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ONTOLOGY REPORT - ANNOTATIONS


Term:midbrain development
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Accession:GO:0030901 term browser browse the term
Definition:The process whose specific outcome is the progression of the midbrain over time, from its formation to the mature structure. The midbrain is the middle division of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes a ventral part containing the cerebral peduncles and a dorsal tectum containing the corpora quadrigemina and that surrounds the aqueduct of Sylvius connecting the third and fourth ventricles).
Synonyms:exact_synonym: mesencephalon development


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midbrain development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1c activin A receptor type 1C IEP RGD PMID:8940033 RGD:631880 NCBI chr 3:44,272,859...44,342,501
Ensembl chr 3:44,270,653...44,342,355
JBrowse link
G Aplp2 amyloid beta precursor like protein 2 acts_upstream_of_or_within ISO MGI:88059 (MGI:3577153|PMID:15689559) RGD PMID:15689559 MGI:3577153 NCBI chr 8:32,298,526...32,328,821
Ensembl chr 8:32,298,532...32,328,839
JBrowse link
G Barhl1 BarH-like homeobox 1 acts_upstream_of_or_within ISO MGI:2181383 (MGI:3708890|PMID:16752387) RGD PMID:16752387 MGI:3708890 NCBI chr 3:7,491,234...7,498,555
Ensembl chr 3:7,491,234...7,498,555
JBrowse link
G Cma1 chymase 1 IEP RGD PMID:21396433 RGD:5128663 NCBI chr15:34,601,037...34,603,819
Ensembl chr15:34,601,037...34,603,819
JBrowse link
G Ctnnb1 catenin beta 1 involved_in ISO (MGI:1931800|PMID:11262227) RGD PMID:11262227 MGI:1931800 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Cxcl6 C-X-C motif chemokine ligand 6 IEP RGD PMID:18436867 RGD:4892032 NCBI chr14:18,860,201...18,920,839
Ensembl chr14:18,860,264...18,862,407
JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 IEP RGD PMID:18436867 RGD:4892032 NCBI chr 9:81,427,275...81,435,065
Ensembl chr 9:81,427,730...81,434,102
JBrowse link
G Dlg5 discs large MAGUK scaffold protein 5 acts_upstream_of_or_within ISO MGI:3757646 (MGI:3722974|PMID:17765678) RGD PMID:17765678 MGI:3722974 NCBI chr15:120,213...230,312
Ensembl chr15:120,372...228,977
JBrowse link
G En1 engrailed homeobox 1 involved_in
acts_upstream_of_or_within
ISO UniProtKB:P04426 (MGI:82938|PMID:8848044)
MGI:95390 (MGI:3525936|PMID:15607945), (MGI:3578062|PMID:15175251)
RGD PMID:8848044 PMID:15175251 PMID:15607945 MGI:3525936 MGI:3578062 MGI:82938 NCBI chr13:36,532,758...36,537,888
Ensembl chr13:36,532,758...36,537,093
JBrowse link
G En2 engrailed homeobox 2 acts_upstream_of_or_within ISO MGI:95389 (MGI:3525936|PMID:15607945), (MGI:3578062|PMID:15175251) RGD PMID:15175251 PMID:15607945 MGI:3525936 MGI:3578062 NCBI chr 4:438,668...444,508
Ensembl chr 4:438,668...444,501
JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 acts_upstream_of_or_within ISO MGI:2448986|MGI:95523 (MGI:3719293|PMID:17687036) RGD PMID:17687036 MGI:3719293 NCBI chr16:71,265,390...71,319,046
Ensembl chr16:71,266,248...71,319,449
JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 acts_upstream_of_or_within ISO MGI:95522 (MGI:3719293|PMID:17687036) RGD PMID:17687036 MGI:3719293 NCBI chr 1:200,590,951...200,696,946
Ensembl chr 1:200,590,953...200,696,928
JBrowse link
G Foxb1 forkhead box B1 involved_in ISS
ISO
GO_REF:0000024
(MGI:1931655|PMID:11170346)
UniProt
RGD
PMID:11170346 GO_REF:0000024 MGI:1931655 NCBI chr 8:75,992,751...75,995,371
Ensembl chr 8:75,992,755...75,995,371
JBrowse link
G Fzd3 frizzled class receptor 3 acts_upstream_of_or_within ISO MGI:108474 (MGI:4413542|PMID:19842188) RGD PMID:19842188 MGI:4413542 NCBI chr15:48,601,259...48,670,257
Ensembl chr15:48,601,266...48,670,257
JBrowse link
G Fzd6 frizzled class receptor 6 acts_upstream_of_or_within ISO MGI:108476 (MGI:4413542|PMID:19842188) RGD PMID:19842188 MGI:4413542 NCBI chr 7:77,898,329...77,931,034
Ensembl chr 7:77,899,322...77,931,029
JBrowse link
G Gdf7 growth differentiation factor 7 acts_upstream_of_or_within ISO MGI:2386906 (MGI:1353705|PMID:10693795) RGD PMID:10693795 MGI:1353705 NCBI chr 6:33,496,596...33,507,626
Ensembl chr 6:33,503,217...33,507,542
JBrowse link
G Gdnf glial cell derived neurotrophic factor IEP RGD PMID:16650834 RGD:2324945 NCBI chr 2:56,884,181...56,912,964
Ensembl chr 2:56,887,987...56,910,238
JBrowse link
G Hes1 hes family bHLH transcription factor 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:104877 (MGI:2149154|PMID:11500373)
Ensembl
RGD
PMID:11500373 GO_REF:0000107 MGI:2149154 NCBI chr11:74,312,837...74,315,249
Ensembl chr11:74,312,806...74,315,248
JBrowse link
G Hes3 hes family bHLH transcription factor 3 acts_upstream_of_or_within ISO MGI:104853 (MGI:2149154|PMID:11500373) RGD PMID:11500373 MGI:2149154 NCBI chr 5:169,463,196...169,469,795
Ensembl chr 5:169,464,989...169,467,153
JBrowse link
G Kat2a lysine acetyltransferase 2A acts_upstream_of_or_within ISO MGI:3711317 (MGI:3709911|PMID:17325035) RGD PMID:17325035 MGI:3709911 NCBI chr10:88,611,586...88,619,558
Ensembl chr10:88,611,586...88,619,537
JBrowse link
G Kdm2b lysine demethylase 2B involved_in ISO (MGI:4949568|PMID:21220025) RGD PMID:21220025 MGI:4949568 NCBI chr12:39,021,924...39,161,954
Ensembl chr12:39,078,119...39,161,956
JBrowse link
G Lmx1a LIM homeobox transcription factor 1 alpha acts_upstream_of_or_within ISO MGI:1888413 (MGI:5285997|PMID:21752929) RGD PMID:21752929 MGI:5285997 NCBI chr13:85,916,753...86,061,534
Ensembl chr13:85,918,252...86,061,176
JBrowse link
G Lmx1b LIM homeobox transcription factor 1 beta acts_upstream_of_or_within ISO MGI:2158463 (MGI:5285997|PMID:21752929) RGD PMID:21752929 MGI:5285997 NCBI chr 3:12,608,748...12,686,937
Ensembl chr 3:12,609,574...12,686,869
JBrowse link
G Lrp6 LDL receptor related protein 6 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:2156191 (MGI:1891551|PMID:11029008)
RGD PMID:11029008, PMID:21873635 MGI:1891551, RGD:13792537 NCBI chr 4:168,194,054...168,323,962
Ensembl chr 4:168,194,927...168,323,751
JBrowse link
G Msx1 msh homeobox 1 acts_upstream_of_or_within ISO MGI:1933766 (MGI:3046130|PMID:15188430) RGD PMID:15188430 MGI:3046130 NCBI chr14:77,712,262...77,716,061
Ensembl chr14:77,712,240...77,716,059
JBrowse link
G Ndst1 N-deacetylase and N-sulfotransferase 1 acts_upstream_of_or_within ISO MGI:98297 (MGI:3588476|PMID:16020517) RGD PMID:16020517 MGI:3588476 NCBI chr18:55,951,497...56,014,107
Ensembl chr18:55,955,389...55,992,885
JBrowse link
G Otx1 orthodenticle homeobox 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:97451 (MGI:3045667|PMID:15201224), (MGI:4848254|PMID:20816794)
Ensembl
RGD
PMID:15201224 PMID:20816794 GO_REF:0000107 MGI:3045667 MGI:4848254 NCBI chr14:106,861,556...106,864,933
Ensembl chr14:106,861,676...106,864,892
JBrowse link
G Otx2 orthodenticle homeobox 2 acts_upstream_of_or_within ISO MGI:1857510|MGI:2176222|MGI:2661065|MGI:3046841|MGI:97450 (MGI:3045667|PMID:15201224), (MGI:3045668|PMID:15201223), (MGI:3578035|PMID:15888661), (MGI:4848254|PMID:20816794) RGD PMID:15201223 PMID:15201224 PMID:15888661 PMID:20816794 MGI:3045667 MGI:3045668 MGI:3578035 MGI:4848254 NCBI chr15:25,500,037...25,511,619
Ensembl chr15:25,502,019...25,505,691
Ensembl chr15:25,502,019...25,505,691
JBrowse link
G Phox2a paired-like homeobox 2a involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:5285997|PMID:21752929)
Ensembl
RGD
PMID:21752929 GO_REF:0000107 MGI:5285997 NCBI chr 1:166,893,734...166,898,252
Ensembl chr 1:166,893,734...166,898,252
JBrowse link
G Pitx3 paired-like homeodomain 3 involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
MGI:1856667 (MGI:3035846|PMID:14973278), (MGI:3759093|PMID:17919745)
(MGI:3582099|PMID:15950611)
UniProt
RGD
PMID:14973278 PMID:15950611 PMID:17919745 GO_REF:0000024 MGI:3035846 MGI:3582099 MGI:3759093 NCBI chr 1:265,886,766...265,899,947
Ensembl chr 1:265,887,230...265,899,958
JBrowse link
G Rfx4 regulatory factor X4 acts_upstream_of_or_within ISO (MGI:2669568|PMID:12925582) RGD PMID:12925582 MGI:2669568 NCBI chr 7:25,831,358...25,909,976
Ensembl chr 7:25,808,419...25,907,849
JBrowse link
G Shh sonic hedgehog signaling molecule involved_in
acts_upstream_of_or_within
IEA
ISO
ISS
GO_REF:0000107
MGI:104719 (MGI:3588476|PMID:16020517)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:16020517 GO_REF:0000024 GO_REF:0000107 MGI:3588476 NCBI chr 4:718,538...727,691
Ensembl chr 4:718,538...727,691
JBrowse link
G Smad1 SMAD family member 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2157982 (MGI:3581106|PMID:15899870)
Ensembl
RGD
PMID:15899870 GO_REF:0000107 MGI:3581106 NCBI chr19:32,182,942...32,248,694
Ensembl chr19:32,188,267...32,248,684
JBrowse link
G Smad9 SMAD family member 9 acts_upstream_of_or_within ISO MGI:3581766 (MGI:3581106|PMID:15899870) RGD PMID:15899870 MGI:3581106 NCBI chr 2:143,951,725...144,002,025
Ensembl chr 2:144,191,846...144,212,138
Ensembl chr 2:144,191,846...144,212,138
JBrowse link
G Taf1 TATA-box binding protein associated factor 1 involved_in ISO UniProtKB:Q1LYC2 (PMID:26637982) RGD PMID:26637982 NCBI chr  X:71,412,291...71,486,456
Ensembl chr  X:71,412,289...71,485,085
JBrowse link
G Tal2 TAL bHLH transcription factor 2 acts_upstream_of_or_within ISO MGI:2684532 (MGI:1927272|PMID:11071772) RGD PMID:11071772 MGI:1927272 NCBI chr 5:70,592,871...70,599,428
Ensembl chr 5:70,592,871...70,599,428
JBrowse link
G Uchl5 ubiquitin C-terminal hydrolase L5 involved_in ISO (MGI:4849324|PMID:21048919) RGD PMID:21048919 MGI:4849324 NCBI chr13:60,568,102...60,603,812
Ensembl chr13:60,545,635...60,603,811
JBrowse link
G Uqcrq ubiquinol-cytochrome c reductase, complex III subunit VII acts_upstream_of_or_within ISO (PMID:16901643) RGD PMID:16901643 NCBI chr10:38,779,132...38,782,489
Ensembl chr10:38,779,132...38,782,419
JBrowse link
G Wls Wnt ligand secretion mediator involved_in ISO (MGI:4834980|PMID:20614471) RGD PMID:20614471 MGI:4834980 NCBI chr 2:266,315,036...266,431,220
Ensembl chr 2:266,315,036...266,432,558
JBrowse link
G Wnt1 Wnt family member 1 acts_upstream_of_or_within
involved_in
ISO MGI:1857490 (MGI:59176|PMID:2205396)
(MGI:1931348|PMID:2202907), (MGI:2679774|PMID:14557550), (MGI:82938|PMID:8848044)
RGD PMID:2202907 PMID:2205396 PMID:8848044 PMID:14557550 MGI:1931348 MGI:2679774 MGI:59176 MGI:82938 NCBI chr 7:140,464,999...140,469,046
Ensembl chr 7:140,464,999...140,469,046
JBrowse link
G Wnt3a Wnt family member 3A involved_in ISO (MGI:2679774|PMID:14557550) RGD PMID:14557550 MGI:2679774 NCBI chr10:45,598,898...45,643,151
Ensembl chr10:45,598,912...45,638,035
JBrowse link
G Wnt5a Wnt family member 5A involved_in ISO UniProtKB:P04426 (MGI:2679774|PMID:14557550), (MGI:5469218|PMID:23324743) RGD PMID:14557550 PMID:23324743 MGI:2679774 MGI:5469218 NCBI chr16:4,469,451...4,490,271
Ensembl chr16:4,469,468...4,489,860
JBrowse link
canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt1 Wnt family member 1 involved_in ISO (MGI:5705221|PMID:19951692) RGD PMID:19951692 MGI:5705221 NCBI chr 7:140,464,999...140,469,046
Ensembl chr 7:140,464,999...140,469,046
JBrowse link
G Wnt2 Wnt family member 2 involved_in ISO (PMID:20018874) RGD PMID:20018874 NCBI chr 4:45,286,845...45,332,899
Ensembl chr 4:45,292,437...45,332,420
JBrowse link
G Wnt3 Wnt family member 3 involved_in IEA
ISO
GO_REF:0000107
(PMID:25640183)
Ensembl
RGD
PMID:25640183 GO_REF:0000107 NCBI chr10:91,830,709...91,874,907
Ensembl chr10:91,830,654...91,874,793
JBrowse link
cell proliferation in midbrain term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fzd3 frizzled class receptor 3 acts_upstream_of_or_within ISO MGI:108474 (MGI:4413542|PMID:19842188) RGD PMID:19842188 MGI:4413542 NCBI chr15:48,601,259...48,670,257
Ensembl chr15:48,601,266...48,670,257
JBrowse link
G Fzd6 frizzled class receptor 6 acts_upstream_of_or_within ISO MGI:108476 (MGI:4413542|PMID:19842188) RGD PMID:19842188 MGI:4413542 NCBI chr 7:77,898,329...77,931,034
Ensembl chr 7:77,899,322...77,931,029
JBrowse link
G Wnt1 Wnt family member 1 involved_in ISO (MGI:2679774|PMID:14557550), (MGI:3045659|PMID:15121182) RGD PMID:14557550 PMID:15121182 MGI:2679774 MGI:3045659 NCBI chr 7:140,464,999...140,469,046
Ensembl chr 7:140,464,999...140,469,046
JBrowse link
G Wnt2 Wnt family member 2 involved_in ISO (PMID:20018874)
(MGI:4461115|PMID:20018874)
RGD PMID:20018874 MGI:4461115 NCBI chr 4:45,286,845...45,332,899
Ensembl chr 4:45,292,437...45,332,420
JBrowse link
G Wnt3a Wnt family member 3A involved_in ISO (MGI:2679774|PMID:14557550) RGD PMID:14557550 MGI:2679774 NCBI chr10:45,598,898...45,643,151
Ensembl chr10:45,598,912...45,638,035
JBrowse link
inferior colliculus development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxb1 forkhead box B1 involved_in ISS
ISO
GO_REF:0000024
(MGI:1931655|PMID:11170346)
UniProt
RGD
PMID:11170346 GO_REF:0000024 MGI:1931655 NCBI chr 8:75,992,751...75,995,371
Ensembl chr 8:75,992,755...75,995,371
JBrowse link
G Tfap2d transcription factor AP-2 delta acts_upstream_of_or_within ISO MGI:5296818 (MGI:5295521|PMID:21858141) RGD PMID:21858141 MGI:5295521 NCBI chr 9:25,304,876...25,365,151
Ensembl chr 9:25,304,876...25,365,151
JBrowse link
midbrain dopaminergic neuron differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctnnb1 catenin beta 1 involved_in IEA
ISO
GO_REF:0000107
(MGI:3836885|PMID:19122665)
Ensembl
RGD
PMID:19122665 GO_REF:0000107 MGI:3836885 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Lmx1a LIM homeobox transcription factor 1 alpha involved_in ISO (MGI:5705221|PMID:19951692) RGD PMID:19951692 MGI:5705221 NCBI chr13:85,916,753...86,061,534
Ensembl chr13:85,918,252...86,061,176
JBrowse link
G Rac1 Rac family small GTPase 1 involved_in ISO (MGI:3829860|PMID:18953410), (MGI:5466648|PMID:23109420) RGD PMID:18953410 PMID:23109420 MGI:3829860 MGI:5466648 NCBI chr12:13,090,316...13,111,841
Ensembl chr12:13,090,172...13,111,873
JBrowse link
G Ryk receptor-like tyrosine kinase involved_in ISO (MGI:5707582|PMID:23517308) RGD PMID:23517308 MGI:5707582 NCBI chr 8:111,326,339...111,398,640
Ensembl chr 8:111,326,433...111,397,867
JBrowse link
G Wnt1 Wnt family member 1 involved_in ISO (MGI:5469218|PMID:23324743) RGD PMID:23324743 MGI:5469218 NCBI chr 7:140,464,999...140,469,046
Ensembl chr 7:140,464,999...140,469,046
JBrowse link
G Wnt2 Wnt family member 2 involved_in ISO (PMID:20018874) RGD PMID:20018874 NCBI chr 4:45,286,845...45,332,899
Ensembl chr 4:45,292,437...45,332,420
JBrowse link
G Wnt5a Wnt family member 5A involved_in ISO UniProtKB:P04426 (MGI:2679774|PMID:14557550), (MGI:3829860|PMID:18953410), (MGI:5469218|PMID:23324743), (MGI:5700308|PMID:15748172) RGD PMID:14557550 PMID:15748172 PMID:18953410 PMID:23324743 MGI:2679774 MGI:3829860 MGI:5469218 MGI:5700308 NCBI chr16:4,469,451...4,490,271
Ensembl chr16:4,469,468...4,489,860
JBrowse link
G Wnt9b Wnt family member 9B involved_in ISO (PMID:25640183) RGD PMID:25640183 NCBI chr10:91,785,892...91,808,061
Ensembl chr10:91,785,893...91,807,937
JBrowse link
midbrain morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sos1 SOS Ras/Rac guanine nucleotide exchange factor 1 acts_upstream_of_or_within ISO MGI:2155441 (MGI:85697|PMID:9030684) RGD PMID:9030684 MGI:85697 NCBI chr 6:3,105,443...3,182,977
Ensembl chr 6:3,104,861...3,182,996
JBrowse link
negative regulation of cell proliferation in midbrain term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt5a Wnt family member 5A involved_in IEA
ISO
GO_REF:0000107
(MGI:3829860|PMID:18953410)
Ensembl
RGD
PMID:18953410 GO_REF:0000107 MGI:3829860 NCBI chr16:4,469,451...4,490,271
Ensembl chr16:4,469,468...4,489,860
JBrowse link
non-canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt9b Wnt family member 9B involved_in ISO (PMID:25640183) RGD PMID:25640183 NCBI chr10:91,785,892...91,808,061
Ensembl chr10:91,785,893...91,807,937
JBrowse link
positive regulation of cell proliferation in midbrain term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pitx3 paired-like homeodomain 3 IDA RGD PMID:18385323 RGD:11535083 NCBI chr 1:265,886,766...265,899,947
Ensembl chr 1:265,887,230...265,899,958
JBrowse link
positive regulation of midbrain dopaminergic neuron differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 involved_in ISO (MGI:4948425|PMID:21347250) RGD PMID:21347250 MGI:4948425 NCBI chr 1:248,952,896...248,956,579
Ensembl chr 1:248,895,738...248,898,607
Ensembl chr 1:248,895,738...248,898,607
JBrowse link
positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Csnk1e casein kinase 1, epsilon involved_in NAS PMID:17244647 ParkinsonsUK-UCL PMID:17244647 RGD:10448953 NCBI chr 7:120,651,976...120,675,559
Ensembl chr 7:120,651,881...120,672,359
JBrowse link
regulation of midbrain dopaminergic neuron differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sfrp1 secreted frizzled-related protein 1 involved_in IEA
ISO
GO_REF:0000107
UniProtKB:P97299 (MGI:5448935|PMID:22290867)
Ensembl
RGD
PMID:22290867 GO_REF:0000107 MGI:5448935 NCBI chr16:73,372,007...73,410,777
Ensembl chr16:73,372,007...73,410,777
JBrowse link
G Sfrp2 secreted frizzled-related protein 2 involved_in ISO UniProtKB:Q8C4U3 (MGI:5448935|PMID:22290867) RGD PMID:22290867 MGI:5448935 NCBI chr 2:182,723,732...182,731,277
Ensembl chr 2:182,723,854...182,731,764
JBrowse link
substantia nigra development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actb actin, beta involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr12:13,715,843...13,718,813
Ensembl chr12:13,715,843...13,718,841
JBrowse link
G Atp5pb ATP synthase peripheral stalk-membrane subunit b involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr 2:208,566,385...208,577,147
Ensembl chr 2:208,566,385...208,577,146
Ensembl chr 2:208,566,385...208,577,146
JBrowse link
G Atp5pf ATP synthase peripheral stalk subunit F6 involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr11:24,286,806...24,294,419
Ensembl chr11:24,286,787...24,294,179
JBrowse link
G Basp1 brain abundant, membrane attached signal protein 1 involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr 2:77,586,424...77,632,626
Ensembl chr 2:77,586,424...77,632,628
JBrowse link
G Calm1 calmodulin 1 involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr 6:124,217,241...124,225,292
Ensembl chr 6:124,217,241...124,225,292
JBrowse link
G Calm2 calmodulin 2 involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr 6:11,067,675...11,080,078
Ensembl chr15:65,506,874...65,507,968
JBrowse link
G Calm3 calmodulin 3 involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr 1:78,844,520...78,851,628
Ensembl chr 1:78,843,080...78,851,719
JBrowse link
G Ccdc14 coiled-coil domain containing 14 involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr11:69,281,000...69,316,897
Ensembl chr11:69,281,554...69,316,848
JBrowse link
G Cdc42 cell division cycle 42 involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr 5:155,690,267...155,728,385
Ensembl chr 5:155,691,390...155,728,300
JBrowse link
G Ckb creatine kinase B involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr 6:136,142,956...136,145,838
Ensembl chr 6:136,142,956...136,145,837
JBrowse link
G Cnp 2',3'-cyclic nucleotide 3' phosphodiesterase involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr10:88,490,798...88,497,357
Ensembl chr10:88,490,798...88,497,356
JBrowse link
G Cox6b1 cytochrome c oxidase subunit 6B1 involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr 1:89,075,987...89,084,834
Ensembl chr 1:89,075,975...89,084,859
Ensembl chr 2:89,075,975...89,084,859
JBrowse link
G Dynll1 dynein light chain LC8-type 1 involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr12:47,074,200...47,076,573
Ensembl chr12:47,074,200...47,076,572
JBrowse link
G Eno3 enolase 3 involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr10:57,278,271...57,283,661
Ensembl chr10:57,278,307...57,283,653
JBrowse link
G Fgf2 fibroblast growth factor 2 acts_upstream_of_or_within ISO MGI:1857458 (MGI:3696489|PMID:17234579) RGD PMID:17234579 MGI:3696489 NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681
JBrowse link
G Fgf9 fibroblast growth factor 9 involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr15:38,341,657...38,386,945
Ensembl chr15:38,341,089...38,387,316
JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 acts_upstream_of_or_within ISO MGI:1931521 (MGI:3696489|PMID:17234579) RGD PMID:17234579 MGI:3696489 NCBI chr14:82,272,322...82,287,739
Ensembl chr14:82,273,070...82,287,706
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
G Glud1 glutamate dehydrogenase 1 involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr16:10,661,486...10,695,557
Ensembl chr16:10,662,021...10,695,557
JBrowse link
G Gnb4 G protein subunit beta 4 involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr 2:118,978,965...119,007,877
Ensembl chr 2:118,978,973...119,007,835
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Ina internexin neuronal intermediate filament protein, alpha involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr 1:266,782,835...266,794,389
Ensembl chr 1:266,781,617...266,794,431
JBrowse link
G Ldha lactate dehydrogenase A involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr 1:102,900,288...102,909,713
Ensembl chr 1:102,900,286...102,909,707
JBrowse link
G Mag myelin-associated glycoprotein involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr 1:89,345,325...89,360,905
Ensembl chr 1:89,345,429...89,360,733
JBrowse link
G Maob monoamine oxidase B involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr  X:6,430,694...6,533,520
Ensembl chr  X:6,430,594...6,533,534
JBrowse link
G Mapkap1 MAPK associated protein 1 involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr 3:13,484,952...13,701,772
Ensembl chr 3:13,484,838...13,701,757
JBrowse link
G Mbp myelin basic protein involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr18:79,326,738...79,437,310
Ensembl chr18:79,326,738...79,437,310
JBrowse link
G Ndrg2 NDRG family member 2 involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr15:28,305,820...28,314,459
Ensembl chr15:28,305,821...28,314,459
JBrowse link
G Ndufs3 NADH:ubiquinone oxidoreductase core subunit S3 involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr 3:79,721,686...79,728,863
Ensembl chr 3:79,721,694...79,728,879
JBrowse link
G Padi2 peptidyl arginine deiminase 2 involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr 5:159,428,479...159,471,113
Ensembl chr 5:159,428,515...159,471,144
JBrowse link
G Plp1 proteolipid protein 1 involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr  X:107,494,326...107,511,355
Ensembl chr  X:107,496,072...107,511,348
JBrowse link
G Rad1 RAD1 checkpoint DNA exonuclease involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr 2:60,461,513...60,469,646
Ensembl chr 2:60,461,551...60,469,685
JBrowse link
G Rhoa ras homolog family member A involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr 8:117,082,440...117,116,244
Ensembl chr 8:117,106,576...117,116,167
JBrowse link
G S100a1 S100 calcium binding protein A1 involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr 2:189,900,505...189,905,348
Ensembl chr 2:189,900,667...189,903,219
JBrowse link
G Sec16a SEC16 homolog A, endoplasmic reticulum export factor involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr 3:3,856,218...3,890,785
Ensembl chr 3:3,856,218...3,890,758
JBrowse link
G Sirt2 sirtuin 2 involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr 1:86,948,866...86,971,954
Ensembl chr 1:86,948,918...86,971,952
JBrowse link
G Suds3 SDS3 homolog, SIN3A corepressor complex component involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr12:45,199,012...45,221,507
Ensembl chr12:45,199,577...45,221,512
JBrowse link
G Syngr3 synaptogyrin 3 involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr10:14,051,413...14,056,169
Ensembl chr10:14,051,415...14,056,169
JBrowse link
G Sypl2 synaptophysin-like 2 involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr 2:211,003,046...211,017,778
Ensembl chr 2:211,003,046...211,017,778
JBrowse link
G Ttbk1 tau tubulin kinase 1 involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr 9:16,862,305...16,899,399
Ensembl chr 9:16,862,248...16,902,199
JBrowse link
G Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr10:63,884,338...63,921,709
Ensembl chr10:63,884,338...63,921,709
JBrowse link
G Ywhah tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr14:83,053,041...83,062,424
Ensembl chr14:83,053,041...83,062,424
JBrowse link
G Ywhaq tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr 6:43,463,294...43,493,816
Ensembl chr 6:43,463,294...43,493,816
JBrowse link
G Zfp148 zinc finger protein 148 involved_in ISO (PMID:22926577) UniProt PMID:22926577 NCBI chr11:70,509,909...70,618,422
Ensembl chr11:70,514,750...70,618,347
JBrowse link
Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt5a Wnt family member 5A involved_in IEA
ISO
GO_REF:0000107
(MGI:5707582|PMID:23517308)
Ensembl
RGD
PMID:23517308 GO_REF:0000107 MGI:5707582 NCBI chr16:4,469,451...4,490,271
Ensembl chr16:4,469,468...4,489,860
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19612
    developmental process 6792
      anatomical structure development 6265
        midbrain development 97
          cell proliferation in midbrain + 7
          corpora quadrigemina development + 2
          midbrain dopaminergic neuron differentiation + 13
          midbrain morphogenesis 1
          substantia nigra development 44
          ventral tegmental area development 0
Path 2
Term Annotations click to browse term
  biological_process 19612
    developmental process 6792
      anatomical structure development 6265
        multicellular organism development 5747
          system development 5290
            nervous system development 2718
              central nervous system development 1266
                brain development 972
                  midbrain development 97
                    cell proliferation in midbrain + 7
                    corpora quadrigemina development + 2
                    midbrain dopaminergic neuron differentiation + 13
                    midbrain morphogenesis 1
                    substantia nigra development 44
                    ventral tegmental area development 0
paths to the root