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Gene: APP (amyloid beta precursor protein) Canis lupus familiaris
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Symbol: APP
Name: amyloid beta precursor protein
Description: ENCODES a protein that exhibits enzyme binding (inferred); heparin binding (inferred); identical protein binding (inferred); INVOLVED IN cognition (ortholog); PARTICIPATES IN Alzheimer's disease pathway; glypican signaling pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); Alzheimer's disease 1 (ortholog); Alzheimer's Disease, Early-Onset, with Cerebral Amyloid Angiopathy (ortholog); FOUND IN early endosome (ortholog); Golgi-associated vesicle (ortholog); recycling endosome (ortholog); INTERACTS WITH copper atom; copper(0)
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: ABPP; alzheimer disease amyloid A4 protein homolog; amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease); amyloid beta A4 protein; amyloid precursor protein; beta-amyloid precursor protein
Orthologs:
Homo sapiens (human) : APP (amyloid beta precursor protein)  HGNC  Alliance
Mus musculus (house mouse) : App (amyloid beta (A4) precursor protein)  MGI  Alliance
Rattus norvegicus (Norway rat) : App (amyloid beta precursor protein)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : App (amyloid beta precursor protein)
Pan paniscus (bonobo/pygmy chimpanzee) : APP (amyloid beta precursor protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : App (amyloid beta precursor protein)
Sus scrofa (pig) : APP (amyloid beta precursor protein)
Chlorocebus sabaeus (African green monkey) : APP (amyloid beta precursor protein)
Heterocephalus glaber (naked mole-rat) : App (amyloid beta precursor protein)
more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl3121,351,207 - 21,614,337 (-)Ensembl
CanFam3.13121,351,207 - 21,614,466 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - uncurated

Genomics

Comparative Map Data

Expression


Sequence

Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
 
More on APP
NCBI Gene
Ensembl Gene
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 12199021
Created: 2017-01-24
Species: Canis lupus familiaris
Last Modified: 2019-12-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.