Ddx18 (DEAD-box helicase 18) - Rat Genome Database

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Gene: Ddx18 (DEAD-box helicase 18) Rattus norvegicus
Analyze
Symbol: Ddx18
Name: DEAD-box helicase 18
RGD ID: 1549712
Description: Involved in cellular response to estradiol stimulus. Predicted to be located in chromosome. Predicted to be active in nucleolus. Orthologous to human DDX18 (DEAD-box helicase 18); PARTICIPATES IN ribosome biogenesis pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding (Ensembl: pseudogene)
RefSeq Status: PROVISIONAL
Previously known as: ATP-dependent RNA helicase DDX18; DEAD (Asp-Glu-Ala-Asp) box polypeptide 18; MGC95311; MrDb; Myc-regulated DEAD box protein; similar to RIKEN cDNA 2310005B10
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
NCBI Annotation Information: Annotation category: suggests misassembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81335,282,391 - 35,296,038 (-)NCBIGRCr8
mRatBN7.21332,729,697 - 32,743,161 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1332,729,700 - 32,743,161 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1335,292,118 - 35,305,666 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01336,580,015 - 36,593,563 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01333,854,534 - 33,868,075 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01337,522,558 - 37,536,066 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1337,522,561 - 37,536,066 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01342,680,394 - 42,693,902 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41333,587,928 - 33,601,436 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1332,594,103 - 32,607,613 (-)NCBICelera
Cytogenetic Map13q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
chromosome  (ISO)
nucleolus  (ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Myc-Max heterodimers activate a DEAD box gene and interact with multiple E box-related sites in vivo. Grandori C, etal., EMBO J. 1996 Aug 15;15(16):4344-57.
3. DExD/H-box RNA helicases in ribosome biogenesis. Martin R, etal., RNA Biol. 2013 Jan;10(1):4-18. doi: 10.4161/rna.21879. Epub 2012 Aug 24.
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Comprehensive gene review and curation RGD comprehensive gene curation
8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:16963496   PMID:19946888   PMID:20813266   PMID:22658674   PMID:22681889  


Genomics

Comparative Map Data
Ddx18
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81335,282,391 - 35,296,038 (-)NCBIGRCr8
mRatBN7.21332,729,697 - 32,743,161 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1332,729,700 - 32,743,161 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1335,292,118 - 35,305,666 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01336,580,015 - 36,593,563 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01333,854,534 - 33,868,075 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01337,522,558 - 37,536,066 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1337,522,561 - 37,536,066 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01342,680,394 - 42,693,902 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41333,587,928 - 33,601,436 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1332,594,103 - 32,607,613 (-)NCBICelera
Cytogenetic Map13q11NCBI
DDX18
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382117,814,691 - 117,832,377 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2117,814,691 - 117,832,377 (+)EnsemblGRCh38hg38GRCh38
GRCh372118,572,267 - 118,589,953 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362118,288,725 - 118,306,423 (+)NCBINCBI36Build 36hg18NCBI36
Build 342118,288,484 - 118,306,183NCBI
Celera2111,899,413 - 111,917,115 (+)NCBICelera
Cytogenetic Map2q14.1NCBI
HuRef2110,899,351 - 110,917,048 (+)NCBIHuRef
CHM1_12118,576,084 - 118,593,783 (+)NCBICHM1_1
T2T-CHM13v2.02118,247,963 - 118,265,651 (+)NCBIT2T-CHM13v2.0
Ddx18
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391121,481,564 - 121,495,709 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1121,481,564 - 121,495,718 (-)EnsemblGRCm39 Ensembl
GRCm381121,553,835 - 121,567,980 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1121,553,835 - 121,567,989 (-)EnsemblGRCm38mm10GRCm38
MGSCv371123,450,412 - 123,464,557 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361123,381,385 - 123,395,474 (-)NCBIMGSCv36mm8
Celera1124,194,901 - 124,209,051 (-)NCBICelera
Cytogenetic Map1E2.3NCBI
cM Map152.98NCBI
Ddx18
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545911,800,684 - 11,810,876 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545911,799,435 - 11,810,973 (-)NCBIChiLan1.0ChiLan1.0
DDX18
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21319,840,884 - 19,858,690 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B19,855,856 - 19,873,662 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B4,772,668 - 4,790,366 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B118,358,168 - 118,375,908 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B118,358,168 - 118,375,910 (+)Ensemblpanpan1.1panPan2
DDX18
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11932,014,586 - 32,030,634 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1932,015,512 - 32,030,602 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1932,282,705 - 32,298,733 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01933,407,420 - 33,423,471 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1933,407,427 - 33,423,422 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11932,083,578 - 32,099,618 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01932,253,818 - 32,270,107 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01933,443,099 - 33,459,140 (-)NCBIUU_Cfam_GSD_1.0
Ddx18
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530389,243,288 - 89,258,094 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493646952,361,081 - 52,374,358 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493646952,359,653 - 52,374,471 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DDX18
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1523,425,669 - 23,442,980 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11523,425,674 - 23,442,985 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21526,805,698 - 26,823,004 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DDX18
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11012,455,877 - 12,473,670 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1012,457,543 - 12,473,655 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606110,151,103 - 10,168,776 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ddx18
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473227,416,851 - 27,432,397 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ddx18
199 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:30
Count of miRNA genes:30
Interacting mature miRNAs:30
Transcripts:ENSRNOT00000037203
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2317027Aia22Adjuvant induced arthritis QTL 222.29joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)13134266636Rat
738036Lnnr4Liver neoplastic nodule remodeling QTL 43.64liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)13142356786Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131101056920Rat
631672Iddm12Insulin dependent diabetes mellitus QTL 122.20.0032blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)13599466834535351Rat
61339Bp24Blood pressure QTL 240.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)13599466844807491Rat
1581554Pur11Proteinuria QTL 11urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13599483377046787Rat
1581573Uae36Urinary albumin excretion QTL 36urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13599483377046787Rat
1581570Eae17Experimental allergic encephalomyelitis QTL 174.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)138897350101631289Rat
7411662Foco29Food consumption QTL 2920.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)13931346554313465Rat
9589141Insul28Insulin level QTL 2810.820.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)13931346554313465Rat
2317040Aia21Adjuvant induced arthritis QTL 212.75joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)13983154154831541Rat
2317046Aia8Adjuvant induced arthritis QTL 83.9700000286102295joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)13983154154831541Rat
1300163Cardf1Cardiac cell morphology QTL 14.18aorta morphology trait (VT:0000272)artery lesion measurement (CMO:0000975)131192944945417941Rat
2302275Gluco37Glucose level QTL 373.8blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)131192944946193066Rat
631645Bp121Blood pressure QTL 1213.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131491565559915655Rat
9589164Gluco66Glucose level QTL 666.670.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)131515872260158722Rat
1331784Bp222Blood pressure QTL 2222.944arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)131769443653050594Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1320605871101339738Rat
61391Bp5Blood pressure QTL 55.6arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)132230187567301875Rat
70170Eae14Experimental allergic encephalomyelitis QTL 140.0024nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)132320344868203448Rat
6893338Cm76Cardiac mass QTL 7600.99heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)132369296968692969Rat
1558644Cm45Cardiac mass QTL 453.60.002heart mass (VT:0007028)heart wet weight (CMO:0000069)132369296968692969Rat
2303030Bp327Blood pressure QTL 327arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133039535141184251Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1330395351101056920Rat
2301962Cm72Cardiac mass QTL 724.12heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)133124133158363171Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)133124133193395974Rat
2303563Bw89Body weight QTL 896body mass (VT:0001259)body weight (CMO:0000012)133228447177284471Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 31 57 41 19 41 3 5 73 35 41 11 3
Low 12 5 6 1 5
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000037203   ⟹   ENSRNOP00000038728
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1332,729,700 - 32,743,161 (-)Ensembl
Rnor_6.0 Ensembl1337,522,561 - 37,536,066 (-)Ensembl
RefSeq Acc Id: NM_001006996   ⟹   NP_001006997
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81335,282,464 - 35,295,972 (-)NCBI
mRatBN7.21332,729,697 - 32,743,161 (-)NCBI
Rnor_6.01337,522,558 - 37,536,066 (-)NCBI
Rnor_5.01342,680,394 - 42,693,902 (-)NCBI
RGSC_v3.41333,587,928 - 33,601,436 (-)RGD
Celera1332,594,103 - 32,607,613 (-)RGD
Sequence:
RefSeq Acc Id: XM_063272408   ⟹   XP_063128478
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81335,282,391 - 35,296,038 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001006997 (Get FASTA)   NCBI Sequence Viewer  
  XP_063128478 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH83919 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001006997   ⟸   NM_001006996
- UniProtKB: Q5XHY0 (UniProtKB/TrEMBL),   A6K809 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000038728   ⟸   ENSRNOT00000037203
RefSeq Acc Id: XP_063128478   ⟸   XM_063272408
- Peptide Label: isoform X1
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5XHY0-F1-model_v2 AlphaFold Q5XHY0 1-674 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698772
Promoter ID:EPDNEW_R9296
Type:initiation region
Name:Ddx18_1
Description:DEAD-box helicase 18
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01337,536,107 - 37,536,167EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1549712 AgrOrtholog
BioCyc Gene G2FUF-18496 BioCyc
Ensembl Genes ENSRNOG00000025430 Ensembl
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7135005 IMAGE-MGC_LOAD
InterPro DDX18/Has1_DEADc UniProtKB/TrEMBL
  DEAD-like_N UniProtKB/TrEMBL
  DNA/RNA_helicase_C UniProtKB/TrEMBL
  DNA/RNA_helicase_DEAD/DEAH_N UniProtKB/TrEMBL
  DUF4217 UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  RNA-helicase_DEAD-box_CS UniProtKB/TrEMBL
KEGG Report rno:308490 UniProtKB/TrEMBL
MGC_CLONE MGC:95311 IMAGE-MGC_LOAD
NCBI Gene 308490 ENTREZGENE
PANTHER ATP-DEPENDENT RNA HELICASE DDX18 UniProtKB/TrEMBL
  RNA HELICASE UniProtKB/TrEMBL
Pfam DEAD UniProtKB/TrEMBL
  DUF4217 UniProtKB/TrEMBL
  Helicase_C UniProtKB/TrEMBL
PhenoGen Ddx18 PhenoGen
PROSITE DEAD_ATP_HELICASE UniProtKB/TrEMBL
  HELICASE_ATP_BIND_1 UniProtKB/TrEMBL
  HELICASE_CTER UniProtKB/TrEMBL
RatGTEx ENSRNOG00000025430 RatGTEx
SMART DEXDc UniProtKB/TrEMBL
  DUF4217 UniProtKB/TrEMBL
  HELICc UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A6K809 ENTREZGENE, UniProtKB/TrEMBL
  Q5XHY0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-01-13 Ddx18  DEAD-box helicase 18  Ddx18  DEAD (Asp-Glu-Ala-Asp) box polypeptide 18  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Ddx18  DEAD (Asp-Glu-Ala-Asp) box polypeptide 18  MGC95311  similar to RIKEN cDNA 2310005B10  Symbol and Name updated 1299863 APPROVED
2005-09-15 MGC95311  similar to RIKEN cDNA 2310005B10      Symbol and Name status set to provisional 70820 PROVISIONAL