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ONTOLOGY REPORT - ANNOTATIONS

Term:cell proliferation in midbrain
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Accession:GO:0033278 term browser browse the term
Definition:The multiplication or reproduction of cells, resulting in the expansion of a cell population in the midbrain.
Synonyms:exact_synonym: cell proliferation in mesencephalon
 related_synonym: mesencepahalic cell proliferation

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cell proliferation in midbrain term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G N Fzd3 frizzled class receptor 3 acts_upstream_of_or_within ISO (PMID:19842188) MGI PMID:19842188 NCBI chrNW_004624758:23,147,512...23,240,711
Ensembl chrNW_004624758:23,147,452...23,230,879 		JBrowse link
G G FZD3 frizzled class receptor 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19842188) Ensembl
MGI		 PMID:19842188 GO_REF:0000107 NCBI chr 8:26,598,544...26,668,983
Ensembl chr 8:26,598,610...26,667,543 		JBrowse link
G P FZD3 frizzled class receptor 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19842188) Ensembl
MGI		 PMID:19842188 GO_REF:0000107 NCBI chr14:12,281,127...12,394,768
Ensembl chr14:12,281,155...12,390,530 		JBrowse link
G S Fzd3 frizzled class receptor 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19842188) Ensembl
MGI		 PMID:19842188 GO_REF:0000107 NCBI chrNW_004936675:1,275,500...1,334,878
Ensembl chrNW_004936675:1,275,470...1,333,540 		JBrowse link
G D FZD3 frizzled class receptor 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19842188) Ensembl
MGI		 PMID:19842188 GO_REF:0000107 NCBI chr25:28,969,126...29,075,763
Ensembl chr25:28,952,477...29,075,851 		JBrowse link
G B FZD3 frizzled class receptor 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19842188) Ensembl
MGI		 PMID:19842188 GO_REF:0000107 NCBI chr 8:27,773,699...27,853,980
Ensembl chr 8:24,973,644...25,042,115 		JBrowse link
G C Fzd3 frizzled class receptor 3 acts_upstream_of_or_within ISO (PMID:19842188) MGI PMID:19842188 NCBI chrNW_004955403:50,899,658...50,959,077
Ensembl chrNW_004955403:50,899,523...50,959,071 		JBrowse link
G R Fzd3 frizzled class receptor 3 acts_upstream_of_or_within ISO MGI:108474 (PMID:19842188) RGD PMID:19842188 NCBI chr15:39,421,366...39,488,369
Ensembl chr15:39,421,355...39,488,369 		JBrowse link
G M Fzd3 frizzled class receptor 3 acts_upstream_of_or_within IGI (PMID:19842188) MGI PMID:19842188 NCBI chr14:65,429,890...65,499,912
Ensembl chr14:65,429,898...65,499,912 		JBrowse link
G H FZD3 frizzled class receptor 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19842188) Ensembl
MGI		 PMID:19842188 GO_REF:0000107 NCBI chr 8:28,494,212...28,574,258
Ensembl chr 8:28,494,205...28,574,267 		JBrowse link
G N Fzd6 frizzled class receptor 6 acts_upstream_of_or_within ISO (PMID:19842188) MGI PMID:19842188 NCBI chrNW_004624763:19,861,837...19,888,626 JBrowse link
G G FZD6 frizzled class receptor 6 acts_upstream_of_or_within ISO (PMID:19842188) MGI PMID:19842188 NCBI chr 8:98,154,173...98,187,864
Ensembl chr 8:98,154,196...98,188,069 		JBrowse link
G P FZD6 frizzled class receptor 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19842188) Ensembl
MGI		 PMID:19842188 GO_REF:0000107 NCBI chr 4:33,811,159...33,844,556
Ensembl chr 4:33,809,809...33,844,656 		JBrowse link
G S Fzd6 frizzled class receptor 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19842188) Ensembl
MGI		 PMID:19842188 GO_REF:0000107 NCBI chrNW_004936470:40,416,254...40,454,717
Ensembl chrNW_004936470:40,416,014...40,454,062 		JBrowse link
G D FZD6 frizzled class receptor 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19842188) Ensembl
MGI		 PMID:19842188 GO_REF:0000107 NCBI chr13:4,732,541...4,771,294
Ensembl chr13:4,733,017...4,772,115 		JBrowse link
G B FZD6 frizzled class receptor 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19842188) Ensembl
MGI		 PMID:19842188 GO_REF:0000107 NCBI chr 8:99,954,523...99,989,153
Ensembl chr 8:102,110,317...102,144,363 		JBrowse link
G C Fzd6 frizzled class receptor 6 acts_upstream_of_or_within ISO (PMID:19842188) MGI PMID:19842188 NCBI chrNW_004955417:27,465,730...27,493,752
Ensembl chrNW_004955417:27,465,701...27,494,790 		JBrowse link
G R Fzd6 frizzled class receptor 6 acts_upstream_of_or_within ISO MGI:108476 (PMID:19842188) RGD PMID:19842188 NCBI chr 7:70,055,012...70,086,781
Ensembl chr 7:70,055,068...70,086,776 		JBrowse link
G M Fzd6 frizzled class receptor 6 acts_upstream_of_or_within IGI (PMID:19842188) MGI PMID:19842188 NCBI chr15:38,869,673...38,901,587
Ensembl chr15:38,869,429...38,901,583 		JBrowse link
G H FZD6 frizzled class receptor 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19842188) Ensembl
MGI		 PMID:19842188 GO_REF:0000107 NCBI chr 8:103,298,494...103,332,866
Ensembl chr 8:103,298,433...103,332,866 		JBrowse link
G N Wnt1 Wnt family member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624816:3,209,605...3,212,969
Ensembl chrNW_004624816:3,209,699...3,212,606 		JBrowse link
G G WNT1 Wnt family member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:45,217,402...45,222,996
Ensembl chr11:45,219,027...45,222,017 		JBrowse link
G P WNT1 Wnt family member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:15,010,607...15,015,007
Ensembl chr 5:15,010,786...15,014,998 		JBrowse link
G S Wnt1 Wnt family member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936512:6,781,001...6,785,358
Ensembl chrNW_004936512:6,780,882...6,785,358 		JBrowse link
G D WNT1 Wnt family member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:5,588,151...5,592,254
Ensembl chr27:5,574,940...5,592,060 		JBrowse link
G B WNT1 Wnt family member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:39,767,839...39,772,460
Ensembl chr12:40,648,413...40,652,583 		JBrowse link
G C Wnt1 Wnt family member 1 involved_in ISO (MGI:2679774|PMID:14557550), (MGI:3045659|PMID:15121182) ParkinsonsUK-UCL PMID:14557550 PMID:15121182 MGI:2679774 MGI:3045659 NCBI chrNW_004955500:7,797,063...7,811,142
Ensembl chrNW_004955500:7,797,060...7,811,167 		JBrowse link
G R Wnt1 Wnt family member 1 involved_in ISO (MGI:2679774|PMID:14557550), (MGI:3045659|PMID:15121182) RGD PMID:14557550 PMID:15121182 MGI:2679774 MGI:3045659 NCBI chr 7:129,938,604...129,942,651
Ensembl chr 7:129,938,604...129,942,651 		JBrowse link
G M Wnt1 wingless-type MMTV integration site family, member 1 involved_in IDA (MGI:2679774|PMID:14557550), (MGI:3045659|PMID:15121182) ParkinsonsUK-UCL PMID:14557550 PMID:15121182 MGI:2679774 MGI:3045659 NCBI chr15:98,687,738...98,691,711
Ensembl chr15:98,687,738...98,691,718 		JBrowse link
G H WNT1 Wnt family member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:48,978,322...48,982,620
Ensembl chr12:48,978,322...48,982,620 		JBrowse link
G N Wnt2 Wnt family member 2 involved_in ISO (MGI:4461115|PMID:20018874)
(PMID:20018874)		 CACAO
ParkinsonsUK-UCL		 PMID:20018874 MGI:4461115 NCBI chrNW_004624827:2,045,733...2,088,284
Ensembl chrNW_004624827:2,045,595...2,089,442 		JBrowse link
G G WNT2 Wnt family member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:85,955,517...86,005,664
Ensembl chr21:85,955,145...86,001,730 		JBrowse link
G P WNT2 Wnt family member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:28,945,825...28,993,969
Ensembl chr18:28,946,326...28,993,961 		JBrowse link
G S Wnt2 Wnt family member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936589:1,825,209...1,866,898
Ensembl chrNW_004936589:1,825,209...1,866,889 		JBrowse link
G D WNT2 Wnt family member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:56,123,735...56,172,113
Ensembl chr14:56,129,248...56,172,069 		JBrowse link
G B WNT2 Wnt family member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:109,244,772...109,291,472
Ensembl chr 7:121,936,031...121,985,862 		JBrowse link
G C Wnt2 Wnt family member 2 involved_in ISO (PMID:20018874)
(MGI:4461115|PMID:20018874)		 ParkinsonsUK-UCL
CACAO		 PMID:20018874 MGI:4461115 NCBI chrNW_004955432:22,988,208...23,024,530
Ensembl chrNW_004955432:22,984,170...23,027,705 		JBrowse link
G R Wnt2 Wnt family member 2 involved_in ISO (PMID:20018874)
(MGI:4461115|PMID:20018874)		 RGD PMID:20018874 MGI:4461115 NCBI chr 4:46,328,408...46,374,673
Ensembl chr 4:46,333,998...46,374,402 		JBrowse link
G M Wnt2 wingless-type MMTV integration site family, member 2 involved_in IMP
ISO		 (MGI:4461115|PMID:20018874) CACAO
MGI		 PMID:20018874 GO_REF:0000119 MGI:4461115 MGI:4834177 NCBI chr 6:17,988,939...18,032,771
Ensembl chr 6:17,988,939...18,030,584 		JBrowse link
G H WNT2 Wnt family member 2 involved_in IEA
IDA		 (PMID:20018874) Ensembl
ParkinsonsUK-UCL		 PMID:20018874 GO_REF:0000107 NCBI chr 7:117,275,451...117,323,058
Ensembl chr 7:117,275,451...117,323,152 		JBrowse link
G N Wnt3a Wnt family member 3A involved_in ISO (MGI:2679774|PMID:14557550) ParkinsonsUK-UCL PMID:14557550 MGI:2679774 NCBI chrNW_004624937:816,752...845,866
Ensembl chrNW_004624937:816,759...845,458 		JBrowse link
G G WNT3A Wnt family member 3A involved_in ISO (MGI:2679774|PMID:14557550) ParkinsonsUK-UCL PMID:14557550 MGI:2679774 NCBI chr25:1,664,316...1,675,006
Ensembl chr25:1,666,053...1,719,881 		JBrowse link
G P WNT3A Wnt family member 3A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:51,153,978...51,203,678
Ensembl chr 2:51,153,970...51,202,176 		JBrowse link
G S Wnt3a Wnt family member 3A involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936864:150,742...179,205
Ensembl chrNW_004936864:150,732...192,423 		JBrowse link
G D WNT3A Wnt family member 3A involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:864,393...899,698
Ensembl chr14:863,424...896,412 		JBrowse link
G B WNT3A Wnt family member 3A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:203,409,294...203,463,214
Ensembl chr 1:208,628,706...208,674,469 		JBrowse link
G C Wnt3a Wnt family member 3A involved_in ISO (MGI:2679774|PMID:14557550) ParkinsonsUK-UCL PMID:14557550 MGI:2679774 NCBI chrNW_004955581:351,375...382,541
Ensembl chrNW_004955581:350,889...382,541 		JBrowse link
G R Wnt3a Wnt family member 3A involved_in ISO (MGI:2679774|PMID:14557550) RGD PMID:14557550 MGI:2679774 NCBI chr10:44,034,174...44,078,366
Ensembl chr10:44,034,194...44,078,324 		JBrowse link
G M Wnt3a wingless-type MMTV integration site family, member 3A involved_in IDA (MGI:2679774|PMID:14557550) ParkinsonsUK-UCL PMID:14557550 MGI:2679774 NCBI chr11:59,138,859...59,181,579
Ensembl chr11:59,138,859...59,181,578 		JBrowse link
G H WNT3A Wnt family member 3A involved_in TAS
IEA		 (PMID:24431302) ParkinsonsUK-UCL
Ensembl		 PMID:24431302 GO_REF:0000107 NCBI chr 1:228,006,998...228,061,271
Ensembl chr 1:228,006,998...228,061,271 		JBrowse link
negative regulation of cell proliferation in midbrain term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G N Wnt5a Wnt family member 5A involved_in ISO (MGI:3829860|PMID:18953410) ParkinsonsUK-UCL PMID:18953410 MGI:3829860 NCBI chrNW_004624822:1,824,378...1,843,599
Ensembl chrNW_004624822:1,825,238...1,841,288 		JBrowse link
G G WNT5A Wnt family member 5A involved_in ISO (MGI:3829860|PMID:18953410) ParkinsonsUK-UCL PMID:18953410 MGI:3829860 NCBI chr22:16,809,454...16,836,815
Ensembl chr22:16,809,451...16,825,048 		JBrowse link
G P WNT5A Wnt family member 5A involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:37,344,684...37,367,215
Ensembl chr13:37,344,699...37,367,207 		JBrowse link
G S Wnt5a Wnt family member 5A involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936473:6,031,627...6,052,211
Ensembl chrNW_004936473:6,029,976...6,052,159 		JBrowse link
G D WNT5A Wnt family member 5A involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:34,756,430...34,790,937
Ensembl chr20:34,769,930...34,786,673 		JBrowse link
G B WNT5A Wnt family member 5A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:55,396,279...55,418,579
Ensembl chr 3:56,621,380...56,638,051 		JBrowse link
G C Wnt5a Wnt family member 5A involved_in ISO (MGI:3829860|PMID:18953410) ParkinsonsUK-UCL PMID:18953410 MGI:3829860 NCBI chrNW_004955430:5,304,817...5,325,684
Ensembl chrNW_004955430:5,304,745...5,325,684 		JBrowse link
G R Wnt5a Wnt family member 5A involved_in ISO
IEA		 (MGI:3829860|PMID:18953410)
GO_REF:0000107		 RGD
Ensembl		 PMID:18953410 GO_REF:0000107 MGI:3829860 NCBI chr16:3,697,032...3,718,230
Ensembl chr16:3,697,032...3,718,234 		JBrowse link
G M Wnt5a wingless-type MMTV integration site family, member 5A involved_in IMP (MGI:3829860|PMID:18953410) ParkinsonsUK-UCL PMID:18953410 MGI:3829860 NCBI chr14:28,224,962...28,249,405
Ensembl chr14:28,226,707...28,249,405 		JBrowse link
G H WNT5A Wnt family member 5A involved_in NAS
IEA		 (PMID:24431302) ParkinsonsUK-UCL
Ensembl		 PMID:24431302 GO_REF:0000107 NCBI chr 3:55,465,715...55,505,263
Ensembl chr 3:55,465,715...55,490,539 		JBrowse link
positive regulation of cell proliferation in midbrain term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G N Pitx3 paired like homeodomain 3 ISO RGD PMID:18385323 RGD:11535083 NCBI chrNW_004624831:1,649,585...1,651,729
Ensembl chrNW_004624831:1,650,381...1,651,699 		JBrowse link
G G PITX3 paired like homeodomain 3 ISO RGD PMID:18385323 RGD:11535083 NCBI chr 9:95,266,257...95,278,333
Ensembl chr 9:95,266,582...95,268,139 		JBrowse link
G P PITX3 paired like homeodomain 3 ISO RGD PMID:18385323 RGD:11535083 NCBI chr14:113,230,194...113,241,393
Ensembl chr14:113,230,965...113,241,360 		JBrowse link
G S Pitx3 paired like homeodomain 3 ISO RGD PMID:18385323 RGD:11535083 NCBI chrNW_004936600:3,607,883...3,619,538
Ensembl chrNW_004936600:3,607,819...3,620,917 		JBrowse link
G D PITX3 paired like homeodomain 3 ISO RGD PMID:18385323 RGD:11535083 NCBI chr28:14,760,741...14,775,584
Ensembl chr28:14,761,094...14,762,716 		JBrowse link
G B PITX3 paired like homeodomain 3 ISO RGD PMID:18385323 RGD:11535083 NCBI chr10:98,833,330...98,846,292 JBrowse link
G C Pitx3 paired like homeodomain 3 ISO RGD PMID:18385323 RGD:11535083 NCBI chrNW_004955485:8,130,244...8,140,292
Ensembl chrNW_004955485:8,130,244...8,140,292 		JBrowse link
G R Pitx3 paired-like homeodomain 3 IDA RGD PMID:18385323 RGD:11535083 NCBI chr 1:245,001,106...245,013,881
Ensembl chr 1:245,001,164...245,013,892 		JBrowse link
G M Pitx3 paired-like homeodomain transcription factor 3 involved_in ISO RGD
MGI		 PMID:18385323 GO_REF:0000096 MGI:4417868 RGD:11535083 NCBI chr19:46,123,720...46,136,764
Ensembl chr19:46,124,124...46,136,765 		JBrowse link
G H PITX3 paired like homeodomain 3 involved_in ISO
IEA		 RGD
Ensembl		 PMID:18385323 GO_REF:0000107 RGD:11535083 NCBI chr10:102,230,189...102,241,512
Ensembl chr10:102,230,189...102,241,512 		JBrowse link
G N Ryk receptor like tyrosine kinase involved_in ISO PMID:23517308 ParkinsonsUK-UCL PMID:23517308 RGD:11054651 NCBI chrNW_004624730:10,462,590...10,568,780 JBrowse link
G G RYK receptor like tyrosine kinase involved_in ISO PMID:23517308 ParkinsonsUK-UCL PMID:23517308 RGD:11054651 NCBI chr15:56,127,048...56,217,407
Ensembl chr15:56,127,130...56,216,407 		JBrowse link
G P RYK receptor like tyrosine kinase involved_in ISO PMID:23517308 ParkinsonsUK-UCL PMID:23517308 RGD:11054651 NCBI chr13:75,285,482...75,390,314
Ensembl chr13:75,282,428...75,390,525 		JBrowse link
G S Ryk receptor like tyrosine kinase involved_in ISO PMID:23517308 ParkinsonsUK-UCL PMID:23517308 RGD:11054651 NCBI chrNW_004936529:7,273,070...7,344,372
Ensembl chrNW_004936529:7,273,097...7,332,468 		JBrowse link
G D RYK receptor like tyrosine kinase involved_in ISO PMID:23517308 ParkinsonsUK-UCL PMID:23517308 RGD:11054651 NCBI chr23:30,968,105...31,051,353
Ensembl chr23:30,968,231...31,051,605 		JBrowse link
G B RYK receptor like tyrosine kinase involved_in ISO PMID:23517308 ParkinsonsUK-UCL PMID:23517308 RGD:11054651 NCBI chr 3:131,174,507...131,296,815 JBrowse link
G C Ryk receptor like tyrosine kinase involved_in ISO PMID:23517308 ParkinsonsUK-UCL PMID:23517308 RGD:11054651 NCBI chrNW_004955501:4,360,051...4,419,083
Ensembl chrNW_004955501:4,328,682...4,419,307 		JBrowse link
G R Ryk receptor-like tyrosine kinase involved_in IMP PMID:23517308 ParkinsonsUK-UCL PMID:23517308 RGD:11054651 NCBI chr 8:103,419,338...103,492,083
Ensembl chr 8:103,419,275...103,491,698 		JBrowse link
G M Ryk receptor-like tyrosine kinase involved_in ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr 9:102,712,119...102,785,506
Ensembl chr 9:102,712,116...102,785,504 		JBrowse link
G H RYK receptor like tyrosine kinase involved_in IEA
ISS		 Ensembl
ParkinsonsUK-UCL		 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:134,157,133...134,250,859
Ensembl chr 3:134,065,303...134,250,859 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 181147
    developmental process 67218
      anatomical structure development 62958
        midbrain development 973
          cell proliferation in midbrain 80
            negative regulation of cell proliferation in midbrain 10
            positive regulation of cell proliferation in midbrain 20
            regulation of cell proliferation in midbrain + 30
Path 2
Term Annotations click to browse term
  biological_process 181147
    developmental process 67218
      anatomical structure development 62958
        multicellular organism development 50819
          system development 44165
            nervous system development 27508
              central nervous system development 11842
                brain development 8879
                  midbrain development 973
                    cell proliferation in midbrain 80
                      negative regulation of cell proliferation in midbrain 10
                      positive regulation of cell proliferation in midbrain 20
                      regulation of cell proliferation in midbrain + 30
paths to the root