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ONTOLOGY REPORT - ANNOTATIONS

Term:response to lead ion
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Accession:GO:0010288 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lead ion stimulus.


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response to lead ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALAD aminolevulinate dehydratase involved_in ISO
IEA		 RGD
Ensembl		 PMID:16597373 GO_REF:0000107 RGD:1599014 NCBI chr 9:113,386,312...113,401,284
Ensembl chr 9:113,386,312...113,401,290 		JBrowse link
G ALAS2 5'-aminolevulinate synthase 2 ISO RGD PMID:16597373 RGD:1599014 NCBI chr  X:55,009,055...55,030,977
Ensembl chr  X:55,009,055...55,030,977 		JBrowse link
G APP amyloid beta precursor protein ISO RGD PMID:16230335 PMID:29908845 RGD:10054254 RGD:13782138 NCBI chr21:25,880,550...26,171,128
Ensembl chr21:25,880,535...26,171,128 		JBrowse link
G ATP7A ATPase copper transporting alpha involved_in ISO
IEA		 RGD
Ensembl		 PMID:25579025 GO_REF:0000107 RGD:11341668 NCBI chr  X:77,910,693...78,050,395
Ensembl chr  X:77,910,690...78,050,395 		JBrowse link
G BACE1 beta-secretase 1 involved_in ISO
IEA		 RGD
Ensembl		 PMID:29908845 GO_REF:0000107 RGD:13782138 NCBI chr11:117,285,698...117,316,256
Ensembl chr11:117,285,232...117,316,259 		JBrowse link
G BCL2L1 BCL2 like 1 ISO RGD PMID:17912701 RGD:1643487 NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989 		JBrowse link
G BECN1 beclin 1 involved_in ISO
IEA		 RGD
Ensembl		 PMID:22927075 GO_REF:0000107 RGD:11561915 NCBI chr17:42,810,132...42,824,282
Ensembl chr17:42,810,134...42,833,350 		JBrowse link
G CAT catalase involved_in ISO
IEA		 RGD
Ensembl		 PMID:15721881 GO_REF:0000107 RGD:9068900 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CPOX coproporphyrinogen oxidase ISO RGD PMID:656697 RGD:4145135 NCBI chr 3:98,570,488...98,593,611
Ensembl chr 3:98,579,446...98,593,648 		JBrowse link
G CRP C-reactive protein ISO RGD PMID:21378372 RGD:5131295 NCBI chr 1:159,712,289...159,714,589
Ensembl chr 1:159,712,289...159,714,589 		JBrowse link
G CRYAA crystallin alpha A ISO RGD PMID:15905016 RGD:1600983 NCBI chr21:43,169,008...43,172,810
Ensembl chr21:43,169,008...43,172,805 		JBrowse link
G CYP51A1 cytochrome P450 family 51 subfamily A member 1 ISO RGD PMID:12111004 RGD:41412167 NCBI chr 7:92,112,153...92,134,803
Ensembl chr 7:92,084,987...92,134,803 		JBrowse link
G DNMT1 DNA methyltransferase 1 ISO RGD PMID:23246732 RGD:9588316 NCBI chr19:10,133,346...10,194,953
Ensembl chr19:10,133,342...10,231,286 		JBrowse link
G DNMT3A DNA methyltransferase 3 alpha involved_in ISO
IEA		 RGD
Ensembl		 PMID:23246732 GO_REF:0000107 RGD:9588316 NCBI chr 2:25,227,874...25,342,590
Ensembl chr 2:25,227,855...25,342,590 		JBrowse link
G FECH ferrochelatase involved_in ISO
IEA		 RGD
Ensembl		 PMID:4065316 GO_REF:0000107 RGD:4144206 NCBI chr18:57,544,377...57,586,702
Ensembl chr18:57,544,377...57,586,732 		JBrowse link
G FTL ferritin light chain ISO RGD PMID:19332663 RGD:5509838 NCBI chr19:48,965,309...48,966,879
Ensembl chr19:48,965,309...48,966,879 		JBrowse link
G GSTM1 glutathione S-transferase mu 1 ISO RGD PMID:9750042 RGD:7495837 NCBI chr 1:109,687,817...109,693,745
Ensembl chr 1:109,687,814...109,709,039 		JBrowse link
G HMBS hydroxymethylbilane synthase ISO RGD PMID:16566714 RGD:4144781 NCBI chr11:119,084,881...119,093,549
Ensembl chr11:119,084,866...119,093,834 		JBrowse link
G HP haptoglobin ISO RGD PMID:9082656 RGD:1626395 NCBI chr16:72,054,505...72,061,055
Ensembl chr16:72,054,505...72,061,055 		JBrowse link
G HSD17B3 hydroxysteroid 17-beta dehydrogenase 3 ISO RGD PMID:19652923 RGD:4890953 NCBI chr 9:96,235,306...96,302,176
Ensembl chr 9:96,235,306...96,302,176 		JBrowse link
G HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 ISO RGD PMID:18972398 RGD:4890965 NCBI chr 1:119,507,203...119,515,058
Ensembl chr 1:119,507,198...119,515,054 		JBrowse link
G HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 ISO RGD PMID:18972398 RGD:4890965 NCBI chr 1:119,414,931...119,423,034
Ensembl chr 1:119,414,931...119,423,035 		JBrowse link
G LCT lactase ISO RGD PMID:16092086 RGD:1600247 NCBI chr 2:135,787,850...135,837,184
Ensembl chr 2:135,787,850...135,837,184 		JBrowse link
G MAP1LC3A microtubule associated protein 1 light chain 3 alpha involved_in ISO
IEA		 RGD
Ensembl		 PMID:22927075 GO_REF:0000107 RGD:11561915 NCBI chr20:34,546,844...34,560,345
Ensembl chr20:34,546,854...34,560,345 		JBrowse link
G MAPT microtubule associated protein tau involved_in ISS ARUK-UCL GO_REF:0000024 NCBI chr17:45,894,554...46,028,334
Ensembl chr17:45,894,527...46,028,334 		JBrowse link
G MECP2 methyl-CpG binding protein 2 involved_in ISO
IEA		 RGD
Ensembl		 PMID:23246732 GO_REF:0000107 RGD:9588316 NCBI chr  X:154,021,573...154,097,717
Ensembl chr  X:154,021,573...154,137,103 		JBrowse link
G NCAM1 neural cell adhesion molecule 1 ISO RGD PMID:18499259 RGD:2326016 NCBI chr11:112,961,420...113,278,436
Ensembl chr11:112,961,275...113,278,436 		JBrowse link
G NOS1 nitric oxide synthase 1 ISO RGD PMID:19524414 RGD:5132593 NCBI chr12:117,208,142...117,361,626
Ensembl chr12:117,208,142...117,452,170 		JBrowse link
G NOS3 nitric oxide synthase 3 ISO RGD PMID:17403586 PMID:19524414 RGD:2292145 RGD:5132593 NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588 		JBrowse link
G PLSCR1 phospholipid scramblase 1 involved_in IDA (PMID:29748552) UniProt PMID:29748552 NCBI chr 3:146,515,180...146,544,607
Ensembl chr 3:146,515,180...146,544,856 		JBrowse link
G PPP1CA protein phosphatase 1 catalytic subunit alpha involved_in IEA
ISS		 Ensembl
ARUK-UCL		 GO_REF:0000024 GO_REF:0000107 NCBI chr11:67,398,183...67,401,858
Ensembl chr11:67,398,181...67,421,183 		JBrowse link
G PPP2CA protein phosphatase 2 catalytic subunit alpha involved_in ISS
TAS		 (PMID:22387731) ARUK-UCL PMID:22387731 GO_REF:0000024 NCBI chr 5:134,194,332...134,226,073
Ensembl chr 5:134,194,035...134,226,073 		JBrowse link
G PPP2CB protein phosphatase 2 catalytic subunit beta involved_in IEA
ISS		 Ensembl
ARUK-UCL		 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:30,785,616...30,812,818
Ensembl chr 8:30,774,457...30,814,314 		JBrowse link
G PPP5C protein phosphatase 5 catalytic subunit involved_in ISO
ISS		 RGD
ARUK-UCL		 PMID:23134599 GO_REF:0000024 RGD:8694077 NCBI chr19:46,347,087...46,390,975
Ensembl chr19:46,347,087...46,392,981 		JBrowse link
G PTH parathyroid hormone involved_in ISO
IEA		 RGD
Ensembl		 PMID:23376407 GO_REF:0000107 RGD:7242792 NCBI chr11:13,492,054...13,496,181
Ensembl chr11:13,492,054...13,496,181 		JBrowse link
G QDPR quinoid dihydropteridine reductase ISO RGD PMID:3815851 RGD:5128602 NCBI chr 4:17,486,395...17,512,090
Ensembl chr 4:17,460,261...17,512,206 		JBrowse link
G SERPINA1 serpin family A member 1 ISO RGD PMID:11392791 RGD:1643167 NCBI chr14:94,376,747...94,390,635
Ensembl chr14:94,376,747...94,390,693 		JBrowse link
G SLC11A2 solute carrier family 11 member 2 ISO RGD PMID:19083094 RGD:2311406 NCBI chr12:50,952,263...51,028,886
Ensembl chr12:50,979,401...51,028,566 		JBrowse link
G SLC34A1 solute carrier family 34 member 1 involved_in IDA (PMID:8898024) UniProt PMID:8898024 NCBI chr 5:177,384,434...177,398,848
Ensembl chr 5:177,379,235...177,398,848 		JBrowse link
G SLC6A1 solute carrier family 6 member 1 involved_in ISO
IEA		 RGD
Ensembl		 PMID:15149801 GO_REF:0000107 RGD:1643208 NCBI chr 3:10,992,748...11,039,247
Ensembl chr 3:10,992,186...11,039,247 		JBrowse link
G SPARC secreted protein acidic and cysteine rich ISO RGD PMID:1412468 RGD:2300078 NCBI chr 5:151,661,096...151,686,915
Ensembl chr 5:151,661,096...151,686,975 		JBrowse link
G SREBF2 sterol regulatory element binding transcription factor 2 ISO RGD PMID:16705668 RGD:2308832 NCBI chr22:41,833,105...41,907,305
Ensembl chr22:41,833,105...41,907,306 		JBrowse link
G STAR steroidogenic acute regulatory protein ISO RGD PMID:14514953 RGD:1600082 NCBI chr 8:38,142,700...38,150,952
Ensembl chr 8:38,142,700...38,150,992 		JBrowse link
G TF transferrin ISO RGD PMID:23007736 RGD:7244378 NCBI chr 3:133,661,998...133,796,641
Ensembl chr 3:133,746,040...133,796,641 		JBrowse link
cellular response to lead ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALAD aminolevulinate dehydratase involved_in ISO
IEA		 lead, gallium RGD
Ensembl		 PMID:16566714 GO_REF:0000107 RGD:4144781 NCBI chr 9:113,386,312...113,401,284
Ensembl chr 9:113,386,312...113,401,290 		JBrowse link
G ANXA5 annexin A5 ISO RGD PMID:11578147 RGD:10053705 NCBI chr 4:121,667,946...121,696,980
Ensembl chr 4:121,667,946...121,696,995 		JBrowse link
G ATP7A ATPase copper transporting alpha involved_in ISO
IEA		 RGD
Ensembl		 PMID:24316150 GO_REF:0000107 RGD:11341684 NCBI chr  X:77,910,693...78,050,395
Ensembl chr  X:77,910,690...78,050,395 		JBrowse link
G CLDN1 claudin 1 involved_in ISO
IEA		 RGD
Ensembl		 PMID:17439918 GO_REF:0000107 RGD:11344879 NCBI chr 3:190,305,707...190,322,446
Ensembl chr 3:190,305,707...190,322,446 		JBrowse link
G DNMT1 DNA methyltransferase 1 ISO RGD PMID:22764079 RGD:9588241 NCBI chr19:10,133,346...10,194,953
Ensembl chr19:10,133,342...10,231,286 		JBrowse link
G HMBS hydroxymethylbilane synthase ISO RGD PMID:16566714 RGD:4144781 NCBI chr11:119,084,881...119,093,549
Ensembl chr11:119,084,866...119,093,834 		JBrowse link
G HNRNPK heterogeneous nuclear ribonucleoprotein K ISO RGD PMID:33576715 RGD:155582212 NCBI chr 9:83,968,083...83,980,615
Ensembl chr 9:83,968,083...83,980,631 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 involved_in ISO
IEA		 RGD
Ensembl		 PMID:25193092 GO_REF:0000107 RGD:13207490 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G UCP2 uncoupling protein 2 involved_in ISO
IEA		 RGD
Ensembl		 PMID:33576715 GO_REF:0000107 RGD:155582212 NCBI chr11:73,974,672...73,983,202
Ensembl chr11:73,974,672...73,982,843 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19670
    response to stimulus 10180
      response to chemical 5119
        response to inorganic substance 854
          response to metal ion 558
            response to lead ion 49
              cellular response to lead ion 9
paths to the root