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Gene: Rps27a (ribosomal protein S27a) Rattus norvegicus

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Symbol:

Rps27a

Name:

ribosomal protein S27a

RGD ID:

6489478

Description:

Predicted to enable protein tag activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in modification-dependent protein catabolic process; protein ubiquitination; and ribosomal small subunit biogenesis. Part of cytosolic small ribosomal subunit. Orthologous to human RPS27A (ribosomal protein S27a); PARTICIPATES IN ribosome biogenesis pathway; translation pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; aflatoxin B1.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC100912032; ubiquitin carboxyl extension protein 80; ubiquitin-40S ribosomal protein S27a; ubiquitin-40S ribosomal protein S27a-like

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	RPS27A (ribosomal protein S27a)	RGD	RGD
Mus musculus (house mouse):	Rps27a (ribosomal protein S27A)	RGD	RGD
Chinchilla lanigera (long-tailed chinchilla):	Rps27a (ribosomal protein S27a)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	RPS27A (ribosomal protein S27a)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	RPS27A (ribosomal protein S27a)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Rps27a (ribosomal protein S27a)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	RPS27A (ribosomal protein S27a)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	RPS27A (ribosomal protein S27a)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Rps27a (ribosomal protein S27a)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Rps27a (ribosomal protein S27a)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	UBC (ubiquitin C)	HGNC	Panther
Alliance orthologs ³
Homo sapiens (human):	RPS27A (ribosomal protein S27a)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Rps27a (ribosomal protein S27A)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	rps27a (ribosomal protein S27a)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	RpS27A	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	ubl-1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	RPS31	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	rps27a	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Related Pseudogenes:

Rps27a-ps1 Rps27a-ps10 Rps27a-ps11 Rps27a-ps12 Rps27a-ps13 Rps27a-ps14 Rps27a-ps15 Rps27a-ps16 Rps27a-ps18 Rps27a-ps19 Rps27a-ps2 Rps27a-ps20 Rps27a-ps21 Rps27a-ps23 Rps27a-ps24 Rps27a-ps25 Rps27a-ps26 Rps27a-ps28 Rps27a-ps29 Rps27a-ps3 Rps27a-ps30 Rps27a-ps31 Rps27a-ps4 Rps27a-ps5 Rps27a-ps6 Rps27a-ps7 Rps27a-ps8 Rps27a-ps9

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	14	107,486,664 - 107,488,941 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	14	107,486,664 - 107,488,941 (-)	Ensembl				GRCr8
mRatBN7.2	14	103,285,734 - 103,288,011 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	133,180,212 - 133,180,805 (-)	Ensembl				mRatBN7.2
mRatBN7.2 Ensembl	14	103,285,734 - 103,288,011 (-)	Ensembl				mRatBN7.2
mRatBN7.2 Ensembl	5	153,655,012 - 153,655,482 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	14	107,625,246 - 107,627,522 (-)	NCBI	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	14	108,858,738 - 108,861,015 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	14	105,331,167 - 105,333,444 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd	14	107,992,004 - 107,994,281 (-)	NCBI
Lyon_Normotensive	14	106,628,475 - 106,630,751 (-)	NCBI
Lyon_Hypertensive	14	108,174,580 - 108,176,856 (-)	NCBI
F344_StmMcwi	14	106,997,054 - 106,999,330 (-)	NCBI
Rnor_6.0	14	113,966,163 - 113,968,440 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	14	113,966,611 - 113,968,268 (-)	Ensembl		Rnor_6.0 Ensembl	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	138,628,482 - 138,629,026 (-)	Ensembl		Rnor_6.0 Ensembl	rn6	Rnor6.0
Rnor_5.0	14	113,632,952 - 113,634,814 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
Celera	14	102,162,278 - 102,164,555 (-)	NCBI		Celera
Cytogenetic Map	14	q22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Brain Injuries (IEP)

Breast Cancer, Familial (ISO)

Familial Prostate Cancer (ISO)

hepatocellular carcinoma (ISO)

stomach cancer (ISO)

urinary bladder cancer (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(1->4)-beta-D-glucan (ISO)

(S)-nicotine (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,6-dinitrotoluene (EXP)

2-hydroxypropanoic acid (ISO)

3,4-methylenedioxymethamphetamine (ISO)

4,4'-diaminodiphenylmethane (ISO)

4,4'-sulfonyldiphenol (ISO)

7,12-dimethyltetraphene (ISO)

acetylsalicylic acid (ISO)

aflatoxin B1 (EXP)

all-trans-retinoic acid (ISO)

ammonium chloride (EXP)

amosite asbestos (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenic trichloride (ISO)

arsenite(3-) (ISO)

arsenous acid (ISO)

atrazine (ISO)

Azaspiracid (ISO)

azoxystrobin (ISO)

benzatropine (ISO)

benzene (EXP)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bisphenol AF (ISO)

Butylbenzyl phthalate (ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

caffeine (ISO)

cannabidiol (ISO)

CGP 52608 (ISO)

chloropicrin (ISO)

cisplatin (ISO)

clofibric acid (EXP)

copper atom (ISO)

copper(0) (ISO)

crocidolite asbestos (ISO)

Cuprizon (ISO)

Cyclopamine (ISO)

cypermethrin (ISO)

DDT (EXP)

diarsenic trioxide (ISO)

dicrotophos (ISO)

dinophysistoxin 1 (ISO)

enzalutamide (ISO)

enzyme inhibitor (ISO)

epoxiconazole (ISO)

ethanol (EXP,ISO)

fenpyroximate (ISO)

fenthion (ISO)

fipronil (EXP)

folic acid (ISO)

FR900359 (ISO)

furan (EXP)

gentamycin (EXP)

glafenine (EXP)

haloperidol (ISO)

hydralazine (ISO)

indometacin (EXP)

isoprenaline (ISO)

ivermectin (ISO)

lipopolysaccharide (ISO)

manganese atom (ISO)

manganese(0) (ISO)

manganese(II) chloride (ISO)

methamphetamine (EXP)

methylparaben (ISO)

naphthalene (ISO)

nefazodone (EXP)

nicotine (ISO)

nimesulide (EXP)

paracetamol (ISO)

perfluorooctane-1-sulfonic acid (ISO)

picoxystrobin (ISO)

potassium dichromate (ISO)

pyrimidifen (ISO)

rac-lactic acid (ISO)

rotenone (ISO)

silicon dioxide (ISO)

sodium arsenite (ISO)

tetrachloromethane (EXP)

tolcapone (EXP)

triamcinolone acetonide (ISO)

tungsten (ISO)

valproic acid (ISO)

vinclozolin (EXP)

vorinostat (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

biological_process (ND)

modification-dependent protein catabolic process (IBA)

protein ubiquitination (IBA)

ribosomal small subunit biogenesis (ISO,ISS)

translation (IEA)

Cellular Component

cytoplasm (IEA,ISO)

cytosol (IEA,ISO)

cytosolic ribosome (IBA,ISO)

cytosolic small ribosomal subunit (IDA,ISO)

endoplasmic reticulum (ISO)

nucleolus (IEA,ISO)

nucleus (IBA,IEA)

ribosome (IEA)

small-subunit processome (ISO,ISS)

synapse (ISO)

Molecular Function

protein tag activity (IBA)

structural constituent of ribosome (IBA,IEA,ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

ribosome biogenesis pathway (ISO)

translation pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Structures of the human and Drosophila 80S ribosome.	Anger AM, etal., Nature. 2013 May 2;497(7447):80-5. doi: 10.1038/nature12104.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	Mass spectrometric analysis of 40 S ribosomal proteins from Rat-1 fibroblasts.	Louie DF, etal., J Biol Chem. 1996 Nov 8;271(45):28189-98.
4.	Functional dichotomy of ribosomal proteins during the synthesis of mammalian 40S ribosomal subunits.	O'Donohue MF, etal., J Cell Biol. 2010 Sep 6;190(5):853-66. doi: 10.1083/jcb.201005117.
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
6.	Comprehensive gene review and curation	RGD comprehensive gene curation
7.	Ubiquitin and ubiquitin-conjugated protein expression in the rat cerebral cortex and hippocampus following traumatic brain injury (TBI).	Yao X, etal., Brain Res. 2007 Nov 28;1182:116-22. Epub 2007 Sep 14.

Additional References at PubMed

PMID:925037	PMID:7488009	PMID:8031840	PMID:8706699	PMID:12477932	PMID:15057822	PMID:15632090	PMID:15883184	PMID:16502470	PMID:16791210	PMID:17634366	PMID:19190083
PMID:19199708	PMID:19946888	PMID:20458337	PMID:21630459	PMID:22658674	PMID:22681889	PMID:23376485	PMID:23533145	PMID:35352799

Genomics

Comparative Map Data

Rps27a
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	14	107,486,664 - 107,488,941 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	14	107,486,664 - 107,488,941 (-)	Ensembl				GRCr8
mRatBN7.2	14	103,285,734 - 103,288,011 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	133,180,212 - 133,180,805 (-)	Ensembl				mRatBN7.2
mRatBN7.2 Ensembl	14	103,285,734 - 103,288,011 (-)	Ensembl				mRatBN7.2
mRatBN7.2 Ensembl	5	153,655,012 - 153,655,482 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	14	107,625,246 - 107,627,522 (-)	NCBI	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	14	108,858,738 - 108,861,015 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	14	105,331,167 - 105,333,444 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd	14	107,992,004 - 107,994,281 (-)	NCBI
Lyon_Normotensive	14	106,628,475 - 106,630,751 (-)	NCBI
Lyon_Hypertensive	14	108,174,580 - 108,176,856 (-)	NCBI
F344_StmMcwi	14	106,997,054 - 106,999,330 (-)	NCBI
Rnor_6.0	14	113,966,163 - 113,968,440 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	14	113,966,611 - 113,968,268 (-)	Ensembl		Rnor_6.0 Ensembl	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	138,628,482 - 138,629,026 (-)	Ensembl		Rnor_6.0 Ensembl	rn6	Rnor6.0
Rnor_5.0	14	113,632,952 - 113,634,814 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
Celera	14	102,162,278 - 102,164,555 (-)	NCBI		Celera
Cytogenetic Map	14	q22	NCBI

RPS27A
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	55,231,903 - 55,235,853 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	55,229,447 - 55,236,649 (+)	Ensembl		GRCh38.p14 Ensembl	hg38	GRCh38
GRCh37	2	55,459,039 - 55,462,989 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	55,313,328 - 55,316,249 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	2	55,371,474 - 55,374,396	NCBI
Celera	2	55,299,565 - 55,303,515 (+)	NCBI		Celera
Cytogenetic Map	2	p16.1	NCBI
HuRef	2	55,193,794 - 55,197,744 (+)	NCBI		HuRef
CHM1_1	2	55,389,096 - 55,393,046 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	2	55,229,133 - 55,233,083 (+)	NCBI		T2T-CHM13v2.0

Rps27a
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	29,495,842 - 29,498,040 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	29,494,748 - 29,498,109 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	11	29,545,842 - 29,548,040 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	29,545,846 - 29,548,109 (-)	Ensembl		GRCm38.p6 Ensembl	mm10	GRCm38
MGSCv37	11	29,445,842 - 29,448,040 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	11	29,445,842 - 29,448,040 (-)	NCBI		MGSCv36	mm8
Celera	11	31,907,121 - 31,909,319 (-)	NCBI		Celera
Cytogenetic Map	11	A3.3	NCBI
cM Map	11	16.79	NCBI

Rps27a
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955424	27,823,575 - 27,825,489 (-)	Ensembl		ChiLan1.0 Ensembl
ChiLan1.0	NW_004955424	27,823,575 - 27,825,489 (-)	NCBI	ChiLan1.0	ChiLan1.0

RPS27A
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	12	71,090,568 - 71,094,414 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	2A	71,094,520 - 71,098,128 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2A	55,389,243 - 55,392,914 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2A	56,529,856 - 56,533,527 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2A	56,530,349 - 56,533,527 (+)	Ensembl		PanPan1.1 Ensembl	panPan2	panpan1.1

RPS27A
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	10	56,132,924 - 56,135,327 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	10	56,132,894 - 56,135,327 (+)	Ensembl		CanFam3.1 Ensembl	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	10	56,089,650 - 56,092,053 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	10	57,136,975 - 57,139,378 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	10	57,136,945 - 57,139,378 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	10	56,838,149 - 56,840,545 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	10	57,117,379 - 57,119,782 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	10	57,407,860 - 57,410,263 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Rps27a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mIctTri1.hap1	12	76,986,153 - 76,988,651 (-)	NCBI		mIctTri1.hap1
HiC_Itri_2	NW_024406292	26,938,453 - 26,940,987 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936491	1,630,128 - 1,635,952 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936491	1,630,172 - 1,632,839 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

RPS27A
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	85,986,501 - 85,992,503 (-)	Ensembl		Sscrofa11.1 Ensembl	susScr11	Sscrofa11.1
Sscrofa11.1	3	85,989,609 - 85,992,257 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	90,773,810 - 90,776,492 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

RPS27A
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mChlSab1.0.hap1	14	55,160,146 - 55,163,105 (+)	NCBI		mChlSab1.0.hap1
Vero_WHO_p1.0	NW_023666045	60,052,453 - 60,055,600 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0
ChlSab1.1	14	51,664,098 - 51,667,138 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	14	51,664,101 - 51,667,011 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM

Rps27a
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624833	6,309,342 - 6,311,762 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2
HetGla_female_1.0 Ensembl	NW_004624833	6,291,446 - 6,311,671 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
Naked mole-rat maternal Ensembl	4	85,774,474 - 85,777,866 (+)	Ensembl

Rps27a
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	11	97,165,178 - 97,167,236 (-)	NCBI	Rrattus_CSIRO_v1	Rrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	25
Count of miRNA genes:	23
Interacting mature miRNAs:	24
Transcripts:	ENSRNOT00000005872
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1641900	Alcrsp11	Alcohol response QTL 11			alcohol metabolism trait (VT:0015089)	blood ethanol level (CMO:0000535)	14	74255551	109089856	Rat
1582259	Gluco23	Glucose level QTL 23	3.1	0.0008	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	14	74255551	109089856	Rat

Markers in Region

RH128322

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Cytogenetic Map	18	p12	UniSTS
Cytogenetic Map	14	q22	UniSTS

PMC280674P2

Rat Assembly	Chr	Position (strand)	Source
Cytogenetic Map	14	q22	UniSTS
Cytogenetic Map	X	q21	UniSTS
Cytogenetic Map	19	q11	UniSTS

RH131424

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	14	107,486,721 - 107,486,938 (+)	Marker Load Pipeline
Rnor_5.0	14	113,632,011 - 113,632,228	NCBI	Rnor5.0
RGSC_v3.4	14	110,559,267 - 110,559,483	UniSTS	RGSC3.4
Celera	14	102,162,336 - 102,162,552	UniSTS
Cytogenetic Map	14	q22	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

adipose tissue	alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	entire extraembryonic component	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	pharyngeal arch	renal system	reproductive system	respiratory system	sensory system	visual system
283	165	740	1640	4180	1103	1819	133	934	521	916	162	5616	2694	448	4073	38	1438	801	940	160	158

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001305443	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_031113	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AABR07016777	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC058139	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473996	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FM074661	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ211529	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ213162	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ217581	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ217717	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ220688	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ221036	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ221107	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ221156	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ221208	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ221306	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ221767	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ222453	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ222481	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ222580	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ222775	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ222780	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ223105	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ223123	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ223173	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ223274	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ223327	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ223516	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ224268	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ226119	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ228579	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ228641	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ229678	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ230060	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000014	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	X81839	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000005872 ⟹ ENSRNOP00000005872

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	14	107,486,664 - 107,488,941 (-)	Ensembl
mRatBN7.2 Ensembl	14	103,285,734 - 103,288,011 (-)	Ensembl
Rnor_6.0 Ensembl	14	113,966,611 - 113,968,268 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000049535 ⟹ ENSRNOP00000048664

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	5	158,937,842 - 158,938,561 (+)	Ensembl

RefSeq Acc Id:

NM_001305443 ⟹ NP_001292372

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	107,486,664 - 107,488,885 (-)	NCBI
mRatBN7.2	14	103,285,734 - 103,287,955 (-)	NCBI
Dahl_SR_JrHsd	14	107,992,004 - 107,994,225 (-)	NCBI
Lyon_Normotensive	14	106,628,475 - 106,630,695 (-)	NCBI
Lyon_Hypertensive	14	108,174,580 - 108,176,800 (-)	NCBI
F344_StmMcwi	14	106,997,054 - 106,999,274 (-)	NCBI
Rnor_6.0	14	113,966,163 - 113,968,384 (-)	NCBI
Celera	14	102,162,278 - 102,164,499 (-)	NCBI

Sequence:

show sequence

GTTGGTGAGTGTGTGCTCTGTGGCCCGGCTCTGGCTAGTGGCTCTACCGGTCGCTCTCACTGGT
GTGGTCGGGTCTAATCCGTCTCTTTTCGAATGCAGGTGGAGCAGCCGCCACGATGCAGATTTTT
GTGAAGACCCTTACAGGGAAGACCATCACGCTCGAGGTTGAACCCTCGGACACTATAGAAAATG
TAAAGGCCAAGATCCAGGATAAGGAAGGAATTCCTCCTGATCAGCAGAGGTTGATCTTTGCTGG
TAAGCAGTTGGAAGATGGCCGTACTTTGTCTGACTACAACATTCAAAAGGAGTCCACTCTCCAT
CTCGTGCTGAGACTTCGTGGTGGCGCTAAGAAAAGGAAGAAGAAGTCTTACACCACCCCAAAGA
AGAACAAGCATAAGAGAAAGAAGGTCAAGTTGGCTGTGCTGAAATACTATAAGGTGGATGAAAA
TGGCAAAATCAGCCGACTTCGTCGGGAATGTCCTTCTGATGAATGTGGTGCTGGAGTTTTCATG
GGTAGCCACTTTGACAGGCATTACTGTGGCAAGTGTTGTCTGACTTACTGCTTCAACAAACCAG
AAGACAAGTAGTTGTGTATGAGTTAATAAAGAGAAGGAACTGATGTTTAGTATTGTGTTTTATT
ATTGTTTAAGCAATGTTTCTTCAGCTGTGTAACAGTCCTTGGTCAGGAGAGTTTGATCGTAATG
GTAAGCCATCTTGGCTTTGGCTTTCCTGGCAGGCACAAAGGTCAGAATTCTTTAAGGGGTTGTG
GGATATCCTGTAGACTTGGAAGTAGTGTGATCTTGTCTTACGAGACATGAGAGTAGTCTCACAG
TACATTCAAGATGCTTCCTGAGGTTGGCTATGTGTGTGAGCTGTTAAATATTTTCAGTGTTGAT
GGTGATTTTTCCTCTATAAGAGGTAAGCTAGGCATGTGGTGCATAGTTAAGGTTTCAGCACTTG
GGAGACTTCAGCAGGAGATTTGCTGCCAGCTTGTGCCAGCAAGACACTGTATTTAAATAAAGAA
ACGAAAACAAA

hide sequence

RefSeq Acc Id:

NM_031113 ⟹ NP_112375

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	107,486,664 - 107,488,941 (-)	NCBI
mRatBN7.2	14	103,285,734 - 103,288,011 (-)	NCBI
Dahl_SR_JrHsd	14	107,992,004 - 107,994,281 (-)	NCBI
Lyon_Normotensive	14	106,628,475 - 106,630,751 (-)	NCBI
Lyon_Hypertensive	14	108,174,580 - 108,176,856 (-)	NCBI
F344_StmMcwi	14	106,997,054 - 106,999,330 (-)	NCBI
Rnor_6.0	14	113,966,163 - 113,968,440 (-)	NCBI
Celera	14	102,162,278 - 102,164,555 (-)	NCBI

Sequence:

show sequence

CTTCGACCCGGAGACTCGGTCAGCCACGCTTGGCTCTTCCTTTCCGATCCGCCATCGTTGGTGG
AGCAGCCGCCACGATGCAGATTTTTGTGAAGACCCTTACAGGGAAGACCATCACGCTCGAGGTT
GAACCCTCGGACACTATAGAAAATGTAAAGGCCAAGATCCAGGATAAGGAAGGAATTCCTCCTG
ATCAGCAGAGGTTGATCTTTGCTGGTAAGCAGTTGGAAGATGGCCGTACTTTGTCTGACTACAA
CATTCAAAAGGAGTCCACTCTCCATCTCGTGCTGAGACTTCGTGGTGGCGCTAAGAAAAGGAAG
AAGAAGTCTTACACCACCCCAAAGAAGAACAAGCATAAGAGAAAGAAGGTCAAGTTGGCTGTGC
TGAAATACTATAAGGTGGATGAAAATGGCAAAATCAGCCGACTTCGTCGGGAATGTCCTTCTGA
TGAATGTGGTGCTGGAGTTTTCATGGGTAGCCACTTTGACAGGCATTACTGTGGCAAGTGTTGT
CTGACTTACTGCTTCAACAAACCAGAAGACAAGTAGTTGTGTATGAGTTAATAAAGAGAAGGAA
CTGATGTTTAGTATTGTGTTTTATTATTGTTTAAGCAATGTTTCTTCAGCTGTGTAACAGTCCT
TGGTCAGGAGAGTTTGATCGTAATGGTAAGCCATCTTGGCTTTGGCTTTCCTGGCAGGCACAAA
GGTCAGAATTCTTTAAGGGGTTGTGGGATATCCTGTAGACTTGGAAGTAGTGTGATCTTGTCTT
ACGAGACATGAGAGTAGTCTCACAGTACATTCAAGATGCTTCCTGAGGTTGGCTATGTGTGTGA
GCTGTTAAATATTTTCAGTGTTGATGGTGATTTTTCCTCTATAAGAGGTAAGCTAGGCATGTGG
TGCATAGTTAAGGTTTCAGCACTTGGGAGACTTCAGCAGGAGATTTGCTGCCAGCTTGTGCCAG
CAAGACACTGTATTTAAATAAAGAAACGAAAACAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001292372	(Get FASTA)	NCBI Sequence Viewer
	NP_112375	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH58139	(Get FASTA)	NCBI Sequence Viewer
	CAA57432	(Get FASTA)	NCBI Sequence Viewer
	EDL98032	(Get FASTA)	NCBI Sequence Viewer
	EDL98033	(Get FASTA)	NCBI Sequence Viewer
	EDL98034	(Get FASTA)	NCBI Sequence Viewer
	EDL98035	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000005872
	ENSRNOP00000005872.1
	ENSRNOP00055004260
	ENSRNOP00055020526
	ENSRNOP00060009368
	ENSRNOP00060029590
	ENSRNOP00065001313
	ENSRNOP00065023884
GenBank Protein	P62982	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_112375 ⟸ NM_031113
- UniProtKB:	Q9D2W3 (UniProtKB/Swiss-Prot), P49664 (UniProtKB/Swiss-Prot), P62982 (UniProtKB/Swiss-Prot), Q6PED0 (UniProtKB/TrEMBL), A0A8I6G8I7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKE STLHLVLRLRGGAKKRKKKSYTTPKKNKHKRKKVKLAVLKYYKVDENGKISRLRRECPSDECGA GVFMGSHFDRHYCGKCCLTYCFNKPEDK hide sequence

RefSeq Acc Id:	NP_001292372 ⟸ NM_001305443
- UniProtKB:	Q9D2W3 (UniProtKB/Swiss-Prot), P49664 (UniProtKB/Swiss-Prot), P62982 (UniProtKB/Swiss-Prot), Q6PED0 (UniProtKB/TrEMBL), A0A8I6G8I7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKE STLHLVLRLRGGAKKRKKKSYTTPKKNKHKRKKVKLAVLKYYKVDENGKISRLRRECPSDECGA GVFMGSHFDRHYCGKCCLTYCFNKPEDK hide sequence

Ensembl Acc Id:

ENSRNOP00000005872 ⟸ ENSRNOT00000005872

Ensembl Acc Id:

ENSRNOP00000048664 ⟸ ENSRNOT00000049535

Protein Domains

Ubiquitin-like

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P62982-F1-model_v2	AlphaFold	P62982	1-156	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:6489478	AgrOrtholog
BioCyc Gene	G2FUF-14649	BioCyc
Ensembl Genes	ENSRNOG00000004426	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
	ENSRNOG00000034246	Ensembl
	ENSRNOG00000051047	Ensembl
	ENSRNOG00055003627	UniProtKB/Swiss-Prot
	ENSRNOG00055014645	UniProtKB/Swiss-Prot
	ENSRNOG00060007519	UniProtKB/Swiss-Prot
	ENSRNOG00060020782	UniProtKB/Swiss-Prot
	ENSRNOG00065001421	UniProtKB/Swiss-Prot
	ENSRNOG00065017945	UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000005872	ENTREZGENE
	ENSRNOT00000005872.5	UniProtKB/Swiss-Prot
	ENSRNOT00055005682	UniProtKB/Swiss-Prot
	ENSRNOT00055025102	UniProtKB/Swiss-Prot
	ENSRNOT00060012391	UniProtKB/Swiss-Prot
	ENSRNOT00060035959	UniProtKB/Swiss-Prot
	ENSRNOT00065001879	UniProtKB/Swiss-Prot
	ENSRNOT00065030041	UniProtKB/Swiss-Prot
Gene3D-CATH	6.20.50.150	UniProtKB/Swiss-Prot
	Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1	UniProtKB/Swiss-Prot
InterPro	Ribosomal_S27a	UniProtKB/Swiss-Prot
	Ribosomal_zn-bd	UniProtKB/Swiss-Prot
	S27a-like_sf	UniProtKB/Swiss-Prot
	Ubiquitin	UniProtKB/Swiss-Prot
	Ubiquitin-like_domsf	UniProtKB/Swiss-Prot
	Ubiquitin_CS	UniProtKB/Swiss-Prot
	Ubiquitin_dom	UniProtKB/Swiss-Prot
	Ubiquitin_ubiquitin-like	UniProtKB/Swiss-Prot
KEGG Report	rno:100912032	UniProtKB/Swiss-Prot
NCBI Gene	LOC100912032	ENTREZGENE
PANTHER	UBIQUITIN	UniProtKB/Swiss-Prot
Pfam	Ribosomal_S27	UniProtKB/Swiss-Prot
	ubiquitin	UniProtKB/Swiss-Prot
PhenoGen	Rps27a	PhenoGen
PRINTS	UBIQUITIN	UniProtKB/Swiss-Prot
PROSITE	UBIQUITIN_1	UniProtKB/Swiss-Prot
	UBIQUITIN_2	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000004426	RatGTEx
	ENSRNOG00000034246	RatGTEx
	ENSRNOG00000051047	RatGTEx
	ENSRNOG00055003627	RatGTEx
	ENSRNOG00055014645	RatGTEx
	ENSRNOG00060007519	RatGTEx
	ENSRNOG00060020782	RatGTEx
	ENSRNOG00065001421	RatGTEx
	ENSRNOG00065017945	RatGTEx
SMART	Ribosomal_S27	UniProtKB/Swiss-Prot
	UBQ	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF54236	UniProtKB/Swiss-Prot
	SSF57829	UniProtKB/Swiss-Prot
UniProt	A0A8I6G8I7	ENTREZGENE, UniProtKB/TrEMBL
	P49664	ENTREZGENE
	P62982	ENTREZGENE
	Q6PED0	ENTREZGENE, UniProtKB/TrEMBL
	Q9D2W3	ENTREZGENE
	RS27A_RAT	UniProtKB/Swiss-Prot
UniProt Secondary	P02248	UniProtKB/Swiss-Prot
	P02249	UniProtKB/Swiss-Prot
	P02250	UniProtKB/Swiss-Prot
	P49664	UniProtKB/Swiss-Prot
	P62989	UniProtKB/Swiss-Prot
	Q29120	UniProtKB/Swiss-Prot
	Q63446	UniProtKB/Swiss-Prot
	Q91887	UniProtKB/Swiss-Prot
	Q91888	UniProtKB/Swiss-Prot
	Q9D2W3	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-03-16	Rps27a	ribosomal protein S27a	LOC100912032	ubiquitin-40S ribosomal protein S27a-like	Name and Symbol changed	629549	APPROVED
2012-07-05	LOC100912032	ubiquitin-40S ribosomal protein S27a-like			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

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Imported Disease Annotations - ClinVar

RGD Manual Annotations