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Pathways

ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of mitophagy
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Accession:GO:1901526 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of mitophagy.
Synonyms:exact_synonym: positive regulation of macromitophagy;   up-regulation of macromitophagy;   upregulation of macromitophagy
 narrow_synonym: activation of macromitophagy



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positive regulation of mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ambra1 autophagy and beclin 1 regulator 1 involved_in ISO
IEA
(PMID:30217973)
GO_REF:0000107
RGD
Ensembl
PMID:30217973 GO_REF:0000107 NCBI chr 3:98,156,626...98,345,876
Ensembl chr 3:98,156,652...98,345,872
JBrowse link
G Atg7 autophagy related 7 IMP RGD PMID:37042059 RGD:407532700 NCBI chr 4:149,390,000...149,597,534
Ensembl chr 4:149,391,390...149,598,319
JBrowse link
G Cers1 ceramide synthase 1 involved_in ISO (PMID:22922758) RGD PMID:22922758 NCBI chr16:19,131,271...19,146,480
Ensembl chr16:19,131,276...19,146,480
JBrowse link
G Dele1 DAP3 binding cell death enhancer 1 involved_in ISO
IEA
(PMID:38340717)
GO_REF:0000107
RGD
Ensembl
PMID:38340717 GO_REF:0000107 NCBI chr18:30,325,369...30,349,285
Ensembl chr18:30,336,308...30,349,938
JBrowse link
G Eif2ak1 eukaryotic translation initiation factor 2 alpha kinase 1 involved_in ISO
IEA
ISS
(PMID:38340717)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:38340717 GO_REF:0000024 GO_REF:0000107 NCBI chr12:15,824,431...15,858,266
Ensembl chr12:15,825,124...15,858,281
JBrowse link
G Fbxo7 F-box protein 7 involved_in IMP
IEA
ISO
PMID:26310625
GO_REF:0000107
(PMID:26310625)
Ensembl
RGD
PMID:26310625 PMID:26310625 GO_REF:0000107, RGD:11536096 NCBI chr 7:19,696,951...19,725,180
Ensembl chr 7:19,696,961...19,725,180
JBrowse link
G Gdf1 growth differentiation factor 1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr16:19,131,271...19,146,480
Ensembl chr16:19,131,276...19,146,480
JBrowse link
G Htt huntingtin involved_in IEA
ISO
GO_REF:0000107
(PMID:25686248)
Ensembl
RGD
PMID:25686248 GO_REF:0000107 NCBI chr14:80,070,456...80,219,668
Ensembl chr14:80,070,456...80,219,668
JBrowse link
G Irgm immunity-related GTPase M involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:33510463)
(PMID:21102437)
(PMID:32939830)
UniProt
Ensembl
RGD
PMID:21102437 PMID:32939830 PMID:33510463 GO_REF:0000024 GO_REF:0000107 NCBI chr10:33,734,640...33,742,720
Ensembl chr10:33,732,961...33,743,228
JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 involved_in ISO (PMID:31919280) RGD PMID:31919280 NCBI chr19:34,555,832...34,596,281
Ensembl chr19:34,555,832...34,722,846
JBrowse link
G Oma1 OMA1 zinc metallopeptidase acts_upstream_of_or_within ISO (PMID:38340717) RGD PMID:38340717 NCBI chr 5:123,312,038...123,455,540
Ensembl chr 5:123,312,766...123,366,005
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in IMP
IEA
ISO
GO_REF:0000107
(PMID:26310625)
Ensembl
RGD
PMID:26310625 PMID:28608965 GO_REF:0000107, RGD:13432560 NCBI chr 1:51,236,410...52,430,242
Ensembl chr 1:51,210,330...52,430,304
JBrowse link
G Slc25a4 solute carrier family 25 member 4 involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:31618756)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:31618756 GO_REF:0000024 GO_REF:0000107 NCBI chr16:52,805,521...52,809,316
Ensembl chr16:52,805,523...52,811,700
JBrowse link
G Slc25a5 solute carrier family 25 member 5 involved_in ISS
ISO
GO_REF:0000024
(PMID:31618756)
UniProt
RGD
PMID:31618756 GO_REF:0000024 NCBI chr  X:120,897,616...120,900,683
Ensembl chr  X:120,897,563...120,900,688
JBrowse link
G Stub1 STIP1 homology and U-box containing protein 1 involved_in IMP PMID:29934347 UniProt PMID:29934347 RGD:405650300 NCBI chr10:15,355,278...15,357,559
Ensembl chr10:15,355,279...15,357,559
JBrowse link
G Ube2a ubiquitin-conjugating enzyme E2A involved_in ISO
IEA
(PMID:23685073)
GO_REF:0000107
RGD
Ensembl
PMID:23685073 GO_REF:0000107 NCBI chr  X:120,979,993...120,990,773
Ensembl chr  X:120,978,790...120,990,750
JBrowse link
G Vps13d vacuolar protein sorting 13 homolog D involved_in ISO
IEA
(PMID:29307555)
GO_REF:0000107
RGD
Ensembl
PMID:29307555 GO_REF:0000107 NCBI chr 5:162,113,732...162,339,121
Ensembl chr 5:162,113,732...162,339,099
JBrowse link
positive regulation of type 2 mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp5if1 ATP synthase inhibitory factor subunit 1 involved_in ISO (PMID:24005319) RGD PMID:24005319 NCBI chr 5:150,022,960...150,026,677
Ensembl chr 5:150,022,960...150,026,677
JBrowse link
G Cdc37 cell division cycle 37, HSP90 cochaperone involved_in ISO (PMID:21855797) RGD PMID:21855797 NCBI chr 8:27,954,292...27,966,935
Ensembl chr 8:27,948,016...27,983,931
JBrowse link
G Gba1 glucosylceramidase beta 1 acts_upstream_of_or_within ISO
IEA
(PMID:23707074)
GO_REF:0000107
RGD
Ensembl
PMID:23707074 GO_REF:0000107 NCBI chr 2:176,902,141...176,916,015
Ensembl chr 2:176,907,154...176,916,985
JBrowse link
G Hdac6 histone deacetylase 6 involved_in ISO
IEA
UniProtKB:Q9JK66 (PMID:20457763)
GO_REF:0000107
RGD
Ensembl
PMID:20457763 GO_REF:0000107 NCBI chr  X:17,222,538...17,244,373
Ensembl chr  X:17,222,856...17,244,370
JBrowse link
G Hk2 hexokinase 2 involved_in ISO
IEA
(PMID:23962723)
GO_REF:0000107
RGD
Ensembl
PMID:23962723 GO_REF:0000107 NCBI chr 4:116,792,258...116,841,275
Ensembl chr 4:116,792,258...116,841,275
JBrowse link
G Huwe1 HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1 involved_in ISO (PMID:30217973) RGD PMID:30217973 NCBI chr  X:24,350,708...24,480,798
Ensembl chr  X:24,353,217...24,480,798
JBrowse link
G Mul1 mitochondrial E3 ubiquitin protein ligase 1 involved_in ISO
IEA
(PMID:24709290)
GO_REF:0000107
RGD
Ensembl
PMID:24709290 GO_REF:0000107 NCBI chr 5:155,936,112...155,945,163
Ensembl chr 5:155,936,111...155,945,163
JBrowse link
G Pink1 PTEN induced kinase 1 involved_in ISO
IEA
(PMID:20871098)
GO_REF:0000107
RGD
Ensembl
PMID:20871098 GO_REF:0000107 NCBI chr 5:155,813,838...155,825,950
Ensembl chr 5:155,813,838...155,825,950
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO
IEA
(PMID:20457763), (PMID:20871098), (PMID:23212910)
GO_REF:0000107
RGD
Ensembl
PMID:20457763 PMID:20871098 PMID:23212910 GO_REF:0000107 NCBI chr 1:51,236,410...52,430,242
Ensembl chr 1:51,210,330...52,430,304
JBrowse link
G Tomm7 translocase of outer mitochondrial membrane 7 involved_in ISO (PMID:24270810) RGD PMID:24270810 NCBI chr 4:12,197,503...12,204,344
Ensembl chr 4:12,197,491...12,204,343
JBrowse link
G Vdac1 voltage-dependent anion channel 1 involved_in ISO
IEA
(PMID:32047033)
GO_REF:0000107
RGD
Ensembl
PMID:32047033 GO_REF:0000107 NCBI chr10:37,029,377...37,060,542
Ensembl chr10:37,023,145...37,060,541
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20668
    cellular process 19605
      process utilizing autophagic mechanism 604
        autophagy 604
          positive regulation of autophagy 195
            positive regulation of autophagy of mitochondrion 29
              positive regulation of mitophagy 27
                positive regulation of type 2 mitophagy 11
Path 2
Term Annotations click to browse term
  biological_process 20668
    biological regulation 13898
      regulation of biological process 13474
        regulation of cellular process 13054
          regulation of metabolic process 6832
            positive regulation of metabolic process 3883
              positive regulation of catabolic process 663
                positive regulation of autophagy 195
                  positive regulation of macroautophagy 103
                    positive regulation of mitophagy 27
                      positive regulation of type 2 mitophagy 11
paths to the root