Nfrkb (nuclear factor related to kappaB binding protein) - Rat Genome Database

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Gene: Nfrkb (nuclear factor related to kappaB binding protein) Chinchilla lanigera
Analyze
Symbol: Nfrkb
Name: nuclear factor related to kappaB binding protein
RGD ID: 8705257
Description: ENCODES a protein that exhibits protease binding (ortholog); INVOLVED IN chromatin remodeling (ortholog); positive regulation of DNA repair (ortholog); positive regulation of DNA-templated transcription (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH Chromosome 11, Partial Trisomy 11q (ortholog); Dwarfism (ortholog); genetic disease (ortholog); FOUND IN Ino80 complex (ortholog); nucleoplasm (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541230,813,769 - 30,849,001 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541230,817,151 - 30,848,992 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
Ino80 complex  (ISO)
nucleoplasm  (ISO)
nucleus  (ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Nfrkb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541230,813,769 - 30,849,001 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541230,817,151 - 30,848,992 (-)NCBIChiLan1.0ChiLan1.0
NFRKB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811129,863,636 - 129,895,578 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11129,863,636 - 129,895,590 (-)EnsemblGRCh38hg38GRCh38
GRCh3711129,733,531 - 129,765,473 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611129,239,568 - 129,268,114 (-)NCBINCBI36Build 36hg18NCBI36
Build 3411129,239,574 - 129,268,114NCBI
Celera11126,901,823 - 126,933,652 (-)NCBICelera
Cytogenetic Map11q24.3NCBI
HuRef11125,685,954 - 125,717,786 (-)NCBIHuRef
CHM1_111129,619,262 - 129,651,095 (-)NCBICHM1_1
T2T-CHM13v2.011129,899,341 - 129,931,605 (-)NCBIT2T-CHM13v2.0
Nfrkb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39931,297,476 - 31,332,629 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl931,297,488 - 31,332,629 (+)EnsemblGRCm39 Ensembl
GRCm38931,386,162 - 31,421,333 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl931,386,192 - 31,421,333 (+)EnsemblGRCm38mm10GRCm38
MGSCv37931,193,777 - 31,228,918 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36931,135,778 - 31,170,898 (+)NCBIMGSCv36mm8
Celera928,647,176 - 28,682,323 (+)NCBICelera
Cytogenetic Map9A4NCBI
cM Map916.86NCBI
Nfrkb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8838,089,574 - 38,121,506 (+)NCBIGRCr8
mRatBN7.2829,831,802 - 29,863,360 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl829,831,812 - 29,863,359 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx833,900,511 - 33,932,132 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0832,194,903 - 32,226,523 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0830,062,922 - 30,094,466 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0832,530,412 - 32,561,955 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl832,530,412 - 32,561,955 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0832,555,212 - 32,586,756 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4831,144,717 - 31,176,261 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1831,156,280 - 31,184,016 (+)NCBI
Celera831,292,880 - 31,324,404 (+)NCBICelera
Cytogenetic Map8q13NCBI
NFRKB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v29130,545,293 - 130,577,180 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan111131,655,426 - 131,687,302 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011124,676,456 - 124,708,349 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111128,572,240 - 128,603,805 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11128,572,240 - 128,601,779 (-)Ensemblpanpan1.1panPan2
NFRKB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.154,944,278 - 4,982,377 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl54,946,893 - 4,980,996 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha55,003,803 - 5,042,799 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.054,901,507 - 4,940,392 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl54,901,545 - 4,940,396 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.154,966,970 - 5,002,430 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.054,945,914 - 4,984,789 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.054,973,932 - 5,012,705 (+)NCBIUU_Cfam_GSD_1.0
Nfrkb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947111,979,867 - 112,014,548 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365722,435,847 - 2,471,655 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365722,435,875 - 2,468,848 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NFRKB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl956,614,227 - 56,656,056 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1956,616,865 - 56,656,068 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2962,782,480 - 62,795,887 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NFRKB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11120,935,175 - 120,968,053 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1120,936,104 - 120,968,005 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660435,126,292 - 5,158,917 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nfrkb
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248124,249,350 - 4,280,182 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248124,248,077 - 4,282,948 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000022586   ⟹   ENSCLAP00000022381
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495541230,813,769 - 30,849,001 (-)Ensembl
RefSeq Acc Id: XM_005378552   ⟹   XP_005378609
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541230,817,151 - 30,848,992 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005378553   ⟹   XP_005378610
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541230,817,151 - 30,848,992 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013511175   ⟹   XP_013366629
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541230,817,151 - 30,848,992 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013511176   ⟹   XP_013366630
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541230,817,151 - 30,848,992 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013511177   ⟹   XP_013366631
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541230,817,151 - 30,848,992 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_005378610   ⟸   XM_005378553
- Peptide Label: isoform X3
- UniProtKB: A0A8C2W352 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005378609   ⟸   XM_005378552
- Peptide Label: isoform X1
- UniProtKB: A0A8C2W352 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013366629   ⟸   XM_013511175
- Peptide Label: isoform X1
- UniProtKB: A0A8C2W352 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013366630   ⟸   XM_013511176
- Peptide Label: isoform X2
- UniProtKB: A0A8C2W352 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013366631   ⟸   XM_013511177
- Peptide Label: isoform X4
- UniProtKB: A0A8C2W352 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000022381   ⟸   ENSCLAT00000022586
Protein Domains
DEUBAD


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000015352 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000022586 ENTREZGENE
  ENSCLAT00000022586.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.2430 UniProtKB/TrEMBL
InterPro DEUBAD_dom UniProtKB/TrEMBL
  NFRKB UniProtKB/TrEMBL
  NFRKB_winged_dom UniProtKB/TrEMBL
  NFRKB_winged_sf UniProtKB/TrEMBL
NCBI Gene Nfrkb ENTREZGENE
PANTHER NUCLEAR FACTOR RELATED TO KAPPA-B-BINDING PROTEIN UniProtKB/TrEMBL
  PTHR13052 UniProtKB/TrEMBL
Pfam NFRKB_winged UniProtKB/TrEMBL
PROSITE DEUBAD UniProtKB/TrEMBL
UniProt A0A8C2W352 ENTREZGENE, UniProtKB/TrEMBL