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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of autophagy of mitochondrion
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Accession:GO:1903599 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of mitochondrion degradation by autophagy.
Comment:An example of this AMBRA1 - human (Q9C0C7) in PMID:21753002 inferred from direct assay
Synonyms:exact_synonym: up regulation of mitochondrion degradation;   up regulation of mitophagy;   upregulation of mitochondrion degradation;   upregulation of mitophagy
 narrow_synonym: activation of mitophagy
 broad_synonym: positive regulation of mitochondrial degradation
 related_synonym: activation of mitochondrion degradation


show annotations for term's descendants           Sort by:
positive regulation of autophagy of mitochondrion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bnip3 BCL2 interacting protein 3 IMP RGD PMID:23698117 RGD:11561968 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359 		JBrowse link
G Fbxo7 F-box protein 7 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:17,809,224...17,837,549
Ensembl chr 7:17,809,231...17,837,530 		JBrowse link
positive regulation of mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ambra1 autophagy and beclin 1 regulator 1 involved_in ISO (PMID:30217973) RGD PMID:30217973 NCBI chr 3:77,700,936...77,890,221
Ensembl chr 3:77,700,936...77,890,221 		JBrowse link
G Atg7 autophagy related 7 IMP RGD PMID:37042059 RGD:407532700 NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593 		JBrowse link
G Cers1 ceramide synthase 1 involved_in ISO (PMID:22922758) RGD PMID:22922758 NCBI chr16:19,097,309...19,112,519
Ensembl chr16:19,104,466...19,112,519 		JBrowse link
G Dele1 DAP3 binding cell death enhancer 1 involved_in ISO (PMID:38340717) RGD PMID:38340717 NCBI chr18:30,085,093...30,098,105
Ensembl chr18:30,085,126...30,098,756 		JBrowse link
G Eif2ak1 eukaryotic translation initiation factor 2 alpha kinase 1 involved_in ISO
IEA
ISS		 (PMID:38340717)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:38340717 GO_REF:0000024 GO_REF:0000107 NCBI chr12:10,710,771...10,744,597
Ensembl chr12:10,705,874...10,744,573 		JBrowse link
G Fbxo7 F-box protein 7 involved_in IMP
ISO		 PMID:26310625
(PMID:26310625)		 RGD PMID:26310625 PMID:26310625 RGD:11536096 NCBI chr 7:17,809,224...17,837,549
Ensembl chr 7:17,809,231...17,837,530 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
G Htt huntingtin involved_in IEA
ISO		 GO_REF:0000107
(PMID:25686248)		 Ensembl
RGD		 PMID:25686248 GO_REF:0000107 NCBI chr14:75,845,836...75,996,094
Ensembl chr14:75,845,836...75,995,070 		JBrowse link
G Irgm immunity-related GTPase M involved_in ISS
ISO		 GO_REF:0000024
(PMID:33510463)
(PMID:21102437)
(PMID:32939830)		 UniProt
RGD		 PMID:21102437 PMID:32939830 PMID:33510463 GO_REF:0000024 NCBI chr10:33,233,513...33,241,594
Ensembl chr10:33,233,455...33,241,578 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 involved_in ISO (PMID:31919280) RGD PMID:31919280 NCBI chr19:18,382,369...18,422,817
Ensembl chr19:18,382,439...18,417,177 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in IMP
ISO		 (PMID:26310625) RGD PMID:26310625 PMID:28608965 RGD:13432560 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Slc25a4 solute carrier family 25 member 4 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:31618756)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:31618756 GO_REF:0000024 GO_REF:0000107 NCBI chr16:46,072,935...46,076,730
Ensembl chr16:46,072,939...46,076,733 		JBrowse link
G Slc25a5 solute carrier family 25 member 5 involved_in ISS
ISO		 GO_REF:0000024
(PMID:31618756)		 UniProt
RGD		 PMID:31618756 GO_REF:0000024 NCBI chr  X:116,031,896...116,034,963
Ensembl chr  X:116,031,803...116,034,967 		JBrowse link
G Stub1 STIP1 homology and U-box containing protein 1 involved_in IMP PMID:29934347 UniProt PMID:29934347 RGD:405650300 NCBI chr10:14,850,765...14,853,046
Ensembl chr10:14,850,765...14,853,046 		JBrowse link
G Ube2a ubiquitin-conjugating enzyme E2A involved_in ISO (PMID:23685073) RGD PMID:23685073 NCBI chr  X:116,114,339...116,125,076
Ensembl chr  X:116,113,875...116,125,070 		JBrowse link
G Vps13d vacuolar protein sorting 13 homolog D involved_in ISO (PMID:29307555) RGD PMID:29307555 NCBI chr 5:156,830,509...157,055,895
Ensembl chr 5:156,830,512...157,055,891 		JBrowse link
positive regulation of type 2 mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp5if1 ATP synthase inhibitory factor subunit 1 involved_in ISO (PMID:24005319) RGD PMID:24005319 NCBI chr 5:144,738,950...144,742,668
Ensembl chr 5:144,738,950...144,742,668 		JBrowse link
G Cdc37 cell division cycle 37, HSP90 cochaperone involved_in ISO
IEA		 (PMID:21855797)
GO_REF:0000107		 RGD
Ensembl		 PMID:21855797 GO_REF:0000107 NCBI chr 8:19,677,400...19,690,761
Ensembl chr 8:19,671,938...19,690,809 		JBrowse link
G Gba1 glucosylceramidase beta 1 acts_upstream_of_or_within ISO (PMID:23707074) RGD PMID:23707074 NCBI chr 2:174,609,437...174,615,457
Ensembl chr 2:174,609,403...174,618,263 		JBrowse link
G Hdac6 histone deacetylase 6 involved_in ISO UniProtKB:Q9JK66 (PMID:20457763) RGD PMID:20457763 NCBI chr  X:14,550,645...14,572,445
Ensembl chr  X:14,551,044...14,572,441 		JBrowse link
G Hk2 hexokinase 2 involved_in ISO (PMID:23962723) RGD PMID:23962723 NCBI chr 4:115,234,509...115,283,530
Ensembl chr 4:115,234,509...115,283,530 		JBrowse link
G Huwe1 HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1 involved_in ISO (PMID:30217973) RGD PMID:30217973 NCBI chr  X:20,873,795...21,001,378
Ensembl chr  X:20,873,795...21,001,262 		JBrowse link
G Mul1 mitochondrial E3 ubiquitin protein ligase 1 involved_in ISO (PMID:24709290) RGD PMID:24709290 NCBI chr 5:150,652,812...150,661,863
Ensembl chr 5:150,652,812...150,661,863 		JBrowse link
G Pink1 PTEN induced kinase 1 involved_in ISO (PMID:20871098) RGD PMID:20871098 NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO
IEA		 (PMID:20457763), (PMID:20871098), (PMID:23212910)
GO_REF:0000107		 RGD
Ensembl		 PMID:20457763 PMID:20871098 PMID:23212910 GO_REF:0000107 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Tomm7 translocase of outer mitochondrial membrane 7 involved_in ISO (PMID:24270810) RGD PMID:24270810 NCBI chr 4:11,305,122...11,311,963
Ensembl chr 4:11,305,110...11,311,962 		JBrowse link
G Vdac1 voltage-dependent anion channel 1 involved_in ISO (PMID:32047033) RGD PMID:32047033 NCBI chr10:36,532,306...36,559,642
Ensembl chr10:36,532,244...36,559,640 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20069
    cellular process 19150
      process utilizing autophagic mechanism 560
        autophagy 560
          positive regulation of autophagy 172
            positive regulation of autophagy of mitochondrion 27
              positive regulation of mitophagy + 26
Path 2
Term Annotations click to browse term
  biological_process 20069
    biological regulation 13554
      regulation of biological process 13131
        regulation of cellular process 12768
          regulation of metabolic process 6743
            regulation of catabolic process 1110
              regulation of autophagy 318
                regulation of autophagy of mitochondrion 48
                  positive regulation of autophagy of mitochondrion 27
                    positive regulation of mitophagy + 26
paths to the root