VPS11 (VPS11 core subunit of CORVET and HOPS complexes) - Rat Genome Database
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Gene: VPS11 (VPS11 core subunit of CORVET and HOPS complexes) Sus scrofa
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Symbol: VPS11
Name: VPS11 core subunit of CORVET and HOPS complexes
RGD ID: 14155022
Description: ENCODES a protein that exhibits protein domain specific binding (ortholog); syntaxin binding (ortholog); ubiquitin protein ligase activity (ortholog); INVOLVED IN endosomal vesicle fusion (ortholog); endosome to lysosome transport (ortholog); negative regulation of intracellular estrogen receptor signaling pathway (ortholog); ASSOCIATED WITH Dwarfism (ortholog); Glycogen Storage Disease IB (ortholog); hypomyelinating leukodystrophy 12 (ortholog); FOUND IN actin filament (ortholog); AP-3 adaptor complex (ortholog); CORVET complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: vacuolar protein sorting-associated protein 11 homolog; VPS11, CORVET/HOPS core subunit
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl946,285,729 - 46,297,465 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1946,285,718 - 46,297,465 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2951,320,856 - 51,332,600 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

Genomics

Comparative Map Data
VPS11
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl946,285,729 - 46,297,465 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1946,285,718 - 46,297,465 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2951,320,856 - 51,332,600 (+)NCBISscrofa10.2Sscrofa10.2susScr3
VPS11
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl11119,067,692 - 119,081,978 (+)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl11119,067,818 - 119,081,972 (+)EnsemblGRCh38hg38GRCh38
GRCh3811119,067,792 - 119,081,972 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3711118,938,493 - 118,952,688 (+)NCBIGRCh37GRCh37hg19GRCh37
GRCh3711118,938,529 - 118,952,682 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3611118,443,703 - 118,457,898 (+)NCBINCBI36hg18NCBI36
Build 3411118,443,702 - 118,457,884NCBI
Celera11116,096,175 - 116,110,109 (+)NCBI
Cytogenetic Map11q23.3NCBI
HuRef11114,878,034 - 114,892,141 (+)NCBIHuRef
CHM1_111118,824,741 - 118,838,977 (+)NCBICHM1_1
Vps11
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39944,259,046 - 44,272,970 (-)NCBIGRCm39mm39
GRCm38944,347,749 - 44,361,673 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl944,347,749 - 44,361,670 (-)EnsemblGRCm38mm10GRCm38
MGSCv37944,156,188 - 44,169,753 (-)NCBIGRCm37mm9NCBIm37
MGSCv36944,099,100 - 44,112,665 (-)NCBImm8
Celera941,603,071 - 41,616,610 (-)NCBICelera
Cytogenetic Map9A5.2NCBI
Vps11
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2844,683,768 - 44,698,572 (-)NCBI
Rnor_6.0 Ensembl848,677,492 - 48,692,295 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0848,677,492 - 48,692,295 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0847,296,463 - 47,311,266 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4847,324,449 - 47,339,252 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1847,333,277 - 47,348,018 (-)NCBI
Celera844,270,001 - 44,284,802 (-)NCBICelera
Cytogenetic Map8q22NCBI
Vps11
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541220,177,623 - 20,190,141 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541220,161,520 - 20,190,141 (+)NCBIChiLan1.0ChiLan1.0
VPS11
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.111117,835,497 - 117,849,389 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11117,835,557 - 117,849,389 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v011113,905,989 - 113,920,163 (+)NCBIMhudiblu_PPA_v0panPan3
VPS11
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl514,776,976 - 14,786,692 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1514,776,975 - 14,786,736 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Vps11
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365424,022,928 - 4,035,577 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
VPS11
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11110,440,681 - 110,455,092 (+)NCBI
ChlSab1.1 Ensembl1110,439,933 - 110,455,844 (+)Ensembl
Vps11
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462478414,452,811 - 14,464,965 (+)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 1 2 3 5 1 22 2 1 3
Low 9 2 1 1 2
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000016473   ⟹   ENSSSCP00000016030
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl946,285,729 - 46,297,465 (+)Ensembl
RefSeq Acc Id: XM_003129923   ⟹   XP_003129971
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1946,285,718 - 46,297,465 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021062957   ⟹   XP_020918616
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1946,285,718 - 46,297,465 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003129971 (Get FASTA)   NCBI Sequence Viewer  
  XP_020918616 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_003129971   ⟸   XM_003129923
- Peptide Label: isoform X1
- UniProtKB: F1SAH7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020918616   ⟸   XM_021062957
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSSSCP00000016030   ⟸   ENSSSCT00000016473
Protein Domains
RING-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000015107 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00070001105 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000016030 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00070001772 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000016473 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00070002121 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.10 UniProtKB/TrEMBL
  2.130.10.10 UniProtKB/TrEMBL
  3.30.40.10 UniProtKB/TrEMBL
InterPro ARM-type_fold UniProtKB/TrEMBL
  Clathrin_H-chain/VPS_repeat UniProtKB/TrEMBL
  TPR-like_helical_dom_sf UniProtKB/TrEMBL
  VPS11 UniProtKB/TrEMBL
  VPS11_C UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom_sf UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/TrEMBL
  Znf_RING UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
KEGG Report ssc:100517049 UniProtKB/TrEMBL
NCBI Gene VPS11 ENTREZGENE
PANTHER PTHR23323:SF24 UniProtKB/TrEMBL
Pfam Clathrin UniProtKB/TrEMBL
  VPS11_C UniProtKB/TrEMBL
PIRSF VPS11 UniProtKB/TrEMBL
PROSITE CHCR UniProtKB/TrEMBL
  ZF_RING_2 UniProtKB/TrEMBL
SMART RING UniProtKB/TrEMBL
Superfamily-SCOP SSF48371 UniProtKB/TrEMBL
  SSF50978 UniProtKB/TrEMBL
UniProt A0A4X1SIU4_PIG UniProtKB/TrEMBL
  F1SAH7 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:94837 ENTREZGENE