
Ensembl chr 3:146,772,687...146,801,981
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Ucp2
uncoupling protein 2
increases expression
EXP
2-bromopalmitate results in increased expression of UCP2 mRNA
CTD
PMID:11341955
NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611
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Actb
actin, beta
increases expression
ISO
bromochloroacetic acid results in increased expression of ACTB protein
CTD
PMID:21296659
NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877
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Actg2
actin gamma 2, smooth muscle
decreases expression
EXP
bromochloroacetic acid results in decreased expression of ACTG2 mRNA
CTD
PMID:16460773
NCBI chr 4:116,021,832...116,046,475
Ensembl chr 4:116,021,832...116,046,465
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Actn1
actinin, alpha 1
decreases expression
EXP
bromochloroacetic acid results in decreased expression of ACTN1 mRNA
CTD
PMID:16460773
NCBI chr 6:98,998,553...99,093,334
Ensembl chr 6:98,998,556...99,093,251
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Actn4
actinin alpha 4
decreases expression
EXP
bromochloroacetic acid results in decreased expression of ACTN4 mRNA
CTD
PMID:16460773
NCBI chr 1:84,182,783...84,251,867
Ensembl chr 1:84,182,788...84,251,847
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Afp
alpha-fetoprotein
decreases expression
ISO
bromochloroacetic acid results in decreased expression of AFP protein
CTD
PMID:21296659
NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480
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Akt2
AKT serine/threonine kinase 2
increases expression
EXP
bromochloroacetic acid results in increased expression of AKT2 mRNA
CTD
PMID:16460773
NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817
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Arf4
ADP-ribosylation factor 4
decreases expression
EXP
bromochloroacetic acid results in decreased expression of ARF4 mRNA
CTD
PMID:16460773
NCBI chr16:1,896,692...1,913,267
Ensembl chr16:1,896,546...1,913,261
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Bnip3l
BCL2 interacting protein 3 like
increases expression
EXP
bromochloroacetic acid results in increased expression of BNIP3L mRNA
CTD
PMID:16460773
NCBI chr15:41,174,594...41,197,730
Ensembl chr15:41,174,594...41,197,803
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Ccn3
cellular communication network factor 3
decreases expression
EXP
bromochloroacetic acid results in decreased expression of CCN3 mRNA
CTD
PMID:16460773
NCBI chr 7:86,094,000...86,101,022
Ensembl chr 7:86,094,000...86,101,019
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Cd34
CD34 molecule
decreases expression
ISO
bromochloroacetic acid results in decreased expression of CD34 protein
CTD
PMID:21296659
NCBI chr13:106,480,313...106,500,844
Ensembl chr13:106,480,043...106,499,832
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Cdkn1a
cyclin-dependent kinase inhibitor 1A
decreases expression
EXP
bromochloroacetic acid results in decreased expression of CDKN1A mRNA
CTD
PMID:16460773
NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
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Cdx2
caudal type homeo box 2
increases expression
ISO
bromochloroacetic acid results in increased expression of CDX2 protein
CTD
PMID:21296659
NCBI chr12:7,726,798...7,733,142
Ensembl chr12:7,726,798...7,733,142
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Col1a1
collagen type I alpha 1 chain
decreases expression
ISO
bromochloroacetic acid results in decreased expression of COL1A1 protein
CTD
PMID:21296659
NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
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Col1a2
collagen type I alpha 2 chain
decreases expression
EXP
bromochloroacetic acid results in decreased expression of COL1A2 mRNA
CTD
PMID:16460773
NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867
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Col2a1
collagen type II alpha 1 chain
decreases expression
ISO
bromochloroacetic acid results in decreased expression of COL2A1 protein
CTD
PMID:21296659
NCBI chr 7:129,098,489...129,127,560
Ensembl chr 7:129,098,786...129,127,546
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Crabp2
cellular retinoic acid binding protein 2
increases expression
ISO
bromochloroacetic acid results in increased expression of CRABP2 protein
CTD
PMID:21296659
NCBI chr 2:173,417,004...173,421,352
Ensembl chr 2:173,416,857...173,421,379
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Cripto
cripto, EGF-CFC family member
increases expression
ISO
bromochloroacetic acid results in increased expression of CRIPTO protein
CTD
PMID:21296659
NCBI chr 8:110,924,774...110,938,545
Ensembl chr 8:110,925,024...110,930,308
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Ddx4
DEAD-box helicase 4
decreases expression
ISO
bromochloroacetic acid results in decreased expression of DDX4 protein
CTD
PMID:21296659
NCBI chr 2:44,227,946...44,282,867
Ensembl chr 2:44,227,946...44,282,723
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Dnmt3b
DNA methyltransferase 3 beta
decreases expression
ISO
bromochloroacetic acid results in decreased expression of DNMT3B protein
CTD
PMID:21296659
NCBI chr 3:142,130,588...142,169,128
Ensembl chr 3:142,130,592...142,169,124
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Eef1a1
eukaryotic translation elongation factor 1 alpha 1
increases expression
ISO
bromochloroacetic acid results in increased expression of EEF1A1 protein
CTD
PMID:21296659
NCBI chr 8:79,341,554...79,344,784
Ensembl chr 8:79,341,557...79,344,839
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Eomes
eomesodermin
decreases expression
ISO
bromochloroacetic acid results in decreased expression of EOMES protein
CTD
PMID:21296659
NCBI chr 8:118,181,340...118,189,186
Ensembl chr 8:118,181,777...118,188,316
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Eras
ES cell expressed Ras
increases expression
ISO
bromochloroacetic acid results in increased expression of ERAS protein
CTD
PMID:21296659
NCBI chr X:14,573,987...14,578,455
Ensembl chr X:14,573,987...14,578,374
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Fas
Fas cell surface death receptor
decreases expression
EXP
bromochloroacetic acid results in decreased expression of FAS mRNA
CTD
PMID:16460773
NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
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Fat1
FAT atypical cadherin 1
decreases expression
EXP
bromochloroacetic acid results in decreased expression of FAT1 mRNA
CTD
PMID:16460773
NCBI chr16:47,177,253...47,296,261
Ensembl chr16:47,177,248...47,296,107
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Fgf4
fibroblast growth factor 4
increases expression
ISO
bromochloroacetic acid results in increased expression of FGF4 protein
CTD
PMID:21296659
NCBI chr 1:200,023,937...200,027,793
Ensembl chr 1:200,024,056...200,025,466
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Fgf5
fibroblast growth factor 5
increases expression
ISO
bromochloroacetic acid results in increased expression of FGF5 protein
CTD
PMID:21296659
NCBI chr14:11,323,827...11,346,164
Ensembl chr14:11,325,334...11,345,997
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Flt1
Fms related receptor tyrosine kinase 1
decreases expression
ISO
bromochloroacetic acid results in decreased expression of FLT1 protein
CTD
PMID:21296659
NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626
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Fn1
fibronectin 1
increases expression
ISO
bromochloroacetic acid results in increased expression of FN1 protein
CTD
PMID:21296659
NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
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Fos
Fos proto-oncogene, AP-1 transcription factor subunit
decreases expression
EXP
bromochloroacetic acid results in decreased expression of FOS mRNA
CTD
PMID:16460773
NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
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Fosl1
FOS like 1, AP-1 transcription factor subunit
decreases expression
EXP
bromochloroacetic acid results in decreased expression of FOSL1 mRNA
CTD
PMID:16460773
NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930
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Foxa2
forkhead box A2
affects expression
ISO
bromochloroacetic acid affects the expression of FOXA2 protein
CTD
PMID:21296659
NCBI chr 3:135,470,123...135,474,326
Ensembl chr 3:135,470,131...135,474,326
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Fzd2
frizzled class receptor 2
decreases expression
EXP
bromochloroacetic acid results in decreased expression of FZD2 mRNA
CTD
PMID:16460773
NCBI chr10:87,561,866...87,563,776
Ensembl chr10:87,561,326...87,565,334
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Gabrb3
gamma-aminobutyric acid type A receptor subunit beta 3
affects expression
ISO
bromochloroacetic acid affects the expression of GABRB3 protein
CTD
PMID:21296659
NCBI chr 1:108,467,047...108,702,522
Ensembl chr 1:108,296,124...108,698,961
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Gadd45a
growth arrest and DNA-damage-inducible, alpha
decreases expression
EXP
bromochloroacetic acid results in decreased expression of GADD45A mRNA
CTD
PMID:16460773
NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
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Gal
galanin and GMAP prepropeptide
increases expression
ISO
bromochloroacetic acid results in increased expression of GAL protein
CTD
PMID:21296659
NCBI chr 1:200,650,439...200,655,302
Ensembl chr 1:200,650,439...200,654,959
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Gapdh
glyceraldehyde-3-phosphate dehydrogenase
increases expression
ISO
bromochloroacetic acid results in increased expression of GAPDH protein
CTD
PMID:21296659
NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235
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Gata6
GATA binding protein 6
increases expression
ISO
bromochloroacetic acid results in increased expression of GATA6 protein
CTD
PMID:21296659
NCBI chr18:2,188,121...2,219,532
Ensembl chr18:2,188,121...2,219,532
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Gbx2
gastrulation brain homeobox 2
increases expression
ISO
bromochloroacetic acid results in increased expression of GBX2 protein
CTD
PMID:21296659
NCBI chr 9:90,509,633...90,512,212
Ensembl chr 9:90,509,633...90,512,212
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Gcm1
glial cells missing transcription factor 1
increases expression
ISO
bromochloroacetic acid results in increased expression of GCM1 protein
CTD
PMID:21296659
NCBI chr 8:78,925,687...78,938,924
Ensembl chr 8:78,925,687...78,938,924
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Gdf3
growth differentiation factor 3
increases expression
ISO
bromochloroacetic acid results in increased expression of GDF3 protein
CTD
PMID:21296659
NCBI chr 4:155,831,572...155,835,953
Ensembl chr 4:155,830,909...155,835,937
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Gfap
glial fibrillary acidic protein
decreases expression
ISO
bromochloroacetic acid results in decreased expression of GFAP protein
CTD
PMID:21296659
NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589
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Gnaq
G protein subunit alpha q
decreases expression
EXP
bromochloroacetic acid results in decreased expression of GNAQ mRNA
CTD
PMID:16460773
NCBI chr 1:213,425,631...213,671,947
Ensembl chr 1:213,424,465...213,667,672
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Grb7
growth factor receptor bound protein 7
increases expression
ISO
bromochloroacetic acid results in increased expression of GRB7 protein
CTD
PMID:21296659
NCBI chr10:83,443,387...83,453,057
Ensembl chr10:83,444,004...83,453,052
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Gsk3b
glycogen synthase kinase 3 beta
affects expression
EXP
bromochloroacetic acid affects the expression of GSK3B mRNA
CTD
PMID:16460773
NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
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Hbb-b2
hemoglobin, beta adult minor chain
affects expression
ISO
bromochloroacetic acid affects the expression of HBB-B2 protein
CTD
PMID:21296659
NCBI chr 1:158,243,696...158,245,076
Ensembl chr 1:158,120,200...158,252,012
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Hbz
hemoglobin subunit zeta
increases expression
ISO
bromochloroacetic acid results in increased expression of HBZ protein
CTD
PMID:21296659
NCBI chr10:15,343,821...15,345,301
Ensembl chr10:15,343,831...15,345,312
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Iapp
islet amyloid polypeptide
decreases expression
ISO
bromochloroacetic acid results in decreased expression of IAPP protein
CTD
PMID:21296659
NCBI chr 4:175,237,107...175,244,373
Ensembl chr 4:175,237,115...175,242,920
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Ifitm1
interferon induced transmembrane protein 1
increases expression
ISO
bromochloroacetic acid results in increased expression of IFITM1 protein
CTD
PMID:21296659
NCBI chr 1:196,067,163...196,069,169
Ensembl chr 1:196,067,963...196,069,169
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Ifitm2
interferon induced transmembrane protein 2
decreases expression
ISO
bromochloroacetic acid results in decreased expression of IFITM2 protein
CTD
PMID:21296659
NCBI chr 1:196,051,539...196,052,719
Ensembl chr 1:196,051,537...196,052,741
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Igf1
insulin-like growth factor 1
increases expression
EXP
bromochloroacetic acid results in increased expression of IGF1 mRNA
CTD
PMID:16460773
NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
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Igfbp2
insulin-like growth factor binding protein 2
increases expression
EXP ISO
bromochloroacetic acid results in increased expression of IGFBP2 mRNA bromochloroacetic acid results in increased expression of IGFBP2 protein
CTD
PMID:16460773 PMID:21296659
NCBI chr 9:74,415,574...74,442,945
Ensembl chr 9:74,415,546...74,442,937
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Igfbp3
insulin-like growth factor binding protein 3
increases expression
EXP
bromochloroacetic acid results in increased expression of IGFBP3 mRNA
CTD
PMID:16460773
NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083
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Igfbp6
insulin-like growth factor binding protein 6
increases expression
EXP
bromochloroacetic acid results in increased expression of IGFBP6 mRNA
CTD
PMID:16460773
NCBI chr 7:133,276,309...133,280,944
Ensembl chr 7:133,276,234...133,280,966
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Il6st
interleukin 6 cytokine family signal transducer
increases expression
ISO
bromochloroacetic acid results in increased expression of IL6ST protein
CTD
PMID:21296659
NCBI chr 2:44,065,979...44,106,255
Ensembl chr 2:44,066,130...44,109,936
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Ilk
integrin-linked kinase
decreases expression
EXP
bromochloroacetic acid results in decreased expression of ILK mRNA
CTD
PMID:16460773
NCBI chr 1:160,088,839...160,095,140
Ensembl chr 1:160,088,897...160,095,140
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Ins2
insulin 2
decreases expression
ISO
bromochloroacetic acid results in decreased expression of INS2 protein
CTD
PMID:21296659
NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
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Itga8
integrin subunit alpha 8
decreases expression
EXP
bromochloroacetic acid results in decreased expression of ITGA8 mRNA
CTD
PMID:16460773
NCBI chr17:75,304,004...75,501,510
Ensembl chr17:75,304,008...75,501,510
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Itgb1
integrin subunit beta 1
decreases expression
EXP
bromochloroacetic acid results in decreased expression of ITGB1 mRNA
CTD
PMID:16460773
NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195
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Itgb2
integrin subunit beta 2
increases expression
EXP
bromochloroacetic acid results in increased expression of ITGB2 mRNA
CTD
PMID:16460773
NCBI chr20:11,061,394...11,097,656
Ensembl chr20:11,061,430...11,097,600
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Kit
KIT proto-oncogene receptor tyrosine kinase
decreases expression
ISO
bromochloroacetic acid results in decreased expression of KIT protein
CTD
PMID:21296659
NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652
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Krt1
keratin 1
decreases expression
ISO
bromochloroacetic acid results in decreased expression of KRT1 protein
CTD
PMID:21296659
NCBI chr 7:132,976,618...132,981,844
Ensembl chr 7:132,976,620...132,981,844
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Lama1
laminin subunit alpha 1
increases expression
ISO
bromochloroacetic acid results in increased expression of LAMA1 protein
CTD
PMID:21296659
NCBI chr 9:107,692,770...107,816,847
Ensembl chr 9:107,692,770...107,817,478
G
Lamb1
laminin subunit beta 1
decreases expression
ISO
bromochloroacetic acid results in decreased expression of LAMB1 protein
CTD
PMID:21296659
NCBI chr 6:47,835,492...47,902,585
Ensembl chr 6:47,835,525...47,902,585
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Lamc1
laminin subunit gamma 1
increases expression
ISO
bromochloroacetic acid results in increased expression of LAMC1 protein
CTD
PMID:21296659
NCBI chr13:65,374,372...65,501,492
Ensembl chr13:65,374,372...65,501,492
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Lefty1
left right determination factor 1
affects expression
ISO
bromochloroacetic acid affects the expression of LEFTY1 protein
CTD
PMID:21296659
NCBI chr13:92,649,226...92,659,722
Ensembl chr13:92,656,323...92,659,720
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Lifr
LIF receptor subunit alpha
increases expression
ISO
bromochloroacetic acid results in increased expression of LIFR protein
CTD
PMID:21296659
NCBI chr 2:56,224,393...56,292,988
Ensembl chr 2:56,250,120...56,286,699
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Lin28a
lin-28 homolog A
decreases expression
ISO
bromochloroacetic acid results in decreased expression of LIN28A protein
CTD
PMID:21296659
NCBI chr 5:146,227,119...146,244,122
Ensembl chr 5:146,227,119...146,244,122
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Mapkapk2
MAPK activated protein kinase 2
increases expression
EXP
bromochloroacetic acid results in increased expression of MAPKAPK2 mRNA
CTD
PMID:16460773
NCBI chr13:42,513,762...42,560,061
Ensembl chr13:42,513,762...42,560,457
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Mnx1
motor neuron and pancreas homeobox 1
decreases expression
ISO
bromochloroacetic acid results in decreased expression of MNX1 protein
CTD
PMID:21296659
NCBI chr 4:5,866,506...5,871,465
Ensembl chr 4:5,866,506...5,871,465
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Msln
mesothelin
increases expression
EXP
bromochloroacetic acid results in increased expression of MSLN mRNA
CTD
PMID:16460773
NCBI chr10:14,771,946...14,781,382
Ensembl chr10:14,771,961...14,777,643
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Myc
MYC proto-oncogene, bHLH transcription factor
increases expression
EXP
bromochloroacetic acid results in increased expression of MYC mRNA
CTD
PMID:16460773
NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
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Myf5
myogenic factor 5
decreases expression
ISO
bromochloroacetic acid results in decreased expression of MYF5 protein
CTD
PMID:21296659
NCBI chr 7:42,802,946...42,806,177
Ensembl chr 7:42,802,946...42,806,177
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Myod1
myogenic differentiation 1
decreases expression
ISO
bromochloroacetic acid results in decreased expression of MYOD1 protein
CTD
PMID:21296659
NCBI chr 1:96,884,864...96,887,574
Ensembl chr 1:96,884,948...96,887,554
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Nanog
Nanog homeobox
increases expression
ISO
bromochloroacetic acid results in increased expression of NANOG protein
CTD
PMID:21296659
NCBI chr 4:155,943,737...155,951,116
Ensembl chr 4:155,943,737...155,951,116
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Neurod1
neuronal differentiation 1
increases expression
ISO
bromochloroacetic acid results in increased expression of NEUROD1 protein
CTD
PMID:21296659
NCBI chr 3:64,359,554...64,363,526
Ensembl chr 3:64,359,395...64,363,649
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Nodal
nodal growth differentiation factor
affects expression
ISO
bromochloroacetic acid affects the expression of NODAL protein
CTD
PMID:21296659
NCBI chr20:29,368,436...29,376,837
Ensembl chr20:29,368,436...29,376,837
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Nog
noggin
increases expression
ISO
bromochloroacetic acid results in increased expression of NOG protein
CTD
PMID:21296659
NCBI chr10:74,128,712...74,130,339
Ensembl chr10:74,128,712...74,130,339
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Nppa
natriuretic peptide A
increases expression
ISO
bromochloroacetic acid results in increased expression of NPPA protein
CTD
PMID:21296659
NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351
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Nr5a2
nuclear receptor subfamily 5, group A, member 2
increases expression
ISO
bromochloroacetic acid results in increased expression of NR5A2 protein
CTD
PMID:21296659
NCBI chr13:48,313,634...48,433,494
Ensembl chr13:48,316,301...48,433,326
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Nras
NRAS proto-oncogene, GTPase
increases expression
EXP
bromochloroacetic acid results in increased expression of NRAS mRNA
CTD
PMID:16460773
NCBI chr 2:190,582,885...190,593,509
Ensembl chr 2:190,582,918...190,591,626
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Olig2
oligodendrocyte transcription factor 2
decreases expression
ISO
bromochloroacetic acid results in decreased expression of OLIG2 protein
CTD
PMID:21296659
NCBI chr11:30,475,510...30,478,886
Ensembl chr11:30,475,398...30,480,152
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Pax6
paired box 6
increases expression
ISO
bromochloroacetic acid results in increased expression of PAX6 protein
CTD
PMID:21296659
NCBI chr 3:92,128,772...92,157,022
Ensembl chr 3:92,135,637...92,157,014
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Pdx1
pancreatic and duodenal homeobox 1
decreases expression
ISO
bromochloroacetic acid results in decreased expression of IPF1 protein
CTD
PMID:21296659
NCBI chr12:7,757,865...7,763,064
Ensembl chr12:7,757,865...7,763,064
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Podxl
podocalyxin-like
increases expression
ISO
bromochloroacetic acid results in increased expression of PODXL protein
CTD
PMID:21296659
NCBI chr 4:60,135,124...60,181,829
Ensembl chr 4:60,135,109...60,181,899
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Pou5f1
POU class 5 homeobox 1
increases expression
ISO
bromochloroacetic acid results in increased expression of POU5F1 protein
CTD
PMID:21296659
NCBI chr20:3,223,128...3,227,891
Ensembl chr20:3,223,129...3,227,891
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Ppp1r12a
protein phosphatase 1, regulatory subunit 12A
decreases expression
EXP
bromochloroacetic acid results in decreased expression of PPP1R12A mRNA
CTD
PMID:16460773
NCBI chr 7:43,482,808...43,593,689
Ensembl chr 7:43,482,803...43,593,425
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Ppp2r2b
protein phosphatase 2, regulatory subunit B, beta
increases expression
EXP
bromochloroacetic acid results in increased expression of PPP2R2B mRNA
CTD
PMID:16460773
NCBI chr18:34,653,716...35,080,889
Ensembl chr18:34,653,721...35,081,025
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Prkcz
protein kinase C, zeta
increases expression
EXP
bromochloroacetic acid results in increased expression of PRKCZ mRNA
CTD
PMID:16460773
NCBI chr 5:165,817,786...165,930,386
Ensembl chr 5:165,819,466...165,930,367
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Rala
RAS like proto-oncogene A
decreases expression
EXP
bromochloroacetic acid results in decreased expression of RALA mRNA
CTD
PMID:16460773
NCBI chr17:47,092,163...47,145,192
Ensembl chr17:47,092,207...47,144,063
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Rest
RE1-silencing transcription factor
decreases expression
ISO
bromochloroacetic acid results in decreased expression of REST protein
CTD
PMID:21296659
NCBI chr14:30,859,109...30,879,828
Ensembl chr14:30,862,553...30,894,354
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Sema3a
semaphorin 3A
decreases expression
ISO
bromochloroacetic acid results in decreased expression of SEMA3A protein
CTD
PMID:21296659
NCBI chr 4:21,282,398...21,754,834
Ensembl chr 4:21,287,982...21,494,432
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Sfrp2
secreted frizzled-related protein 2
decreases expression
ISO
bromochloroacetic acid results in decreased expression of SFRP2 protein
CTD
PMID:21296659
NCBI chr 2:169,089,517...169,097,064
Ensembl chr 2:169,089,517...169,097,063
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Sox17
SRY-box transcription factor 17
decreases expression
ISO
bromochloroacetic acid results in decreased expression of SOX17 protein
CTD
PMID:21296659
NCBI chr 5:15,016,660...15,022,228
Ensembl chr 5:15,016,731...15,022,228
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Sox2
SRY-box transcription factor 2
affects expression
ISO
bromochloroacetic acid affects the expression of SOX2 protein
CTD
PMID:21296659
NCBI chr 2:117,536,929...117,539,340
Ensembl chr 2:117,536,929...117,539,338
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Sst
somatostatin
increases expression
ISO
bromochloroacetic acid results in increased expression of SST protein
CTD
PMID:21296659
NCBI chr11:76,956,896...76,958,173
Ensembl chr11:76,956,896...76,958,173
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Sycp3
synaptonemal complex protein 3
decreases expression
ISO
bromochloroacetic acid results in decreased expression of SYCP3 protein
CTD
PMID:21296659
NCBI chr 7:22,874,055...22,888,512
Ensembl chr 7:22,874,055...22,888,511
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Syp
synaptophysin
decreases expression
ISO
bromochloroacetic acid results in decreased expression of SYP protein
CTD
PMID:21296659
NCBI chr X:14,849,444...14,864,553
Ensembl chr X:14,849,444...14,864,745
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Tat
tyrosine aminotransferase
decreases expression
ISO
bromochloroacetic acid results in decreased expression of TAT protein
CTD
PMID:21296659
NCBI chr19:37,947,153...37,957,717
Ensembl chr19:37,947,112...37,958,031
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Tbxt
T-box transcription factor T
increases expression
ISO
bromochloroacetic acid results in increased expression of T protein
CTD
PMID:21296659
NCBI chr 1:52,298,104...52,309,813
Ensembl chr 1:52,298,099...52,305,864
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Tert
telomerase reverse transcriptase
increases expression
ISO
bromochloroacetic acid results in increased expression of TERT protein
CTD
PMID:21296659
NCBI chr 1:29,637,213...29,659,561
Ensembl chr 1:29,637,506...29,659,561
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Tgfb2
transforming growth factor, beta 2
decreases expression
EXP
bromochloroacetic acid results in decreased expression of TGFB2 mRNA
CTD
PMID:16460773
NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405
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Tgfb3
transforming growth factor, beta 3
decreases expression
EXP
bromochloroacetic acid results in decreased expression of TGFB3 mRNA
CTD
PMID:16460773
NCBI chr 6:105,704,058...105,726,661
Ensembl chr 6:105,704,236...105,726,564
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Tgfbr2
transforming growth factor, beta receptor 2
increases expression
EXP
bromochloroacetic acid results in increased expression of TGFBR2 mRNA
CTD
PMID:16460773
NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228
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Th
tyrosine hydroxylase
affects expression
ISO
bromochloroacetic acid affects the expression of TH protein
CTD
PMID:21296659
NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767
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Tp53
tumor protein p53
multiple interactions
EXP
bromochloroacetic acid promotes the reaction [Bromates results in increased phosphorylation of TP53 protein]
CTD
PMID:21864635
NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
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Utf1
undifferentiated embryonic cell transcription factor 1
affects expression
ISO
bromochloroacetic acid affects the expression of UTF1 protein
CTD
PMID:21296659
NCBI chr 1:194,740,339...194,741,465
Ensembl chr 1:194,740,339...194,741,465
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Wnt4
Wnt family member 4
increases expression
EXP
bromochloroacetic acid results in increased expression of WNT4 mRNA
CTD
PMID:16460773
NCBI chr 5:149,513,573...149,535,415
Ensembl chr 5:149,514,018...149,532,859
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Wt1
WT1 transcription factor
decreases expression
ISO
bromochloroacetic acid results in decreased expression of WT1 protein
CTD
PMID:21296659
NCBI chr 3:91,566,540...91,613,653
Ensembl chr 3:91,567,001...91,613,643
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Xist
X inactive specific transcript
decreases expression
ISO
bromochloroacetic acid results in decreased expression of XIST protein
CTD
PMID:21296659
NCBI chr X:68,474,987...68,492,500
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Zfp42
zinc finger protein 42
increases expression
ISO
bromochloroacetic acid results in increased expression of ZFP42 protein
CTD
PMID:21296659
NCBI chr16:48,836,463...48,845,443
Ensembl chr16:48,836,648...48,845,401
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Atf2
activating transcription factor 2
increases expression
ISO
dibromoacetic acid results in increased expression of ATF2 mRNA
CTD
PMID:29155130
NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236
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Bcl2
BCL2, apoptosis regulator
decreases expression
ISO
dibromoacetic acid results in decreased expression of BCL2 mRNA
CTD
PMID:18628252
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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Casp3
caspase 3
increases expression
ISO
dibromoacetic acid results in increased expression of CASP3 protein modified form
CTD
PMID:29155130
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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Ces3a
carboxylesterase 3a
decreases expression
EXP
dibromoacetic acid results in decreased expression of CES3 mRNA
CTD
PMID:21046364
NCBI chr19:32,992,386...33,000,562
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Col1a2
collagen type I alpha 2 chain
decreases expression
EXP
dibromoacetic acid results in decreased expression of COL1A2 mRNA
CTD
PMID:21046364
NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867
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Cyp17a1
cytochrome P450, family 17, subfamily a, polypeptide 1
decreases expression
EXP
dibromoacetic acid results in decreased expression of CYP17A1 mRNA
CTD
PMID:21046364
NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573
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Cyp1b1
cytochrome P450, family 1, subfamily b, polypeptide 1
decreases expression
EXP
dibromoacetic acid results in decreased expression of CYP1B1 mRNA
CTD
PMID:21046364
NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
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Dpt
dermatopontin
decreases expression
EXP
dibromoacetic acid results in decreased expression of DPT mRNA
CTD
PMID:21046364
NCBI chr13:77,123,224...77,151,646
Ensembl chr13:77,123,115...77,151,639
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Elk1
ETS transcription factor ELK1
increases expression
ISO
dibromoacetic acid results in increased expression of ELK1 mRNA
CTD
PMID:29155130
NCBI chr X:1,138,826...1,155,713
Ensembl chr X:1,139,756...1,155,713
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Esr1
estrogen receptor 1
multiple interactions
EXP
dibromoacetic acid inhibits the reaction [Estradiol binds to ESR1 protein]
CTD
PMID:10580743
NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
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Fads1
fatty acid desaturase 1
decreases expression
EXP
dibromoacetic acid results in decreased expression of FADS1 mRNA
CTD
PMID:21046364
NCBI chr 1:206,827,724...206,842,734
Ensembl chr 1:206,827,765...206,842,734
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Fas
Fas cell surface death receptor
increases expression
ISO
dibromoacetic acid results in increased expression of FAS mRNA; dibromoacetic acid results in increased expression of FAS protein
CTD
PMID:18628252
NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
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Faslg
Fas ligand
increases expression
ISO
dibromoacetic acid results in increased expression of FASL protein
CTD
PMID:18628252
NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
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Hao2
hydroxyacid oxidase 2
decreases expression
EXP
dibromoacetic acid results in decreased expression of HAO2 mRNA
CTD
PMID:21046364
NCBI chr 2:186,200,137...186,232,997
Ensembl chr 2:186,200,504...186,224,425
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Hba-a2
hemoglobin alpha, adult chain 2
decreases expression
EXP
dibromoacetic acid results in decreased expression of HBA-A2 mRNA
CTD
PMID:21046364
NCBI chr10:15,323,830...15,324,677
Ensembl chr10:15,307,815...15,338,392
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Hbb
hemoglobin subunit beta
decreases expression
EXP
dibromoacetic acid results in decreased expression of HBB mRNA
CTD
PMID:21046364
NCBI chr 1:158,250,421...158,251,832
Ensembl chr 1:158,120,200...158,252,012
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Igfbp7
insulin-like growth factor binding protein 7
decreases expression
EXP
dibromoacetic acid results in decreased expression of IGFBP7 mRNA
CTD
PMID:21046364
NCBI chr14:30,737,414...30,797,317
Ensembl chr14:30,737,164...30,797,314
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Insl3
insulin-like 3
decreases expression
EXP
dibromoacetic acid results in decreased expression of INSL3 mRNA
CTD
PMID:21046364
NCBI chr16:18,398,682...18,400,566
Ensembl chr16:18,384,829...18,400,560
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Myc
MYC proto-oncogene, bHLH transcription factor
decreases methylation
ISO
dibromoacetic acid results in decreased methylation of MYC promoter
CTD
PMID:16014735
NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
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Traf2
Tnf receptor-associated factor 2
increases expression
ISO
dibromoacetic acid results in increased expression of TRAF2 mRNA
CTD
PMID:18628252
NCBI chr 3:8,341,950...8,366,609
Ensembl chr 3:8,341,951...8,366,538
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