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ONTOLOGY REPORT - ANNOTATIONS

Term:actin filament
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Accession:GO:0005884 term browser browse the term
Definition:A filamentous structure formed of a two-stranded helical polymer of the protein actin and associated proteins. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells. The filaments, comprising polymerized globular actin molecules, appear as flexible structures with a diameter of 5-9 nm. They are organized into a variety of linear bundles, two-dimensional networks, and three dimensional gels. In the cytoskeleton they are most highly concentrated in the cortex of the cell just beneath the plasma membrane.
Synonyms:exact_synonym: microfilament
 xref: FMA:63850;   NIF_Subcellular:sao1588493326;   Wikipedia:Actin


show annotations for term's descendants           Sort by:
actin filament term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABI2 abl interactor 2 located_in ISO (PMID:15572692) UniProt PMID:15572692 NCBI chr15:106,776,627...106,903,889
Ensembl chr15:106,776,631...106,900,333 		JBrowse link
G ACKR2 atypical chemokine receptor 2 located_in IEA Ensembl GO_REF:0000107 NCBI chr13:26,291,583...26,329,506
Ensembl chr13:26,288,584...26,329,581 		JBrowse link
G ACTA1 actin alpha 1, skeletal muscle located_in
is_active_in		 ISS
IBA
IEA		 UniProt
GO_Central
TreeGrafter
Ensembl		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr14:60,412,651...60,415,687
Ensembl chr14:60,412,812...60,415,674 		JBrowse link
G ACTB actin beta is_active_in IBA GO_Central GO_REF:0000033 NCBI chr 3:4,084,275...4,090,383
Ensembl chr 3:4,082,216...4,090,356 		JBrowse link
G ACTBL2 actin beta like 2 is_active_in
located_in		 IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr16:36,469,062...36,471,776
Ensembl chr16:36,470,503...36,471,739 		JBrowse link
G ACTC1 actin alpha cardiac muscle 1 located_in
is_active_in		 IEA
IBA		 Ensembl
GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:136,281,119...136,286,551
Ensembl chr 1:136,281,167...136,286,547 		JBrowse link
G ACTG1 actin gamma 1 located_in
is_active_in		 IEA
IBA		 Ensembl
TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr12:1,320,355...1,323,219
Ensembl chr12:1,313,641...1,323,217 		JBrowse link
G ACTL9 actin like 9 is_active_in IBA GO_Central GO_REF:0000033 NCBI chr 2:70,658,141...70,659,497
Ensembl chr 2:70,658,247...70,659,497 		JBrowse link
G ACTN1 actinin alpha 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr 7:92,550,132...92,644,842
Ensembl chr 7:92,550,007...92,644,842 		JBrowse link
G ACTR3 actin related protein 3 located_in ISO RGD PMID:10209028 RGD:2306208 NCBI chr15:20,104,808...20,171,721
Ensembl chr15:20,104,812...20,167,421 		JBrowse link
G AFAP1 actin filament associated protein 1 ISO RGD PMID:12114187 RGD:625602 NCBI chr 8:3,070,031...3,198,319
Ensembl chr 8:3,069,959...3,202,533 		JBrowse link
G AIF1 allograft inflammatory factor 1 located_in IEA
IBA
ISS		 Ensembl
GO_Central
TreeGrafter
UniProt		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 7:23,711,752...23,731,191
Ensembl chr 7:23,726,787...23,731,671 		JBrowse link
G AIF1L allograft inflammatory factor 1 like located_in IEA
IBA		 Ensembl
GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:271,075,376...271,099,984
Ensembl chr 1:271,072,734...271,102,803 		JBrowse link
G AKAP13 A-kinase anchoring protein 13 located_in ISO (MGI:5308772|PMID:20139090) UniProt PMID:20139090 MGI:5308772 NCBI chr 7:87,889,384...88,222,854 JBrowse link
G AMOT angiomotin located_in IEA Ensembl GO_REF:0000107 NCBI chr  X:92,581,995...92,647,872
Ensembl chr  X:92,582,047...92,647,857 		JBrowse link
G ANXA1 annexin A1 located_in IEA Ensembl GO_REF:0000107 NCBI chr 1:226,414,200...226,431,963
Ensembl chr 1:226,414,306...226,432,279 		JBrowse link
G APC2 APC regulator of WNT signaling pathway 2 located_in IEA Ensembl GO_REF:0000107 NCBI chr 2:77,005,706...77,034,583
Ensembl chr 2:77,005,706...77,034,561 		JBrowse link
G ARPP19 cAMP regulated phosphoprotein 19 located_in IEA Ensembl GO_REF:0000107 NCBI chr 1:119,134,318...119,157,169
Ensembl chr 1:119,134,851...119,157,352 		JBrowse link
G AVIL advillin located_in IEA Ensembl GO_REF:0000107 NCBI chr 5:23,087,946...23,110,602
Ensembl chr 5:23,087,956...23,110,602 		JBrowse link
G CALD1 caldesmon 1 ISO RGD PMID:3384851 RGD:2303065 NCBI chr18:14,267,955...14,486,641
Ensembl chr18:14,267,959...14,486,726 		JBrowse link
G CD2AP CD2 associated protein located_in
is_active_in		 IEA
ISO		 (PMID:17606992) Ensembl
MGI		 PMID:17606992 GO_REF:0000107 NCBI chr 7:42,218,016...42,332,523
Ensembl chr 7:42,218,290...42,332,518 		JBrowse link
G CNN1 calponin 1 is_active_in IBA GO_Central GO_REF:0000033 NCBI chr 2:70,183,370...70,190,756
Ensembl chr 2:70,183,364...70,190,752 		JBrowse link
G CNN2 calponin 2 is_active_in IBA GO_Central GO_REF:0000033 NCBI chr 2:77,376,020...77,385,594
Ensembl chr 2:77,375,983...77,385,571 		JBrowse link
G COBL cordon-bleu WH2 repeat protein located_in IEA TreeGrafter GO_REF:0000118 NCBI chr 9:136,850,521...137,055,249 JBrowse link
G CORO1A coronin 1A located_in IEA Ensembl GO_REF:0000107 NCBI chr 3:18,336,813...18,342,381
Ensembl chr 3:18,336,898...18,342,396 		JBrowse link
G CORO1B coronin 1B located_in IEA Ensembl GO_REF:0000107 NCBI chr 2:5,081,294...5,086,698
Ensembl chr 2:5,080,660...5,086,690 		JBrowse link
G COTL1 coactosin like F-actin binding protein 1 located_in IEA TreeGrafter GO_REF:0000118 NCBI chr 6:4,099,341...4,146,281
Ensembl chr 6:4,099,414...4,147,469 		JBrowse link
G CTTN cortactin located_in IEA
IBA		 Ensembl
GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 2:3,031,103...3,060,796
Ensembl chr 2:3,031,103...3,060,813 		JBrowse link
G DAPK3 death associated protein kinase 3 ISO RGD PMID:10602480 RGD:8554171 NCBI chr 2:74,758,962...74,776,355
Ensembl chr 2:74,759,004...74,775,330 		JBrowse link
G DBN1 drebrin 1 located_in IEA
IBA		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr 2:80,480,603...80,495,797
Ensembl chr 2:80,479,460...80,495,796 		JBrowse link
G DBNL drebrin like located_in IEA
IBA		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr18:48,713,335...48,725,692
Ensembl chr18:48,713,340...48,725,697 		JBrowse link
G DIAPH1 diaphanous related formin 1 located_in IEA TreeGrafter GO_REF:0000118 NCBI chr 2:143,158,691...143,271,110
Ensembl chr 2:143,158,585...143,271,147 		JBrowse link
G DIAPH2 diaphanous related formin 2 located_in
is_active_in		 IEA
IBA		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr  X:78,602,385...79,520,441
Ensembl chr  X:78,602,390...79,520,428 		JBrowse link
G DIAPH3 diaphanous related formin 3 located_in
is_active_in		 IEA
IBA		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr11:32,492,735...32,994,854
Ensembl chr11:32,492,740...32,994,844 		JBrowse link
G DLC1 DLC1 Rho GTPase activating protein located_in ISO RGD PMID:15506980 RGD:1624304 NCBI chr17:1,169,709...1,637,171
Ensembl chr17:1,170,208...1,637,114 		JBrowse link
G DMTN dematin actin binding protein located_in IEA Ensembl GO_REF:0000107 NCBI chr14:6,315,643...6,346,722
Ensembl chr14:6,321,870...6,346,865 		JBrowse link
G DNAJA3 DnaJ heat shock protein family (Hsp40) member A3 located_in IEA Ensembl GO_REF:0000107 NCBI chr 3:37,883,233...37,919,141
Ensembl chr 3:37,883,244...37,919,324 		JBrowse link
G DYRK1A dual specificity tyrosine phosphorylation regulated kinase 1A located_in ISO (PMID:24327345) ARUK-UCL PMID:24327345 NCBI chr13:201,008,506...201,159,946
Ensembl chr13:201,009,480...201,159,948 		JBrowse link
G EZR ezrin located_in IEA Ensembl GO_REF:0000107 NCBI chr 1:8,403,362...8,452,750
Ensembl chr 1:8,403,453...8,452,742 		JBrowse link
G FHDC1 FH2 domain containing 1 is_active_in
located_in		 IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr 8:76,103,631...76,148,690
Ensembl chr 8:76,106,192...76,143,682 		JBrowse link
G FLNA filamin A located_in ISO RGD PMID:15661894 PMID:22872576 RGD:2312435 RGD:7207404 NCBI chr  X:124,889,934...124,915,000
Ensembl chr  X:124,890,162...124,914,992 		JBrowse link
G FMN1 formin 1 located_in IEA InterPro GO_REF:0000002 NCBI chr 1:136,696,353...137,163,532
Ensembl chr 1:136,704,090...137,065,258 		JBrowse link
G FYN FYN proto-oncogene, Src family tyrosine kinase located_in ISO (PMID:17623777) MGI PMID:17623777 NCBI chr 1:77,584,675...77,810,605
Ensembl chr 1:77,585,439...77,810,581 		JBrowse link
G GAS2 growth arrest specific 2 located_in IEA TreeGrafter GO_REF:0000118 NCBI chr 2:36,712,758...36,885,436
Ensembl chr 2:36,711,612...36,885,620 		JBrowse link
G GAS2L1 growth arrest specific 2 like 1 is_active_in
located_in		 IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr14:46,449,767...46,455,278
Ensembl chr14:46,449,787...46,455,276 		JBrowse link
G GAS2L2 growth arrest specific 2 like 2 located_in
is_active_in		 IEA
IBA		 Ensembl
TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr12:39,772,070...39,785,159
Ensembl chr12:39,773,707...39,783,553 		JBrowse link
G GAS2L3 growth arrest specific 2 like 3 is_active_in
located_in		 IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr 5:83,558,816...83,600,725
Ensembl chr 5:83,560,962...83,600,329 		JBrowse link
G GAS7 growth arrest specific 7 located_in IEA TreeGrafter GO_REF:0000118 NCBI chr12:54,752,436...54,974,535
Ensembl chr12:54,752,507...54,973,515 		JBrowse link
G GDPD2 glycerophosphodiester phosphodiesterase domain containing 2 located_in IEA Ensembl GO_REF:0000107 NCBI chr  X:56,449,430...56,460,399
Ensembl chr  X:56,449,425...56,460,392 		JBrowse link
G GJB6 gap junction protein beta 6 located_in IEA Ensembl GO_REF:0000107 NCBI chr11:793,276...800,109
Ensembl chr11:793,280...800,046 		JBrowse link
G GNG12 G protein subunit gamma 12 located_in ISO RGD PMID:9492299 RGD:2314449 NCBI chr 6:144,782,478...144,918,556
Ensembl chr 6:144,782,503...144,918,549 		JBrowse link
G HCK HCK proto-oncogene, Src family tyrosine kinase located_in IEA Ensembl GO_REF:0000107 NCBI chr17:35,708,549...35,751,590
Ensembl chr17:35,709,349...35,751,582 		JBrowse link
G HCLS1 hematopoietic cell-specific Lyn substrate 1 located_in IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr13:138,852,387...138,883,088
Ensembl chr13:138,855,144...138,889,281 		JBrowse link
G INPP5D inositol polyphosphate-5-phosphatase D ISO RGD PMID:15661894 RGD:2312435 NCBI chr15:133,501,067...133,626,647
Ensembl chr15:133,501,092...133,626,644 		JBrowse link
G KEAP1 kelch like ECH associated protein 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr 2:69,280,940...69,290,267
Ensembl chr 2:69,276,336...69,294,382 		JBrowse link
G LCP1 lymphocyte cytosolic protein 1 located_in
is_active_in		 IEA
IBA		 Ensembl
TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr11:21,126,504...21,223,543
Ensembl chr11:21,126,539...21,223,550 		JBrowse link
G LMOD1 leiomodin 1 located_in ISO PMID:10520227 UniProt PMID:10520227 RGD:11344950 NCBI chr10:24,165,293...24,194,823
Ensembl chr10:24,164,792...24,193,820 		JBrowse link
G LMOD2 leiomodin 2 located_in IEA Ensembl GO_REF:0000107 NCBI chr18:23,803,927...23,815,772
Ensembl chr18:23,803,682...23,812,479 		JBrowse link
G LOC100620599 tropomyosin alpha-3 chain is_active_in
located_in		 IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118
G MARK2 microtubule affinity regulating kinase 2 located_in IEA Ensembl GO_REF:0000107 NCBI chr 2:8,153,870...8,216,141
Ensembl chr 2:8,155,348...8,215,959 		JBrowse link
G MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 located_in
is_active_in		 IEA
ISO		 (PMID:33393173) Ensembl
UniProt		 PMID:33393173 GO_REF:0000107 NCBI chr 1:75,511,692...75,522,760
Ensembl chr 1:75,511,693...75,522,765 		JBrowse link
G MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 is_active_in ISO (PMID:29343822) UniProt PMID:29343822 NCBI chr 2:47,042,475...47,302,087
Ensembl chr 2:47,131,832...47,302,117 		JBrowse link
G MISP mitotic spindle positioning located_in IEA Ensembl GO_REF:0000107 NCBI chr 2:77,607,185...77,619,124
Ensembl chr 2:77,602,142...77,619,087 		JBrowse link
G MYH9 myosin heavy chain 9 ISO RGD PMID:21598299 RGD:12798522 NCBI chr 5:11,365,603...11,456,475
Ensembl chr 5:11,360,660...11,456,472 		JBrowse link
G MYO1B myosin IB located_in IEA Ensembl GO_REF:0000107 NCBI chr15:95,874,398...96,066,408
Ensembl chr15:95,874,412...96,066,990 		JBrowse link
G MYO5A myosin VA located_in IEA Ensembl GO_REF:0000107 NCBI chr 1:119,165,751...119,398,591
Ensembl chr 1:119,165,942...119,394,725 		JBrowse link
G MYO6 myosin VI located_in IMP (PMID:12857860) UniProt PMID:12857860 NCBI chr 1:89,992,860...90,137,767
Ensembl chr 1:89,992,866...90,137,734 		JBrowse link
G MYO9A myosin IXA located_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:169,370,028...169,596,771
Ensembl chr 1:169,374,311...169,596,412 		JBrowse link
G MYO9B myosin IXB is_active_in
located_in		 ISO
IBA
IEA		 RGD
GO_Central
TreeGrafter
Ensembl		 PMID:9348541 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 RGD:1581711 NCBI chr 2:60,455,605...60,567,479
Ensembl chr 2:60,455,607...60,567,467 		JBrowse link
G NCBP1 nuclear cap binding protein subunit 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr 1:239,375,150...239,468,387
Ensembl chr 1:239,396,097...239,467,758 		JBrowse link
G PAK1 p21 (RAC1) activated kinase 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr 9:11,830,095...11,973,074
Ensembl chr 9:11,830,095...12,020,415 		JBrowse link
G PALLD palladin, cytoskeletal associated protein located_in IEA Ensembl GO_REF:0000107 NCBI chr14:20,678,456...21,020,125
Ensembl chr14:20,678,452...21,020,125 		JBrowse link
G PAWR pro-apoptotic WT1 regulator located_in ISO PMID:16229834 UniProt
RGD		 PMID:15817164 PMID:16229834 RGD:8554822 RGD:9835355 NCBI chr 5:101,693,145...101,797,842
Ensembl chr 5:101,693,246...101,797,838 		JBrowse link
G PLS1 plastin 1 located_in IEA TreeGrafter GO_REF:0000118 NCBI chr13:83,307,692...83,434,133
Ensembl chr13:83,308,007...83,434,128 		JBrowse link
G PLS3 plastin 3 located_in
is_active_in		 IEA
IBA		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr  X:94,885,098...94,971,664
Ensembl chr  X:94,885,118...94,971,659 		JBrowse link
G POF1B POF1B actin binding protein located_in
is_active_in		 IEA
IBA		 Ensembl
TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr  X:68,503,170...68,579,917
Ensembl chr  X:68,503,179...68,579,893 		JBrowse link
G PSTPIP1 proline-serine-threonine phosphatase interacting protein 1 located_in IEA TreeGrafter GO_REF:0000118 NCBI chr 7:57,100,212...57,145,278
Ensembl chr 7:57,102,757...57,146,751 		JBrowse link
G PSTPIP2 proline-serine-threonine phosphatase interacting protein 2 located_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:95,631,456...95,727,827
Ensembl chr 1:95,631,456...95,727,782 		JBrowse link
G PTGES3 prostaglandin E synthase 3 ISO RGD PMID:8864660 RGD:5688126 NCBI chr 5:22,000,335...22,022,830
Ensembl chr 5:22,000,341...22,021,660 		JBrowse link
G RAC1 Rac family small GTPase 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr 3:4,781,776...4,803,510
Ensembl chr 3:4,781,780...4,803,543 		JBrowse link
G RAC2 Rac family small GTPase 2 located_in IEA Ensembl GO_REF:0000107 NCBI chr 5:10,553,986...10,571,082
Ensembl chr 5:10,553,433...10,573,014 		JBrowse link
G RHOQ ras homolog family member Q located_in IEA Ensembl GO_REF:0000107 NCBI chr 3:93,970,545...94,012,660
Ensembl chr 3:93,973,653...94,012,580 		JBrowse link
G RSL1D1 ribosomal L1 domain containing 1 located_in IBA GO_Central GO_REF:0000033 NCBI chr 3:31,278,394...31,291,205
Ensembl chr 3:31,278,852...31,293,246 		JBrowse link
G SGIP1 SH3GL interacting endocytic adaptor 1 located_in IEA TreeGrafter GO_REF:0000118 NCBI chr 6:145,815,658...146,051,621
Ensembl chr 6:145,822,269...146,052,526 		JBrowse link
G SH2B2 SH2B adaptor protein 2 located_in IEA Ensembl GO_REF:0000107 NCBI chr 3:9,670,838...9,695,325
Ensembl chr 3:9,670,815...9,695,629 		JBrowse link
G SHROOM4 shroom family member 4 located_in IEA Ensembl GO_REF:0000107 NCBI chr  X:44,301,956...44,543,969
Ensembl chr  X:44,332,620...44,543,337 		JBrowse link
G SPTBN4 spectrin beta, non-erythrocytic 4 located_in ISO (MGI:2181223|PMID:11807096) BHF-UCL PMID:11807096 MGI:2181223 NCBI chr 6:48,729,839...48,812,799
Ensembl chr 6:48,729,419...48,812,796 		JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase located_in IEA Ensembl GO_REF:0000107 NCBI chr17:40,470,970...40,524,862
Ensembl chr17:40,471,009...40,524,860 		JBrowse link
G TEK TEK receptor tyrosine kinase located_in IEA Ensembl GO_REF:0000107 NCBI chr 1:195,938,177...196,052,294
Ensembl chr 1:195,937,432...196,051,980 		JBrowse link
G TFPT TCF3 fusion partner located_in ISO PMID:16229834 UniProt PMID:16229834 RGD:8554822 NCBI chr 6:56,011,496...56,018,166
Ensembl chr 6:56,011,491...56,018,169 		JBrowse link
G TPM1 tropomyosin 1 is_active_in
located_in		 IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr 1:108,986,981...109,016,090
Ensembl chr 1:108,986,986...109,020,035 		JBrowse link
G TPM2 tropomyosin 2 is_active_in
located_in		 IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr 1:236,402,249...236,410,390
Ensembl chr 1:236,402,251...236,410,905 		JBrowse link
G TPM3 tropomyosin 3 is_active_in
located_in		 IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr 4:95,542,329...95,572,946
Ensembl chr 4:95,542,473...95,572,938 		JBrowse link
G TPM4 tropomyosin 4 is_active_in
located_in		 IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr 2:61,453,721...61,476,781
Ensembl chr 2:61,453,725...61,476,781 		JBrowse link
G TSC1 TSC complex subunit 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr 1:272,636,530...272,685,948
Ensembl chr 1:272,636,532...272,685,951 		JBrowse link
G TWF1 twinfilin actin binding protein 1 located_in IEA TreeGrafter GO_REF:0000118 NCBI chr 5:74,868,586...74,881,220
Ensembl chr 5:74,868,585...74,893,698 		JBrowse link
G TWF2 twinfilin actin binding protein 2 located_in
is_active_in		 IEA
IBA		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr13:34,361,294...34,370,997
Ensembl chr13:34,361,297...34,371,277 		JBrowse link
G VCL vinculin located_in ISO RGD PMID:15506980 RGD:1624304 NCBI chr14:76,700,143...76,811,875
Ensembl chr14:76,700,173...76,811,869 		JBrowse link
G VPS11 VPS11 core subunit of CORVET and HOPS complexes located_in IEA Ensembl GO_REF:0000107 NCBI chr 9:46,285,718...46,297,465
Ensembl chr 9:46,285,739...46,297,474 		JBrowse link
G VPS16 VPS16 core subunit of CORVET and HOPS complexes located_in ISO (PMID:14668490) MGI PMID:14668490 NCBI chr17:32,803,596...32,825,974
Ensembl chr17:32,803,412...32,825,933 		JBrowse link
G VPS18 VPS18 core subunit of CORVET and HOPS complexes located_in IEA Ensembl GO_REF:0000107 NCBI chr 1:130,409,121...130,420,467
Ensembl chr 1:130,409,123...130,420,450 		JBrowse link
G WAS WASP actin nucleation promoting factor located_in IEA Ensembl GO_REF:0000107 NCBI chr  X:42,774,597...42,793,055
Ensembl chr  X:42,774,588...42,793,055 		JBrowse link
G WASL WASP like actin nucleation promoting factor located_in IEA TreeGrafter GO_REF:0000118 NCBI chr18:23,722,188...23,789,516
Ensembl chr18:23,722,188...23,789,506 		JBrowse link
G WHRN whirlin located_in IEA Ensembl GO_REF:0000107 NCBI chr 1:255,009,765...255,095,281
Ensembl chr 1:255,009,771...255,095,222 		JBrowse link
G WIPF1 WAS/WASL interacting protein family member 1 located_in
is_active_in		 ISO
IBA		 (PMID:22966049) RGD
MGI
GO_Central		 PMID:11687573 PMID:22966049 GO_REF:0000033 RGD:634538 NCBI chr15:80,521,032...80,646,462 JBrowse link
G YES1 YES proto-oncogene 1, Src family tyrosine kinase located_in ISO (PMID:17623777) MGI PMID:17623777 NCBI chr 6:105,505,944...105,600,694
Ensembl chr 6:105,505,479...105,600,687 		JBrowse link
actin filament branch point term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARPC2 actin related protein 2/3 complex subunit 2 ISO RGD PMID:18256280 RGD:2306202 NCBI chr15:120,297,122...120,328,795
Ensembl chr15:120,297,025...120,328,542 		JBrowse link
filamentous actin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTG1 actin gamma 1 part_of IEA Ensembl GO_REF:0000107 NCBI chr12:1,320,355...1,323,219
Ensembl chr12:1,313,641...1,323,217 		JBrowse link
G APC2 APC regulator of WNT signaling pathway 2 part_of
located_in		 IEA
ISO		 (PMID:25753423) Ensembl
UniProt		 PMID:25753423 GO_REF:0000107 NCBI chr 2:77,005,706...77,034,583
Ensembl chr 2:77,005,706...77,034,561 		JBrowse link
G ARPC2 actin related protein 2/3 complex subunit 2 ISO RGD PMID:10797548 RGD:11049163 NCBI chr15:120,297,122...120,328,795
Ensembl chr15:120,297,025...120,328,542 		JBrowse link
G ARPC3 actin related protein 2/3 complex subunit 3 ISO RGD PMID:10797548 RGD:11049163 NCBI chr14:31,814,382...31,823,452
Ensembl chr14:31,814,151...31,826,855 		JBrowse link
G BLOC1S6 biogenesis of lysosomal organelles complex 1 subunit 6 part_of IEA Ensembl GO_REF:0000107 NCBI chr 1:126,168,944...126,184,813
Ensembl chr 1:126,165,994...126,184,858 		JBrowse link
G CARMIL1 capping protein regulator and myosin 1 linker 1 part_of IEA Ensembl GO_REF:0000107 NCBI chr 7:20,036,430...20,353,431
Ensembl chr 7:20,036,944...20,353,420 		JBrowse link
G CD2AP CD2 associated protein part_of IEA Ensembl GO_REF:0000107 NCBI chr 7:42,218,016...42,332,523
Ensembl chr 7:42,218,290...42,332,518 		JBrowse link
G DIAPH3 diaphanous related formin 3 part_of IEA Ensembl GO_REF:0000107 NCBI chr11:32,492,735...32,994,854
Ensembl chr11:32,492,740...32,994,844 		JBrowse link
G DPYSL3 dihydropyrimidinase like 3 part_of ISO PMID:16181627 UniProt PMID:16181627 RGD:8553533 NCBI chr 2:148,663,563...148,777,055
Ensembl chr 2:148,662,051...148,776,619 		JBrowse link
G DUSP22 dual specificity phosphatase 22 part_of IEA Ensembl GO_REF:0000107 NCBI chr 7:43,437...96,270
Ensembl chr 7:43,487...96,267 		JBrowse link
G EHBP1 EH domain binding protein 1 part_of IEA TreeGrafter GO_REF:0000118 NCBI chr 3:78,907,315...79,261,890
Ensembl chr 3:78,907,317...79,257,760 		JBrowse link
G EHBP1L1 EH domain binding protein 1 like 1 part_of IEA TreeGrafter GO_REF:0000118 NCBI chr 2:6,662,460...6,678,721
Ensembl chr 2:6,662,463...6,678,888 		JBrowse link
G ESPN espin part_of ISO PMID:8799813 UniProt PMID:8799813 RGD:632658 NCBI chr 6:67,284,106...67,316,577
Ensembl chr 6:67,284,079...67,316,591 		JBrowse link
G JAM3 junctional adhesion molecule 3 part_of IEA Ensembl GO_REF:0000107 NCBI chr 9:60,629,245...60,738,979
Ensembl chr 9:60,613,400...60,738,924 		JBrowse link
G KPTN kaptin, actin binding protein part_of
located_in		 IEA
ISO		 (PMID:24239382) Ensembl
UniProt		 PMID:24239382 GO_REF:0000107 NCBI chr 6:53,238,650...53,246,458
Ensembl chr 6:53,238,666...53,249,163 		JBrowse link
G LDB3 LIM domain binding 3 part_of IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr14:87,660,961...87,722,249
Ensembl chr14:87,644,242...87,722,251 		JBrowse link
G MAP3K1 mitogen-activated protein kinase kinase kinase 1 part_of ISO (PMID:25224220) MGI PMID:25224220 NCBI chr16:35,872,301...35,947,097
Ensembl chr16:35,872,131...35,946,987 		JBrowse link
G MICALL1 MICAL like 1 part_of IEA TreeGrafter GO_REF:0000118 NCBI chr 5:9,924,648...9,956,998
Ensembl chr 5:9,924,652...9,956,946 		JBrowse link
G MYO18B myosin XVIIIB part_of IEA Ensembl GO_REF:0000107 NCBI chr14:43,467,823...43,687,729
Ensembl chr14:43,468,514...43,687,727 		JBrowse link
G MYO1A myosin IA part_of IEA Ensembl GO_REF:0000107 NCBI chr 5:22,338,024...22,363,528
Ensembl chr 5:22,338,029...22,363,568 		JBrowse link
G MYO1C myosin IC part_of IEA Ensembl GO_REF:0000107 NCBI chr12:47,691,252...47,715,670
Ensembl chr12:47,691,256...47,718,337 		JBrowse link
G MYO1F myosin IF part_of ISO (PMID:17023661) MGI PMID:17023661 NCBI chr 2:70,753,143...70,792,938
Ensembl chr 2:70,753,138...70,792,936 		JBrowse link
G MYO3A myosin IIIA part_of ISO (PMID:12672820) UniProt PMID:12672820 NCBI chr10:49,392,119...49,623,575 JBrowse link
G MYO6 myosin VI part_of IDA
IEA		 (PMID:10519557) UniProt
Ensembl		 PMID:10519557 GO_REF:0000107 NCBI chr 1:89,992,860...90,137,767
Ensembl chr 1:89,992,866...90,137,734 		JBrowse link
G NCKAP1 NCK associated protein 1 part_of ISO (MGI:5897521|PMID:27927633) BHF-UCL PMID:27927633 MGI:5897521 NCBI chr15:88,425,861...88,528,417
Ensembl chr15:88,425,142...88,528,326 		JBrowse link
G PDLIM1 PDZ and LIM domain 1 part_of IEA
IBA		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr14:106,744,320...106,793,606
Ensembl chr14:106,735,500...106,794,065 		JBrowse link
G PDLIM2 PDZ and LIM domain 2 part_of IEA TreeGrafter GO_REF:0000118 NCBI chr14:6,834,116...6,848,536
Ensembl chr14:6,834,779...6,848,526 		JBrowse link
G PDLIM3 PDZ and LIM domain 3 part_of IEA
IBA		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr15:46,516,178...46,546,658
Ensembl chr15:46,513,449...46,546,507 		JBrowse link
G PDLIM4 PDZ and LIM domain 4 part_of IEA
IBA		 Ensembl
GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 2:134,555,367...134,570,356
Ensembl chr 2:134,555,666...134,570,348 		JBrowse link
G PDLIM5 PDZ and LIM domain 5 part_of IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr 8:125,044,027...125,259,969
Ensembl chr 8:125,044,028...125,259,945 		JBrowse link
G PDLIM7 PDZ and LIM domain 7 part_of IEA
IBA		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr 2:80,453,013...80,472,660
Ensembl chr 2:80,452,706...80,472,658 		JBrowse link
G RAC3 Rac family small GTPase 3 part_of IEA Ensembl GO_REF:0000107 NCBI chr12:981,072...984,222
Ensembl chr12:981,074...984,227 		JBrowse link
G SMTN smoothelin part_of IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr14:47,879,317...47,902,700
Ensembl chr14:47,879,317...47,902,698 		JBrowse link
G SMTNL1 smoothelin like 1 part_of IEA TreeGrafter GO_REF:0000118 NCBI chr 2:13,370,920...13,384,843 JBrowse link
G SMTNL2 smoothelin like 2 part_of IEA
IBA		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr12:50,582,628...50,602,730
Ensembl chr12:50,582,629...50,602,700 		JBrowse link
G SPECC1 sperm antigen with calponin homology and coiled-coil domains 1 part_of IEA TreeGrafter GO_REF:0000118 NCBI chr12:59,466,778...59,705,602
Ensembl chr12:59,466,791...59,654,192 		JBrowse link
G SPECC1L sperm antigen with calponin homology and coiled-coil domains 1 like part_of IEA TreeGrafter GO_REF:0000118 NCBI chr14:49,332,937...49,463,965
Ensembl chr14:49,333,009...49,463,963 		JBrowse link
G TGFB1I1 transforming growth factor beta 1 induced transcript 1 part_of IEA TreeGrafter GO_REF:0000118 NCBI chr 3:17,093,275...17,099,204
Ensembl chr 3:17,090,116...17,099,020 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 18686
    cellular anatomical entity 18464
      supramolecular complex 1309
        supramolecular polymer 972
          supramolecular fiber 965
            polymeric cytoskeletal fiber 719
              actin filament 139
                actin filament branch point 1
                actin filament of cell cortex of cell tip 0
                actomyosin contractile ring actin filament 0
                filamentous actin 38
Path 2
Term Annotations click to browse term
  cellular_component 18686
    cellular anatomical entity 18464
      organelle 12444
        non-membrane-bounded organelle 4567
          intracellular non-membrane-bounded organelle 4565
            cytoskeleton 2200
              actin cytoskeleton 527
                actin filament 139
                  actin filament branch point 1
                  actin filament of cell cortex of cell tip 0
                  actomyosin contractile ring actin filament 0
                  filamentous actin 38
paths to the root