MISP (mitotic spindle positioning) - Rat Genome Database

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Gene: MISP (mitotic spindle positioning) Sus scrofa
Analyze
Symbol: MISP
Name: mitotic spindle positioning
RGD ID: 13870595
Description: ENCODES a protein that exhibits actin filament binding (inferred); INVOLVED IN organelle localization (ortholog); ASSOCIATED WITH cerebral creatine deficiency syndrome (ortholog); FOUND IN cortical actin cytoskeleton (ortholog); focal adhesion (ortholog); mitotic spindle astral microtubule end (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: mitotic interactor and substrate of PLK1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl277,602,142 - 77,619,087 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1277,607,185 - 77,619,124 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2278,316,218 - 78,324,105 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

Genomics

Comparative Map Data
MISP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl277,602,142 - 77,619,087 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1277,607,185 - 77,619,124 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2278,316,218 - 78,324,105 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MISP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl19751,112 - 764,318 (+)EnsemblGRCh38hg38GRCh38
GRCh3819748,413 - 764,318 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3719751,112 - 764,318 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3619702,146 - 715,318 (+)NCBINCBI36hg18NCBI36
Build 3419702,145 - 715,319NCBI
Celera1952,059 - 65,229 (-)NCBI
Cytogenetic Map19p13.3NCBI
HuRef19520,795 - 533,963 (+)NCBIHuRef
CHM1_119750,590 - 763,759 (+)NCBICHM1_1
Misp
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391079,656,853 - 79,666,286 (+)NCBIGRCm39mm39
GRCm39 Ensembl1079,656,823 - 79,666,324 (+)Ensembl
GRCm381079,821,019 - 79,830,452 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1079,820,989 - 79,830,490 (+)EnsemblGRCm38mm10GRCm38
MGSCv371079,283,766 - 79,293,197 (+)NCBIGRCm37mm9NCBIm37
MGSCv361079,224,150 - 79,233,581 (+)NCBImm8
Celera1080,835,820 - 80,845,252 (+)NCBICelera
Cytogenetic Map10C1NCBI
Misp
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.279,870,390 - 9,886,541 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl79,870,444 - 9,886,541 (-)Ensembl
Rnor_6.0712,691,834 - 12,707,927 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl712,697,743 - 12,707,922 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0712,861,587 - 12,877,644 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4711,389,248 - 11,399,427 (-)NCBIRGSC3.4rn4RGSC3.4
Celera78,051,026 - 8,061,205 (-)NCBICelera
Cytogenetic Map7q11NCBI
Misp
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554957,032,876 - 7,038,916 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554957,034,664 - 7,044,886 (-)NCBIChiLan1.0ChiLan1.0
MISP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.119717,766 - 731,942 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl19717,766 - 731,942 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v019369,238 - 383,633 (-)NCBIMhudiblu_PPA_v0panPan3
MISP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12057,839,423 - 57,847,013 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2057,838,731 - 57,843,219 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2057,641,618 - 57,647,893 (-)NCBI
ROS_Cfam_1.02058,581,930 - 58,588,205 (-)NCBI
UMICH_Zoey_3.12057,636,448 - 57,642,628 (-)NCBI
UNSW_CanFamBas_1.02058,115,878 - 58,122,076 (-)NCBI
UU_Cfam_GSD_1.02058,319,170 - 58,325,443 (-)NCBI
LOC101970375
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118217,540,716 - 217,550,768 (-)NCBI
SpeTri2.0NW_004936588290,620 - 294,058 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC103233577
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.16505,841 - 520,758 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl6506,482 - 520,827 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660818,403,707 - 8,451,647 (-)NCBIVero_WHO_p1.0
Misp
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248287,800,424 - 7,812,035 (-)NCBIHetGla_female_1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system nervous system renal system reproductive system respiratory system
High
Medium 8
Low 3 1 3 2 1
Below cutoff 1 1 4 2 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000014669   ⟹   ENSSSCP00000014274
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl277,609,485 - 77,617,306 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000054607   ⟹   ENSSSCP00000044962
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl277,602,142 - 77,619,087 (-)Ensembl
RefSeq Acc Id: XM_021084291   ⟹   XP_020939950
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1277,607,185 - 77,619,124 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021084292   ⟹   XP_020939951
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1277,607,185 - 77,617,955 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_020939950 (Get FASTA)   NCBI Sequence Viewer  
  XP_020939951 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_020939950   ⟸   XM_021084291
- Sequence:
RefSeq Acc Id: XP_020939951   ⟸   XM_021084292
- Sequence:
RefSeq Acc Id: ENSSSCP00000044962   ⟸   ENSSSCT00000054607
RefSeq Acc Id: ENSSSCP00000014274   ⟸   ENSSSCT00000014669
Protein Domains
AKAP2_C


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000013425 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00070026823 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000014274 UniProtKB/TrEMBL
  ENSSSCP00000044962 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00070045608 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000014669 UniProtKB/TrEMBL
  ENSSSCT00000054607 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00070053797 UniProtKB/TrEMBL
InterPro AKAP2_C UniProtKB/TrEMBL
  MISP/MISP3 UniProtKB/TrEMBL
NCBI Gene MISP ENTREZGENE
PANTHER PTHR18839 UniProtKB/TrEMBL
Pfam AKAP2_C UniProtKB/TrEMBL
UniProt A0A287ALE7_PIG UniProtKB/TrEMBL
  A0A4X1VWG1_PIG UniProtKB/TrEMBL
  F1S6R3_PIG UniProtKB/TrEMBL
VGNC ID VGNC:90241 ENTREZGENE