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ONTOLOGY REPORT - ANNOTATIONS


Term:hepatocyte apoptotic process
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Accession:GO:0097284 term browser browse the term
Definition:Any apoptotic process in a hepatocyte, the main structural component of the liver.
Synonyms:narrow_synonym: hepatocyte apoptosis



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hepatocyte apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adar adenosine deaminase, RNA-specific involved_in
acts_upstream_of
IEA
ISO
GO_REF:0000107
MGI:2176228|MGI:3032439|MGI:3032487 (PMID:14613934)
Ensembl
RGD
PMID:14613934 GO_REF:0000107 NCBI chr 2:175,138,391...175,178,280
Ensembl chr 2:175,138,403...175,178,282
JBrowse link
G Arf6 ARF GTPase 6 acts_upstream_of_or_within ISO MGI:3662650 (PMID:16880525) RGD PMID:16880525 NCBI chr 6:87,853,742...87,854,890
Ensembl chr 6:87,840,142...87,874,114
JBrowse link
G Atf2 activating transcription factor 2 involved_in IEA
ISO
GO_REF:0000107
MGI:2443472 (PMID:17699753)
Ensembl
RGD
PMID:17699753 GO_REF:0000107 NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236
JBrowse link
G Atf7 activating transcription factor 7 involved_in ISO MGI:109349 (PMID:17699753) RGD PMID:17699753 NCBI chr 7:133,660,491...133,750,902
Ensembl chr 7:133,663,294...133,750,848
JBrowse link
G Bcl2l1 Bcl2-like 1 acts_upstream_of_or_within ISO MGI:2158303 (PMID:10618441) RGD PMID:10618441 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
Ensembl chr 1:141,253,523...141,303,479
JBrowse link
G Bid BH3 interacting domain death agonist involved_in
acts_upstream_of_or_within
ISS
ISO
IEA
GO_REF:0000024
MGI:1929260|MGI:95484 (PMID:20436477)
GO_REF:0000107
(PMID:32029622)
UniProt
RGD
Ensembl
PMID:20436477 PMID:32029622 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
JBrowse link
G Casp6 caspase 6 involved_in ISO
IEA
ISS
(PMID:32029622)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:32029622 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502
JBrowse link
G Casp8 caspase 8 acts_upstream_of_or_within ISO MGI:2177602|MGI:3054930 (PMID:15322156) RGD PMID:15322156 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha IEP RGD PMID:19833194 RGD:9588622 NCBI chr 6:26,791,517...26,902,161
Ensembl chr 6:26,822,609...26,896,687
JBrowse link
G Fas Fas cell surface death receptor acts_upstream_of_or_within ISO MGI:108093|MGI:1929260 (PMID:20436477) RGD PMID:20436477 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta IDA RGD PMID:28638224 RGD:13792732 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Gsn gelsolin involved_in ISO
IEA
(PMID:22952982)
GO_REF:0000107
RGD
Ensembl
PMID:22952982 GO_REF:0000107 NCBI chr 3:18,585,166...18,638,404
Ensembl chr 3:18,585,172...18,638,402
JBrowse link
G Kcnn4 potassium calcium-activated channel subfamily N member 4 IMP RGD PMID:27354175 RGD:329955558 NCBI chr 1:79,956,380...79,974,354
Ensembl chr 1:79,959,322...79,974,340
JBrowse link
G Krt18 keratin 18 acts_upstream_of_or_within ISO MGI:2178045 (PMID:10747083) RGD PMID:10747083 NCBI chr 7:133,157,486...133,161,162
Ensembl chr 7:133,157,475...133,161,166
Ensembl chr10:133,157,475...133,161,166
JBrowse link
G Krt8 keratin 8 acts_upstream_of_or_within ISO MGI:2178042 (PMID:10747083) RGD PMID:10747083 NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728
JBrowse link
G Lims1 LIM zinc finger domain containing 1 acts_upstream_of ISO MGI:2385067 (PMID:24058607) RGD PMID:24058607 NCBI chr20:26,309,833...26,418,511
Ensembl chr20:26,309,895...26,418,500
JBrowse link
G Mtch2 mitochondrial carrier 2 acts_upstream_of_or_within ISO MGI:108093|MGI:95484 (PMID:20436477) RGD PMID:20436477 NCBI chr 3:76,830,549...76,850,189
Ensembl chr 3:76,830,413...76,850,189
JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma IMP RGD PMID:20675006 RGD:6482714 NCBI chr 6:48,766,778...48,802,098
Ensembl chr 6:48,766,864...48,802,043
JBrowse link
G Rb1 RB transcriptional corepressor 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1857242 (PMID:11549719)
Ensembl
RGD
PMID:11549719 GO_REF:0000107 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
JBrowse link
G Stk3 serine/threonine kinase 3 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:104798 (PMID:20080598)
Ensembl
RGD
PMID:20080598 GO_REF:0000107 NCBI chr 7:66,053,209...66,323,292
Ensembl chr 7:66,052,345...66,323,233
JBrowse link
G Stk4 serine/threonine kinase 4 acts_upstream_of_or_within ISO MGI:104798 (PMID:20080598)
MGI:1928487 (PMID:20080598)
RGD PMID:20080598 NCBI chr 3:152,745,958...152,827,747
Ensembl chr 3:152,745,681...152,827,744
JBrowse link
negative regulation of hepatocyte apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adar adenosine deaminase, RNA-specific involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2176228|MGI:3032439|MGI:3032487 (PMID:14613934)
Ensembl
RGD
PMID:14613934 GO_REF:0000107 NCBI chr 2:175,138,391...175,178,280
Ensembl chr 2:175,138,403...175,178,282
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator IMP RGD PMID:16167066 RGD:11341697 NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034
JBrowse link
G Igf1r insulin-like growth factor 1 receptor IMP RGD PMID:17531559 RGD:10046009 NCBI chr 1:121,549,831...121,838,548
Ensembl chr 1:121,550,743...121,831,777
JBrowse link
G Lims1 LIM zinc finger domain containing 1 acts_upstream_of_or_within ISO MGI:2385067 (PMID:24058607) RGD PMID:24058607 NCBI chr20:26,309,833...26,418,511
Ensembl chr20:26,309,895...26,418,500
JBrowse link
G Mir21 microRNA 21 IMP RNA:increased expression:liver RGD PMID:29187695 RGD:41410824 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha acts_upstream_of ISO (PMID:31574452) RGD PMID:31574452 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:32029622)
UniProt
RGD
PMID:32029622 GO_REF:0000024 NCBI chr 2:54,240,298...54,275,978
Ensembl chr 2:54,240,137...54,275,978
JBrowse link
G Prkaa2 protein kinase AMP-activated catalytic subunit alpha 2 involved_in IEA
ISO
GO_REF:0000107
(PMID:32029622)
Ensembl
RGD
PMID:32029622 GO_REF:0000107 NCBI chr 5:119,807,992...119,879,987
Ensembl chr 5:119,813,226...119,879,543
JBrowse link
G Rb1 RB transcriptional corepressor 1 IMP RGD PMID:8649852 RGD:8548471 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
JBrowse link
positive regulation of hepatocyte apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mir675 microRNA 675 acts_upstream_of ISO (PMID:31574452) RGD PMID:31574452 NCBI chr 1:197,732,275...197,732,358
Ensembl chr 1:197,732,275...197,732,358
JBrowse link
G Selplg selectin P ligand IMP RGD PMID:16365457 RGD:401717523 NCBI chr12:42,796,690...42,809,908
Ensembl chr12:42,796,580...42,812,585
JBrowse link
G Stk4 serine/threonine kinase 4 acts_upstream_of_or_within ISO MGI:1928487 (PMID:20080598) RGD PMID:20080598 NCBI chr 3:152,745,958...152,827,747
Ensembl chr 3:152,745,681...152,827,744
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20228
    cellular process 19289
      cell death 2194
        programmed cell death 2194
          apoptotic process 2119
            epithelial cell apoptotic process 111
              hepatocyte apoptotic process 29
                negative regulation of hepatocyte apoptotic process 9
                positive regulation of hepatocyte apoptotic process 3
                regulation of hepatocyte apoptotic process + 12
paths to the root