Abhd10 (abhydrolase domain containing 10, depalmitoylase)

Gene: Abhd10 (abhydrolase domain containing 10, depalmitoylase) Rattus norvegicus

Analyze

Symbol:

Abhd10

Name:

abhydrolase domain containing 10, depalmitoylase

RGD ID:

1308084

Description:

Predicted to enable hydrolase activity, hydrolyzing O-glycosyl compounds and palmitoyl-(protein) hydrolase activity. Predicted to be involved in glucuronoside catabolic process. Predicted to be located in cytosol. Predicted to be active in mitochondrion. Orthologous to human ABHD10 (abhydrolase domain containing 10, depalmitoylase); INTERACTS WITH 1,3-dinitrobenzene; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

abhydrolase domain containing 10; abhydrolase domain-containing protein 10, mitochondrial; acyl-protein thioesterase ABHD10; alpha/beta hydrolase domain-containing protein 10, mitochondrial; LOC103693563; LOC303953; mycophenolic acid acyl-glucuronide esterase, mitochondrial; palmitoyl-protein thioesterase ABHD10, mitochondrial; RGD1308084; similar to hypothetical protein FLJ11342

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	11	68,543,860 - 68,556,059 (+)	NCBI		GRCr8
mRatBN7.2	11	55,081,273 - 55,095,044 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	11	55,081,049 - 55,107,866 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	11	63,856,269 - 63,868,381 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	11	56,518,149 - 56,530,261 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	11	55,624,120 - 55,636,347 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	11	60,053,719 - 60,068,142 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	11	60,054,408 - 60,066,739 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0 Ensembl	11	57,486,365 - 57,498,894 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	11	60,649,036 - 60,661,684 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	11	56,568,757 - 56,580,881 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	11	56,626,350 - 56,638,144 (+)	NCBI
Celera	11	54,605,871 - 54,617,995 (+)	NCBI		Celera
Cytogenetic Map	11	q21	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(1->4)-beta-D-glucan (ISO)

1,3-dinitrobenzene (EXP)

1-chloro-2,4-dinitrobenzene (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

4,4'-sulfonyldiphenol (ISO)

4-(ethoxymethylene)-2-phenyloxazol-5-one (ISO)

6-propyl-2-thiouracil (EXP)

aflatoxin B1 (ISO)

all-trans-retinoic acid (EXP)

aristolochic acid A (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

Bisphenol B (ISO)

bisphenol F (ISO)

bleomycin A5 (ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

cobalt dichloride (EXP,ISO)

copper(II) sulfate (ISO)

cyclosporin A (ISO)

dicrotophos (ISO)

folic acid (ISO)

gentamycin (EXP)

ivermectin (ISO)

lipopolysaccharide (ISO)

methapyrilene (EXP)

methimazole (EXP)

methylmercury chloride (ISO)

nickel sulfate (ISO)

paracetamol (EXP)

perfluorooctane-1-sulfonic acid (ISO)

perfluorooctanoic acid (ISO)

pirinixic acid (ISO)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

sodium fluoride (ISO)

sulfadimethoxine (EXP)

sunitinib (ISO)

testosterone (ISO)

tolcapone (EXP)

valproic acid (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

glucuronoside catabolic process (IEA,ISO)

macromolecule depalmitoylation (IEA)

Cellular Component

cytosol (IEA,ISO)

mitochondrion (IBA,IEA,ISO,ISS)

Molecular Function

hydrolase activity, hydrolyzing O-glycosyl compounds (IBA,IEA,ISO)

mycophenolic acid acyl-glucuronide esterase activity (IEA)

palmitoyl-(protein) hydrolase activity (IBA,IEA,ISO,ISS)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA pipeline	RGD automated data pipeline
3.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
5.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:15489334	PMID:22294686

Genomics

Comparative Map Data

Abhd10
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	11	68,543,860 - 68,556,059 (+)	NCBI		GRCr8
mRatBN7.2	11	55,081,273 - 55,095,044 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	11	55,081,049 - 55,107,866 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	11	63,856,269 - 63,868,381 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	11	56,518,149 - 56,530,261 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	11	55,624,120 - 55,636,347 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	11	60,053,719 - 60,068,142 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	11	60,054,408 - 60,066,739 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0 Ensembl	11	57,486,365 - 57,498,894 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	11	60,649,036 - 60,661,684 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	11	56,568,757 - 56,580,881 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	11	56,626,350 - 56,638,144 (+)	NCBI
Celera	11	54,605,871 - 54,617,995 (+)	NCBI		Celera
Cytogenetic Map	11	q21	NCBI

ABHD10
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	111,979,026 - 111,993,368 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	111,979,010 - 111,993,368 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	3	111,697,873 - 111,712,215 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	113,180,589 - 113,194,896 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	3	113,180,588 - 113,194,896	NCBI
Celera	3	110,096,908 - 110,111,290 (+)	NCBI		Celera
Cytogenetic Map	3	q13.2	NCBI
HuRef	3	109,073,067 - 109,087,558 (+)	NCBI		HuRef
CHM1_1	3	111,661,769 - 111,676,256 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	3	114,700,126 - 114,714,476 (+)	NCBI		T2T-CHM13v2.0

Abhd10
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	16	45,550,088 - 45,563,355 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	16	45,550,088 - 45,563,318 (-)	Ensembl		GRCm39 Ensembl
GRCm38	16	45,729,725 - 45,742,955 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	16	45,729,725 - 45,742,955 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	16	45,730,510 - 45,743,019 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	16	45,649,729 - 45,662,236 (-)	NCBI		MGSCv36	mm8
Celera	16	46,107,096 - 46,119,396 (-)	NCBI		Celera
Cytogenetic Map	16	B5	NCBI
cM Map	16	30.04	NCBI

Abhd10
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955427	12,388,889 - 12,406,080 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955427	12,388,945 - 12,403,703 (+)	NCBI	ChiLan1.0	ChiLan1.0

ABHD10
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	2	109,978,556 - 109,993,272 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	3	109,983,340 - 109,998,052 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	109,123,202 - 109,137,879 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	116,046,993 - 116,061,816 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	116,046,993 - 116,061,816 (+)	Ensembl	panpan1.1		panPan2

ABHD10
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	33	16,618,085 - 16,631,084 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	33	16,617,466 - 16,630,211 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	33	16,719,976 - 16,733,005 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	33	16,856,025 - 16,869,091 (+)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	33	16,666,223 - 16,679,209 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	33	16,711,849 - 16,724,859 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	33	17,256,809 - 17,269,843 (+)	NCBI		UU_Cfam_GSD_1.0

Abhd10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	137,777,049 - 137,790,108 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936834	793,531 - 805,421 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936834	794,006 - 805,758 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ABHD10
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	147,759,763 - 147,775,891 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	13	147,760,742 - 147,778,072 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

ABHD10
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	22	68,804,259 - 68,818,561 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	22	68,802,251 - 68,818,722 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666041	97,656,080 - 97,671,217 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Abhd10
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624731	36,580,946 - 36,594,258 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624731	36,580,940 - 36,594,264 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Abhd10
200 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	189
Count of miRNA genes:	132
Interacting mature miRNAs:	144
Transcripts:	ENSRNOT00000048533
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1300147	Bp187	Blood pressure QTL 187	3.67		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	11	1	69446234	Rat
1558659	Tescar1	Testicular tumor resistance QTL 1	3.9		testis integrity trait (VT:0010572)	percentage of study population developing testis tumors during a period of time (CMO:0001261)	11	1041931	66113562	Rat
724554	Iddm17	Insulin dependent diabetes mellitus QTL 17		0.001	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	11	18976208	86241447	Rat
10058952	Gmadr6	Adrenal mass QTL 6	2.29	0.0072	adrenal gland mass (VT:0010420)	both adrenal glands wet weight to body weight ratio (CMO:0002411)	11	22959403	67959403	Rat
8694376	Bw156	Body weight QTL 156	2.25	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	11	23280456	68280456	Rat
9590313	Scort20	Serum corticosterone level QTL 20	6.51	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	11	23280456	68280456	Rat
9589032	Epfw10	Epididymal fat weight QTL 10	9.29	0.001	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	11	23280456	68280456	Rat
8694424	Bw162	Body weight QTL 162	3.8	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	11	23280456	68280456	Rat
724563	Uae10	Urinary albumin excretion QTL 10	6		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	11	27672410	82846715	Rat
1300130	Rf20	Renal function QTL 20	4.44		kidney glomerulus integrity trait (VT:0010546)	kidney glomerulus diameter (CMO:0001166)	11	29528418	60324829	Rat
1300110	Stl7	Serum triglyceride level QTL 7	4.64		blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	11	29528418	82566702	Rat
2298551	Neuinf10	Neuroinflammation QTL 10	3.7		nervous system integrity trait (VT:0010566)	spinal cord beta-2 microglobulin mRNA level (CMO:0002125)	11	31239134	78851519	Rat
70180	BpQTLcluster10	Blood pressure QTL cluster 10	3.19		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	11	34918041	79918041	Rat
1300135	Rf19	Renal function QTL 19	3.38		blood creatinine amount (VT:0005328)	creatinine clearance (CMO:0000765)	11	40946188	82566702	Rat
2312566	Glom20	Glomerulus QTL 20	3.6	0.001	kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	11	44285759	82566702	Rat
1581565	Pur10	Proteinuria QTL 10		0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	11	44803318	82846466	Rat
1581572	Uae35	Urinary albumin excretion QTL 35		0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	11	44803318	82846466	Rat
4889859	Pur28	Proteinuria QTL 28	19.5	0.001	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	11	45459323	75190161	Rat
724561	Plsm4	Polydactyly-luxate syndrome (PLS) morphotypes QTL 4		0.0003	forelimb integrity trait (VT:0010562)	front foot phalanges count (CMO:0001947)	11	54457534	86241447	Rat

Markers in Region

RH130147

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	11	55,093,269 - 55,093,420 (+)	MAPPER	mRatBN7.2
Rnor_6.0	11	60,066,366 - 60,066,516	NCBI	Rnor6.0
Rnor_6.0	11	57,498,700 - 57,498,850	NCBI	Rnor6.0
Rnor_5.0	11	60,661,468 - 60,661,618	UniSTS	Rnor5.0
RGSC_v3.4	11	56,580,687 - 56,580,837	UniSTS	RGSC3.4
Celera	11	54,617,801 - 54,617,951	UniSTS
Cytogenetic Map	11	q21	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium
Low	1	38	29	15	16	15	3	3	72	25	37	9	3
Below cutoff	2	5	27	25	3	25	5	8	2	9	3	2	5

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001123352	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008768732	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC108574	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC088235	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC161919	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000011	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000048533 ⟹ ENSRNOP00000043990

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	11	57,486,365 - 57,498,894 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000086393 ⟹ ENSRNOP00000075644

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	11	57,486,775 - 57,498,568 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000091756 ⟹ ENSRNOP00000071368

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	11	55,081,049 - 55,107,866 (+)	Ensembl
Rnor_6.0 Ensembl	11	60,054,408 - 60,066,739 (+)	Ensembl

RefSeq Acc Id:

NM_001123352 ⟹ NP_001116824

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	11	68,543,935 - 68,556,059 (+)	NCBI
mRatBN7.2	11	55,081,340 - 55,093,464 (+)	NCBI
Rnor_6.0	11	60,054,436 - 60,066,560 (+)	NCBI
Rnor_5.0	11	60,649,036 - 60,661,684 (+)	NCBI
RGSC_v3.4	11	56,568,757 - 56,580,881 (+)	RGD
Celera	11	54,605,871 - 54,617,995 (+)	RGD

Sequence:

show sequence

GGAAGATGGCTGCCTGGGTACCTTGTCGGAAGTGGGGCTGGGCGGCTGTGTCCTTCGGCCGGCA
CCGAGGCCTGATCGCGTCACTTGCTCGGAAGCCCCCATGGGCATGGTGGCTCTCAGCTTGCAGA
CAAAAGACAACACTCTCTTTCCTTAAACGACCAGAACTTCCAAGCCTGGCTTATAAGAGGTTAA
AGGGCAAAAACCCAGGAATTATCTTCATCCCTGGTTATCTTTCTAACATGAATGGTAAAAAGGC
AGTAGCGATTGAGGAGTTTTGCAAATCTATAGGTCACGCCTTTATCAGGTTTGACTACTCTGGG
GTTGGAAGCTCAGATGGTAACTTAGCAGAGTGCTCAGTGGGGAAGTGGAGAAAGGATGTTCTTT
CCATCCTTGATGATATAGCCGAAGGACCACAGATACTGGTTGGATCCAGCCTTGGTGGATGGCT
CATGCTGCATGCTGCAATTGCACGGCCAGAGAAGGTCATAGCTCTTATTGGGATAGCTTCTGCT
ACAGATGGAGTGGTGACACAGTTTCACTCACTTCCCGTTGAGATGCAAAAGGAAATAGAAATGA
AAGGTGAATGGTCCTTGCCATCAAAATACAACAAAGAAGGCTATTACAGCATTCCTTACAGTTT
CATTAAAGAGGCGGCGCATCACTGCTTGTTACACAGCCCCATTCCTGTGACGTGCCCTGTACGG
TTGCTCCACGGCATGAAGGACGAAATAGTTCCTTGGCACAGATCCCTGCAGGTTGCCGACCGAG
TAGTCAGCCCAGATGTGGATGTCATCCTCCGGAAGCACAGTGATCACAGGATGAAGGAGACAGC
AGATATCCATCTGCTTATCTGTACTATTGATGACTTGATTGACAAGCTTTCAACTGTGACTCAC
TAGAACCGCACTTGTGCTTGGTGTGCACTCTAGTGCGTCCAGAAGATTGAAAGGATGGTAGTAA
ATCAAAGACCCGGGTACTTCAGGGTTTCCCCTTCTAGTATGTAAATATCCGATACGTATTTATT
TAATGATGTGTTTGCACAAGTACACAAATTGGGAGAAAAATATTAGCTGCTGTTTGGAAATTTT
TGTCCTCCTTTGATATTTTTCCCATTAAAATAGTACCTATTTTTTTTATTAAAGAGATGTTTAC
CTTTCTTATGTACACTTTAGCTGTGCCAGCTCTCAATTGTGTTCCTTTCTTCTACAATAAAGCT
TGAATAGTTAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_008768732 ⟹ XP_008766954

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	11	68,543,860 - 68,555,523 (+)	NCBI
mRatBN7.2	11	55,081,273 - 55,095,044 (+)	NCBI
Rnor_6.0	11	60,053,719 - 60,068,142 (+)	NCBI

Sequence:

show sequence

TCTTTTACTCCCTGCCCTTTGTGTCTGTGGGACAAATCTCTATGTGGTGGGAACTTGGTCTAGG
GGTCCCTTCAGTGTTCTTTTTATTTAGGATAGTCATAAAAGGAATGGTAGTTCAAAGAGTACTG
AAAAGTATGTGCATAATAAACAAACATGGCCAGATTGCCTGACAAAAGACTTTAGGTTTTCACC
CATAGAGCAACCATATGTGAATGAGTGTTTTCAGTACTTTTACTTGTGGCTGCTCATTTGAATG
TTTAGCAATCTGGTGAGTGGGAAAATGTTTGGGAGAGAGCAAAGAATGTTTGATGCGACTCCAA
TAATGTGACTGGCCTCTTGAATTTTTACCCCCATAGGAGTAATCAAAGAAGCCTAGCAAATTTT
ATCACAGGTCTTTGGGTCCTCCGGATGGTAACACGGTTTCCCATTTACAAACGCTCCATTTGAC
CATAGCTCCTCTCTGAGATTTCTGCAGCTTACTGCGATGAAAAACGGCCAAGGACGCCTAATGT
CACAAGCCAAATGCCCTTTGGGGTACACAGAACAAACTAGTCGAGACAGCCACACGCCAGACAG
CACCCTTGCGCATGCGTCTCCTCGGGAGAAACAAATCCCACGTGATGCAAGTTAGCAACCTCCG
CCTTCCTGCGGACTGCGCGTGCGTGACCTCGGGACCGCGCGACCGGTGCACGTCTGTAGCGGGC
GCAGGGGTAGCTGGGAAGATGGCTGCCTGGGTACCTTGTCGGAAGTGGGGCTGGGCGGCTGTGT
CCTTCGGCCGGCACCGAGGCCTGATCGCGTCACTTGCTCGGAAGCCCCCATGGGCATGGTGGCT
CTCAGCTTGCAGACAAAAGACAACACTCTCTTTCCTTAAACGACCAGAACTTCCAAGCCTGGCT
TATAAGAGGTTAAAGGGCAAAAACCCAGGAATTATCTTCATCCCTGGTTATCTTTCTAACATGA
ATGGTAAAAAGGCAGTAGCGATTGAGGAGTTTTGCAAATCTATAGGTCACGCCTTTATCAGGTT
TGACTACTCTGGGGTTGGAAGCTCAGATGGTAACTTAGCAGAGTGCTCAGTGGGGAAGTGGAGA
AAGGATGTTCTTTCCATCCTTGATGATATAGCCGAAGGACCACAGATACTGGTTGGATCCAGCC
TTGGTGGATGGCTCATGCTGCATGCTGCAATTGCACGGCCAGAGAAGGTCATAGCTCTTATTGG
GATAGCTTCTGCTACAGATGGAGTGGTGACACAGTTTCACTCACTTCCCGTTGAGTGGACCATG
TTCCTGAGAAATGTCAACCAAGGTGCACAGTGATACACACAAATTCACCTCATGAGAGTCCTGA
TGTTTTTTCCTGTCAGAGATGCAAAAGGAAATAGAAATGAAAGGTGAATGGTCCTTGCCATCAA
AATACAACAAAGAAGGCTATTACAGCATTCCTTACAGTTTCATTAAAGAGGCGGCGCATCACTG
CTTGTTACACAGCCCCATTCCTGTGACGTGCCCTGTACGGTTGCTCCACGGCATGAAGGACGAA
ATAGTTCCTTGGCACAGATCCCTGCAGGTTGCCGACCGAGTAGTCAGCCCAGATGTGGATGTCA
TCCTCCGGAAGCACAGTGATCACAGGATGAAGGAGACAGCAGATATCCATCTGCTTATCTGTAC
TATTGATGACTTGATTGACAAGCTTTCAACTGTGACTCACTAGAACCGCACTTGTGCTTGGTGT
GCACTCTAGTGCGTCCAGAAGATTGAAAGGATGGTAGTAAATCAAAGACCCGGGTACTTCAGGG
TTTCCCCTTCTAGTATGTAAATATCCGATACGTATTTATTTAATGATGTGTTTGCACAAGTACA
CAAATTGGGAGAAAAATATTAGCTGCTGTTTGGAAATTTTTGTCCTCCTTTGATATTTTTCCCA
TTAAAATAGTACCTATTTTTTTTATTAAAGAGATGTTTACCTTTCTTATGTACACTTTAGCTGT
GCCAGCTCTCAATTGTGTTCCTTTCTTCTACAATAAAGCTTGAATAGTTTGGGTTTTGTCTGGT
ACCATTATATATGGAGGTTTGTAAAATTCTGCTTTTAAAATACAATTCAGAAAATAGAGGAGGA
TTTTATTCAAGTAATATGAAATGATTATTGAAATGTCTGAAGCATGATAAAGTTGGGAAAATGA
GAGTGCCATGCTATATTTAAAACTAAAATTACTGTTTAATTATTTTAAAGGTTAAGTTTTATTG
TGATGTAAAAGATACTTTTAAATTTTAAATTGTCATTCTTATGGGAGTCTTCCAGAATTTTTAA
TTTTTTTAAGTTTATATGTAAAATAATAGGTAATATAATTTCCAACACTTCTTTCATTTTATCC
TTGAACCTCACTTACACATATCCTCTGCTGTGTCTCTCATTCTCTGCTTCCCCCACACCCTTTT
TCTCCCCGCAGTCCCCTTCTGCTTTCATGCTATGTCTCTGTATGAAAAAACATAGCTACTATTT
CCCTTCCCCACCGCTGCCCTTTCATGCTCCCCTAACATCCTTTAGAGCCTTCTCTGCAGTCTAC
TTTCTCCAGCCATGCAATATGTGTATTTAAGTCTGTATTCTACATATGAGAGAAAACACTTTCC
ACATCCAATCGGTTTCTCTTTACAGCATCTCAGTTCCACCATTTTCCTGCAAACATGCCTTATA
GTTAAATGGTATACATGTAATGGTGTAGTAATTTTATATAATGATTGGTTAGATTAAAGAGAGA
GATGATCTTTCTGCATTAACCCTGCTTTGGGGAATACGATTAGAGTGGCTTAAGTGCAAGTAGT
TGGGTGGTTACCACTTTAGTCTGAGTGGCAGAAGGGTAGAGTCAGTAAGGAAACATGAAATGCT
AGTATAAGGCATGGCATCTAATAACTACTGAGGTATTAATGTATACTAGCCTTTATATTAAATT
GTGGTTTGTTCTTTAGTTATTAATTTTGGCTAGACGTTAGCCTTCATGGGTTATATCTGTCTAT
GTTAAGGTGACAAGATAACTCATAAAATGTGTCGAAGACTTAATTGATGTCATAAACGAGAGTC
AGCAGACAATAAACCTGGTTGAAAGGACAGTTTAAGAAACATAGTATTTATAGCCCATGAAGAA
AAGGGTGATAAAATTTCTGTGCAGGAAAGTGTTGCAGCTGGTTGGCAGATCATCCTGAGAAACA
TTCCTTATGACTTGGCTTTTGTCTGTCTGGGAACTTGGATTTCAGGGACTCCCACTATGGCCAG
AAATGAGACTAGTAGCTCACTGTGCATAGTCAACTCTGCAAACACTGGTTTATGCTTAACCTGG
CTTTCTTCCCTGGTGCCCAGAATGTTGATATATGTGGATCAGAGATTACCTCTGAATAGTCCAG
TAAAACCCCTTGGTACCGCCTCTTAACAAGCTTTCTTGTGGATGCTATCACATGAGCTGTTAGA
GCTCTTTGCTGGAGACCCAGTTTTGGCCTGTGTGACTTCAGTGTGGATTCTTGGAAGCTTACCC
CCAGTTTCCCTGGGCTTCACCCCATGTGCCTTTTTCCTTTGCTCACTCTGCTTTGGATCCGTTC
ACTCTAATAAATCAGTAGTGAAAGAACTGTA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001116824	(Get FASTA)	NCBI Sequence Viewer
	XP_008766954	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH88235	(Get FASTA)	NCBI Sequence Viewer
	AAI61919	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000071368
	ENSRNOP00000071368.2
GenBank Protein	Q5I0K5	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_001116824 ⟸ NM_001123352
- Peptide Label:	precursor
- UniProtKB:	Q5I0K5 (UniProtKB/Swiss-Prot), B1WBW9 (UniProtKB/TrEMBL), A6IQX5 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAAWVPCRKWGWAAVSFGRHRGLIASLARKPPWAWWLSACRQKTTLSFLKRPELPSLAYKRLKG KNPGIIFIPGYLSNMNGKKAVAIEEFCKSIGHAFIRFDYSGVGSSDGNLAECSVGKWRKDVLSI LDDIAEGPQILVGSSLGGWLMLHAAIARPEKVIALIGIASATDGVVTQFHSLPVEMQKEIEMKG EWSLPSKYNKEGYYSIPYSFIKEAAHHCLLHSPIPVTCPVRLLHGMKDEIVPWHRSLQVADRVV SPDVDVILRKHSDHRMKETADIHLLICTIDDLIDKLSTVTH hide sequence

RefSeq Acc Id:

XP_008766954 ⟸ XM_008768732

- Peptide Label:

isoform X1

- Sequence:

show sequence

MRLLGRNKSHVMQVSNLRLPADCACVTSGPRDRCTSVAGAGVAGKMAAWVPCRKWGWAAVSFGR
HRGLIASLARKPPWAWWLSACRQKTTLSFLKRPELPSLAYKRLKGKNPGIIFIPGYLSNMNGKK
AVAIEEFCKSIGHAFIRFDYSGVGSSDGNLAECSVGKWRKDVLSILDDIAEGPQILVGSSLGGW
LMLHAAIARPEKVIALIGIASATDGVVTQFHSLPVEWTMFLRNVNQGAQ

hide sequence

RefSeq Acc Id:

ENSRNOP00000071368 ⟸ ENSRNOT00000091756

RefSeq Acc Id:

ENSRNOP00000043990 ⟸ ENSRNOT00000048533

RefSeq Acc Id:

ENSRNOP00000075644 ⟸ ENSRNOT00000086393

Protein Domains

AB hydrolase-1

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q5I0K5-F1-model_v2	AlphaFold	Q5I0K5	1-297	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13698130

Promoter ID:

EPDNEW_R8655

Type:

multiple initiation site

Name:

LOC103693563_1

Description:

mycophenolic acid acyl-glucuronide esterase, mitochondrial

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	11	60,054,431 - 60,054,491	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1308084	AgrOrtholog
BioCyc Gene	G2FUF-21386	BioCyc
Ensembl Genes	ENSRNOG00000043107	Ensembl
	ENSRNOG00000054334	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000091756	ENTREZGENE
	ENSRNOT00000091756.2	UniProtKB/TrEMBL
Gene3D-CATH	3.40.50.1820	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7324996	IMAGE-MGC_LOAD
	IMAGE:8369987	IMAGE-MGC_LOAD
InterPro	AB_hydrolase	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	AB_hydrolase_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:303953	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE	MGC:109004	IMAGE-MGC_LOAD
	MGC:187658	IMAGE-MGC_LOAD
NCBI Gene	303953	ENTREZGENE
PANTHER	MYCOPHENOLIC ACID ACYL-GLUCURONIDE ESTERASE, MITOCHONDRIAL	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PALMITOYL-PROTEIN THIOESTERASE ABHD10, MITOCHONDRIAL	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	Abhydrolase_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Abhd10	PhenoGen
RatGTEx	ENSRNOG00000043107	RatGTEx
	ENSRNOG00000054334	RatGTEx
Superfamily-SCOP	SSF53474	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A8L2R3X6_RAT	UniProtKB/TrEMBL
	A6IQX5	ENTREZGENE, UniProtKB/TrEMBL
	ABHDA_RAT	UniProtKB/Swiss-Prot
	B1WBW9	ENTREZGENE, UniProtKB/TrEMBL
	Q5I0K5	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2021-03-09	Abhd10	abhydrolase domain containing 10, depalmitoylase	LOC103693563	mycophenolic acid acyl-glucuronide esterase, mitochondrial	Data merged from RGD:9356323	737654	PROVISIONAL
2020-02-13	Abhd10	abhydrolase domain containing 10, depalmitoylase	Abhd10	abhydrolase domain containing 10	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2014-08-25	LOC103693563	mycophenolic acid acyl-glucuronide esterase, mitochondrial			Symbol and Name status set to provisional	70820	PROVISIONAL
2008-02-26	Abhd10	abhydrolase domain containing 10	RGD1308084	similar to hypothetical protein FLJ11342	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-12-06	RGD1308084	similar to hypothetical protein FLJ11342	RGD1308084_predicted	similar to hypothetical protein FLJ11342 (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-20	RGD1308084_predicted	similar to hypothetical protein FLJ11342 (predicted)	LOC303953_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC303953_predicted	similar to hypothetical protein FLJ11342 (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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