Gene: Akr1d1 (aldo-keto reductase family 1, member D1) Rattus norvegicus
Symbol: Akr1d1
Name: aldo-keto reductase family 1, member D1
Description: ENCODES a protein that exhibits 3-oxo-5-beta-steroid 4-dehydrogenase activity; INVOLVED IN androgen metabolic process (ortholog); bile acid biosynthetic process (ortholog); C21-steroid hormone metabolic process (ortholog); PARTICIPATES IN 11-beta-hydroxylase deficiency pathway; 17-alpha-hydroxylase deficiency pathway; 21-alpha-hydroxylase deficiency pathway; ASSOCIATED WITH Bile Acid Synthesis Defect, Congenital, 2 (ortholog); congenital bile acid synthesis defect (ortholog); Hemochromatosis (ortholog); FOUND IN cytosol (ortholog); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl
Type: protein-coding
Also known as: 3-oxo-5-beta-steroid 4-dehydrogenase; aldo-keto reductase family 1 member D1; aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase); delta(4)-3-ketosteroid 5-beta-reductase; delta(4)-3-oxosteroid 5-beta-reductase
Homo sapiens (human) : AKR1D1 (aldo-keto reductase family 1 member D1)  HGNC  AGR
Mus musculus (house mouse) : Akr1d1 (aldo-keto reductase family 1, member D1)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Akr1d1 (aldo-keto reductase family 1 member D1)
Pan paniscus (bonobo/pygmy chimpanzee) : AKR1D1 (aldo-keto reductase family 1 member D1)
Canis lupus familiaris (dog) : LOC491379 (3-oxo-5-beta-steroid 4-dehydrogenase-like)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Akr1d1 (aldo-keto reductase family 1 member D1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0465,110,706 - 65,143,930 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0464,933,143 - 64,965,930 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4464,972,908 - 65,005,896 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1465,249,037 - 65,282,026 (+)NCBI
Celera461,186,796 - 61,219,854 (+)NCBICelera
Cytogenetic Map4q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Akr1d1
AGR Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620752
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2017-10-03
Status: ACTIVE