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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of autophagy of mitochondrion
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Accession:GO:1903146 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of mitochondrion degradation by an autophagic process.
Synonyms:broad_synonym: regulation of mitochondrion degradation



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regulation of autophagy of mitochondrion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bnip3l BCL2 interacting protein 3 like involved_in ISO UniProtKB:Q9Z2F7 (MGI:5616312|PMID:20200478) RGD PMID:20200478 MGI:5616312 NCBI chr15:41,174,594...41,197,730
Ensembl chr15:41,174,594...41,197,803
JBrowse link
G Csnk2a2 casein kinase 2 alpha 2 involved_in ISO (PMID:24912190) ParkinsonsUK-UCL PMID:24912190 NCBI chr19:9,556,443...9,596,080
Ensembl chr19:9,556,260...9,596,080
JBrowse link
G Cttn cortactin involved_in ISO
IEA
(MGI:5616310|PMID:20457763)
GO_REF:0000107
RGD
Ensembl
PMID:20457763 GO_REF:0000107 MGI:5616310 NCBI chr 1:199,599,710...199,635,254
Ensembl chr 1:199,599,710...199,635,164
JBrowse link
G Dnm1l dynamin 1-like involved_in ISO UniProtKB:Q9BXM7 (PMID:19279012) RGD PMID:19279012 NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482
JBrowse link
G Fbxw7 F-box and WD repeat domain containing 7 involved_in ISO (PMID:24912190) RGD PMID:24912190 NCBI chr 2:170,150,552...170,310,698
Ensembl chr 2:170,149,694...170,309,941
JBrowse link
G Fzd5 frizzled class receptor 5 involved_in ISO (PMID:24912190) ParkinsonsUK-UCL PMID:24912190 NCBI chr 9:66,117,370...66,119,127
Ensembl chr 9:66,113,112...66,121,457
JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha involved_in ISO (PMID:24912190) RGD PMID:24912190 NCBI chr 1:80,815,843...80,825,732
Ensembl chr 1:80,815,850...80,825,802
JBrowse link
G Parl presenilin associated, rhomboid-like involved_in ISO (MGI:5619462|PMID:21355049) RGD PMID:21355049 MGI:5619462 NCBI chr11:80,594,059...80,620,506
Ensembl chr11:80,593,192...80,620,506
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 involved_in ISO (PMID:24912190) RGD PMID:24912190 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 involved_in ISO (PMID:24912190) ParkinsonsUK-UCL PMID:24912190 NCBI chr 7:113,663,202...113,720,850
Ensembl chr 7:113,663,202...113,720,848
JBrowse link
G Usp36 ubiquitin specific peptidase 36 involved_in ISO (PMID:24912190) ParkinsonsUK-UCL PMID:24912190 NCBI chr10:103,497,349...103,528,877
Ensembl chr10:103,497,349...103,528,877
JBrowse link
G Vdac1 voltage-dependent anion channel 1 involved_in ISO (MGI:5689082|PMID:25470454) RGD PMID:25470454 MGI:5689082 NCBI chr10:36,532,306...36,559,642
Ensembl chr10:36,532,244...36,559,640
JBrowse link
negative regulation of autophagy of mitochondrion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pink1 PTEN induced kinase 1 involved_in ISO (PMID:19279012) RGD PMID:19279012 NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635
JBrowse link
G Tspo translocator protein involved_in ISO (PMID:25470454)
(MGI:5689082|PMID:25470454)
RGD PMID:25470454 MGI:5689082 NCBI chr 7:114,720,188...114,730,450
Ensembl chr 7:114,720,188...114,730,450
JBrowse link
negative regulation of mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clec16a C-type lectin domain containing 16A acts_upstream_of_or_within ISO MGI:5648633 (MGI:5603233|PMID:24949970) RGD PMID:24949970 MGI:5603233 NCBI chr10:4,927,804...5,123,749
Ensembl chr10:4,928,030...5,123,578
JBrowse link
G Pink1 PTEN induced kinase 1 involved_in ISO (PMID:19279012) RGD PMID:19279012 NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635
JBrowse link
G Rnf41 ring finger protein 41 acts_upstream_of_or_within ISO MGI:1921624 (MGI:5603233|PMID:24949970) RGD PMID:24949970 MGI:5603233 NCBI chr 7:838,160...876,869
Ensembl chr 7:838,203...865,511
JBrowse link
G Tigar TP53 induced glycolysis regulatory phosphatase acts_upstream_of_or_within ISO MGI:5319187 (MGI:5319065|PMID:22044588) RGD PMID:22044588 MGI:5319065 NCBI chr 4:159,927,138...159,946,094
Ensembl chr 4:159,927,139...159,946,029
JBrowse link
G Tp53 tumor protein p53 acts_upstream_of_or_within ISO MGI:1857263 (MGI:5319065|PMID:22044588) RGD PMID:22044588 MGI:5319065 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Usp30 ubiquitin specific peptidase 30 IMP RGD PMID:24896179 RGD:13208875 NCBI chr12:42,501,345...42,555,311
Ensembl chr12:42,501,348...42,555,616
JBrowse link
negative regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Vps13c vacuolar protein sorting 13 homolog C involved_in ISO
ISS
(PMID:26942284)
GO_REF:0000024
RGD
ParkinsonsUK-UCL
PMID:26942284 GO_REF:0000024 NCBI chr 8:68,478,366...68,651,893
Ensembl chr 8:68,478,395...68,651,895
JBrowse link
positive regulation of autophagy of mitochondrion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bnip3 BCL2 interacting protein 3 IMP RGD PMID:23698117 RGD:11561968 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359
JBrowse link
G Fbxo7 F-box protein 7 involved_in IBA
IMP
ISO
PMID:21873635
PMID:26310625
(PMID:26310625)
RGD PMID:26310625 PMID:21873635 PMID:26310625 RGD:13792537, RGD:11536096 NCBI chr 7:17,809,224...17,837,549
Ensembl chr 7:17,809,231...17,837,530
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha involved_in IEA
ISO
GO_REF:0000107
(MGI:3796473|PMID:18281291)
Ensembl
RGD
PMID:18281291 GO_REF:0000107 MGI:3796473 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Htt huntingtin involved_in IEA
ISO
GO_REF:0000107
(PMID:25686248)
Ensembl
RGD
PMID:25686248 GO_REF:0000107 NCBI chr14:75,845,836...75,996,094
Ensembl chr14:75,845,836...75,995,070
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO (PMID:26310625) RGD PMID:26310625 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555
JBrowse link
positive regulation of mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ambra1 autophagy and beclin 1 regulator 1 involved_in ISO (PMID:30217973) RGD PMID:30217973 NCBI chr 3:77,700,936...77,890,221
Ensembl chr 3:77,700,936...77,890,221
JBrowse link
G Cers1 ceramide synthase 1 involved_in ISO (PMID:22922758) RGD PMID:22922758 NCBI chr16:19,097,309...19,112,519
Ensembl chr16:19,104,466...19,112,519
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase IMP RGD PMID:28608965 RGD:13432560 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555
JBrowse link
G Slc25a4 solute carrier family 25 member 4 involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:6407583|PMID:31618756)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:31618756 GO_REF:0000024 GO_REF:0000107 MGI:6407583 NCBI chr16:46,072,935...46,076,730
Ensembl chr16:46,072,939...46,076,733
JBrowse link
G Slc25a5 solute carrier family 25 member 5 involved_in ISS
ISO
GO_REF:0000024
(MGI:6407583|PMID:31618756)
UniProt
RGD
PMID:31618756 GO_REF:0000024 MGI:6407583 NCBI chr  X:116,031,896...116,034,963
Ensembl chr  X:116,031,803...116,034,967
JBrowse link
G Vdac1 voltage-dependent anion channel 1 involved_in ISO (PMID:32047033) RGD PMID:32047033 NCBI chr10:36,532,306...36,559,642
Ensembl chr10:36,532,244...36,559,640
JBrowse link
G Vps13d vacuolar protein sorting 13 homolog D involved_in ISO (PMID:29307555) RGD PMID:29307555 NCBI chr 5:156,830,509...157,055,895
Ensembl chr 5:156,830,512...157,055,891
JBrowse link
positive regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Vdac1 voltage-dependent anion channel 1 involved_in ISO (PMID:32047033) RGD PMID:32047033 NCBI chr10:36,532,306...36,559,642
Ensembl chr10:36,532,244...36,559,640
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18734
    cellular process 17431
      process utilizing autophagic mechanism 484
        autophagy 484
          autophagy of mitochondrion 91
            regulation of autophagy of mitochondrion 30
              negative regulation of autophagy of mitochondrion + 7
              positive regulation of autophagy of mitochondrion + 11
              regulation of mitophagy + 14
Path 2
Term Annotations click to browse term
  biological_process 18734
    cellular process 17431
      cellular component organization or biogenesis 6532
        cellular component organization 6307
          organelle organization 3900
            mitochondrion organization 576
              mitochondrion disassembly 91
                autophagy of mitochondrion 91
                  regulation of autophagy of mitochondrion 30
                    negative regulation of autophagy of mitochondrion + 7
                    positive regulation of autophagy of mitochondrion + 11
                    regulation of mitophagy + 14
paths to the root