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ONTOLOGY REPORT - ANNOTATIONS


Term:pro-T cell differentiation
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Accession:GO:0002572 term browser browse the term
Definition:The process in which a precursor cell type acquires the specialized features of a pro-T cell. Pro-T cells are the earliest stage of the T cell lineage but are not fully committed.
Synonyms:exact_synonym: pro-T lymphocyte differentiation



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pro-T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Flt3 Fms related receptor tyrosine kinase 3 acts_upstream_of_or_within ISO MGI:2384051 (PMID:7621074) RGD PMID:7621074 NCBI chr12:7,623,930...7,699,474
Ensembl chr12:7,623,930...7,699,474
JBrowse link
G Gata3 GATA binding protein 3 acts_upstream_of_or_within ISO MGI:2181200|MGI:3696958|MGI:4418042 (PMID:19934022) RGD PMID:19934022 NCBI chr17:68,643,760...68,666,000
Ensembl chr17:68,643,873...68,665,391
JBrowse link
G Spi1 Spi-1 proto-oncogene involved_in ISO (MGI:6508514|PMID:30171019) RGD PMID:30171019 MGI:6508514 NCBI chr 3:77,059,744...77,093,730
Ensembl chr 3:77,073,012...77,092,393
JBrowse link
positive regulation of pro-T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Zbtb1 zinc finger and BTB domain containing 1 involved_in ISO (MGI:5446979|PMID:22753936) RGD PMID:22753936 MGI:5446979 NCBI chr 6:95,096,838...95,125,811
Ensembl chr 6:95,096,387...95,118,996
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20292
    immune system process 2982
      leukocyte activation 1048
        lymphocyte activation 847
          T cell activation 595
            T cell differentiation 323
              pro-T cell differentiation 4
                negative regulation of pro-T cell differentiation 0
                positive regulation of pro-T cell differentiation 1
                pro-T cell lineage commitment 0
                regulation of pro-T cell differentiation + 1
Path 2
Term Annotations click to browse term
  biological_process 20292
    cellular process 18769
      cellular developmental process 4747
        cell differentiation 4746
          cell development 3304
            hemopoiesis 1062
              leukocyte differentiation 674
                mononuclear cell differentiation 543
                  lymphocyte differentiation 447
                    T cell differentiation 323
                      pro-T cell differentiation 4
                        negative regulation of pro-T cell differentiation 0
                        positive regulation of pro-T cell differentiation 1
                        pro-T cell lineage commitment 0
                        regulation of pro-T cell differentiation + 1
paths to the root