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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of bicellular tight junction assembly
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Accession:GO:2000810 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of tight junction assembly.
Synonyms:exact_synonym: regulation of tight junction formation
 xref: Reactome:R-HSA-8935964 "RUNX1 regulates expression of components of tight junctions"


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regulation of bicellular tight junction assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F11r F11 receptor involved_in ISO (PMID:25753039) RGD PMID:25753039 NCBI chr13:83,873,797...83,897,388
Ensembl chr13:83,873,797...83,897,402 		JBrowse link
G Fzd5 frizzled class receptor 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3583769 (PMID:23610556)		 Ensembl
RGD		 PMID:23610556 GO_REF:0000107 NCBI chr 9:66,113,096...66,120,276
Ensembl chr 9:66,113,112...66,121,457 		JBrowse link
G Gja1 gap junction protein, alpha 1 IMP RGD PMID:19509333 RGD:6784505 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582 		JBrowse link
G Gpbar1 G protein-coupled bile acid receptor 1 involved_in ISO (PMID:22046243) RGD PMID:22046243 NCBI chr 9:75,860,758...75,863,260
Ensembl chr 9:75,860,677...75,863,168 		JBrowse link
G Myo1c myosin 1C involved_in ISO
IEA		 (PMID:21402783)
GO_REF:0000107		 RGD
Ensembl		 PMID:21402783 GO_REF:0000107 NCBI chr10:60,498,372...60,520,752
Ensembl chr10:60,498,280...60,520,752 		JBrowse link
G Nedd4l NEDD4 like E3 ubiquitin protein ligase acts_upstream_of_or_within ISO (PMID:20504882) RGD PMID:20504882 NCBI chr18:58,393,759...58,726,709
Ensembl chr18:58,393,509...58,723,137 		JBrowse link
G Pkp2 plakophilin 2 IMP RGD PMID:19509333 RGD:6784505 NCBI chr11:84,661,783...84,727,730
Ensembl chr11:84,661,783...84,727,730 		JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha involved_in ISO
IEA		 (PMID:15905176)
GO_REF:0000107		 RGD
Ensembl		 PMID:15905176 GO_REF:0000107 NCBI chr19:24,155,081...24,178,430
Ensembl chr19:24,155,090...24,178,430 		JBrowse link
G Prkch protein kinase C, eta involved_in ISO
ISS		 (PMID:19114660)
GO_REF:0000024		 RGD
UniProt		 PMID:19114660 GO_REF:0000024 NCBI chr 6:92,292,000...92,490,663
Ensembl chr 6:92,292,000...92,490,654 		JBrowse link
G Snai1 snail family transcriptional repressor 1 involved_in ISO (PMID:15314165) RGD PMID:15314165 NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969 		JBrowse link
G Snai2 snail family transcriptional repressor 2 involved_in ISO (PMID:15314165) RGD PMID:15314165 NCBI chr11:86,182,788...86,186,203
Ensembl chr11:86,181,909...86,186,200 		JBrowse link
G Tjp1 tight junction protein 1 involved_in ISO (PMID:25753039) RGD PMID:25753039 NCBI chr 1:118,849,838...119,094,492
Ensembl chr 1:118,849,838...119,094,432 		JBrowse link
negative regulation of bicellular tight junction assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta involved_in ISO
IEA		 (PMID:25816133)
GO_REF:0000107		 RGD
Ensembl		 PMID:25816133 GO_REF:0000107 NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250 		JBrowse link
G Mir105 microRNA 105 acts_upstream_of ISO (PMID:24735924) RGD PMID:24735924 NCBI chr  X:150,438,529...150,438,601
Ensembl chr  X:150,438,529...150,438,601 		JBrowse link
G Mir142 microRNA 142 involved_in ISO (PMID:27277258) RGD PMID:27277258 NCBI chr10:72,557,864...72,557,950
Ensembl chr10:72,557,857...72,557,967 		JBrowse link
G Rock1 Rho-associated coiled-coil containing protein kinase 1 involved_in IEA
ISO		 GO_REF:0000107
UniProtKB:O75116 (PMID:25816133)		 Ensembl
RGD		 PMID:25816133 GO_REF:0000107 NCBI chr18:1,114,532...1,236,345
Ensembl chr18:1,115,905...1,235,571 		JBrowse link
G Rock2 Rho-associated coiled-coil containing protein kinase 2 involved_in IEA
ISO		 GO_REF:0000107
UniProtKB:Q13464 (PMID:25816133)		 Ensembl
RGD		 PMID:25816133 GO_REF:0000107 NCBI chr 6:39,679,116...39,774,033
Ensembl chr 6:39,679,082...39,774,031 		JBrowse link
G Rps6 ribosomal protein S6 IDA RGD PMID:25217631 RGD:11041641 NCBI chr 5:101,371,716...101,374,576
Ensembl chr 5:101,371,136...101,374,602
Ensembl chr 5:101,371,136...101,374,602 		JBrowse link
G Tnf tumor necrosis factor involved_in ISO (PMID:25816133) RGD PMID:25816133 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
positive regulation of bicellular tight junction assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvrl1 activin A receptor like type 1 involved_in ISO UniProtKB:Q9UK05 (PMID:32561494) RGD PMID:32561494 NCBI chr 7:132,239,200...132,256,592
Ensembl chr 7:132,239,729...132,256,591 		JBrowse link
G Cdc45 cell division cycle 45 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr11:82,185,427...82,210,630
Ensembl chr11:82,185,473...82,210,619 		JBrowse link
G Cldn1 claudin 1 IMP RGD PMID:22684624 RGD:11341733 NCBI chr11:74,421,569...74,436,728
Ensembl chr11:74,421,569...74,436,724 		JBrowse link
G Cldn5 claudin 5 involved_in ISO (PMID:25323998) RGD PMID:25323998 NCBI chr11:82,212,822...82,214,248
Ensembl chr11:82,211,475...82,214,992 		JBrowse link
G Dsg3 desmoglein 3 involved_in ISO (PMID:22796473) RGD PMID:22796473 NCBI chr18:11,799,355...11,830,988
Ensembl chr18:11,798,900...11,830,818 		JBrowse link
G Epha2 Eph receptor A2 involved_in ISO (PMID:27815408) RGD PMID:27815408 NCBI chr 5:153,605,644...153,634,115
Ensembl chr 5:153,605,644...153,634,117 		JBrowse link
G Gcg glucagon involved_in ISO (PMID:25050009) RGD PMID:25050009 NCBI chr 3:47,113,914...47,122,958
Ensembl chr 3:47,113,914...47,122,929 		JBrowse link
G Gdf2 growth differentiation factor 2 involved_in ISO (PMID:32561494) RGD PMID:32561494 NCBI chr16:9,255,430...9,261,429
Ensembl chr16:9,255,430...9,261,429 		JBrowse link
G Il17a interleukin 17A involved_in IEA
ISO		 GO_REF:0000107
(PMID:26431948)		 Ensembl
RGD		 PMID:26431948 GO_REF:0000107 NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889 		JBrowse link
G Nphp1 nephrocystin 1 involved_in ISO (PMID:19755384) RGD PMID:19755384 NCBI chr 3:114,960,650...115,016,234
Ensembl chr 3:114,960,650...115,016,234 		JBrowse link
G Nphp4 nephrocystin 4 involved_in ISO (PMID:19755384) RGD PMID:19755384 NCBI chr 5:162,986,157...163,073,708
Ensembl chr 5:162,988,370...163,073,706 		JBrowse link
G Rac1 Rac family small GTPase 1 involved_in ISO
ISS
IEA		 (PMID:22796473)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:22796473 GO_REF:0000024 GO_REF:0000107 NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20536
    regulation of biological process 13374
      regulation of cellular process 13012
        regulation of cellular component organization 2711
          regulation of cell junction assembly 321
            regulation of bicellular tight junction assembly 31
              negative regulation of bicellular tight junction assembly 7
              positive regulation of bicellular tight junction assembly 12
Path 2
Term Annotations click to browse term
  biological_process 20536
    cellular process 19526
      cellular component organization or biogenesis 7187
        cellular component organization 6903
          cellular component assembly 3197
            cell junction assembly 573
              cell-cell junction assembly 174
                apical junction assembly 104
                  bicellular tight junction assembly 95
                    regulation of bicellular tight junction assembly 31
                      negative regulation of bicellular tight junction assembly 7
                      positive regulation of bicellular tight junction assembly 12
paths to the root