EPC1 (enhancer of polycomb homolog 1) - Rat Genome Database

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Gene: EPC1 (enhancer of polycomb homolog 1) Pan paniscus
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Symbol: EPC1
Name: enhancer of polycomb homolog 1
RGD ID: 11984990
Description: ENCODES a protein that exhibits chromatin-protein adaptor activity (inferred); enzyme-substrate adaptor activity (inferred); INVOLVED IN negative regulation of gene expression, epigenetic (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH genetic disease (ortholog); Neointima (ortholog); FOUND IN NuA4 histone acetyltransferase complex (ortholog); nucleosome (ortholog); piccolo histone acetyltransferase complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2844,918,832 - 45,029,617 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11044,924,971 - 45,034,770 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01032,398,557 - 32,509,146 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11032,985,456 - 33,095,070 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1032,985,456 - 33,095,070 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
EPC1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2844,918,832 - 45,029,617 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11044,924,971 - 45,034,770 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01032,398,557 - 32,509,146 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11032,985,456 - 33,095,070 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1032,985,456 - 33,095,070 (-)Ensemblpanpan1.1panPan2
EPC1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381032,267,751 - 32,378,769 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1032,267,751 - 32,378,798 (-)EnsemblGRCh38hg38GRCh38
GRCh371032,556,679 - 32,667,697 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361032,597,865 - 32,676,119 (-)NCBINCBI36Build 36hg18NCBI36
Build 341032,597,864 - 32,676,119NCBI
Celera1032,323,085 - 32,401,333 (-)NCBICelera
Cytogenetic Map10p11.22NCBI
HuRef1032,276,952 - 32,387,816 (-)NCBIHuRef
CHM1_11032,558,317 - 32,669,300 (-)NCBICHM1_1
T2T-CHM13v2.01032,296,867 - 32,407,873 (-)NCBIT2T-CHM13v2.0
Epc1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39186,435,951 - 6,516,108 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl186,435,951 - 6,516,108 (-)EnsemblGRCm39 Ensembl
GRCm38186,435,951 - 6,516,108 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl186,435,951 - 6,516,108 (-)EnsemblGRCm38mm10GRCm38
MGSCv37186,435,949 - 6,516,085 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36186,435,949 - 6,516,085 (-)NCBIMGSCv36mm8
Celera186,483,184 - 6,569,258 (-)NCBICelera
Cytogenetic Map18A1NCBI
cM Map184.48NCBI
Epc1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81759,198,513 - 59,289,535 (-)NCBIGRCr8
mRatBN7.21754,503,358 - 54,594,444 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1754,503,358 - 54,594,425 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1757,670,117 - 57,762,113 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01761,673,219 - 61,765,221 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01755,840,859 - 55,932,853 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01757,303,968 - 57,394,975 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1757,304,933 - 57,394,985 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01755,332,012 - 55,423,030 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41763,040,151 - 63,131,954 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11763,050,987 - 63,115,013 (-)NCBI
Celera1750,484,141 - 50,575,159 (-)NCBICelera
Cytogenetic Map17q12.1NCBI
Epc1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542923,817,254 - 23,909,946 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542923,819,261 - 23,910,279 (-)NCBIChiLan1.0ChiLan1.0
EPC1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1214,566,177 - 14,659,774 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl214,565,560 - 14,659,353 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha212,054,448 - 12,148,508 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0212,801,929 - 12,896,656 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl212,827,078 - 12,895,505 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1212,267,471 - 12,337,031 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0212,133,446 - 12,227,913 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0212,407,208 - 12,501,657 (+)NCBIUU_Cfam_GSD_1.0
Epc1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934411,467,190 - 11,551,016 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936574964,619 - 1,050,571 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936574966,655 - 1,050,537 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EPC1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1042,836,047 - 42,946,857 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11042,835,280 - 42,946,859 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21047,431,316 - 47,572,044 (-)NCBISscrofa10.2Sscrofa10.2susScr3
EPC1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1931,586,402 - 31,698,876 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl931,585,246 - 31,665,592 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605640,587,401 - 40,700,708 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Epc1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248054,651,051 - 4,756,899 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248054,653,730 - 4,684,211 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSPPAT00000041641   ⟹   ENSPPAP00000018896
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1032,985,456 - 33,095,070 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000041651   ⟹   ENSPPAP00000018905
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1032,985,456 - 33,063,537 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000041654   ⟹   ENSPPAP00000018908
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1032,985,456 - 33,063,523 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000041656   ⟹   ENSPPAP00000018910
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1033,061,835 - 33,063,220 (-)Ensembl
RefSeq Acc Id: XM_003814795   ⟹   XP_003814843
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2844,918,832 - 44,997,781 (-)NCBI
NHGRI_mPanPan11044,924,971 - 45,002,712 (-)NCBI
Mhudiblu_PPA_v01032,398,557 - 32,477,131 (-)NCBI
PanPan1.11032,985,456 - 33,063,523 (-)NCBI
Sequence:
RefSeq Acc Id: XM_003814796   ⟹   XP_003814844
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2844,918,832 - 44,997,786 (-)NCBI
NHGRI_mPanPan11044,924,971 - 45,002,755 (-)NCBI
Mhudiblu_PPA_v01032,398,557 - 32,477,093 (-)NCBI
PanPan1.11032,985,456 - 33,063,535 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008967636   ⟹   XP_008965884
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2844,918,832 - 45,029,617 (-)NCBI
NHGRI_mPanPan11044,924,971 - 45,034,770 (-)NCBI
Mhudiblu_PPA_v01032,398,557 - 32,509,146 (-)NCBI
PanPan1.11032,985,456 - 33,095,070 (-)NCBI
Sequence:
RefSeq Acc Id: XM_057298843   ⟹   XP_057154826
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2844,918,832 - 45,029,427 (-)NCBI
NHGRI_mPanPan11044,924,971 - 45,034,766 (-)NCBI
RefSeq Acc Id: XP_008965884   ⟸   XM_008967636
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_003814844   ⟸   XM_003814796
- Peptide Label: isoform X1
- UniProtKB: A0A2R9ASZ9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003814843   ⟸   XM_003814795
- Peptide Label: isoform X2
- UniProtKB: A0A2R9AP37 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSPPAP00000018905   ⟸   ENSPPAT00000041651
RefSeq Acc Id: ENSPPAP00000018908   ⟸   ENSPPAT00000041654
RefSeq Acc Id: ENSPPAP00000018910   ⟸   ENSPPAT00000041656
RefSeq Acc Id: ENSPPAP00000018896   ⟸   ENSPPAT00000041641
RefSeq Acc Id: XP_057154826   ⟸   XM_057298843
- Peptide Label: isoform X4
- UniProtKB: A0A2R9ANG8 (UniProtKB/TrEMBL)

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000032605 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000041641.1 UniProtKB/TrEMBL
  ENSPPAT00000041651.1 UniProtKB/TrEMBL
  ENSPPAT00000041654.1 UniProtKB/TrEMBL
  ENSPPAT00000041656.1 UniProtKB/TrEMBL
InterPro Enhancer_polycomb UniProtKB/TrEMBL
  Enhancer_polycomb-like_N UniProtKB/TrEMBL
  Enhancer_polycomb_C UniProtKB/TrEMBL
KEGG Report pps:100994489 UniProtKB/TrEMBL
NCBI Gene EPC1 ENTREZGENE
PANTHER ENHANCER OF POLYCOMB HOMOLOG 1 UniProtKB/TrEMBL
  PTHR14898 UniProtKB/TrEMBL
Pfam E_Pc_C UniProtKB/TrEMBL
  EPL1 UniProtKB/TrEMBL
UniProt A0A2R9ANG8 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9AP37 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9ASZ9 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9AT06_PANPA UniProtKB/TrEMBL