Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-schisandrin B | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of DDX18 mRNA] | CTD | PMID:31150632 | 1,2-dimethylhydrazine | multiple interactions | ISO | Ddx18 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DDX18 mRNA | CTD | PMID:22206623 | 1-chloro-2,4-dinitrobenzene | affects binding | ISO | DDX18 (Homo sapiens) | 6480464 | Dinitrochlorobenzene binds to DDX18 protein | CTD | PMID:32991956 | 17beta-estradiol | increases expression | ISO | DDX18 (Homo sapiens) | 6480464 | Estradiol results in increased expression of DDX18 mRNA | CTD | PMID:31614463 | 2,2',4,4'-Tetrabromodiphenyl ether | affects expression | ISO | Ddx18 (Mus musculus) | 6480464 | 2 more ... | CTD | PMID:30294300 | 2,2',4,4'-Tetrabromodiphenyl ether | decreases expression | ISO | DDX18 (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:31675489 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of DDX18 mRNA | CTD | PMID:33387578 | 2,4,6-tribromophenol | decreases expression | ISO | DDX18 (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:31675489 | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 4-dinitrotoluene affects the expression of DDX18 mRNA | CTD | PMID:21346803 | 2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 6-dinitrotoluene affects the expression of DDX18 mRNA | CTD | PMID:21346803 | 2-hydroxypropanoic acid | decreases expression | ISO | DDX18 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of DDX18 mRNA | CTD | PMID:30851411 | 2-methylcholine | affects expression | ISO | DDX18 (Homo sapiens) | 6480464 | beta-methylcholine affects the expression of DDX18 mRNA | CTD | PMID:21179406 | 3,3',5,5'-tetrabromobisphenol A | increases expression | ISO | DDX18 (Homo sapiens) | 6480464 | tetrabromobisphenol A results in increased expression of DDX18 protein | CTD | PMID:31675489 | 3-chloropropane-1,2-diol | increases expression | EXP | | 6480464 | alpha-Chlorohydrin results in increased expression of DDX18 protein | CTD | PMID:34915118 | 4,4'-sulfonyldiphenol | increases expression | ISO | DDX18 (Homo sapiens) | 6480464 | bisphenol S results in increased expression of DDX18 protein | CTD | PMID:34186270 | 4-amino-2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 4-amino-2 and 6-dinitrotoluene affects the expression of DDX18 mRNA | CTD | PMID:21346803 | acetylsalicylic acid | decreases expression | ISO | DDX18 (Homo sapiens) | 6480464 | Aspirin results in decreased expression of DDX18 mRNA | CTD | PMID:11906190 | all-trans-retinoic acid | multiple interactions | ISO | DDX18 (Homo sapiens) | 6480464 | Thiophenes analog promotes the reaction [Tretinoin results in decreased expression of DDX18 mRNA] | CTD | PMID:16140955 | all-trans-retinoic acid | decreases expression | ISO | DDX18 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of DDX18 mRNA | CTD | PMID:15498508 more ... | aristolochic acid A | decreases expression | ISO | DDX18 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of DDX18 mRNA | CTD | PMID:33212167 | Aroclor 1254 | decreases expression | ISO | Ddx18 (Mus musculus) | 6480464 | Chlorodiphenyl (54% Chlorine) results in decreased expression of DDX18 mRNA | CTD | PMID:23650126 | atrazine | decreases expression | ISO | DDX18 (Homo sapiens) | 6480464 | Atrazine results in decreased expression of DDX18 mRNA | CTD | PMID:22378314 | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of DDX18 mRNA | CTD | PMID:25181051 | bisphenol A | decreases expression | ISO | DDX18 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of DDX18 protein | CTD | PMID:37567409 | caffeine | decreases phosphorylation | ISO | DDX18 (Homo sapiens) | 6480464 | Caffeine results in decreased phosphorylation of DDX18 protein | CTD | PMID:35688186 | cannabidiol | increases expression | ISO | DDX18 (Homo sapiens) | 6480464 | Cannabidiol results in increased expression of DDX18 mRNA | CTD | PMID:27918106 | CGP 52608 | multiple interactions | ISO | DDX18 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to DDX18 gene] | CTD | PMID:28238834 | chloroprene | increases expression | EXP | | 6480464 | Chloroprene results in increased expression of DDX18 mRNA | CTD | PMID:23125180 | cisplatin | multiple interactions | ISO | DDX18 (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in decreased expression of DDX18 mRNA | CTD | PMID:27392435 | cyclosporin A | increases expression | ISO | DDX18 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of DDX18 mRNA | CTD | PMID:20106945 | decabromodiphenyl ether | increases expression | ISO | DDX18 (Homo sapiens) | 6480464 | decabromobiphenyl ether results in increased expression of DDX18 protein | CTD | PMID:31675489 | dibutyl phthalate | decreases expression | ISO | Ddx18 (Mus musculus) | 6480464 | Dibutyl Phthalate results in decreased expression of DDX18 mRNA | CTD | PMID:17361019 and PMID:21266533 | dicrotophos | decreases expression | ISO | DDX18 (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of DDX18 mRNA | CTD | PMID:28302478 | disodium selenite | increases expression | ISO | DDX18 (Homo sapiens) | 6480464 | Sodium Selenite results in increased expression of DDX18 mRNA | CTD | PMID:18175754 | elemental selenium | decreases expression | ISO | DDX18 (Homo sapiens) | 6480464 | Selenium results in decreased expression of DDX18 mRNA | CTD | PMID:19244175 | elemental selenium | multiple interactions | ISO | DDX18 (Homo sapiens) | 6480464 | [Selenium co-treated with Vitamin E] results in decreased expression of DDX18 mRNA | CTD | PMID:19244175 | enzyme inhibitor | multiple interactions | ISO | DDX18 (Homo sapiens) | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of DDX18 protein | CTD | PMID:23301498 | ethyl methanesulfonate | decreases expression | ISO | DDX18 (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in decreased expression of DDX18 mRNA | CTD | PMID:23649840 | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of DDX18 mRNA | CTD | PMID:24136188 | folic acid | multiple interactions | ISO | Ddx18 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DDX18 mRNA | CTD | PMID:22206623 | formaldehyde | decreases expression | ISO | DDX18 (Homo sapiens) | 6480464 | Formaldehyde results in decreased expression of DDX18 mRNA | CTD | PMID:23649840 | FR900359 | decreases phosphorylation | ISO | DDX18 (Homo sapiens) | 6480464 | FR900359 results in decreased phosphorylation of DDX18 protein | CTD | PMID:37730182 | ivermectin | decreases expression | ISO | DDX18 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of DDX18 protein | CTD | PMID:32959892 | methyl methanesulfonate | decreases expression | ISO | DDX18 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in decreased expression of DDX18 mRNA | CTD | PMID:23649840 | paracetamol | affects expression | ISO | Ddx18 (Mus musculus) | 6480464 | Acetaminophen affects the expression of DDX18 mRNA | CTD | PMID:17562736 | paracetamol | decreases expression | ISO | DDX18 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of DDX18 mRNA | CTD | PMID:21420995 | rac-lactic acid | decreases expression | ISO | DDX18 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of DDX18 mRNA | CTD | PMID:30851411 | resveratrol | decreases expression | ISO | Ddx18 (Mus musculus) | 6480464 | resveratrol results in decreased expression of DDX18 protein | CTD | PMID:25505154 | SB 431542 | multiple interactions | ISO | DDX18 (Homo sapiens) | 6480464 | [LDN 193189 co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with FGF2 protein] results in decreased expression of DDX18 protein | CTD | PMID:37664457 | selenium atom | decreases expression | ISO | DDX18 (Homo sapiens) | 6480464 | Selenium results in decreased expression of DDX18 mRNA | CTD | PMID:19244175 | selenium atom | multiple interactions | ISO | DDX18 (Homo sapiens) | 6480464 | [Selenium co-treated with Vitamin E] results in decreased expression of DDX18 mRNA | CTD | PMID:19244175 | sodium dichromate | increases expression | EXP | | 6480464 | sodium bichromate results in increased expression of DDX18 mRNA | CTD | PMID:25993096 | sunitinib | increases expression | ISO | DDX18 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of DDX18 mRNA | CTD | PMID:31533062 | tamibarotene | affects expression | ISO | DDX18 (Homo sapiens) | 6480464 | tamibarotene affects the expression of DDX18 mRNA | CTD | PMID:15498508 | temozolomide | increases expression | ISO | DDX18 (Homo sapiens) | 6480464 | Temozolomide results in increased expression of DDX18 mRNA | CTD | PMID:31758290 | tetrachloromethane | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of DDX18 mRNA] | CTD | PMID:31150632 | tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of DDX18 mRNA | CTD | PMID:31150632 | tetrachloromethane | increases expression | ISO | Ddx18 (Mus musculus) | 6480464 | Carbon Tetrachloride results in increased expression of DDX18 mRNA | CTD | PMID:27339419 | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of DDX18 mRNA | CTD | PMID:23411599 and PMID:34492290 | thiophenes | multiple interactions | ISO | DDX18 (Homo sapiens) | 6480464 | Thiophenes analog promotes the reaction [Tretinoin results in decreased expression of DDX18 mRNA] | CTD | PMID:16140955 | tolcapone | affects binding | EXP | | 6480464 | tolcapone binds to DDX18 protein | CTD | PMID:19783845 | tungsten | decreases expression | ISO | Ddx18 (Mus musculus) | 6480464 | Tungsten results in decreased expression of DDX18 mRNA | CTD | PMID:30912803 | vinclozolin | increases expression | EXP | | 6480464 | vinclozolin results in increased expression of DDX18 mRNA | CTD | PMID:23034163 | vitamin E | multiple interactions | ISO | DDX18 (Homo sapiens) | 6480464 | [Selenium co-treated with Vitamin E] results in decreased expression of DDX18 mRNA | CTD | PMID:19244175 | vitamin E | decreases expression | ISO | DDX18 (Homo sapiens) | 6480464 | Vitamin E results in decreased expression of DDX18 mRNA | CTD | PMID:19244175 | |