| 1310969 | Ino80 | INO80 complex ATPase subunit | ENCODES a protein that exhibits alpha-tubulin binding (ortholog); ATP-dependent activity, acting on DNA (ortholog); DNA binding (ortholog); INVOLVED IN cellular response to ionizing radiation (ortholog); cellular response to UV (ortholog); chromatin remodeling (ortholog); PARTICIPATES IN INO80 ='font-weight:700;'>INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH epilepsy (ortholog); intellectual disability (ortholog); microcephaly (ortholog); FOUND IN cytosol (ortholog); Ino80 complex (ortholog); nuclear body (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol; amphetamine | 3 | 126822280 | 126919532 | Rat | 156 | symbol , old_gene_name , PhenoGen , name , description | gene, protein-coding, INFERRED [RefSeq] |
| 1322172 | Ino80 | INO80 complex subunit | Predicted to enable several functions, including ATP hydrolysis activity; alpha-tubulin binding activity; and histone binding activity. Involved in positive regulation of DNA metabolic process; regulation of embryonic development; and telomere maintenance. Predicted to be located in cytosol and nucl ear body. Predicted to be part of Ino80 complex. Is expressed in several structures, including ectoderm; genitourinary system; liver; muscle tissue; and primitive endoderm. Orthologous to human INO80 (INO80 complex ATPase subunit). [provided by Alliance of Genome Resources, Jul 2025] | 2 | 119203523 | 119308168 | Mouse | 195 | symbol , old_gene_name , PhenoGen , name , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1607029 | INO80 | INO80 complex ATPase subunit | This gene encodes a subunit of the chromatin remodeling complex, which is classified into subfamilies depending on sequence features apart from the conserved ATPase domain. This protein is the catalytic ATPase subunit of the INO80 chromatin remodeling complex, w hich is characterized by a DNA-binding domain. This protein is proposed to bind DNA and be recruited by the YY1 transcription factor to activate certain genes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013] | 15 | 40978880 | 41116280 | Human | 141 | symbol , old_gene_name , COSMIC , name , description , Human Proteome Map , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 8745311 | Ino80 | INO80 complex ATPase subunit | ENCODES a protein that exhibits alpha-tubulin binding (ortholog); ATP-dependent activity, acting on DNA (ortholog); DNA binding (ortholog); INVOLVED IN cellular response to ionizing radiation (ortholog); cellular response to UV (ortholog); chromatin remodeling (ortholog); PARTICIPATES IN INO80 ='font-weight:700;'>INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH epilepsy (ortholog); intellectual disability (ortholog); microcephaly (ortholog); FOUND IN cytosol (ortholog); Ino80 complex (ortholog); nuclear body (ortholog) | NW_004955416 | 7870521 | 8020862 | Chinchilla | 40 | symbol , old_gene_name , name , description | gene, protein-coding, MODEL [RefSeq] |
| 11927115 | INO80 | INO80 complex ATPase subunit | ENCODES a protein that exhibits actin binding (inferred); alpha-tubulin binding (inferred); ATP binding (inferred); INVOLVED IN cell division (inferred); cellular response to ionizing radiation (inferred); cellular response to UV (inferred); PARTICIPATES IN INO80 > family mediated chromatin remodeling pathway; ASSOCIATED WITH epilepsy (ortholog); intellectual disability (ortholog); microcephaly (ortholog); FOUND IN chromosome (inferred); cytosol (inferred); Ino80 complex (inferred) | 15 | 19920980 | 20058117 | Bonobo | 76 | symbol , old_gene_name , name , description | gene, protein-coding, MODEL [RefSeq] |
| 12079506 | INO80 | INO80 complex ATPase subunit | ENCODES a protein that exhibits actin binding (inferred); alpha-tubulin binding (inferred); ATP binding (inferred); INVOLVED IN cell division (inferred); cellular response to ionizing radiation (inferred); cellular response to UV (inferred); PARTICIPATES IN INO80 > family mediated chromatin remodeling pathway; ASSOCIATED WITH epilepsy (ortholog); intellectual disability (ortholog); microcephaly (ortholog); FOUND IN chromosome (inferred); cytosol (inferred); Ino80 complex (inferred) | 30 | 8100536 | 8229868 | Dog | 75 | symbol , old_gene_name , name , description | gene, protein-coding, MODEL [RefSeq] |
| 12520320 | Ino80 | INO80 complex ATPase subunit | ENCODES a protein that exhibits actin binding (inferred); alpha-tubulin binding (inferred); ATP binding (inferred); INVOLVED IN cell division (inferred); cellular response to ionizing radiation (inferred); cellular response to UV (inferred); PARTICIPATES IN INO80 > family mediated chromatin remodeling pathway; ASSOCIATED WITH epilepsy (ortholog); intellectual disability (ortholog); microcephaly (ortholog); FOUND IN chromosome (inferred); cytosol (inferred); Ino80 complex (inferred) | NW_004936471 | 4374802 | 4478894 | Squirrel | 75 | symbol , old_gene_name , name , description | gene, protein-coding, MODEL [RefSeq] |
| 14249998 | INO80 | INO80 complex ATPase subunit | ENCODES a protein that exhibits actin binding (inferred); alpha-tubulin binding (inferred); ATP binding (inferred); INVOLVED IN cell division (inferred); cellular response to ionizing radiation (inferred); cellular response to UV (inferred); PARTICIPATES IN INO80 > family mediated chromatin remodeling pathway; ASSOCIATED WITH epilepsy (ortholog); intellectual disability (ortholog); microcephaly (ortholog); FOUND IN chromosome (inferred); cytosol (inferred); Ino80 complex (inferred) | | | | Pig | 76 | symbol , old_gene_name , name , description | gene, protein-coding, MODEL [RefSeq] |
| 14377604 | INO80 | | | | | | Yeast | | symbol | gene, null |
| 14377605 | Ino80 | | | | | | Fly | | symbol | gene, null |
| 18693133 | INO80 | INO80 complex ATPase subunit | ENCODES a protein that exhibits actin binding (inferred); alpha-tubulin binding (inferred); ATP binding (inferred); INVOLVED IN cell division (inferred); cellular response to ionizing radiation (inferred); cellular response to UV (inferred); PARTICIPATES IN INO80 > family mediated chromatin remodeling pathway; ASSOCIATED WITH epilepsy (ortholog); intellectual disability (ortholog); microcephaly (ortholog); FOUND IN chromosome (inferred); cytosol (inferred); Ino80 complex (inferred) | | | | Green Monkey | 75 | symbol , old_gene_name , name , description | gene, protein-coding, MODEL [RefSeq] |
| 18933459 | Ino80 | INO80 complex ATPase subunit | ENCODES a protein that exhibits alpha-tubulin binding (ortholog); ATP-dependent activity, acting on DNA (ortholog); INVOLVED IN cellular response to ionizing radiation (ortholog); cellular response to UV (ortholog); double-strand break repair (ortholog); PARTICIPATES IN INO80 '>INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH epilepsy (ortholog); intellectual disability (ortholog); microcephaly (ortholog); FOUND IN cytosol (ortholog); nuclear body (ortholog); nucleoplasm (ortholog) | | | | Naked Mole-Rat | 71 | symbol , old_gene_name , name , description | gene, protein-coding, MODEL [RefSeq] |
| 284532106 | ino80 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 598150493 | Ino80 | | | | | | Fly | | symbol | gene, null |
| 598150793 | Ino80 | | | | | | Fly | | symbol | gene, null |
| 598150829 | Ino80 | | | | | | Fly | | symbol | gene, null |
| 598153847 | Ino80 | | | | | | Fly | | symbol | gene, null |
| 598153903 | Ino80 | | | | | | Fly | | symbol | gene, null |
| 625985988 | Ino80 | INO80 complex ATPase subunit | ENCODES a protein that exhibits alpha-tubulin binding (ortholog); ATP-dependent activity, acting on DNA (ortholog); DNA binding (ortholog); INVOLVED IN cellular response to ionizing radiation (ortholog); cellular response to UV (ortholog); chromatin remodeling (ortholog); PARTICIPATES IN INO80 ='font-weight:700;'>INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH epilepsy (ortholog); intellectual disability (ortholog); microcephaly (ortholog); FOUND IN cytosol (ortholog); Ino80 complex (ortholog); nuclear body (ortholog) | | | | Black Rat | 40 | symbol , old_gene_name , name , description | gene, protein-coding, MODEL [RefSeq] |
| 288071166 | ino80.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 405857010 | ino80.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 405857980 | ino80.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 405861675 | ino80.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 405862015 | ino80.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 626187275 | ino80.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 12791241 | INO80-AS1 | INO80 antisense RNA 1 | INTERACTS WITH lipopolysaccharide; S-(1,2-dichlorovinyl)-L-cysteine; sodium arsenite | 15 | 41016800 | 41027891 | Human | 5 | symbol , COSMIC , name , Human Proteome Map | gene, ncrna, VALIDATED [RefSeq] |
| 1347975 | INO80B | INO80 complex subunit B | This gene encodes a subunit of an ATP-dependent chromatin remodeling complex, INO80, which plays a role in DNA and nucleosome-activated ATPase activity and ATP-dependent nucleosome sliding. Readthrough transcription of this gene into the neighboring downstream g ene, which encodes WW domain-binding protein 1, generates a non-coding transcript. [provided by RefSeq, Feb 2011] | 2 | 74455087 | 74457944 | Human | 88 | symbol , COSMIC , name , description , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1557374 | Ino80b | INO80 complex subunit B | Predicted to enable zinc ion binding activity. Involved in positive regulation of DNA metabolic process; regulation of embryonic development; and telomere maintenance. Predicted to be located in nuclear body and nucleolus. Predicted to be part of Ino80 complex. Is expressed in Harderian gland; duodenum; metanephros; oviduct; and uterus. Orthologous to human INO80B (INO80 complex subunit B). [provided by Alliance of Genome Resources, Jul 2025] | 6 | 83098746 | 83102100 | Mouse | 93 | symbol , PhenoGen , name , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1562258 | Ino80b | INO80 complex subunit B | INVOLVED IN chromatin remodeling (ortholog); positive regulation of DNA repair (ortholog); positive regulation of DNA-templated transcription (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN Ino80 Ino80 complex (ortholog); nuclear body (ortholog); nucleolus (ortholog); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol | 4 | 117185427 | 117188930 | Rat | 89 | symbol , PhenoGen , name , description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 8936003 | Ino80b | INO80 complex subunit B | INVOLVED IN chromatin remodeling (ortholog); positive regulation of DNA repair (ortholog); positive regulation of DNA-templated transcription (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN Ino80 Ino80 complex (ortholog); nuclear body (ortholog); nucleolus (ortholog) | NW_004955424 | 11324741 | 11327466 | Chinchilla | 20 | symbol , name , description | gene, protein-coding, MODEL [RefSeq] |
| 11945105 | INO80B | INO80 complex subunit B | INVOLVED IN positive regulation of DNA repair (ortholog); positive regulation of telomere maintenance in response to DNA damage (ortholog); regulation of DNA repair (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN Ino80 yle='font-weight:700;'>Ino80 complex (inferred); nuclear body (inferred); nucleolus (inferred) | 2A | 74521624 | 74524578 | Bonobo | 23 | symbol , name , description | gene, protein-coding, MODEL [RefSeq] |
| 12339646 | INO80B | INO80 complex subunit B | INVOLVED IN positive regulation of DNA repair (ortholog); positive regulation of telomere maintenance in response to DNA damage (ortholog); regulation of DNA repair (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN Ino80 yle='font-weight:700;'>Ino80 complex (inferred); nuclear body (inferred); nucleolus (inferred) | 17 | 48674004 | 48676869 | Dog | 23 | symbol , name , description | gene, protein-coding, MODEL [RefSeq] |
| 12458486 | Ino80b | INO80 complex subunit B | INVOLVED IN positive regulation of DNA repair (ortholog); positive regulation of telomere maintenance in response to DNA damage (ortholog); regulation of DNA repair (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN Ino80 yle='font-weight:700;'>Ino80 complex (inferred); nuclear body (inferred); nucleolus (inferred) | NW_004936556 | 678073 | 681157 | Squirrel | 23 | symbol , name , description | gene, protein-coding, MODEL [RefSeq] |
| 14143938 | INO80B | INO80 complex subunit B | INVOLVED IN positive regulation of DNA repair (ortholog); positive regulation of telomere maintenance in response to DNA damage (ortholog); regulation of DNA repair (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN Ino80 yle='font-weight:700;'>Ino80 complex (inferred); nuclear body (inferred); nucleolus (inferred) | | | | Pig | 23 | symbol , name , description | gene, protein-coding, MODEL [RefSeq] |
| 18463480 | INO80B | INO80 complex subunit B | INVOLVED IN positive regulation of DNA repair (ortholog); positive regulation of telomere maintenance in response to DNA damage (ortholog); regulation of DNA repair (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN Ino80 yle='font-weight:700;'>Ino80 complex (inferred); nuclear body (inferred); nucleolus (inferred) | | | | Green Monkey | 23 | symbol , name , description | gene, protein-coding, MODEL [RefSeq] |
| 18933154 | Ino80b | INO80 complex subunit B | INVOLVED IN positive regulation of DNA repair (ortholog); positive regulation of DNA-templated transcription (ortholog); positive regulation of telomere maintenance in response to DNA damage (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN nuclear body (ortholog); nucleolus (ortholog); nucleoplasm (ortholog) | | | | Naked Mole-Rat | 21 | symbol , name , description | gene, protein-coding, MODEL [RefSeq] |
| 626137598 | Ino80b | INO80 complex subunit B | INVOLVED IN chromatin remodeling (ortholog); positive regulation of DNA repair (ortholog); positive regulation of DNA-templated transcription (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN Ino80 Ino80 complex (ortholog); nuclear body (ortholog); nucleolus (ortholog) | | | | Black Rat | 20 | symbol , name , description | gene, protein-coding, MODEL [RefSeq] |
| 1310199 | Ino80c | INO80 complex subunit C | INVOLVED IN chromatin remodeling (ortholog); positive regulation of DNA repair (ortholog); positive regulation of DNA-templated transcription (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN fibrillar center (ortholog); ... (more) pan style='font-weight:700;'>Ino80 complex (ortholog); MLL1 complex (ortholog); INTERACTS WITH bisphenol A; caffeine; flutamide | 18 | 15653508 | 15752455 | Rat | 96 | symbol , PhenoGen , name , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1320959 | INO80C | INO80 complex subunit C | Involved in several processes, including chromatin remodeling; regulation of chromosome organization; and regulation of nucleobase-containing compound metabolic process. Located in cytosol; fibrillar center; and nucleoplasm. Part of Ino80 complex and MLL1 comple x. [provided by Alliance of Genome Resources, Jul 2025] | 18 | 35468333 | 35497960 | Human | 81 | symbol , COSMIC , name , description , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1320960 | Ino80c | INO80 complex subunit C | Involved in positive regulation of DNA metabolic process; regulation of embryonic development; and telomere maintenance. Predicted to be part of Ino80 complex and MLL1 complex. Orthologous to human INO80C (INO80 weight:700;'>INO80 complex subunit C). [provided by Alliance of Genome Resources, Apr 2025] | 18 | 24237818 | 24254876 | Mouse | 110 | symbol , PhenoGen , name , description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 8972191 | Ino80c | INO80 complex subunit C | INVOLVED IN chromatin remodeling (ortholog); positive regulation of DNA repair (ortholog); positive regulation of DNA-templated transcription (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN fibrillar center (ortholog); ... (more) pan style='font-weight:700;'>Ino80 complex (ortholog); MLL1 complex (ortholog) | NW_004955402 | 22189943 | 22210315 | Chinchilla | 18 | symbol , name , description | gene, protein-coding, MODEL [RefSeq] |
| 11803027 | INO80C | INO80 complex subunit C | INVOLVED IN chromatin remodeling (inferred); DNA-templated transcription (inferred); positive regulation of DNA repair (inferred); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN fibrillar center (inferred); Ino80 700;'>Ino80 complex (inferred); MLL1 complex (inferred) | 18 | 28686112 | 28715946 | Bonobo | 24 | symbol , name , description | gene, protein-coding, MODEL [RefSeq] |
| 12402575 | INO80C | INO80 complex subunit C | INVOLVED IN chromatin remodeling (inferred); DNA-templated transcription (inferred); positive regulation of DNA repair (inferred); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN fibrillar center (inferred); Ino80 700;'>Ino80 complex (inferred); MLL1 complex (inferred); INTERACTS WITH bisphenol A | 7 | 54569954 | 54586902 | Dog | 25 | symbol , name , description | gene, protein-coding, MODEL [RefSeq] |
| 12539671 | Ino80c | INO80 complex subunit C | INVOLVED IN chromatin remodeling (inferred); DNA-templated transcription (inferred); positive regulation of DNA repair (inferred); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN fibrillar center (inferred); Ino80 700;'>Ino80 complex (inferred); MLL1 complex (inferred) | NW_004936517 | 9632870 | 9649525 | Squirrel | 24 | symbol , old_gene_name , name , description | gene, protein-coding, MODEL [RefSeq] |
| 14287931 | INO80C | INO80 complex subunit C | INVOLVED IN chromatin remodeling (inferred); DNA-templated transcription (inferred); positive regulation of DNA repair (inferred); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN fibrillar center (inferred); Ino80 700;'>Ino80 complex (inferred); MLL1 complex (inferred) | | | | Pig | 24 | symbol , name , description | gene, protein-coding, MODEL [RefSeq] |
| 18359711 | INO80C | INO80 complex subunit C | INVOLVED IN chromatin remodeling (inferred); DNA-templated transcription (inferred); positive regulation of DNA repair (inferred); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN fibrillar center (inferred); Ino80 700;'>Ino80 complex (inferred); MLL1 complex (inferred) | | | | Green Monkey | 24 | symbol , name , description | gene, protein-coding, MODEL [RefSeq] |
| 18910402 | Ino80c | INO80 complex subunit C | INVOLVED IN positive regulation of DNA repair (ortholog); positive regulation of DNA-templated transcription (ortholog); positive regulation of telomere maintenance in response to DNA damage (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN fibrillar center (ortholog); MLL1 complex (ortholog); nucleoplasm (ortholog) | | | | Naked Mole-Rat | 22 | symbol , name , description | gene, protein-coding, MODEL [RefSeq] |
| 625894440 | Ino80c | INO80 complex subunit C | INVOLVED IN chromatin remodeling (ortholog); positive regulation of DNA repair (ortholog); positive regulation of DNA-templated transcription (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN fibrillar center (ortholog); ... (more) pan style='font-weight:700;'>Ino80 complex (ortholog); MLL1 complex (ortholog) | | | | Black Rat | 18 | symbol , name , description | gene, protein-coding, MODEL [RefSeq] |
| 1304808 | Ino80d | INO80 complex subunit D | INVOLVED IN chromatin remodeling (ortholog); positive regulation of DNA repair (ortholog); positive regulation of DNA-templated transcription (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN nucleus (inferred); INTERACTS W ITH 17alpha-ethynylestradiol; 2,3,7,8-Tetrachlorodibenzofuran; amphetamine | 9 | 71940941 | 72007879 | Rat | 90 | symbol , PhenoGen , name , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1606537 | INO80D | INO80 complex subunit D | Involved in several processes, including chromatin remodeling; regulation of chromosome organization; and regulation of nucleobase-containing compound metabolic process. Part of Ino80 complex. [provided by Alliance of Genome Resources, Jul 2025] | 2 | 205993721 | 206086174 | Human | 83 | symbol , COSMIC , name , description , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1616557 | Ino80d | INO80 complex subunit D | Involved in positive regulation of DNA metabolic process; regulation of embryonic development; and telomere maintenance. Predicted to be part of Ino80 complex. Predicted to be active in nucleus. Is expressed in several structures, including endocrine gland; gall bladder; genitourinary system; nervous system; and skeletal muscle tissue. Orthologous to human INO80D (INO80 complex subunit D). [provided by Alliance of Genome Resources, Jul 2025] | 1 | 63086960 | 63153693 | Mouse | 105 | symbol , PhenoGen , name , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8724047 | Ino80d | INO80 complex subunit D | INVOLVED IN chromatin remodeling (ortholog); positive regulation of DNA repair (ortholog); positive regulation of DNA-templated transcription (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway | NW_004955457 | 8913625 | 8983859 | Chinchilla | 12 | symbol , name , description | gene, protein-coding, MODEL [RefSeq] |
| 11926725 | INO80D | INO80 complex subunit D | INVOLVED IN chromatin remodeling (inferred); positive regulation of DNA repair (inferred); positive regulation of DNA-templated transcription (inferred); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN nucleus (inferred) | 2B | 93233672 | 93325871 | Bonobo | 14 | symbol , name , description | gene, protein-coding, MODEL [RefSeq] |
| 12148691 | INO80D | INO80 complex subunit D | INVOLVED IN chromatin remodeling (inferred); positive regulation of DNA repair (inferred); positive regulation of DNA-templated transcription (inferred); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN nucleus (inferred) | 37 | 14581531 | 14647930 | Dog | 14 | symbol , name , description | gene, protein-coding, MODEL [RefSeq] |
| 12711808 | Ino80d | INO80 complex subunit D | INVOLVED IN chromatin remodeling (inferred); positive regulation of DNA repair (inferred); positive regulation of DNA-templated transcription (inferred); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN nucleus (inferred) | NW_004936631 | 2405056 | 2474798 | Squirrel | 14 | symbol , old_gene_name , name , description | gene, protein-coding, MODEL [RefSeq] |
| 13966895 | INO80D | INO80 complex subunit D | INVOLVED IN chromatin remodeling (inferred); positive regulation of DNA repair (inferred); positive regulation of DNA-templated transcription (inferred); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN nucleus (inferred) | | | | Pig | 14 | symbol , name , description | gene, protein-coding, MODEL [RefSeq] |
| 18787991 | INO80D | INO80 complex subunit D | INVOLVED IN chromatin remodeling (inferred); positive regulation of DNA repair (inferred); positive regulation of DNA-templated transcription (inferred); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN nucleus (inferred) | | | | Green Monkey | 14 | symbol , name , description | gene, protein-coding, MODEL [RefSeq] |
| 18923470 | Ino80d | INO80 complex subunit D | INVOLVED IN chromatin remodeling (ortholog); positive regulation of DNA repair (ortholog); positive regulation of DNA-templated transcription (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN nucleus (inferred) | | | | Naked Mole-Rat | 14 | symbol , name , description | gene, protein-coding, MODEL [RefSeq] |
| 625924716 | Ino80d | INO80 complex subunit D | INVOLVED IN chromatin remodeling (ortholog); positive regulation of DNA repair (ortholog); positive regulation of DNA-templated transcription (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway | | | | Black Rat | 12 | symbol , name , description | gene, protein-coding, MODEL [RefSeq] |
| 1359572 | Ino80e | INO80 complex subunit E | INVOLVED IN chromatin remodeling (ortholog); positive regulation of DNA-templated transcription (ortholog); regulation of cell cycle (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH spondylocostal dysostosis 5 (orth olog); FOUND IN Ino80 complex (ortholog); nucleolus (ortholog); nucleoplasm (ortholog); INTERACTS WITH acrylamide; fenvalerate; lead diacetate | 1 | 190891315 | 190902902 | Rat | 72 | symbol , PhenoGen , name , description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1605827 | INO80E | INO80 complex subunit E | Involved in several processes, including chromatin remodeling; regulation of chromosome organization; and regulation of nucleobase-containing compound metabolic process. Located in nucleolus and nucleoplasm. Part of Ino80 complex. [provided by Alliance of Genome Resources, Jul 2025] | 16 | 29996241 | 30005791 | Human | 67 | symbol , COSMIC , name , description , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1614915 | Ino80e | INO80 complex subunit E | Predicted to be involved in several processes, including chromatin remodeling; regulation of chromosome organization; and regulation of nucleobase-containing compound metabolic process. Predicted to be located in nucleolus and nucleoplasm. Predicted to be part of Ino80 complex. Is expressed in cerebral cortex ventricular layer and cortical plate. Orthologous to human INO80E (INO80 complex subunit E). [provided by Alliance of Genome Resources, Jul 2025] | 7 | 126450756 | 126461544 | Mouse | 73 | symbol , PhenoGen , name , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8736631 | Ino80e | INO80 complex subunit E | INVOLVED IN chromatin remodeling (ortholog); positive regulation of DNA-templated transcription (ortholog); regulation of cell cycle (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH spondylocostal dysostosis 5 (orth olog); FOUND IN Ino80 complex (ortholog); nucleolus (ortholog); nucleoplasm (ortholog) | NW_004955493 | 6953945 | 6963910 | Chinchilla | 17 | symbol , name , description | gene, protein-coding, MODEL [RefSeq] |
| 11840977 | INO80E | INO80 complex subunit E | INVOLVED IN chromatin remodeling (inferred); positive regulation of DNA-templated transcription (inferred); regulation of cell cycle (inferred); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH spondylocostal dysostosis 5 (orth olog); FOUND IN Ino80 complex (inferred); nucleolus (inferred); nucleoplasm (inferred) | | | | Bonobo | 21 | symbol , name , description | gene, protein-coding, MODEL [RefSeq] |
| 12234447 | INO80E | INO80 complex subunit E | INVOLVED IN chromatin remodeling (inferred); positive regulation of DNA-templated transcription (inferred); regulation of cell cycle (inferred); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH spondylocostal dysostosis 5 (orth olog); FOUND IN Ino80 complex (inferred); nucleolus (inferred); nucleoplasm (inferred) | 6 | 18033366 | 18041604 | Dog | 21 | symbol , name , description | gene, protein-coding, MODEL [RefSeq] |
| 12663996 | Ino80e | INO80 complex subunit E | INVOLVED IN chromatin remodeling (inferred); positive regulation of DNA-templated transcription (inferred); regulation of cell cycle (inferred); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH spondylocostal dysostosis 5 (orth olog); FOUND IN Ino80 complex (inferred); nucleolus (inferred); nucleoplasm (inferred) | NW_004936501 | 12463592 | 12472271 | Squirrel | 21 | symbol , old_gene_name , name , description | gene, protein-coding, MODEL [RefSeq] |
| 13924504 | INO80E | INO80 complex subunit E | INVOLVED IN chromatin remodeling (inferred); positive regulation of DNA-templated transcription (inferred); regulation of cell cycle (inferred); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH spondylocostal dysostosis 5 (orth olog); FOUND IN Ino80 complex (inferred); nucleolus (inferred); nucleoplasm (inferred) | | | | Pig | 21 | symbol , name , description | gene, protein-coding, MODEL [RefSeq] |
| 18611023 | INO80E | INO80 complex subunit E | INVOLVED IN chromatin remodeling (inferred); positive regulation of DNA-templated transcription (inferred); regulation of cell cycle (inferred); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH spondylocostal dysostosis 5 (orth olog); FOUND IN Ino80 complex (inferred); nucleolus (inferred); nucleoplasm (inferred) | | | | Green Monkey | 21 | symbol , name , description | gene, protein-coding, MODEL [RefSeq] |
| 18932561 | Ino80e | INO80 complex subunit E | INVOLVED IN chromatin remodeling (inferred); positive regulation of DNA-templated transcription (inferred); regulation of cell cycle (inferred); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH spondylocostal dysostosis 5 (orth olog); FOUND IN Ino80 complex (inferred); nucleolus (inferred); nucleoplasm (inferred) | | | | Naked Mole-Rat | 21 | symbol , name , description | gene, protein-coding, MODEL [RefSeq] |
| 626037562 | Ino80e | INO80 complex subunit E | INVOLVED IN chromatin remodeling (ortholog); positive regulation of DNA-templated transcription (ortholog); regulation of cell cycle (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN Ino80 an> complex (ortholog); nucleolus (ortholog); nucleoplasm (ortholog) | | | | Black Rat | 16 | symbol , name , description | gene, protein-coding, MODEL [RefSeq] |
| 10087470 | LOC106147472 | putative DNA helicase ino80 | | NW_004955566 | 1378986 | 1382229 | Chinchilla | | name | gene, protein-coding, MODEL [RefSeq] |
| 10171670 | LOC106146382 | INO80 complex subunit B-like | | NW_004955476 | 6608079 | 6610286 | Chinchilla | | name | gene, protein-coding, MODEL [RefSeq] |
| 12939850 | LOC110598894 | INO80 complex subunit E-like | | NW_004936596 | 5482068 | 5483191 | Squirrel | | old_gene_name , name | gene, pseudo, MODEL [RefSeq] |
| 18930877 | LOC101718130 | INO80 complex subunit B pseudogene | | | | | Naked Mole-Rat | | name | gene, pseudo, MODEL [RefSeq] |
| 18762597 | LOC103243228 | INO80 complex subunit C pseudogene | | | | | Green Monkey | | old_gene_name , name | gene, pseudo, MODEL [RefSeq] |
| 18471982 | LOC103244012 | INO80 complex subunit C pseudogene | | | | | Green Monkey | | old_gene_name , name | gene, pseudo, MODEL [RefSeq] |
| 16562225 | AC020661.2 | novel transcript, antisense to INO80 | | | | | Human | | name | gene, lncrna |
| 3962436 | Ino80dos | INO80 complex subunit D, opposite strand | Orthologous to human INO80D-AS1 (INO80D antisense RNA 1). [provided by Alliance of Genome Resources, Jul 2025] | 1 | 63153630 | 63197454 | Mouse | 3 | symbol , PhenoGen , name , description | gene, ncrna, VALIDATED [RefSeq] |
| 16569575 | AC020661.4 | novel transcript, sense intronic to INO80 | | | | | Human | | name | gene, lncrna |
| 1603412 | ACTL6A | actin like 6A | This gene encodes a family member of actin-related proteins (ARPs), which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a 53 kDa subunit protein of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. Together with beta-actin, it is required for maximal ATPase activity of BRG1, and for the association of the BAF complex with chromatin/matrix. Three transcript variants that encode two different protein isoforms have been described. [provided by RefSeq, Jul 2008] | 3 | 179562926 | 179588407 | Human | 183 | old_gene_name , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1317453 | ACTR5 | actin related protein 5 | Involved in several processes, including DNA repair; chromatin remodeling; and regulation of nucleobase-containing compound metabolic process. Located in cytoplasm and nucleus. Part of Ino80 complex. [provided by Alliance of Genome Resources, Jul 2025] | 20 | 38748460 | 38772520 | Human | 67 | old_gene_name , description , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1323563 | ACTR8 | actin related protein 8 | Predicted to enable ATP binding activity. Involved in several processes, including chromatin remodeling; regulation of chromosome organization; and regulation of nucleobase-containing compound metabolic process. Located in centrosome and nucleoplasm. Part of Ino80 n> complex. [provided by Alliance of Genome Resources, Jul 2025] | 3 | 53858992 | 53882152 | Human | 78 | old_gene_name , description , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1323153 | MCRS1 | microspherule protein 1 | Enables RNA binding activity and telomerase inhibitor activity. Involved in several processes, including chromatin remodeling; positive regulation of protein localization to nucleolus; and regulation of nucleobase-containing compound metabolic process. Located in cytoplasm; nuclear body; and nucleol us. Part of Ino80 complex; MLL1 complex; and NSL complex. [provided by Alliance of Genome Resources, Apr 2025] | 12 | 49558299 | 49568142 | Human | 131 | old_gene_name , description , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1321531 | NFRKB | nuclear factor related to kappaB binding protein | Enables protease binding activity. Involved in several processes, including chromatin remodeling; regulation of chromosome organization; and regulation of nucleobase-containing compound metabolic process. Located in Ino80 complex and nucleoplasm. [provided by Al liance of Genome Resources, Jul 2025] | 11 | 129863636 | 129895578 | Human | 96 | old_gene_name , description , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 68537 | RUVBL1 | RuvB like AAA ATPase 1 | This gene encodes a protein that has both DNA-dependent ATPase and DNA helicase activities and belongs to the ATPases associated with diverse cellular activities (AAA+) protein family. The encoded protein associates with several multisubunit transcriptional complexes and with protein complexes invol ved in both ATP-dependent remodeling and histone modification. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016] | 3 | 128064785 | 128153914 | Human | 216 | old_gene_name , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1315165 | RUVBL2 | RuvB like AAA ATPase 2 | This gene encodes the second human homologue of the bacterial RuvB gene. Bacterial RuvB protein is a DNA helicase essential for homologous recombination and DNA double-strand break repair. Functional analysis showed that this gene product has both ATPase and DNA helicase activities. This gene is phy sically linked to the CGB/LHB gene cluster on chromosome 19q13.3, and is very close (55 nt) to the LHB gene, in the opposite orientation. [provided by RefSeq, Jul 2008] | 19 | 48993448 | 49015995 | Human | 210 | old_gene_name , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 733579 | TFPT | TCF3 fusion partner | Predicted to enable DNA binding activity. Involved in several processes, including apoptotic signaling pathway; chromatin remodeling; and regulation of nucleobase-containing compound metabolic process. Located in nucleoplasm. Part of Ino80 complex. [provided by Alliance of Genome Resources, Apr 2025] | 19 | 54107020 | 54115657 | Human | 98 | old_gene_name , description , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1313432 | UCHL5 | ubiquitin C-terminal hydrolase L5 | Enables cysteine-type deubiquitinase activity; endopeptidase inhibitor activity; and proteasome binding activity. Involved in several processes, including positive regulation of smoothened signaling pathway; protein deubiquitination; and regulation of primary metabolic process. Located in cytosol an d nuclear lumen. [provided by Alliance of Genome Resources, Jul 2025] | 1 | 193012254 | 193060076 | Human | 154 | old_gene_name , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 736235 | YY1 | YY1 transcription factor | YY1 is a ubiquitously distributed transcription factor belonging to the GLI-Kruppel class of zinc finger proteins. The protein is involved in repressing and activating a diverse number of promoters. YY1 may direct histone deacetylases and histone acetyltransferases to a promoter in order to activat e or repress the promoter, thus implicating histone modification in the function of YY1. [provided by RefSeq, Jul 2008] | 14 | 100239144 | 100282788 | Human | 436 | old_gene_name , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 38641137 | LOC105376713 | uncharacterized LOC105376713 | | 15 | 40999274 | 41004858 | Human | | old_gene_name | gene, ncrna, MODEL [RefSeq] |
| 155241556 | ino80b | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 288057118 | ino80c | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 284781190 | ino80d | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 155241563 | ino80e | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 155240637 | ino80b.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 285311568 | ino80c.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 283978813 | ino80d.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 284781540 | ino80d.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 155245209 | ino80e.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155239933 | ino80e.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 16553940 | INO80D-AS1 | INO80D antisense RNA 1 | | | | | Human | | symbol , COSMIC , name , Human Proteome Map | gene, lncrna |
| 149736014 | INO80D-AS1 | INO80D antisense RNA 1 | INTERACTS WITH bisphenol A (ortholog); bisphenol F (ortholog); triptonide (ortholog) | 2 | 206084655 | 206087504 | Human | 3 | symbol , GTEx , old_gene_name , COSMIC , name , Human Proteome Map , old_gene_symbol | gene, ncrna, VALIDATED [RefSeq] |
| 7383666 | INO80B-WBP1 | INO80B-WBP1 readthrough (NMD candidate) | This locus represents naturally occurring read-through transcription between the neighboring INO80B (INO80 complex subunit B) and WBP1 (WW domain-binding protein 1) genes on chromosome 2. The read-through transcript is a can didate for nonsense-mediated mRNA decay (NMD), and is unlikely to produce a protein product. [provided by RefSeq, Feb 2011] | 2 | 74455023 | 74460891 | Human | 5 | symbol , COSMIC , name , description , Human Proteome Map | gene, ncrna, VALIDATED [RefSeq] |
| 1307747 | Actl6a | actin-like 6A | ENCODES a protein that exhibits chromatin binding (ortholog); INVOLVED IN spinal cord development; blastocyst formation (ortholog); chromatin remodeling (ortholog); PARTICIPATES IN altered SWI/SNF family mediated chromatin remodeling pathway; INO80 family mediat ed chromatin remodeling pathway; pancreatic cancer pathway; ASSOCIATED WITH Spina Bifida Cystica; atrial heart septal defect (ortholog); cervical dystonia (ortholog); FOUND IN Ino80 complex (ortholog); npBAF complex (ortholog); NuA4 histone acetyltransferase complex (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; amitrole; bis(2-ethylhexyl) phthalate | 2 | 117413206 | 117436758 | Rat | 158 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 8762880 | Actl6a | actin like 6A | ENCODES a protein that exhibits chromatin binding (ortholog); INVOLVED IN blastocyst formation (ortholog); chromatin remodeling (ortholog); nervous system development (ortholog); PARTICIPATES IN altered SWI/SNF family mediated chromatin remodeling pathway; INO80 family mediated chromatin remodeling pathway; pancreatic cancer pathway; ASSOCIATED WITH atrial heart septal defect (ortholog); cervical dystonia (ortholog); Developmental Disabilities (ortholog); FOUND IN Ino80 complex (ortholog); npBAF complex (ortholog); NuA4 histone acetyltransferase complex (ortholog) | NW_004955420 | 8745390 | 8764993 | Chinchilla | 46 | description | gene, protein-coding, MODEL [RefSeq] |
| 11944709 | ACTL6A | actin like 6A | ENCODES a protein that exhibits chromatin binding (inferred); INVOLVED IN blastocyst formation (ortholog); chromatin remodeling (ortholog); spinal cord development (ortholog); PARTICIPATES IN altered SWI/SNF family mediated chromatin remodeling pathway; INO80 fa mily mediated chromatin remodeling pathway; pancreatic cancer pathway; ASSOCIATED WITH atrial heart septal defect (ortholog); cervical dystonia (ortholog); Developmental Disabilities (ortholog); FOUND IN Ino80 complex (inferred); npBAF complex (inferred); NuA4 histone acetyltransferase complex (inferred) | 3 | 176595149 | 176620556 | Bonobo | 57 | description | gene, protein-coding, MODEL [RefSeq] |
| 12113188 | ACTL6A | actin like 6A | ENCODES a protein that exhibits chromatin binding (inferred); INVOLVED IN blastocyst formation (ortholog); chromatin remodeling (ortholog); spinal cord development (ortholog); PARTICIPATES IN altered SWI/SNF family mediated chromatin remodeling pathway; INO80 fa mily mediated chromatin remodeling pathway; pancreatic cancer pathway; ASSOCIATED WITH atrial heart septal defect (ortholog); cervical dystonia (ortholog); Developmental Disabilities (ortholog); FOUND IN Ino80 complex (inferred); npBAF complex (inferred); NuA4 histone acetyltransferase complex (inferred) | 34 | 12922506 | 12988334 | Dog | 66 | description | gene, protein-coding, MODEL [RefSeq] |
| 12629181 | Actl6a | actin like 6A | ENCODES a protein that exhibits chromatin binding (inferred); INVOLVED IN blastocyst formation (ortholog); chromatin remodeling (ortholog); spinal cord development (ortholog); PARTICIPATES IN altered SWI/SNF family mediated chromatin remodeling pathway; INO80 fa mily mediated chromatin remodeling pathway; pancreatic cancer pathway; ASSOCIATED WITH atrial heart septal defect (ortholog); cervical dystonia (ortholog); Developmental Disabilities (ortholog); FOUND IN Ino80 complex (inferred); npBAF complex (inferred); NuA4 histone acetyltransferase complex (inferred) | NW_004936566 | 3577412 | 3587182 | Squirrel | 43 | description | gene, protein-coding, MODEL [RefSeq] |
| 13873059 | ACTL6A | actin like 6A | ENCODES a protein that exhibits chromatin binding (inferred); INVOLVED IN blastocyst formation (ortholog); chromatin remodeling (ortholog); spinal cord development (ortholog); PARTICIPATES IN altered SWI/SNF family mediated chromatin remodeling pathway; INO80 fa mily mediated chromatin remodeling pathway; pancreatic cancer pathway; ASSOCIATED WITH atrial heart septal defect (ortholog); cervical dystonia (ortholog); Developmental Disabilities (ortholog); FOUND IN Ino80 complex (inferred); npBAF complex (inferred); NuA4 histone acetyltransferase complex (inferred) | | | | Pig | 63 | description | gene, protein-coding, MODEL [RefSeq] |
| 18751632 | ACTL6A | actin like 6A | ENCODES a protein that exhibits chromatin binding (inferred); INVOLVED IN blastocyst formation (ortholog); chromatin remodeling (ortholog); spinal cord development (ortholog); PARTICIPATES IN altered SWI/SNF family mediated chromatin remodeling pathway; INO80 fa mily mediated chromatin remodeling pathway; pancreatic cancer pathway; ASSOCIATED WITH atrial heart septal defect (ortholog); cervical dystonia (ortholog); Developmental Disabilities (ortholog); FOUND IN Ino80 complex (inferred); npBAF complex (inferred); NuA4 histone acetyltransferase complex (inferred) | | | | Green Monkey | 57 | description | gene, protein-coding, MODEL [RefSeq] |
| 18936256 | Actl6a | actin like 6A | ENCODES a protein that exhibits chromatin binding (inferred); INVOLVED IN blastocyst formation (ortholog); chromatin remodeling (ortholog); spinal cord development (ortholog); PARTICIPATES IN altered SWI/SNF family mediated chromatin remodeling pathway; INO80 fa mily mediated chromatin remodeling pathway; pancreatic cancer pathway; ASSOCIATED WITH atrial heart septal defect (ortholog); cervical dystonia (ortholog); Developmental Disabilities (ortholog); FOUND IN Ino80 complex (inferred); npBAF complex (inferred); NuA4 histone acetyltransferase complex (inferred) | | | | Naked Mole-Rat | 58 | description | gene, protein-coding, MODEL [RefSeq] |
| 626116373 | Actl6a | actin like 6A | ENCODES a protein that exhibits chromatin binding (ortholog); INVOLVED IN blastocyst formation (ortholog); chromatin remodeling (ortholog); nervous system development (ortholog); PARTICIPATES IN altered SWI/SNF family mediated chromatin remodeling pathway; INO80 family mediated chromatin remodeling pathway; pancreatic cancer pathway; ASSOCIATED WITH atrial heart septal defect (ortholog); cervical dystonia (ortholog); Developmental Disabilities (ortholog); FOUND IN Ino80 complex (ortholog); npBAF complex (ortholog); NuA4 histone acetyltransferase complex (ortholog) | | | | Black Rat | 46 | description | gene, protein-coding, MODEL [RefSeq] |
| 1307958 | Actr5 | actin related protein 5 | INVOLVED IN chromatin remodeling (ortholog); double-strand break repair (ortholog); positive regulation of DNA repair (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN cytoplasm (ortholog); Ino80 o80 complex (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; tetrachloromethane | 3 | 167702299 | 167715736 | Rat | 72 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 8786201 | Actr5 | actin related protein 5 | INVOLVED IN chromatin remodeling (ortholog); double-strand break repair (ortholog); positive regulation of DNA repair (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN cytoplasm (ortholog); Ino80 o80 complex (ortholog); nucleus (ortholog) | NW_004955445 | 17991969 | 18024525 | Chinchilla | 23 | description | gene, protein-coding, MODEL [RefSeq] |
| 11982244 | ACTR5 | actin related protein 5 | INVOLVED IN positive regulation of DNA repair (ortholog); positive regulation of telomere maintenance in response to DNA damage (ortholog); regulation of DNA repair (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN cytoplas m (inferred); Ino80 complex (inferred); nucleus (inferred) | 20 | 35073297 | 35097955 | Bonobo | 32 | description | gene, protein-coding, MODEL [RefSeq] |
| 12091099 | ACTR5 | actin related protein 5 | INVOLVED IN positive regulation of DNA repair (ortholog); positive regulation of telomere maintenance in response to DNA damage (ortholog); regulation of DNA repair (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN cytoplas m (inferred); Ino80 complex (inferred); nucleus (inferred) | 24 | 27154283 | 27190947 | Dog | 37 | description | gene, protein-coding, MODEL [RefSeq] |
| 12601663 | Actr5 | actin related protein 5 | INVOLVED IN positive regulation of DNA repair (ortholog); positive regulation of telomere maintenance in response to DNA damage (ortholog); regulation of DNA repair (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN cytoplas m (inferred); Ino80 complex (inferred); nucleus (inferred) | NW_004936561 | 2676515 | 2701447 | Squirrel | 32 | description | gene, protein-coding, MODEL [RefSeq] |
| 14172315 | ACTR5 | actin related protein 5 | INVOLVED IN positive regulation of DNA repair (ortholog); positive regulation of telomere maintenance in response to DNA damage (ortholog); regulation of DNA repair (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN cytoplas m (inferred); Ino80 complex (inferred); nucleus (inferred) | | | | Pig | 37 | description | gene, protein-coding, MODEL [RefSeq] |
| 18780951 | ACTR5 | actin related protein 5 | INVOLVED IN positive regulation of DNA repair (ortholog); positive regulation of telomere maintenance in response to DNA damage (ortholog); regulation of DNA repair (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN cytoplas m (inferred); Ino80 complex (inferred); nucleus (inferred) | | | | Green Monkey | 32 | description | gene, protein-coding, MODEL [RefSeq] |
| 18908332 | Actr5 | actin related protein 5 | INVOLVED IN chromatin remodeling (ortholog); double-strand break repair (ortholog); positive regulation of DNA repair (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN cytoplasm (ortholog); Ino80 o80 complex (ortholog) | | | | Naked Mole-Rat | 30 | description | gene, protein-coding, MODEL [RefSeq] |
| 626142363 | Actr5 | actin related protein 5 | INVOLVED IN chromatin remodeling (ortholog); double-strand break repair (ortholog); positive regulation of DNA repair (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN cytoplasm (ortholog); Ino80 o80 complex (ortholog); nucleus (ortholog) | | | | Black Rat | 23 | description | gene, protein-coding, MODEL [RefSeq] |
| 1311878 | Actr8 | actin related protein 8 | INVOLVED IN chromatin remodeling (ortholog); positive regulation of DNA repair (ortholog); positive regulation of DNA-templated transcription (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN Ino80 Ino80 complex (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; cadmium dichloride | 16 | 5170649 | 5192883 | Rat | 64 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 8752822 | Actr8 | actin related protein 8 | INVOLVED IN chromatin remodeling (ortholog); positive regulation of DNA repair (ortholog); positive regulation of DNA-templated transcription (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN Ino80 Ino80 complex (ortholog); nucleoplasm (ortholog); nucleus (ortholog) | NW_004955430 | 3851758 | 3867291 | Chinchilla | 17 | description | gene, protein-coding, MODEL [RefSeq] |
| 11691661 | ACTR8 | actin related protein 8 | ENCODES a protein that exhibits ATP binding (inferred); nucleotide binding (inferred); INVOLVED IN cell division (inferred); chromatin remodeling (inferred); DNA damage response (inferred); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUN D IN chromosome (inferred); Ino80 complex (inferred); nucleoplasm (inferred) | 3 | 53802916 | 53820244 | Bonobo | 29 | description | gene, protein-coding, MODEL [RefSeq] |
| 12150482 | ACTR8 | actin related protein 8 | ENCODES a protein that exhibits ATP binding (inferred); nucleotide binding (inferred); INVOLVED IN cell division (inferred); chromatin remodeling (inferred); DNA damage response (inferred); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUN D IN chromosome (inferred); Ino80 complex (inferred); nucleoplasm (inferred) | 20 | 36118471 | 36135064 | Dog | 33 | description | gene, protein-coding, MODEL [RefSeq] |
| 12592305 | Actr8 | actin related protein 8 | ENCODES a protein that exhibits ATP binding (inferred); nucleotide binding (inferred); INVOLVED IN cell division (inferred); chromatin remodeling (inferred); DNA damage response (inferred); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUN D IN chromosome (inferred); Ino80 complex (inferred); nucleoplasm (inferred) | NW_004936473 | 4523865 | 4542476 | Squirrel | 29 | description | gene, protein-coding, MODEL [RefSeq] |
| 14027962 | ACTR8 | actin related protein 8 | ENCODES a protein that exhibits ATP binding (inferred); nucleotide binding (inferred); INVOLVED IN cell division (inferred); chromatin remodeling (inferred); DNA damage response (inferred); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUN D IN chromosome (inferred); Ino80 complex (inferred); membrane (inferred) | | | | Pig | 34 | description | gene, protein-coding, MODEL [RefSeq] |
| 18376527 | ACTR8 | actin related protein 8 | ENCODES a protein that exhibits ATP binding (inferred); nucleotide binding (inferred); INVOLVED IN cell division (inferred); chromatin remodeling (inferred); DNA damage response (inferred); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUN D IN chromosome (inferred); Ino80 complex (inferred); nucleoplasm (inferred) | | | | Green Monkey | 29 | description | gene, protein-coding, MODEL [RefSeq] |
| 18934019 | Actr8 | actin related protein 8 | ENCODES a protein that exhibits ATP binding (inferred); nucleotide binding (inferred); INVOLVED IN cell division (inferred); chromatin remodeling (inferred); DNA damage response (inferred); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUN D IN chromosome (inferred); Ino80 complex (inferred); nucleoplasm (inferred) | | | | Naked Mole-Rat | 29 | description | gene, protein-coding, MODEL [RefSeq] |
| 626040704 | Actr8 | actin related protein 8 | INVOLVED IN chromatin remodeling (ortholog); positive regulation of DNA repair (ortholog); positive regulation of DNA-templated transcription (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN Ino80 Ino80 complex (ortholog); nucleoplasm (ortholog); nucleus (ortholog) | | | | Black Rat | 17 | description | gene, protein-coding, MODEL [RefSeq] |
| 1310558 | Nfrkb | nuclear factor related to kappa B binding protein | ENCODES a protein that exhibits protease binding (ortholog); INVOLVED IN chromatin remodeling (ortholog); positive regulation of DNA repair (ortholog); positive regulation of DNA-templated transcription (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN Ino80 complex (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acrylamide | 8 | 38089574 | 38121506 | Rat | 106 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 8705257 | Nfrkb | nuclear factor related to kappaB binding protein | ENCODES a protein that exhibits protease binding (ortholog); INVOLVED IN chromatin remodeling (ortholog); positive regulation of DNA repair (ortholog); positive regulation of DNA-templated transcription (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN Ino80 complex (ortholog); nucleoplasm (ortholog); nucleus (ortholog) | NW_004955412 | 30817151 | 30848992 | Chinchilla | 19 | description | gene, protein-coding, MODEL [RefSeq] |
| 11848766 | NFRKB | nuclear factor related to kappaB binding protein | ENCODES a protein that exhibits DNA binding (inferred); protease binding (inferred); INVOLVED IN chromatin remodeling (inferred); positive regulation of DNA repair (inferred); positive regulation of DNA-templated transcription (inferred); PARTICIPATES IN INO80 f amily mediated chromatin remodeling pathway; FOUND IN Ino80 complex (inferred); nucleoplasm (inferred); nucleus (inferred) | 11 | 124676456 | 124708349 | Bonobo | 25 | description | gene, protein-coding, MODEL [RefSeq] |
| 12419875 | NFRKB | nuclear factor related to kappaB binding protein | ENCODES a protein that exhibits DNA binding (inferred); protease binding (inferred); INVOLVED IN chromatin remodeling (inferred); positive regulation of DNA repair (inferred); positive regulation of DNA-templated transcription (inferred); PARTICIPATES IN INO80 f amily mediated chromatin remodeling pathway; FOUND IN Ino80 complex (inferred); nucleoplasm (inferred); nucleus (inferred) | 5 | 4944278 | 4982377 | Dog | 25 | description | gene, protein-coding, MODEL [RefSeq] |
| 12472134 | Nfrkb | nuclear factor related to kappaB binding protein | ENCODES a protein that exhibits DNA binding (inferred); protease binding (inferred); INVOLVED IN chromatin remodeling (inferred); positive regulation of DNA repair (inferred); positive regulation of DNA-templated transcription (inferred); PARTICIPATES IN INO80 f amily mediated chromatin remodeling pathway; FOUND IN Ino80 complex (inferred); nucleoplasm (inferred); nucleus (inferred) | NW_004936572 | 2435875 | 2468848 | Squirrel | 25 | description | gene, protein-coding, MODEL [RefSeq] |
| 14273058 | NFRKB | nuclear factor related to kappaB binding protein | ENCODES a protein that exhibits DNA binding (inferred); protease binding (inferred); INVOLVED IN chromatin remodeling (inferred); positive regulation of DNA repair (inferred); positive regulation of DNA-templated transcription (inferred); PARTICIPATES IN INO80 f amily mediated chromatin remodeling pathway; FOUND IN Ino80 complex (inferred); nucleoplasm (inferred); nucleus (inferred) | | | | Pig | 25 | description | gene, protein-coding, MODEL [RefSeq] |
| 18535032 | NFRKB | nuclear factor related to kappaB binding protein | ENCODES a protein that exhibits DNA binding (inferred); protease binding (inferred); INVOLVED IN chromatin remodeling (inferred); positive regulation of DNA repair (inferred); positive regulation of DNA-templated transcription (inferred); PARTICIPATES IN INO80 f amily mediated chromatin remodeling pathway; FOUND IN Ino80 complex (inferred); nucleoplasm (inferred); nucleus (inferred) | | | | Green Monkey | 25 | description | gene, protein-coding, MODEL [RefSeq] |
| 18932025 | Nfrkb | nuclear factor related to kappaB binding protein | ENCODES a protein that exhibits DNA binding (inferred); protease binding (inferred); INVOLVED IN chromatin remodeling (ortholog); positive regulation of DNA repair (ortholog); positive regulation of DNA-templated transcription (ortholog); PARTICIPATES IN INO80 f amily mediated chromatin remodeling pathway; FOUND IN Ino80 complex (ortholog); nucleoplasm (ortholog) | | | | Naked Mole-Rat | 22 | description | gene, protein-coding, MODEL [RefSeq] |
| 626102658 | Nfrkb | nuclear factor related to kappaB binding protein | ENCODES a protein that exhibits protease binding (ortholog); INVOLVED IN chromatin remodeling (ortholog); positive regulation of DNA repair (ortholog); positive regulation of DNA-templated transcription (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN Ino80 complex (ortholog); nucleoplasm (ortholog); nucleus (ortholog) | | | | Black Rat | 19 | description | gene, protein-coding, MODEL [RefSeq] |
| 9014511 | Ruvbl1 | RuvB like AAA ATPase 1 | ENCODES a protein that exhibits 3'-5' DNA helicase activity (ortholog); ADP binding (ortholog); ATP binding (ortholog); INVOLVED IN chromatin remodeling (ortholog); gene expression (ortholog); positive regulation of canonical Wnt signaling pathway (ortholog); PARTICIPATES IN INO80 :700;'>INO80 family mediated chromatin remodeling pathway; FOUND IN ciliary basal body (ortholog); cytosol (ortholog); Ino80 complex (ortholog) | NW_004955429 | 15598465 | 15632290 | Chinchilla | 53 | description | gene, protein-coding, MODEL [RefSeq] |
| 18913348 | Ruvbl1 | RuvB like AAA ATPase 1 | ENCODES a protein that exhibits 3'-5' DNA helicase activity (ortholog); ADP binding (ortholog); ATP hydrolysis activity (ortholog); INVOLVED IN chromatin remodeling (ortholog); gene expression (ortholog); positive regulation of canonical Wnt signaling pathway (ortholog); PARTICIPATES IN INO80 'font-weight:700;'>INO80 family mediated chromatin remodeling pathway; FOUND IN ciliary basal body (ortholog); cytosol (ortholog); Ino80 complex (ortholog) | | | | Naked Mole-Rat | 63 | description | gene, protein-coding, MODEL [RefSeq] |
| 625955304 | Ruvbl1 | RuvB like AAA ATPase 1 | ENCODES a protein that exhibits 3'-5' DNA helicase activity (ortholog); ADP binding (ortholog); ATP binding (ortholog); INVOLVED IN chromatin remodeling (ortholog); gene expression (ortholog); positive regulation of canonical Wnt signaling pathway (ortholog); PARTICIPATES IN INO80 :700;'>INO80 family mediated chromatin remodeling pathway; FOUND IN ciliary basal body (ortholog); cytosol (ortholog); Ino80 complex (ortholog) | | | | Black Rat | 53 | description | gene, protein-coding, MODEL [RefSeq] |
| 8854830 | Tfpt | TCF3 fusion partner | ENCODES a protein that exhibits DNA binding (ortholog); protein kinase binding (ortholog); protein-containing complex binding (ortholog); INVOLVED IN apoptotic process (ortholog); apoptotic signaling pathway (ortholog); chromatin remodeling (ortholog); PARTICIPATES IN INO80 INO80 family mediated chromatin remodeling pathway; FOUND IN actin filament (ortholog); cytoplasm (ortholog); Ino80 complex (ortholog) | NW_004955604 | 136357 | 139799 | Chinchilla | 37 | description | gene, protein-coding, MODEL [RefSeq] |
| 626070239 | Tfpt | TCF3 fusion partner | ENCODES a protein that exhibits DNA binding (ortholog); protein kinase binding (ortholog); protein-containing complex binding (ortholog); INVOLVED IN apoptotic process (ortholog); apoptotic signaling pathway (ortholog); chromatin remodeling (ortholog); PARTICIPATES IN INO80 INO80 family mediated chromatin remodeling pathway; FOUND IN actin filament (ortholog); cytoplasm (ortholog); Ino80 complex (ortholog) | | | | Black Rat | 37 | description | gene, protein-coding, MODEL [RefSeq] |
| 8998210 | Uchl5 | ubiquitin C-terminal hydrolase L5 | ENCODES a protein that exhibits cysteine-type deubiquitinase activity (ortholog); endopeptidase inhibitor activity (ortholog); proteasome binding (ortholog); INVOLVED IN chromatin remodeling (ortholog); forebrain morphogenesis (ortholog); lateral ventricle development (ortholog); PARTICIPATES IN ... (more) an style='font-weight:700;'>INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH alcohol-associated liver disease (ortholog); Experimental Diabetes Mellitus (ortholog); Testis Reperfusion Injury (ortholog); FOUND IN cytosol (ortholog); cytosolic proteasome complex (ortholog); Ino80 complex (ortholog) | NW_004955406 | 30432652 | 30468741 | Chinchilla | 37 | description | gene, protein-coding, MODEL [RefSeq] |
| 13928401 | UCHL5 | ubiquitin C-terminal hydrolase L5 | ENCODES a protein that exhibits cysteine-type deubiquitinase activity (ortholog); INVOLVED IN protein deubiquitination (ortholog); regulation of AMPA receptor activity (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WIT H alcohol-associated liver disease (ortholog); Experimental Diabetes Mellitus (ortholog); Testis Reperfusion Injury (ortholog); FOUND IN cytosol (ortholog); cytosolic proteasome complex (ortholog); Ino80 complex (ortholog) | | | | Pig | 62 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 18925645 | Uchl5 | ubiquitin C-terminal hydrolase L5 | ENCODES a protein that exhibits endopeptidase inhibitor activity (ortholog); INVOLVED IN chromatin remodeling (ortholog); forebrain morphogenesis (ortholog); lateral ventricle development (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pat hway; ASSOCIATED WITH alcohol-associated liver disease (ortholog); Experimental Diabetes Mellitus (ortholog); Testis Reperfusion Injury (ortholog); FOUND IN cytosol (ortholog); cytosolic proteasome complex (ortholog); Ino80 complex (ortholog) | | | | Naked Mole-Rat | 53 | description | gene, protein-coding, MODEL [RefSeq] |
| 625979325 | Uchl5 | ubiquitin C-terminal hydrolase L5 | ENCODES a protein that exhibits cysteine-type deubiquitinase activity (ortholog); endopeptidase inhibitor activity (ortholog); proteasome binding (ortholog); INVOLVED IN chromatin remodeling (ortholog); forebrain morphogenesis (ortholog); lateral ventricle development (ortholog); PARTICIPATES IN ... (more) an style='font-weight:700;'>INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH alcohol-associated liver disease (ortholog); Experimental Diabetes Mellitus (ortholog); Testis Reperfusion Injury (ortholog); FOUND IN cytosol (ortholog); cytosolic proteasome complex (ortholog); Ino80 complex (ortholog) | | | | Black Rat | 37 | description | gene, protein-coding, MODEL [RefSeq] |
| 628837 | Actb | actin, beta | ENCODES a protein that exhibits protein kinase binding; ATP hydrolysis activity (ortholog); identical protein binding (ortholog); INVOLVED IN axonogenesis; cellular response to electrical stimulus; circadian rhythm; PARTICIPATES IN auditory mechanotransduction pathway; INO80 >INO80 family mediated chromatin remodeling pathway; mitochondria transport pathway; ASSOCIATED WITH Chemical and Drug Induced Liver Injury; Febrile Seizures; metabolic dysfunction-associated steatotic liver disease; FOUND IN axon; cytoskeleton; membrane raft; INTERACTS WITH (+)-catechin; (+)-epicatechin-3-O-gallate; (3,4-dihydroxyphenyl)acetic acid | 12 | 16776664 | 16779634 | Rat | 533 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 8979037 | Actb | actin beta | ENCODES a protein that exhibits ATP hydrolysis activity (ortholog); identical protein binding (ortholog); kinesin binding (ortholog); INVOLVED IN adherens junction assembly (ortholog); apical protein localization (ortholog); axonogenesis (ortholog); PARTICIPATES IN auditory mechanotransduction pathw ay; INO80 family mediated chromatin remodeling pathway; mitochondria transport pathway; ASSOCIATED WITH Aminoacylase 1 Deficiency (ortholog); Animal Mammary Neoplasms (ortholog); Baraitser-Winter syndrome (ortholog); FOUND IN actin cytoskeleton (ortholog); adherens junction (ortholog); apical junction complex (ortholog) | NW_004955460 | 10358100 | 10361585 | Chinchilla | 173 | description | gene, protein-coding, MODEL [RefSeq] |
| 12261807 | ACTB | actin beta | ENCODES a protein that exhibits ATP hydrolysis activity (ortholog); identical protein binding (ortholog); kinesin binding (ortholog); INVOLVED IN adherens junction assembly (ortholog); apical protein localization (ortholog); axonogenesis (ortholog); PARTICIPATES IN auditory mechanotransduction pathw ay; INO80 family mediated chromatin remodeling pathway; mitochondria transport pathway; ASSOCIATED WITH Aminoacylase 1 Deficiency (ortholog); Animal Mammary Neoplasms (ortholog); Baraitser-Winter syndrome (ortholog); FOUND IN actin cytoskeleton (ortholog); adherens junction (ortholog); apical junction complex (ortholog) | 6 | 12421006 | 12424449 | Dog | 180 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 12549240 | Actb | actin beta | ENCODES a protein that exhibits protein kinase binding (ortholog); INVOLVED IN axonogenesis (ortholog); cellular response to electrical stimulus (ortholog); circadian rhythm (ortholog); PARTICIPATES IN auditory mechanotransduction pathway; INO80 family mediated chromatin remodeling pathway; mitochondria transport pathway; ASSOCIATED WITH Aminoacylase 1 Deficiency (ortholog); Animal Mammary Neoplasms (ortholog); Baraitser-Winter syndrome (ortholog); FOUND IN axon (ortholog); cytoskeleton (ortholog); dense body (ortholog) | NW_004936765 | 667107 | 670627 | Squirrel | 176 | description | gene, protein-coding, MODEL [RefSeq] |
| 14023381 | ACTB | actin beta | ENCODES a protein that exhibits protein kinase binding (ortholog); INVOLVED IN microtubule-based process; axonogenesis (ortholog); cellular response to electrical stimulus (ortholog); PARTICIPATES IN auditory mechanotransduction pathway; INO80 family mediated ch romatin remodeling pathway; mitochondria transport pathway; ASSOCIATED WITH Aminoacylase 1 Deficiency (ortholog); Animal Mammary Neoplasms (ortholog); Baraitser-Winter syndrome (ortholog); FOUND IN actin cytoskeleton (ortholog); axon (ortholog); cytoskeleton (ortholog); INTERACTS WITH deoxynivalenol | | | | Pig | 134 | description | gene, protein-coding, MODEL [RefSeq] |
| 18505767 | ACTB | actin beta | ENCODES a protein that exhibits ATP hydrolysis activity (ortholog); identical protein binding (ortholog); kinesin binding (ortholog); INVOLVED IN adherens junction assembly (ortholog); apical protein localization (ortholog); axonogenesis (ortholog); PARTICIPATES IN auditory mechanotransduction pathw ay; INO80 family mediated chromatin remodeling pathway; mitochondria transport pathway; ASSOCIATED WITH Aminoacylase 1 Deficiency (ortholog); Animal Mammary Neoplasms (ortholog); Baraitser-Winter syndrome (ortholog); FOUND IN actin cytoskeleton (ortholog); adherens junction (ortholog); apical junction complex (ortholog) | | | | Green Monkey | 172 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 18919549 | Actb | actin beta | ENCODES a protein that exhibits ATP hydrolysis activity (ortholog); identical protein binding (ortholog); kinesin binding (ortholog); INVOLVED IN adherens junction assembly (ortholog); apical protein localization (ortholog); axonogenesis (ortholog); PARTICIPATES IN auditory mechanotransduction pathw ay; INO80 family mediated chromatin remodeling pathway; mitochondria transport pathway; ASSOCIATED WITH Aminoacylase 1 Deficiency (ortholog); Animal Mammary Neoplasms (ortholog); Baraitser-Winter syndrome (ortholog); FOUND IN actin cytoskeleton (ortholog); adherens junction (ortholog); apical junction complex (ortholog) | | | | Naked Mole-Rat | 177 | description | gene, protein-coding, MODEL [RefSeq] |
| 329331335 | ACTB | actin beta | ENCODES a protein that exhibits ATP hydrolysis activity (ortholog); identical protein binding (ortholog); kinesin binding (ortholog); INVOLVED IN adherens junction assembly (ortholog); apical protein localization (ortholog); axonogenesis (ortholog); PARTICIPATES IN auditory mechanotransduction pathw ay; INO80 family mediated chromatin remodeling pathway; mitochondria transport pathway; ASSOCIATED WITH Aminoacylase 1 Deficiency (ortholog); Animal Mammary Neoplasms (ortholog); Baraitser-Winter syndrome (ortholog); FOUND IN actin cytoskeleton (ortholog); adherens junction (ortholog); apical junction complex (ortholog) | | | | Bonobo | 173 | description | gene, protein-coding, MODEL [RefSeq] |
| 626116364 | Actb | actin beta | ENCODES a protein that exhibits ATP hydrolysis activity (ortholog); identical protein binding (ortholog); kinesin binding (ortholog); INVOLVED IN adherens junction assembly (ortholog); apical protein localization (ortholog); axonogenesis (ortholog); PARTICIPATES IN auditory mechanotransduction pathw ay; INO80 family mediated chromatin remodeling pathway; mitochondria transport pathway; ASSOCIATED WITH Aminoacylase 1 Deficiency (ortholog); Animal Mammary Neoplasms (ortholog); Baraitser-Winter syndrome (ortholog); FOUND IN actin cytoskeleton (ortholog); adherens junction (ortholog); apical junction complex (ortholog) | | | | Black Rat | 172 | description | gene, protein-coding, MODEL [RefSeq] |
| 1317454 | Actr5 | ARP5 actin-related protein 5 | Involved in positive regulation of DNA metabolic process; regulation of embryonic development; and telomere maintenance. Predicted to be located in nucleus. Predicted to be part of Ino80 complex. Predicted to be active in cytoplasm. Is expressed in bone; brain; cartilage; and genitourinary system. Orthologous to human ACTR5 (actin related protein 5). [provided by Alliance of Genome Resources, Jul 2025] | 2 | 158466800 | 158481131 | Mouse | 80 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1304609 | Actr6 | actin related protein 6 | INVOLVED IN nucleolus organization (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN nucleolus (ortholog); Swr1 complex (ortholog); INTERACTS WITH 17beta-estradiol; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 7 | 26037574 | 26058362 | Rat | 70 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 9034052 | Actr6 | actin related protein 6 | INVOLVED IN nucleolus organization (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN nucleolus (ortholog); Swr1 complex (ortholog) | NW_004955405 | 35942690 | 35962422 | Chinchilla | 7 | description | gene, protein-coding, MODEL [RefSeq] |
| 11952825 | ACTR6 | actin related protein 6 | INVOLVED IN DNA-templated transcription (inferred); nucleolus organization (inferred); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN cytoskeleton (inferred); nucleolus (inferred); nucleus (inferred) | 12 | 97781017 | 97806049 | Bonobo | 11 | description | gene, protein-coding, MODEL [RefSeq] |
| 12203187 | ACTR6 | actin related protein 6 | INVOLVED IN nucleolus organization (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN cytoplasm (inferred); cytoskeleton (inferred); nucleolus (inferred) | 15 | 39312863 | 39342208 | Dog | 12 | description | gene, protein-coding, MODEL [RefSeq] |
| 12707100 | Actr6 | actin related protein 6 | INVOLVED IN DNA-templated transcription (inferred); nucleolus organization (inferred); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN nucleus (ortholog) | NW_004936492 | 13594417 | 13616528 | Squirrel | 12 | description | gene, protein-coding, MODEL [RefSeq] |
| 14284795 | ACTR6 | actin related protein 6 | INVOLVED IN DNA-templated transcription (inferred); nucleolus organization (inferred); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN cytoskeleton (inferred); nucleolus (inferred); nucleus (inferred) | | | | Pig | 14 | description | gene, protein-coding, MODEL [RefSeq] |
| 18777901 | ACTR6 | actin related protein 6 | INVOLVED IN DNA-templated transcription (inferred); nucleolus organization (inferred); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN cytoskeleton (inferred); nucleolus (inferred); nucleus (inferred) | | | | Green Monkey | 11 | description | gene, protein-coding, MODEL [RefSeq] |
| 18905256 | Actr6 | actin related protein 6 | INVOLVED IN nucleolus organization (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN nucleus (ortholog); Swr1 complex (ortholog) | | | | Naked Mole-Rat | 11 | description | gene, protein-coding, MODEL [RefSeq] |
| 625951760 | Actr6 | actin related protein 6 | INVOLVED IN nucleolus organization (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN nucleolus (ortholog); Swr1 complex (ortholog) | | | | Black Rat | 7 | description | gene, protein-coding, MODEL [RefSeq] |
| 1323564 | Actr8 | ARP8 actin-related protein 8 | Predicted to enable ATP binding activity. Involved in positive regulation of DNA metabolic process; regulation of embryonic development; and telomere maintenance. Predicted to be located in centrosome and nucleoplasm. Predicted to be part of Ino80 complex. Is ex pressed in several structures, including early conceptus; liver; metanephros; and oocyte. Orthologous to human ACTR8 (actin related protein 8). [provided by Alliance of Genome Resources, Jul 2025] | 14 | 29700294 | 29717409 | Mouse | 108 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1307003 | Brd8 | bromodomain containing 8 | ENCODES a protein that exhibits nuclear thyroid hormone receptor binding (ortholog); transcription coactivator activity (ortholog); INVOLVED IN positive regulation of transcription by RNA polymerase II; cellular response to thyroid hormone stimulus (ortholog); positive regulation of double-strand br eak repair via homologous recombination (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH colorectal adenocarcinoma; endometriosis (ortholog); FOUND IN NuA4 histone acetyltransferase complex (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; Butylbenzyl phthalate | 18 | 26455824 | 26504106 | Rat | 114 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 8882702 | Brd8 | bromodomain containing 8 | ENCODES a protein that exhibits nuclear thyroid hormone receptor binding (ortholog); transcription coactivator activity (ortholog); INVOLVED IN cellular response to thyroid hormone stimulus (ortholog); positive regulation of double-strand break repair via homologous recombination (ortholog); positiv e regulation of transcription by RNA polymerase II (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH colorectal adenocarcinoma (ortholog); endometriosis (ortholog); FOUND IN NuA4 histone acetyltransferase complex (ortholog); nucleoplasm (ortholog); nucleus (ortholog) | NW_004955418 | 2232853 | 2275812 | Chinchilla | 17 | description | gene, protein-coding, MODEL [RefSeq] |
| 11800786 | BRD8 | bromodomain containing 8 | ENCODES a protein that exhibits nuclear thyroid hormone receptor binding (inferred); transcription coactivator activity (inferred); INVOLVED IN positive regulation of transcription by RNA polymerase II (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH colorectal adenocarcinoma (ortholog); endometriosis (ortholog); FOUND IN NuA4 histone acetyltransferase complex (inferred); nucleoplasm (inferred); nucleus (inferred) | 5 | 133535321 | 133557304 | Bonobo | 21 | description | gene, protein-coding, MODEL [RefSeq] |
| 12064692 | BRD8 | bromodomain containing 8 | ENCODES a protein that exhibits nuclear thyroid hormone receptor binding (inferred); transcription coactivator activity (inferred); INVOLVED IN positive regulation of transcription by RNA polymerase II (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH colorectal adenocarcinoma (ortholog); endometriosis (ortholog); FOUND IN NuA4 histone acetyltransferase complex (inferred); nucleoplasm (inferred); nucleus (inferred) | 11 | 25793375 | 25825868 | Dog | 21 | description | gene, protein-coding, MODEL [RefSeq] |
| 12672641 | Brd8 | bromodomain containing 8 | ENCODES a protein that exhibits nuclear thyroid hormone receptor binding (ortholog); transcription coactivator activity (ortholog); INVOLVED IN cellular response to thyroid hormone stimulus (ortholog); positive regulation of double-strand break repair via homologous recombination (ortholog); positiv e regulation of transcription by RNA polymerase II (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH colorectal adenocarcinoma (ortholog); endometriosis (ortholog); FOUND IN nucleoplasm (ortholog); Swr1 complex (ortholog) | NW_004936531 | 7333974 | 7361855 | Squirrel | 19 | description | gene, protein-coding, MODEL [RefSeq] |
| 13940945 | BRD8 | bromodomain containing 8 | ENCODES a protein that exhibits nuclear thyroid hormone receptor binding (inferred); transcription coactivator activity (inferred); INVOLVED IN positive regulation of transcription by RNA polymerase II (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH colorectal adenocarcinoma (ortholog); endometriosis (ortholog); FOUND IN NuA4 histone acetyltransferase complex (inferred); nucleoplasm (inferred); nucleus (inferred) | | | | Pig | 21 | description | gene, protein-coding, MODEL [RefSeq] |
| 18759268 | BRD8 | bromodomain containing 8 | ENCODES a protein that exhibits nuclear thyroid hormone receptor binding (inferred); transcription coactivator activity (inferred); INVOLVED IN positive regulation of transcription by RNA polymerase II (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH colorectal adenocarcinoma (ortholog); endometriosis (ortholog); FOUND IN NuA4 histone acetyltransferase complex (inferred); nucleoplasm (inferred); nucleus (inferred) | | | | Green Monkey | 21 | description | gene, protein-coding, MODEL [RefSeq] |
| 18918658 | Brd8 | bromodomain containing 8 | ENCODES a protein that exhibits nuclear thyroid hormone receptor binding (ortholog); transcription coactivator activity (ortholog); INVOLVED IN cellular response to thyroid hormone stimulus (ortholog); positive regulation of double-strand break repair via homologous recombination (ortholog); positiv e regulation of transcription by RNA polymerase II (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH colorectal adenocarcinoma (ortholog); endometriosis (ortholog); FOUND IN nucleoplasm (ortholog); Swr1 complex (ortholog) | | | | Naked Mole-Rat | 19 | description | gene, protein-coding, MODEL [RefSeq] |
| 626162052 | Brd8 | bromodomain containing 8 | ENCODES a protein that exhibits nuclear thyroid hormone receptor binding (ortholog); transcription coactivator activity (ortholog); INVOLVED IN cellular response to thyroid hormone stimulus (ortholog); positive regulation of double-strand break repair via homologous recombination (ortholog); positiv e regulation of transcription by RNA polymerase II (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH colorectal adenocarcinoma (ortholog); endometriosis (ortholog); FOUND IN NuA4 histone acetyltransferase complex (ortholog); nucleoplasm (ortholog); nucleus (ortholog) | | | | Black Rat | 17 | description | gene, protein-coding, MODEL [RefSeq] |
| 1311295 | Dmap1 | DNA methyltransferase 1-associated protein 1 | ENCODES a protein that exhibits RNA polymerase II-specific DNA-binding transcription factor binding (ortholog); transcription corepressor activity (ortholog); INVOLVED IN response to ethanol; negative regulation of transcription by RNA polymerase II (ortholog); positive regulation of double-strand b reak repair via homologous recombination (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH epilepsy (ortholog); Muscle Hypotonia (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); NuA4 histone acetyltransferase complex (ortholog); INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; bisphenol A | 5 | 136380211 | 136388229 | Rat | 91 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 8773277 | Dmap1 | DNA methyltransferase 1 associated protein 1 | ENCODES a protein that exhibits RNA polymerase II-specific DNA-binding transcription factor binding (ortholog); transcription corepressor activity (ortholog); INVOLVED IN negative regulation of transcription by RNA polymerase II (ortholog); positive regulation of double-strand break repair via homol ogous recombination (ortholog); positive regulation of protein import into nucleus (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH epilepsy (ortholog); Muscle Hypotonia (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); NuA4 histone acetyltransferase complex (ortholog) | NW_004955464 | 13984748 | 13993411 | Chinchilla | 21 | description | gene, protein-coding, MODEL [RefSeq] |
| 12038937 | DMAP1 | DNA methyltransferase 1 associated protein 1 | ENCODES a protein that exhibits RNA polymerase II-specific DNA-binding transcription factor binding (inferred); transcription corepressor activity (inferred); INVOLVED IN negative regulation of transcription by RNA polymerase II (ortholog); response to ethanol (ortholog); PARTICIPATES IN INO80 ='font-weight:700;'>INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH epilepsy (ortholog); Muscle Hypotonia (ortholog); FOUND IN chromosome (inferred); cytoplasm (inferred); cytosol (inferred) | 1 | 43516839 | 43524206 | Bonobo | 34 | description | gene, protein-coding, MODEL [RefSeq] |
| 12351897 | DMAP1 | DNA methyltransferase 1 associated protein 1 | ENCODES a protein that exhibits RNA polymerase II-specific DNA-binding transcription factor binding (inferred); transcription corepressor activity (inferred); INVOLVED IN negative regulation of transcription by RNA polymerase II (ortholog); response to ethanol (ortholog); PARTICIPATES IN INO80 ='font-weight:700;'>INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH epilepsy (ortholog); Muscle Hypotonia (ortholog); FOUND IN chromosome (inferred); cytoplasm (inferred); cytosol (inferred) | 15 | 16077164 | 16085666 | Dog | 34 | description | gene, protein-coding, MODEL [RefSeq] |
| 12512342 | Dmap1 | DNA methyltransferase 1 associated protein 1 | ENCODES a protein that exhibits RNA polymerase II-specific DNA-binding transcription factor binding (inferred); transcription corepressor activity (inferred); INVOLVED IN negative regulation of transcription by RNA polymerase II (ortholog); response to ethanol (ortholog); PARTICIPATES IN INO80 ='font-weight:700;'>INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH epilepsy (ortholog); Muscle Hypotonia (ortholog); FOUND IN chromosome (inferred); cytoplasm (inferred); cytosol (inferred) | NW_004936474 | 25486447 | 25495909 | Squirrel | 34 | description | gene, protein-coding, MODEL [RefSeq] |
| 14098301 | DMAP1 | DNA methyltransferase 1 associated protein 1 | ENCODES a protein that exhibits methyltransferase activity (inferred); RNA polymerase II-specific DNA-binding transcription factor binding (inferred); transcription corepressor activity (inferred); INVOLVED IN negative regulation of transcription by RNA polymerase II (ortholog); response to ethanol (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH epilepsy (ortholog); Muscle Hypotonia (ortholog); FOUND IN chromosome (inferred); cytoplasm (inferred); cytosol (inferred) | | | | Pig | 37 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 18748060 | DMAP1 | DNA methyltransferase 1 associated protein 1 | ENCODES a protein that exhibits RNA polymerase II-specific DNA-binding transcription factor binding (inferred); transcription corepressor activity (inferred); INVOLVED IN negative regulation of transcription by RNA polymerase II (ortholog); response to ethanol (ortholog); PARTICIPATES IN INO80 ='font-weight:700;'>INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH epilepsy (ortholog); Muscle Hypotonia (ortholog); FOUND IN chromosome (inferred); cytoplasm (inferred); cytosol (inferred) | | | | Green Monkey | 34 | description | gene, protein-coding, MODEL [RefSeq] |
| 18932208 | Dmap1 | DNA methyltransferase 1 associated protein 1 | ENCODES a protein that exhibits RNA polymerase II-specific DNA-binding transcription factor binding (ortholog); INVOLVED IN negative regulation of transcription by RNA polymerase II (ortholog); positive regulation of double-strand break repair via homologous recombination (ortholog); positive regula tion of protein import into nucleus (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH epilepsy (ortholog); Muscle Hypotonia (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); nucleoplasm (ortholog) | | | | Naked Mole-Rat | 33 | description | gene, protein-coding, MODEL [RefSeq] |
| 626063233 | Dmap1 | DNA methyltransferase 1 associated protein 1 | ENCODES a protein that exhibits RNA polymerase II-specific DNA-binding transcription factor binding (ortholog); transcription corepressor activity (ortholog); INVOLVED IN negative regulation of transcription by RNA polymerase II (ortholog); positive regulation of double-strand break repair via homol ogous recombination (ortholog); positive regulation of protein import into nucleus (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH epilepsy (ortholog); Muscle Hypotonia (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); NuA4 histone acetyltransferase complex (ortholog) | | | | Black Rat | 21 | description | gene, protein-coding, MODEL [RefSeq] |
| 1304733 | Ep400 | E1A binding protein p400 | ENCODES a protein that exhibits chromatin binding; protein antigen binding; INVOLVED IN gene expression (ortholog); nervous system development (ortholog); positive regulation of double-strand break repair via homologous recombination (ortholog); PARTICIPATES IN INO80 span> family mediated chromatin remodeling pathway; ASSOCIATED WITH Neurodevelopmental Disorders (ortholog); FOUND IN NuA4 histone acetyltransferase complex (ortholog); nuclear speck (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 4-amino-2,6-dinitrotoluene | 12 | 51551665 | 51658635 | Rat | 136 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 8707427 | Ep400 | E1A binding protein p400 | ENCODES a protein that exhibits chromatin binding (ortholog); protein antigen binding (ortholog); INVOLVED IN gene expression (ortholog); nervous system development (ortholog); positive regulation of double-strand break repair via homologous recombination (ortholog); PARTICIPATES IN INO80 t-weight:700;'>INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH Neurodevelopmental Disorders (ortholog); FOUND IN NuA4 histone acetyltransferase complex (ortholog); nuclear speck (ortholog); nucleoplasm (ortholog) | NW_004955482 | 639316 | 746331 | Chinchilla | 19 | description | gene, protein-coding, MODEL [RefSeq] |
| 12432924 | EP400 | E1A binding protein p400 | ENCODES a protein that exhibits chromatin binding (ortholog); protein antigen binding (ortholog); INVOLVED IN gene expression (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH Neurodevelopmental Disorders (ortholog); FOUND IN NuA4 histone acetyltransferase complex (inferred); nuclear speck (inferred); nucleoplasm (inferred) | 26 | 848028 | 951135 | Dog | 45 | description | gene, protein-coding, MODEL [RefSeq] |
| 12696652 | Ep400 | E1A binding protein p400 | ENCODES a protein that exhibits chromatin binding (ortholog); protein antigen binding (ortholog); INVOLVED IN gene expression (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH Neurodevelopmental Disorders (ortholog); FOUND IN NuA4 histone acetyltransferase complex (inferred); nuclear speck (inferred); nucleoplasm (inferred) | NW_004936660 | 2212063 | 2297730 | Squirrel | 32 | description | gene, protein-coding, MODEL [RefSeq] |
| 14016151 | EP400 | E1A binding protein p400 | ENCODES a protein that exhibits chromatin binding (ortholog); protein antigen binding (ortholog); INVOLVED IN gene expression (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH Neurodevelopmental Disorders (ortholog); FOUND IN NuA4 histone acetyltransferase complex (inferred); nuclear speck (inferred); nucleoplasm (inferred) | | | | Pig | 32 | description | gene, protein-coding, MODEL [RefSeq] |
| 18674426 | EP400 | E1A binding protein p400 | ENCODES a protein that exhibits chromatin binding (ortholog); protein antigen binding (ortholog); INVOLVED IN gene expression (ortholog); nervous system development (ortholog); positive regulation of double-strand break repair via homologous recombination (ortholog); PARTICIPATES IN INO80 t-weight:700;'>INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH Neurodevelopmental Disorders (ortholog); FOUND IN nuclear speck (ortholog) | | | | Green Monkey | 29 | description | gene, protein-coding, MODEL [RefSeq] |
| 18902441 | Ep400 | E1A binding protein p400 | ENCODES a protein that exhibits chromatin binding (ortholog); protein antigen binding (ortholog); INVOLVED IN gene expression (ortholog); nervous system development (ortholog); positive regulation of double-strand break repair via homologous recombination (ortholog); PARTICIPATES IN INO80 t-weight:700;'>INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH Neurodevelopmental Disorders (ortholog); FOUND IN nuclear speck (ortholog) | | | | Naked Mole-Rat | 29 | description | gene, protein-coding, MODEL [RefSeq] |
| 626025922 | Ep400 | E1A binding protein p400 | ENCODES a protein that exhibits chromatin binding (ortholog); protein antigen binding (ortholog); INVOLVED IN gene expression (ortholog); nervous system development (ortholog); positive regulation of double-strand break repair via homologous recombination (ortholog); PARTICIPATES IN INO80 t-weight:700;'>INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH Neurodevelopmental Disorders (ortholog); FOUND IN NuA4 histone acetyltransferase complex (ortholog); nuclear speck (ortholog); nucleoplasm (ortholog) | | | | Black Rat | 19 | description | gene, protein-coding, MODEL [RefSeq] |
| 2324280 | Epc1 | enhancer of polycomb 1 | ENCODES a protein that exhibits chromatin-protein adaptor activity (ortholog); enzyme-substrate adaptor activity (ortholog); INVOLVED IN vascular associated smooth muscle cell differentiation; double-strand break repair via homologous recombination (ortholog); negative regulation of DNA-templated tr anscription (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH Neointima (ortholog); FOUND IN NuA4 histone acetyltransferase complex (ortholog); nuclear body (ortholog); nuclear membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; bisphenol A | 17 | 59198513 | 59289535 | Rat | 103 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 8931860 | Epc1 | enhancer of polycomb homolog 1 | ENCODES a protein that exhibits chromatin-protein adaptor activity (ortholog); enzyme-substrate adaptor activity (ortholog); INVOLVED IN double-strand break repair via homologous recombination (ortholog); negative regulation of DNA-templated transcription (ortholog); negative regulation of gene expr ession, epigenetic (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH Neointima (ortholog); FOUND IN NuA4 histone acetyltransferase complex (ortholog); nuclear body (ortholog); nuclear membrane (ortholog) | NW_004955429 | 23819261 | 23910279 | Chinchilla | 28 | description | gene, protein-coding, MODEL [RefSeq] |
| 11984990 | EPC1 | enhancer of polycomb homolog 1 | ENCODES a protein that exhibits chromatin-protein adaptor activity (inferred); enzyme-substrate adaptor activity (inferred); INVOLVED IN negative regulation of gene expression, epigenetic (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); positive regulation of transcr iption by RNA polymerase II (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH Neointima (ortholog); FOUND IN histone acetyltransferase complex (inferred); NuA4 histone acetyltransferase complex (inferred); nuclear body (inferred) | 10 | 32398557 | 32509146 | Bonobo | 35 | description | gene, protein-coding, MODEL [RefSeq] |
| 12264107 | EPC1 | enhancer of polycomb homolog 1 | ENCODES a protein that exhibits chromatin-protein adaptor activity (ortholog); enzyme-substrate adaptor activity (ortholog); INVOLVED IN double-strand break repair via homologous recombination (ortholog); negative regulation of DNA-templated transcription (ortholog); negative regulation of gene expr ession, epigenetic (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH Neointima (ortholog); FOUND IN nuclear body (ortholog); nuclear membrane (ortholog); nucleolus (ortholog) | 2 | 14566177 | 14659774 | Dog | 37 | description | gene, protein-coding, MODEL [RefSeq] |
| 12724427 | Epc1 | enhancer of polycomb homolog 1 | ENCODES a protein that exhibits chromatin-protein adaptor activity (inferred); enzyme-substrate adaptor activity (inferred); INVOLVED IN negative regulation of gene expression, epigenetic (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); positive regulation of transcr iption by RNA polymerase II (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH Neointima (ortholog); FOUND IN histone acetyltransferase complex (inferred); NuA4 histone acetyltransferase complex (inferred); nuclear body (inferred) | NW_004936574 | 966655 | 1050537 | Squirrel | 35 | description | gene, protein-coding, MODEL [RefSeq] |
| 14034486 | EPC1 | enhancer of polycomb homolog 1 | ENCODES a protein that exhibits chromatin-protein adaptor activity (inferred); enzyme-substrate adaptor activity (inferred); INVOLVED IN negative regulation of gene expression, epigenetic (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); positive regulation of transcr iption by RNA polymerase II (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH Neointima (ortholog); FOUND IN histone acetyltransferase complex (inferred); NuA4 histone acetyltransferase complex (inferred); nuclear body (inferred) | | | | Pig | 40 | description | gene, protein-coding, MODEL [RefSeq] |
| 18520575 | EPC1 | enhancer of polycomb homolog 1 | ENCODES a protein that exhibits chromatin-protein adaptor activity (inferred); enzyme-substrate adaptor activity (inferred); INVOLVED IN negative regulation of gene expression, epigenetic (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); positive regulation of transcr iption by RNA polymerase II (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH Neointima (ortholog); FOUND IN NuA4 histone acetyltransferase complex (inferred); nuclear body (inferred); nuclear membrane (inferred) | | | | Green Monkey | 34 | description | gene, protein-coding, MODEL [RefSeq] |
| 18908076 | Epc1 | enhancer of polycomb homolog 1 | ENCODES a protein that exhibits chromatin-protein adaptor activity (ortholog); enzyme-substrate adaptor activity (ortholog); INVOLVED IN double-strand break repair via homologous recombination (ortholog); negative regulation of DNA-templated transcription (ortholog); negative regulation of gene expr ession, epigenetic (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH Neointima (ortholog); FOUND IN nuclear body (ortholog); nuclear membrane (ortholog); nucleolus (ortholog) | | | | Naked Mole-Rat | 32 | description | gene, protein-coding, MODEL [RefSeq] |
| 625970759 | Epc1 | enhancer of polycomb homolog 1 | ENCODES a protein that exhibits chromatin-protein adaptor activity (ortholog); enzyme-substrate adaptor activity (ortholog); INVOLVED IN double-strand break repair via homologous recombination (ortholog); negative regulation of DNA-templated transcription (ortholog); negative regulation of gene expr ession, epigenetic (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH Neointima (ortholog); FOUND IN NuA4 histone acetyltransferase complex (ortholog); nuclear body (ortholog); nuclear membrane (ortholog) | | | | Black Rat | 28 | description | gene, protein-coding, MODEL [RefSeq] |
| 1307271 | Epc2 | enhancer of polycomb 2 | INVOLVED IN positive regulation of double-strand break repair via homologous recombination (ortholog); regulation of cell cycle (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH type 2 diabetes mellitus (ortholog); F OUND IN NuA4 histone acetyltransferase complex (inferred); nucleus (inferred); INTERACTS WITH 6-propyl-2-thiouracil; amitrole; atrazine | 3 | 54276187 | 54376373 | Rat | 89 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 8795159 | Epc2 | enhancer of polycomb 2 | INVOLVED IN positive regulation of double-strand break repair via homologous recombination (ortholog); regulation of cell cycle (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH type 2 diabetes mellitus (ortholog) | NW_004955440 | 14573960 | 14645171 | Chinchilla | 4 | description | gene, protein-coding, MODEL [RefSeq] |
| 11975114 | EPC2 | enhancer of polycomb 2 | INVOLVED IN chromatin organization (inferred); DNA-templated transcription (inferred); positive regulation of double-strand break repair via homologous recombination (inferred); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH type 2 diabetes mellitus (ortholog); FOUND IN NuA4 histone acetyltransferase complex (inferred); nucleus (inferred) | 2B | 11074397 | 11218181 | Bonobo | 10 | description | gene, protein-coding, MODEL [RefSeq] |
| 12262168 | EPC2 | enhancer of polycomb homolog 2 | INVOLVED IN chromatin organization (inferred); DNA-templated transcription (inferred); positive regulation of double-strand break repair via homologous recombination (inferred); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH type 2 diabetes mellitus (ortholog); FOUND IN NuA4 histone acetyltransferase complex (inferred); nucleus (inferred) | 19 | 50356490 | 50484405 | Dog | 15 | description | gene, protein-coding, MODEL [RefSeq] |
| 12584663 | Epc2 | enhancer of polycomb 2 | INVOLVED IN chromatin organization (inferred); DNA-templated transcription (inferred); positive regulation of double-strand break repair via homologous recombination (inferred); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH type 2 diabetes mellitus (ortholog); FOUND IN NuA4 histone acetyltransferase complex (inferred); nucleus (inferred) | NW_004936469 | 28489620 | 28625975 | Squirrel | 10 | description | gene, protein-coding, MODEL [RefSeq] |
| 13945867 | EPC2 | enhancer of polycomb homolog 2 | INVOLVED IN chromatin organization (inferred); DNA-templated transcription (inferred); positive regulation of double-strand break repair via homologous recombination (inferred); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH type 2 diabetes mellitus (ortholog); FOUND IN NuA4 histone acetyltransferase complex (inferred); nucleus (inferred) | | | | Pig | 15 | description | gene, protein-coding, MODEL [RefSeq] |
| 18776576 | EPC2 | enhancer of polycomb 2 | INVOLVED IN chromatin organization (inferred); DNA-templated transcription (inferred); positive regulation of double-strand break repair via homologous recombination (inferred); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH type 2 diabetes mellitus (ortholog); FOUND IN NuA4 histone acetyltransferase complex (inferred); nucleus (inferred) | | | | Green Monkey | 10 | description | gene, protein-coding, MODEL [RefSeq] |
| 18924450 | Epc2 | enhancer of polycomb 2 | INVOLVED IN chromatin organization (inferred); DNA-templated transcription (inferred); positive regulation of double-strand break repair via homologous recombination (inferred); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH type 2 diabetes mellitus (ortholog); FOUND IN NuA4 histone acetyltransferase complex (inferred); nucleus (inferred) | | | | Naked Mole-Rat | 10 | description | gene, protein-coding, MODEL [RefSeq] |
| 625988831 | Epc2 | enhancer of polycomb 2 | INVOLVED IN positive regulation of double-strand break repair via homologous recombination (ortholog); regulation of cell cycle (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH type 2 diabetes mellitus (ortholog) | | | | Black Rat | 4 | description | gene, protein-coding, MODEL [RefSeq] |
| 1310556 | Ing3 | inhibitor of growth family, member 3 | ENCODES a protein that exhibits histone H2A acetyltransferase activity (ortholog); histone H3K4me3 reader activity (ortholog); histone H4 acetyltransferase activity (ortholog); INVOLVED IN positive regulation of double-strand break repair via homologous recombination (ortholog); regulation of cell c ycle (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH hepatocellular carcinoma; FOUND IN NuA4 histone acetyltransferase complex (ortholog); nucleoplasm (ortholog); piccolo histone acetyltransferase complex (ortholog); INTERACTS WITH (+)-schisandrin B; acrylamide; amitrole | 4 | 51439218 | 51469502 | Rat | 121 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 8714507 | Ing3 | inhibitor of growth family member 3 | ENCODES a protein that exhibits histone H2A acetyltransferase activity (ortholog); histone H3K4me3 reader activity (ortholog); histone H4 acetyltransferase activity (ortholog); INVOLVED IN positive regulation of double-strand break repair via homologous recombination (ortholog); regulation of cell c ycle (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH hepatocellular carcinoma (ortholog); FOUND IN NuA4 histone acetyltransferase complex (ortholog); nucleoplasm (ortholog); piccolo histone acetyltransferase complex (ortholog) | NW_004955479 | 2741554 | 2771524 | Chinchilla | 17 | description | gene, protein-coding, MODEL [RefSeq] |
| 11887681 | ING3 | inhibitor of growth family member 3 | ENCODES a protein that exhibits histone H2A acetyltransferase activity (inferred); histone H3K4me3 reader activity (inferred); histone H4 acetyltransferase activity (inferred); INVOLVED IN chromatin organization (inferred); chromatin remodeling (inferred); DNA-templated transcription (inferred); PAR TICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH hepatocellular carcinoma (ortholog); FOUND IN NuA4 histone acetyltransferase complex (inferred); nucleoplasm (inferred); nucleus (inferred) | 7 | 112955848 | 112984473 | Bonobo | 26 | description | gene, protein-coding, MODEL [RefSeq] |
| 12358492 | ING3 | inhibitor of growth family member 3 | ENCODES a protein that exhibits histone H2A acetyltransferase activity (inferred); histone H3K4me3 reader activity (inferred); histone H4 acetyltransferase activity (inferred); INVOLVED IN chromatin organization (inferred); chromatin remodeling (inferred); DNA-templated transcription (inferred); PAR TICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH hepatocellular carcinoma (ortholog); FOUND IN NuA4 histone acetyltransferase complex (inferred); nucleoplasm (inferred); nucleus (inferred) | 14 | 59067282 | 59093399 | Dog | 24 | description | gene, protein-coding, MODEL [RefSeq] |
| 12547701 | Ing3 | inhibitor of growth family member 3 | ENCODES a protein that exhibits histone H2A acetyltransferase activity (inferred); histone H3K4me3 reader activity (inferred); histone H4 acetyltransferase activity (inferred); INVOLVED IN chromatin organization (inferred); chromatin remodeling (inferred); DNA-templated transcription (inferred); PAR TICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH hepatocellular carcinoma (ortholog); FOUND IN NuA4 histone acetyltransferase complex (inferred); nucleoplasm (inferred); nucleus (inferred) | NW_004936605 | 4154276 | 4179627 | Squirrel | 24 | description | gene, protein-coding, MODEL [RefSeq] |
| 14290667 | ING3 | inhibitor of growth family member 3 | ENCODES a protein that exhibits histone H2A acetyltransferase activity (inferred); histone H3K4me3 reader activity (inferred); histone H4 acetyltransferase activity (inferred); INVOLVED IN chromatin organization (inferred); chromatin remodeling (inferred); DNA-templated transcription (inferred); PAR TICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH hepatocellular carcinoma (ortholog); FOUND IN NuA4 histone acetyltransferase complex (inferred); nucleoplasm (inferred); nucleus (inferred); INTERACTS WITH deoxynivalenol | | | | Pig | 25 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 18682138 | ING3 | inhibitor of growth family member 3 | ENCODES a protein that exhibits histone H2A acetyltransferase activity (inferred); histone H3K4me3 reader activity (inferred); histone H4 acetyltransferase activity (inferred); INVOLVED IN chromatin organization (inferred); chromatin remodeling (inferred); DNA-templated transcription (inferred); PAR TICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH hepatocellular carcinoma (ortholog); FOUND IN NuA4 histone acetyltransferase complex (inferred); nucleoplasm (inferred); nucleus (inferred) | | | | Green Monkey | 25 | description | gene, protein-coding, MODEL [RefSeq] |
| 18904745 | Ing3 | inhibitor of growth family member 3 | ENCODES a protein that exhibits histone H2A acetyltransferase activity (ortholog); histone H3K4me3 reader activity (ortholog); histone H4 acetyltransferase activity (ortholog); INVOLVED IN positive regulation of double-strand break repair via homologous recombination (ortholog); regulation of cell c ycle (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH hepatocellular carcinoma (ortholog); FOUND IN nucleoplasm (ortholog); piccolo histone acetyltransferase complex (ortholog); Swr1 complex (ortholog) | | | | Naked Mole-Rat | 22 | description | gene, protein-coding, MODEL [RefSeq] |
| 625924483 | Ing3 | inhibitor of growth family member 3 | ENCODES a protein that exhibits histone H2A acetyltransferase activity (ortholog); histone H3K4me3 reader activity (ortholog); histone H4 acetyltransferase activity (ortholog); INVOLVED IN positive regulation of double-strand break repair via homologous recombination (ortholog); regulation of cell c ycle (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH hepatocellular carcinoma (ortholog); FOUND IN NuA4 histone acetyltransferase complex (ortholog); nucleoplasm (ortholog); piccolo histone acetyltransferase complex (ortholog) | | | | Black Rat | 17 | description | gene, protein-coding, MODEL [RefSeq] |
| 621061 | Kat5 | lysine acetyltransferase 5 | ENCODES a protein that exhibits chromatin binding; phospholipase binding; protein-containing complex binding; INVOLVED IN cellular response to hydrogen peroxide; cellular response to X-ray; positive regulation of transcription by RNA polymerase II; PARTICIPATES IN ataxia telangiectasia-mutated (ATM) signaling pathway; histone modification pathway; INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH iron deficiency anemia; B-cell lymphoma (ortholog); breast cancer (ortholog); FOUND IN chromatin; protein-containing complex; cytoplasm (ortholog); INTERACTS WITH 2,4-dinitrotoluene; 6-propyl-2-thiouracil; amitrole | 1 | 212325089 | 212332640 | Rat | 312 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 8768844 | Kat5 | lysine acetyltransferase 5 | ENCODES a protein that exhibits chromatin binding (ortholog); DNA-binding transcription factor binding (ortholog); histone acetyltransferase activity (ortholog); INVOLVED IN apoptotic process (ortholog); cellular response to estradiol stimulus (ortholog); cellular response to glucose starvation (ort holog); PARTICIPATES IN ataxia telangiectasia-mutated (ATM) signaling pathway; histone modification pathway; INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH B-cell lymphoma (ortholog); breast cancer (ortholog); iron deficiency anemia (ortholog); FOUND IN chromatin (ortholog); cytoplasm (ortholog); kinetochore (ortholog) | NW_004955422 | 19557498 | 19565044 | Chinchilla | 137 | description | gene, protein-coding, MODEL [RefSeq] |
| 12047555 | KAT5 | lysine acetyltransferase 5 | ENCODES a protein that exhibits chromatin binding (ortholog); phospholipase binding (ortholog); protein-containing complex binding (ortholog); INVOLVED IN cellular response to hydrogen peroxide (ortholog); cellular response to X-ray (ortholog); lipid droplet disassembly (ortholog); PARTICIPATES IN a taxia telangiectasia-mutated (ATM) signaling pathway; histone modification pathway; INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH B-cell lymphoma (ortholog); breast cancer (ortholog); iron deficiency anemia (ortholog); FOUND IN chromatin (ortholog); protein-containing complex (ortholog) | 11 | 61071118 | 61078667 | Bonobo | 157 | description | gene, protein-coding, MODEL [RefSeq] |
| 12397322 | KAT5 | lysine acetyltransferase 5 | ENCODES a protein that exhibits chromatin binding (ortholog); phospholipase binding (ortholog); protein-containing complex binding (ortholog); INVOLVED IN cellular response to hydrogen peroxide (ortholog); cellular response to X-ray (ortholog); lipid droplet disassembly (ortholog); PARTICIPATES IN a taxia telangiectasia-mutated (ATM) signaling pathway; histone modification pathway; INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH B-cell lymphoma (ortholog); breast cancer (ortholog); iron deficiency anemia (ortholog); FOUND IN chromatin (ortholog); protein-containing complex (ortholog) | 18 | 51499615 | 51507434 | Dog | 112 | description | gene, protein-coding, MODEL [RefSeq] |
| 12617579 | Kat5 | lysine acetyltransferase 5 | ENCODES a protein that exhibits chromatin binding (ortholog); phospholipase binding (ortholog); protein-containing complex binding (ortholog); INVOLVED IN cellular response to hydrogen peroxide (ortholog); cellular response to X-ray (ortholog); lipid droplet disassembly (ortholog); PARTICIPATES IN a taxia telangiectasia-mutated (ATM) signaling pathway; histone modification pathway; INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH B-cell lymphoma (ortholog); breast cancer (ortholog); iron deficiency anemia (ortholog); FOUND IN chromatin (ortholog); protein-containing complex (ortholog) | NW_004936599 | 3767526 | 3775416 | Squirrel | 154 | description | gene, protein-coding, MODEL [RefSeq] |
| 14001000 | KAT5 | lysine acetyltransferase 5 | ENCODES a protein that exhibits chromatin binding (ortholog); phospholipase binding (ortholog); protein-containing complex binding (ortholog); INVOLVED IN cellular response to hydrogen peroxide (ortholog); cellular response to X-ray (ortholog); lipid droplet disassembly (ortholog); PARTICIPATES IN a taxia telangiectasia-mutated (ATM) signaling pathway; histone modification pathway; INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH B-cell lymphoma (ortholog); breast cancer (ortholog); iron deficiency anemia (ortholog); FOUND IN chromatin (ortholog); protein-containing complex (ortholog) | | | | Pig | 154 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 18382479 | KAT5 | lysine acetyltransferase 5 | ENCODES a protein that exhibits chromatin binding (ortholog); phospholipase binding (ortholog); protein-containing complex binding (ortholog); INVOLVED IN cellular response to hydrogen peroxide (ortholog); cellular response to X-ray (ortholog); lipid droplet disassembly (ortholog); PARTICIPATES IN a taxia telangiectasia-mutated (ATM) signaling pathway; histone modification pathway; INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH B-cell lymphoma (ortholog); breast cancer (ortholog); iron deficiency anemia (ortholog); FOUND IN chromatin (ortholog); protein-containing complex (ortholog) | | | | Green Monkey | 155 | description | gene, protein-coding, MODEL [RefSeq] |
| 18923153 | Kat5 | lysine acetyltransferase 5 | ENCODES a protein that exhibits chromatin binding (ortholog); DNA-binding transcription factor binding (ortholog); histone H2A acetyltransferase activity (ortholog); INVOLVED IN apoptotic process (ortholog); cellular response to estradiol stimulus (ortholog); cellular response to glucose starvation (ortholog); PARTICIPATES IN ataxia telangiectasia-mutated (ATM) signaling pathway; histone modification pathway; INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH B-cell lymphoma (ortholog); breast cancer (ortholog); iron deficiency anemia (ortholog); FOUND IN chromatin (ortholog); cytoplasm (ortholog); mitotic spindle pole (ortholog) | | | | Naked Mole-Rat | 148 | description | gene, protein-coding, MODEL [RefSeq] |
| 626105566 | Kat5 | lysine acetyltransferase 5 | ENCODES a protein that exhibits chromatin binding (ortholog); DNA-binding transcription factor binding (ortholog); histone acetyltransferase activity (ortholog); INVOLVED IN apoptotic process (ortholog); cellular response to estradiol stimulus (ortholog); cellular response to glucose starvation (ort holog); PARTICIPATES IN ataxia telangiectasia-mutated (ATM) signaling pathway; histone modification pathway; INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH B-cell lymphoma (ortholog); breast cancer (ortholog); iron deficiency anemia (ortholog); FOUND IN chromatin (ortholog); cytoplasm (ortholog); kinetochore (ortholog) | | | | Black Rat | 137 | description | gene, protein-coding, MODEL [RefSeq] |
| 11986976 | LOC100971447 | E1A-binding protein p400 | ENCODES a protein that exhibits chromatin binding (ortholog); protein antigen binding (ortholog); INVOLVED IN gene expression (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH Neurodevelopmental Disorders (ortholog); FOUND IN nuclear speck (ortholog) | 12 | 129606823 | 129737179 | Bonobo | 32 | description | gene, protein-coding, MODEL [RefSeq] |
| 1311607 | Mcrs1 | microspherule protein 1 | ENCODES a protein that exhibits G-quadruplex RNA binding (ortholog); poly(G) binding (ortholog); poly(U) RNA binding (ortholog); INVOLVED IN chromatin remodeling (ortholog); negative regulation of telomere maintenance via telomere lengthening (ortholog); positive regulation of DNA repair (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN dendrite; perikaryon; cytoplasm (ortholog); INTERACTS WITH 2,4-dinitrotoluene; 4,4'-sulfonyldiphenol; bisphenol A | 7 | 132262719 | 132271533 | Rat | 134 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1323154 | Mcrs1 | microspherule protein 1 | Predicted to enable RNA binding activity and telomerase inhibitor activity. Involved in positive regulation of DNA metabolic process; regulation of embryonic development; and telomere maintenance. Predicted to be located in several cellular components, including dendrite; nuclear lumen; and perikary on. Predicted to be part of Ino80 complex; MLL1 complex; and NSL complex. Is expressed in several structures, including alimentary system; central nervous system; early conceptus; genitourinary system; and hemolymphoid system gland. Orthologous to human MCRS1 (microspherule protein 1). [provided by Alliance of Genome Resources, Jul 2025] | 15 | 99140698 | 99149838 | Mouse | 180 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 8707656 | Mcrs1 | microspherule protein 1 | ENCODES a protein that exhibits G-quadruplex RNA binding (ortholog); poly(G) binding (ortholog); poly(U) RNA binding (ortholog); INVOLVED IN chromatin remodeling (ortholog); negative regulation of telomere maintenance via telomere lengthening (ortholog); positive regulation of DNA repair (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN cytoplasm (ortholog); dendrite (ortholog); histone acetyltransferase complex (ortholog) | NW_004955547 | 180783 | 189980 | Chinchilla | 44 | description | gene, protein-coding, MODEL [RefSeq] |
| 11860099 | MCRS1 | microspherule protein 1 | ENCODES a protein that exhibits telomerase inhibitor activity (ortholog); INVOLVED IN negative regulation of telomere maintenance via telomere lengthening (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN dendrite (ortholog ); perikaryon (ortholog) | 12 | 39183112 | 39192925 | Bonobo | 61 | description | gene, protein-coding, MODEL [RefSeq] |
| 12083817 | MCRS1 | microspherule protein 1 | ENCODES a protein that exhibits telomerase inhibitor activity (ortholog); INVOLVED IN negative regulation of telomere maintenance via telomere lengthening (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN dendrite (ortholog ); perikaryon (ortholog) | 27 | 5076075 | 5085483 | Dog | 61 | description | gene, protein-coding, MODEL [RefSeq] |
| 12701795 | Mcrs1 | microspherule protein 1 | ENCODES a protein that exhibits telomerase inhibitor activity (ortholog); INVOLVED IN negative regulation of telomere maintenance via telomere lengthening (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN dendrite (ortholog ); perikaryon (ortholog) | NW_004936512 | 7277739 | 7287389 | Squirrel | 61 | description | gene, protein-coding, MODEL [RefSeq] |
| 14186462 | MCRS1 | microspherule protein 1 | ENCODES a protein that exhibits telomerase inhibitor activity (ortholog); INVOLVED IN negative regulation of telomere maintenance via telomere lengthening (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN dendrite (ortholog ); perikaryon (ortholog) | | | | Pig | 61 | description | gene, protein-coding, MODEL [RefSeq] |
| 18628840 | MCRS1 | microspherule protein 1 | ENCODES a protein that exhibits telomerase inhibitor activity (ortholog); INVOLVED IN negative regulation of telomere maintenance via telomere lengthening (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN dendrite (ortholog ); perikaryon (ortholog) | | | | Green Monkey | 61 | description | gene, protein-coding, MODEL [RefSeq] |
| 18907362 | Mcrs1 | microspherule protein 1 | ENCODES a protein that exhibits poly(G) binding (ortholog); poly(U) RNA binding (ortholog); telomerase inhibitor activity (ortholog); INVOLVED IN chromatin remodeling (ortholog); negative regulation of telomere maintenance via telomere lengthening (ortholog); positive regulation of DNA repair (ortho log); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN cytoplasm (ortholog); dendrite (ortholog); histone acetyltransferase complex (ortholog) | | | | Naked Mole-Rat | 57 | description | gene, protein-coding, MODEL [RefSeq] |
| 625866178 | Mcrs1 | microspherule protein 1 | ENCODES a protein that exhibits G-quadruplex RNA binding (ortholog); poly(G) binding (ortholog); poly(U) RNA binding (ortholog); INVOLVED IN chromatin remodeling (ortholog); negative regulation of telomere maintenance via telomere lengthening (ortholog); positive regulation of DNA repair (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN cytoplasm (ortholog); dendrite (ortholog); histone acetyltransferase complex (ortholog) | | | | Black Rat | 44 | description | gene, protein-coding, MODEL [RefSeq] |
| 1310440 | Meaf6 | MYST/Esa1-associated factor 6 | ENCODES a protein that exhibits histone H3K14 acetyltransferase activity (ortholog); histone H4K12 acetyltransferase activity (ortholog); histone H4K5 acetyltransferase activity (ortholog); INVOLVED IN positive regulation of double-strand break repair via homologous recombination (ortholog); regulat ion of cell cycle (ortholog); regulation of cell growth (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN kinetochore (ortholog); MOZ/MORF histone acetyltransferase complex (ortholog); NuA4 histone acetyltransferase complex (ortholog); INTERACTS WITH 4,4'-sulfonyldiphenol; acrylamide; bisphenol A | 5 | 142628281 | 142653076 | Rat | 76 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 8874483 | Meaf6 | MYST/Esa1 associated factor 6 | ENCODES a protein that exhibits histone H3K14 acetyltransferase activity (ortholog); histone H4K12 acetyltransferase activity (ortholog); histone H4K5 acetyltransferase activity (ortholog); INVOLVED IN positive regulation of double-strand break repair via homologous recombination (ortholog); regulat ion of cell cycle (ortholog); regulation of cell growth (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN kinetochore (ortholog); MOZ/MORF histone acetyltransferase complex (ortholog); NuA4 histone acetyltransferase complex (ortholog) | NW_004955452 | 15325227 | 15347175 | Chinchilla | 24 | description | gene, protein-coding, MODEL [RefSeq] |
| 11727694 | MEAF6 | MYST/Esa1 associated factor 6 | ENCODES a protein that exhibits histone H3K14 acetyltransferase activity (inferred); histone H4K12 acetyltransferase activity (inferred); histone H4K5 acetyltransferase activity (inferred); INVOLVED IN chromatin organization (inferred); chromatin remodeling (inferred); DNA-templated transcription (i nferred); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN histone acetyltransferase complex (inferred); kinetochore (inferred); MOZ/MORF histone acetyltransferase complex (inferred) | 1 | 36761402 | 36783746 | Bonobo | 34 | description | gene, protein-coding, MODEL [RefSeq] |
| 12255673 | MEAF6 | MYST/Esa1 associated factor 6 | ENCODES a protein that exhibits histone H3K14 acetyltransferase activity (inferred); histone H4K12 acetyltransferase activity (inferred); histone H4K5 acetyltransferase activity (inferred); INVOLVED IN chromatin organization (inferred); chromatin remodeling (inferred); DNA-templated transcription (i nferred); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN histone acetyltransferase complex (inferred); kinetochore (inferred); MOZ/MORF histone acetyltransferase complex (inferred) | 15 | 4944059 | 4971573 | Dog | 35 | description | gene, protein-coding, MODEL [RefSeq] |
| 12646093 | Meaf6 | MYST/Esa1 associated factor 6 | ENCODES a protein that exhibits histone H3K14 acetyltransferase activity (inferred); histone H4K12 acetyltransferase activity (inferred); histone H4K5 acetyltransferase activity (inferred); INVOLVED IN chromatin organization (inferred); chromatin remodeling (inferred); DNA-templated transcription (i nferred); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN histone acetyltransferase complex (inferred); kinetochore (inferred); MOZ/MORF histone acetyltransferase complex (inferred) | NW_004936474 | 19732278 | 19754228 | Squirrel | 34 | description | gene, protein-coding, MODEL [RefSeq] |
| 14029029 | MEAF6 | MYST/Esa1 associated factor 6 | ENCODES a protein that exhibits histone H3K14 acetyltransferase activity (inferred); histone H4K12 acetyltransferase activity (inferred); histone H4K5 acetyltransferase activity (inferred); INVOLVED IN chromatin organization (inferred); chromatin remodeling (inferred); DNA-templated transcription (i nferred); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN histone acetyltransferase complex (inferred); kinetochore (inferred); MOZ/MORF histone acetyltransferase complex (inferred) | | | | Pig | 34 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 18479987 | MEAF6 | MYST/Esa1 associated factor 6 | ENCODES a protein that exhibits histone H3K14 acetyltransferase activity (inferred); histone H4K12 acetyltransferase activity (inferred); histone H4K5 acetyltransferase activity (inferred); INVOLVED IN chromatin organization (inferred); chromatin remodeling (inferred); DNA-templated transcription (i nferred); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN histone acetyltransferase complex (inferred); kinetochore (inferred); MOZ/MORF histone acetyltransferase complex (inferred) | | | | Green Monkey | 34 | description | gene, protein-coding, MODEL [RefSeq] |
| 18921283 | Meaf6 | MYST/Esa1 associated factor 6 | ENCODES a protein that exhibits histone H3K14 acetyltransferase activity (ortholog); histone H4K12 acetyltransferase activity (ortholog); histone H4K5 acetyltransferase activity (ortholog); INVOLVED IN positive regulation of double-strand break repair via homologous recombination (ortholog); regulat ion of cell cycle (ortholog); regulation of cell growth (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN nucleoplasm (ortholog); nucleus (ortholog) | | | | Naked Mole-Rat | 30 | description | gene, protein-coding, MODEL [RefSeq] |
| 626052360 | Meaf6 | MYST/Esa1 associated factor 6 | ENCODES a protein that exhibits histone H3K14 acetyltransferase activity (ortholog); histone H4K12 acetyltransferase activity (ortholog); histone H4K5 acetyltransferase activity (ortholog); INVOLVED IN positive regulation of double-strand break repair via homologous recombination (ortholog); regulat ion of cell cycle (ortholog); regulation of cell growth (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN kinetochore (ortholog); MOZ/MORF histone acetyltransferase complex (ortholog); NuA4 histone acetyltransferase complex (ortholog) | | | | Black Rat | 24 | description | gene, protein-coding, MODEL [RefSeq] |
| 1307938 | Morf4l1 | mortality factor 4 like 1 | ENCODES a protein that exhibits chromatin binding (ortholog); INVOLVED IN cell population proliferation (ortholog); double-strand break repair via homologous recombination (ortholog); positive regulation of double-strand break repair via homologous recombination (ortholog); PARTICIPATES IN INO80 le='font-weight:700;'>INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH adenoid cystic carcinoma (ortholog); FOUND IN NuA4 histone acetyltransferase complex (ortholog); nuclear speck (ortholog); Sin3-type complex (ortholog); INTERACTS WITH 4,4'-sulfonyldiphenol; bisphenol A; bisphenol F | 8 | 99522801 | 99544432 | Rat | 85 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 8893006 | Morf4l1 | mortality factor 4 like 1 | ENCODES a protein that exhibits chromatin binding (ortholog); INVOLVED IN cell population proliferation (ortholog); double-strand break repair via homologous recombination (ortholog); positive regulation of double-strand break repair via homologous recombination (ortholog); PARTICIPATES IN INO80 le='font-weight:700;'>INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH adenoid cystic carcinoma (ortholog); FOUND IN NuA4 histone acetyltransferase complex (ortholog); nuclear speck (ortholog); Sin3-type complex (ortholog) | NW_004955533 | 14770 | 28290 | Chinchilla | 29 | description | gene, protein-coding, MODEL [RefSeq] |
| 11821015 | MORF4L1 | mortality factor 4 like 1 | ENCODES a protein that exhibits chromatin binding (ortholog); INVOLVED IN cell population proliferation (ortholog); double-strand break repair via homologous recombination (ortholog); regulation of cell cycle (ortholog); PARTICIPATES IN INO80 family mediated chr omatin remodeling pathway; ASSOCIATED WITH adenoid cystic carcinoma (ortholog); FOUND IN nuclear speck (ortholog); Sin3-type complex (ortholog) | 15 | 57844220 | 57869139 | Bonobo | 41 | description | gene, protein-coding, MODEL [RefSeq] |
| 12302353 | MORF4L1 | mortality factor 4 like 1 | ENCODES a protein that exhibits chromatin binding (inferred); INVOLVED IN cell population proliferation (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH adenoid cystic carcinoma (ortholog); FOUND IN NuA4 histone ace tyltransferase complex (inferred); nuclear speck (inferred); nucleus (inferred) | 3 | 58127152 | 58149709 | Dog | 39 | description | gene, protein-coding, MODEL [RefSeq] |
| 12734075 | Morf4l1 | mortality factor 4 like 1 | ENCODES a protein that exhibits chromatin binding (inferred); INVOLVED IN cell population proliferation (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH adenoid cystic carcinoma (ortholog); FOUND IN histone acetyltr ansferase complex (inferred); NuA4 histone acetyltransferase complex (inferred); nuclear speck (inferred) | NW_004936471 | 37073920 | 37097216 | Squirrel | 40 | description | gene, protein-coding, MODEL [RefSeq] |
| 13933820 | MORF4L1 | mortality factor 4 like 1 | ENCODES a protein that exhibits chromatin binding (inferred); INVOLVED IN cell population proliferation (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH adenoid cystic carcinoma (ortholog); FOUND IN NuA4 histone ace tyltransferase complex (inferred); nuclear speck (inferred); nucleus (inferred) | | | | Pig | 39 | description | gene, protein-coding, MODEL [RefSeq] |
| 18721055 | MORF4L1 | mortality factor 4 like 1 | ENCODES a protein that exhibits chromatin binding (ortholog); INVOLVED IN cell population proliferation (ortholog); double-strand break repair via homologous recombination (ortholog); positive regulation of double-strand break repair via homologous recombination (ortholog); PARTICIPATES IN INO80 le='font-weight:700;'>INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH adenoid cystic carcinoma (ortholog); FOUND IN NuA4 histone acetyltransferase complex (ortholog); nuclear speck (ortholog); Sin3-type complex (ortholog) | | | | Green Monkey | 29 | description | gene, protein-coding, MODEL [RefSeq] |
| 18906599 | Morf4l1 | mortality factor 4 like 1 | ENCODES a protein that exhibits chromatin binding (ortholog); INVOLVED IN cell population proliferation (ortholog); double-strand break repair via homologous recombination (ortholog); positive regulation of double-strand break repair via homologous recombination (ortholog); PARTICIPATES IN INO80 le='font-weight:700;'>INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH adenoid cystic carcinoma (ortholog); FOUND IN nuclear speck (ortholog); Sin3-type complex (ortholog) | | | | Naked Mole-Rat | 39 | description | gene, protein-coding, MODEL [RefSeq] |
| 626081284 | Morf4l1 | mortality factor 4 like 1 | ENCODES a protein that exhibits chromatin binding (ortholog); INVOLVED IN cell population proliferation (ortholog); double-strand break repair via homologous recombination (ortholog); positive regulation of double-strand break repair via homologous recombination (ortholog); PARTICIPATES IN INO80 le='font-weight:700;'>INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH adenoid cystic carcinoma (ortholog); FOUND IN NuA4 histone acetyltransferase complex (ortholog); nuclear speck (ortholog); Sin3-type complex (ortholog) | | | | Black Rat | 29 | description | gene, protein-coding, MODEL [RefSeq] |
| 1359471 | Morf4l2 | mortality factor 4 like 2 | INVOLVED IN positive regulation of striated muscle cell differentiation; positive regulation of transcription by RNA polymerase II; positive regulation of double-strand break repair via homologous recombination (ortholog); PARTICIPATES IN INO80 family mediated c hromatin remodeling pathway; FOUND IN nucleolus (ortholog); nucleoplasm (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | X | 104874850 | 104885946 | Rat | 118 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 9065462 | Morf4l2 | mortality factor 4 like 2 | INVOLVED IN positive regulation of double-strand break repair via homologous recombination (ortholog); positive regulation of striated muscle cell differentiation (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); PARTICIPATES IN INO80 pan> family mediated chromatin remodeling pathway; FOUND IN nucleolus (ortholog); nucleoplasm (ortholog) | NW_004955548 | 682409 | 685886 | Chinchilla | 18 | description | gene, protein-coding, MODEL [RefSeq] |
| 12045232 | MORF4L2 | mortality factor 4 like 2 | INVOLVED IN positive regulation of double-strand break repair via homologous recombination (ortholog); positive regulation of striated muscle cell differentiation (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); PARTICIPATES IN INO80 pan> family mediated chromatin remodeling pathway; FOUND IN nucleolus (ortholog); nucleoplasm (ortholog) | X | 92904721 | 92917340 | Bonobo | 18 | description | gene, protein-coding, MODEL [RefSeq] |
| 12189404 | MORF4L2 | mortality factor 4 like 2 | INVOLVED IN positive regulation of striated muscle cell differentiation (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN nucleolus (inferred); nucleopla sm (inferred); nucleus (inferred) | X | 77084940 | 77097900 | Dog | 27 | description | gene, protein-coding, MODEL [RefSeq] |
| 12505117 | Morf4l2 | mortality factor 4 like 2 | INVOLVED IN positive regulation of striated muscle cell differentiation (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN histone acetyltransferase compl ex (inferred); NuA4 histone acetyltransferase complex (inferred); nucleolus (inferred) | NW_004936499 | 10636711 | 10647442 | Squirrel | 28 | description | gene, protein-coding, MODEL [RefSeq] |
| 13917958 | MORF4L2 | mortality factor 4 like 2 | INVOLVED IN positive regulation of striated muscle cell differentiation (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN nucleolus (inferred); nucleopla sm (inferred); nucleus (inferred) | | | | Pig | 27 | description | gene, protein-coding, MODEL [RefSeq] |
| 18361099 | MORF4L2 | mortality factor 4 like 2 | INVOLVED IN positive regulation of striated muscle cell differentiation (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN histone acetyltransferase compl ex (inferred); NuA4 histone acetyltransferase complex (inferred); nucleolus (inferred) | | | | Green Monkey | 31 | description | gene, protein-coding, MODEL [RefSeq] |
| 18912973 | Morf4l2 | mortality factor 4 like 2 | INVOLVED IN positive regulation of double-strand break repair via homologous recombination (ortholog); positive regulation of striated muscle cell differentiation (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); PARTICIPATES IN INO80 pan> family mediated chromatin remodeling pathway; FOUND IN nucleolus (ortholog); nucleoplasm (ortholog) | | | | Naked Mole-Rat | 28 | description | gene, protein-coding, MODEL [RefSeq] |
| 626073197 | Morf4l2 | mortality factor 4 like 2 | INVOLVED IN positive regulation of double-strand break repair via homologous recombination (ortholog); positive regulation of striated muscle cell differentiation (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); PARTICIPATES IN INO80 pan> family mediated chromatin remodeling pathway; FOUND IN nucleolus (ortholog); nucleoplasm (ortholog) | | | | Black Rat | 18 | description | gene, protein-coding, MODEL [RefSeq] |
| 1308612 | Mrgbp | MRG domain binding protein | INVOLVED IN positive regulation of double-strand break repair via homologous recombination (ortholog); regulation of cell cycle (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH neuronal ceroid lipofuscinosis (orthol og); FOUND IN nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; azoxystrobin; bisphenol A | 3 | 188074695 | 188078162 | Rat | 60 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 8881044 | Mrgbp | MRG domain binding protein | INVOLVED IN positive regulation of double-strand break repair via homologous recombination (ortholog); regulation of cell cycle (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH neuronal ceroid lipofuscinosis (orthol og); FOUND IN nucleoplasm (ortholog) | NW_004955528 | 1320061 | 1324094 | Chinchilla | 12 | description | gene, protein-coding, MODEL [RefSeq] |
| 11717182 | MRGBP | MRG domain binding protein | INVOLVED IN positive regulation of double-strand break repair via homologous recombination (ortholog); regulation of cell cycle (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH neuronal ceroid lipofuscinosis (orthol og); FOUND IN nucleoplasm (ortholog) | 20 | 59183842 | 59187982 | Bonobo | 12 | description | gene, protein-coding, MODEL [RefSeq] |
| 12157113 | MRGBP | MRG domain binding protein | INVOLVED IN chromatin organization (inferred); DNA-templated transcription (inferred); positive regulation of double-strand break repair via homologous recombination (inferred); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH neuronal ceroid lipofuscinosis (ortholog); FOUND IN H4/H2A histone acetyltransferase complex (inferred); nucleoplasm (inferred); nucleus (inferred) | 24 | 46634580 | 46637222 | Dog | 20 | description | gene, protein-coding, MODEL [RefSeq] |
| 12532534 | Mrgbp | MRG domain binding protein | INVOLVED IN chromatin organization (inferred); DNA-templated transcription (inferred); positive regulation of double-strand break repair via homologous recombination (inferred); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH neuronal ceroid lipofuscinosis (ortholog); FOUND IN H4/H2A histone acetyltransferase complex (inferred); NuA4 histone acetyltransferase complex (inferred); nucleoplasm (inferred) | NW_004936514 | 10303870 | 10308007 | Squirrel | 20 | description | gene, protein-coding, MODEL [RefSeq] |
| 14062437 | MRGBP | MRG domain binding protein | INVOLVED IN chromatin organization (inferred); DNA-templated transcription (inferred); positive regulation of double-strand break repair via homologous recombination (inferred); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH neuronal ceroid lipofuscinosis (ortholog); FOUND IN H4/H2A histone acetyltransferase complex (inferred); nucleoplasm (inferred); nucleus (inferred) | | | | Pig | 20 | description | gene, protein-coding, MODEL [RefSeq] |
| 18384862 | MRGBP | MRG domain binding protein | INVOLVED IN chromatin organization (inferred); DNA-templated transcription (inferred); positive regulation of double-strand break repair via homologous recombination (inferred); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH neuronal ceroid lipofuscinosis (ortholog); FOUND IN H4/H2A histone acetyltransferase complex (inferred); NuA4 histone acetyltransferase complex (inferred); nucleoplasm (inferred) | | | | Green Monkey | 20 | description | gene, protein-coding, MODEL [RefSeq] |
| 18933245 | Mrgbp | MRG domain binding protein | INVOLVED IN positive regulation of double-strand break repair via homologous recombination (ortholog); regulation of cell cycle (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH neuronal ceroid lipofuscinosis (orthol og); FOUND IN nucleoplasm (ortholog) | | | | Naked Mole-Rat | 20 | description | gene, protein-coding, MODEL [RefSeq] |
| 626088985 | Mrgbp | MRG domain binding protein | INVOLVED IN positive regulation of double-strand break repair via homologous recombination (ortholog); regulation of cell cycle (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN nucleoplasm (ortholog) | | | | Black Rat | 11 | description | gene, protein-coding, MODEL [RefSeq] |
| 1614910 | Nfrkb | nuclear factor related to kappa B binding protein | Predicted to enable protease binding activity. Involved in positive regulation of DNA metabolic process; regulation of embryonic development; and telomere maintenance. Predicted to be located in nucleoplasm. Predicted to be part of Ino80 complex. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Orthologous to human NFRKB (nuclear factor related to kappaB binding protein). [provided by Alliance of Genome Resources, Jul 2025] | 9 | 31297476 | 31332629 | Mouse | 112 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 68373 | Ruvbl1 | RuvB-like AAA ATPase 1 | ENCODES a protein that exhibits 3'-5' DNA helicase activity; ADP binding (ortholog); ATP binding (ortholog); INVOLVED IN positive regulation of plasminogen activation; regulation of fibroblast apoptotic process; chromatin remodeling (ortholog); PARTICIPATES IN INO80 pan> family mediated chromatin remodeling pathway; Wnt signaling pathway; FOUND IN nuclear matrix; protein-containing complex; ciliary basal body (ortholog); INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine | 4 | 122489754 | 122524666 | Rat | 194 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 11960172 | RUVBL1 | RuvB like AAA ATPase 1 | ENCODES a protein that exhibits 3'-5' DNA helicase activity (ortholog); INVOLVED IN gene expression (ortholog); positive regulation of plasminogen activation (ortholog); regulation of fibroblast apoptotic process (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN nuclear matrix (ortholog); protein-containing complex (ortholog) | 3 | 125120524 | 125200859 | Bonobo | 76 | description | gene, protein-coding, MODEL [RefSeq] |
| 12434129 | RUVBL1 | RuvB like AAA ATPase 1 | ENCODES a protein that exhibits 3'-5' DNA helicase activity (ortholog); INVOLVED IN gene expression (ortholog); positive regulation of plasminogen activation (ortholog); regulation of fibroblast apoptotic process (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN nuclear matrix (ortholog); protein-containing complex (ortholog) | 20 | 2095807 | 2137528 | Dog | 73 | description | gene, protein-coding, MODEL [RefSeq] |
| 12438659 | Ruvbl1 | RuvB like AAA ATPase 1 | ENCODES a protein that exhibits 3'-5' DNA helicase activity (ortholog); INVOLVED IN gene expression (ortholog); positive regulation of plasminogen activation (ortholog); regulation of fibroblast apoptotic process (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN nuclear matrix (ortholog); protein-containing complex (ortholog) | NW_004936798 | 559706 | 572710 | Squirrel | 66 | description | gene, protein-coding, MODEL [RefSeq] |
| 14003960 | RUVBL1 | RuvB like AAA ATPase 1 | ENCODES a protein that exhibits 3'-5' DNA helicase activity (ortholog); INVOLVED IN gene expression (ortholog); positive regulation of plasminogen activation (ortholog); regulation of fibroblast apoptotic process (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN nuclear matrix (ortholog); protein-containing complex (ortholog) | | | | Pig | 74 | description | gene, protein-coding, MODEL [RefSeq] |
| 18349353 | RUVBL1 | RuvB like AAA ATPase 1 | ENCODES a protein that exhibits 3'-5' DNA helicase activity (ortholog); INVOLVED IN gene expression (ortholog); positive regulation of plasminogen activation (ortholog); regulation of fibroblast apoptotic process (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN nuclear matrix (ortholog); protein-containing complex (ortholog) | | | | Green Monkey | 75 | description | gene, protein-coding, MODEL [RefSeq] |
| 1306509 | Ruvbl2 | RuvB-like AAA ATPase 2 | ENCODES a protein that exhibits ADP binding (ortholog); ATP binding (ortholog); ATP hydrolysis activity (ortholog); INVOLVED IN cellular response to estradiol stimulus (ortholog); cellular response to UV (ortholog); chromatin remodeling (ortholog); PARTICIPATES IN INO80 0 family mediated chromatin remodeling pathway; FOUND IN cytoplasm (ortholog); cytosol (ortholog); euchromatin (ortholog); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 1 | 105038487 | 105051851 | Rat | 219 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 8956205 | Ruvbl2 | RuvB like AAA ATPase 2 | ENCODES a protein that exhibits ADP binding (ortholog); ATP binding (ortholog); ATP hydrolysis activity (ortholog); INVOLVED IN cellular response to estradiol stimulus (ortholog); cellular response to UV (ortholog); chromatin remodeling (ortholog); PARTICIPATES IN INO80 0 family mediated chromatin remodeling pathway; FOUND IN cytoplasm (ortholog); cytosol (ortholog); euchromatin (ortholog) | NW_004955559 | 1657241 | 1674272 | Chinchilla | 59 | description | gene, protein-coding, MODEL [RefSeq] |
| 11797306 | RUVBL2 | RuvB like AAA ATPase 2 | ENCODES a protein that exhibits ADP binding (ortholog); ATPase binding (ortholog); protein homodimerization activity (ortholog); INVOLVED IN gene expression (ortholog); positive regulation of DNA repair (ortholog); positive regulation of telomere maintenance in response to DNA damage (ortholog); PAR TICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN ribonucleoprotein complex (ortholog) | 19 | 45995394 | 46017835 | Bonobo | 83 | description | gene, protein-coding, MODEL [RefSeq] |
| 12175919 | RUVBL2 | RuvB like AAA ATPase 2 | ENCODES a protein that exhibits ADP binding (inferred); ATP binding (inferred); ATP hydrolysis activity (inferred); INVOLVED IN gene expression (ortholog); telomerase RNA localization to Cajal body (ortholog); PARTICIPATES IN INO80 family mediated chromatin remo deling pathway; FOUND IN cytoplasm (inferred); cytosol (inferred); dynein axonemal particle (inferred) | 1 | 107384328 | 107400849 | Dog | 82 | description | gene, protein-coding, MODEL [RefSeq] |
| 12559392 | Ruvbl2 | RuvB like AAA ATPase 2 | ENCODES a protein that exhibits ADP binding (inferred); ATP binding (inferred); ATP hydrolysis activity (inferred); INVOLVED IN gene expression (ortholog); telomerase RNA localization to Cajal body (ortholog); PARTICIPATES IN INO80 family mediated chromatin remo deling pathway; FOUND IN cytoplasm (inferred); cytosol (inferred); dynein axonemal particle (inferred) | NW_004936664 | 2995212 | 3010563 | Squirrel | 76 | description | gene, protein-coding, MODEL [RefSeq] |
| 14057153 | RUVBL2 | RuvB like AAA ATPase 2 | ENCODES a protein that exhibits ADP binding (inferred); ATP binding (inferred); ATP hydrolysis activity (inferred); INVOLVED IN gene expression (ortholog); telomerase RNA localization to Cajal body (ortholog); PARTICIPATES IN INO80 family mediated chromatin remo deling pathway; FOUND IN cytoplasm (inferred); cytosol (inferred); dynein axonemal particle (inferred); INTERACTS WITH deoxynivalenol | | | | Pig | 84 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 18726169 | RUVBL2 | RuvB like AAA ATPase 2 | ENCODES a protein that exhibits ADP binding (inferred); ATP binding (inferred); ATP hydrolysis activity (inferred); INVOLVED IN gene expression (ortholog); telomerase RNA localization to Cajal body (ortholog); PARTICIPATES IN INO80 family mediated chromatin remo deling pathway; FOUND IN cytoplasm (inferred); cytosol (inferred); dynein axonemal particle (inferred) | | | | Green Monkey | 82 | description | gene, protein-coding, MODEL [RefSeq] |
| 18903295 | Ruvbl2 | RuvB like AAA ATPase 2 | ENCODES a protein that exhibits ADP binding (ortholog); ATP hydrolysis activity (ortholog); ATPase binding (ortholog); INVOLVED IN cellular response to estradiol stimulus (ortholog); cellular response to UV (ortholog); chromatin remodeling (ortholog); PARTICIPATES IN INO80 NO80 family mediated chromatin remodeling pathway; FOUND IN cytoplasm (ortholog); cytosol (ortholog); euchromatin (ortholog) | | | | Naked Mole-Rat | 71 | description | gene, protein-coding, MODEL [RefSeq] |
| 625865859 | Ruvbl2 | RuvB like AAA ATPase 2 | ENCODES a protein that exhibits ADP binding (ortholog); ATP binding (ortholog); ATP hydrolysis activity (ortholog); INVOLVED IN cellular response to estradiol stimulus (ortholog); cellular response to UV (ortholog); chromatin remodeling (ortholog); PARTICIPATES IN INO80 0 family mediated chromatin remodeling pathway; FOUND IN cytoplasm (ortholog); cytosol (ortholog); euchromatin (ortholog) | | | | Black Rat | 59 | description | gene, protein-coding, MODEL [RefSeq] |
| 1565642 | Srcap | Snf2-related CREBBP activator protein | ENCODES a protein that exhibits ATP-dependent chromatin remodeler activity (ortholog); transcription coactivator activity (ortholog); INVOLVED IN cAMP/PKA signal transduction (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); PARTICIPATES IN INO80 0;'>INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH 46, XY Disorders of Sex Development (ortholog); adenoid cystic carcinoma (ortholog); autism spectrum disorder (ortholog); FOUND IN nuclear body (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 1 | 191554043 | 191607096 | Rat | 110 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 8807614 | Srcap | Snf2 related CREBBP activator protein | ENCODES a protein that exhibits ATP-dependent chromatin remodeler activity (ortholog); transcription coactivator activity (ortholog); INVOLVED IN cAMP/PKA signal transduction (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); PARTICIPATES IN INO80 0;'>INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH 46, XY Disorders of Sex Development (ortholog); adenoid cystic carcinoma (ortholog); autism spectrum disorder (ortholog); FOUND IN nuclear body (ortholog); nucleoplasm (ortholog); nucleus (ortholog) | NW_004955493 | 7554724 | 7602560 | Chinchilla | 29 | description | gene, protein-coding, MODEL [RefSeq] |
| 11755608 | SRCAP | Snf2 related CREBBP activator protein | ENCODES a protein that exhibits ATP-dependent chromatin remodeler activity (ortholog); INVOLVED IN cAMP/PKA signal transduction (inferred); chromatin organization (inferred); chromatin remodeling (inferred); PARTICIPATES IN INO80 family mediated chromatin remode ling pathway; ASSOCIATED WITH 46, XY Disorders of Sex Development (ortholog); adenoid cystic carcinoma (ortholog); autism spectrum disorder (ortholog); FOUND IN nucleus (ortholog) | 16 | 24229869 | 24271427 | Bonobo | 50 | description | gene, protein-coding, MODEL [RefSeq] |
| 12386809 | SRCAP | Snf2 related CREBBP activator protein | ENCODES a protein that exhibits ATP-dependent chromatin remodeler activity (ortholog); INVOLVED IN cAMP/PKA signal transduction (inferred); chromatin organization (inferred); chromatin remodeling (inferred); PARTICIPATES IN INO80 family mediated chromatin remode ling pathway; ASSOCIATED WITH 46, XY Disorders of Sex Development (ortholog); adenoid cystic carcinoma (ortholog); autism spectrum disorder (ortholog); FOUND IN nucleus (ortholog) | 6 | 17437097 | 17470724 | Dog | 50 | description | gene, protein-coding, MODEL [RefSeq] |
| 12503999 | Srcap | Snf2 related CREBBP activator protein | ENCODES a protein that exhibits ATP-dependent chromatin remodeler activity (ortholog); INVOLVED IN cAMP/PKA signal transduction (inferred); chromatin organization (inferred); chromatin remodeling (inferred); PARTICIPATES IN INO80 family mediated chromatin remode ling pathway; ASSOCIATED WITH 46, XY Disorders of Sex Development (ortholog); adenoid cystic carcinoma (ortholog); autism spectrum disorder (ortholog); FOUND IN nucleus (ortholog) | NW_004936501 | 13095690 | 13131183 | Squirrel | 49 | description | gene, protein-coding, MODEL [RefSeq] |
| 14048240 | SRCAP | Snf2 related CREBBP activator protein | ENCODES a protein that exhibits ATP-dependent chromatin remodeler activity (ortholog); INVOLVED IN cAMP/PKA signal transduction (inferred); chromatin organization (inferred); chromatin remodeling (inferred); PARTICIPATES IN INO80 family mediated chromatin remode ling pathway; ASSOCIATED WITH 46, XY Disorders of Sex Development (ortholog); adenoid cystic carcinoma (ortholog); autism spectrum disorder (ortholog); FOUND IN nucleus (ortholog) | | | | Pig | 49 | description | gene, protein-coding, MODEL [RefSeq] |
| 18360959 | SRCAP | Snf2 related CREBBP activator protein | ENCODES a protein that exhibits ATP-dependent chromatin remodeler activity (ortholog); INVOLVED IN cAMP/PKA signal transduction (inferred); chromatin organization (inferred); chromatin remodeling (inferred); PARTICIPATES IN INO80 family mediated chromatin remode ling pathway; ASSOCIATED WITH 46, XY Disorders of Sex Development (ortholog); adenoid cystic carcinoma (ortholog); autism spectrum disorder (ortholog); FOUND IN nucleus (ortholog) | | | | Green Monkey | 49 | description | gene, protein-coding, MODEL [RefSeq] |
| 18923946 | Srcap | Snf2 related CREBBP activator protein | ENCODES a protein that exhibits ATP-dependent chromatin remodeler activity (ortholog); transcription coactivator activity (ortholog); INVOLVED IN cAMP/PKA signal transduction (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); PARTICIPATES IN INO80 0;'>INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH 46, XY Disorders of Sex Development (ortholog); adenoid cystic carcinoma (ortholog); autism spectrum disorder (ortholog); FOUND IN nuclear body (ortholog); nucleus (ortholog); perinuclear region of cytoplasm (ortholog) | | | | Naked Mole-Rat | 45 | description | gene, protein-coding, MODEL [RefSeq] |
| 626140521 | Srcap | Snf2 related CREBBP activator protein | ENCODES a protein that exhibits ATP-dependent chromatin remodeler activity (ortholog); transcription coactivator activity (ortholog); INVOLVED IN cAMP/PKA signal transduction (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); PARTICIPATES IN INO80 0;'>INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH 46, XY Disorders of Sex Development (ortholog); adenoid cystic carcinoma (ortholog); autism spectrum disorder (ortholog); FOUND IN nuclear body (ortholog); nucleoplasm (ortholog); nucleus (ortholog) | | | | Black Rat | 29 | description | gene, protein-coding, MODEL [RefSeq] |
| 620839 | Tfpt | TCF3 fusion partner | ENCODES a protein that exhibits DNA binding; protein kinase binding; protein-containing complex binding; INVOLVED IN apoptotic process; male gonad development; positive regulation of apoptotic process; PARTICIPATES IN INO80 family mediated chromatin remodeling p athway; FOUND IN actin filament; cytoplasm; nucleus; INTERACTS WITH 2,4-dinitrotoluene; 2-methoxyethanol; 4,4'-sulfonyldiphenol | 1 | 74502994 | 74512766 | Rat | 106 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 733580 | Tfpt | TCF3 (E2A) fusion partner | Predicted to enable DNA binding activity and protein kinase binding activity. Involved in positive regulation of DNA metabolic process; regulation of embryonic development; and telomere maintenance. Predicted to be located in cytoplasm and nucleoplasm. Predicted to be part of Ino80 t:700;'>Ino80 complex. Predicted to colocalize with actin filament. Orthologous to human TFPT (TCF3 fusion partner). [provided by Alliance of Genome Resources, Jul 2025] | 7 | 3623323 | 3632911 | Mouse | 124 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 11716786 | TFPT | TCF3 fusion partner | ENCODES a protein that exhibits protein kinase binding (ortholog); protein-containing complex binding (ortholog); INVOLVED IN male gonad development (ortholog); positive regulation of apoptotic process (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN actin filament (ortholog); cytoplasm (ortholog) | 19 | 51039142 | 51048346 | Bonobo | 40 | description | gene, protein-coding, MODEL [RefSeq] |
| 12312628 | TFPT | TCF3 fusion partner | ENCODES a protein that exhibits protein kinase binding (ortholog); protein-containing complex binding (ortholog); INVOLVED IN male gonad development (ortholog); positive regulation of apoptotic process (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN actin filament (ortholog) | 1 | 103090723 | 103098601 | Dog | 50 | description | gene, protein-coding, MODEL [RefSeq] |
| 12587735 | Tfpt | TCF3 fusion partner | ENCODES a protein that exhibits protein kinase binding (ortholog); protein-containing complex binding (ortholog); INVOLVED IN male gonad development (ortholog); positive regulation of apoptotic process (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN actin filament (ortholog); cytoplasm (ortholog) | NW_004936994 | 234978 | 239425 | Squirrel | 40 | description | gene, protein-coding, MODEL [RefSeq] |
| 14164065 | TFPT | TCF3 fusion partner | ENCODES a protein that exhibits protein kinase binding (ortholog); protein-containing complex binding (ortholog); INVOLVED IN male gonad development (ortholog); positive regulation of apoptotic process (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN actin filament (ortholog); cytoplasm (ortholog); INTERACTS WITH deoxynivalenol | | | | Pig | 41 | description | gene, protein-coding, MODEL [RefSeq] |
| 18483894 | TFPT | TCF3 fusion partner | ENCODES a protein that exhibits protein kinase binding (ortholog); protein-containing complex binding (ortholog); INVOLVED IN male gonad development (ortholog); positive regulation of apoptotic process (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN actin filament (ortholog); cytoplasm (ortholog) | | | | Green Monkey | 40 | description | gene, protein-coding, MODEL [RefSeq] |
| 18929946 | Tfpt | TCF3 fusion partner | ENCODES a protein that exhibits protein kinase binding (ortholog); protein-containing complex binding (ortholog); INVOLVED IN chromatin remodeling (ortholog); male gonad development (ortholog); positive regulation of apoptotic process (ortholog); PARTICIPATES IN INO80 /span> family mediated chromatin remodeling pathway; FOUND IN actin filament (ortholog); cytoplasm (ortholog); nucleoplasm (ortholog) | | | | Naked Mole-Rat | 38 | description | gene, protein-coding, MODEL [RefSeq] |
| 1305446 | Trrap | transformation/transcription domain-associated protein | ENCODES a protein that exhibits chromatin binding; transcription coactivator activity (ortholog); transcription coregulator activity (ortholog); INVOLVED IN positive regulation of double-strand break repair via homologous recombination (ortholog); regulation of cell cycle (ortholog); regulation of D NA-templated transcription (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; RNA polymerase II transcription initiation pathway; ASSOCIATED WITH autosomal dominant nonsyndromic deafness 75 (ortholog); Developmental Delay with or without Dysmorphic Facies and Autism (ortholog); Developmental Disabilities (ortholog); FOUND IN NuA4 histone acetyltransferase complex (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH acrylamide; amphetamine; bisphenol A | 12 | 14851758 | 14941444 | Rat | 119 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 8887810 | Trrap | transformation/transcription domain associated protein | ENCODES a protein that exhibits chromatin binding (ortholog); transcription coactivator activity (ortholog); transcription coregulator activity (ortholog); INVOLVED IN positive regulation of double-strand break repair via homologous recombination (ortholog); regulation of cell cycle (ortholog); regu lation of DNA-templated transcription (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; RNA polymerase II transcription initiation pathway; ASSOCIATED WITH autosomal dominant nonsyndromic deafness 75 (ortholog); Developmental Delay with or without Dysmorphic Facies and Autism (ortholog); Developmental Disabilities (ortholog); FOUND IN NuA4 histone acetyltransferase complex (ortholog); nucleoplasm (ortholog); nucleus (ortholog) | NW_004955460 | 14641891 | 14761641 | Chinchilla | 34 | description | gene, protein-coding, MODEL [RefSeq] |
| 11810276 | TRRAP | transformation/transcription domain associated protein | ENCODES a protein that exhibits chromatin binding (ortholog); transcription coactivator activity (ortholog); transcription coregulator activity (ortholog); INVOLVED IN positive regulation of double-strand break repair via homologous recombination (ortholog); regulation of cell cycle (ortholog); regu lation of DNA-templated transcription (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; RNA polymerase II transcription initiation pathway; ASSOCIATED WITH autosomal dominant nonsyndromic deafness 75 (ortholog); Developmental Delay with or without Dysmorphic Facies and Autism (ortholog); Developmental Disabilities (ortholog); FOUND IN Swr1 complex (ortholog); transcription factor TFTC complex (ortholog); transcription regulator complex (ortholog) | 7 | 90845518 | 90981700 | Bonobo | 36 | description | gene, protein-coding, MODEL [RefSeq] |
| 12108323 | TRRAP | transformation/transcription domain associated protein | ENCODES a protein that exhibits chromatin binding (ortholog); transcription coactivator activity (ortholog); transcription coregulator activity (ortholog); INVOLVED IN positive regulation of double-strand break repair via homologous recombination (ortholog); regulation of cell cycle (ortholog); regu lation of DNA-templated transcription (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; RNA polymerase II transcription initiation pathway; ASSOCIATED WITH autosomal dominant nonsyndromic deafness 75 (ortholog); Developmental Delay with or without Dysmorphic Facies and Autism (ortholog); Developmental Disabilities (ortholog); FOUND IN nucleus (ortholog); Swr1 complex (ortholog); transcription factor TFTC complex (ortholog) | 6 | 10519734 | 10635175 | Dog | 36 | description | gene, protein-coding, MODEL [RefSeq] |
| 12641538 | Trrap | transformation/transcription domain associated protein | ENCODES a protein that exhibits chromatin binding (ortholog); transcription coactivator activity (ortholog); transcription coregulator activity (ortholog); INVOLVED IN positive regulation of double-strand break repair via homologous recombination (ortholog); regulation of cell cycle (ortholog); regu lation of DNA-templated transcription (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; RNA polymerase II transcription initiation pathway; ASSOCIATED WITH autosomal dominant nonsyndromic deafness 75 (ortholog); Developmental Delay with or without Dysmorphic Facies and Autism (ortholog); Developmental Disabilities (ortholog); FOUND IN Swr1 complex (ortholog); transcription factor TFTC complex (ortholog); transcription regulator complex (ortholog) | NW_004936750 | 1245926 | 1360226 | Squirrel | 35 | description | gene, protein-coding, MODEL [RefSeq] |
| 14069893 | TRRAP | transformation/transcription domain associated protein | ENCODES a protein that exhibits chromatin binding (ortholog); transcription coactivator activity (ortholog); transcription coregulator activity (ortholog); INVOLVED IN positive regulation of double-strand break repair via homologous recombination (ortholog); regulation of cell cycle (ortholog); regu lation of DNA-templated transcription (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; RNA polymerase II transcription initiation pathway; ASSOCIATED WITH autosomal dominant nonsyndromic deafness 75 (ortholog); Developmental Delay with or without Dysmorphic Facies and Autism (ortholog); Developmental Disabilities (ortholog); FOUND IN nucleus (ortholog); Swr1 complex (ortholog); transcription factor TFTC complex (ortholog) | | | | Pig | 36 | description | gene, protein-coding, MODEL [RefSeq] |
| 18342625 | TRRAP | transformation/transcription domain associated protein | ENCODES a protein that exhibits chromatin binding (ortholog); transcription coactivator activity (ortholog); transcription coregulator activity (ortholog); INVOLVED IN positive regulation of double-strand break repair via homologous recombination (ortholog); regulation of cell cycle (ortholog); regu lation of DNA-templated transcription (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; RNA polymerase II transcription initiation pathway; ASSOCIATED WITH autosomal dominant nonsyndromic deafness 75 (ortholog); Developmental Delay with or without Dysmorphic Facies and Autism (ortholog); Developmental Disabilities (ortholog); FOUND IN Swr1 complex (ortholog); transcription factor TFTC complex (ortholog); transcription regulator complex (ortholog) | | | | Green Monkey | 36 | description | gene, protein-coding, MODEL [RefSeq] |
| 18936577 | Trrap | transformation/transcription domain associated protein | ENCODES a protein that exhibits chromatin binding (ortholog); transcription coactivator activity (ortholog); transcription coregulator activity (ortholog); INVOLVED IN positive regulation of double-strand break repair via homologous recombination (ortholog); regulation of cell cycle (ortholog); regu lation of DNA-templated transcription (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; RNA polymerase II transcription initiation pathway; ASSOCIATED WITH autosomal dominant nonsyndromic deafness 75 (ortholog); Developmental Delay with or without Dysmorphic Facies and Autism (ortholog); Developmental Disabilities (ortholog); FOUND IN nucleoplasm (ortholog); Swr1 complex (ortholog); transcription factor TFTC complex (ortholog) | | | | Naked Mole-Rat | 35 | description | gene, protein-coding, MODEL [RefSeq] |
| 626006853 | Trrap | transformation/transcription domain associated protein | ENCODES a protein that exhibits chromatin binding (ortholog); transcription coactivator activity (ortholog); transcription coregulator activity (ortholog); INVOLVED IN positive regulation of double-strand break repair via homologous recombination (ortholog); regulation of cell cycle (ortholog); regu lation of DNA-templated transcription (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; RNA polymerase II transcription initiation pathway; ASSOCIATED WITH autosomal dominant nonsyndromic deafness 75 (ortholog); Developmental Delay with or without Dysmorphic Facies and Autism (ortholog); Developmental Disabilities (ortholog); FOUND IN NuA4 histone acetyltransferase complex (ortholog); nucleoplasm (ortholog); nucleus (ortholog) | | | | Black Rat | 33 | description | gene, protein-coding, MODEL [RefSeq] |
| 1305414 | Uchl5 | ubiquitin C-terminal hydrolase L5 | ENCODES a protein that exhibits cysteine-type deubiquitinase activity (ortholog); endopeptidase inhibitor activity (ortholog); proteasome binding (ortholog); INVOLVED IN regulation of AMPA receptor activity; chromatin remodeling (ortholog); forebrain morphogenesis (ortholog); PARTICIPATES IN INO80 tyle='font-weight:700;'>INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH alcohol-associated liver disease; Experimental Diabetes Mellitus; Testis Reperfusion Injury; FOUND IN cytosolic proteasome complex; synaptic vesicle; cytosol (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 3,3',4,4',5-pentachlorobiphenyl | 13 | 58070947 | 58106825 | Rat | 153 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1313433 | Uchl5 | ubiquitin carboxyl-terminal esterase L5 | Predicted to enable cysteine-type deubiquitinase activity; endopeptidase inhibitor activity; and proteasome binding activity. Involved in several processes, including brain development; positive regulation of DNA metabolic process; and telomere maintenance. Predicted to be located in cytosol; nucleo lus; and nucleoplasm. Predicted to be part of Ino80 complex and cytosolic proteasome complex. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; brain ventricular layer; genitourinary system; nose; and salivary gland primordium. Orthologous to human UCHL5 (ubiquitin C-terminal hydrolase L5). [provided by Alliance of Genome Resources, Jul 2025] | 1 | 143652993 | 143683204 | Mouse | 192 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 11904828 | UCHL5 | ubiquitin C-terminal hydrolase L5 | ENCODES a protein that exhibits cysteine-type deubiquitinase activity (inferred); cysteine-type peptidase activity (inferred); endopeptidase inhibitor activity (inferred); INVOLVED IN regulation of AMPA receptor activity (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH alcohol-associated liver disease (ortholog); Experimental Diabetes Mellitus (ortholog); Testis Reperfusion Injury (ortholog); FOUND IN cytosolic proteasome complex (ortholog); synaptic vesicle (ortholog) | 1 | 168471501 | 168519366 | Bonobo | 57 | description | gene, protein-coding, MODEL [RefSeq] |
| 12325188 | UCHL5 | ubiquitin C-terminal hydrolase L5 | ENCODES a protein that exhibits cysteine-type deubiquitinase activity (inferred); cysteine-type peptidase activity (inferred); endopeptidase inhibitor activity (inferred); INVOLVED IN regulation of AMPA receptor activity (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH alcohol-associated liver disease (ortholog); Experimental Diabetes Mellitus (ortholog); Testis Reperfusion Injury (ortholog); FOUND IN cytosolic proteasome complex (ortholog); synaptic vesicle (ortholog) | 38 | 6004595 | 6045999 | Dog | 57 | description | gene, protein-coding, MODEL [RefSeq] |
| 12461647 | Uchl5 | ubiquitin C-terminal hydrolase L5 | ENCODES a protein that exhibits cysteine-type deubiquitinase activity (inferred); cysteine-type peptidase activity (inferred); endopeptidase inhibitor activity (inferred); INVOLVED IN regulation of AMPA receptor activity (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH alcohol-associated liver disease (ortholog); Experimental Diabetes Mellitus (ortholog); Testis Reperfusion Injury (ortholog); FOUND IN cytosolic proteasome complex (ortholog); synaptic vesicle (ortholog) | NW_004936638 | 1242950 | 1289376 | Squirrel | 57 | description | gene, protein-coding, MODEL [RefSeq] |
| 18427650 | UCHL5 | ubiquitin C-terminal hydrolase L5 | ENCODES a protein that exhibits cysteine-type deubiquitinase activity (inferred); cysteine-type peptidase activity (inferred); endopeptidase inhibitor activity (inferred); INVOLVED IN regulation of AMPA receptor activity (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH alcohol-associated liver disease (ortholog); Experimental Diabetes Mellitus (ortholog); Testis Reperfusion Injury (ortholog); FOUND IN cytosolic proteasome complex (ortholog); synaptic vesicle (ortholog) | | | | Green Monkey | 57 | description | gene, protein-coding, MODEL [RefSeq] |
| 1306121 | Vps72 | vacuolar protein sorting 72 homolog | ENCODES a protein that exhibits histone binding (ortholog); histone chaperone activity (ortholog); INVOLVED IN positive regulation of double-strand break repair via homologous recombination (ortholog); regulation of cell cycle (ortholog); somatic stem cell population maintenance (ortholog); PARTICIP ATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN nuclear speck (ortholog); protein-containing complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 4,4'-sulfonyldiphenol | 2 | 185367329 | 185379199 | Rat | 82 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 8833427 | Vps72 | vacuolar protein sorting 72 homolog | ENCODES a protein that exhibits histone binding (ortholog); histone chaperone activity (ortholog); INVOLVED IN positive regulation of double-strand break repair via homologous recombination (ortholog); regulation of cell cycle (ortholog); somatic stem cell population maintenance (ortholog); PARTICIP ATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN nuclear speck (ortholog); protein-containing complex (ortholog) | NW_004955588 | 537122 | 550564 | Chinchilla | 14 | description | gene, protein-coding, MODEL [RefSeq] |
| 11902534 | VPS72 | vacuolar protein sorting 72 homolog | ENCODES a protein that exhibits histone binding (inferred); histone chaperone activity (inferred); INVOLVED IN somatic stem cell population maintenance (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN nuclear speck (inferr ed); nucleus (inferred); protein-containing complex (inferred) | 1 | 126525642 | 126539432 | Bonobo | 14 | description | gene, protein-coding, MODEL [RefSeq] |
| 12429933 | VPS72 | vacuolar protein sorting 72 homolog | ENCODES a protein that exhibits histone binding (inferred); histone chaperone activity (inferred); INVOLVED IN somatic stem cell population maintenance (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN nuclear speck (inferr ed); protein-containing complex (inferred) | 17 | 60239299 | 60252323 | Dog | 16 | description | gene, protein-coding, MODEL [RefSeq] |
| 12720904 | Vps72 | vacuolar protein sorting 72 homolog | ENCODES a protein that exhibits histone binding (inferred); histone chaperone activity (inferred); INVOLVED IN somatic stem cell population maintenance (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN nuclear speck (inferr ed); nucleus (inferred); protein-containing complex (inferred) | NW_004936580 | 1381454 | 1395319 | Squirrel | 14 | description | gene, protein-coding, MODEL [RefSeq] |
| 14020915 | VPS72 | vacuolar protein sorting 72 homolog | ENCODES a protein that exhibits histone binding (inferred); histone chaperone activity (inferred); INVOLVED IN somatic stem cell population maintenance (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN nuclear speck (inferr ed); protein-containing complex (inferred); INTERACTS WITH deoxynivalenol | | | | Pig | 17 | description | gene, protein-coding, MODEL [RefSeq] |
| 18634734 | VPS72 | vacuolar protein sorting 72 homolog | ENCODES a protein that exhibits histone binding (inferred); histone chaperone activity (inferred); INVOLVED IN somatic stem cell population maintenance (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN nuclear speck (inferr ed); nucleus (inferred); protein-containing complex (inferred) | | | | Green Monkey | 14 | description | gene, protein-coding, MODEL [RefSeq] |
| 18902602 | Vps72 | vacuolar protein sorting 72 homolog | ENCODES a protein that exhibits histone binding (ortholog); histone chaperone activity (ortholog); INVOLVED IN positive regulation of double-strand break repair via homologous recombination (ortholog); regulation of cell cycle (ortholog); somatic stem cell population maintenance (ortholog); PARTICIP ATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN nuclear speck (ortholog); protein-containing complex (ortholog) | | | | Naked Mole-Rat | 15 | description | gene, protein-coding, MODEL [RefSeq] |
| 625960426 | Vps72 | vacuolar protein sorting 72 homolog | ENCODES a protein that exhibits histone binding (ortholog); histone chaperone activity (ortholog); INVOLVED IN positive regulation of double-strand break repair via homologous recombination (ortholog); regulation of cell cycle (ortholog); somatic stem cell population maintenance (ortholog); PARTICIP ATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN nuclear speck (ortholog); protein-containing complex (ortholog) | | | | Black Rat | 14 | description | gene, protein-coding, MODEL [RefSeq] |
| 1312705 | WBP1 | WW domain binding protein 1 | The globular WW domain, named for the conserved tryptophan residues in the protein motif present in various structural and regulatory proteins, is known to play a role in the mediation of protein-protein interactions. This gene encodes a ligand of the WW domain of the Yes kinase-associated protein. Readthrough transcription of the neighboring upstream gene, which encodes INO80 complex subunit B, into this gene generates a non-coding transcript. [provided by RefSeq, Feb 2011] | 2 | 74458438 | 74460881 | Human | 73 | description | gene, protein-coding, REVIEWED [RefSeq] |
| 1305741 | Yeats4 | YEATS domain containing 4 | ENCODES a protein that exhibits histone H3K18ac reader activity (ortholog); histone H3K27ac reader activity (ortholog); INVOLVED IN gene expression (ortholog); positive regulation of double-strand break repair via homologous recombination (ortholog); regulation of cell cycle (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH high grade glioma; liposarcoma (ortholog); FOUND IN NuA4 histone acetyltransferase complex (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; acrylamide | 7 | 54744220 | 54751361 | Rat | 83 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 8843480 | Yeats4 | YEATS domain containing 4 | ENCODES a protein that exhibits histone H3K18ac reader activity (ortholog); histone H3K27ac reader activity (ortholog); INVOLVED IN gene expression (ortholog); positive regulation of double-strand break repair via homologous recombination (ortholog); regulation of cell cycle (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH high grade glioma (ortholog); liposarcoma (ortholog); FOUND IN NuA4 histone acetyltransferase complex (ortholog); nucleoplasm (ortholog); nucleus (ortholog) | NW_004955405 | 9677701 | 9706541 | Chinchilla | 17 | description | gene, protein-coding, MODEL [RefSeq] |
| 12041554 | YEATS4 | YEATS domain containing 4 | ENCODES a protein that exhibits histone H3K18ac reader activity (inferred); histone H3K27ac reader activity (inferred); INVOLVED IN gene expression (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH high grade glioma (ortholog); liposarcoma (ortholog); FOUND IN NuA4 histone acetyltransferase complex (inferred); nucleoplasm (inferred); nucleus (inferred) | 12 | 66881733 | 66912966 | Bonobo | 23 | description | gene, protein-coding, MODEL [RefSeq] |
| 12334230 | YEATS4 | YEATS domain containing 4 | ENCODES a protein that exhibits histone H3K18ac reader activity (inferred); histone H3K27ac reader activity (inferred); INVOLVED IN gene expression (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH high grade glioma (ortholog); liposarcoma (ortholog); FOUND IN NuA4 histone acetyltransferase complex (inferred); nucleoplasm (inferred); nucleus (inferred) | 10 | 11364435 | 11382340 | Dog | 28 | description | gene, protein-coding, MODEL [RefSeq] |
| 12437330 | Yeats4 | YEATS domain containing 4 | ENCODES a protein that exhibits histone H3K18ac reader activity (inferred); histone H3K27ac reader activity (inferred); INVOLVED IN gene expression (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH high grade glioma (ortholog); liposarcoma (ortholog); FOUND IN NuA4 histone acetyltransferase complex (inferred); nucleoplasm (inferred); nucleus (inferred) | NW_004936545 | 7179806 | 7205600 | Squirrel | 22 | description | gene, protein-coding, MODEL [RefSeq] |
| 13853521 | YEATS4 | YEATS domain containing 4 | ENCODES a protein that exhibits histone H3K18ac reader activity (inferred); histone H3K27ac reader activity (inferred); INVOLVED IN gene expression (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH high grade glioma (ortholog); liposarcoma (ortholog); FOUND IN NuA4 histone acetyltransferase complex (inferred); nucleoplasm (inferred); nucleus (inferred) | | | | Pig | 23 | description | gene, protein-coding, MODEL [RefSeq] |
| 18764576 | YEATS4 | YEATS domain containing 4 | ENCODES a protein that exhibits histone H3K18ac reader activity (inferred); histone H3K27ac reader activity (inferred); INVOLVED IN gene expression (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH high grade glioma (ortholog); liposarcoma (ortholog); FOUND IN NuA4 histone acetyltransferase complex (inferred); nucleoplasm (inferred); nucleus (inferred) | | | | Green Monkey | 22 | description | gene, protein-coding, MODEL [RefSeq] |
| 18911411 | Yeats4 | YEATS domain containing 4 | ENCODES a protein that exhibits histone H3K18ac reader activity (ortholog); histone H3K27ac reader activity (ortholog); INVOLVED IN gene expression (ortholog); positive regulation of double-strand break repair via homologous recombination (ortholog); regulation of cell cycle (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH high grade glioma (ortholog); liposarcoma (ortholog); FOUND IN NuA4 histone acetyltransferase complex (ortholog) | | | | Naked Mole-Rat | 21 | description | gene, protein-coding, MODEL [RefSeq] |
| 626068568 | Yeats4 | YEATS domain containing 4 | ENCODES a protein that exhibits histone H3K18ac reader activity (ortholog); histone H3K27ac reader activity (ortholog); INVOLVED IN gene expression (ortholog); positive regulation of double-strand break repair via homologous recombination (ortholog); regulation of cell cycle (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH high grade glioma (ortholog); liposarcoma (ortholog); FOUND IN NuA4 histone acetyltransferase complex (ortholog); nucleoplasm (ortholog); nucleus (ortholog) | | | | Black Rat | 17 | description | gene, protein-coding, MODEL [RefSeq] |
| 3982 | Yy1 | YY1 transcription factor | ENCODES a protein that exhibits sequence-specific DNA binding; chromatin binding (ortholog); cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN cellular response to interleukin-1; negative regulation of cell growth involved in cardiac muscle cell development; negative regula tion of transcription by RNA polymerase II; PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; mTOR signaling pathway; Notch signaling pathway; ASSOCIATED WITH Cardiomegaly; Neointima; type 1 diabetes mellitus; FOUND IN nuclear matrix; transcription regulator complex; chromatin (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 2,4-dinitrotoluene | 6 | 133471615 | 133500875 | Rat | 331 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 8929586 | Yy1 | YY1 transcription factor | ENCODES a protein that exhibits chromatin binding (ortholog); cis-regulatory region sequence-specific DNA binding (ortholog); DNA binding (ortholog); INVOLVED IN anterior/posterior pattern specification (ortholog); B cell differentiation (ortholog); camera-type eye morphogenesis (ortholog); PARTICIP ATES IN INO80 family mediated chromatin remodeling pathway; mTOR signaling pathway; Notch signaling pathway; ASSOCIATED WITH Cardiomegaly (ortholog); congestive heart failure (ortholog); developmental and epileptic encephalopathy 78 (ortholog); FOUND IN chromatin (ortholog); chromatin silencing complex (ortholog); fibrillar center (ortholog) | NW_004955438 | 21341374 | 21377674 | Chinchilla | 129 | description | gene, protein-coding, MODEL [RefSeq] |
| 11913701 | YY1 | YY1 transcription factor | ENCODES a protein that exhibits chromatin binding (ortholog); cis-regulatory region sequence-specific DNA binding (ortholog); DNA binding (ortholog); INVOLVED IN anterior/posterior pattern specification (ortholog); B cell differentiation (ortholog); camera-type eye morphogenesis (ortholog); PARTICIP ATES IN INO80 family mediated chromatin remodeling pathway; mTOR signaling pathway; Notch signaling pathway; ASSOCIATED WITH Cardiomegaly (ortholog); congestive heart failure (ortholog); developmental and epileptic encephalopathy 78 (ortholog); FOUND IN chromatin (ortholog); chromatin silencing complex (ortholog); fibrillar center (ortholog) | 14 | 80859491 | 80903651 | Bonobo | 129 | description | gene, protein-coding, MODEL [RefSeq] |
| 12360152 | YY1 | YY1 transcription factor | ENCODES a protein that exhibits sequence-specific DNA binding (ortholog); INVOLVED IN anterior/posterior pattern specification (ortholog); camera-type eye morphogenesis (ortholog); cellular response to interleukin-1 (ortholog); PARTICIPATES IN INO80 family media ted chromatin remodeling pathway; mTOR signaling pathway; Notch signaling pathway; ASSOCIATED WITH Cardiomegaly (ortholog); congestive heart failure (ortholog); developmental and epileptic encephalopathy 78 (ortholog); FOUND IN nuclear matrix (ortholog); nucleus (ortholog); ribonucleoprotein complex (ortholog) | 8 | 68539511 | 68572796 | Dog | 134 | description | gene, protein-coding, MODEL [RefSeq] |
| 12686884 | Yy1 | YY1 transcription factor | ENCODES a protein that exhibits chromatin binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription factor activity (ortholog); INVOLVED IN anterior/posterior pattern specification (ortholog); B cell differentiation (ortholog); camera-type eye morphogenesis (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; mTOR signaling pathway; Notch signaling pathway; ASSOCIATED WITH Cardiomegaly (ortholog); congestive heart failure (ortholog); developmental and epileptic encephalopathy 78 (ortholog); FOUND IN chromatin (ortholog); chromatin silencing complex (ortholog); fibrillar center (ortholog) | NW_004936604 | 3911407 | 3945405 | Squirrel | 129 | description | gene, protein-coding, MODEL [RefSeq] |
| 14090664 | YY1 | YY1 transcription factor | ENCODES a protein that exhibits sequence-specific DNA binding (ortholog); INVOLVED IN anterior/posterior pattern specification (ortholog); camera-type eye morphogenesis (ortholog); cellular response to interleukin-1 (ortholog); PARTICIPATES IN INO80 family media ted chromatin remodeling pathway; mTOR signaling pathway; Notch signaling pathway; ASSOCIATED WITH Cardiomegaly (ortholog); congestive heart failure (ortholog); developmental and epileptic encephalopathy 78 (ortholog); FOUND IN nuclear matrix (ortholog); nucleus (ortholog); ribonucleoprotein complex (ortholog) | | | | Pig | 134 | description | gene, protein-coding, MODEL [RefSeq] |
| 18425452 | YY1 | YY1 transcription factor | ENCODES a protein that exhibits sequence-specific DNA binding (ortholog); INVOLVED IN anterior/posterior pattern specification (ortholog); camera-type eye morphogenesis (ortholog); cellular response to interleukin-1 (ortholog); PARTICIPATES IN INO80 family media ted chromatin remodeling pathway; mTOR signaling pathway; Notch signaling pathway; ASSOCIATED WITH Cardiomegaly (ortholog); congestive heart failure (ortholog); developmental and epileptic encephalopathy 78 (ortholog); FOUND IN chromatin (ortholog); nuclear matrix (ortholog); nucleus (ortholog) | | | | Green Monkey | 134 | description | gene, protein-coding, MODEL [RefSeq] |
| 18930495 | Yy1 | YY1 transcription factor | ENCODES a protein that exhibits chromatin binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription factor activity (ortholog); INVOLVED IN anterior/posterior pattern specification (ortholog); B cell differentiation (ortholog); camera-type eye morphogenesis (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; mTOR signaling pathway; Notch signaling pathway; ASSOCIATED WITH Cardiomegaly (ortholog); congestive heart failure (ortholog); developmental and epileptic encephalopathy 78 (ortholog); FOUND IN chromatin (ortholog); chromatin silencing complex (ortholog); fibrillar center (ortholog) | | | | Naked Mole-Rat | 128 | description | gene, protein-coding, MODEL [RefSeq] |
| 626020752 | Yy1 | YY1 transcription factor | ENCODES a protein that exhibits chromatin binding (ortholog); cis-regulatory region sequence-specific DNA binding (ortholog); DNA binding (ortholog); INVOLVED IN anterior/posterior pattern specification (ortholog); B cell differentiation (ortholog); camera-type eye morphogenesis (ortholog); PARTICIP ATES IN INO80 family mediated chromatin remodeling pathway; mTOR signaling pathway; Notch signaling pathway; ASSOCIATED WITH Cardiomegaly (ortholog); congestive heart failure (ortholog); developmental and epileptic encephalopathy 78 (ortholog); FOUND IN chromatin (ortholog); chromatin silencing complex (ortholog); fibrillar center (ortholog) | | | | Black Rat | 129 | description | gene, protein-coding, MODEL [RefSeq] |
| 1605369 | YY1AP1 | YY1 associated protein 1 | Involved in cell differentiation; cell population proliferation; and regulation of cell cycle. Located in Ino80 complex; fibrillar center; and nucleoplasm. [provided by Alliance of Genome Resources, Jul 2025] | 1 | 155659442 | 155688996 | Human | 144 | description | gene, protein-coding, REVIEWED [RefSeq] |
| 11790110 | YY1AP1 | YY1 associated protein 1 | ENCODES a protein that exhibits transcription coregulator activity (inferred); INVOLVED IN cell differentiation (inferred); cell population proliferation (inferred); DNA-templated transcription (inferred); ASSOCIATED WITH genetic disease (ortholog); Grange Syndrome (ortholog); intellectual disabilit y (ortholog); FOUND IN Ino80 complex (inferred); nucleolus (inferred); nucleoplasm (inferred) | 1 | 130995949 | 131024985 | Bonobo | 21 | description | gene, protein-coding, MODEL [RefSeq] |
| 40894083 | YY1AP1 | YY1 associated protein 1 | ENCODES a protein that exhibits transcription coregulator activity (inferred); INVOLVED IN cell differentiation (inferred); cell population proliferation (inferred); DNA-templated transcription (inferred); ASSOCIATED WITH genetic disease (ortholog); Grange Syndrome (ortholog); intellectual disabilit y (ortholog); FOUND IN Ino80 complex (inferred); nucleolus (inferred); nucleoplasm (inferred) | | | | Green Monkey | 21 | description | gene, protein-coding, MODEL [RefSeq] |
| 2322870 | Znhit1 | zinc finger, HIT-type containing 1 | ENCODES a protein that exhibits chromatin binding (ortholog); histone binding (ortholog); histone deacetylase binding (ortholog); INVOLVED IN calcium ion homeostasis (ortholog); chromatin remodeling (ortholog); heart process (ortholog); PARTICIPATES IN INO80 fam ily mediated chromatin remodeling pathway; p53 signaling pathway; FOUND IN nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrotoluene; 2,4-dinitrotoluene | 12 | 25323292 | 25329566 | Rat | 98 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 8780352 | Znhit1 | zinc finger HIT-type containing 1 | ENCODES a protein that exhibits chromatin binding (ortholog); histone binding (ortholog); histone deacetylase binding (ortholog); INVOLVED IN calcium ion homeostasis (ortholog); chromatin remodeling (ortholog); heart process (ortholog); PARTICIPATES IN INO80 fam ily mediated chromatin remodeling pathway; p53 signaling pathway; FOUND IN nucleus (ortholog) | NW_004955456 | 16070622 | 16082286 | Chinchilla | 31 | description | gene, protein-coding, MODEL [RefSeq] |
| 11981254 | ZNHIT1 | zinc finger HIT-type containing 1 | ENCODES a protein that exhibits chromatin binding (inferred); histone binding (inferred); histone deacetylase binding (inferred); INVOLVED IN negative regulation of G0 to G1 transition (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); regulation of T cell proliferatio n (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; p53 signaling pathway; FOUND IN nucleus (inferred) | 7 | 93359038 | 93365521 | Bonobo | 35 | description | gene, protein-coding, MODEL [RefSeq] |
| 12238103 | ZNHIT1 | zinc finger HIT-type containing 1 | ENCODES a protein that exhibits chromatin binding (inferred); histone binding (inferred); histone deacetylase binding (inferred); INVOLVED IN negative regulation of G0 to G1 transition (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); regulation of T cell proliferatio n (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; p53 signaling pathway; FOUND IN nucleus (inferred) | 6 | 8658288 | 8663511 | Dog | 37 | description | gene, protein-coding, MODEL [RefSeq] |
| 12729077 | Znhit1 | zinc finger HIT-type containing 1 | ENCODES a protein that exhibits chromatin binding (inferred); histone binding (inferred); histone deacetylase binding (inferred); INVOLVED IN negative regulation of G0 to G1 transition (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); regulation of T cell proliferatio n (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; p53 signaling pathway; FOUND IN nucleus (inferred) | NW_004936543 | 1098095 | 1104731 | Squirrel | 35 | description | gene, protein-coding, MODEL [RefSeq] |
| 13943906 | ZNHIT1 | zinc finger HIT-type containing 1 | ENCODES a protein that exhibits chromatin binding (inferred); histone binding (inferred); histone deacetylase binding (inferred); INVOLVED IN negative regulation of G0 to G1 transition (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); regulation of T cell proliferatio n (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; p53 signaling pathway; FOUND IN nucleus (inferred) | | | | Pig | 37 | description | gene, protein-coding, MODEL [RefSeq] |
| 18504653 | ZNHIT1 | zinc finger HIT-type containing 1 | ENCODES a protein that exhibits chromatin binding (inferred); histone binding (inferred); histone deacetylase binding (inferred); INVOLVED IN negative regulation of G0 to G1 transition (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); regulation of T cell proliferatio n (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; p53 signaling pathway; FOUND IN nucleus (inferred) | | | | Green Monkey | 35 | description | gene, protein-coding, MODEL [RefSeq] |
| 18916701 | Znhit1 | zinc finger HIT-type containing 1 | ENCODES a protein that exhibits histone binding (ortholog); INVOLVED IN muscle cell differentiation (ortholog); negative regulation of G0 to G1 transition (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); PARTICIPATES IN INO80 fam ily mediated chromatin remodeling pathway; p53 signaling pathway; FOUND IN nucleus (inferred) | | | | Naked Mole-Rat | 35 | description | gene, protein-coding, MODEL [RefSeq] |
| 626152232 | Znhit1 | zinc finger HIT-type containing 1 | ENCODES a protein that exhibits chromatin binding (ortholog); histone binding (ortholog); histone deacetylase binding (ortholog); INVOLVED IN calcium ion homeostasis (ortholog); chromatin remodeling (ortholog); heart process (ortholog); PARTICIPATES IN INO80 fam ily mediated chromatin remodeling pathway; p53 signaling pathway; FOUND IN nucleus (ortholog) | | | | Black Rat | 31 | description | gene, protein-coding, MODEL [RefSeq] |
| 16553243 | AC007679.1 | novel transcript, antisense to INO80D | | | | | Human | | name | gene, lncrna |
