ACTA1 (actin alpha 1, skeletal muscle) - Rat Genome Database

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Gene: ACTA1 (actin alpha 1, skeletal muscle) Sus scrofa
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Symbol: ACTA1
Name: actin alpha 1, skeletal muscle
RGD ID: 14142359
Description: ENCODES a protein that exhibits ATP binding (inferred); INVOLVED IN cellular response to organonitrogen compound (ortholog); mesenchyme migration (ortholog); positive regulation of gene expression (ortholog); ASSOCIATED WITH Actin-Accumulation Myopathy (ortholog); congenital fiber-type disproportion (ortholog); congenital structural myopathy (ortholog); FOUND IN actin cytoskeleton (ortholog); actin filament (ortholog); cell body (ortholog)
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: ACTA; actin, alpha skeletal muscle; alpha actin 1; beta actin; skeletal alpha actin
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11460,412,651 - 60,415,687 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21465,236,192 - 65,239,197 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:8973342   PMID:10229356   PMID:14681463   PMID:17145712   PMID:22162634  


Genomics

Comparative Map Data
ACTA1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11460,412,651 - 60,415,687 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21465,236,192 - 65,239,197 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ACTA1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1229,431,245 - 229,434,098 (-)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl1229,430,365 - 229,434,104 (-)EnsemblGRCh38hg38GRCh38
GRCh381229,431,245 - 229,434,094 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371229,566,992 - 229,569,841 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361227,633,615 - 227,636,466 (-)NCBINCBI36hg18NCBI36
Build 341225,873,729 - 225,876,578NCBI
Celera1202,835,304 - 202,838,155 (-)NCBI
Cytogenetic Map1q42.13NCBI
HuRef1200,057,954 - 200,060,804 (-)NCBIHuRef
CHM1_11230,839,339 - 230,842,183 (-)NCBICHM1_1
Acta1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398124,618,497 - 124,621,514 (-)NCBIGRCm39mm39
GRCm39 Ensembl8124,618,508 - 124,621,490 (-)Ensembl
GRCm388123,891,758 - 123,894,775 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8123,891,769 - 123,894,751 (-)EnsemblGRCm38mm10GRCm38
MGSCv378126,415,667 - 126,418,636 (-)NCBIGRCm37mm9NCBIm37
MGSCv368126,777,857 - 126,780,826 (-)NCBImm8
Celera8128,158,816 - 128,161,785 (-)NCBICelera
Cytogenetic Map8E2NCBI
cM Map872.26NCBI
Acta1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21951,883,713 - 51,886,725 (-)NCBI
Rnor_6.0 Ensembl1956,674,074 - 56,677,084 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01956,674,072 - 56,677,084 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01967,389,899 - 67,392,911 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41954,081,496 - 54,084,508 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11954,086,370 - 54,089,389 (-)NCBI
Celera1951,258,256 - 51,261,324 (-)NCBICelera
Cytogenetic Map19q12NCBI
Acta1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554928,644,146 - 8,647,523 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554928,644,696 - 8,647,412 (+)NCBIChiLan1.0ChiLan1.0
ACTA1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11210,007,622 - 210,010,459 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1210,007,622 - 210,010,469 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01204,975,646 - 204,978,523 (-)NCBIMhudiblu_PPA_v0panPan3
ACTA1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.149,811,726 - 9,814,533 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl49,811,801 - 9,814,530 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha49,802,887 - 9,805,701 (+)NCBI
ROS_Cfam_1.049,842,369 - 9,845,196 (+)NCBI
UMICH_Zoey_3.149,846,012 - 9,848,831 (+)NCBI
UNSW_CanFamBas_1.049,960,597 - 9,963,412 (+)NCBI
UU_Cfam_GSD_1.0410,212,935 - 10,215,761 (+)NCBI
Acta1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934444,071,243 - 44,074,156 (+)NCBI
SpeTri2.0NW_00493648420,236,320 - 20,239,385 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ACTA1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12566,700,448 - 66,703,325 (-)NCBI
ChlSab1.1 Ensembl2566,700,369 - 66,714,891 (-)Ensembl
Acta1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462477519,650,923 - 19,653,707 (+)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system
High 2
Medium 2
Low 2 2 10 1
Below cutoff 1 1 3 13 1 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001167795 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005670976 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021071930 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021071931 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AEMK02000096 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF054837 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK344130 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK347115 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK347196 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK394681 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK394684 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK396462 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK399616 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CU468504 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GFLN01099923 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U16368 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: NM_001167795   ⟹   NP_001161267
RefSeq Status: VALIDATED
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11460,412,942 - 60,415,687 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005670976   ⟹   XP_005671033
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11460,412,651 - 60,415,679 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021071930   ⟹   XP_020927589
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11460,412,683 - 60,415,679 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021071931   ⟹   XP_020927590
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11460,412,920 - 60,415,679 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: XP_005671033   ⟸   XM_005670976
- Peptide Label: isoform X2
- UniProtKB: P68137 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_020927589   ⟸   XM_021071930
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_020927590   ⟸   XM_021071931
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: NP_001161267   ⟸   NM_001167795
- UniProtKB: P68137 (UniProtKB/Swiss-Prot)
- Sequence:


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000010190 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015047339 UniProtKB/Swiss-Prot
  ENSSSCG00040044916 UniProtKB/Swiss-Prot
  ENSSSCG00055024685 UniProtKB/Swiss-Prot
  ENSSSCG00065076746 UniProtKB/Swiss-Prot
  ENSSSCG00070014732 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000010867 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00000055172 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00000056701 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00015025920 UniProtKB/Swiss-Prot
  ENSSSCP00040026558 UniProtKB/Swiss-Prot
  ENSSSCP00055039593 UniProtKB/Swiss-Prot
  ENSSSCP00065047178 UniProtKB/Swiss-Prot
  ENSSSCP00070024117 UniProtKB/TrEMBL
  ENSSSCP00070024127 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000011156 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00000040776 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00000050871 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00015064766 UniProtKB/Swiss-Prot
  ENSSSCT00040062959 UniProtKB/Swiss-Prot
  ENSSSCT00055049539 UniProtKB/Swiss-Prot
  ENSSSCT00065106117 UniProtKB/Swiss-Prot
  ENSSSCT00070028930 UniProtKB/TrEMBL
  ENSSSCT00070028942 UniProtKB/TrEMBL
InterPro Actin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Actin/actin-like_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Actin_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ATPase_NBD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report ssc:100154254 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene ACTA1 ENTREZGENE
PANTHER PTHR11937 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Actin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS ACTIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE ACTINS_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ACTINS_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ACTINS_ACT_LIKE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART ACTIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF53067 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A287BF33_PIG UniProtKB/TrEMBL
  A0A480QNI6_PIG UniProtKB/TrEMBL
  A0A4X1U349_PIG UniProtKB/TrEMBL
  A0A4X1U7L3_PIG UniProtKB/TrEMBL
  A0A5S6G831_PIG UniProtKB/TrEMBL
  A0A5S6IE01_PIG UniProtKB/TrEMBL
  ACTS_PIG UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary P02568 UniProtKB/Swiss-Prot
  P99020 UniProtKB/Swiss-Prot