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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of interferon-alpha production
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Accession:GO:0032727 term browser browse the term
Definition:Any process that activates or increases the frequency, rate, or extent of interferon-alpha production.
Synonyms:exact_synonym: up regulation of interferon-alpha production;   upregulation of interferon-alpha production
 narrow_synonym: activation of interferon-alpha production;   positive regulation of interferon-alpha biosynthetic process;   positive regulation of interferon-alpha secretion;   stimulation of interferon-alpha production
 alt_id: GO:0045356;   GO:1902741
 only_in_taxon: NCBITaxon:6072 ! Eumetazoa



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positive regulation of interferon-alpha production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chuk component of inhibitor of nuclear factor kappa B kinase complex involved_in ISO (PMID:24784232) RGD PMID:24784232 NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065
JBrowse link
G Ddx3x DEAD-box helicase 3, X-linked involved_in ISO (PMID:30341167) RGD PMID:30341167 NCBI chr  X:9,479,532...9,493,169
Ensembl chr  X:9,479,532...9,493,168
JBrowse link
G Dhx36 DEAH-box helicase 36 involved_in ISO (PMID:20696886) RGD PMID:20696886 NCBI chr 2:146,856,469...146,894,577
Ensembl chr 2:146,856,469...146,894,572
JBrowse link
G Dhx9 DExH-box helicase 9 involved_in ISO (PMID:21957149) RGD PMID:21957149 NCBI chr13:65,602,322...65,639,098
Ensembl chr13:65,602,323...65,639,069
JBrowse link
G Flt3 Fms related receptor tyrosine kinase 3 acts_upstream_of_or_within ISO MGI:3628823 (PMID:20457904) RGD PMID:20457904 NCBI chr12:7,623,930...7,699,474
Ensembl chr12:7,623,930...7,699,474
JBrowse link
G Hmgb1 high mobility group box 1 involved_in ISO (PMID:19890330) RGD PMID:19890330 NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 involved_in
acts_upstream_of_or_within
ISO
IBA
(PMID:17164250)
GO_REF:0000033
RGD
GO_Central
PMID:17164250 GO_REF:0000033 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
JBrowse link
G Ifih1 interferon induced with helicase C domain 1 involved_in ISO (PMID:19656871), (PMID:21957149) RGD PMID:19656871 PMID:21957149 NCBI chr 3:47,228,980...47,275,403
Ensembl chr 3:47,227,364...47,275,456
JBrowse link
G Irf3 interferon regulatory factor 3 involved_in ISO (PMID:18562536) RGD PMID:18562536 NCBI chr 1:95,479,966...95,484,926
Ensembl chr 1:95,479,821...95,484,935
JBrowse link
G Irf7 interferon regulatory factor 7 involved_in ISO (PMID:16127453) RGD PMID:16127453 NCBI chr 1:196,367,380...196,370,943
Ensembl chr 1:196,367,361...196,370,832
JBrowse link
G Mavs mitochondrial antiviral signaling protein involved_in
acts_upstream_of_or_within
ISO
ISS
(PMID:16127453), (PMID:19609254), (PMID:21957149)
GO_REF:0000024
MGI:6430641 (PMID:31390091)
RGD
UniProt
PMID:16127453 PMID:19609254 PMID:21957149 PMID:31390091 GO_REF:0000024 NCBI chr 3:118,451,650...118,466,094
Ensembl chr 3:118,451,743...118,466,094
JBrowse link
G Mmp12 matrix metallopeptidase 12 involved_in IEA
ISO
GO_REF:0000107
(PMID:24784232)
Ensembl
RGD
PMID:24784232 GO_REF:0000107 NCBI chr 8:4,581,785...4,591,687
Ensembl chr 8:4,581,785...4,599,611
JBrowse link
G Nmb neuromedin B involved_in ISO (PMID:31601264) RGD PMID:31601264 NCBI chr 1:134,869,446...134,875,507
Ensembl chr 1:134,869,446...134,872,190
JBrowse link
G Nmbr neuromedin B receptor involved_in ISO
IEA
(PMID:31601264)
GO_REF:0000107
RGD
Ensembl
PMID:31601264 GO_REF:0000107 NCBI chr 1:9,115,033...9,146,081
Ensembl chr 1:9,134,889...9,145,462
JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 involved_in ISO (PMID:23871208) RGD PMID:23871208 NCBI chr 2:191,366,761...191,414,782
Ensembl chr 2:191,366,808...191,414,779
JBrowse link
G Rig1 RNA sensor RIG-1 involved_in ISO (PMID:19576794), (PMID:19609254), (PMID:21957149) RGD PMID:19576794 PMID:19609254 PMID:21957149 NCBI chr 5:55,321,351...55,369,947
Ensembl chr 5:55,321,235...55,370,819
JBrowse link
G Setd2 SET domain containing 2, histone lysine methyltransferase involved_in ISO (PMID:28753426) RGD PMID:28753426 NCBI chr 8:110,511,808...110,597,475
Ensembl chr 8:110,511,772...110,597,489
JBrowse link
G Stat1 signal transducer and activator of transcription 1 involved_in ISO (PMID:28753426) RGD PMID:28753426 NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540
JBrowse link
G Tbk1 TANK-binding kinase 1 involved_in ISO (PMID:16127453) RGD PMID:16127453 NCBI chr 7:57,077,830...57,110,868
Ensembl chr 7:57,077,830...57,110,892
JBrowse link
G Tlr3 toll-like receptor 3 involved_in ISO (PMID:16286015) RGD PMID:16286015 NCBI chr16:46,821,980...46,837,900
Ensembl chr16:46,822,039...46,836,545
JBrowse link
G Tlr4 toll-like receptor 4 involved_in IEA
ISO
GO_REF:0000107
(PMID:15356140)
Ensembl
RGD
PMID:15356140 GO_REF:0000107 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tlr7 toll-like receptor 7 involved_in ISO (PMID:16286015)
(PMID:14976261)
RGD PMID:14976261 PMID:16286015 NCBI chr  X:27,027,380...27,054,309
Ensembl chr  X:27,027,425...27,054,754
JBrowse link
G Tlr8 toll-like receptor 8 involved_in ISO (PMID:16286015) RGD PMID:16286015 NCBI chr  X:27,091,780...27,116,092
Ensembl chr  X:27,091,778...27,116,549
JBrowse link
G Tlr9 toll-like receptor 9 involved_in ISO (PMID:16286015) RGD PMID:16286015 NCBI chr 8:106,864,680...106,868,796
Ensembl chr 8:106,864,680...106,868,796
JBrowse link
G Traf3ip3 TRAF3 interacting protein 3 acts_upstream_of_or_within ISO MGI:5795738 (PMID:31390091) RGD PMID:31390091 NCBI chr13:104,694,802...104,719,655
Ensembl chr13:104,694,805...104,719,673
JBrowse link
G Trim65 tripartite motif-containing 65 acts_upstream_of_or_within ISO MGI:6356825|MGI:6356826|MGI:6356827 (PMID:28031478) RGD PMID:28031478 NCBI chr10:101,357,937...101,364,036
Ensembl chr10:101,357,937...101,364,971
JBrowse link
G Zc3hav1 zinc finger CCCH-type containing, antiviral 1 involved_in ISO (PMID:21102435) RGD PMID:21102435 NCBI chr 4:67,012,129...67,062,428
Ensembl chr 4:67,012,185...67,062,428
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20069
    multicellular organismal process 8906
      positive regulation of multicellular organismal process 1895
        positive regulation of cytokine production 535
          positive regulation of type I interferon production 78
            positive regulation of interferon-alpha production 27
Path 2
Term Annotations click to browse term
  biological_process 20069
    biological regulation 13555
      regulation of biological process 13132
        regulation of cellular process 12767
          regulation of metabolic process 6743
            regulation of biosynthetic process 5507
              regulation of macromolecule biosynthetic process 5306
                regulation of gene expression 5186
                  regulation of cytokine production 906
                    positive regulation of cytokine production 535
                      positive regulation of type I interferon production 78
                        positive regulation of interferon-alpha production 27
paths to the root