DAPK3 (death associated protein kinase 3) - Rat Genome Database

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Gene: DAPK3 (death associated protein kinase 3) Sus scrofa
Analyze
Symbol: DAPK3
Name: death associated protein kinase 3
RGD ID: 14227131
Description: ENCODES a protein that exhibits DNA-binding transcription factor binding (ortholog); kinase activity (ortholog); protein kinase activity (ortholog); INVOLVED IN apoptotic signaling pathway (ortholog); neuron differentiation (ortholog); positive regulation of apoptotic process (ortholog); ASSOCIATED WITH amenorrhea (ortholog); RASopathy (ortholog); FOUND IN actin filament (ortholog); chromosome, centromeric region (ortholog); membrane raft (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: death-associated protein kinase 3; ZIPK
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl274,759,004 - 74,775,330 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1274,758,962 - 74,776,355 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2275,303,427 - 75,320,026 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
amenorrhea  (ISO)
RASopathy  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
DAPK3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl274,759,004 - 74,775,330 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1274,758,962 - 74,776,355 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2275,303,427 - 75,320,026 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DAPK3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38193,958,453 - 3,971,099 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl193,958,453 - 3,971,123 (-)EnsemblGRCh38hg38GRCh38
GRCh37193,958,451 - 3,971,097 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36193,909,452 - 3,920,826 (-)NCBINCBI36Build 36hg18NCBI36
Build 34193,909,451 - 3,920,826NCBI
Celera193,895,592 - 3,906,968 (-)NCBICelera
Cytogenetic Map19p13.3NCBI
HuRef193,721,681 - 3,733,014 (-)NCBIHuRef
CHM1_1193,958,113 - 3,969,502 (-)NCBICHM1_1
T2T-CHM13v2.0193,937,706 - 3,950,355 (-)NCBIT2T-CHM13v2.0
Dapk3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391081,018,821 - 81,029,031 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1081,018,839 - 81,029,031 (+)EnsemblGRCm39 Ensembl
GRCm381081,182,987 - 81,193,197 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1081,183,005 - 81,193,197 (+)EnsemblGRCm38mm10GRCm38
MGSCv371080,645,752 - 80,655,942 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361080,587,134 - 80,596,127 (+)NCBIMGSCv36mm8
Celera1082,203,364 - 82,213,553 (+)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1039.72NCBI
Dapk3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr879,174,903 - 9,183,272 (-)NCBIGRCr8
mRatBN7.278,524,182 - 8,532,552 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl78,524,183 - 8,532,558 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx711,409,265 - 11,417,634 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0713,284,751 - 13,293,120 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0711,151,188 - 11,159,566 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0711,392,436 - 11,400,855 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl711,392,437 - 11,400,805 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0711,559,842 - 11,568,242 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4710,007,997 - 10,016,365 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1710,007,996 - 10,016,365 (-)NCBI
Celera76,712,067 - 6,720,435 (-)NCBICelera
Cytogenetic Map7q11NCBI
Dapk3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554954,810,474 - 4,823,259 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554954,809,475 - 4,822,210 (+)NCBIChiLan1.0ChiLan1.0
DAPK3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2208,357,518 - 8,369,504 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1197,589,027 - 7,601,004 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0192,984,806 - 2,996,782 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1193,934,496 - 3,946,011 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl193,934,496 - 3,946,011 (-)Ensemblpanpan1.1panPan2
DAPK3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12055,590,199 - 55,603,883 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2055,590,223 - 55,602,682 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2055,315,718 - 55,329,927 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02056,250,289 - 56,264,535 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2056,250,314 - 56,263,999 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12055,306,274 - 55,320,466 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02055,788,043 - 55,802,254 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02055,986,748 - 56,000,993 (+)NCBIUU_Cfam_GSD_1.0
Dapk3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118215,576,995 - 215,590,047 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365882,244,708 - 2,257,779 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365882,246,142 - 2,257,733 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DAPK3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.163,713,179 - 3,729,223 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl63,712,170 - 3,727,929 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660814,517,737 - 4,535,148 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dapk3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248285,621,696 - 5,625,601 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248285,616,839 - 5,626,849 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in DAPK3
219 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 23 3 2 5 14 12 23 3 6 3

Sequence


Ensembl Acc Id: ENSSSCT00000050198   ⟹   ENSSSCP00000045328
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl274,759,035 - 74,775,333 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000067222   ⟹   ENSSSCP00000071357
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl274,759,004 - 74,775,330 (+)Ensembl
RefSeq Acc Id: XM_021084109   ⟹   XP_020939768
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1274,758,962 - 74,776,355 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_020939768 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein BAN13543 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSSCP00000071357
  ENSSSCP00000071357.1
  ENSSSCP00005038941.1
  ENSSSCP00040026432.1
  ENSSSCP00045020094.1
  ENSSSCP00065043102.1
GenBank Protein JAA74192 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_020939768   ⟸   XM_021084109
- UniProtKB: A0A5G2RIF1 (UniProtKB/TrEMBL),   A0A8D1EQ22 (UniProtKB/TrEMBL),   A0A8D1HLI4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000045328   ⟸   ENSSSCT00000050198
Ensembl Acc Id: ENSSSCP00000071357   ⟸   ENSSSCT00000067222
Protein Domains
Protein kinase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000032170 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005039351 UniProtKB/TrEMBL
  ENSSSCG00040046554 UniProtKB/TrEMBL
  ENSSSCG00045017032 UniProtKB/TrEMBL
  ENSSSCG00065071521 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000067222 ENTREZGENE
  ENSSSCT00000067222.2 UniProtKB/TrEMBL
  ENSSSCT00005062976.1 UniProtKB/TrEMBL
  ENSSSCT00040062690.1 UniProtKB/TrEMBL
  ENSSSCT00045029022.1 UniProtKB/TrEMBL
  ENSSSCT00065098281.1 UniProtKB/TrEMBL
Gene3D-CATH Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro DAPK3_STKc UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/TrEMBL
NCBI Gene DAPK3 ENTREZGENE
PANTHER DEATH-ASSOCIATED PROTEIN KINASE 3 UniProtKB/TrEMBL
  SERINE/THREONINE-PROTEIN KINASE 17 UniProtKB/TrEMBL
Pfam Pkinase UniProtKB/TrEMBL
PROSITE PROTEIN_KINASE_ATP UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/TrEMBL
SMART S_TKc UniProtKB/TrEMBL
Superfamily-SCOP SSF56112 UniProtKB/TrEMBL
UniProt A0A5G2RIF1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1EQ22 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1HLI4 ENTREZGENE, UniProtKB/TrEMBL
  M3V830_PIG UniProtKB/TrEMBL
UniProt Secondary A0A4X1VU09 UniProtKB/TrEMBL
VGNC ID VGNC:87158 ENTREZGENE