RPS27A (ribosomal protein S27a) - Rat Genome Database

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Keyword

Gene: RPS27A (ribosomal protein S27a) Homo sapiens

Symbol:

RPS27A

Name:

ribosomal protein S27a

Description:

Ubiquitin, a highly conserved protein that has a major role in targeting cellular proteins for degradation by the 26S proteosome, is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin fused to an unrelated protein. This gene encodes a fusion protein consisting of ubiquitin at the N terminus and ribosomal protein S27a at the C terminus. When expressed in yeast, the protein is post-translationally processed, generating free ubiquitin monomer and ribosomal protein S27a. Ribosomal protein S27a is a component of the 40S subunit of the ribosome and belongs to the S27AE family of ribosomal proteins. It contains C4-type zinc finger domains and is located in the cytoplasm. Pseudogenes derived from this gene are present in the genome. As with ribosomal protein S27a, ribosomal protein L40 is also synthesized as a fusion protein with ubiquitin; similarly, ribosomal protein S30 is synthesized as a fusion protein with the ubiquitin-like protein fubi. Multiple alternatively spliced transcript variants that encode the same proteins have been identified.[provided by RefSeq, Sep 2008]

Type:

protein-coding

RefSeq Status:

REVIEWED

Also known as:

40S ribosomal protein S27a; CEP80; HUBCEP80; OTTHUMP00000200786; OTTHUMP00000200788; OTTHUMP00000200789; OTTHUMP00000201692; S27A; UBA80; UBC; UBCEP1; UBCEP80; ubiquitin and ribosomal protein S27a; ubiquitin C; ubiquitin carboxyl extension protein 80; ubiquitin-40S ribosomal protein S27a; ubiquitin-CEP80

Orthologs:

Mus musculus : Rps27a (ribosomal protein S27A) MGI
Rattus norvegicus : Rps27a (ribosomal protein S27a)

Related Pseudogenes:

RPS27AP1 RPS27AP10 RPS27AP11 RPS27AP12 RPS27AP13 RPS27AP14 RPS27AP15 RPS27AP16 RPS27AP17 RPS27AP2 RPS27AP3 RPS27AP4 RPS27AP5 RPS27AP6 RPS27AP7 RPS27AP8 RPS27AP9

Latest Assembly:

Human Genome Assembly GRCh37

Position:

Map	Chr	Position	Strand	Source
Human Alternate Assembly CHM1_1	2	55,325,318 - 55,329,268	+	NCBI
Human Genome Assembly HuRef	2	55,193,794 - 55,197,744	+	NCBI
Human Genome Assembly GRCh37	2	55,459,039 - 55,462,989	+	NCBI
Human Genome Assembly Build 36	2	55,313,328 - 55,316,249	+	NCBI
Human Cytogenetic Map	2	p16		NCBI
Human Genome Assembly	2	55,371,474 - 55,374,396		NCBI