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ONTOLOGY REPORT - ANNOTATIONS


Term:midbrain development
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Accession:GO:0030901 term browser browse the term
Definition:The process whose specific outcome is the progression of the midbrain over time, from its formation to the mature structure. The midbrain is the middle division of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes a ventral part containing the cerebral peduncles and a dorsal tectum containing the corpora quadrigemina and that surrounds the aqueduct of Sylvius connecting the third and fourth ventricles).
Synonyms:exact_synonym: mesencephalon development



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midbrain development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1c activin A receptor type 1C IEP RGD PMID:8940033 RGD:631880 NCBI chr 3:42,815,490...42,892,423
Ensembl chr 3:42,822,610...42,892,327
JBrowse link
G Aplp2 amyloid beta precursor like protein 2 acts_upstream_of_or_within ISO MGI:88059 (MGI:3577153|PMID:15689559) RGD PMID:15689559 MGI:3577153 NCBI chr 8:29,599,230...29,662,311
Ensembl chr 8:29,599,230...29,661,855
JBrowse link
G Barhl1 BarH-like homeobox 1 acts_upstream_of_or_within ISO MGI:2181383 (MGI:3708890|PMID:16752387) RGD PMID:16752387 MGI:3708890 NCBI chr 3:12,241,327...12,248,649
Ensembl chr 3:12,241,327...12,248,649
JBrowse link
G Cma1 chymase 1 IEP RGD PMID:21396433 RGD:5128663 NCBI chr15:29,417,451...29,420,233
Ensembl chr15:29,417,451...29,420,233
JBrowse link
G Ctnnb1 catenin beta 1 involved_in ISO (MGI:1931800|PMID:11262227) RGD PMID:11262227 MGI:1931800 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Cxcl6 C-X-C motif chemokine ligand 6 IEP RGD PMID:18436867 RGD:4892032 NCBI chr14:17,310,089...17,312,303
Ensembl chr14:17,310,426...17,313,093
JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 IEP RGD PMID:18436867 RGD:4892032 NCBI chr 9:75,729,493...75,735,868
Ensembl chr 9:75,729,115...75,739,425
JBrowse link
G Dlg5 discs large MAGUK scaffold protein 5 acts_upstream_of_or_within ISO MGI:3757646 (MGI:3722974|PMID:17765678) RGD PMID:17765678 MGI:3722974 NCBI chr15:75,786...209,735
Ensembl chr15:75,786...187,837
JBrowse link
G En1 engrailed homeobox 1 involved_in
acts_upstream_of_or_within
ISO UniProtKB:P04426 (MGI:82938|PMID:8848044)
MGI:95390 (MGI:3525936|PMID:15607945), (MGI:3578062|PMID:15175251)
RGD PMID:8848044 PMID:15175251 PMID:15607945 MGI:3525936 MGI:3578062 MGI:82938 NCBI chr13:31,750,892...31,756,477
Ensembl chr13:31,751,545...31,755,943
JBrowse link
G En2 engrailed homeobox 2 acts_upstream_of_or_within ISO MGI:95389 (MGI:3525936|PMID:15607945), (MGI:3578062|PMID:15175251) RGD PMID:15175251 PMID:15607945 MGI:3525936 MGI:3578062 NCBI chr 4:7,221,096...7,226,943
Ensembl chr 4:7,221,096...7,226,943
JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 acts_upstream_of_or_within ISO MGI:2448986|MGI:95523 (MGI:3719293|PMID:17687036) RGD PMID:17687036 MGI:3719293 NCBI chr16:66,492,445...66,546,731
Ensembl chr16:66,494,042...66,547,350
JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 acts_upstream_of_or_within ISO MGI:95522 (MGI:3719293|PMID:17687036) RGD PMID:17687036 MGI:3719293 NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626
JBrowse link
G Foxb1 forkhead box B1 involved_in ISS
ISO
GO_REF:0000024
(MGI:1931655|PMID:11170346)
UniProt
RGD
PMID:11170346 GO_REF:0000024 MGI:1931655 NCBI chr 8:70,407,221...70,409,841
Ensembl chr 8:70,408,186...70,409,781
JBrowse link
G Fzd3 frizzled class receptor 3 acts_upstream_of_or_within ISO MGI:108474 (MGI:4413542|PMID:19842188) RGD PMID:19842188 MGI:4413542 NCBI chr15:39,421,366...39,488,369
Ensembl chr15:39,421,355...39,488,369
JBrowse link
G Fzd6 frizzled class receptor 6 acts_upstream_of_or_within ISO MGI:108476 (MGI:4413542|PMID:19842188) RGD PMID:19842188 MGI:4413542 NCBI chr 7:70,055,012...70,086,781
Ensembl chr 7:70,055,068...70,086,776
JBrowse link
G Gdf7 growth differentiation factor 7 acts_upstream_of_or_within ISO MGI:2386906 (MGI:1353705|PMID:10693795) RGD PMID:10693795 MGI:1353705 NCBI chr 6:31,171,495...31,182,447
Ensembl chr 6:31,178,119...31,182,447
JBrowse link
G Gdnf glial cell derived neurotrophic factor IEP RGD PMID:16650834 RGD:2324945 NCBI chr 2:56,893,992...56,919,935
Ensembl chr 2:56,895,010...56,917,209
JBrowse link
G Hes1 hes family bHLH transcription factor 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:104877 (MGI:2149154|PMID:11500373)
Ensembl
RGD
PMID:11500373 GO_REF:0000107 MGI:2149154 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192
JBrowse link
G Hes3 hes family bHLH transcription factor 3 acts_upstream_of_or_within ISO MGI:104853 (MGI:2149154|PMID:11500373) RGD PMID:11500373 MGI:2149154 NCBI chr 5:162,793,611...162,799,578
Ensembl chr 5:162,794,367...162,796,261
JBrowse link
G Kat2a lysine acetyltransferase 2A acts_upstream_of_or_within ISO MGI:3711317 (MGI:3709911|PMID:17325035) RGD PMID:17325035 MGI:3709911 NCBI chr10:85,632,216...85,640,561
Ensembl chr10:85,632,216...85,640,166
JBrowse link
G Kdm2b lysine demethylase 2B involved_in ISO (MGI:4949568|PMID:21220025) RGD PMID:21220025 MGI:4949568 NCBI chr12:33,566,530...33,701,366
Ensembl chr12:33,574,657...33,701,355
JBrowse link
G Lmx1a LIM homeobox transcription factor 1 alpha acts_upstream_of_or_within ISO MGI:1888413 (MGI:5285997|PMID:21752929) RGD PMID:21752929 MGI:5285997 NCBI chr13:79,834,614...79,978,253
Ensembl chr13:79,835,019...79,978,253
JBrowse link
G Lmx1b LIM homeobox transcription factor 1 beta acts_upstream_of_or_within ISO MGI:2158463 (MGI:5285997|PMID:21752929) RGD PMID:21752929 MGI:5285997 NCBI chr 3:16,862,195...16,940,899
Ensembl chr 3:16,862,195...16,940,899
JBrowse link
G Lrp6 LDL receptor related protein 6 acts_upstream_of_or_within ISO MGI:2156191 (MGI:1891551|PMID:11029008) RGD PMID:11029008 MGI:1891551 NCBI chr 4:167,266,581...167,400,155
Ensembl chr 4:167,270,353...167,400,497
JBrowse link
G Msx1 msh homeobox 1 acts_upstream_of_or_within ISO MGI:1933766 (MGI:3046130|PMID:15188430) RGD PMID:15188430 MGI:3046130 NCBI chr14:72,961,170...72,964,970
Ensembl chr14:72,961,148...72,964,966
JBrowse link
G Ndst1 N-deacetylase and N-sulfotransferase 1 acts_upstream_of_or_within ISO MGI:98297 (MGI:3588476|PMID:16020517) RGD PMID:16020517 MGI:3588476 NCBI chr18:54,136,887...54,199,545
Ensembl chr18:54,140,779...54,178,191
JBrowse link
G Otx1 orthodenticle homeobox 1 acts_upstream_of_or_within ISO MGI:97451 (MGI:3045667|PMID:15201224), (MGI:4848254|PMID:20816794) RGD PMID:15201224 PMID:20816794 MGI:3045667 MGI:4848254 NCBI chr14:96,082,151...96,089,161
Ensembl chr14:96,082,151...96,089,086
JBrowse link
G Otx2 orthodenticle homeobox 2 acts_upstream_of_or_within ISO MGI:1857510|MGI:2176222|MGI:2661065|MGI:3046841|MGI:97450 (MGI:3045667|PMID:15201224), (MGI:3045668|PMID:15201223), (MGI:3578035|PMID:15888661), (MGI:4848254|PMID:20816794) RGD PMID:15201223 PMID:15201224 PMID:15888661 PMID:20816794 MGI:3045667 MGI:3045668 MGI:3578035 MGI:4848254 NCBI chr15:21,942,233...21,953,034
Ensembl chr15:21,943,191...21,953,416
JBrowse link
G Phox2a paired-like homeobox 2a involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:5285997|PMID:21752929)
Ensembl
RGD
PMID:21752929 GO_REF:0000107 MGI:5285997 NCBI chr 1:156,178,754...156,183,118
Ensembl chr 1:156,178,754...156,183,118
JBrowse link
G Pitx3 paired-like homeodomain 3 involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
MGI:1856667 (MGI:3035846|PMID:14973278), (MGI:3759093|PMID:17919745)
(MGI:3582099|PMID:15950611)
UniProt
RGD
PMID:14973278 PMID:15950611 PMID:17919745 GO_REF:0000024 MGI:3035846 MGI:3582099 MGI:3759093 NCBI chr 1:245,001,106...245,013,881
Ensembl chr 1:245,001,164...245,013,892
JBrowse link
G Rfx4 regulatory factor X4 acts_upstream_of_or_within ISO (MGI:2669568|PMID:12925582) RGD PMID:12925582 MGI:2669568 NCBI chr 7:18,853,065...19,015,378
Ensembl chr 7:18,853,322...19,014,967
JBrowse link
G Shh sonic hedgehog signaling molecule involved_in
acts_upstream_of_or_within
IEA
ISO
ISS
GO_REF:0000107
MGI:104719 (MGI:3588476|PMID:16020517)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:16020517 GO_REF:0000024 GO_REF:0000107 MGI:3588476 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170
JBrowse link
G Smad1 SMAD family member 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2157982 (MGI:3581106|PMID:15899870)
Ensembl
RGD
PMID:15899870 GO_REF:0000107 MGI:3581106 NCBI chr19:28,513,130...28,573,665
Ensembl chr19:28,513,131...28,573,651
JBrowse link
G Smad9 SMAD family member 9 acts_upstream_of_or_within
involved_in
ISO
IEA
MGI:3581766 (MGI:3581106|PMID:15899870)
GO_REF:0000107
RGD
Ensembl
PMID:15899870 GO_REF:0000107 MGI:3581106 NCBI chr 2:138,956,326...139,006,315
Ensembl chr 2:138,986,471...139,006,307
JBrowse link
G Taf1 TATA-box binding protein associated factor 1 involved_in ISO UniProtKB:Q1LYC2 (PMID:26637982) RGD PMID:26637982 NCBI chr  X:66,640,915...66,716,543
Ensembl chr  X:66,640,982...66,716,543
JBrowse link
G Tal2 TAL bHLH transcription factor 2 acts_upstream_of_or_within ISO MGI:2684532 (MGI:1927272|PMID:11071772) RGD PMID:11071772 MGI:1927272 NCBI chr 5:68,411,012...68,417,569
Ensembl chr 5:68,411,012...68,417,569
JBrowse link
G Uchl5 ubiquitin C-terminal hydrolase L5 involved_in ISO (MGI:4849324|PMID:21048919) RGD PMID:21048919 MGI:4849324 NCBI chr13:55,520,722...55,556,503
Ensembl chr13:55,520,729...55,556,502
JBrowse link
G Uqcrq ubiquinol-cytochrome c reductase, complex III subunit VII acts_upstream_of_or_within ISO (PMID:16901643) RGD PMID:16901643 NCBI chr10:37,585,864...37,589,328
Ensembl chr10:37,586,888...37,589,169
JBrowse link
G Wls Wnt ligand secretion mediator involved_in ISO (MGI:4834980|PMID:20614471) RGD PMID:20614471 MGI:4834980 NCBI chr 2:248,931,885...249,047,248
Ensembl chr 2:248,931,903...249,048,298
JBrowse link
G Wnt1 Wnt family member 1 acts_upstream_of_or_within
involved_in
ISO MGI:1857490 (MGI:59176|PMID:2205396)
(MGI:1931348|PMID:2202907), (MGI:2679774|PMID:14557550), (MGI:82938|PMID:8848044)
RGD PMID:2202907 PMID:2205396 PMID:8848044 PMID:14557550 MGI:1931348 MGI:2679774 MGI:59176 MGI:82938 NCBI chr 7:129,938,604...129,942,651
Ensembl chr 7:129,938,604...129,942,651
JBrowse link
G Wnt3a Wnt family member 3A involved_in ISO (MGI:2679774|PMID:14557550) RGD PMID:14557550 MGI:2679774 NCBI chr10:44,034,174...44,078,463
Ensembl chr10:44,034,194...44,078,324
JBrowse link
G Wnt5a Wnt family member 5A involved_in ISO UniProtKB:P04426 (MGI:2679774|PMID:14557550), (MGI:5469218|PMID:23324743) RGD PMID:14557550 PMID:23324743 MGI:2679774 MGI:5469218 NCBI chr16:3,695,667...3,718,234
Ensembl chr16:3,697,032...3,718,234
JBrowse link
canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt1 Wnt family member 1 involved_in ISO (MGI:5705221|PMID:19951692) RGD PMID:19951692 MGI:5705221 NCBI chr 7:129,938,604...129,942,651
Ensembl chr 7:129,938,604...129,942,651
JBrowse link
G Wnt2 Wnt family member 2 involved_in ISO (PMID:20018874) RGD PMID:20018874 NCBI chr 4:46,328,408...46,374,673
Ensembl chr 4:46,333,998...46,374,402
JBrowse link
G Wnt3 Wnt family member 3 involved_in ISO (PMID:25640183) RGD PMID:25640183 NCBI chr10:88,680,248...88,724,170
Ensembl chr10:88,680,248...88,724,099
JBrowse link
cell proliferation in midbrain term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fzd3 frizzled class receptor 3 acts_upstream_of_or_within ISO MGI:108474 (MGI:4413542|PMID:19842188) RGD PMID:19842188 MGI:4413542 NCBI chr15:39,421,366...39,488,369
Ensembl chr15:39,421,355...39,488,369
JBrowse link
G Fzd6 frizzled class receptor 6 acts_upstream_of_or_within ISO MGI:108476 (MGI:4413542|PMID:19842188) RGD PMID:19842188 MGI:4413542 NCBI chr 7:70,055,012...70,086,781
Ensembl chr 7:70,055,068...70,086,776
JBrowse link
G Wnt1 Wnt family member 1 involved_in ISO (MGI:2679774|PMID:14557550), (MGI:3045659|PMID:15121182) RGD PMID:14557550 PMID:15121182 MGI:2679774 MGI:3045659 NCBI chr 7:129,938,604...129,942,651
Ensembl chr 7:129,938,604...129,942,651
JBrowse link
G Wnt2 Wnt family member 2 involved_in ISO (PMID:20018874)
(MGI:4461115|PMID:20018874)
RGD PMID:20018874 MGI:4461115 NCBI chr 4:46,328,408...46,374,673
Ensembl chr 4:46,333,998...46,374,402
JBrowse link
G Wnt3a Wnt family member 3A involved_in ISO (MGI:2679774|PMID:14557550) RGD PMID:14557550 MGI:2679774 NCBI chr10:44,034,174...44,078,463
Ensembl chr10:44,034,194...44,078,324
JBrowse link
inferior colliculus development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxb1 forkhead box B1 involved_in ISS
ISO
GO_REF:0000024
(MGI:1931655|PMID:11170346)
UniProt
RGD
PMID:11170346 GO_REF:0000024 MGI:1931655 NCBI chr 8:70,407,221...70,409,841
Ensembl chr 8:70,408,186...70,409,781
JBrowse link
G Tfap2d transcription factor AP-2 delta acts_upstream_of_or_within ISO MGI:5296818 (MGI:5295521|PMID:21858141) RGD PMID:21858141 MGI:5295521 NCBI chr 9:21,680,157...21,744,840
Ensembl chr 9:21,680,577...21,740,728
JBrowse link
midbrain dopaminergic neuron differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctnnb1 catenin beta 1 involved_in IEA
ISO
GO_REF:0000107
(MGI:3836885|PMID:19122665)
Ensembl
RGD
PMID:19122665 GO_REF:0000107 MGI:3836885 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Lmx1a LIM homeobox transcription factor 1 alpha involved_in ISO (MGI:5705221|PMID:19951692) RGD PMID:19951692 MGI:5705221 NCBI chr13:79,834,614...79,978,253
Ensembl chr13:79,835,019...79,978,253
JBrowse link
G Rac1 Rac family small GTPase 1 involved_in ISO (MGI:3829860|PMID:18953410), (MGI:5466648|PMID:23109420) RGD PMID:18953410 PMID:23109420 MGI:3829860 MGI:5466648 NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251
JBrowse link
G Ryk receptor-like tyrosine kinase involved_in ISO (MGI:5707582|PMID:23517308) RGD PMID:23517308 MGI:5707582 NCBI chr 8:103,419,348...103,492,083
Ensembl chr 8:103,419,275...103,491,698
JBrowse link
G Wnt1 Wnt family member 1 involved_in ISO (MGI:5469218|PMID:23324743) RGD PMID:23324743 MGI:5469218 NCBI chr 7:129,938,604...129,942,651
Ensembl chr 7:129,938,604...129,942,651
JBrowse link
G Wnt2 Wnt family member 2 involved_in ISO (PMID:20018874) RGD PMID:20018874 NCBI chr 4:46,328,408...46,374,673
Ensembl chr 4:46,333,998...46,374,402
JBrowse link
G Wnt5a Wnt family member 5A involved_in ISO UniProtKB:P04426 (MGI:2679774|PMID:14557550), (MGI:3829860|PMID:18953410), (MGI:5469218|PMID:23324743), (MGI:5700308|PMID:15748172) RGD PMID:14557550 PMID:15748172 PMID:18953410 PMID:23324743 MGI:2679774 MGI:3829860 MGI:5469218 MGI:5700308 NCBI chr16:3,695,667...3,718,234
Ensembl chr16:3,697,032...3,718,234
JBrowse link
G Wnt9b Wnt family member 9B involved_in ISO (PMID:25640183) RGD PMID:25640183 NCBI chr10:88,635,330...88,657,035
Ensembl chr10:88,635,331...88,657,035
JBrowse link
midbrain morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sos1 SOS Ras/Rac guanine nucleotide exchange factor 1 acts_upstream_of_or_within ISO MGI:2155441 (MGI:85697|PMID:9030684) RGD PMID:9030684 MGI:85697 NCBI chr 6:14,533,870...14,613,348
Ensembl chr 6:14,533,360...14,611,107
JBrowse link
negative regulation of cell proliferation in midbrain term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt5a Wnt family member 5A involved_in ISO (MGI:3829860|PMID:18953410) RGD PMID:18953410 MGI:3829860 NCBI chr16:3,695,667...3,718,234
Ensembl chr16:3,697,032...3,718,234
JBrowse link
non-canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt9b Wnt family member 9B involved_in ISO (PMID:25640183) RGD PMID:25640183 NCBI chr10:88,635,330...88,657,035
Ensembl chr10:88,635,331...88,657,035
JBrowse link
positive regulation of cell proliferation in midbrain term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pitx3 paired-like homeodomain 3 IDA RGD PMID:18385323 RGD:11535083 NCBI chr 1:245,001,106...245,013,881
Ensembl chr 1:245,001,164...245,013,892
JBrowse link
positive regulation of midbrain dopaminergic neuron differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 involved_in ISO (MGI:4948425|PMID:21347250) RGD PMID:21347250 MGI:4948425 NCBI chr 1:228,381,521...228,385,202
Ensembl chr 1:228,381,521...228,385,202
JBrowse link
positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Csnk1e casein kinase 1, epsilon involved_in NAS PMID:17244647 ParkinsonsUK-UCL PMID:17244647 RGD:10448953 NCBI chr 7:110,983,322...111,006,926
Ensembl chr 7:110,983,318...111,006,794
JBrowse link
regulation of midbrain dopaminergic neuron differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sfrp1 secreted frizzled-related protein 1 involved_in IEA
ISO
GO_REF:0000107
UniProtKB:P97299 (MGI:5448935|PMID:22290867)
Ensembl
RGD
PMID:22290867 GO_REF:0000107 MGI:5448935 NCBI chr16:68,575,763...68,613,905
Ensembl chr16:68,575,763...68,614,286
JBrowse link
G Sfrp2 secreted frizzled-related protein 2 involved_in ISO UniProtKB:Q8C4U3 (MGI:5448935|PMID:22290867) RGD PMID:22290867 MGI:5448935 NCBI chr 2:169,089,517...169,097,064
Ensembl chr 2:169,089,517...169,097,063
JBrowse link
substantia nigra development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actb actin, beta involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877
JBrowse link
G Atp5pb ATP synthase peripheral stalk-membrane subunit b involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr 2:193,424,138...193,435,418
Ensembl chr 2:193,424,047...193,435,418
JBrowse link
G Atp5pf ATP synthase peripheral stalk subunit F6 involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr11:23,881,594...23,889,581
Ensembl chr11:23,881,592...23,889,119
JBrowse link
G Basp1 brain abundant, membrane attached signal protein 1 involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr 2:75,816,130...75,863,801
Ensembl chr 2:75,816,122...75,864,043
JBrowse link
G Calm1 calmodulin 1 involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr 6:119,487,691...119,495,759
Ensembl chr 6:119,487,621...119,498,227
JBrowse link
G Calm2 calmodulin 2 involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr 6:7,091,624...7,104,284
Ensembl chr 6:7,091,567...7,104,287
JBrowse link
G Calm3 calmodulin 3 involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr 1:77,590,668...77,597,776
Ensembl chr 1:77,589,230...77,592,207
JBrowse link
G Ccdc14 coiled-coil domain containing 14 involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr11:66,052,063...66,087,915
Ensembl chr11:66,052,620...66,087,956
JBrowse link
G Cdc42 cell division cycle 42 involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr 5:149,555,069...149,593,239
Ensembl chr 5:149,553,724...149,593,111
JBrowse link
G Ckb creatine kinase B involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr 6:130,729,420...130,732,301
Ensembl chr 6:130,729,423...130,732,315
JBrowse link
G Cnp 2',3'-cyclic nucleotide 3' phosphodiesterase involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr10:85,511,164...85,517,723
Ensembl chr10:85,511,160...85,517,720
JBrowse link
G Cox6b1 cytochrome c oxidase subunit 6B1 involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr 1:85,875,080...85,884,081
Ensembl chr 1:85,875,109...85,884,001
JBrowse link
G Dynll1 dynein light chain LC8-type 1 involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr12:41,312,367...41,314,742
Ensembl chr12:41,312,367...41,314,741
JBrowse link
G Eno3 enolase 3 involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr10:55,370,531...55,375,921
Ensembl chr10:55,366,975...55,375,921
JBrowse link
G Fgf2 fibroblast growth factor 2 acts_upstream_of_or_within ISO MGI:1857458 (MGI:3696489|PMID:17234579) RGD PMID:17234579 MGI:3696489 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221
JBrowse link
G Fgf9 fibroblast growth factor 9 involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr15:32,208,993...32,254,952
Ensembl chr15:32,210,074...32,253,309
JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 acts_upstream_of_or_within ISO MGI:1931521 (MGI:3696489|PMID:17234579) RGD PMID:17234579 MGI:3696489 NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801
JBrowse link
G Glud1 glutamate dehydrogenase 1 involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr16:9,640,312...9,673,961
Ensembl chr16:9,640,312...9,673,957
JBrowse link
G Gnb4 G protein subunit beta 4 involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr 2:115,360,746...115,400,680
Ensembl chr 2:115,364,918...115,400,579
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
JBrowse link
G Ina internexin neuronal intermediate filament protein, alpha involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr 1:245,896,775...245,908,330
Ensembl chr 1:245,896,775...245,908,330
JBrowse link
G Ldha lactate dehydrogenase A involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr 1:97,371,823...97,381,247
Ensembl chr 1:97,366,021...97,433,472
JBrowse link
G Mag myelin-associated glycoprotein involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr 1:86,148,227...86,163,726
Ensembl chr 1:86,148,228...86,163,656
JBrowse link
G Maob monoamine oxidase B involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr  X:5,907,327...6,010,996
Ensembl chr  X:5,907,266...6,011,003
JBrowse link
G Mapkap1 MAPK associated protein 1 involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr 3:17,715,813...17,918,387
Ensembl chr 3:17,715,834...17,918,384
JBrowse link
G Mbp myelin basic protein involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr18:75,855,878...75,966,404
Ensembl chr18:75,855,878...75,966,404
JBrowse link
G Ndrg2 NDRG family member 2 involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr15:24,600,981...24,609,621
Ensembl chr15:24,600,982...24,609,626
JBrowse link
G Ndufs3 NADH:ubiquinone oxidoreductase core subunit S3 involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr 3:76,876,646...76,883,824
Ensembl chr 3:76,876,646...76,883,824
JBrowse link
G Padi2 peptidyl arginine deiminase 2 involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr 5:153,209,053...153,251,632
Ensembl chr 5:153,209,053...153,251,632
JBrowse link
G Plp1 proteolipid protein 1 involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr  X:100,184,039...100,201,035
Ensembl chr  X:100,185,767...100,201,032
JBrowse link
G Rad1 RAD1 checkpoint DNA exonuclease involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr 2:59,461,597...59,469,707
Ensembl chr 2:59,461,607...59,469,689
JBrowse link
G Rhoa ras homolog family member A involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746
JBrowse link
G S100a1 S100 calcium binding protein A1 involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr 2:175,993,922...175,998,765
Ensembl chr 2:175,993,922...175,999,544
JBrowse link
G Sec16a SEC16 homolog A, endoplasmic reticulum export factor involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr 3:9,229,687...9,264,837
Ensembl chr 3:9,229,687...9,264,273
JBrowse link
G Sirt2 sirtuin 2 involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr 1:84,053,883...84,076,975
Ensembl chr 1:84,052,903...84,076,975
JBrowse link
G Suds3 SDS3 homolog, SIN3A corepressor complex component involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr12:39,477,181...39,499,633
Ensembl chr12:39,477,568...39,499,628
JBrowse link
G Syngr3 synaptogyrin 3 involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr10:13,710,553...13,715,312
Ensembl chr10:13,704,998...13,715,669
JBrowse link
G Sypl2 synaptophysin-like 2 involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr 2:195,849,062...195,863,794
Ensembl chr 2:195,849,062...195,863,794
JBrowse link
G Ttbk1 tau tubulin kinase 1 involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr 9:14,493,166...14,538,372
Ensembl chr 9:14,493,389...14,535,774
JBrowse link
G Uchl1 ubiquitin C-terminal hydrolase L1 involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr14:41,485,033...41,495,590
Ensembl chr14:41,485,031...41,495,590
JBrowse link
G Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr10:60,584,665...60,622,352
Ensembl chr10:60,584,652...60,671,589
JBrowse link
G Ywhah tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr14:77,696,332...77,705,715
Ensembl chr14:77,696,333...77,705,741
JBrowse link
G Ywhaq tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr 6:40,935,714...40,966,240
Ensembl chr 6:40,935,949...40,966,273
JBrowse link
G Zfp148 zinc finger protein 148 involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr11:67,276,455...67,385,803
Ensembl chr11:67,281,707...67,385,772
JBrowse link
Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt5a Wnt family member 5A involved_in ISO (MGI:5707582|PMID:23517308) RGD PMID:23517308 MGI:5707582 NCBI chr16:3,695,667...3,718,234
Ensembl chr16:3,697,032...3,718,234
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19512
    developmental process 6931
      anatomical structure development 6346
        midbrain development 98
          cell proliferation in midbrain + 7
          corpora quadrigemina development + 2
          midbrain dopaminergic neuron differentiation + 13
          midbrain morphogenesis 1
          substantia nigra development 45
          ventral tegmental area development 0
Path 2
Term Annotations click to browse term
  biological_process 19512
    developmental process 6931
      anatomical structure development 6346
        multicellular organism development 5773
          system development 5413
            nervous system development 2747
              central nervous system development 1281
                brain development 983
                  midbrain development 98
                    cell proliferation in midbrain + 7
                    corpora quadrigemina development + 2
                    midbrain dopaminergic neuron differentiation + 13
                    midbrain morphogenesis 1
                    substantia nigra development 45
                    ventral tegmental area development 0
paths to the root