Imported Disease Annotations - CTDTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | amyotrophic lateral sclerosis type 21 | | ISO | MATR3 (Homo sapiens) | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | | |
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Imported Disease Annotations - CTDTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | amyotrophic lateral sclerosis type 21 | | ISO | MATR3 (Homo sapiens) | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | | |
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# | Reference Title | Reference Citation |
1. | Molecular cloning of matrin 3. A 125-kilodalton protein of the nuclear matrix contains an extensive acidic domain. | Belgrader P, etal., J Biol Chem 1991 May 25;266(15):9893-9. |
2. | Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
3. | Rat ISS GO annotations from GOA human gene data--August 2006 | GOA data from the GO Consortium |
4. | Molecular properties and intracellular localization of rat liver nuclear scaffold protein P130. | Hibino Y, etal., Biochim Biophys Acta. 2006 May;1759(5):195-207. Epub 2006 May 22. |
5. | Electronic Transfer of LocusLink and RefSeq Data | NCBI rat LocusLink and RefSeq merged data July 26, 2002 |
6. | OMIM Disease Annotation Pipeline | OMIM Disease Annotation Pipeline |
7. | GOA pipeline | RGD automated data pipeline |
8. | ClinVar Automated Import and Annotation Pipeline | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
9. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
10. | Comprehensive gene review and curation | RGD comprehensive gene curation |
11. | Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. | Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11. |
12. | Tentative Sequence Identification Numbers | Tentative Sequence Data IDs. TIGR Gene Index, Rat Data |
PMID:1575753 | PMID:8250943 | PMID:8357833 | PMID:9111204 | PMID:9524232 | PMID:10860485 | PMID:11112453 | PMID:16396499 | PMID:16641100 | PMID:19946888 | PMID:21771347 | PMID:22082260 |
PMID:22658674 | PMID:22681889 | PMID:22871113 | PMID:24625528 | PMID:25416956 | PMID:25574029 | PMID:27869233 | PMID:28431233 | PMID:28712728 | PMID:28755400 | PMID:29476059 | PMID:30597036 |
PMID:35736640 |
Matr3 (Rattus norvegicus - Norway rat) |
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MATR3 (Homo sapiens - human) |
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Matr3 (Mus musculus - house mouse) |
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Matr3 (Chinchilla lanigera - long-tailed chinchilla) |
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MATR3 (Pan paniscus - bonobo/pygmy chimpanzee) |
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MATR3 (Canis lupus familiaris - dog) |
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Matr3 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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MATR3 (Sus scrofa - pig) |
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MATR3 (Chlorocebus sabaeus - green monkey) |
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Matr3 (Heterocephalus glaber - naked mole-rat) |
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Variants in Matr3
153 total Variants |
The detailed report is available here: | Full Report | CSV | TAB | Printer | ||||
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
The following QTLs overlap with this region. | Full Report | CSV | TAB | Printer | Gviewer |
alimentary part of gastrointestinal system | circulatory system | endocrine system | exocrine system | hemolymphoid system | hepatobiliary system | integumental system | musculoskeletal system | nervous system | renal system | reproductive system | respiratory system | appendage | |
High | |||||||||||||
Medium | 3 | 42 | 57 | 41 | 19 | 41 | 8 | 10 | 74 | 35 | 41 | 11 | 8 |
Low | 1 | 1 | |||||||||||
Below cutoff |
RefSeq Transcripts | NM_019149 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
XM_006254534 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_017600886 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_017600887 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063277175 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063277176 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063277177 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063277178 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063277179 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063277180 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063277181 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063277182 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063277183 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063277184 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063277185 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063277186 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063277187 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
GenBank Nucleotide | AB205483 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
AC135285 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
BC062231 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
BC168723 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
CH473974 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
FQ213524 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
FQ225101 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
FQ227851 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
FQ230646 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
FQ233097 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
FQ234052 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
FQ234627 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
FQ235016 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
JAXUCZ010000018 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
LC420149 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
M63485 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
RefSeq Acc Id: | ENSRNOT00000026949 ⟹ ENSRNOP00000026949 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | ENSRNOT00000083993 ⟹ ENSRNOP00000073436 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | NM_019149 ⟹ NP_062022 | ||||||||||||||||||||||||||||
RefSeq Status: | VALIDATED | ||||||||||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_006254534 ⟹ XP_006254596 | ||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_017600886 ⟹ XP_017456375 | ||||||||||||||||
Type: | CODING | ||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_017600887 ⟹ XP_017456376 | ||||||||||||||||
Type: | CODING | ||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_063277175 ⟹ XP_063133245 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063277176 ⟹ XP_063133246 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063277177 ⟹ XP_063133247 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063277178 ⟹ XP_063133248 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063277179 ⟹ XP_063133249 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063277180 ⟹ XP_063133250 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063277181 ⟹ XP_063133251 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063277182 ⟹ XP_063133252 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063277183 ⟹ XP_063133253 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063277184 ⟹ XP_063133254 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063277185 ⟹ XP_063133255 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063277186 ⟹ XP_063133256 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063277187 ⟹ XP_063133257 | ||||||||
Type: | CODING | ||||||||
Position: |
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Protein RefSeqs | NP_062022 | (Get FASTA) | NCBI Sequence Viewer |
XP_006254596 | (Get FASTA) | NCBI Sequence Viewer | |
XP_017456375 | (Get FASTA) | NCBI Sequence Viewer | |
XP_017456376 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063133245 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063133246 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063133247 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063133248 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063133249 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063133250 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063133251 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063133252 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063133253 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063133254 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063133255 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063133256 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063133257 | (Get FASTA) | NCBI Sequence Viewer | |
GenBank Protein | AAB63955 | (Get FASTA) | NCBI Sequence Viewer |
AAH62231 | (Get FASTA) | NCBI Sequence Viewer | |
AAI68723 | (Get FASTA) | NCBI Sequence Viewer | |
BAD90681 | (Get FASTA) | NCBI Sequence Viewer | |
EDL76258 | (Get FASTA) | NCBI Sequence Viewer | |
Ensembl Protein | ENSRNOP00000026949 | ||
ENSRNOP00000026949.3 | |||
GenBank Protein | P43244 | (Get FASTA) | NCBI Sequence Viewer |
RefSeq Acc Id: | NP_062022 ⟸ NM_019149 |
- UniProtKB: | Q5DVW1 (UniProtKB/Swiss-Prot), O35833 (UniProtKB/Swiss-Prot), P43244 (UniProtKB/Swiss-Prot), A0A0G2JSR7 (UniProtKB/TrEMBL), A6J2X6 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | XP_006254596 ⟸ XM_006254534 |
- Peptide Label: | isoform X2 |
- UniProtKB: | Q5DVW1 (UniProtKB/Swiss-Prot), O35833 (UniProtKB/Swiss-Prot), P43244 (UniProtKB/Swiss-Prot), A0A0G2JSR7 (UniProtKB/TrEMBL), A6J2X6 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | XP_017456375 ⟸ XM_017600886 |
- Peptide Label: | isoform X2 |
- UniProtKB: | Q5DVW1 (UniProtKB/Swiss-Prot), O35833 (UniProtKB/Swiss-Prot), P43244 (UniProtKB/Swiss-Prot), A0A0G2JSR7 (UniProtKB/TrEMBL), A6J2X6 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | XP_017456376 ⟸ XM_017600887 |
- Peptide Label: | isoform X2 |
- UniProtKB: | Q5DVW1 (UniProtKB/Swiss-Prot), O35833 (UniProtKB/Swiss-Prot), P43244 (UniProtKB/Swiss-Prot), A0A0G2JSR7 (UniProtKB/TrEMBL), A6J2X6 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | ENSRNOP00000026949 ⟸ ENSRNOT00000026949 |
RefSeq Acc Id: | ENSRNOP00000073436 ⟸ ENSRNOT00000083993 |
RefSeq Acc Id: | XP_063133250 ⟸ XM_063277180 |
- Peptide Label: | isoform X1 |
RefSeq Acc Id: | XP_063133245 ⟸ XM_063277175 |
- Peptide Label: | isoform X1 |
RefSeq Acc Id: | XP_063133257 ⟸ XM_063277187 |
- Peptide Label: | isoform X4 |
RefSeq Acc Id: | XP_063133255 ⟸ XM_063277185 |
- Peptide Label: | isoform X3 |
- UniProtKB: | A6J2Y0 (UniProtKB/TrEMBL) |
RefSeq Acc Id: | XP_063133256 ⟸ XM_063277186 |
- Peptide Label: | isoform X3 |
- UniProtKB: | A6J2Y0 (UniProtKB/TrEMBL) |
RefSeq Acc Id: | XP_063133246 ⟸ XM_063277176 |
- Peptide Label: | isoform X1 |
RefSeq Acc Id: | XP_063133252 ⟸ XM_063277182 |
- Peptide Label: | isoform X2 |
- UniProtKB: | A0A0G2JSR7 (UniProtKB/TrEMBL), A6J2X6 (UniProtKB/TrEMBL) |
RefSeq Acc Id: | XP_063133251 ⟸ XM_063277181 |
- Peptide Label: | isoform X1 |
RefSeq Acc Id: | XP_063133248 ⟸ XM_063277178 |
- Peptide Label: | isoform X1 |
RefSeq Acc Id: | XP_063133254 ⟸ XM_063277184 |
- Peptide Label: | isoform X2 |
- UniProtKB: | A0A0G2JSR7 (UniProtKB/TrEMBL), A6J2X6 (UniProtKB/TrEMBL) |
RefSeq Acc Id: | XP_063133253 ⟸ XM_063277183 |
- Peptide Label: | isoform X2 |
- UniProtKB: | A0A0G2JSR7 (UniProtKB/TrEMBL), A6J2X6 (UniProtKB/TrEMBL) |
RefSeq Acc Id: | XP_063133247 ⟸ XM_063277177 |
- Peptide Label: | isoform X1 |
RefSeq Acc Id: | XP_063133249 ⟸ XM_063277179 |
- Peptide Label: | isoform X1 |
Name | Modeler | Protein Id | AA Range | Protein Structure |
AF-P43244-F1-model_v2 | AlphaFold | P43244 | 1-845 | view protein structure |
eQTL | View at Phenogen | |
WGCNA | View at Phenogen | |
Tissue/Strain Expression | View at Phenogen |
RGD ID: | 13700708 | ||||||||
Promoter ID: | EPDNEW_R11231 | ||||||||
Type: | initiation region | ||||||||
Name: | Matr3_1 | ||||||||
Description: | matrin 3 | ||||||||
SO ACC ID: | SO:0000170 | ||||||||
Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | ||||||||
Experiment Methods: | Single-end sequencing. | ||||||||
Position: |
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Database | Acc Id | Source(s) |
AGR Gene | RGD:3052 | AgrOrtholog |
BioCyc Gene | G2FUF-7909 | BioCyc |
Ensembl Genes | ENSRNOG00000019875 | Ensembl, ENTREZGENE, UniProtKB/TrEMBL |
Ensembl Transcript | ENSRNOT00000026949.6 | UniProtKB/TrEMBL |
Gene3D-CATH | 3.30.70.330 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
IMAGE_CLONE | IMAGE:6921221 | IMAGE-MGC_LOAD |
InterPro | MATR3_RRM1 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
MATR3_RRM2 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Matrin/U1-C_Znf_C2H2 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Matrin/U1-like-C_Znf_C2H2 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Nucleotide-bd_a/b_plait_sf | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
RBD_domain_sf | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
RRM_dom | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
KEGG Report | rno:29150 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
MGC_CLONE | MGC:72856 | IMAGE-MGC_LOAD |
NCBI Gene | 29150 | ENTREZGENE |
PANTHER | MATRIN 3/NUCLEAR PROTEIN 220-RELATED | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
MATRIN-3 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Pfam | RRM_5 | UniProtKB/TrEMBL |
PhenoGen | Matr3 | PhenoGen |
PROSITE | RRM | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
ZF_MATRIN | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
RatGTEx | ENSRNOG00000019875 | RatGTEx |
SMART | RRM | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
ZnF_U1 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Superfamily-SCOP | SSF54928 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
TIGR | TC217434 | |
UniProt | A0A0G2JSR7 | ENTREZGENE, UniProtKB/TrEMBL |
A6J2X6 | ENTREZGENE, UniProtKB/TrEMBL | |
A6J2Y0 | ENTREZGENE, UniProtKB/TrEMBL | |
B5DEM0_RAT | UniProtKB/TrEMBL | |
MATR3_RAT | UniProtKB/Swiss-Prot | |
O35833 | ENTREZGENE | |
P43244 | ENTREZGENE | |
Q5DVW1 | ENTREZGENE | |
Q6P6H1_RAT | UniProtKB/TrEMBL | |
UniProt Secondary | O35833 | UniProtKB/Swiss-Prot |
Q5DVW1 | UniProtKB/Swiss-Prot |
Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
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2002-06-10 | Matr3 | matrin 3 | Name updated | 70584 | APPROVED |
Note Type | Note | Reference |
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gene_domains | contains a highly acidic domain and a putative nuclear targeting signal sequence | 69882 |