Gene: Iapp (islet amyloid polypeptide) Rattus norvegicus
Symbol: Iapp
Name: islet amyloid polypeptide
Description: ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN eating behavior; negative regulation of bone resorption (ortholog); negative regulation of cell differentiation (ortholog); PARTICIPATES IN maturity onset diabetes of the young pathway; ASSOCIATED WITH Diabetes Mellitus, Type 1 (ortholog); Diabetes Mellitus, Type 2 (ortholog); FOUND IN extracellular space (ortholog); neuronal cell body (ortholog); INTERACTS WITH 2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile; aldehydo-D-glucose; ammonium chloride
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: amylin; DAP; diabetes-associated peptide
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.04176,509,863 - 176,517,903 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.04240,723,950 - 240,731,446 (+)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.44179,855,956 - 179,860,871 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14180,100,696 - 180,106,512 (+)NCBI
Celera4163,770,383 - 163,775,298 (+)NCBI
Cytogenetic Map4q44NCBImapview
RH 3.4 Map41043.4RGD
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Iapp
Entrez Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 2854
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2016-08-09
Status: ACTIVE