Morf4l2 (mortality factor 4 like 2) - Rat Genome Database
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Gene: Morf4l2 (mortality factor 4 like 2) Rattus norvegicus
Analyze
Symbol: Morf4l2
Name: mortality factor 4 like 2
RGD ID: 1359471
Description: Involved in positive regulation of striated muscle cell differentiation and positive regulation of transcription by RNA polymerase II. Predicted to localize to nucleolus; nucleoplasm; and plasma membrane. Orthologous to human MORF4L2 (mortality factor 4 like 2); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; INTERACTS WITH (+)-schisandrin B; 2,4-dinitrotoluene; 3-chloropropane-1,2-diol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: liver regeneration-related protein LRRG00119; LRRG00119; MGC93688; MGC94357; MORF-related gene X; mortality factor 4-like protein 2; transcription factor-like protein MRGX
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2X100,082,562 - 100,093,658 (-)NCBI
Rnor_6.0 EnsemblX107,394,486 - 107,405,564 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0X107,394,468 - 107,405,564 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X107,278,227 - 107,289,323 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X124,382,809 - 124,393,906 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1X124,456,246 - 124,467,339 (-)NCBI
CeleraX100,917,630 - 100,928,726 (-)NCBICelera
Cytogenetic MapXq32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:10942595   PMID:15489334  


Genomics

Comparative Map Data
Morf4l2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2X100,082,562 - 100,093,658 (-)NCBI
Rnor_6.0 EnsemblX107,394,486 - 107,405,564 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0X107,394,468 - 107,405,564 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X107,278,227 - 107,289,323 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X124,382,809 - 124,393,906 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1X124,456,246 - 124,467,339 (-)NCBI
CeleraX100,917,630 - 100,928,726 (-)NCBICelera
Cytogenetic MapXq32NCBI
MORF4L2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 EnsemblX103,675,496 - 103,688,158 (-)EnsemblGRCh38hg38GRCh38
GRCh38X103,675,498 - 103,688,047 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X102,930,426 - 102,942,975 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X102,817,089 - 102,828,252 (-)NCBINCBI36hg18NCBI36
Build 34X102,736,577 - 102,747,741NCBI
CeleraX103,369,434 - 103,382,094 (-)NCBI
Cytogenetic MapXq22.2NCBI
HuRefX92,587,851 - 92,600,511 (-)NCBIHuRef
CHM1_1X102,823,433 - 102,836,101 (-)NCBICHM1_1
Morf4l2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X135,633,691 - 135,644,435 (-)NCBIGRCm39mm39
GRCm39 EnsemblX135,633,691 - 135,644,439 (-)Ensembl
GRCm38X136,732,942 - 136,743,686 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX136,732,942 - 136,743,690 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X133,267,481 - 133,278,225 (-)NCBIGRCm37mm9NCBIm37
MGSCv36X132,079,306 - 132,087,973 (-)NCBImm8
CeleraX120,016,542 - 120,027,206 (-)NCBICelera
Cytogenetic MapXF1NCBI
Morf4l2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_004955548682,409 - 685,886 (-)NCBIChiLan1.0ChiLan1.0
MORF4L2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1X103,285,742 - 103,298,493 (-)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v0X92,904,721 - 92,917,340 (-)NCBIMhudiblu_PPA_v0panPan3
MORF4L2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 EnsemblX77,085,599 - 77,086,465 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1X77,084,940 - 77,097,900 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Morf4l2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_00493649910,636,711 - 10,647,442 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MORF4L2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX84,552,705 - 84,569,030 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X84,553,770 - 84,566,304 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X98,342,575 - 98,355,075 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MORF4L2
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X91,566,051 - 91,579,084 (-)NCBI
ChlSab1.1 EnsemblX91,566,712 - 91,567,575 (-)Ensembl
Morf4l2
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624954246,881 - 258,360 (+)NCBI

Position Markers
RH126514  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0X107,394,527 - 107,394,780NCBIRnor6.0
Rnor_6.09121,442,558 - 121,442,713NCBIRnor6.0
Rnor_5.09120,888,717 - 120,888,872UniSTSRnor5.0
Rnor_5.0X107,278,286 - 107,278,539UniSTSRnor5.0
RGSC_v3.49112,237,326 - 112,237,481UniSTSRGSC3.4
RGSC_v3.4X124,382,868 - 124,383,121UniSTSRGSC3.4
Celera9109,943,791 - 109,943,946UniSTS
CeleraX100,917,689 - 100,917,942UniSTS
Cytogenetic Map9q38UniSTS
Cytogenetic MapXq35UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61430Cia18Collagen induced arthritis QTL 183.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X15688119127888215Rat
61431Cia19Collagen induced arthritis QTL 194.4joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X70352120127888215Rat
724551Glom1Glomerulus QTL 12.80.0004kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)X82930791127930791Rat
738035Stresp1Stress response QTL 14.960.000011stress-related behavior trait (VT:0010451)defensive burying - copingX44557974120045269Rat
1598837Memor13Memory QTL 133.2exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X44320616158345622Rat
1598872Memor14Memory QTL 144.5exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X101333032146333032Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:525
Count of miRNA genes:262
Interacting mature miRNAs:313
Transcripts:ENSRNOT00000003247
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 41 11 8
Low
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000003247   ⟹   ENSRNOP00000003247
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 EnsemblX107,394,486 - 107,405,564 (-)Ensembl
RefSeq Acc Id: NM_001007714   ⟹   NP_001007715
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X100,082,562 - 100,093,658 (-)NCBI
Rnor_6.0X107,394,468 - 107,405,564 (-)NCBI
Rnor_5.0X107,278,227 - 107,289,323 (-)NCBI
RGSC_v3.4X124,382,809 - 124,393,906 (-)RGD
CeleraX100,917,630 - 100,928,726 (-)RGD
Sequence:
RefSeq Acc Id: XM_006257295   ⟹   XP_006257357
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X100,082,562 - 100,091,226 (-)NCBI
Rnor_6.0X107,394,468 - 107,403,085 (-)NCBI
Rnor_5.0X107,278,227 - 107,289,323 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006257296   ⟹   XP_006257358
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X100,082,562 - 100,092,847 (-)NCBI
Rnor_6.0X107,394,468 - 107,404,757 (-)NCBI
Rnor_5.0X107,278,227 - 107,289,323 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006257297   ⟹   XP_006257359
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X100,082,562 - 100,091,226 (-)NCBI
Rnor_6.0X107,394,468 - 107,403,085 (-)NCBI
Rnor_5.0X107,278,227 - 107,289,323 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017602069   ⟹   XP_017457558
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0X107,394,468 - 107,403,182 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039099802   ⟹   XP_038955730
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X100,082,562 - 100,092,847 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_001007715   ⟸   NM_001007714
- UniProtKB: Q6QI89 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006257358   ⟸   XM_006257296
- Peptide Label: isoform X1
- UniProtKB: Q6QI89 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006257359   ⟸   XM_006257297
- Peptide Label: isoform X1
- UniProtKB: Q6QI89 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006257357   ⟸   XM_006257295
- Peptide Label: isoform X1
- UniProtKB: Q6QI89 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_017457558   ⟸   XM_017602069
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSRNOP00000003247   ⟸   ENSRNOT00000003247
RefSeq Acc Id: XP_038955730   ⟸   XM_039099802
- Peptide Label: isoform X1
Protein Domains
MRG

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Damaging Variants


Assembly: Rnor_5.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
X 107279236 107279237 G T snv DOB/Oda (KyushuU)
X 107279437 107279438 C A snv LE/Stm (KyushuU), FHH/EurMcwi (MCW), FHL/EurMcwi (MCW)


Assembly: Rnor_6.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
X 107395648 107395649 A G snv Buf/N (MCW), ACI/N (MCW)
X 107395678 107395679 C A snv LE/Stm (RGD), FHL/EurMcwi (MCW), FHH/EurMcwi (MCW)
X 107395994 107395995 G T snv WKY/N (MCW), WN/N (MCW), MR/N (MCW), M520/N (MCW), F344/NRrrc (MCW), BN/SsN (MCW), ACI/N (MCW), Buf/N (MCW)


Assembly: RGSC_v3.4

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
X 124383989 124383990 A G snv SS/JrHsdMcwi (MDC), BUF/N (KNAW), BN/NHsdMcwi (KNAW), ACI/N (KNAW)
X 124384019 124384020 C A snv FHH/EurMcwi (MCW), LE/Stm (KNAW), FHL/EurMcwi (MCW)
X 124384335 124384336 G T snv FHL/EurMcwi (MCW), F344/NRrrc (KNAW), M520/N (KNAW), MR/N (KNAW), WKY/N (KNAW), WN/N (KNAW), ACI/N (KNAW), SS/JrHsdMcwi (MDC), SS/JrHsdMcwi (MCW), BUF/N (KNAW), BN/NHsdMcwi (KNAW), SHRSP/Gcrc (MDC), BN/SsN (KNAW)


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1359471 AgrOrtholog
Ensembl Genes ENSRNOG00000002389 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSRNOP00000003247 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000003247 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.274.30 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7133330 IMAGE-MGC_LOAD
InterPro MRG UniProtKB/Swiss-Prot
  MRG_C_sf UniProtKB/Swiss-Prot
  MRG_dom UniProtKB/Swiss-Prot
  MRGX UniProtKB/Swiss-Prot
KEGG Report rno:317413 UniProtKB/Swiss-Prot
MGC_CLONE MGC:94357 IMAGE-MGC_LOAD
NCBI Gene 317413 ENTREZGENE
PANTHER PTHR10880 UniProtKB/Swiss-Prot
  PTHR10880:SF25 UniProtKB/Swiss-Prot
Pfam MRG UniProtKB/Swiss-Prot
PhenoGen Morf4l2 PhenoGen
PIRSF HAT_Nua4_EAF3/MRG15 UniProtKB/Swiss-Prot
PROSITE MRG UniProtKB/Swiss-Prot
UniProt MO4L2_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2006-03-30 Morf4l2  mortality factor 4 like 2    MORF-related gene X  Name updated 1299863 APPROVED
2005-07-29 Morf4l2  MORF-related gene X      Symbol and Name status set to provisional 70820 PROVISIONAL