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ONTOLOGY REPORT - ANNOTATIONS

Term:lymphoid progenitor cell differentiation
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Accession:GO:0002320 term browser browse the term
Definition:The process in which a precursor cell type acquires the specialized features of a lymphoid progenitor cell. Lymphoid progenitor cells include progenitor cells for any of the lymphoid lineages.


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lymphoid progenitor cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Batf basic leucine zipper ATF-like transcription factor involved_in ISS
ISO		 GO_REF:0000024
(MGI:5448499|PMID:22385964)		 UniProt
RGD		 PMID:22385964 GO_REF:0000024 MGI:5448499 NCBI chr 6:105,353,715...105,376,051
Ensembl chr 6:105,353,715...105,376,051 		JBrowse link
G Bcl2 BCL2, apoptosis regulator involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2156165 (PMID:9028316)		 Ensembl
RGD		 PMID:9028316 GO_REF:0000107 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bmp4 bone morphogenetic protein 4 involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:12421925)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:12421925 GO_REF:0000024 GO_REF:0000107 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306 		JBrowse link
G Flt3 Fms related receptor tyrosine kinase 3 acts_upstream_of_or_within ISO MGI:96677 (PMID:7621074) RGD PMID:7621074 NCBI chr12:7,623,930...7,699,474
Ensembl chr12:7,623,930...7,699,474 		JBrowse link
G Hmga1 high mobility group AT-hook 1 acts_upstream_of_or_within ISO MGI:3697313 (PMID:15713121) RGD PMID:15713121 NCBI chr20:5,611,088...5,618,755
Ensembl chr20:5,611,694...5,618,752 		JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase acts_upstream_of_or_within ISO MGI:95559 (PMID:7621074) RGD PMID:7621074 NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652 		JBrowse link
G Shh sonic hedgehog signaling molecule involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(MGI:3029054|PMID:14764698)
(PMID:14764698)		 Ensembl
UniProt
RGD		 PMID:14764698 GO_REF:0000024 GO_REF:0000107 MGI:3029054 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170 		JBrowse link
G Spi1 Spi-1 proto-oncogene acts_upstream_of_or_within ISO MGI:1930970 (PMID:9133423) RGD PMID:9133423 NCBI chr 3:77,059,744...77,093,730
Ensembl chr 3:77,073,012...77,092,393 		JBrowse link
G Trex1 three prime repair exonuclease 1 acts_upstream_of_or_within ISO MGI:5751220 (PMID:25848017) RGD PMID:25848017 NCBI chr 8:109,706,613...109,707,913
Ensembl chr 8:109,706,613...109,708,796 		JBrowse link
negative regulation of lymphoid progenitor cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pcid2 PCI domain containing 2 involved_in ISO (MGI:6106288|PMID:29138493) RGD PMID:29138493 MGI:6106288 NCBI chr16:76,423,245...76,448,712
Ensembl chr16:76,423,245...76,448,712 		JBrowse link
negative regulation of pro-B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hes1 hes family bHLH transcription factor 1 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:12032823)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:12032823 GO_REF:0000024 GO_REF:0000107 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192 		JBrowse link
G Hes5 hes family bHLH transcription factor 5 involved_in IMP PMID:12032823 UniProt PMID:12032823 RGD:8553570 NCBI chr 5:165,522,138...165,523,684
Ensembl chr 5:165,522,234...165,523,001 		JBrowse link
G Notch1 notch receptor 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5319620|PMID:12032823)		 UniProt
RGD		 PMID:12032823 GO_REF:0000024 MGI:5319620 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
positive regulation of lymphoid progenitor cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Znhit1 zinc finger, HIT-type containing 1 involved_in ISO (MGI:6106288|PMID:29138493) RGD PMID:29138493 MGI:6106288 NCBI chr12:19,686,606...19,692,880
Ensembl chr12:19,686,148...19,692,880 		JBrowse link
positive regulation of pro-B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nudt21 nudix hydrolase 21 involved_in ISS
ISO		 GO_REF:0000024
(MGI:6110185|PMID:29249356)		 UniProt
RGD		 PMID:29249356 GO_REF:0000024 MGI:6110185 NCBI chr19:10,974,800...10,993,841
Ensembl chr19:10,974,241...10,991,682 		JBrowse link
positive regulation of pro-T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Zbtb1 zinc finger and BTB domain containing 1 involved_in ISO (MGI:5446979|PMID:22753936) RGD PMID:22753936 MGI:5446979 NCBI chr 6:95,096,838...95,125,811
Ensembl chr 6:95,096,387...95,118,996 		JBrowse link
pro-B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Flt3 Fms related receptor tyrosine kinase 3 involved_in
acts_upstream_of_or_within		 ISO (MGI:4946600|PMID:21228325)
MGI:2384051 (PMID:7621074)		 RGD PMID:7621074 PMID:21228325 MGI:4946600 NCBI chr12:7,623,930...7,699,474
Ensembl chr12:7,623,930...7,699,474 		JBrowse link
G Lig4 DNA ligase 4 acts_upstream_of_or_within ISO MGI:1857732 (PMID:10911993), (PMID:9823897) RGD PMID:9823897 PMID:10911993 NCBI chr16:79,518,393...79,526,956
Ensembl chr16:79,518,312...79,527,040 		JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit acts_upstream_of_or_within ISO MGI:2383951 (PMID:9768755) RGD PMID:9768755 NCBI chr11:85,040,790...85,258,357
Ensembl chr11:85,040,792...85,257,952 		JBrowse link
G Sox4 SRY-box transcription factor 4 involved_in ISO (MGI:80229|PMID:8614465) RGD PMID:8614465 MGI:80229 NCBI chr17:35,667,809...35,672,515
Ensembl chr17:35,667,537...35,673,665 		JBrowse link
G Xrcc4 X-ray repair cross complementing 4 acts_upstream_of_or_within ISO MGI:1926771 (PMID:9875844) RGD PMID:9875844 NCBI chr 2:20,948,464...21,197,705
Ensembl chr 2:20,951,200...21,197,808 		JBrowse link
pro-T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Flt3 Fms related receptor tyrosine kinase 3 acts_upstream_of_or_within ISO MGI:2384051 (PMID:7621074) RGD PMID:7621074 NCBI chr12:7,623,930...7,699,474
Ensembl chr12:7,623,930...7,699,474 		JBrowse link
G Gata3 GATA binding protein 3 acts_upstream_of_or_within ISO MGI:2181200|MGI:3696958|MGI:4418042 (PMID:19934022) RGD PMID:19934022 NCBI chr17:68,643,760...68,666,000
Ensembl chr17:68,643,873...68,665,391 		JBrowse link
G Spi1 Spi-1 proto-oncogene involved_in ISO (MGI:6508514|PMID:30171019) RGD PMID:30171019 MGI:6508514 NCBI chr 3:77,059,744...77,093,730
Ensembl chr 3:77,073,012...77,092,393 		JBrowse link
regulation of lymphoid progenitor cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ankle1 ankyrin repeat and LEM domain containing 1 involved_in ISO (MGI:5800654|PMID:27010503) RGD PMID:27010503 MGI:5800654 NCBI chr16:18,076,413...18,082,356
Ensembl chr16:18,076,492...18,083,729 		JBrowse link
regulation of pro-B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Flcn folliculin involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
MGI:3774414 (PMID:22709692)		 UniProt
RGD		 PMID:22709692 GO_REF:0000024 NCBI chr10:44,588,621...44,607,808
Ensembl chr10:44,588,624...44,607,769 		JBrowse link
G Fnip1 folliculin interacting protein 1 involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
MGI:5445116 (PMID:22709692)		 UniProt
RGD		 PMID:22709692 GO_REF:0000024 NCBI chr10:38,567,728...38,650,824
Ensembl chr10:38,567,729...38,650,824 		JBrowse link
G Sos1 SOS Ras/Rac guanine nucleotide exchange factor 1 acts_upstream_of_or_within ISO MGI:98355 (PMID:24043312) RGD PMID:24043312 NCBI chr 6:14,533,870...14,613,348
Ensembl chr 6:14,533,360...14,611,107 		JBrowse link
G Sos2 SOS Ras/Rho guanine nucleotide exchange factor 2 acts_upstream_of_or_within ISO MGI:98355 (PMID:24043312) RGD PMID:24043312 NCBI chr 6:88,042,966...88,156,140
Ensembl chr 6:88,042,966...88,156,692 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19692
    cellular process 18168
      cellular developmental process 4695
        cell differentiation 4694
          hematopoietic progenitor cell differentiation 179
            lymphoid progenitor cell differentiation 26
              natural killer cell progenitor differentiation 0
              negative regulation of lymphoid progenitor cell differentiation + 4
              positive regulation of lymphoid progenitor cell differentiation + 3
              pro-B cell differentiation + 13
              pro-T cell differentiation + 4
              regulation of lymphoid progenitor cell differentiation + 12
Path 2
Term Annotations click to browse term
  biological_process 19692
    cellular process 18168
      cellular developmental process 4695
        cell differentiation 4694
          cell development 3269
            hemopoiesis 1061
              hematopoietic progenitor cell differentiation 179
                lymphoid progenitor cell differentiation 26
                  natural killer cell progenitor differentiation 0
                  negative regulation of lymphoid progenitor cell differentiation + 4
                  positive regulation of lymphoid progenitor cell differentiation + 3
                  pro-B cell differentiation + 13
                  pro-T cell differentiation + 4
                  regulation of lymphoid progenitor cell differentiation + 12
paths to the root