Ipmk (inositol polyphosphate multikinase) - Rat Genome Database

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Gene: Ipmk (inositol polyphosphate multikinase) Rattus norvegicus
Analyze
Symbol: Ipmk
Name: inositol polyphosphate multikinase
RGD ID: 620954
Description: Enables phosphatidylinositol-4,5-bisphosphate 3-kinase activity. Predicted to be involved in inositol phosphate biosynthetic process; inositol trisphosphate metabolic process; and necroptotic process. Predicted to act upstream of or within neural tube formation. Located in nucleus. Orthologous to human IPMK (inositol polyphosphate multikinase); PARTICIPATES IN inositol metabolic pathway; inositol phosphate metabolic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane; ammonium chloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Impk; inositol 1,3,4,6-tetrakisphosphate 5-kinase; inositol polyphosphate kinase 2; Ipk2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22017,216,988 - 17,251,675 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl2017,218,037 - 17,251,705 (-)Ensembl
Rnor_6.02018,457,309 - 18,489,884 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2018,457,310 - 18,489,833 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02020,623,398 - 20,655,968 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42017,947,110 - 17,982,280 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12017,960,909 - 17,996,075 (-)NCBI
Celera2018,616,391 - 18,650,911 (-)NCBICelera
Cytogenetic Map20p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
6. Inositol polyphosphate multikinase is a nuclear PI3-kinase with transcriptional regulatory activity. Resnick AC, etal., Proc Natl Acad Sci U S A. 2005 Sep 6;102(36):12783-8. doi: 10.1073/pnas.0506184102. Epub 2005 Aug 25.
7. GOA pipeline RGD automated data pipeline
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Mammalian inositol polyphosphate multikinase synthesizes inositol 1,4,5-trisphosphate and an inositol pyrophosphate. Saiardi A, etal., Proc Natl Acad Sci U S A 2001 Feb 27;98(5):2306-11.
Additional References at PubMed
PMID:15528195   PMID:15939867   PMID:22940627   PMID:29883610   PMID:30624931  


Genomics

Comparative Map Data
Ipmk
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22017,216,988 - 17,251,675 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl2017,218,037 - 17,251,705 (-)Ensembl
Rnor_6.02018,457,309 - 18,489,884 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2018,457,310 - 18,489,833 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02020,623,398 - 20,655,968 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42017,947,110 - 17,982,280 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12017,960,909 - 17,996,075 (-)NCBI
Celera2018,616,391 - 18,650,911 (-)NCBICelera
Cytogenetic Map20p11NCBI
IPMK
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381058,191,517 - 58,267,894 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1058,191,517 - 58,267,894 (-)EnsemblGRCh38hg38GRCh38
GRCh371059,951,278 - 60,027,654 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361059,625,620 - 59,697,700 (-)NCBINCBI36hg18NCBI36
Build 341059,625,623 - 59,697,700NCBI
Celera1053,220,872 - 53,292,609 (-)NCBI
Cytogenetic Map10q21.1NCBI
HuRef1053,940,146 - 54,016,565 (-)NCBIHuRef
CHM1_11060,233,052 - 60,309,470 (-)NCBICHM1_1
T2T-CHM13v2.01059,045,622 - 59,122,002 (-)NCBI
Ipmk
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391071,183,574 - 71,221,715 (+)NCBIGRCm39mm39
GRCm39 Ensembl1071,183,593 - 71,269,157 (+)Ensembl
GRCm381071,347,744 - 71,385,885 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1071,347,763 - 71,433,327 (+)EnsemblGRCm38mm10GRCm38
MGSCv371070,810,541 - 70,848,633 (+)NCBIGRCm37mm9NCBIm37
MGSCv361070,743,093 - 70,781,185 (+)NCBImm8
Celera1072,422,991 - 72,461,090 (+)NCBICelera
Cytogenetic Map10B5.3NCBI
Ipmk
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542511,945,858 - 11,985,023 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542511,949,849 - 12,000,610 (-)NCBIChiLan1.0ChiLan1.0
IPMK
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11056,939,012 - 57,019,101 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1056,939,012 - 57,019,101 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01054,718,987 - 54,799,264 (-)NCBIMhudiblu_PPA_v0panPan3
IPMK
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Dog10K_Boxer_Tasha410,592,723 - 10,653,047 (-)NCBI
ROS_Cfam_1.0410,656,052 - 10,716,789 (-)NCBI
UMICH_Zoey_3.1410,641,291 - 10,701,561 (-)NCBI
UNSW_CanFamBas_1.0410,760,150 - 10,820,877 (-)NCBI
UU_Cfam_GSD_1.0411,070,009 - 11,130,339 (-)NCBI
Ipmk
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721370,638,694 - 70,690,520 (+)NCBI
SpeTri2.0NW_0049366144,724,935 - 4,772,373 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IPMK
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1492,383,517 - 92,428,730 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11492,383,471 - 92,428,732 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214100,992,513 - 100,996,199 (-)NCBISscrofa10.2Sscrofa10.2susScr3
IPMK
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1973,031,149 - 73,108,105 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl973,031,150 - 73,108,291 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604833,933,085 - 34,012,291 (+)NCBIVero_WHO_p1.0
Ipmk
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247915,325,413 - 5,387,912 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
D20Got11  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22017,224,194 - 17,224,327 (+)MAPPERmRatBN7.2
Rnor_6.02018,464,515 - 18,464,647NCBIRnor6.0
Rnor_5.02020,630,604 - 20,630,736UniSTSRnor5.0
RGSC_v3.42017,954,882 - 17,955,015RGDRGSC3.4
RGSC_v3.42017,954,316 - 17,954,449RGDRGSC3.4
RGSC_v3.42017,954,883 - 17,955,015UniSTSRGSC3.4
RGSC_v3.42017,954,317 - 17,954,449UniSTSRGSC3.4
RGSC_v3.12017,968,683 - 17,968,815RGD
Celera2018,623,596 - 18,623,728UniSTS
RH 3.4 Map20206.8UniSTS
RH 3.4 Map20206.8RGD
RH 2.0 Map20246.2RGD
Cytogenetic Map20p11UniSTS
RH129909  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22017,217,179 - 17,217,394 (+)MAPPERmRatBN7.2
Rnor_6.02018,457,501 - 18,457,715NCBIRnor6.0
Rnor_5.02020,623,590 - 20,623,804UniSTSRnor5.0
RGSC_v3.42017,947,302 - 17,947,516UniSTSRGSC3.4
Celera2018,616,583 - 18,616,797UniSTS
RH 3.4 Map20204.0UniSTS
Cytogenetic Map20p11UniSTS
RH131435  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22017,217,527 - 17,217,720 (+)MAPPERmRatBN7.2
Rnor_6.02018,457,849 - 18,458,041NCBIRnor6.0
Rnor_5.02020,623,938 - 20,624,130UniSTSRnor5.0
RGSC_v3.42017,947,650 - 17,947,842UniSTSRGSC3.4
Celera2018,616,931 - 18,617,123UniSTS
RH 3.4 Map20205.5UniSTS
Cytogenetic Map20p11UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354642Despr15Despair related QTL 150.0027locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)20124159021Rat
1600382Edcs3Endometrial carcinoma susceptibility QTL33.50.003uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)20125159026Rat
2317851Alcrsp22Alcohol response QTL 223.20.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127339237Rat
1641893Alcrsp7Alcohol response QTL 7response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127339237Rat
8694189Bw153Body weight QTL 1533.130.001body mass (VT:0001259)body weight gain (CMO:0000420)20129191651Rat
9590275Scort15Serum corticosterone level QTL 153.480.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20129191651Rat
7411650Foco23Food consumption QTL 2320.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20129191651Rat
9590109Sffal8Serum free fatty acids level QTL 85.320.01blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)20129191651Rat
9589155Insul32Insulin level QTL 326.380.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)20129191651Rat
6893685Bw111Body weight QTL 1112.70.004body mass (VT:0001259)body weight (CMO:0000012)20132578807Rat
7411668Foco32Food consumption QTL 3280.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20136600972Rat
9590252Scort12Serum corticosterone level QTL 1220.460.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20136600972Rat
2305926Iddm37Insulin dependent diabetes mellitus QTL 376blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)20152784246527842Rat
1641915Colcr9Colorectal carcinoma resistance QTL 92.970.0024intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)20153065546530655Rat
1598816Memor12Memory QTL 122.4exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)20260683647606836Rat
2317057Aia27Adjuvant induced arthritis QTL 272.83joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)20289259726381954Rat
4889857Pur27Proteinuria QTL 2712.20.001total urine protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)20460660717617956Rat
1558640Prcs2Prostate cancer susceptibility QTL 23.3prostate integrity trait (VT:0010571)percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)20460660717617956Rat
70154Insul2Insulin level QTL 23.75blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)20669170617489458Rat
1581577Pur15Proteinuria QTL 154.380.0002total urine protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)20804241017617956Rat
4889870Pur30Proteinuria QTL 30190.005total urine protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)20804241029322208Rat
7411652Foco24Food consumption QTL 240.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)201175751554435887Rat
9590092Insglur9Insulin/glucose ratio QTL 918.380.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)201175751554435887Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:672
Count of miRNA genes:286
Interacting mature miRNAs:382
Transcripts:ENSRNOT00000000748
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 2 2 2 1 2 66 35 12 11
Low 41 55 39 18 39 8 11 8 29 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000000748   ⟹   ENSRNOP00000000748
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2017,218,037 - 17,251,595 (-)Ensembl
Rnor_6.0 Ensembl2018,457,310 - 18,489,833 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000105838   ⟹   ENSRNOP00000093022
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2017,218,037 - 17,251,705 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000107068   ⟹   ENSRNOP00000092735
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2017,225,506 - 17,251,595 (-)Ensembl
RefSeq Acc Id: NM_134417   ⟹   NP_599244
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22017,216,988 - 17,251,595 (-)NCBI
Rnor_6.02018,457,309 - 18,489,833 (-)NCBI
Rnor_5.02020,623,398 - 20,655,968 (-)NCBI
RGSC_v3.42017,947,110 - 17,982,280 (-)RGD
Celera2018,616,391 - 18,650,911 (-)RGD
Sequence:
RefSeq Acc Id: XM_006256345   ⟹   XP_006256407
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22017,216,988 - 17,251,675 (-)NCBI
Rnor_6.02018,457,309 - 18,489,884 (-)NCBI
Rnor_5.02020,623,398 - 20,655,968 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006256346   ⟹   XP_006256408
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22017,216,988 - 17,237,801 (-)NCBI
Rnor_6.02018,457,309 - 18,476,573 (-)NCBI
Rnor_5.02020,623,398 - 20,655,968 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039098407   ⟹   XP_038954335
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22017,216,988 - 17,250,518 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_599244   ⟸   NM_134417
- UniProtKB: Q99NI4 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006256407   ⟸   XM_006256345
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006256408   ⟸   XM_006256346
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSRNOP00000000748   ⟸   ENSRNOT00000000748
RefSeq Acc Id: XP_038954335   ⟸   XM_039098407
- Peptide Label: isoform X3
RefSeq Acc Id: ENSRNOP00000092735   ⟸   ENSRNOT00000107068
RefSeq Acc Id: ENSRNOP00000093022   ⟸   ENSRNOT00000105838

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q99NI4-F1-model_v2 AlphaFold Q99NI4 1-396 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701551
Promoter ID:EPDNEW_R12074
Type:multiple initiation site
Name:Ipmk_1
Description:inositol polyphosphate multikinase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.02018,489,838 - 18,489,898EPDNEW

Strain Variation

Strain Sequence Variants (MRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
Damaging Variants


Assembly: Rnor_6.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
20 18467706 18467707 T G snv HXB20/IpcvMcwi (2020)
20 18467707 18467708 T G snv HXB20/IpcvMcwi (2020)


Assembly: Rnor_5.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
20 20627812 20627813 G A snv HTX/Kyo (KyushuU)


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620954 AgrOrtholog
BioCyc Gene G2FUF-4050 BioCyc
BioCyc Pathway PWY-6361 [1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)] BioCyc
Ensembl Genes ENSRNOG00000000609 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000000748 ENTREZGENE
  ENSRNOP00000092735.1 UniProtKB/TrEMBL
  ENSRNOP00000093022.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000000748 ENTREZGENE
  ENSRNOT00000105838.1 UniProtKB/TrEMBL
  ENSRNOT00000107068.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.470.160 UniProtKB/Swiss-Prot
InterPro IPK UniProtKB/Swiss-Prot
  IPK_sf UniProtKB/Swiss-Prot
KEGG Report rno:171458 UniProtKB/Swiss-Prot
NCBI Gene 171458 ENTREZGENE
PANTHER PTHR12400 UniProtKB/Swiss-Prot
Pfam IPK UniProtKB/Swiss-Prot
PhenoGen Ipmk PhenoGen
UniProt A0A8I6AEH2_RAT UniProtKB/TrEMBL
  A0A8I6AI58_RAT UniProtKB/TrEMBL
  IPMK_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2006-03-30 Ipmk  inositol polyphosphate multikinase  Impk    Symbol updated 1299863 APPROVED
2004-09-10 Impk  inositol polyphosphate multikinase  Ipmk    Symbol updated 1299863 APPROVED
2002-08-07 Ipmk  inositol polyphosphate multikinase      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_protein 44-kDa protein 633148