Wnt2 (Wnt family member 2) - Rat Genome Database

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Gene: Wnt2 (Wnt family member 2) Heterocephalus glaber
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Symbol: Wnt2
Name: Wnt family member 2
RGD ID: 18929442
Description: ENCODES a protein that exhibits receptor ligand activity (ortholog); INVOLVED IN atrial cardiac muscle tissue morphogenesis (ortholog); canonical Wnt signaling pathway (ortholog); cardiac epithelial to mesenchymal transition (ortholog); PARTICIPATES IN Wnt signaling pathway; Wnt signaling pathway; Wnt signaling, canonical pathway; ASSOCIATED WITH autistic disorder (ortholog); breast cancer (ortholog); breast carcinoma (ortholog); FOUND IN collagen-containing extracellular matrix (ortholog); cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Protein Wnt-2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248272,045,595 - 2,089,442 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248272,045,733 - 2,088,284 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Wnt2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248272,045,595 - 2,089,442 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248272,045,733 - 2,088,284 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
WNT2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387117,275,451 - 117,323,058 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7117,275,451 - 117,323,152 (-)EnsemblGRCh38hg38GRCh38
GRCh377116,915,505 - 116,963,112 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367116,704,518 - 116,750,579 (-)NCBINCBI36Build 36hg18NCBI36
Build 347116,511,232 - 116,557,294NCBI
Celera7111,724,862 - 111,771,525 (-)NCBICelera
Cytogenetic Map7q31.2NCBI
HuRef7111,282,485 - 111,328,966 (-)NCBIHuRef
CHM1_17116,850,055 - 116,896,705 (-)NCBICHM1_1
T2T-CHM13v2.07118,590,786 - 118,638,396 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27116,312,120 - 116,358,781 (-)NCBI
Wnt2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39617,988,939 - 18,032,771 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl617,988,939 - 18,030,584 (-)EnsemblGRCm39 Ensembl
GRCm38617,985,474 - 18,032,772 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl617,988,940 - 18,030,585 (-)EnsemblGRCm38mm10GRCm38
MGSCv37617,938,940 - 17,980,445 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36617,938,940 - 17,980,356 (-)NCBIMGSCv36mm8
Celera618,070,129 - 18,111,436 (-)NCBICelera
Cytogenetic Map6A2NCBI
cM Map68.08NCBI
Wnt2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8447,294,300 - 47,340,284 (-)NCBIGRCr8
mRatBN7.2446,328,408 - 46,374,673 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl446,333,998 - 46,374,402 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0445,286,845 - 45,332,899 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl445,292,437 - 45,332,420 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0445,892,395 - 45,936,605 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4443,649,783 - 43,689,596 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1443,857,074 - 43,859,488 (-)NCBI
Celera441,596,263 - 41,642,309 (-)NCBICelera
Cytogenetic Map4q22NCBI
Wnt2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543222,984,170 - 23,027,705 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543222,988,208 - 23,024,530 (-)NCBIChiLan1.0ChiLan1.0
WNT2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26154,101,025 - 154,151,405 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan176,111,284 - 6,161,665 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07109,244,772 - 109,291,472 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17121,939,254 - 121,985,862 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7121,936,031 - 121,985,862 (-)Ensemblpanpan1.1panPan2
WNT2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11456,123,735 - 56,172,113 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1456,129,248 - 56,172,069 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1455,519,061 - 55,567,484 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01456,163,101 - 56,211,441 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1456,166,256 - 56,213,190 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11456,195,055 - 56,243,473 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01455,884,128 - 55,931,047 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01456,253,933 - 56,302,214 (-)NCBIUU_Cfam_GSD_1.0
Wnt2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511844,819,573 - 44,865,128 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365891,825,209 - 1,866,889 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365891,825,209 - 1,866,898 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
WNT2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1828,946,326 - 28,993,961 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11828,945,825 - 28,993,969 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21830,790,071 - 30,838,269 (-)NCBISscrofa10.2Sscrofa10.2susScr3
WNT2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12185,955,517 - 86,005,664 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2185,955,145 - 86,001,730 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604217,730,443 - 17,777,632 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000003119   ⟹   ENSHGLP00000003064
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248272,045,595 - 2,089,442 (+)Ensembl
RefSeq Acc Id: XM_004865257   ⟹   XP_004865314
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248272,045,733 - 2,088,284 (+)NCBI
RefSeq Acc Id: XM_021244770   ⟹   XP_021100429
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248272,045,733 - 2,088,284 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004865314 (Get FASTA)   NCBI Sequence Viewer  
  XP_021100429 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB03922 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000003064
  ENSHGLP00100005253
RefSeq Acc Id: XP_004865314   ⟸   XM_004865257
- Peptide Label: isoform X1
- UniProtKB: G5B3R0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021100429   ⟸   XM_021244770
- Peptide Label: isoform X2
Ensembl Acc Id: ENSHGLP00000003064   ⟸   ENSHGLT00000003119


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000002291 Ensembl, ENTREZGENE
  ENSHGLG00100003985 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000003119 ENTREZGENE
  ENSHGLT00100005334 UniProtKB/TrEMBL
Gene3D-CATH 3.30.2460.20 UniProtKB/TrEMBL
InterPro Wnt UniProtKB/TrEMBL
  Wnt2 UniProtKB/TrEMBL
  Wnt_C UniProtKB/TrEMBL
  Wnt_CS UniProtKB/TrEMBL
KEGG Report hgl:101723565 UniProtKB/TrEMBL
NCBI Gene Wnt2 ENTREZGENE
PANTHER PROTEIN WNT-2 UniProtKB/TrEMBL
  PTHR12027 UniProtKB/TrEMBL
Pfam wnt UniProtKB/TrEMBL
PRINTS WNT2PROTEIN UniProtKB/TrEMBL
  WNTPROTEIN UniProtKB/TrEMBL
PROSITE WNT1 UniProtKB/TrEMBL
SMART WNT1 UniProtKB/TrEMBL
UniProt G5B3R0 ENTREZGENE, UniProtKB/TrEMBL