Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: CPOX (coproporphyrinogen oxidase) Homo sapiens
Analyze
Symbol: CPOX
Name: coproporphyrinogen oxidase
Description: Exhibits protein homodimerization activity. Predicted to be involved in protoporphyrinogen IX biosynthetic process. Localizes to cytosol and mitochondrion. Implicated in hereditary coproporphyria and liver disease.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: coprogen oxidase; coproporphyrinogen-III oxidase, mitochondrial; coproporphyrinogenase; COX; CPO; CPX; HCP; homozygous coproporphyria; oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial
Orthologs:
Mus musculus (house mouse) : Cpox (coproporphyrinogen oxidase)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cpox (coproporphyrinogen oxidase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cpox (coproporphyrinogen oxidase)
Pan paniscus (bonobo/pygmy chimpanzee) : CPOX (coproporphyrinogen oxidase)
Canis lupus familiaris (dog) : CPOX (coproporphyrinogen oxidase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cpox (coproporphyrinogen oxidase)
Sus scrofa (pig) : CPOX (coproporphyrinogen oxidase)
Chlorocebus sabaeus (African green monkey) : CPOX (coproporphyrinogen oxidase)
Heterocephalus glaber (naked mole-rat) : Cpox (coproporphyrinogen oxidase)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl398,579,446 - 98,593,648 (-)EnsemblGRCh38hg38GRCh38
GRCh38398,569,837 - 98,593,684 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37398,296,677 - 98,312,470 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36399,780,980 - 99,795,131 (-)NCBINCBI36hg18NCBI36
Build 34399,780,981 - 99,795,131NCBI
Celera396,689,942 - 96,704,107 (-)NCBI
Cytogenetic Map3q11.2NCBI
HuRef395,670,419 - 95,684,588 (-)NCBIHuRef
CHM1_1398,261,466 - 98,275,631 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on CPOX
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1323470
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.