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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of type II interferon production
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Accession:GO:0032729 term browser browse the term
Definition:Any process that activates or increases the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon.
Synonyms:exact_synonym: positive regulation of interferon-gamma production;   up regulation of interferon-gamma production;   upregulation of interferon-gamma production
 narrow_synonym: activation of interferon-gamma production;   positive regulation of interferon-gamma biosynthetic process;   positive regulation of interferon-gamma secretion;   stimulation of interferon-gamma production
 alt_id: GO:0045078;   GO:1902715
 only_in_taxon: NCBITaxon:6072 ! Eumetazoa


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positive regulation of type II interferon production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18025176) Ensembl
MGI		 PMID:18025176 GO_REF:0000107 NCBI chr 9:53,118,462...53,262,092
Ensembl chr 9:53,119,641...53,261,307 		JBrowse link
G ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase acts_upstream_of_or_within ISO (PMID:18025176) MGI PMID:18025176 NCBI chr 7:20,696,659...20,735,362
Ensembl chr 7:20,700,144...20,727,410 		JBrowse link
G APP amyloid beta precursor protein involved_in ISO (PMID:17255335) ARUK-UCL PMID:17255335 NCBI chr31:21,351,207...21,614,466
Ensembl chr31:21,351,207...21,614,337 		JBrowse link
G ARID5A AT-rich interaction domain 5A involved_in ISO (MGI:5780752|PMID:27022145), (MGI:5887181|PMID:27671645) UniProt PMID:27022145 PMID:27671645 MGI:5780752 MGI:5887181 NCBI chr17:34,320,791...34,333,660
Ensembl chr17:34,321,177...34,333,621 		JBrowse link
G BCL3 BCL3 transcription coactivator involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16790793) Ensembl
MGI		 PMID:16790793 GO_REF:0000107 NCBI chr 1:110,620,850...110,628,830
Ensembl chr 1:110,620,827...110,654,771 		JBrowse link
G CARMIL2 capping protein regulator and myosin 1 linker 2 acts_upstream_of_or_within ISO (PMID:23793062) MGI PMID:23793062 NCBI chr 5:81,792,683...81,804,274
Ensembl chr 5:81,792,155...81,804,152 		JBrowse link
G CCR2 C-C motif chemokine receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:42,305,344...42,313,258
Ensembl chr20:42,307,580...42,308,698 		JBrowse link
G CD14 CD14 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:35,790,505...35,792,967 JBrowse link
G CD160 CD160 molecule involved_in ISO (MGI:5644003|PMID:25711213) UniProt PMID:25711213 MGI:5644003 NCBI chr17:58,548,137...58,564,077
Ensembl chr17:58,555,851...58,563,341 		JBrowse link
G CD1D CD1d molecule acts_upstream_of_or_within ISO (PMID:9133426) MGI PMID:9133426 NCBI chr38:23,489,169...23,491,712 JBrowse link
G CD2 CD2 molecule involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr17:54,171,764...54,184,221
Ensembl chr17:54,171,848...54,184,225 		JBrowse link
G CD226 CD226 molecule involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24658051) TreeGrafter
MGI		 PMID:24658051 GO_REF:0000118 NCBI chr 1:8,348,628...8,437,520
Ensembl chr 1:8,351,207...8,435,145 		JBrowse link
G CD244 CD244 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr38:21,495,649...21,522,656
Ensembl chr38:21,495,720...21,517,043 		JBrowse link
G CD276 CD276 molecule involved_in ISO (PMID:11224528) HGNC-UCL PMID:11224528 NCBI chr30:36,975,085...36,990,012
Ensembl chr30:36,975,085...36,988,924 		JBrowse link
G CD3E CD3 epsilon subunit of T-cell receptor complex acts_upstream_of_or_within ISO (PMID:11894097) MGI PMID:11894097 NCBI chr 5:15,403,724...15,415,259
Ensembl chr 5:15,403,710...15,415,260 		JBrowse link
G CD40LG CD40 ligand ISO RGD PMID:18262271 RGD:2313421 NCBI chr  X:107,001,421...107,023,007
Ensembl chr  X:107,010,890...107,023,006 		JBrowse link
G CEBPG CCAAT enhancer binding protein gamma involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:118,777,110...118,784,397
Ensembl chr 1:118,778,224...118,778,667 		JBrowse link
G CLEC7A C-type lectin domain containing 7A involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:35,852,685...35,885,673
Ensembl chr27:35,853,099...36,007,157 		JBrowse link
G CLEC7A C-type lectin domain containing 7A involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:35,896,421...35,920,649
Ensembl chr27:35,853,099...36,007,157 		JBrowse link
G CRTAM cytotoxic and regulatory T cell molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:11,458,360...11,485,469
Ensembl chr 5:11,458,008...11,485,448 		JBrowse link
G CYRIB CYFIP related Rac1 interactor B involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:26,942,036...27,056,547
Ensembl chr13:26,942,229...27,003,644 		JBrowse link
G F2RL1 F2R like trypsin receptor 1 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:29,801,119...29,810,006
Ensembl chr 3:29,800,211...29,810,180 		JBrowse link
G FADD Fas associated via death domain involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:48,087,447...48,094,497 JBrowse link
G FLT3 fms related receptor tyrosine kinase 3 acts_upstream_of_or_within ISO (PMID:20457904) MGI PMID:20457904 NCBI chr25:11,551,372...11,670,891
Ensembl chr25:11,581,206...11,692,284 		JBrowse link
G FZD5 frizzled class receptor 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr37:16,123,788...16,126,634
Ensembl chr37:16,123,798...16,125,567 		JBrowse link
G HAVCR2 hepatitis A virus cellular receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:53,018,990...53,032,035
Ensembl chr 4:53,012,234...53,033,393 		JBrowse link
G HRAS HRas proto-oncogene, GTPase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21444916) Ensembl
MGI		 PMID:21444916 GO_REF:0000107 NCBI chr18:25,642,844...25,644,717
Ensembl chr18:25,642,844...25,644,717 		JBrowse link
G HSPD1 heat shock protein family D (Hsp60) member 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:17164250)
(PMID:15371451), (PMID:17164250)		 MGI
TreeGrafter		 PMID:15371451 PMID:17164250 GO_REF:0000118 NCBI chr37:7,010,421...7,025,912 JBrowse link
G IFNAR1 interferon alpha and beta receptor subunit 1 acts_upstream_of_or_within ISO (PMID:17164250) MGI PMID:17164250 NCBI chr31:28,854,765...28,876,399 JBrowse link
G IL12A interleukin 12A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15843532)
(PMID:9348310)
(PMID:21444916)		 Ensembl
MGI		 PMID:9348310 PMID:15843532 PMID:21444916 GO_REF:0000107 NCBI chr34:26,125,529...26,133,546
Ensembl chr34:26,124,770...26,133,550 		JBrowse link
G IL12B interleukin 12B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9348310)
(PMID:21444916)
(PMID:15843532)
(PMID:16949315)		 Ensembl
MGI		 PMID:9348310 PMID:15843532 PMID:16949315 PMID:21444916 GO_REF:0000107 NCBI chr 4:51,178,637...51,194,606
Ensembl chr 4:51,183,568...51,193,228 		JBrowse link
G IL12RB1 interleukin 12 receptor subunit beta 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:44,885,410...44,908,139
Ensembl chr20:44,885,337...44,904,538 		JBrowse link
G IL12RB2 interleukin 12 receptor subunit beta 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:43,197,034...43,269,571
Ensembl chr 5:43,197,034...43,257,594 		JBrowse link
G IL18 interleukin 18 involved_in
acts_upstream_of_or_within		 IDA
ISS
IEA
ISO		 (PMID:10048765)
(PMID:10227969), (PMID:11894097), (PMID:11894098), (PMID:15843532)
(PMID:15843532)		 UniProt
Ensembl
MGI		 PMID:10048765 PMID:10227969 PMID:11894097 PMID:11894098 PMID:15843532 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:20,972,742...20,995,327
Ensembl chr 5:20,972,871...20,995,348 		JBrowse link
G IL18R1 interleukin 18 receptor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10227969) Ensembl
TreeGrafter
MGI		 PMID:10227969 GO_REF:0000107 GO_REF:0000118 NCBI chr10:40,614,336...40,653,300
Ensembl chr10:40,615,312...40,653,454 		JBrowse link
G IL1B interleukin 1 beta involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr17:37,019,329...37,033,388
Ensembl chr17:37,019,329...37,024,458 		JBrowse link
G IL1R1 interleukin 1 receptor type 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:40,825,986...40,897,898
Ensembl chr10:40,827,377...40,897,596 		JBrowse link
G IL2 interleukin 2 acts_upstream_of_or_within ISO (PMID:17213291) MGI PMID:17213291 NCBI chr19:17,750,780...17,756,394
Ensembl chr19:17,750,780...17,756,394 		JBrowse link
G IL21 interleukin 21 acts_upstream_of_or_within ISO (PMID:14764669) MGI PMID:14764669 NCBI chr19:17,641,833...17,651,275
Ensembl chr19:17,641,833...17,651,266 		JBrowse link
G IL23A interleukin 23 subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:635,384...640,715
Ensembl chr10:638,719...640,359 		JBrowse link
G IL23R interleukin 23 receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:43,307,422...43,369,806
Ensembl chr 5:43,308,982...43,368,474 		JBrowse link
G IL27 interleukin 27 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:18,243,988...18,248,369
Ensembl chr 6:18,244,040...18,247,635 		JBrowse link
G IL27RA interleukin 27 receptor subunit alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11057672) Ensembl
MGI		 PMID:11057672 GO_REF:0000107 NCBI chr20:48,456,766...48,475,414
Ensembl chr20:48,457,134...48,472,450 		JBrowse link
G IL29L interleukin 29-like involved_in ISO (PMID:19346497) UniProt PMID:19346497 NCBI chr24:36,440,445...36,441,017
Ensembl chr24:36,440,445...36,441,017 		JBrowse link
G IRF8 interferon regulatory factor 8 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9348310) Ensembl
MGI		 PMID:9348310 GO_REF:0000107 NCBI chr 5:66,789,264...66,812,477
Ensembl chr 5:66,791,350...66,842,179 		JBrowse link
G ISG15 ISG15 ubiquitin like modifier involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:56,230,879...56,237,354
Ensembl chr 5:56,236,318...56,404,695 		JBrowse link
G ISL1 ISL LIM homeobox 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:63,638,009...63,648,492
Ensembl chr 4:63,637,443...63,648,183 		JBrowse link
G JAK2 Janus kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:93,321,055...93,438,898
Ensembl chr 1:93,142,635...93,435,997 		JBrowse link
G KLRK1 killer cell lectin like receptor K1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12645935) Ensembl
MGI		 PMID:12645935 GO_REF:0000107 NCBI chr27:35,634,938...35,658,978
Ensembl chr27:35,639,280...35,658,882 		JBrowse link
G KRAS KRAS proto-oncogene, GTPase involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:22,261,753...22,296,704
Ensembl chr27:22,257,941...22,293,369 		JBrowse link
G LGALS9 galectin 9 involved_in ISO (PMID:20209097) UniProt PMID:20209097 NCBI chr 9:42,154,613...42,170,423
Ensembl chr 9:42,154,702...42,170,391 		JBrowse link
G LTA lymphotoxin alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9834074) Ensembl
MGI		 PMID:9834074 GO_REF:0000107 NCBI chr12:1,070,608...1,073,053
Ensembl chr12:1,071,192...1,073,067 		JBrowse link
G MIR155 microRNA mir-155 acts_upstream_of_or_within ISO (PMID:22517757) MGI PMID:22517757 NCBI chr31:21,078,768...21,078,828
Ensembl chr31:21,078,758...21,078,833 		JBrowse link
G MIR21 microRNA mir-21 acts_upstream_of_or_within ISO (PMID:22517757) MGI PMID:22517757 NCBI chr 9:34,340,550...34,340,609
Ensembl chr 9:34,340,533...34,340,624 		JBrowse link
G NRAS NRAS proto-oncogene, GTPase acts_upstream_of_or_within ISO (PMID:21444916) MGI PMID:21444916 NCBI chr17:52,411,733...52,418,788
Ensembl chr17:52,411,733...52,418,788 		JBrowse link
G PDE4B phosphodiesterase 4B involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:44,063,145...44,606,070
Ensembl chr 5:44,065,106...44,500,999 		JBrowse link
G PDE4D phosphodiesterase 4D involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:45,843,767...47,245,263
Ensembl chr 2:45,846,294...46,949,912 		JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 involved_in ISO (PMID:23991106) UniProt PMID:23991106 NCBI chr17:51,623,628...51,683,039
Ensembl chr17:51,623,623...51,682,858 		JBrowse link
G PYCARD PYD and CARD domain containing involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:17,049,352...17,051,348
Ensembl chr 6:17,049,705...17,051,240 		JBrowse link
G RASGRP1 RAS guanyl releasing protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr30:5,840,901...5,914,804
Ensembl chr30:5,841,738...5,914,810 		JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11894098)
(PMID:11894097)		 Ensembl
MGI		 PMID:11894097 PMID:11894098 GO_REF:0000107 NCBI chr29:35,283,209...35,311,608
Ensembl chr29:35,282,072...35,311,333 		JBrowse link
G RUNX1 RUNX family transcription factor 1 involved_in ISO (MGI:3710039|PMID:17377532) UniProt PMID:17377532 MGI:3710039 NCBI chr31:30,170,859...30,420,344
Ensembl chr31:30,170,605...30,420,839 		JBrowse link
G SASH3 SAM and SH3 domain containing 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16227612) Ensembl
MGI		 PMID:16227612 GO_REF:0000107 NCBI chr  X:100,989,605...101,003,162
Ensembl chr  X:100,989,685...101,001,885 		JBrowse link
G SCRIB scribble planar cell polarity protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:37,356,405...37,374,765
Ensembl chr13:37,356,405...37,374,681 		JBrowse link
G SLAMF1 signaling lymphocytic activation molecule family member 1 involved_in IEA
IBA		 Ensembl
TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr38:21,653,801...21,685,408
Ensembl chr38:21,653,487...21,685,408 		JBrowse link
G SLAMF6 SLAM family member 6 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr38:21,742,228...21,769,521
Ensembl chr38:21,742,301...21,764,494 		JBrowse link
G SLC11A1 solute carrier family 11 member 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18984740) Ensembl
MGI		 PMID:18984740 GO_REF:0000107 NCBI chr37:25,039,203...25,047,461
Ensembl chr37:25,038,360...25,047,282 		JBrowse link
G SLC7A5 solute carrier family 7 member 5 acts_upstream_of
involved_in		 ISO
IEA		 (PMID:24038088) ARUK-UCL
Ensembl		 PMID:24038088 GO_REF:0000107 NCBI chr 5:65,313,105...65,343,858
Ensembl chr 5:65,313,105...65,343,858 		JBrowse link
G TICAM2 toll like receptor adaptor molecule 2 involved_in ISO (MGI:5488868|PMID:22685567) UniProt PMID:22685567 MGI:5488868 NCBI chr11:5,312,383...5,313,099
Ensembl chr11:5,312,383...5,313,099 		JBrowse link
G TLR3 toll like receptor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:44,617,012...44,633,591
Ensembl chr16:44,550,846...44,653,247 		JBrowse link
G TLR4 toll like receptor 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:71,356,390...71,367,166
Ensembl chr11:71,356,390...71,367,165 		JBrowse link
G TLR7 toll like receptor 7 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:9,331,243...9,360,461
Ensembl chr  X:9,314,815...9,359,603 		JBrowse link
G TLR8 toll like receptor 8 involved_in ISO (PMID:16286015) UniProt PMID:16286015 NCBI chr  X:9,381,159...9,399,938 JBrowse link
G TLR9 toll like receptor 9 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr20:37,529,322...37,547,117
Ensembl chr20:37,542,340...37,547,114
Ensembl chr20:37,542,340...37,547,114 		JBrowse link
G TNF tumor necrosis factor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9834074) Ensembl
MGI		 PMID:9834074 GO_REF:0000107 NCBI chr12:1,074,561...1,076,425
Ensembl chr12:1,074,552...1,076,425 		JBrowse link
G TNFRSF13C TNF receptor superfamily member 13C acts_upstream_of_or_within ISO (PMID:15368291) MGI PMID:15368291 NCBI chr10:23,430,960...23,434,972
Ensembl chr10:23,433,052...23,438,946 		JBrowse link
G TNFSF4 TNF superfamily member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:25,883,297...25,909,608
Ensembl chr 7:25,883,251...25,906,892 		JBrowse link
G TNFSF9 TNF superfamily member 9 ISO RGD PMID:19187795 RGD:2317344 NCBI chr20:53,680,882...53,682,521
Ensembl chr20:53,679,880...53,682,706 		JBrowse link
G TRIM27 tripartite motif containing 27 involved_in IEA Ensembl GO_REF:0000107 NCBI chr35:25,904,381...25,922,531
Ensembl chr35:25,905,396...25,923,336 		JBrowse link
G TXK TXK tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:43,911,881...43,977,499
Ensembl chr13:43,914,534...43,976,655 		JBrowse link
G TYK2 tyrosine kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:50,747,145...50,770,008
Ensembl chr20:50,748,329...50,769,216 		JBrowse link
G WNT5A Wnt family member 5A involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:34,756,430...34,790,937
Ensembl chr20:34,769,930...34,786,673 		JBrowse link
G ZFPM1 zinc finger protein, FOG family member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:64,812,353...64,863,278 JBrowse link
G ZP3 zona pellucida glycoprotein 3 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:7,586,212...7,594,610
Ensembl chr 6:7,585,970...7,594,610 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17919
    multicellular organismal process 8092
      positive regulation of multicellular organismal process 1869
        positive regulation of cytokine production 541
          positive regulation of type II interferon production 84
Path 2
Term Annotations click to browse term
  biological_process 17919
    biological regulation 12448
      regulation of biological process 12084
        regulation of metabolic process 6413
          regulation of biosynthetic process 5262
            regulation of cellular biosynthetic process 5176
              regulation of macromolecule biosynthetic process 5080
                regulation of gene expression 4963
                  regulation of cytokine production 891
                    positive regulation of cytokine production 541
                      positive regulation of type II interferon production 84
paths to the root