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ONTOLOGY REPORT - ANNOTATIONS

Term:inositol phosphate biosynthetic process
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Accession:GO:0032958 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached.
Synonyms:exact_synonym: inositol phosphate anabolism;   inositol phosphate biosynthesis;   inositol phosphate formation;   inositol phosphate synthesis
 narrow_synonym: myo-inositol phosphate biosynthetic process


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inositol phosphate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ip6k1 inositol hexakisphosphate kinase 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:108,693,068...108,737,278 JBrowse link
G Ip6k2 inositol hexakisphosphate kinase 2 involved_in IEA
IBA
ISO		 GO_REF:0000002
GO_REF:0000033
MGI:5635272 (PMID:24657168)
GO_REF:0000107		 InterPro
GO_Central
RGD
Ensembl		 PMID:24657168 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:109,483,843...109,510,172
Ensembl chr 8:109,484,310...109,510,166 		JBrowse link
G Ip6k3 inositol hexakisphosphate kinase 3 acts_upstream_of_or_within
involved_in		 ISO
IBA		 (PMID:11502751)
GO_REF:0000033		 RGD
GO_Central		 PMID:11502751 GO_REF:0000033 NCBI chr20:5,223,863...5,245,443
Ensembl chr20:5,224,120...5,245,428 		JBrowse link
G Ipmk inositol polyphosphate multikinase involved_in
acts_upstream_of_or_within		 IEA
IBA
ISO		 GO_REF:0000002
GO_REF:0000033
MGI:3583918 (PMID:15939867)		 InterPro
GO_Central
RGD		 PMID:15939867 GO_REF:0000002 GO_REF:0000033 NCBI chr20:17,216,988...17,251,675
Ensembl chr20:17,218,037...17,251,705 		JBrowse link
G Ippk inositol-pentakisphosphate 2-kinase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:15,190,191...15,235,203
Ensembl chr17:15,190,265...15,229,541 		JBrowse link
G Itpka inositol-trisphosphate 3-kinase A involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:106,726,036...106,734,601
Ensembl chr 3:106,726,036...106,734,600 		JBrowse link
G Itpkb inositol-trisphosphate 3-kinase B involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr13:92,069,160...92,164,281
Ensembl chr13:92,069,216...92,162,004 		JBrowse link
G Itpkc inositol-trisphosphate 3-kinase C involved_in IEA
IBA		 GO_REF:0000002
GO_REF:0000033		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr 1:82,500,957...82,522,533
Ensembl chr 1:82,500,957...82,522,779 		JBrowse link
G Ppip5k1 diphosphoinositol pentakisphosphate kinase 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:108,284,120...108,327,683
Ensembl chr 3:108,284,120...108,323,428 		JBrowse link
inositol trisphosphate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plcg1 phospholipase C, gamma 1 IMP RGD PMID:16973916 RGD:2299886 NCBI chr 3:149,385,587...149,416,330
Ensembl chr 3:149,385,587...149,416,330 		JBrowse link
G Plcg2 phospholipase C, gamma 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:9013981)		 Ensembl
RGD		 PMID:9013981 GO_REF:0000107 NCBI chr19:45,547,416...45,683,930
Ensembl chr19:45,547,416...45,683,930 		JBrowse link
G Pou1f1 POU class 1 homeobox 1 acts_upstream_of ISO MGI:1856024|MGI:1856025 (PMID:11371619) RGD PMID:11371619 NCBI chr11:3,316,818...3,334,804
Ensembl chr11:3,317,058...3,334,801 		JBrowse link
G Ptafr platelet-activating factor receptor acts_upstream_of_or_within ISO (PMID:9013981) RGD PMID:9013981 NCBI chr 5:144,765,770...144,795,057
Ensembl chr 5:144,765,976...144,795,251 		JBrowse link
G Scp2 sterol carrier protein 2 involved_in ISO (PMID:12641450) RGD PMID:12641450 NCBI chr 5:122,806,949...122,881,259
Ensembl chr 5:122,776,549...122,881,287 		JBrowse link
negative regulation of inositol phosphate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plek pleckstrin involved_in ISO (PMID:7559487), (PMID:7782310) RGD PMID:7559487 PMID:7782310 NCBI chr14:91,397,015...91,429,693
Ensembl chr14:91,397,019...91,454,131 		JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 IMP RGD PMID:7535379 RGD:7777104 NCBI chr 1:228,409,605...229,638,794
Ensembl chr 1:228,408,947...229,639,080 		JBrowse link
positive regulation of inositol phosphate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcyap1r1 ADCYAP receptor type I IDA RGD PMID:8943280 RGD:2315982 NCBI chr 4:84,593,558...84,642,700
Ensembl chr 4:84,593,892...84,642,700 		JBrowse link
G Avpr1b arginine vasopressin receptor 1B involved_in ISO
IEA		 (PMID:9322919)
GO_REF:0000107		 RGD
Ensembl		 PMID:9322919 GO_REF:0000107 NCBI chr13:43,046,531...43,059,046
Ensembl chr13:43,046,267...43,057,792 		JBrowse link
G Cd244 CD244 molecule involved_in ISO (PMID:8376943) RGD PMID:8376943 NCBI chr13:84,051,339...84,082,864
Ensembl chr13:84,052,493...84,074,492 		JBrowse link
G Mas1 MAS1 proto-oncogene, G protein-coupled receptor IDA RGD PMID:1332507 RGD:2316794 NCBI chr 1:47,879,956...47,911,500
Ensembl chr 1:47,880,309...47,911,709 		JBrowse link
G Ntsr1 neurotensin receptor 1 IMP RGD PMID:11861328 RGD:9743897 NCBI chr 3:167,606,215...167,656,371
Ensembl chr 3:167,606,215...167,656,377 		JBrowse link
G Ptafr platelet-activating factor receptor IDA RGD PMID:8798508 RGD:9999203 NCBI chr 5:144,765,770...144,795,057
Ensembl chr 5:144,765,976...144,795,251 		JBrowse link
G Pth parathyroid hormone involved_in ISO (PMID:11604398) RGD PMID:11604398 NCBI chr 1:167,508,121...167,511,530
Ensembl chr 1:167,508,598...167,511,530 		JBrowse link
G Pth1r parathyroid hormone 1 receptor involved_in IDA PMID:19608645 BHF-UCL PMID:19608645 RGD:8553376 NCBI chr 8:110,693,910...110,725,458
Ensembl chr 8:110,697,485...110,719,729 		JBrowse link
G Snca synuclein alpha involved_in ISO
IEA		 (PMID:15641770)
GO_REF:0000107		 RGD
Ensembl		 PMID:15641770 GO_REF:0000107 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262 		JBrowse link
positive regulation of inositol trisphosphate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gper1 G protein-coupled estrogen receptor 1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:15705806)		 UniProt
Ensembl
RGD		 PMID:15705806 GO_REF:0000024 GO_REF:0000107 NCBI chr12:15,217,217...15,222,679
Ensembl chr12:15,217,442...15,221,889 		JBrowse link
G Lhcgr luteinizing hormone/choriogonadotropin receptor involved_in IEA
ISO		 GO_REF:0000107
(MGI:5318037|PMID:10493819)		 Ensembl
RGD		 PMID:10493819 GO_REF:0000107 MGI:5318037 NCBI chr 6:5,661,871...5,728,109
Ensembl chr 6:5,661,871...5,724,521 		JBrowse link
G Myh9 myosin, heavy chain 9 IMP RGD PMID:20068007 RGD:6902910 NCBI chr 7:109,343,718...109,424,457
Ensembl chr 7:109,343,706...109,424,457 		JBrowse link
G P2ry1 purinergic receptor P2Y1 involved_in IDA PMID:11390975 BHF-UCL PMID:11390975 RGD:8553380 NCBI chr 2:145,241,975...145,248,186
Ensembl chr 2:145,241,849...145,248,457 		JBrowse link
G P2ry6 pyrimidinergic receptor P2Y6 involved_in ISO (PMID:8670200) RGD PMID:8670200 NCBI chr 1:155,295,110...155,330,610
Ensembl chr 1:155,295,111...155,330,808 		JBrowse link
G Plcd1 phospholipase C, delta 1 IMP RGD PMID:16709602 RGD:2300424 NCBI chr 8:118,795,196...118,818,186
Ensembl chr 8:118,795,201...118,818,186 		JBrowse link
G Pou1f1 POU class 1 homeobox 1 acts_upstream_of_or_within ISO MGI:1856024|MGI:1856025 (PMID:11371619) RGD PMID:11371619 NCBI chr11:3,316,818...3,334,804
Ensembl chr11:3,317,058...3,334,801 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19692
    metabolic process 11456
      organic substance metabolic process 10970
        organic substance biosynthetic process 8107
          organophosphate biosynthetic process 538
            inositol phosphate biosynthetic process 30
              inositol trisphosphate biosynthetic process + 11
              myo-inositol hexakisphosphate biosynthetic process + 0
              negative regulation of inositol phosphate biosynthetic process + 2
              positive regulation of inositol phosphate biosynthetic process + 16
              regulation of inositol phosphate biosynthetic process + 18
Path 2
Term Annotations click to browse term
  biological_process 19692
    metabolic process 11456
      biosynthetic process 8172
        organic substance biosynthetic process 8107
          organic hydroxy compound biosynthetic process 253
            alcohol biosynthetic process 152
              polyol biosynthetic process 68
                inositol phosphate biosynthetic process 30
                  inositol trisphosphate biosynthetic process + 11
                  myo-inositol hexakisphosphate biosynthetic process + 0
                  negative regulation of inositol phosphate biosynthetic process + 2
                  positive regulation of inositol phosphate biosynthetic process + 16
                  regulation of inositol phosphate biosynthetic process + 18
paths to the root