ACTR5 (actin related protein 5) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: ACTR5 (actin related protein 5) Homo sapiens
Analyze
Symbol: ACTR5
Name: actin related protein 5
RGD ID: 1317453
HGNC Page HGNC:14671
Description: Involved in several processes, including DNA repair; chromatin remodeling; and regulation of nucleobase-containing compound metabolic process. Located in Ino80 complex and cytoplasm.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: actin-related protein 5; Arp5; ARP5 actin related protein 5 homolog; ARP5 actin-related protein 5 homolog; ARP5 actin-related protein 5 homolog (yeast); FLJ12785; hARP5; INO80 complex subunit M; INO80M; sarcoma antigen NY-SAR-16
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382038,748,460 - 38,772,520 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2038,748,460 - 38,772,520 (+)EnsemblGRCh38hg38GRCh38
GRCh372037,377,103 - 37,401,163 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362036,810,511 - 36,834,503 (+)NCBINCBI36Build 36hg18NCBI36
Build 342036,810,510 - 36,834,247NCBI
Celera2034,087,821 - 34,111,793 (+)NCBICelera
Cytogenetic Map20q11.23NCBI
HuRef2034,114,312 - 34,138,221 (+)NCBIHuRef
CHM1_12037,281,298 - 37,305,288 (+)NCBICHM1_1
T2T-CHM13v2.02040,478,618 - 40,502,676 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA,IDA,IEA)
Ino80 complex  (IBA,IDA)
nucleoplasm  (TAS)
nucleus  (IDA,IEA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
2. The INO80 family of chromatin-remodeling enzymes: regulators of histone variant dynamics. Watanabe S and Peterson CL, Cold Spring Harb Symp Quant Biol. 2010;75:35-42. doi: 10.1101/sqb.2010.75.063. Epub 2011 Apr 18.
Additional References at PubMed
PMID:11780052   PMID:12477932   PMID:12601173   PMID:14702039   PMID:15489334   PMID:16230350   PMID:17643375   PMID:17721549   PMID:18026119   PMID:18163988   PMID:18922472   PMID:19014934  
PMID:20197409   PMID:20855601   PMID:21303910   PMID:21873635   PMID:21900206   PMID:22939629   PMID:24104479   PMID:24163370   PMID:24567363   PMID:25016522   PMID:25056061   PMID:26186194  
PMID:26340092   PMID:26344197   PMID:26354767   PMID:26496610   PMID:26949251   PMID:27248496   PMID:27641337   PMID:27705803   PMID:28514442   PMID:28515276   PMID:28533407   PMID:28561026  
PMID:29509190   PMID:29643506   PMID:30554943   PMID:30804502   PMID:31527615   PMID:31753913   PMID:32296183   PMID:33660365   PMID:33961781   PMID:35140242   PMID:35256949   PMID:35271311  
PMID:35559673   PMID:35831314   PMID:37689310  


Genomics

Comparative Map Data
ACTR5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382038,748,460 - 38,772,520 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2038,748,460 - 38,772,520 (+)EnsemblGRCh38hg38GRCh38
GRCh372037,377,103 - 37,401,163 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362036,810,511 - 36,834,503 (+)NCBINCBI36Build 36hg18NCBI36
Build 342036,810,510 - 36,834,247NCBI
Celera2034,087,821 - 34,111,793 (+)NCBICelera
Cytogenetic Map20q11.23NCBI
HuRef2034,114,312 - 34,138,221 (+)NCBIHuRef
CHM1_12037,281,298 - 37,305,288 (+)NCBICHM1_1
T2T-CHM13v2.02040,478,618 - 40,502,676 (+)NCBIT2T-CHM13v2.0
Actr5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392158,466,800 - 158,481,131 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2158,466,808 - 158,481,131 (+)EnsemblGRCm39 Ensembl
GRCm382158,624,881 - 158,639,211 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2158,624,888 - 158,639,211 (+)EnsemblGRCm38mm10GRCm38
MGSCv372158,450,649 - 158,464,947 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362158,316,373 - 158,330,639 (+)NCBIMGSCv36mm8
Celera2164,558,392 - 164,572,698 (+)NCBICelera
Cytogenetic Map2H1NCBI
cM Map278.72NCBI
Actr5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83167,702,299 - 167,715,736 (+)NCBIGRCr8
mRatBN7.23147,282,461 - 147,295,870 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3147,282,624 - 147,296,110 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3151,114,460 - 151,127,710 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03159,613,777 - 159,627,027 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03157,349,405 - 157,362,640 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03155,118,567 - 155,132,073 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3155,119,042 - 155,131,829 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03160,477,100 - 160,490,755 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43149,357,984 - 149,371,469 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13149,255,715 - 149,276,796 (+)NCBI
Celera3145,980,319 - 145,993,804 (+)NCBICelera
Cytogenetic Map3q42NCBI
Actr5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544517,991,969 - 18,024,818 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544517,991,969 - 18,024,525 (-)NCBIChiLan1.0ChiLan1.0
ACTR5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22144,473,747 - 44,497,707 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12044,466,844 - 44,490,804 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02035,073,297 - 35,097,955 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12036,181,343 - 36,204,996 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2036,181,343 - 36,204,996 (+)Ensemblpanpan1.1panPan2
ACTR5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12427,154,283 - 27,190,947 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2427,153,314 - 27,179,191 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2426,799,885 - 26,836,498 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02427,850,631 - 27,887,304 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2427,849,688 - 27,875,547 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12427,124,352 - 27,160,983 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02427,232,706 - 27,269,345 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02427,720,799 - 27,757,436 (+)NCBIUU_Cfam_GSD_1.0
Actr5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640176,048,017 - 176,071,825 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365612,676,498 - 2,701,507 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365612,676,515 - 2,701,447 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ACTR5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1741,702,540 - 41,724,393 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11741,702,273 - 41,724,398 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21747,193,583 - 47,215,920 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ACTR5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1224,983,536 - 25,008,225 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl224,980,945 - 25,007,881 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605073,813,425 - 73,838,411 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Actr5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624842912,336 - 933,573 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624842910,178 - 933,495 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in ACTR5
27 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 20q11.22-12(chr20:34541747-39663219)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052766]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052766]|See cases [RCV000052766] Chr20:34541747..39663219 [GRCh38]
Chr20:33129551..38291861 [GRCh37]
Chr20:32593212..37725275 [NCBI36]
Chr20:20q11.22-12		 pathogenic
GRCh38/hg38 20q11.22-13.11(chr20:34249453-43359749)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053002]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053002]|See cases [RCV000053002] Chr20:34249453..43359749 [GRCh38]
Chr20:32837259..41988389 [GRCh37]
Chr20:32300920..41421803 [NCBI36]
Chr20:20q11.22-13.11		 pathogenic
GRCh38/hg38 20p12.2-q12(chr20:9811433-39316956)x3 copy number gain See cases [RCV000052999] Chr20:9811433..39316956 [GRCh38]
Chr20:9792081..37945599 [GRCh37]
Chr20:9740081..37379013 [NCBI36]
Chr20:20p12.2-q12		 pathogenic
GRCh38/hg38 20p13-q13.33(chr20:99557-64277321)x3 copy number gain See cases [RCV000135859] Chr20:99557..64277321 [GRCh38]
Chr20:80198..62908674 [GRCh37]
Chr20:28198..62379118 [NCBI36]
Chr20:20p13-q13.33		 pathogenic
GRCh38/hg38 20q11.22-13.12(chr20:35237946-47631818)x1 copy number loss See cases [RCV000140816] Chr20:35237946..47631818 [GRCh38]
Chr20:33825749..46260562 [GRCh37]
Chr20:33289165..45693969 [NCBI36]
Chr20:20q11.22-13.12		 pathogenic
GRCh37/hg19 20p13-q13.33(chr20:61569-62915555)x3 copy number gain See cases [RCV000510832] Chr20:61569..62915555 [GRCh37]
Chr20:20p13-q13.33		 pathogenic
NM_024855.4(ACTR5):c.725T>G (p.Met242Arg) single nucleotide variant Inborn genetic diseases [RCV003253633] Chr20:38752250 [GRCh38]
Chr20:37380893 [GRCh37]
Chr20:20q11.23		 uncertain significance
GRCh37/hg19 20p13-q13.33(chr20:61569-62915555) copy number gain See cases [RCV000512450] Chr20:61569..62915555 [GRCh37]
Chr20:20p13-q13.33		 pathogenic
GRCh37/hg19 20q11.23-12(chr20:37327665-37675011)x3 copy number gain not provided [RCV000684114] Chr20:37327665..37675011 [GRCh37]
Chr20:20q11.23-12		 uncertain significance
Single allele deletion Focal-onset seizure [RCV001004039] Chr20:34980430..46806549 [GRCh37]
Chr20:20q11.23-13.13		 likely pathogenic
GRCh37/hg19 20p13-q13.33(chr20:63244-62961294)x3 copy number gain not provided [RCV000741059] Chr20:63244..62961294 [GRCh37]
Chr20:20p13-q13.33		 pathogenic
GRCh37/hg19 20p13-q13.33(chr20:63244-62912463)x3 copy number gain not provided [RCV000741057] Chr20:63244..62912463 [GRCh37]
Chr20:20p13-q13.33		 pathogenic
GRCh37/hg19 20p13-q13.33(chr20:63244-62948788)x3 copy number gain not provided [RCV000741058] Chr20:63244..62948788 [GRCh37]
Chr20:20p13-q13.33		 pathogenic
NM_024855.4(ACTR5):c.757G>A (p.Ala253Thr) single nucleotide variant Inborn genetic diseases [RCV003269803] Chr20:38752282 [GRCh38]
Chr20:37380925 [GRCh37]
Chr20:20q11.23		 uncertain significance
NM_024855.4(ACTR5):c.1784G>A (p.Gly595Asp) single nucleotide variant Inborn genetic diseases [RCV002840560] Chr20:38771776 [GRCh38]
Chr20:37400419 [GRCh37]
Chr20:20q11.23		 uncertain significance
NM_024855.4(ACTR5):c.935G>A (p.Arg312Gln) single nucleotide variant Inborn genetic diseases [RCV002779639] Chr20:38755116 [GRCh38]
Chr20:37383759 [GRCh37]
Chr20:20q11.23		 uncertain significance
NM_024855.4(ACTR5):c.68C>T (p.Pro23Leu) single nucleotide variant Inborn genetic diseases [RCV002974029] Chr20:38748546 [GRCh38]
Chr20:37377189 [GRCh37]
Chr20:20q11.23		 uncertain significance
NM_024855.4(ACTR5):c.166G>A (p.Glu56Lys) single nucleotide variant Inborn genetic diseases [RCV002797975] Chr20:38748644 [GRCh38]
Chr20:37377287 [GRCh37]
Chr20:20q11.23		 uncertain significance
NM_024855.4(ACTR5):c.901C>G (p.Gln301Glu) single nucleotide variant Inborn genetic diseases [RCV002869195] Chr20:38755082 [GRCh38]
Chr20:37383725 [GRCh37]
Chr20:20q11.23		 uncertain significance
NM_024855.4(ACTR5):c.1594G>A (p.Asp532Asn) single nucleotide variant Inborn genetic diseases [RCV002924006] Chr20:38771586 [GRCh38]
Chr20:37400229 [GRCh37]
Chr20:20q11.23		 uncertain significance
NM_024855.4(ACTR5):c.1642A>G (p.Asn548Asp) single nucleotide variant Inborn genetic diseases [RCV002875482] Chr20:38771634 [GRCh38]
Chr20:37400277 [GRCh37]
Chr20:20q11.23		 likely benign
NM_024855.4(ACTR5):c.467A>G (p.Tyr156Cys) single nucleotide variant Inborn genetic diseases [RCV002986218] Chr20:38750101 [GRCh38]
Chr20:37378744 [GRCh37]
Chr20:20q11.23		 uncertain significance
NM_024855.4(ACTR5):c.242G>A (p.Gly81Glu) single nucleotide variant Inborn genetic diseases [RCV002742506] Chr20:38748720 [GRCh38]
Chr20:37377363 [GRCh37]
Chr20:20q11.23		 uncertain significance
NM_024855.4(ACTR5):c.509G>C (p.Ser170Thr) single nucleotide variant Inborn genetic diseases [RCV002699636] Chr20:38750143 [GRCh38]
Chr20:37378786 [GRCh37]
Chr20:20q11.23		 uncertain significance
NM_024855.4(ACTR5):c.76C>T (p.His26Tyr) single nucleotide variant Inborn genetic diseases [RCV003006592] Chr20:38748554 [GRCh38]
Chr20:37377197 [GRCh37]
Chr20:20q11.23		 uncertain significance
NM_024855.4(ACTR5):c.38C>T (p.Ala13Val) single nucleotide variant Inborn genetic diseases [RCV002832289] Chr20:38748516 [GRCh38]
Chr20:37377159 [GRCh37]
Chr20:20q11.23		 uncertain significance
NM_024855.4(ACTR5):c.1487G>A (p.Gly496Asp) single nucleotide variant Inborn genetic diseases [RCV002878758] Chr20:38767517 [GRCh38]
Chr20:37396160 [GRCh37]
Chr20:20q11.23		 uncertain significance
NM_024855.4(ACTR5):c.709A>G (p.Ile237Val) single nucleotide variant Inborn genetic diseases [RCV002769535] Chr20:38752234 [GRCh38]
Chr20:37380877 [GRCh37]
Chr20:20q11.23		 uncertain significance
NM_024855.4(ACTR5):c.910C>T (p.Arg304Trp) single nucleotide variant Inborn genetic diseases [RCV002678103] Chr20:38755091 [GRCh38]
Chr20:37383734 [GRCh37]
Chr20:20q11.23		 uncertain significance
NM_024855.4(ACTR5):c.791G>A (p.Arg264Gln) single nucleotide variant Inborn genetic diseases [RCV002656246] Chr20:38754972 [GRCh38]
Chr20:37383615 [GRCh37]
Chr20:20q11.23		 uncertain significance
NM_024855.4(ACTR5):c.146C>G (p.Pro49Arg) single nucleotide variant Inborn genetic diseases [RCV002724399] Chr20:38748624 [GRCh38]
Chr20:37377267 [GRCh37]
Chr20:20q11.23		 uncertain significance
NM_024855.4(ACTR5):c.257G>A (p.Ser86Asn) single nucleotide variant Inborn genetic diseases [RCV003211768] Chr20:38748735 [GRCh38]
Chr20:37377378 [GRCh37]
Chr20:20q11.23		 uncertain significance
NM_024855.4(ACTR5):c.1245G>C (p.Leu415Phe) single nucleotide variant Inborn genetic diseases [RCV003185323] Chr20:38765470 [GRCh38]
Chr20:37394113 [GRCh37]
Chr20:20q11.23		 uncertain significance
NM_024855.4(ACTR5):c.822C>G (p.His274Gln) single nucleotide variant Inborn genetic diseases [RCV003208898] Chr20:38755003 [GRCh38]
Chr20:37383646 [GRCh37]
Chr20:20q11.23		 uncertain significance
NM_024855.4(ACTR5):c.1276C>T (p.Pro426Ser) single nucleotide variant Inborn genetic diseases [RCV003379148] Chr20:38765501 [GRCh38]
Chr20:37394144 [GRCh37]
Chr20:20q11.23		 uncertain significance
NM_024855.4(ACTR5):c.269T>A (p.Leu90Gln) single nucleotide variant Inborn genetic diseases [RCV003381370] Chr20:38748747 [GRCh38]
Chr20:37377390 [GRCh37]
Chr20:20q11.23		 uncertain significance
NM_024855.4(ACTR5):c.883C>G (p.Gln295Glu) single nucleotide variant Inborn genetic diseases [RCV003350325] Chr20:38755064 [GRCh38]
Chr20:37383707 [GRCh37]
Chr20:20q11.23		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:205
Count of miRNA genes:189
Interacting mature miRNAs:192
Transcripts:ENST00000243903
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
SHGC-104591  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372037,386,220 - 37,386,551UniSTSGRCh37
Build 362036,819,634 - 36,819,965RGDNCBI36
Celera2034,096,935 - 34,097,266RGD
Cytogenetic Map20q11.23UniSTS
HuRef2034,123,361 - 34,123,692UniSTS
TNG Radiation Hybrid Map2017350.0UniSTS
RH65503  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372037,400,543 - 37,400,670UniSTSGRCh37
Build 362036,833,957 - 36,834,084RGDNCBI36
Celera2034,111,247 - 34,111,374RGD
Cytogenetic Map20q11.23UniSTS
HuRef2034,137,675 - 34,137,802UniSTS
GeneMap99-GB4 RH Map20232.43UniSTS
NCBI RH Map20338.6UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage entire extraembryonic component
High
Medium 1111 1253 945 140 1132 88 3355 519 1450 213 1361 1307 66 804 1925 3
Low 1321 1723 778 482 808 376 1000 1674 2258 205 87 301 105 400 863 1
Below cutoff 8 8

Sequence


Reference Sequences
RefSeq Acc Id: ENST00000243903   ⟹   ENSP00000243903
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2038,748,460 - 38,772,520 (+)Ensembl
RefSeq Acc Id: NM_024855   ⟹   NP_079131
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382038,748,460 - 38,772,520 (+)NCBI
GRCh372037,376,933 - 37,401,089 (+)NCBI
Build 362036,810,511 - 36,834,503 (+)NCBI Archive
Celera2034,087,821 - 34,111,793 (+)RGD
HuRef2034,114,312 - 34,138,221 (+)RGD
CHM1_12037,281,298 - 37,305,288 (+)NCBI
T2T-CHM13v2.02040,478,618 - 40,502,676 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_079131   ⟸   NM_024855
- UniProtKB: Q9BRN0 (UniProtKB/Swiss-Prot),   Q8N724 (UniProtKB/Swiss-Prot),   Q8IUY5 (UniProtKB/Swiss-Prot),   Q86WF7 (UniProtKB/Swiss-Prot),   Q9BVB7 (UniProtKB/Swiss-Prot),   Q9H9F9 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSP00000243903   ⟸   ENST00000243903

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9H9F9-F1-model_v2 AlphaFold Q9H9F9 1-607 view protein structure

Promoters
RGD ID:6798510
Promoter ID:HG_KWN:39411
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:OTTHUMT00000079205
Position:
Human AssemblyChrPosition (strand)Source
Build 362036,810,156 - 36,810,656 (+)MPROMDB
RGD ID:13206927
Promoter ID:EPDNEW_H27044
Type:initiation region
Name:ACTR5_1
Description:ARP5 actin-related protein 5 homolog
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh382038,748,467 - 38,748,527EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:14671 AgrOrtholog
COSMIC ACTR5 COSMIC
Ensembl Genes ENSG00000101442 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000243903 ENTREZGENE
  ENST00000243903.6 UniProtKB/Swiss-Prot
Gene3D-CATH 3.30.420.40 UniProtKB/Swiss-Prot
GTEx ENSG00000101442 GTEx
HGNC ID HGNC:14671 ENTREZGENE
Human Proteome Map ACTR5 Human Proteome Map
InterPro Actin UniProtKB/Swiss-Prot
  Actin_CS UniProtKB/Swiss-Prot
  ATPase_NBD UniProtKB/Swiss-Prot
KEGG Report hsa:79913 UniProtKB/Swiss-Prot
NCBI Gene 79913 ENTREZGENE
OMIM 619730 OMIM
PANTHER PTHR11937 UniProtKB/Swiss-Prot
  PTHR11937:SF16 UniProtKB/Swiss-Prot
Pfam Actin UniProtKB/Swiss-Prot
PharmGKB PA24490 PharmGKB
PROSITE ACTINS_2 UniProtKB/Swiss-Prot
SMART ACTIN UniProtKB/Swiss-Prot
Superfamily-SCOP SSF53067 UniProtKB/Swiss-Prot
UniProt ARP5_HUMAN UniProtKB/Swiss-Prot
  Q86WF7 ENTREZGENE
  Q8IUY5 ENTREZGENE
  Q8N724 ENTREZGENE
  Q9BRN0 ENTREZGENE
  Q9BVB7 ENTREZGENE
  Q9H9F9 ENTREZGENE
UniProt Secondary Q86WF7 UniProtKB/Swiss-Prot
  Q8IUY5 UniProtKB/Swiss-Prot
  Q8N724 UniProtKB/Swiss-Prot
  Q9BRN0 UniProtKB/Swiss-Prot
  Q9BVB7 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-01-15 ACTR5  actin related protein 5    ARP5 actin related protein 5 homolog  Symbol and/or name change 5135510 APPROVED
2017-05-02 ACTR5  ARP5 actin related protein 5 homolog    ARP5 actin-related protein 5 homolog  Symbol and/or name change 5135510 APPROVED
2016-04-12 ACTR5  ARP5 actin-related protein 5 homolog    ARP5 actin-related protein 5 homolog (yeast)  Symbol and/or name change 5135510 APPROVED