Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:tolcapone
go back to main search page
Accession:CHEBI:63630 term browser browse the term
Definition:Benzophenone substituted on one of the phenyl rings at C-3 and C-4 by hydroxy groups and at C-5 by a nitro group, and on the other phenyl ring by a methyl group at C-4. It is an inhibitor of catechol O-methyltransferase.
Synonyms:exact_synonym: (3,4-dihydroxy-5-nitrophenyl)(4-methylphenyl)methanone
 related_synonym: 3,4-dihydroxy-5-nitro-4'-methylbenzophenone;   4'-methyl-3,4-dihydroxy-5-nitrobenzophenone;   Formula=C14H11NO5;   InChI=1S/C14H11NO5/c1-8-2-4-9(5-3-8)13(17)10-6-11(15(19)20)14(18)12(16)7-10/h2-7,16,18H,1H3;   InChIKey=MIQPIUSUKVNLNT-UHFFFAOYSA-N;   SMILES=Cc1ccc(cc1)C(=O)c1cc(O)c(O)c(c1)[N+]([O-])=O
 alt_id: CHEBI:9617
 xref: DrugBank:DB00323;   Drug_Central:2697;   KEGG:D00786;   LINCS:LSM-5282
 xref_mesh: MESH:C066340
 xref: PMID:20381177;   PMID:20502133;   PMID:21521027;   PMID:22136163;   Patent:EP237929;   Patent:US5236952;   Reaxys:8151577;   Wikipedia:Tolcapone


show annotations for term's descendants           Sort by:
tolcapone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aadac arylacetamide deacetylase decreases expression EXP tolcapone results in decreased expression of AADAC mRNA CTD PMID:24136188 NCBI chr 2:144,163,436...144,186,086
Ensembl chr 2:144,135,319...144,174,734 		JBrowse link
G Aars1 alanyl-tRNA synthetase 1 increases expression EXP Tolcapone results in increased expression of AARS1 mRNA CTD PMID:24136188 NCBI chr19:38,999,130...39,021,152
Ensembl chr19:38,999,163...39,021,147 		JBrowse link
G Abcb11 ATP binding cassette subfamily B member 11 decreases activity ISO tolcapone results in decreased activity of ABCB11 protein CTD PMID:20829430 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730 		JBrowse link
G Abcd2 ATP binding cassette subfamily D member 2 affects binding EXP tolcapone binds to ABCD2 protein CTD PMID:19783845 NCBI chr 7:122,263,034...122,311,642
Ensembl chr 7:122,263,032...122,311,642 		JBrowse link
G Abhd10 abhydrolase domain containing 10, depalmitoylase affects binding EXP tolcapone binds to ABHD10 protein CTD PMID:19783845 NCBI chr11:55,081,273...55,095,044
Ensembl chr11:55,081,049...55,107,866 		JBrowse link
G Acat2 acetyl-CoA acetyltransferase 2 increases expression EXP tolcapone results in increased expression of ACAT2 mRNA CTD PMID:24136188 NCBI chr 1:47,695,833...47,713,879
Ensembl chr 1:47,695,788...47,752,821 		JBrowse link
G Acox3 acyl-CoA oxidase 3, pristanoyl affects binding EXP tolcapone binds to ACOX3 protein CTD PMID:19783845 NCBI chr14:75,133,986...75,176,767
Ensembl chr14:75,094,676...75,176,205 		JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 affects binding
decreases expression		 EXP
ISO		 tolcapone binds to ACSL1 protein
tolcapone results in decreased expression of ACSL1 mRNA; tolcapone results in decreased expression of ACSL1 protein		 CTD PMID:19783845 PMID:29688484 NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541 		JBrowse link
G Acsl5 acyl-CoA synthetase long-chain family member 5 decreases expression ISO tolcapone results in decreased expression of ACSL5 protein CTD PMID:29688484 NCBI chr 1:254,289,513...254,336,608
Ensembl chr 1:254,292,521...254,336,607 		JBrowse link
G Acss2 acyl-CoA synthetase short-chain family member 2 increases expression EXP tolcapone results in increased expression of ACSS2 mRNA CTD PMID:24136188 NCBI chr 3:144,003,808...144,047,452
Ensembl chr 3:144,004,336...144,059,675 		JBrowse link
G Acta2 actin alpha 2, smooth muscle affects binding EXP tolcapone binds to ACTA2 protein CTD PMID:19783845 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554 		JBrowse link
G Adprhl1 ADP-ribosylhydrolase like 1 affects binding EXP tolcapone binds to ADPRHL1 protein CTD PMID:19783845 NCBI chr16:76,283,186...76,315,075
Ensembl chr16:76,283,103...76,354,440 		JBrowse link
G Aga aspartylglucosaminidase decreases expression EXP tolcapone results in decreased expression of AGA mRNA CTD PMID:24136188 NCBI chr16:38,504,661...38,516,607
Ensembl chr16:38,504,663...38,516,606 		JBrowse link
G Aif1 allograft inflammatory factor 1 decreases expression EXP tolcapone results in decreased expression of AIF1 mRNA CTD PMID:24136188 NCBI chr20:3,646,784...3,652,670
Ensembl chr20:3,646,777...3,652,668 		JBrowse link
G Ak2 adenylate kinase 2 affects binding EXP tolcapone binds to AK2 protein CTD PMID:19783845 NCBI chr 5:141,308,650...141,364,633
Ensembl chr 5:141,346,063...141,364,632 		JBrowse link
G Akr1c1 aldo-keto reductase family 1, member C1 affects binding EXP Tolcapone binds to AKR1C1 protein CTD PMID:19783845 NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326 		JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 decreases expression EXP tolcapone results in decreased expression of AKR1C3 mRNA CTD PMID:24136188 NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873 		JBrowse link
G Akr1d1 aldo-keto reductase family 1, member D1 affects binding EXP tolcapone binds to AKR1D1 protein CTD PMID:19783845 NCBI chr 4:66,154,246...66,187,505
Ensembl chr 4:66,154,248...66,186,372 		JBrowse link
G Aldh18a1 aldehyde dehydrogenase 18 family, member A1 affects binding EXP tolcapone binds to ALDH18A1 protein CTD PMID:19783845 NCBI chr 1:239,375,657...239,407,956
Ensembl chr 1:239,375,669...239,407,890 		JBrowse link
G Aldh1b1 aldehyde dehydrogenase 1 family, member B1 affects binding EXP tolcapone binds to ALDH1B1 protein CTD PMID:19783845 NCBI chr 5:60,063,370...60,068,378
Ensembl chr 5:60,063,225...60,068,378 		JBrowse link
G Aldh1l1 aldehyde dehydrogenase 1 family, member L1 increases expression EXP tolcapone results in increased expression of ALDH1L1 mRNA CTD PMID:24136188 NCBI chr 4:123,059,989...123,106,471
Ensembl chr 4:123,060,008...123,106,465 		JBrowse link
G Aldh3a2 aldehyde dehydrogenase 3 family, member A2 affects binding EXP tolcapone binds to ALDH3A2 protein CTD PMID:19783845 NCBI chr10:45,928,313...45,949,366
Ensembl chr10:45,908,524...45,949,281 		JBrowse link
G Alg13 ALG13, UDP-N-acetylglucosaminyltransferase subunit decreases expression EXP Tolcapone results in decreased expression of ALG13 mRNA CTD PMID:24136188 NCBI chr  X:107,906,320...107,968,232
Ensembl chr  X:107,885,093...107,942,695 		JBrowse link
G Amfr autocrine motility factor receptor increases expression EXP tolcapone results in increased expression of AMFR mRNA CTD PMID:24136188 NCBI chr19:10,996,705...11,032,260
Ensembl chr19:10,996,099...11,032,247 		JBrowse link
G Apmap adipocyte plasma membrane associated protein affects binding EXP tolcapone binds to APMAP protein CTD PMID:19783845 NCBI chr 3:139,409,021...139,437,296
Ensembl chr 3:139,409,022...139,437,341 		JBrowse link
G Apoa1 apolipoprotein A1 affects binding EXP tolcapone binds to APOA1 protein CTD PMID:19783845 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035 		JBrowse link
G Apob apolipoprotein B decreases expression
decreases secretion		 ISO tolcapone results in decreased expression of APOB mRNA
tolcapone results in decreased secretion of APOB protein alternative form		 CTD PMID:29688484 NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497 		JBrowse link
G Apoc2 apolipoprotein C2 decreases expression EXP tolcapone results in decreased expression of APOC2 mRNA CTD PMID:24136188 NCBI chr 1:79,329,429...79,334,397
Ensembl chr 1:79,329,428...79,334,476 		JBrowse link
G Apoe apolipoprotein E affects binding EXP tolcapone binds to APOE protein CTD PMID:19783845 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932 		JBrowse link
G Apool apolipoprotein O-like decreases expression EXP tolcapone results in decreased expression of APOOL mRNA CTD PMID:24136188 NCBI chr  X:77,377,723...77,443,672
Ensembl chr  X:77,377,781...77,443,900 		JBrowse link
G Arf4 ADP-ribosylation factor 4 affects binding EXP tolcapone binds to ARF4 protein CTD PMID:19783845 NCBI chr16:1,896,692...1,913,267
Ensembl chr16:1,896,546...1,913,261 		JBrowse link
G Arl1 ADP-ribosylation factor like GTPase 1 affects binding EXP tolcapone binds to ARL1 protein CTD PMID:19783845 NCBI chr 7:23,120,004...23,131,173
Ensembl chr 7:23,119,589...23,131,898 		JBrowse link
G Atad1 ATPase family, AAA domain containing 1 affects binding EXP tolcapone binds to ATAD1 protein CTD PMID:19783845 NCBI chr 1:230,544,227...230,610,524
Ensembl chr 1:230,544,047...230,596,548 		JBrowse link
G Atad3a ATPase family, AAA domain containing 3A affects binding EXP tolcapone binds to ATAD3A protein CTD PMID:19783845 NCBI chr 5:166,350,302...166,370,492
Ensembl chr 5:166,350,304...166,370,482 		JBrowse link
G Atf5 activating transcription factor 5 increases expression EXP tolcapone results in increased expression of ATF5 mRNA CTD PMID:24136188 NCBI chr 1:95,295,602...95,299,755
Ensembl chr 1:95,295,610...95,299,707 		JBrowse link
G Atp1b3 ATPase Na+/K+ transporting subunit beta 3 affects binding EXP tolcapone binds to ATP1B3 protein CTD PMID:19783845 NCBI chr 8:96,910,265...96,941,592
Ensembl chr 8:96,910,309...96,941,598 		JBrowse link
G Atp5f1b ATP synthase F1 subunit beta affects binding EXP tolcapone binds to ATP5F1B protein CTD PMID:19783845 NCBI chr 7:515,454...521,858
Ensembl chr 7:515,460...567,273 		JBrowse link
G Atp5f1c ATP synthase F1 subunit gamma affects binding EXP Tolcapone binds to ATP5F1C protein CTD PMID:19783845 NCBI chr17:68,423,927...68,446,169
Ensembl chr17:68,423,909...68,608,367 		JBrowse link
G Atp5f1e ATP synthase F1 subunit epsilon decreases expression EXP tolcapone results in decreased expression of ATP5F1E mRNA CTD PMID:24136188 NCBI chr 3:163,259,072...163,261,974
Ensembl chr 3:163,260,476...163,261,450 		JBrowse link
G Atp5me ATP synthase membrane subunit e decreases expression
affects binding		 EXP tolcapone results in decreased expression of ATP5ME mRNA
tolcapone binds to ATP5ME protein		 CTD PMID:19783845 PMID:24136188 NCBI chr14:1,319,868...1,320,996
Ensembl chr14:1,319,868...1,321,013 		JBrowse link
G Atp5mf ATP synthase membrane subunit f affects binding EXP tolcapone binds to ATP5MF protein CTD PMID:19783845 NCBI chr12:9,421,665...9,428,236
Ensembl chr12:9,421,579...9,428,236 		JBrowse link
G Atp5mg ATP synthase membrane subunit G decreases expression
affects binding		 EXP tolcapone results in decreased expression of ATP5MG mRNA
tolcapone binds to ATP5MG protein		 CTD PMID:19783845 PMID:24136188 NCBI chr 8:45,225,680...45,233,630
Ensembl chr 8:45,225,686...45,233,559 		JBrowse link
G Atp5mk ATP synthase membrane subunit K decreases expression EXP Tolcapone results in decreased expression of ATP5MK mRNA CTD PMID:24136188 NCBI chr 1:245,973,910...245,980,702
Ensembl chr 1:245,973,914...245,980,761
Ensembl chr10:245,973,914...245,980,761 		JBrowse link
G Atp5pf ATP synthase peripheral stalk subunit F6 decreases expression EXP tolcapone results in decreased expression of ATP5PF mRNA CTD PMID:24136188 NCBI chr11:23,881,594...23,889,581
Ensembl chr11:23,881,592...23,889,119 		JBrowse link
G Atp5po ATP synthase peripheral stalk subunit OSCP affects binding EXP tolcapone binds to ATP5PO protein CTD PMID:19783845 NCBI chr11:31,165,218...31,171,530
Ensembl chr11:31,165,217...31,171,592 		JBrowse link
G Auh AU RNA binding methylglutaconyl-CoA hydratase affects binding EXP tolcapone binds to AUH protein CTD PMID:19783845 NCBI chr17:12,329,522...12,424,882
Ensembl chr17:12,329,524...12,424,896 		JBrowse link
G Bbox1 gamma-butyrobetaine hydroxylase 1 decreases expression EXP tolcapone results in decreased expression of BBOX1 mRNA CTD PMID:24136188 NCBI chr 3:96,822,654...96,871,786
Ensembl chr 3:96,822,655...96,871,458 		JBrowse link
G Bcam basal cell adhesion molecule (Lutheran blood group) affects binding EXP tolcapone binds to BCAM protein CTD PMID:19783845 NCBI chr 1:79,415,016...79,429,403
Ensembl chr 1:79,415,017...79,429,403 		JBrowse link
G Bcap29 B-cell receptor-associated protein 29 decreases expression EXP tolcapone results in decreased expression of BCAP29 mRNA CTD PMID:24136188 NCBI chr 6:48,182,702...48,222,698
Ensembl chr 6:48,182,706...48,222,720 		JBrowse link
G Bcas2 BCAS2, pre-mRNA processing factor decreases expression EXP tolcapone results in decreased expression of BCAS2 mRNA CTD PMID:24136188 NCBI chr 2:190,692,503...190,700,386
Ensembl chr 2:190,692,461...190,700,389 		JBrowse link
G Bltp1 bridge-like lipid transfer protein family member 1 increases expression EXP Tolcapone results in increased expression of BLTP1 mRNA CTD PMID:24136188 NCBI chr 2:119,708,114...119,924,697
Ensembl chr 2:119,708,209...119,924,695 		JBrowse link
G Bmper BMP-binding endothelial regulator affects binding EXP tolcapone binds to BMPER protein CTD PMID:19783845 NCBI chr 8:21,732,225...21,977,261
Ensembl chr 8:21,732,225...21,977,256 		JBrowse link
G Bms1 BMS1 ribosome biogenesis factor affects binding EXP tolcapone binds to BMS1 protein CTD PMID:19783845 NCBI chr 4:151,558,163...151,595,187
Ensembl chr 4:151,558,163...151,595,127 		JBrowse link
G Bpgm bisphosphoglycerate mutase decreases expression EXP tolcapone results in decreased expression of BPGM mRNA CTD PMID:24136188 NCBI chr 4:63,139,730...63,168,581
Ensembl chr 4:63,140,018...63,168,581 		JBrowse link
G Btf3l4 basic transcription factor 3-like 4 decreases expression EXP tolcapone results in decreased expression of BTF3L4 mRNA CTD PMID:24136188 NCBI chr 5:123,567,902...123,587,527
Ensembl chr 5:123,567,907...123,586,866 		JBrowse link
G C1d C1D nuclear receptor corepressor decreases expression EXP tolcapone results in decreased expression of C1D mRNA CTD PMID:24136188 NCBI chr14:91,660,951...91,673,177
Ensembl chr14:91,660,989...91,672,852 		JBrowse link
G C1galt1c1 C1GALT1-specific chaperone 1 decreases expression EXP tolcapone results in decreased expression of C1GALT1C1 mRNA CTD PMID:24136188 NCBI chr  X:117,378,123...117,382,620
Ensembl chr  X:117,375,525...117,382,787 		JBrowse link
G C4b complement C4B increases expression EXP tolcapone results in increased expression of C4B mRNA CTD PMID:24136188 NCBI chr20:4,197,371...4,211,684
Ensembl chr20:4,197,366...4,211,681 		JBrowse link
G C5 complement C5 increases expression EXP tolcapone results in increased expression of C5 mRNA CTD PMID:24136188 NCBI chr 3:18,270,696...18,361,994
Ensembl chr 3:18,270,696...18,361,994 		JBrowse link
G C8a complement C8 alpha chain increases expression EXP tolcapone results in increased expression of C8A mRNA CTD PMID:24136188 NCBI chr 5:119,583,168...119,637,675
Ensembl chr 5:119,583,174...119,637,754 		JBrowse link
G C8h11orf71 similar to human chromosome 11 open reading frame 71 decreases expression EXP Tolcapone results in decreased expression of C8H11ORF71 mRNA CTD PMID:24136188 NCBI chr 8:48,838,556...48,838,970
Ensembl chr 8:48,838,100...48,842,270 		JBrowse link
G C8h15orf61 similar to human chromosome 15 open reading frame 61 decreases expression EXP Tolcapone results in decreased expression of C8H15ORF61 mRNA CTD PMID:24136188 NCBI chr 8:63,868,125...63,872,863
Ensembl chr 8:63,868,125...63,872,751 		JBrowse link
G Cbr4 carbonyl reductase 4 decreases expression EXP tolcapone results in decreased expression of CBR4 mRNA CTD PMID:24136188 NCBI chr16:28,629,928...28,684,230
Ensembl chr16:28,617,224...28,645,712 		JBrowse link
G Ccnl2 cyclin L2 increases expression EXP tolcapone results in increased expression of CCNL2 mRNA CTD PMID:24136188 NCBI chr 5:166,416,940...166,428,997
Ensembl chr 5:166,417,508...166,436,882 		JBrowse link
G Cct7 chaperonin containing TCP1 subunit 7 affects binding EXP tolcapone binds to CCT7 protein CTD PMID:19783845 NCBI chr 4:117,989,232...118,006,478
Ensembl chr 4:117,989,232...118,006,580 		JBrowse link
G Cd36 CD36 molecule increases expression ISO tolcapone results in increased expression of CD36 mRNA CTD PMID:29688484 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
G Cfb complement factor B increases expression EXP tolcapone results in increased expression of CFB mRNA CTD PMID:24136188 NCBI chr20:3,970,643...3,976,510
Ensembl chr20:3,951,474...3,976,505 		JBrowse link
G Chchd1 coiled-coil-helix-coiled-coil-helix domain containing 1 decreases expression EXP tolcapone results in decreased expression of CHCHD1 mRNA CTD PMID:24136188 NCBI chr15:3,592,719...3,593,901
Ensembl chr15:3,592,727...3,593,901 		JBrowse link
G Chchd7 coiled-coil-helix-coiled-coil-helix domain containing 7 decreases expression EXP tolcapone results in decreased expression of CHCHD7 mRNA CTD PMID:24136188 NCBI chr 5:16,957,127...16,961,682
Ensembl chr 5:16,957,188...16,961,184 		JBrowse link
G Chrac1 chromatin accessibility complex subunit 1 decreases expression EXP tolcapone results in decreased expression of CHRAC1 mRNA CTD PMID:24136188 NCBI chr 7:105,013,047...105,016,435
Ensembl chr 7:105,013,015...105,017,136 		JBrowse link
G Churc1 churchill domain containing 1 decreases expression EXP tolcapone results in decreased expression of CHURC1 mRNA CTD PMID:24136188 NCBI chr 6:95,464,488...95,485,208
Ensembl chr 6:95,470,683...95,619,586 		JBrowse link
G Ciao2a cytosolic iron-sulfur assembly component 2A decreases expression EXP tolcapone results in decreased expression of CIAO2A mRNA CTD PMID:24136188 NCBI chr 8:66,670,533...66,682,455
Ensembl chr 8:66,670,483...66,682,455 		JBrowse link
G Cidea cell death-inducing DFFA-like effector a increases expression ISO tolcapone results in increased expression of CIDEA mRNA CTD PMID:29688484 NCBI chr18:60,894,917...60,920,485
Ensembl chr18:60,894,874...60,920,481 		JBrowse link
G Cisd1 CDGSH iron sulfur domain 1 affects binding EXP tolcapone binds to CISD1 protein CTD PMID:19783845 NCBI chr20:17,255,302...17,268,688
Ensembl chr20:17,255,151...17,284,924 		JBrowse link
G Clec4a3 C-type lectin domain family 4, member A3 decreases expression EXP Tolcapone results in decreased expression of CLEC4A3 mRNA CTD PMID:24136188 NCBI chr 4:156,214,030...156,224,818
Ensembl chr 4:156,214,718...156,224,817 		JBrowse link
G Cltc clathrin heavy chain affects binding EXP tolcapone binds to CLTC protein CTD PMID:19783845 NCBI chr10:71,517,661...71,574,591
Ensembl chr10:71,517,663...71,573,737 		JBrowse link
G Cnih4 cornichon family member 4 decreases expression EXP tolcapone results in decreased expression of CNIH4 mRNA CTD PMID:24136188 NCBI chr13:92,910,315...92,926,428
Ensembl chr13:92,910,315...92,927,853 		JBrowse link
G Commd6 COMM domain containing 6 decreases expression EXP tolcapone results in decreased expression of COMMD6 mRNA CTD PMID:24136188 NCBI chr15:78,467,333...78,474,382
Ensembl chr15:78,467,804...78,474,382 		JBrowse link
G Comt catechol-O-methyltransferase decreases activity
affects binding
increases methylation
multiple interactions		 ISO
EXP		 tolcapone results in decreased activity of COMT protein
tolcapone binds to COMT protein
COMT protein results in increased methylation of tolcapone
[tolcapone results in decreased activity of COMT protein] promotes the reaction [Clozapine results in increased abundance of Dopamine]; [tolcapone results in decreased activity of COMT protein] which results in decreased abundance of Homovanillic Acid; [tolcapone results in decreased activity of COMT protein] which results in increased abundance of 3,4-Dihydroxyphenylacetic Acid; tolcapone inhibits the reaction [[COMT protein results in increased methylation of Epinephrine] which results in increased abundance of Metanephrine]
[tolcapone results in decreased activity of COMT protein] inhibits the reaction [Levodopa results in increased abundance of Homocysteine]; [tolcapone results in decreased activity of COMT protein] inhibits the reaction [Levodopa results in increased abundance of S-Adenosylmethionine]; [tolcapone results in decreased activity of COMT protein] which results in decreased abundance of Adenosine Triphosphate; [tolcapone results in decreased activity of COMT protein] which results in decreased abundance of Homovanillic Acid; [tolcapone results in decreased activity of COMT protein] which results in increased abundance of 3,4-Dihydroxyphenylacetic Acid; [tolcapone results in decreased activity of COMT protein] which results in increased abundance of Dopamine; [tolcapone results in decreased activity of COMT protein] which results in increased abundance of Epinephrine; [tolcapone results in decreased activity of COMT protein] which results in increased abundance of Levodopa; [tolcapone results in decreased activity of COMT protein] which results in increased abundance of Norepinephrine; tolcapone inhibits the reaction [COMT protein results in increased methylation of Levodopa]		 CTD PMID:2089102 PMID:7566641 PMID:7768073 PMID:8821542 PMID:9333106 More... NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642 		JBrowse link
G Copg1 COPI coat complex subunit gamma 1 affects binding EXP tolcapone binds to COPG1 protein CTD PMID:19783845 NCBI chr 4:120,366,540...120,392,502
Ensembl chr 4:120,366,542...120,415,616 		JBrowse link
G Copg2 COPI coat complex subunit gamma 2 decreases expression EXP tolcapone results in decreased expression of COPG2 mRNA CTD PMID:24136188 NCBI chr 4:59,366,086...59,501,591
Ensembl chr 4:59,366,086...59,501,618 		JBrowse link
G Coq10a coenzyme Q10A decreases expression EXP tolcapone results in decreased expression of COQ10A mRNA CTD PMID:24136188 NCBI chr 7:792,089...798,392
Ensembl chr 7:792,089...800,161 		JBrowse link
G Coq3 coenzyme Q3 methyltransferase decreases expression EXP tolcapone results in decreased expression of COQ3 mRNA CTD PMID:24136188 NCBI chr 5:35,429,567...35,460,613
Ensembl chr 5:35,429,574...35,460,607 		JBrowse link
G Cox6c cytochrome c oxidase subunit 6C affects binding
decreases expression		 EXP tolcapone binds to COX6C protein
tolcapone results in decreased expression of COX6C mRNA		 CTD PMID:19783845 PMID:24136188 NCBI chr 7:67,129,265...67,142,001
Ensembl chr 7:67,111,024...67,141,963 		JBrowse link
G Cox7a2 cytochrome c oxidase subunit 7A2 decreases expression EXP tolcapone results in decreased expression of COX7A2 mRNA CTD PMID:24136188 NCBI chr 8:80,716,824...80,720,922
Ensembl chr14:51,301,168...51,301,633
Ensembl chr 8:51,301,168...51,301,633 		JBrowse link
G Cox7b cytochrome c oxidase subunit 7B decreases expression EXP tolcapone results in decreased expression of COX7B mRNA CTD PMID:24136188 NCBI chr  X:71,083,486...71,089,733
Ensembl chr  X:71,083,456...71,089,732 		JBrowse link
G Cp ceruloplasmin increases expression EXP tolcapone results in increased expression of CP mRNA CTD PMID:24136188 NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075 		JBrowse link
G Crem cAMP responsive element modulator decreases expression EXP tolcapone results in decreased expression of CREM mRNA CTD PMID:24136188 NCBI chr17:54,238,889...54,305,989
Ensembl chr17:54,239,030...54,305,989 		JBrowse link
G Crip2 cysteine-rich protein 2 increases expression EXP tolcapone results in increased expression of CRIP2 mRNA CTD PMID:24136188 NCBI chr 6:132,221,120...132,226,066
Ensembl chr 6:132,221,082...132,226,065 		JBrowse link
G Cse1l chromosome segregation 1 like affects binding EXP tolcapone binds to CSE1L protein CTD PMID:19783845 NCBI chr 3:155,641,104...155,678,866
Ensembl chr 3:155,641,166...155,678,865 		JBrowse link
G Cstb cystatin B decreases expression EXP tolcapone results in decreased expression of CSTB mRNA CTD PMID:24136188 NCBI chr20:10,245,462...10,247,505
Ensembl chr20:10,245,462...10,247,526 		JBrowse link
G Cyc1 cytochrome c-1 affects binding EXP tolcapone binds to CYC1 protein CTD PMID:19783845 NCBI chr 7:108,067,106...108,069,483
Ensembl chr 7:108,067,115...108,069,479 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
decreases activity		 EXP
ISO		 tolcapone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]
Tolcapone results in decreased activity of CYP1A1 protein		 CTD PMID:18493746 PMID:33814510 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions
increases expression		 EXP
ISO		 tolcapone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]
tolcapone results in increased expression of CYP1A2 mRNA		 CTD PMID:18493746 PMID:24136188 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases activity ISO Tolcapone results in decreased activity of CYP1B1 protein CTD PMID:33814510 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases response to substance ISO CYP3A4 protein results in increased susceptibility to Tolcapone CTD PMID:21540358 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Cyp51 cytochrome P450, family 51 increases expression EXP tolcapone results in increased expression of CYP51 mRNA CTD PMID:24136188 NCBI chr 4:30,036,956...30,055,410
Ensembl chr 4:30,036,865...30,055,410 		JBrowse link
G Dap death-associated protein increases expression EXP tolcapone results in increased expression of DAP mRNA CTD PMID:24136188 NCBI chr 2:82,199,206...82,251,771
Ensembl chr 2:82,199,280...82,251,752 		JBrowse link
G Dctd dCMP deaminase affects binding EXP tolcapone binds to DCTD protein CTD PMID:19783845 NCBI chr16:44,066,952...44,098,654
Ensembl chr16:44,055,128...44,098,446 		JBrowse link
G Ddost dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit affects binding EXP tolcapone binds to DDOST protein CTD PMID:19783845 NCBI chr 5:150,522,297...150,529,413
Ensembl chr 5:150,522,242...150,529,413 		JBrowse link
G Ddx18 DEAD-box helicase 18 affects binding EXP tolcapone binds to DDX18 protein CTD PMID:19783845 NCBI chr13:32,729,697...32,743,161
Ensembl chr13:32,729,700...32,743,161 		JBrowse link
G Dhcr24 24-dehydrocholesterol reductase affects binding
increases expression		 EXP tolcapone binds to DHCR24 protein
tolcapone results in increased expression of DHCR24 mRNA		 CTD PMID:19783845 PMID:24136188 NCBI chr 5:121,344,552...121,371,124
Ensembl chr 5:121,344,575...121,371,137 		JBrowse link
G Dhcr7 7-dehydrocholesterol reductase affects binding EXP tolcapone binds to DHCR7 protein CTD PMID:19783845 NCBI chr 1:199,015,081...199,031,055
Ensembl chr 1:199,015,081...199,031,055 		JBrowse link
G Dmac1 distal membrane arm assembly component 1 decreases expression EXP tolcapone results in decreased expression of DMAC1 mRNA CTD PMID:24136188 NCBI chr 5:89,241,173...89,243,793
Ensembl chr 5:89,242,661...89,243,757 		JBrowse link
G Dnajc15 DnaJ heat shock protein family (Hsp40) member C15 decreases expression EXP tolcapone results in decreased expression of DNAJC15 mRNA CTD PMID:24136188 NCBI chr15:53,182,060...53,249,675
Ensembl chr15:53,184,855...53,249,675 		JBrowse link
G Dock11 dedicator of cytokinesis 11 decreases expression EXP tolcapone results in decreased expression of DOCK11 mRNA CTD PMID:24136188 NCBI chr  X:115,131,720...115,314,854
Ensembl chr  X:115,131,909...115,314,854 		JBrowse link
G Dpm3 dolichyl-phosphate mannosyltransferase subunit 3, regulatory decreases expression EXP tolcapone results in decreased expression of DPM3 mRNA CTD PMID:24136188 NCBI chr 2:174,676,532...174,677,047
Ensembl chr 2:174,676,363...174,677,668
Ensembl chr15:174,676,363...174,677,668 		JBrowse link
G Dpy30 dpy-30 histone methyltransferase complex regulatory subunit decreases expression EXP tolcapone results in decreased expression of DPY30 mRNA CTD PMID:24136188 NCBI chr 6:21,120,947...21,141,720
Ensembl chr 6:21,120,947...21,141,432 		JBrowse link
G Dtymk deoxythymidylate kinase decreases expression EXP tolcapone results in decreased expression of DTYMK mRNA CTD PMID:24136188 NCBI chr 9:94,315,552...94,324,386
Ensembl chr 9:94,315,552...94,324,870 		JBrowse link
G Dynll1 dynein light chain LC8-type 1 decreases expression EXP tolcapone results in decreased expression of DYNLL1 mRNA CTD PMID:24136188 NCBI chr12:41,312,365...41,316,157
Ensembl chr12:41,312,367...41,314,741 		JBrowse link
G Dynlt3 dynein light chain Tctex-type 3 decreases expression EXP tolcapone results in decreased expression of DYNLT3 mRNA CTD PMID:24136188 NCBI chr  X:13,327,933...13,337,139
Ensembl chr  X:13,327,892...13,337,139 		JBrowse link
G Ebp EBP, cholestenol delta-isomerase increases expression EXP tolcapone results in increased expression of EBP mRNA CTD PMID:24136188 NCBI chr  X:14,299,427...14,305,826
Ensembl chr  X:14,299,448...14,305,826 		JBrowse link
G Echs1 enoyl-CoA hydratase, short chain 1 affects binding EXP tolcapone binds to ECHS1 protein CTD PMID:19783845 NCBI chr 1:194,895,036...194,903,863
Ensembl chr 1:194,895,036...194,903,884 		JBrowse link
G Eloc elongin C decreases expression EXP tolcapone results in decreased expression of ELOC mRNA CTD PMID:24136188 NCBI chr 5:2,661,527...2,677,893
Ensembl chr 5:2,661,724...2,677,890 		JBrowse link
G Ereg epiregulin decreases expression ISO Tolcapone results in decreased expression of EREG mRNA CTD PMID:32816093 NCBI chr14:17,027,287...17,041,062
Ensembl chr14:17,027,287...17,041,062 		JBrowse link
G F5 coagulation factor V increases expression EXP tolcapone results in increased expression of F5 mRNA CTD PMID:24136188 NCBI chr13:76,513,509...76,583,106
Ensembl chr13:76,513,255...76,582,317 		JBrowse link
G Fam162a family with sequence similarity 162, member A affects binding EXP tolcapone binds to FAM162A protein CTD PMID:19783845 NCBI chr11:64,680,978...64,709,865
Ensembl chr11:64,680,323...64,711,239 		JBrowse link
G Fbll1 fibrillarin-like 1 affects binding EXP tolcapone binds to FBLL1 protein CTD PMID:19783845 NCBI chr10:20,258,656...20,260,299
Ensembl chr10:20,258,656...20,260,299 		JBrowse link
G Fcf1 Fcf1 rRNA-processing protein decreases expression EXP tolcapone results in decreased expression of FCF1 mRNA CTD PMID:24136188 NCBI chr 6:104,617,780...104,629,643
Ensembl chr 6:104,617,770...104,629,643 		JBrowse link
G Fga fibrinogen alpha chain affects binding EXP tolcapone binds to FGA protein CTD PMID:19783845 NCBI chr 2:168,374,120...168,381,523
Ensembl chr 2:168,374,120...168,381,528 		JBrowse link
G Fmc1 formation of mitochondrial complex V assembly factor 1 decreases expression EXP tolcapone results in decreased expression of FMC1 mRNA CTD PMID:24136188 NCBI chr 4:67,274,104...67,282,140
Ensembl chr 4:67,274,104...67,282,140 		JBrowse link
G Gcdh glutaryl-CoA dehydrogenase affects binding EXP tolcapone binds to GCDH protein CTD PMID:19783845 NCBI chr19:23,263,215...23,269,689
Ensembl chr19:23,263,264...23,269,681 		JBrowse link
G Glg1 golgi glycoprotein 1 affects binding EXP tolcapone binds to GLG1 protein CTD PMID:19783845 NCBI chr19:39,124,892...39,224,178
Ensembl chr19:39,124,641...39,224,178 		JBrowse link
G Gmfg glia maturation factor, gamma decreases expression EXP tolcapone results in decreased expression of GMFG mRNA CTD PMID:24136188 NCBI chr 1:83,728,797...83,739,189
Ensembl chr 1:83,728,776...83,739,183 		JBrowse link
G Gng10 G protein subunit gamma 10 decreases expression EXP tolcapone results in decreased expression of GNG10 mRNA CTD PMID:24136188 NCBI chr 5:73,856,124...73,863,017
Ensembl chr 5:73,856,164...73,863,012
Ensembl chr 5:73,856,164...73,863,012 		JBrowse link
G Gng5 G protein subunit gamma 5 decreases expression EXP tolcapone results in decreased expression of GNG5 mRNA CTD PMID:24136188 NCBI chr 2:235,394,680...235,403,177
Ensembl chr 1:77,292,043...77,292,513 		JBrowse link
G Gpc3 glypican 3 affects binding EXP tolcapone binds to GPC3 protein CTD PMID:19783845 NCBI chr  X:131,868,986...132,236,824
Ensembl chr  X:131,868,990...132,236,798 		JBrowse link
G Gtf2h5 general transcription factor IIH subunit 5 decreases expression EXP tolcapone results in decreased expression of GTF2H5 mRNA CTD PMID:24136188 NCBI chr 1:46,656,804...46,663,512
Ensembl chr 1:46,656,859...46,664,939 		JBrowse link
G H2az2 H2A.Z variant histone 2 affects binding EXP Tolcapone binds to H2AZ2 protein CTD PMID:19783845 NCBI chr14:81,293,304...81,312,209
Ensembl chr14:81,293,299...81,312,144 		JBrowse link
G Hbb hemoglobin subunit beta affects binding EXP tolcapone binds to HBB protein CTD PMID:19783845 NCBI chr 1:158,250,421...158,251,832
Ensembl chr 1:158,120,200...158,252,012 		JBrowse link
G Higd1a HIG1 hypoxia inducible domain family, member 1A decreases expression EXP tolcapone results in decreased expression of HIGD1A mRNA CTD PMID:24136188 NCBI chr 8:121,514,152...121,523,382
Ensembl chr 8:121,514,156...121,523,443 		JBrowse link
G Hint3 histidine triad nucleotide binding protein 3 decreases expression EXP tolcapone results in decreased expression of HINT3 mRNA CTD PMID:24136188 NCBI chr 1:27,035,936...27,045,799
Ensembl chr 1:27,035,905...27,047,721 		JBrowse link
G Hist1h4b histone cluster 1 H4 family member B decreases expression EXP Tolcapone results in decreased expression of HIST1H4B mRNA CTD PMID:24136188 NCBI chr17:42,480,467...42,484,912
Ensembl chr17:42,480,313...42,485,370 		JBrowse link
G Hnrnph1 heterogeneous nuclear ribonucleoprotein H1 affects binding EXP tolcapone binds to HNRNPH1 protein CTD PMID:19783845 NCBI chr10:34,692,868...34,702,849
Ensembl chr10:34,693,555...34,702,846 		JBrowse link
G Hsd17b11 hydroxysteroid (17-beta) dehydrogenase 11 affects binding EXP tolcapone binds to HSD17B11 protein CTD PMID:19783845 NCBI chr14:5,693,304...5,743,157
Ensembl chr14:5,711,964...5,743,161 		JBrowse link
G Hsd17b12 hydroxysteroid (17-beta) dehydrogenase 12 affects binding EXP tolcapone binds to HSD17B12 protein CTD PMID:19783845 NCBI chr 3:79,990,048...80,113,556
Ensembl chr 3:79,990,056...80,113,617 		JBrowse link
G Hsd17b13 hydroxysteroid (17-beta) dehydrogenase 13 affects binding EXP tolcapone binds to HSD17B13 protein CTD PMID:19783845 NCBI chr14:5,751,697...5,766,809
Ensembl chr14:5,752,132...5,768,166 		JBrowse link
G Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 affects binding EXP tolcapone binds to HSD17B4 protein CTD PMID:19783845 NCBI chr18:43,328,903...43,417,950
Ensembl chr18:43,328,824...43,417,952 		JBrowse link
G Hsdl2 hydroxysteroid dehydrogenase like 2 increases expression EXP tolcapone results in increased expression of HSDL2 mRNA CTD PMID:24136188 NCBI chr 5:74,443,933...74,479,104
Ensembl chr 5:74,443,872...74,479,839 		JBrowse link
G Iftap intraflagellar transport associated protein decreases expression EXP Tolcapone results in decreased expression of IFTAP mRNA CTD PMID:24136188 NCBI chr 3:87,812,068...87,906,517
Ensembl chr 3:87,817,408...87,906,547 		JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 increases expression EXP tolcapone results in increased expression of IGFBP1 mRNA CTD PMID:24136188 NCBI chr14:82,047,415...82,052,482
Ensembl chr14:82,047,415...82,052,482 		JBrowse link
G Il24 interleukin 24 decreases expression ISO Tolcapone results in decreased expression of IL24 mRNA CTD PMID:32816093 NCBI chr13:42,353,089...42,358,487
Ensembl chr13:42,353,090...42,358,487 		JBrowse link
G Ipo7 importin 7 affects binding EXP tolcapone binds to IPO7 protein CTD PMID:19783845 NCBI chr 1:164,062,702...164,102,938
Ensembl chr 1:164,062,702...164,102,938 		JBrowse link
G Itm2a integral membrane protein 2A affects binding EXP tolcapone binds to ITM2A protein CTD PMID:19783845 NCBI chr  X:72,486,383...72,492,344
Ensembl chr  X:72,486,381...72,492,363 		JBrowse link
G Jagn1 jagunal homolog 1 affects binding EXP tolcapone binds to JAGN1 protein CTD PMID:19783845 NCBI chr 4:146,591,577...146,596,287
Ensembl chr 4:146,591,510...146,596,288 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO tolcapone results in decreased activity of KCNH2 protein CTD PMID:24052561 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008 		JBrowse link
G Kgd4 alpha-ketoglutarate dehydrogenase subunit 4 decreases expression EXP Tolcapone results in decreased expression of KGD4 mRNA CTD PMID:24136188 NCBI chr 2:31,870,549...31,878,335
Ensembl chr 2:31,870,551...31,880,730 		JBrowse link
G Kng1 kininogen 1 increases expression EXP Tolcapone results in increased expression of KNG1 mRNA CTD PMID:24136188 NCBI chr11:77,812,757...77,835,555
Ensembl chr11:77,812,752...77,835,555 		JBrowse link
G Lage3 L antigen family, member 3 decreases expression EXP tolcapone results in decreased expression of LAGE3 mRNA CTD PMID:24136188 NCBI chr  X:152,138,209...152,139,632
Ensembl chr  X:152,138,218...152,139,632 		JBrowse link
G Lbp lipopolysaccharide binding protein increases expression EXP tolcapone results in increased expression of LBP mRNA CTD PMID:24136188 NCBI chr 3:146,953,889...146,981,032
Ensembl chr 3:146,954,015...146,981,586 		JBrowse link
G Lrrc59 leucine rich repeat containing 59 affects binding EXP tolcapone binds to LRRC59 protein CTD PMID:19783845 NCBI chr10:79,572,295...79,586,953
Ensembl chr10:79,572,317...79,602,533 		JBrowse link
G Lsm3 LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated decreases expression EXP tolcapone results in decreased expression of LSM3 mRNA CTD PMID:24136188 NCBI chr 4:124,021,023...124,027,269
Ensembl chr 4:124,021,023...124,027,269 		JBrowse link
G Lsm5 LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated decreases expression EXP tolcapone results in decreased expression of LSM5 mRNA CTD PMID:24136188 NCBI chr 4:85,951,073...85,954,289
Ensembl chr 6:104,652,477...104,654,165
Ensembl chr 4:104,652,477...104,654,165 		JBrowse link
G Lsm7 LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated decreases expression EXP tolcapone results in decreased expression of LSM7 mRNA CTD PMID:24136188 NCBI chr 7:8,856,698...8,859,113
Ensembl chr 7:8,856,489...8,859,119 		JBrowse link
G Magoh mago homolog, exon junction complex subunit decreases expression EXP tolcapone results in decreased expression of MAGOH mRNA CTD PMID:24136188 NCBI chr 5:122,639,268...122,646,650
Ensembl chr 5:122,639,308...122,646,617 		JBrowse link
G Masp1 MBL associated serine protease 1 increases expression EXP tolcapone results in increased expression of MASP1 mRNA CTD PMID:24136188 NCBI chr11:77,334,794...77,405,271
Ensembl chr11:77,334,859...77,402,974 		JBrowse link
G Matr3 matrin 3 decreases expression EXP tolcapone results in decreased expression of MATR3 mRNA CTD PMID:24136188 NCBI chr18:27,154,098...27,193,212
Ensembl chr18:27,163,714...27,193,166 		JBrowse link
G Mcee methylmalonyl CoA epimerase decreases expression EXP tolcapone results in decreased expression of MCEE mRNA CTD PMID:24136188 NCBI chr 1:117,964,576...117,987,779
Ensembl chr 1:117,964,576...117,988,484 		JBrowse link
G Mcts1 MCTS1, re-initiation and release factor decreases expression EXP tolcapone results in decreased expression of MCTS1 mRNA CTD PMID:24136188 NCBI chr  X:117,350,723...117,362,504
Ensembl chr  X:117,350,889...117,362,504 		JBrowse link
G Med21 mediator complex subunit 21 decreases expression EXP tolcapone results in decreased expression of MED21 mRNA CTD PMID:24136188 NCBI chr 4:179,560,509...179,583,811
Ensembl chr 4:179,560,579...179,567,548 		JBrowse link
G Med28 mediator complex subunit 28 decreases expression EXP tolcapone results in decreased expression of MED28 mRNA CTD PMID:24136188 NCBI chr14:65,594,785...65,603,583
Ensembl chr14:65,594,647...65,603,583 		JBrowse link
G Med31 mediator complex subunit 31 decreases expression EXP tolcapone results in decreased expression of MED31 mRNA CTD PMID:24136188 NCBI chr10:56,836,944...56,840,326
Ensembl chr10:56,836,944...56,840,326 		JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase increases expression ISO Tolcapone results in increased expression of MET mRNA CTD PMID:32816093 NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876 		JBrowse link
G Mettl5 methyltransferase 5, N6-adenosine decreases expression EXP tolcapone results in decreased expression of METTL5 mRNA CTD PMID:24136188 NCBI chr 3:54,625,790...54,638,066
Ensembl chr 3:54,625,793...54,638,039 		JBrowse link
G Mfsd5 major facilitator superfamily domain containing 5 decreases expression EXP tolcapone results in decreased expression of MFSD5 mRNA CTD PMID:24136188 NCBI chr 7:133,409,096...133,411,377
Ensembl chr 7:133,402,537...133,411,396 		JBrowse link
G Mgst1 microsomal glutathione S-transferase 1 affects binding EXP tolcapone binds to MGST1 protein CTD PMID:19783845 NCBI chr 4:171,029,666...171,044,893
Ensembl chr 4:171,029,630...171,044,892 		JBrowse link
G Mia3 MIA SH3 domain ER export factor 3 decreases expression EXP tolcapone results in decreased expression of MIA3 mRNA CTD PMID:24136188 NCBI chr13:94,970,421...95,012,071
Ensembl chr13:94,970,424...95,011,972 		JBrowse link
G Mkks MKKS centrosomal shuttling protein decreases expression EXP tolcapone results in decreased expression of MKKS mRNA CTD PMID:24136188 NCBI chr 3:124,201,877...124,221,142
Ensembl chr 3:124,201,877...124,220,162 		JBrowse link
G Mkrn1 makorin ring finger protein 1 decreases expression EXP tolcapone results in decreased expression of MKRN1 mRNA CTD PMID:24136188 NCBI chr 4:68,175,908...68,197,216
Ensembl chr 4:68,175,909...68,197,165 		JBrowse link
G Mmadhc metabolism of cobalamin associated D decreases expression EXP tolcapone results in decreased expression of MMADHC mRNA CTD PMID:24136188 NCBI chr 3:34,708,649...34,726,554
Ensembl chr 3:34,708,649...34,726,771 		JBrowse link
G Mrpl1 mitochondrial ribosomal protein L1 decreases expression EXP tolcapone results in decreased expression of MRPL1 mRNA CTD PMID:24136188 NCBI chr14:13,300,522...13,359,654
Ensembl chr14:13,300,522...13,359,721 		JBrowse link
G Mrpl13 mitochondrial ribosomal protein L13 decreases expression EXP tolcapone results in decreased expression of MRPL13 mRNA CTD PMID:24136188 NCBI chr 7:86,951,541...86,973,147
Ensembl chr 7:86,951,541...86,973,577 		JBrowse link
G Mrpl14 mitochondrial ribosomal protein L14 decreases expression EXP tolcapone results in decreased expression of MRPL14 mRNA CTD PMID:24136188 NCBI chr 9:15,302,840...15,315,195
Ensembl chr 9:15,302,427...15,315,267 		JBrowse link
G Mrpl18 mitochondrial ribosomal protein L18 decreases expression EXP tolcapone results in decreased expression of MRPL18 mRNA CTD PMID:24136188 NCBI chr 1:47,837,169...47,841,987
Ensembl chr 1:47,836,561...47,841,987 		JBrowse link
G Mrpl20 mitochondrial ribosomal protein L20 decreases expression EXP tolcapone results in decreased expression of MRPL20 mRNA CTD PMID:24136188 NCBI chr 5:166,408,962...166,413,492
Ensembl chr 5:166,408,962...166,413,492 		JBrowse link
G Mrpl22 mitochondrial ribosomal protein L22 decreases expression EXP tolcapone results in decreased expression of MRPL22 mRNA CTD PMID:24136188 NCBI chr10:42,345,446...42,355,779
Ensembl chr10:42,342,776...42,355,779 		JBrowse link
G Mrpl23 mitochondrial ribosomal protein L23 decreases expression EXP tolcapone results in decreased expression of MRPL23 mRNA CTD PMID:24136188 NCBI chr 1:197,687,452...197,695,222
Ensembl chr 1:197,687,347...197,695,222 		JBrowse link
G Mrpl30 mitochondrial ribosomal protein L30 decreases expression EXP tolcapone results in decreased expression of MRPL30 mRNA CTD PMID:24136188 NCBI chr 9:40,125,352...40,136,189
Ensembl chr 9:40,125,430...40,137,257 		JBrowse link
G Mrpl32 mitochondrial ribosomal protein L32 decreases expression EXP tolcapone results in decreased expression of MRPL32 mRNA CTD PMID:24136188 NCBI chr17:50,565,133...50,568,000
Ensembl chr17:50,565,055...50,568,010 		JBrowse link
G Mrpl36 mitochondrial ribosomal protein L36 decreases expression EXP tolcapone results in decreased expression of MRPL36 mRNA CTD PMID:24136188 NCBI chr 1:29,965,481...29,968,896
Ensembl chr 1:29,965,317...29,968,807 		JBrowse link
G Mrpl40 mitochondrial ribosomal protein L40 decreases expression EXP tolcapone results in decreased expression of MRPL40 mRNA CTD PMID:24136188 NCBI chr11:82,133,398...82,139,234
Ensembl chr11:82,133,398...82,139,233 		JBrowse link
G Mrpl53 mitochondrial ribosomal protein L53 decreases expression EXP tolcapone results in decreased expression of MRPL53 mRNA CTD PMID:24136188 NCBI chr 4:115,615,329...115,616,219 JBrowse link
G Mrps14 mitochondrial ribosomal protein S14 decreases expression EXP tolcapone results in decreased expression of MRPS14 mRNA CTD PMID:24136188 NCBI chr13:72,429,168...72,434,915
Ensembl chr13:72,408,558...72,434,915 		JBrowse link
G Mrps18c mitochondrial ribosomal protein S18C decreases expression EXP tolcapone results in decreased expression of MRPS18C mRNA CTD PMID:24136188 NCBI chr14:8,812,301...8,818,538
Ensembl chr14:8,791,330...8,818,516 		JBrowse link
G Mrps24 mitochondrial ribosomal protein S24 decreases expression EXP tolcapone results in decreased expression of MRPS24 mRNA CTD PMID:24136188 NCBI chr14:80,584,671...80,588,801
Ensembl chr14:80,584,673...80,588,871 		JBrowse link
G Mrps33 mitochondrial ribosomal protein S33 decreases expression EXP tolcapone results in decreased expression of MRPS33 mRNA CTD PMID:24136188 NCBI chr 4:68,596,729...68,605,547
Ensembl chr 4:68,596,729...68,605,428 		JBrowse link
G Mtap methylthioadenosine phosphorylase affects binding EXP tolcapone binds to MTAP protein CTD PMID:19783845 NCBI chr 5:103,874,460...103,920,684
Ensembl chr 5:103,873,020...103,939,406 		JBrowse link
G Mttp microsomal triglyceride transfer protein increases expression ISO tolcapone results in increased expression of MTTP protein CTD PMID:29688484 NCBI chr 2:226,613,090...226,654,239
Ensembl chr 2:226,613,090...226,654,239 		JBrowse link
G Mvk mevalonate kinase increases expression EXP tolcapone results in increased expression of MVK mRNA CTD PMID:24136188 NCBI chr12:42,141,391...42,158,893
Ensembl chr12:42,141,384...42,158,882 		JBrowse link
G Naa20 N(alpha)-acetyltransferase 20, NatB catalytic subunit decreases expression EXP tolcapone results in decreased expression of NAA20 mRNA CTD PMID:24136188 NCBI chr 3:133,322,036...133,336,843
Ensembl chr 3:133,322,064...133,337,009 		JBrowse link
G Nat10 N-acetyltransferase 10 affects binding EXP tolcapone binds to NAT10 protein CTD PMID:19783845 NCBI chr 3:90,111,643...90,149,891
Ensembl chr 3:90,111,645...90,149,927 		JBrowse link
G Ndufa1 NADH:ubiquinone oxidoreductase subunit A1 decreases expression EXP tolcapone results in decreased expression of NDUFA1 mRNA CTD PMID:24136188 NCBI chr  X:116,424,223...116,427,875
Ensembl chr  X:116,424,223...116,428,633 		JBrowse link
G Ndufa2 NADH:ubiquinone oxidoreductase subunit A2 decreases expression EXP tolcapone results in decreased expression of NDUFA2 mRNA CTD PMID:24136188 NCBI chr18:28,355,774...28,357,863
Ensembl chr18:28,355,774...28,358,076 		JBrowse link
G Ndufa6 NADH:ubiquinone oxidoreductase subunit A6 decreases expression EXP tolcapone results in decreased expression of NDUFA6 mRNA CTD PMID:24136188 NCBI chr 7:113,866,382...113,870,239
Ensembl chr 7:113,866,382...113,870,239 		JBrowse link
G Ndufa7 NADH:ubiquinone oxidoreductase subunit A7 decreases expression EXP tolcapone results in decreased expression of NDUFA7 mRNA CTD PMID:24136188 NCBI chr 7:14,609,283...14,622,064
Ensembl chr 7:14,609,146...14,631,976 		JBrowse link
G Ndufa9 NADH:ubiquinone oxidoreductase subunit A9 affects binding EXP tolcapone binds to NDUFA9 protein CTD PMID:19783845 NCBI chr 4:159,659,242...159,688,034
Ensembl chr 4:159,659,242...159,688,018 		JBrowse link
G Ndufb6 NADH:ubiquinone oxidoreductase subunit B6 decreases expression EXP tolcapone results in decreased expression of NDUFB6 mRNA CTD PMID:24136188 NCBI chr 5:55,400,543...55,410,110
Ensembl chr 5:55,400,543...55,410,181 		JBrowse link
G Ndufc2 NADH:ubiquinone oxidoreductase subunit C2 decreases expression EXP tolcapone results in decreased expression of NDUFC2 mRNA CTD PMID:24136188 NCBI chr 1:151,711,965...151,718,188
Ensembl chr 1:151,711,901...151,718,189 		JBrowse link
G Ndufs4 NADH:ubiquinone oxidoreductase subunit S4 decreases expression EXP tolcapone results in decreased expression of NDUFS4 mRNA CTD PMID:24136188 NCBI chr 2:45,951,327...46,061,829
Ensembl chr 2:45,951,313...46,061,846 		JBrowse link
G Ndufs5 NADH:ubiquinone oxidoreductase subunit S5 decreases expression EXP tolcapone results in decreased expression of NDUFS5 mRNA CTD PMID:24136188 NCBI chr 5:135,974,029...135,979,705
Ensembl chr 5:135,974,034...135,979,603
Ensembl chr14:135,974,034...135,979,603
Ensembl chr 2:135,974,034...135,979,603 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 decreases expression ISO tolcapone results in decreased expression of NFE2L2 mRNA CTD PMID:28526448 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nipsnap1 nipsnap homolog 1 affects binding EXP tolcapone binds to NIPSNAP1 protein CTD PMID:19783845 NCBI chr14:79,734,234...79,758,101
Ensembl chr14:79,734,209...79,758,098 		JBrowse link
G Nipsnap2 nipsnap homolog 2 affects binding EXP tolcapone binds to NIPSNAP2 protein CTD PMID:19783845 NCBI chr12:26,906,068...26,944,201
Ensembl chr12:26,911,723...26,944,166 		JBrowse link
G Nme3 NME/NM23 nucleoside diphosphate kinase 3 decreases expression EXP tolcapone results in decreased expression of NME3 mRNA CTD PMID:24136188 NCBI chr10:13,917,309...13,918,415
Ensembl chr10:13,917,403...13,918,359 		JBrowse link
G Nop56 NOP56 ribonucleoprotein affects binding EXP tolcapone binds to NOP56 protein CTD PMID:19783845 NCBI chr 3:117,476,963...117,481,847
Ensembl chr 3:117,477,053...117,481,841 		JBrowse link
G Nphp1 nephrocystin 1 decreases expression EXP tolcapone results in decreased expression of NPHP1 mRNA CTD PMID:24136188 NCBI chr 3:114,960,650...115,016,234
Ensembl chr 3:114,960,650...115,016,234 		JBrowse link
G Nploc4 NPL4 homolog, ubiquitin recognition factor increases expression EXP tolcapone results in increased expression of NPLOC4 mRNA CTD PMID:24136188 NCBI chr10:105,654,395...105,709,958
Ensembl chr10:105,654,812...105,709,913 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 decreases expression EXP tolcapone results in decreased expression of NR3C1 mRNA CTD PMID:24136188 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375 		JBrowse link
G Nupr2 nuclear protein 2, transcriptional regulator decreases expression EXP tolcapone results in decreased expression of NUPR2 mRNA CTD PMID:24136188 NCBI chr12:26,800,123...26,803,228
Ensembl chr12:26,799,800...26,803,304 		JBrowse link
G P4ha1 prolyl 4-hydroxylase subunit alpha 1 affects binding EXP tolcapone binds to P4HA1 protein CTD PMID:19783845 NCBI chr20:27,302,046...27,352,098
Ensembl chr20:27,302,141...27,352,786 		JBrowse link
G Pc pyruvate carboxylase affects binding EXP tolcapone binds to PC protein CTD PMID:19783845 NCBI chr 1:201,799,374...201,898,412
Ensembl chr 1:201,804,267...201,898,380 		JBrowse link
G Pcna proliferating cell nuclear antigen decreases expression EXP tolcapone results in decreased expression of PCNA mRNA CTD PMID:24136188 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995 		JBrowse link
G Pcyt1a phosphate cytidylyltransferase 1A, choline affects binding EXP tolcapone binds to PCYT1A protein CTD PMID:19783845 NCBI chr11:68,313,860...68,357,828
Ensembl chr11:68,313,882...68,357,357 		JBrowse link
G Pdzd11 PDZ domain containing 11 decreases expression EXP tolcapone results in decreased expression of PDZD11 mRNA CTD PMID:24136188 NCBI chr  X:65,718,689...65,721,742
Ensembl chr  X:65,704,067...65,721,642 		JBrowse link
G Pfdn1 prefoldin subunit 1 decreases expression EXP tolcapone results in decreased expression of PFDN1 mRNA CTD PMID:24136188 NCBI chr18:28,014,145...28,067,148
Ensembl chr18:28,014,145...28,067,064 		JBrowse link
G Pfdn5 prefoldin subunit 5 decreases expression EXP tolcapone results in decreased expression of PFDN5 mRNA CTD PMID:24136188 NCBI chr 7:133,451,778...133,456,516
Ensembl chr 7:133,451,453...133,456,516 		JBrowse link
G Pgm1 phosphoglucomutase 1 increases expression EXP tolcapone results in increased expression of PGM1 mRNA CTD PMID:24136188 NCBI chr 5:114,595,298...114,654,728
Ensembl chr 5:114,595,293...114,654,728 		JBrowse link
G Pgr progesterone receptor multiple interactions ISO tolcapone binds to and results in decreased activity of PGR protein CTD PMID:25752796 NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344 		JBrowse link
G Pigp phosphatidylinositol glycan anchor biosynthesis, class P decreases expression EXP tolcapone results in decreased expression of PIGP mRNA CTD PMID:24136188 NCBI chr11:33,682,943...33,689,111
Ensembl chr11:33,682,948...33,689,321 		JBrowse link
G Pigs phosphatidylinositol glycan anchor biosynthesis, class S affects binding EXP tolcapone binds to PIGS protein CTD PMID:19783845 NCBI chr10:63,222,611...63,237,190
Ensembl chr10:63,222,572...63,237,187 		JBrowse link
G Pin4 peptidylprolyl cis/trans isomerase, NIMA-interacting 4 decreases expression EXP tolcapone results in decreased expression of PIN4 mRNA CTD PMID:24136188 NCBI chr  X:67,232,066...67,238,709
Ensembl chr  X:67,232,081...67,238,702 		JBrowse link
G Plin2 perilipin 2 affects binding EXP tolcapone binds to PLIN2 protein CTD PMID:19783845 NCBI chr 5:101,156,648...101,211,738
Ensembl chr 5:101,154,411...101,242,319 		JBrowse link
G Plin3 perilipin 3 affects binding EXP tolcapone binds to PLIN3 protein CTD PMID:19783845 NCBI chr 9:1,111,178...1,123,057
Ensembl chr 9:1,102,366...1,123,147 		JBrowse link
G Pnpla2 patatin-like phospholipase domain containing 2 increases expression EXP tolcapone results in increased expression of PNPLA2 mRNA CTD PMID:24136188 NCBI chr 1:196,552,723...196,557,805
Ensembl chr 1:196,552,723...196,557,805 		JBrowse link
G Polr1h RNA polymerase I subunit H decreases expression EXP Tolcapone results in decreased expression of POLR1H mRNA CTD PMID:24136188 NCBI chr20:1,594,936...1,598,854
Ensembl chr20:1,594,936...1,598,854 		JBrowse link
G Polr2g RNA polymerase II subunit G decreases expression EXP tolcapone results in decreased expression of POLR2G mRNA CTD PMID:24136188 NCBI chr 1:205,689,160...205,692,537
Ensembl chr 1:205,689,160...205,692,686 		JBrowse link
G Prpf8 pre-mRNA processing factor 8 affects binding EXP tolcapone binds to PRPF8 protein CTD PMID:19783845 NCBI chr10:60,331,494...60,354,606
Ensembl chr10:60,331,494...60,354,606 		JBrowse link
G Prxl2a peroxiredoxin like 2A affects binding EXP tolcapone binds to PRXL2A protein CTD PMID:19783845 NCBI chr16:16,866,601...16,886,378
Ensembl chr16:16,866,603...16,886,433 		JBrowse link
G Psmc5 proteasome 26S subunit, ATPase 5 affects binding EXP tolcapone binds to PSMC5 protein CTD PMID:19783845 NCBI chr10:91,187,763...91,193,697
Ensembl chr10:91,187,743...91,213,135 		JBrowse link
G Psme2 proteasome activator subunit 2 affects binding EXP tolcapone binds to PSME2 protein CTD PMID:19783845 NCBI chr15:29,078,495...29,082,794
Ensembl chr15:29,078,500...29,082,946 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression ISO Tolcapone results in increased expression of PTGS2 mRNA CTD PMID:32816093 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Ptrh2 peptidyl-tRNA hydrolase 2 affects binding EXP tolcapone binds to PTRH2 protein CTD PMID:19783845 NCBI chr10:71,505,113...71,515,297
Ensembl chr10:71,504,956...71,515,398 		JBrowse link
G Ramac RNA guanine-7 methyltransferase activating subunit decreases expression EXP tolcapone results in decreased expression of RAMAC mRNA CTD PMID:24136188 NCBI chr 1:135,708,529...135,714,417
Ensembl chr 1:135,708,535...135,722,151 		JBrowse link
G Ran RAN, member RAS oncogene family affects binding EXP tolcapone binds to RAN protein CTD PMID:19783845 NCBI chr12:27,674,049...27,678,598
Ensembl chr12:27,674,050...27,678,276 		JBrowse link
G Rap1a RAP1A, member of RAS oncogene family decreases expression EXP tolcapone results in decreased expression of RAP1A mRNA CTD PMID:24136188 NCBI chr 2:193,208,631...193,286,513
Ensembl chr 2:193,208,635...193,286,501 		JBrowse link
G Rbis ribosomal biogenesis factor decreases expression EXP Tolcapone results in decreased expression of RBIS mRNA CTD PMID:24136188 NCBI chr 2:86,981,314...86,997,352
Ensembl chr 2:86,991,315...87,041,339 		JBrowse link
G Rbm8a RNA binding motif protein 8A decreases expression EXP tolcapone results in decreased expression of RBM8A mRNA CTD PMID:24136188 NCBI chr 2:184,165,189...184,167,959
Ensembl chr 2:184,165,193...184,167,959 		JBrowse link
G Rbp1 retinol binding protein 1 decreases expression EXP tolcapone results in decreased expression of RBP1 mRNA CTD PMID:24136188 NCBI chr 8:99,025,218...99,046,740
Ensembl chr 8:99,025,206...99,046,743 		JBrowse link
G Reep6 receptor accessory protein 6 affects binding EXP tolcapone binds to REEP6 protein CTD PMID:19783845 NCBI chr 7:9,373,927...9,380,845
Ensembl chr 7:9,373,927...9,380,597 		JBrowse link
G RGD1311745 similar to RIKEN cDNA 1110059G10 decreases expression EXP tolcapone results in decreased expression of RGD1311745 mRNA CTD PMID:24136188 NCBI chr 8:122,598,363...122,609,127
Ensembl chr 8:122,598,401...122,609,168 		JBrowse link
G Rnf7 ring finger protein 7 decreases expression EXP tolcapone results in decreased expression of RNF7 mRNA CTD PMID:24136188 NCBI chr 8:97,038,845...97,048,080
Ensembl chr 8:97,038,840...97,047,824 		JBrowse link
G Rnls renalase, FAD-dependent amine oxidase decreases expression EXP tolcapone results in decreased expression of RNLS mRNA CTD PMID:24136188 NCBI chr 1:231,037,481...231,309,855
Ensembl chr 1:231,037,486...231,309,823 		JBrowse link
G Romo1 reactive oxygen species modulator 1 decreases expression EXP tolcapone results in decreased expression of ROMO1 mRNA CTD PMID:24136188 NCBI chr 3:144,659,709...144,661,310
Ensembl chr 3:144,659,826...144,661,310 		JBrowse link
G Rpa3 replication protein A3 decreases expression EXP tolcapone results in decreased expression of RPA3 mRNA CTD PMID:24136188 NCBI chr 4:36,304,649...36,307,755
Ensembl chr 4:36,304,651...36,307,709 		JBrowse link
G Rpl10a ribosomal protein L10A affects binding EXP tolcapone binds to RPL10A protein CTD PMID:19783845 NCBI chr20:6,388,800...6,391,358
Ensembl chr20:6,385,823...6,391,357 		JBrowse link
G Rpl15 ribosomal protein L15 affects binding EXP tolcapone binds to RPL15 protein CTD PMID:19783845 NCBI chr15:7,503,883...7,507,166
Ensembl chr15:7,503,883...7,507,165 		JBrowse link
G Rpl18a ribosomal protein L18A affects binding EXP tolcapone binds to RPL18A protein CTD PMID:19783845 NCBI chr16:18,542,555...18,544,578
Ensembl chr16:18,542,566...18,545,546 		JBrowse link
G Rpl22 ribosomal protein L22 affects binding EXP tolcapone binds to RPL22 protein CTD PMID:19783845 NCBI chr 5:162,835,241...162,843,394
Ensembl chr 5:162,833,740...162,843,368
Ensembl chr 7:162,833,740...162,843,368
Ensembl chr 4:162,833,740...162,843,368 		JBrowse link
G Rpl22l1 ribosomal protein L22 like 1 decreases expression EXP tolcapone results in decreased expression of RPL22L1 mRNA CTD PMID:24136188 NCBI chr 2:111,754,687...111,756,623
Ensembl chr 2:111,754,687...111,756,625 		JBrowse link
G Rpl23 ribosomal protein L23 affects binding EXP tolcapone binds to RPL23 protein CTD PMID:19783845 NCBI chr10:82,771,878...82,775,840
Ensembl chr10:82,771,538...82,775,870 		JBrowse link
G Rpl35a ribosomal protein L35A decreases expression EXP tolcapone results in decreased expression of RPL35A mRNA CTD PMID:24136188 NCBI chr11:67,726,031...67,729,953
Ensembl chr11:67,726,032...67,729,942
Ensembl chr 5:67,726,032...67,729,942 		JBrowse link
G Rpl36a ribosomal protein L36A decreases expression EXP tolcapone results in decreased expression of RPL36A mRNA CTD PMID:24136188 NCBI chr  X:97,766,179...97,768,892
Ensembl chr  X:97,766,179...97,768,892 		JBrowse link
G Rpl41 ribosomal protein L41 decreases expression EXP tolcapone results in decreased expression of RPL41 mRNA CTD PMID:24136188 NCBI chr 7:977,885...978,965 JBrowse link
G Rpl7a ribosomal protein L7A affects binding EXP tolcapone binds to RPL7A protein CTD PMID:19783845 NCBI chr 3:10,239,026...10,241,703
Ensembl chr 3:10,239,001...10,241,716 		JBrowse link
G Rpl7l1 ribosomal protein L7-like 1 affects binding EXP tolcapone binds to RPL7L1 protein CTD PMID:19783845 NCBI chr 9:14,198,101...14,206,119
Ensembl chr 9:14,198,092...14,206,110 		JBrowse link
G Rpl9 ribosomal protein L9 decreases expression EXP tolcapone results in decreased expression of RPL9 mRNA CTD PMID:24136188 NCBI chr14:42,893,945...42,897,140
Ensembl chr14:42,893,942...42,897,136
Ensembl chr 3:42,893,942...42,897,136 		JBrowse link
G Rpp21 ribonuclease P/MRP subunit p21 decreases expression EXP tolcapone results in decreased expression of RPP21 mRNA CTD PMID:24136188 NCBI chr20:2,018,170...2,020,100
Ensembl chr20:2,018,147...2,020,106 		JBrowse link
G Rps11 ribosomal protein S11 affects binding EXP tolcapone binds to RPS11 protein CTD PMID:19783845 NCBI chr 1:95,605,690...95,607,798
Ensembl chr 1:95,605,692...95,607,874 		JBrowse link
G Rps14 ribosomal protein S14 affects binding EXP tolcapone binds to RPS14 protein CTD PMID:19783845 NCBI chr18:54,227,854...54,232,638
Ensembl chr18:54,227,854...54,233,166 		JBrowse link
G Rps15a ribosomal protein S15a decreases expression EXP tolcapone results in decreased expression of RPS15A mRNA CTD PMID:24136188 NCBI chr 1:172,420,151...172,427,021
Ensembl chr 1:172,419,761...172,426,995 		JBrowse link
G Rps20 ribosomal protein S20 affects binding EXP tolcapone binds to RPS20 protein CTD PMID:19783845 NCBI chr 5:16,819,095...16,820,476
Ensembl chr 5:16,819,304...16,820,475
Ensembl chr 9:16,819,304...16,820,475
Ensembl chr 3:16,819,304...16,820,475 		JBrowse link
G Rps21-ps1 ribosomal protein S21, pseudogene 1 decreases expression EXP tolcapone results in decreased expression of RPS21 mRNA CTD PMID:24136188 NCBI chr 5:153,387,133...153,387,476
Ensembl chr 5:153,387,176...153,387,427 		JBrowse link
G Rps24 ribosomal protein S24 decreases expression EXP tolcapone results in decreased expression of RPS24 mRNA CTD PMID:24136188 NCBI chr16:89,538...94,267
Ensembl chr16:89,604...94,279 		JBrowse link
G Rps25 ribosomal protein s25 decreases expression EXP tolcapone results in decreased expression of RPS25 mRNA CTD PMID:24136188 NCBI chr 8:44,733,623...44,735,999
Ensembl chr 8:44,733,029...44,737,271 		JBrowse link
G Rps27 ribosomal protein S27 decreases expression EXP tolcapone results in decreased expression of RPS27 mRNA CTD PMID:24136188 NCBI chr 2:175,665,858...175,666,963
Ensembl chr 2:175,665,853...175,666,964 		JBrowse link
G Rps27a ribosomal protein S27a affects binding EXP tolcapone binds to RPS27A protein CTD PMID:19783845 NCBI chr14:103,285,734...103,288,011
Ensembl chr14:103,285,734...103,288,011
Ensembl chr 5:103,285,734...103,288,011 		JBrowse link
G S100a10 S100 calcium binding protein A10 decreases expression EXP tolcapone results in decreased expression of S100A10 mRNA CTD PMID:24136188 NCBI chr 2:179,221,012...179,229,659
Ensembl chr 2:179,220,887...179,229,661 		JBrowse link
G Sc5d sterol-C5-desaturase increases expression EXP tolcapone results in increased expression of SC5D mRNA CTD PMID:24136188 NCBI chr 8:42,629,649...42,641,257
Ensembl chr 8:42,632,672...42,641,273 		JBrowse link
G Scd stearoyl-CoA desaturase affects binding
decreases expression		 EXP tolcapone binds to SCD protein
tolcapone results in decreased expression of SCD1 mRNA		 CTD PMID:19783845 PMID:24136188 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562 		JBrowse link
G Sdha succinate dehydrogenase complex flavoprotein subunit A affects binding EXP tolcapone binds to SDHA protein CTD PMID:19783845 NCBI chr 1:28,935,965...28,960,936
Ensembl chr 1:28,940,164...28,961,535 		JBrowse link
G Sdhb succinate dehydrogenase complex iron sulfur subunit B affects binding EXP tolcapone binds to SDHB protein CTD PMID:19783845 NCBI chr 5:153,264,906...153,285,570
Ensembl chr 5:153,264,899...153,314,293 		JBrowse link
G Sec11c SEC11 homolog C, signal peptidase complex subunit affects binding EXP tolcapone binds to SEC11C protein CTD PMID:19783845 NCBI chr18:59,320,932...59,337,272
Ensembl chr18:59,320,884...59,337,364 		JBrowse link
G Sec31a SEC31 homolog A, COPII coat complex component affects binding EXP tolcapone binds to SEC31A protein CTD PMID:19783845 NCBI chr14:9,214,324...9,269,281
Ensembl chr14:9,214,349...9,269,273 		JBrowse link
G Serbp1 Serpine1 mRNA binding protein 1 affects binding EXP tolcapone binds to SERBP1 protein CTD PMID:19783845 NCBI chr 4:96,401,587...96,421,816
Ensembl chr 4:96,401,477...96,421,813 		JBrowse link
G Sf3b6 splicing factor 3B, subunit 6 affects binding EXP tolcapone binds to SF3B6 protein CTD PMID:19783845 NCBI chr 6:27,826,044...27,835,086
Ensembl chr 6:27,826,029...27,835,156 		JBrowse link
G Sfxn1 sideroflexin 1 affects binding EXP tolcapone binds to SFXN1 protein CTD PMID:19783845 NCBI chr17:10,486,250...10,522,640
Ensembl chr17:10,486,271...10,522,529 		JBrowse link
G Sik3 SIK family kinase 3 increases expression EXP tolcapone results in increased expression of SIK3 mRNA CTD PMID:24136188 NCBI chr 8:46,312,253...46,522,444
Ensembl chr 8:46,311,989...46,522,444 		JBrowse link
G Slc1a5 solute carrier family 1 member 5 affects binding EXP tolcapone binds to SLC1A5 protein CTD PMID:19783845 NCBI chr 1:77,456,849...77,470,952
Ensembl chr 1:77,456,694...77,470,952 		JBrowse link
G Slc25a1 solute carrier family 25 member 1 affects binding EXP tolcapone binds to SLC25A1 protein CTD PMID:19783845 NCBI chr11:83,055,764...83,058,781
Ensembl chr11:83,055,748...83,058,781 		JBrowse link
G Slc25a13 solute carrier family 25 member 13 affects binding EXP tolcapone binds to SLC25A13 protein CTD PMID:19783845 NCBI chr 4:34,179,224...34,361,912
Ensembl chr 4:34,179,224...34,361,902 		JBrowse link
G Slc25a4 solute carrier family 25 member 4 affects binding EXP tolcapone binds to SLC25A4 protein CTD PMID:19783845 NCBI chr16:46,072,935...46,076,730
Ensembl chr16:46,072,939...46,076,733 		JBrowse link
G Slc25a5 solute carrier family 25 member 5 affects binding EXP tolcapone binds to SLC25A5 protein CTD PMID:19783845 NCBI chr  X:116,031,896...116,034,963
Ensembl chr  X:116,031,803...116,034,967 		JBrowse link
G Slc25a6 solute carrier family 25 member 6 affects binding EXP tolcapone binds to SLC25A6 protein CTD PMID:19783845 NCBI chr18:68,571,222...68,572,461
Ensembl chr18:68,571,300...68,572,199 		JBrowse link
G Slc39a7 solute carrier family 39 member 7 affects binding EXP tolcapone binds to SLC39A7 protein CTD PMID:19783845 NCBI chr20:4,823,166...4,826,538
Ensembl chr20:4,822,012...4,826,537 		JBrowse link
G Slc7a11 solute carrier family 7 member 11 decreases expression ISO Tolcapone results in decreased expression of SLC7A11 mRNA CTD PMID:32816093 NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536 		JBrowse link
G Slpi secretory leukocyte peptidase inhibitor decreases expression ISO Tolcapone results in decreased expression of SLPI mRNA CTD PMID:32816093 NCBI chr 3:153,082,208...153,084,457
Ensembl chr 3:153,082,369...153,084,453 		JBrowse link
G Smim26 small integral membrane protein 26 decreases expression EXP tolcapone results in decreased expression of SMIM26 mRNA CTD PMID:24136188 NCBI chr 3:131,990,147...131,991,779
Ensembl chr 3:131,990,291...131,992,132 		JBrowse link
G Snapin SNAP-associated protein decreases expression EXP tolcapone results in decreased expression of SNAPIN mRNA CTD PMID:24136188 NCBI chr 2:175,971,575...175,974,164
Ensembl chr 2:175,971,257...175,974,231 		JBrowse link
G Snca synuclein alpha multiple interactions ISO tolcapone inhibits the reaction [SNCA protein binds to SNCA protein] CTD PMID:20150427 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262 		JBrowse link
G Snrnp27 small nuclear ribonucleoprotein U4/U6.U5 subunit 27 decreases expression EXP Tolcapone results in decreased expression of SNRNP27 mRNA CTD PMID:24136188 NCBI chr 4:119,123,676...119,133,234
Ensembl chr 4:119,121,877...119,133,234 		JBrowse link
G Snrpb2 small nuclear ribonucleoprotein polypeptide B2 decreases expression EXP tolcapone results in decreased expression of SNRPB2 mRNA CTD PMID:24136188 NCBI chr 3:130,399,239...130,408,821
Ensembl chr 3:130,399,248...130,408,812 		JBrowse link
G Snrpd3 small nuclear ribonucleoprotein D3 polypeptide decreases expression EXP tolcapone results in decreased expression of SNRPD3 mRNA CTD PMID:24136188 NCBI chr20:13,130,112...13,145,947
Ensembl chr20:13,130,119...13,145,978 		JBrowse link
G Snrpe small nuclear ribonucleoprotein polypeptide E decreases expression EXP tolcapone results in decreased expression of SNRPE mRNA CTD PMID:24136188 NCBI chr13:45,050,986...45,057,231
Ensembl chr13:45,050,986...45,057,310
Ensembl chr 8:45,050,986...45,057,310 		JBrowse link
G Snrpf small nuclear ribonucleoprotein polypeptide F decreases expression EXP tolcapone results in decreased expression of SNRPF mRNA CTD PMID:24136188 NCBI chr 7:28,130,427...28,137,129
Ensembl chr 7:28,130,427...28,137,129 		JBrowse link
G Snrpg small nuclear ribonucleoprotein polypeptide G decreases expression EXP tolcapone results in decreased expression of SNRPG mRNA CTD PMID:24136188 NCBI chr 4:118,812,278...118,819,827
Ensembl chr 4:118,812,252...118,819,826 		JBrowse link
G Sod1 superoxide dismutase 1 decreases expression ISO tolcapone results in decreased expression of SOD1 mRNA CTD PMID:28526448 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Sod2 superoxide dismutase 2 decreases expression ISO tolcapone results in decreased expression of SOD2 mRNA CTD PMID:28526448 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Srp14 signal recognition particle 14 decreases expression EXP tolcapone results in decreased expression of SRP14 mRNA CTD PMID:24136188 NCBI chr 3:105,442,184...105,445,875
Ensembl chr 3:105,442,198...105,445,859 		JBrowse link
G Srprb SRP receptor subunit beta affects binding EXP tolcapone binds to SRPRB protein CTD PMID:19783845 NCBI chr 8:103,768,685...103,782,632 JBrowse link
G Ss18l2 SS18 like 2 decreases expression EXP tolcapone results in decreased expression of SS18L2 mRNA CTD PMID:24136188 NCBI chr 8:121,375,263...121,377,877
Ensembl chr 8:121,375,308...121,377,877 		JBrowse link
G Ssr1 signal sequence receptor subunit 1 affects binding EXP tolcapone binds to SSR1 protein CTD PMID:19783845 NCBI chr17:26,833,720...26,861,821
Ensembl chr17:26,833,741...26,861,821 		JBrowse link
G Stac3 SH3 and cysteine rich domain 3 decreases expression EXP tolcapone results in decreased expression of STAC3 mRNA CTD PMID:24136188 NCBI chr 7:63,343,078...63,350,590
Ensembl chr 7:63,343,186...63,350,589 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 increases expression EXP tolcapone results in increased expression of STAT3 mRNA CTD PMID:24136188 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 affects binding EXP tolcapone binds to SULT2A1 protein CTD PMID:19783845 NCBI chr 1:75,451,178...75,508,113
Ensembl chr 1:74,911,100...75,508,134 		JBrowse link
G Taf9 TATA-box binding protein associated factor 9 decreases expression EXP tolcapone results in decreased expression of TAF9 mRNA CTD PMID:24136188 NCBI chr 2:31,794,316...31,798,324
Ensembl chr 2:31,794,142...31,798,769 		JBrowse link
G Tbca tubulin folding cofactor A decreases expression EXP tolcapone results in decreased expression of TBCA mRNA CTD PMID:24136188 NCBI chr 2:26,011,714...26,065,909
Ensembl chr 2:26,011,795...26,065,907 		JBrowse link
G Tceal8 transcription elongation factor A like 8 decreases expression EXP tolcapone results in decreased expression of TCEAL8 mRNA CTD PMID:24136188 NCBI chr  X:99,171,307...99,173,377
Ensembl chr  X:99,171,177...99,173,710 		JBrowse link
G Tfr2 transferrin receptor 2 increases expression EXP tolcapone results in increased expression of TFR2 mRNA CTD PMID:24136188 NCBI chr12:19,107,673...19,124,622
Ensembl chr12:19,107,673...19,124,591 		JBrowse link
G Timm10 translocase of inner mitochondrial membrane 10 decreases expression EXP tolcapone results in decreased expression of TIMM10 mRNA CTD PMID:24136188 NCBI chr 3:69,908,397...69,911,943
Ensembl chr 3:69,908,456...69,911,940 		JBrowse link
G Timm44 translocase of inner mitochondrial membrane 44 affects binding EXP tolcapone binds to TIMM44 protein CTD PMID:19783845 NCBI chr12:2,612,581...2,629,374
Ensembl chr12:2,612,581...2,629,351 		JBrowse link
G Timm8b translocase of inner mitochondrial membrane 8 homolog B decreases expression EXP tolcapone results in decreased expression of TIMM8B mRNA CTD PMID:24136188 NCBI chr 8:50,954,350...50,955,730
Ensembl chr 8:50,954,342...50,955,729 		JBrowse link
G Tk2 thymidine kinase 2 affects binding EXP tolcapone binds to TK2 protein CTD PMID:19783845 NCBI chr19:708,859...731,786
Ensembl chr19:708,891...730,924 		JBrowse link
G Tm2d1 TM2 domain containing 1 decreases expression EXP tolcapone results in decreased expression of TM2D1 mRNA CTD PMID:24136188 NCBI chr 5:113,020,793...113,062,134
Ensembl chr 5:113,020,760...113,050,933 		JBrowse link
G Tmed10 transmembrane p24 trafficking protein 10 affects binding EXP tolcapone binds to TMED10 protein CTD PMID:19783845 NCBI chr 6:104,991,843...105,026,705
Ensembl chr 6:104,991,838...105,026,753 		JBrowse link
G Tmed4 transmembrane p24 trafficking protein 4 affects binding EXP tolcapone binds to TMED4 protein CTD PMID:19783845 NCBI chr14:81,125,049...81,129,646
Ensembl chr14:81,125,053...81,129,631 		JBrowse link
G Tmed9 transmembrane p24 trafficking protein 9 affects binding EXP tolcapone binds to TMED9 protein CTD PMID:19783845 NCBI chr17:9,029,646...9,034,160
Ensembl chr17:9,029,646...9,034,176 		JBrowse link
G Tmem126a transmembrane protein 126A decreases expression EXP tolcapone results in decreased expression of TMEM126A mRNA CTD PMID:24136188 NCBI chr 1:144,424,481...144,430,730
Ensembl chr 1:144,422,703...144,430,628 		JBrowse link
G Tmem126b transmembrane protein 126B decreases expression EXP tolcapone results in decreased expression of TMEM126B mRNA CTD PMID:24136188 NCBI chr 1:144,437,142...144,451,508
Ensembl chr 1:144,437,145...144,451,435 		JBrowse link
G Tmem128 transmembrane protein 128 decreases expression EXP tolcapone results in decreased expression of TMEM128 mRNA CTD PMID:24136188 NCBI chr14:72,539,530...72,548,623
Ensembl chr14:72,539,532...72,548,550 		JBrowse link
G Tmem203 transmembrane protein 203 decreases expression EXP tolcapone results in decreased expression of TMEM203 mRNA CTD PMID:24136188 NCBI chr 3:8,070,904...8,071,732
Ensembl chr 3:8,070,914...8,071,867 		JBrowse link
G Tmem238 transmembrane protein 238 decreases expression EXP tolcapone results in decreased expression of TMEM238 mRNA CTD PMID:24136188 NCBI chr 1:69,057,083...69,062,477
Ensembl chr 1:69,056,805...69,076,133 		JBrowse link
G Tmem256 transmembrane protein 256 decreases expression EXP tolcapone results in decreased expression of TMEM256 mRNA CTD PMID:24136188 NCBI chr10:54,559,030...54,560,146
Ensembl chr10:54,555,360...54,560,120 		JBrowse link
G Tmsb4x thymosin beta 4, X-linked decreases expression EXP tolcapone results in decreased expression of TMSB4X mRNA CTD PMID:24136188 NCBI chr  X:27,144,666...27,146,667
Ensembl chr  X:27,128,610...27,146,667 		JBrowse link
G Tnfaip8 TNF alpha induced protein 8 affects binding EXP tolcapone binds to TNFAIP8 protein CTD PMID:19783845 NCBI chr18:43,183,854...43,299,512
Ensembl chr18:43,183,916...43,299,517 		JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A increases expression EXP tolcapone results in increased expression of TNFRSF1A mRNA CTD PMID:24136188 NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591 		JBrowse link
G Tomm20 translocase of outer mitochondrial membrane 20 affects binding EXP tolcapone binds to TOMM20 protein CTD PMID:19783845 NCBI chr19:54,925,197...54,935,188
Ensembl chr19:54,923,402...54,935,198 		JBrowse link
G Tomm40 translocase of outer mitochondrial membrane 40 affects binding EXP tolcapone binds to TOMM40 protein CTD PMID:19783845 NCBI chr 1:79,358,781...79,370,882
Ensembl chr 1:79,358,786...79,370,915 		JBrowse link
G Tomm7 translocase of outer mitochondrial membrane 7 affects binding EXP tolcapone binds to TOMM7 protein CTD PMID:19783845 NCBI chr 4:11,305,122...11,311,963
Ensembl chr 4:11,305,110...11,311,962 		JBrowse link
G Tp53i3 tumor protein p53 inducible protein 3 decreases expression EXP Tolcapone results in decreased expression of TP53I3 mRNA CTD PMID:24136188 NCBI chr 6:27,818,327...27,825,753 JBrowse link
G Trappc2l trafficking protein particle complex subunit 2L decreases expression EXP tolcapone results in decreased expression of TRAPPC2L mRNA CTD PMID:24136188 NCBI chr19:50,662,507...50,666,193
Ensembl chr19:50,662,507...50,666,192 		JBrowse link
G Tspan6 tetraspanin 6 decreases expression EXP tolcapone results in decreased expression of TSPAN6 mRNA CTD PMID:24136188 NCBI chr  X:97,092,394...97,099,659
Ensembl chr  X:97,092,388...97,099,309 		JBrowse link
G Tubb6 tubulin, beta 6 class V affects binding EXP tolcapone binds to TUBB6 protein CTD PMID:19783845 NCBI chr18:60,943,394...60,953,031
Ensembl chr18:60,943,375...60,954,418 		JBrowse link
G Txndc17 thioredoxin domain containing 17 decreases expression EXP tolcapone results in decreased expression of TXNDC17 mRNA CTD PMID:24136188 NCBI chr10:56,832,749...56,835,721 JBrowse link
G Uchl3-ps1 ubiquitin C-terminal hydrolase L3, pseudogene 1 decreases expression EXP tolcapone results in decreased expression of UCHL3-PS1 mRNA CTD PMID:24136188 NCBI chr 3:161,856,954...161,857,835 JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 decreases glucuronidation
increases glucuronidation		 ISO UGT1A9 protein mutant form results in decreased glucuronidation of tolcapone
UGT1A9 protein results in increased glucuronidation of tolcapone		 CTD PMID:16344532 NCBI chr 9:88,696,981...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Uqcrc2 ubiquinol cytochrome c reductase core protein 2 affects binding EXP tolcapone binds to UQCRC2 protein CTD PMID:19783845 NCBI chr 1:175,167,933...175,198,499
Ensembl chr 1:175,167,894...175,199,453 		JBrowse link
G Uqcrfs1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 affects binding EXP tolcapone binds to UQCRFS1 protein CTD PMID:19783845 NCBI chr17:33,977,908...33,982,478
Ensembl chr17:33,977,921...33,982,479 		JBrowse link
G Uvrag UV radiation resistance associated increases expression EXP tolcapone results in increased expression of UVRAG mRNA CTD PMID:24136188 NCBI chr 1:153,185,356...153,442,200
Ensembl chr 1:153,185,395...153,442,136 		JBrowse link
G Vdac2 voltage-dependent anion channel 2 affects binding EXP tolcapone binds to VDAC2 protein CTD PMID:19783845 NCBI chr15:2,462,877...2,476,802
Ensembl chr15:2,463,056...2,476,553 		JBrowse link
G Vdac3 voltage-dependent anion channel 3 affects binding EXP tolcapone binds to VDAC3 protein CTD PMID:19783845 NCBI chr16:69,434,982...69,451,473
Ensembl chr16:69,435,005...69,451,471 		JBrowse link
G Vsnl1 visinin-like 1 affects binding EXP tolcapone binds to VSNL1 protein CTD PMID:19783845 NCBI chr 6:34,038,641...34,159,479
Ensembl chr 6:34,038,642...34,159,479 		JBrowse link
G Washc3 WASH complex subunit 3 decreases expression EXP tolcapone results in decreased expression of WASHC3 mRNA CTD PMID:24136188 NCBI chr 7:22,621,078...22,665,550
Ensembl chr 7:22,621,078...22,690,696 		JBrowse link
G Wfs1 wolframin ER transmembrane glycoprotein affects binding EXP tolcapone binds to WFS1 protein CTD PMID:19783845 NCBI chr14:73,810,478...73,834,993
Ensembl chr14:73,810,404...73,835,602 		JBrowse link
G Yars1 tyrosyl-tRNA synthetase 1 increases expression EXP Tolcapone results in increased expression of YARS1 mRNA CTD PMID:24136188 NCBI chr 5:141,535,815...141,564,029
Ensembl chr 5:141,535,759...141,563,833 		JBrowse link
G Yeats4 YEATS domain containing 4 decreases expression EXP tolcapone results in decreased expression of YEATS4 mRNA CTD PMID:24136188 NCBI chr 7:52,858,313...52,865,454
Ensembl chr 7:52,858,305...52,865,635 		JBrowse link
G Znrf1 zinc and ring finger 1 increases expression EXP tolcapone results in increased expression of ZNRF1 mRNA CTD PMID:24136188 NCBI chr19:39,496,414...39,581,600
Ensembl chr19:39,496,527...39,580,969 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19838
    role 19814
      application 19658
        pharmaceutical 19499
          drug 19499
            antidyskinesia agent 1552
              antiparkinson drug 1180
                tolcapone 346
Path 2
Term Annotations click to browse term
  CHEBI ontology 19838
    subatomic particle 19836
      composite particle 19836
        hadron 19836
          baryon 19836
            nucleon 19836
              atomic nucleus 19836
                atom 19836
                  main group element atom 19786
                    p-block element atom 19786
                      carbon group element atom 19734
                        carbon atom 19731
                          organic molecular entity 19731
                            heteroorganic entity 19488
                              organochalcogen compound 19251
                                organooxygen compound 19168
                                  carbonyl compound 18895
                                    ketone 17185
                                      aromatic ketone 12455
                                        benzophenones 1286
                                          tolcapone 346
paths to the root