Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

ONTOLOGY REPORT - ANNOTATIONS

Term:response to acidic pH
go back to main search page
Accession:GO:0010447 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH < 7. pH is a measure of the acidity or basicity of an aqueous solution.
Comment:This term should be used to annotate instances where a cell or organism is responding to a chemical that is playing the role of an acid (e.g. proton donor) and therefore lowering the pH. If instead you wish to describe a response to a specific acid as a chemical, such as the anion portion of glutamate, please annotate to the appropriate child of GO:0001101 'response to acid chemical'.
Synonyms:broad_synonym: response to acidity


show annotations for term's descendants           Sort by:
response to acidic pH term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acan aggrecan IEP RGD PMID:19133233 RGD:2315756 NCBI chr 1:142,390,951...142,453,779
Ensembl chr 1:132,981,582...133,043,627 		JBrowse link
G Asic1 acid sensing ion channel subunit 1 acts_upstream_of_or_within ISO MGI:2179834 (PMID:11854527), (PMID:11988176) RGD PMID:11854527 PMID:11988176 NCBI chr 7:130,798,317...130,828,535
Ensembl chr 7:130,799,917...130,828,541 		JBrowse link
G Asic2 acid sensing ion channel subunit 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2180111 (PMID:11306621), (PMID:11854527)		 Ensembl
RGD		 PMID:11306621 PMID:11854527 GO_REF:0000107 NCBI chr10:66,368,308...67,438,237
Ensembl chr10:65,870,594...66,940,424 		JBrowse link
G Asic3 acid sensing ion channel subunit 3 acts_upstream_of_or_within IDA
ISO		 PMID:9261094
MGI:2429689|MGI:2451051 (PMID:11754838), (PMID:11854527), (PMID:12060708)		 RGD PMID:11754838 PMID:11854527 PMID:12060708 PMID:9261094 RGD:1299543 NCBI chr 4:10,760,509...10,764,987
Ensembl chr 4:10,760,597...10,764,643 		JBrowse link
G Ctss cathepsin S involved_in ISO
IEA		 (PMID:22864553)
GO_REF:0000107		 RGD
Ensembl		 PMID:22864553 GO_REF:0000107 NCBI chr 2:185,775,316...185,803,440
Ensembl chr 2:183,086,437...183,114,483 		JBrowse link
G Gip gastric inhibitory polypeptide IMP HCl RGD PMID:34554 RGD:2312536 NCBI chr10:81,465,070...81,473,216
Ensembl chr10:80,968,352...80,976,503 		JBrowse link
G Gpr151 G protein-coupled receptor 151 involved_in ISO (PMID:31119277) RGD PMID:31119277 NCBI chr18:34,568,907...34,570,301
Ensembl chr18:34,568,907...34,570,301 		JBrowse link
G Gpr31 G protein-coupled receptor 31 involved_in ISO (PMID:31119277) RGD PMID:31119277 NCBI chr 1:55,474,484...55,475,443 JBrowse link
G Gpr4 G protein-coupled receptor 4 involved_in
acts_upstream_of_or_within		 ISO
ISS		 (PMID:12955148), (PMID:17462861), (PMID:22110680)
MGI:3700206 (PMID:17145776)
GO_REF:0000024		 RGD
UniProt		 PMID:12955148 PMID:17145776 PMID:17462861 PMID:22110680 GO_REF:0000024 NCBI chr 1:78,865,376...78,877,126
Ensembl chr 1:78,865,409...78,876,599 		JBrowse link
G Gpr65 G-protein coupled receptor 65 involved_in ISO (PMID:15618224) RGD PMID:15618224 NCBI chr 6:123,245,534...123,262,758
Ensembl chr 6:117,515,648...117,536,512 		JBrowse link
G Lgmn legumain involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:18374643)
GO_REF:0000107
(PMID:25326800)
MGI:2676125 (PMID:18374643)
(PMID:9065484)		 RGD
Ensembl		 PMID:9065484 PMID:18374643 PMID:25326800 GO_REF:0000107 NCBI chr 6:127,308,913...127,347,355
Ensembl chr 6:121,544,053...121,582,480 		JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase IEP HCl RGD PMID:7729276 RGD:2317551 NCBI chr 4:46,756,823...46,864,041
Ensembl chr 4:45,790,791...45,897,876 		JBrowse link
G Serpinf1 serpin family F member 1 IEP RGD PMID:19575033 RGD:8554877 NCBI chr10:60,748,504...60,760,898
Ensembl chr10:60,249,708...60,262,646 		JBrowse link
G Slc4a1 solute carrier family 4 member 1 (Diego blood group) IEP RGD PMID:10600930 RGD:13208945 NCBI chr10:87,807,010...87,823,274
Ensembl chr10:87,306,872...87,323,117 		JBrowse link
G Slc9a1 solute carrier family 9 member A1 involved_in
acts_upstream_of_or_within		 IDA
ISO
ISS		 PMID:18321853
MGI:2429323 (PMID:10673550)
(PMID:8901634)
GO_REF:0000024		 RGD
UniProt		 PMID:8901634 PMID:10673550 PMID:18321853 GO_REF:0000024, RGD:8554433 NCBI chr 5:150,859,412...150,913,525
Ensembl chr 5:145,576,334...145,629,624 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase IEP RGD PMID:12081562 RGD:634206 NCBI chr 3:166,511,616...166,559,463
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
G Sst somatostatin IEP HCl RGD PMID:18992283 RGD:2303157 NCBI chr11:90,461,546...90,462,823
Ensembl chr11:76,956,896...76,958,173 		JBrowse link
G Stxbp2 syntaxin binding protein 2 IEP RGD PMID:15240346 RGD:2312428 NCBI chr12:6,487,265...6,498,351
Ensembl chr12:1,689,410...1,700,458 		JBrowse link
cellular response to acidic pH term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asic2 acid sensing ion channel subunit 2 IDA RGD PMID:12736332 RGD:1298620 NCBI chr10:66,368,308...67,438,237
Ensembl chr10:65,870,594...66,940,424 		JBrowse link
G Chp1 calcineurin-like EF-hand protein 1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 3:126,989,800...127,025,071
Ensembl chr 3:106,536,004...106,571,251 		JBrowse link
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 IEP RGD PMID:26033523 RGD:13204712 NCBI chr 1:22,518,051...22,583,044
Ensembl chr 1:20,698,764...20,763,715 		JBrowse link
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 IDA RGD PMID:8458414 RGD:7243874 NCBI chr11:45,066,875...45,080,024
Ensembl chr11:31,580,742...31,593,901 		JBrowse link
G Kcnk1 potassium two pore domain channel subfamily K member 1 involved_in IDA PMID:22948150 UniProt PMID:22948150 RGD:408345197 NCBI chr19:70,856,985...70,895,053
Ensembl chr19:53,959,657...53,997,724 		JBrowse link
G Kcnk3 potassium two pore domain channel subfamily K member 3 involved_in ISO (PMID:22948150) RGD PMID:22948150 NCBI chr 6:31,483,129...31,519,061
Ensembl chr 6:25,763,228...25,799,153 		JBrowse link
G Kcnk4 potassium two pore domain channel subfamily K member 4 involved_in ISS
ISO		 GO_REF:0000024
(PMID:26919430)		 UniProt
RGD		 PMID:26919430 GO_REF:0000024 NCBI chr 1:204,117,941...204,129,494
Ensembl chr 1:204,114,572...204,125,925 		JBrowse link
G Kcnk9 potassium two pore domain channel subfamily K member 9 involved_in ISO (PMID:22948150), (PMID:38630723) RGD PMID:22948150 PMID:38630723 NCBI chr 7:104,429,186...104,473,924
Ensembl chr 7:104,437,934...104,473,175 		JBrowse link
G Pkd1l3 polycystin 1 like 3, transient receptor potential channel interacting NOT|involved_in ISO (PMID:20605874)
(PMID:16891422)		 RGD PMID:16891422 PMID:20605874 NCBI chr19:37,585,564...37,650,083
Ensembl chr19:37,585,725...37,650,155 		JBrowse link
G Pkd2l1 polycystin 2 like 1, transient receptor potential cation channel involved_in ISO (PMID:16891422), (PMID:29567962) RGD PMID:16891422 PMID:29567962 NCBI chr 1:252,982,096...253,019,235
Ensembl chr 1:243,032,913...243,070,031 		JBrowse link
G Rab11b RAB11B, member RAS oncogene family involved_in ISO
ISS		 (PMID:20717956)
GO_REF:0000024		 RGD
UniProt		 PMID:20717956 GO_REF:0000024 NCBI chr 7:15,223,613...15,236,754
Ensembl chr 7:14,521,368...14,534,593 		JBrowse link
G Rab11fip5 RAB11 family interacting protein 5 involved_in ISO (PMID:20717956) RGD PMID:20717956 NCBI chr 4:119,428,766...119,466,277
Ensembl chr 4:117,871,308...117,908,741 		JBrowse link
G Scnn1a sodium channel epithelial 1 subunit alpha involved_in ISO
IEA		 (PMID:16423824)
GO_REF:0000107		 RGD
Ensembl		 PMID:16423824 GO_REF:0000107 NCBI chr 4:159,809,187...159,832,409
Ensembl chr 4:158,122,962...158,146,181 		JBrowse link
G Scnn1b sodium channel epithelial 1 subunit beta involved_in ISO
IEA		 (PMID:16423824)
GO_REF:0000107		 RGD
Ensembl		 PMID:16423824 GO_REF:0000107 NCBI chr 1:185,861,326...185,915,717
Ensembl chr 1:176,430,103...176,484,451 		JBrowse link
G Scnn1g sodium channel epithelial 1 subunit gamma involved_in ISO
IEA		 (PMID:16423824)
GO_REF:0000107		 RGD
Ensembl		 PMID:16423824 GO_REF:0000107 NCBI chr 1:185,736,225...185,770,099
Ensembl chr 1:176,304,942...176,338,816 		JBrowse link
G Slc9a1 solute carrier family 9 member A1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:24840010)		 UniProt
RGD		 PMID:24840010 GO_REF:0000024 NCBI chr 5:150,859,412...150,913,525
Ensembl chr 5:145,576,334...145,629,624 		JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 involved_in ISO
IDA		 (PMID:11226139) RGD PMID:11226139 PMID:11226139 RGD:11535102 NCBI chr10:58,349,936...58,375,021
Ensembl chr10:57,851,428...57,876,513 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20536
    response to stimulus 11014
      response to abiotic stimulus 1597
        response to pH 58
          response to acidic pH 33
            cellular response to acidic pH + 17
paths to the root