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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of autophagy of mitochondrion
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Accession:GO:1903146 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of mitochondrion degradation by an autophagic process.
Synonyms:broad_synonym: regulation of mitochondrion degradation



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negative regulation of mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clec16a C-type lectin domain containing 16A acts_upstream_of_or_within ISO MGI:5648633 (PMID:24949970) RGD PMID:24949970 NCBI chr10:4,927,799...5,123,749
Ensembl chr10:4,928,030...5,123,578
JBrowse link
G Pink1 PTEN induced kinase 1 involved_in ISO (PMID:19279012) RGD PMID:19279012 NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635
JBrowse link
G Rnf41 ring finger protein 41 acts_upstream_of_or_within ISO MGI:1921624 (PMID:24949970) RGD PMID:24949970 NCBI chr 7:838,160...876,869
Ensembl chr 7:838,203...865,511
JBrowse link
G Tigar TP53 induced glycolysis regulatory phosphatase acts_upstream_of_or_within ISO MGI:5319187 (PMID:22044588) RGD PMID:22044588 NCBI chr 4:159,927,136...159,946,077
Ensembl chr 4:159,927,139...159,946,029
Ensembl chr 6:159,927,139...159,946,029
JBrowse link
G Tp53 tumor protein p53 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1857263 (PMID:22044588)
Ensembl
RGD
PMID:22044588 GO_REF:0000107 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tspo translocator protein involved_in ISO (PMID:25470454) RGD PMID:25470454 NCBI chr 7:114,720,188...114,730,450
Ensembl chr 7:114,720,188...114,730,450
JBrowse link
G Usp30 ubiquitin specific peptidase 30 IMP RGD PMID:24896179 RGD:13208875 NCBI chr12:42,501,345...42,555,311
Ensembl chr12:42,501,348...42,555,616
JBrowse link
negative regulation of type 2 mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Htra2 HtrA serine peptidase 2 involved_in ISO (PMID:24709290) RGD PMID:24709290 NCBI chr 4:115,556,914...115,560,202
Ensembl chr 4:115,556,916...115,560,095
JBrowse link
G Vps13c vacuolar protein sorting 13 homolog C involved_in ISO
ISS
(PMID:26942284)
GO_REF:0000024
RGD
ParkinsonsUK-UCL
PMID:26942284 GO_REF:0000024 NCBI chr 8:68,478,366...68,651,893
Ensembl chr 8:68,478,395...68,651,895
JBrowse link
positive regulation of autophagy of mitochondrion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bnip3 BCL2 interacting protein 3 IMP RGD PMID:23698117 RGD:11561968 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359
JBrowse link
G Fbxo7 F-box protein 7 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:17,809,224...17,837,549
Ensembl chr 7:17,809,231...17,837,530
JBrowse link
positive regulation of mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ambra1 autophagy and beclin 1 regulator 1 involved_in ISO (PMID:30217973) RGD PMID:30217973 NCBI chr 3:77,700,936...77,890,221
Ensembl chr 3:77,700,936...77,890,221
JBrowse link
G Atg7 autophagy related 7 IMP RGD PMID:37042059 RGD:407532700 NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593
JBrowse link
G Cers1 ceramide synthase 1 involved_in ISO (PMID:22922758) RGD PMID:22922758 NCBI chr16:19,097,309...19,112,519
Ensembl chr16:19,104,466...19,112,519
JBrowse link
G Dele1 DAP3 binding cell death enhancer 1 involved_in ISO (PMID:38340717) RGD PMID:38340717 NCBI chr18:30,085,093...30,098,105
Ensembl chr18:30,085,126...30,098,756
JBrowse link
G Eif2ak1 eukaryotic translation initiation factor 2 alpha kinase 1 involved_in ISO
IEA
ISS
(PMID:38340717)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:38340717 GO_REF:0000024 GO_REF:0000107 NCBI chr12:10,710,771...10,744,597
Ensembl chr12:10,705,874...10,744,573
JBrowse link
G Fbxo7 F-box protein 7 involved_in IMP
ISO
PMID:26310625
(PMID:26310625)
RGD PMID:26310625 PMID:26310625 RGD:11536096 NCBI chr 7:17,809,224...17,837,549
Ensembl chr 7:17,809,231...17,837,530
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Htt huntingtin involved_in IEA
ISO
GO_REF:0000107
(PMID:25686248)
Ensembl
RGD
PMID:25686248 GO_REF:0000107 NCBI chr14:75,845,836...75,996,094
Ensembl chr14:75,845,836...75,995,070
JBrowse link
G Irgm immunity-related GTPase M involved_in ISS
ISO
GO_REF:0000024
(PMID:33510463)
(PMID:21102437)
(PMID:32939830)
UniProt
RGD
PMID:21102437 PMID:32939830 PMID:33510463 GO_REF:0000024 NCBI chr10:33,233,513...33,241,594
Ensembl chr10:33,233,455...33,241,578
JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 involved_in ISO (PMID:31919280) RGD PMID:31919280 NCBI chr19:18,382,369...18,422,817
Ensembl chr19:18,382,439...18,417,177
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in IMP
ISO
(PMID:26310625) RGD PMID:26310625 PMID:28608965 RGD:13432560 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555
JBrowse link
G Slc25a4 solute carrier family 25 member 4 involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:31618756)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:31618756 GO_REF:0000024 GO_REF:0000107 NCBI chr16:46,072,935...46,076,730
Ensembl chr16:46,072,939...46,076,733
JBrowse link
G Slc25a5 solute carrier family 25 member 5 involved_in ISS
ISO
GO_REF:0000024
(PMID:31618756)
UniProt
RGD
PMID:31618756 GO_REF:0000024 NCBI chr  X:116,031,896...116,034,963
Ensembl chr  X:116,031,803...116,034,967
JBrowse link
G Stub1 STIP1 homology and U-box containing protein 1 involved_in IMP PMID:29934347 UniProt PMID:29934347 RGD:405650300 NCBI chr10:14,850,765...14,853,046
Ensembl chr10:14,850,765...14,853,046
JBrowse link
G Ube2a ubiquitin-conjugating enzyme E2A involved_in ISO (PMID:23685073) RGD PMID:23685073 NCBI chr  X:116,114,339...116,125,076
Ensembl chr  X:116,113,875...116,125,070
JBrowse link
G Vps13d vacuolar protein sorting 13 homolog D involved_in ISO (PMID:29307555) RGD PMID:29307555 NCBI chr 5:156,830,509...157,055,895
Ensembl chr 5:156,830,512...157,055,891
JBrowse link
positive regulation of type 2 mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp5if1 ATP synthase inhibitory factor subunit 1 involved_in ISO (PMID:24005319) RGD PMID:24005319 NCBI chr 5:144,738,950...144,742,668
Ensembl chr 5:144,738,950...144,742,668
JBrowse link
G Cdc37 cell division cycle 37, HSP90 cochaperone involved_in ISO
IEA
(PMID:21855797)
GO_REF:0000107
RGD
Ensembl
PMID:21855797 GO_REF:0000107 NCBI chr 8:19,677,400...19,690,761
Ensembl chr 8:19,671,938...19,690,809
JBrowse link
G Gba1 glucosylceramidase beta 1 acts_upstream_of_or_within ISO (PMID:23707074) RGD PMID:23707074 NCBI chr 2:174,609,437...174,615,457
Ensembl chr 2:174,609,403...174,618,263
JBrowse link
G Hdac6 histone deacetylase 6 involved_in ISO UniProtKB:Q9JK66 (PMID:20457763) RGD PMID:20457763 NCBI chr  X:14,550,645...14,572,445
Ensembl chr  X:14,551,044...14,572,441
JBrowse link
G Hk2 hexokinase 2 involved_in ISO (PMID:23962723) RGD PMID:23962723 NCBI chr 4:115,234,509...115,283,530
Ensembl chr 4:115,234,509...115,283,530
JBrowse link
G Huwe1 HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1 involved_in ISO (PMID:30217973) RGD PMID:30217973 NCBI chr  X:20,873,795...21,001,378
Ensembl chr  X:20,873,795...21,001,262
JBrowse link
G Mul1 mitochondrial E3 ubiquitin protein ligase 1 involved_in ISO (PMID:24709290) RGD PMID:24709290 NCBI chr 5:150,652,812...150,661,863
Ensembl chr 5:150,652,812...150,661,863
JBrowse link
G Pink1 PTEN induced kinase 1 involved_in ISO (PMID:20871098) RGD PMID:20871098 NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO
IEA
(PMID:20457763), (PMID:20871098), (PMID:23212910)
GO_REF:0000107
RGD
Ensembl
PMID:20457763 PMID:20871098 PMID:23212910 GO_REF:0000107 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555
JBrowse link
G Tomm7 translocase of outer mitochondrial membrane 7 involved_in ISO (PMID:24270810) RGD PMID:24270810 NCBI chr 4:11,305,122...11,311,963
Ensembl chr 4:11,305,110...11,311,962
JBrowse link
G Vdac1 voltage-dependent anion channel 1 involved_in ISO (PMID:32047033) RGD PMID:32047033 NCBI chr10:36,532,306...36,559,642
Ensembl chr10:36,532,244...36,559,640
JBrowse link
regulation of mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy10 adenylate cyclase 10 IMP RGD PMID:31172217 RGD:329403053 NCBI chr13:77,747,752...77,833,952
Ensembl chr13:77,768,468...77,833,951
JBrowse link
G Bnip3l BCL2 interacting protein 3 like involved_in ISO UniProtKB:Q9Z2F7 (PMID:20200478) RGD PMID:20200478 NCBI chr15:41,174,594...41,197,730
Ensembl chr15:41,174,594...41,197,803
JBrowse link
G Csnk2a2 casein kinase 2 alpha 2 involved_in ISO (PMID:24912190) ParkinsonsUK-UCL PMID:24912190 NCBI chr19:9,556,443...9,596,080
Ensembl chr19:9,556,260...9,596,080
JBrowse link
G Cttn cortactin involved_in IEA
ISO
GO_REF:0000107
(PMID:20457763)
Ensembl
RGD
PMID:20457763 GO_REF:0000107 NCBI chr 1:199,599,710...199,635,254
Ensembl chr 1:199,599,710...199,635,164
JBrowse link
G Dnm1l dynamin 1-like involved_in ISO UniProtKB:Q9BXM7 (PMID:19279012) RGD PMID:19279012 NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482
JBrowse link
G Fbxw7 F-box and WD repeat domain containing 7 involved_in ISO (PMID:24912190) RGD PMID:24912190 NCBI chr 2:170,149,706...170,311,536
Ensembl chr 2:170,149,694...170,309,941
JBrowse link
G Fkbp8 FKBP prolyl isomerase 8 involved_in ISO (PMID:28381481), (PMID:31908024) RGD PMID:28381481 PMID:31908024 NCBI chr16:18,895,608...18,902,648
Ensembl chr16:18,893,576...18,902,612
JBrowse link
G Fzd5 frizzled class receptor 5 involved_in ISO (PMID:24912190) ParkinsonsUK-UCL PMID:24912190 NCBI chr 9:66,113,096...66,120,276
Ensembl chr 9:66,113,112...66,121,457
JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha involved_in IEA
ISO
GO_REF:0000107
(PMID:24912190)
Ensembl
RGD
PMID:24912190 GO_REF:0000107 NCBI chr 1:80,815,843...80,825,732
Ensembl chr 1:80,815,850...80,825,802
JBrowse link
G Parl presenilin associated, rhomboid-like involved_in ISO (PMID:21355049) RGD PMID:21355049 NCBI chr11:80,594,059...80,620,506
Ensembl chr11:80,593,192...80,620,506
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 involved_in ISO (PMID:24912190) RGD PMID:24912190 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 involved_in ISO (PMID:24912190) ParkinsonsUK-UCL PMID:24912190 NCBI chr 7:113,663,202...113,720,850
Ensembl chr 7:113,663,202...113,720,848
JBrowse link
G Usp36 ubiquitin specific peptidase 36 involved_in ISO (PMID:24912190) ParkinsonsUK-UCL PMID:24912190 NCBI chr10:103,497,349...103,528,877
Ensembl chr10:103,497,349...103,528,877
JBrowse link
G Vdac1 voltage-dependent anion channel 1 involved_in ISO (PMID:25470454) RGD PMID:25470454 NCBI chr10:36,532,306...36,559,642
Ensembl chr10:36,532,244...36,559,640
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20075
    cellular process 19154
      process utilizing autophagic mechanism 560
        autophagy 560
          regulation of autophagy 318
            regulation of autophagy of mitochondrion 48
              negative regulation of autophagy of mitochondrion + 9
              positive regulation of autophagy of mitochondrion + 27
              regulation of mitophagy + 47
Path 2
Term Annotations click to browse term
  biological_process 20075
    biological regulation 13559
      regulation of biological process 13136
        regulation of cellular process 12773
          regulation of metabolic process 6747
            regulation of catabolic process 1110
              regulation of autophagy 318
                regulation of autophagy of mitochondrion 48
                  negative regulation of autophagy of mitochondrion + 9
                  positive regulation of autophagy of mitochondrion + 27
                  regulation of mitophagy + 47
paths to the root